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ARAQKCTVGVTDAVDETESGTVAGGAEGRRPRSLTRAEILDTAIALVDSEGLDQLTMRRLGSACGVEAMA LYRHVHGRQDLLGGIVDHLVDKLYDDQLAARRQEDGWQDYLVRLAHGVREIAIGHPHLFPTLATRPPEAP WVRPPLRSMKWMETFLDTLISYGFDDRAAVSAYRAYTTFLLGQLLLEVSARGASLSSVEDELPEKTLRSL SSYPNLQRMQKQLSEDHSATEFEEALESLLDRLENGAPR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_3216c | - | - | 100% (250) | TetR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_0856c | - | 4e-11 | 25.93% (216) | TetR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_2685 | - | 8e-10 | 30.43% (115) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0700 | - | 2e-09 | 26.54% (162) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_5079 | - | 9e-10 | 29.27% (164) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0681 | - | 2e-09 | 26.54% (162) | TetR family transcriptional regulator |
| M. leprae Br4923 | - | - | - | - | - |
| M. marinum M | MMAR_1010 | - | 2e-10 | 27.16% (162) | TetR family transcriptional regulator |
| M. avium 104 | MAV_4494 | - | 1e-10 | 26.29% (175) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_3332 | - | 2e-22 | 35.09% (171) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_0654 | - | 7e-10 | 27.22% (169) | transcriptional regulator, TetR family protein |
| M. ulcerans Agy99 | MUL_0762 | - | 1e-10 | 27.16% (162) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_1315 | - | 1e-12 | 29.70% (165) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0700|M.bovis_AF2122/97 ---------------------------------------MARPAKLSRES
Rv0681|M.tuberculosis_H37Rv ---------------------------------------MARPAKLSRES
MAV_4494|M.avium_104 --------------------MAAQPEPPTAAGRQRAGRPAARPAKLSREG
MMAR_1010|M.marinum_M --------------------MAASAEGPSAAGRPRAAKSTSRPAKLSRDA
MUL_0762|M.ulcerans_Agy99 --------------------MAASAEGPSAAGRPRAAKSTSRPAKLSRDA
Mflv_5079|M.gilvum_PYR-GCK --------------------MAARP---------------PRTAKLSRDS
MAB_3216c|M.abscessus_ATCC_199 -----------MARAQKCTVGVTDAVDETESGTVAGGAEGRRPRSLTRAE
MSMEG_3332|M.smegmatis_MC2_155 -----------------MTQPPAGPSGPGDSAPSADATENGQNRPITREA
Mvan_1315|M.vanbaalenii_PYR-1 MSYAHGCTAVRLDRMTNEEERGTPPLPRALEVLWHDRAGGGRARRLSRQR
TH_0654|M.thermoresistible__bu -------------------------------------------VQLRKSD
: :
Mb0700|M.bovis_AF2122/97 IVEGALTFLDREGWDSLTINALATQLGTKGPSLYNHVDSLEDLRRAVRIR
Rv0681|M.tuberculosis_H37Rv IVEGALTFLDREGWDSLTINALATQLGTKGPSLYNHVDSLEDLRRAVRIR
MAV_4494|M.avium_104 IIDGALTFLDREGWDALTINALATQLGTKGPSLYNHVDSLEDLRRAVRIR
MMAR_1010|M.marinum_M IVDGALTFLDREGWDSLTINALATQLGTKGPSLYNHVVSLEDLRGAVRVR
MUL_0762|M.ulcerans_Agy99 IVDGALTFLDREGWDSLTINALATQLGTKGPSLYNHVVSLEDLRGAVRVR
Mflv_5079|M.gilvum_PYR-GCK IVNAALTFLDREGWDALTINALANQLGTKGPSLYNHVHSLDDLRRTVRMR
MAB_3216c|M.abscessus_ATCC_199 ILDTAIALVDSEGLDQLTMRRLGSACGVEAMALYRHVHGRQDLLGGIVDH
MSMEG_3332|M.smegmatis_MC2_155 VLAGALDIIDRDGVDALSMRRLGEALGRDPMALYRHVPN----KAAVLDG
Mvan_1315|M.vanbaalenii_PYR-1 IVEAAIELADRDGLGALSMARLAERLGCGTMSLYRHVANKDELVTFMVSA
TH_0654|M.thermoresistible__bu VVDAATAILDNYGIADLTTRRLARELGVTAGALYWHFANKQELLGAVADR
:: * : * * *: *. * :** *. . :
Mb0700|M.bovis_AF2122/97 VIDDIIT-MLNRVGAGRARDDAVLVMAGAYRSYAHHHPGRYSAFTRMPLG
Rv0681|M.tuberculosis_H37Rv VIDDIIT-MLNRVGAGRARDDAVLVMAGAYRSYAHHHPGRYSAFTRMPLG
MAV_4494|M.avium_104 VIDDIIT-MLNRVGEGRARDDAVLVMAGAYRSYAHHHPGRYSAFTRMPLG
MMAR_1010|M.marinum_M VIDDIIM-MLNRVGEGRSRDDAVLVMAGAYRSYAHHHPGRYSAFTRMPPG
MUL_0762|M.ulcerans_Agy99 VIDDIIM-MLNRVGEGRSRDDAVLVMAGAYRSYAHHHPGRYSAFTRMPPG
Mflv_5079|M.gilvum_PYR-GCK VVGDIID-MLNTVAQGRNPDDAVVVMASAYRSYAHHHPGRYSAFTRMPLG
MAB_3216c|M.abscessus_ATCC_199 LVDKLYDDQLAARRQEDGWQDYLVRLAHGVREIAIGHPHLFPTLATRPPE
MSMEG_3332|M.smegmatis_MC2_155 VVEMIFE-QLSLDTTTPDWIAALRRLGHDFRNLARAHPNVVPLLVTRPLA
Mvan_1315|M.vanbaalenii_PYR-1 APGHPPG-----TTDRADWRDALTDWAVGLWDVYHRHPWILHATVIGPPA
TH_0654|M.thermoresistible__bu ILTPVPA-----GEPEPGWAERISSTAGRLRDALLSHTDGAELVSATFAA
: . . *.
Mb0700|M.bovis_AF2122/97 G-DDPEYTAATRGAAAPVIAVLSSYGLDGEQAFYAALEFWSALHGFVLLE
Rv0681|M.tuberculosis_H37Rv G-DDPEYTAATRGAAAPVIAVLSSYGLDGEQAFYAALEFWSALHGFVLLE
MAV_4494|M.avium_104 G-DDPEYTAATRGAAAPVISVLSSYGLDGEEAFHAALEFWSALHGFVLLE
MMAR_1010|M.marinum_M G-EDPEYAAATRAAAAPVIAVLSSYGLEGEQAFHAALEFWSALHGFVLLE
MUL_0762|M.ulcerans_Agy99 G-EDPEYAAATRAAAAPVIAVLSSYGLEGEQAFHAALEFWSALHGFVLLE
Mflv_5079|M.gilvum_PYR-GCK GGDDPEFTEVTRAAAAPVIAVLSSYGLDDEAGFYAALEFWSAMHGFVLLE
MAB_3216c|M.abscessus_ATCC_199 A-PWVRPPLRSMKWMETFLDTLISYGFDDRAAVSAYRAYTTFLLGQLLLE
MSMEG_3332|M.smegmatis_MC2_155 T-PLGMRPPGILRHLEQILALLTRCGFTGPDALHVYRTLFGFLYGHVLTE
Mvan_1315|M.vanbaalenii_PYR-1 D-------PGQLAWLDAGLAALSGTGLSERDKLAAVMALLHFVRGASALD
TH_0654|M.thermoresistible__bu G-----QSRVLDEILARFAAAAAAAGLEGSRAVLAARTIVHYVLGFTGDE
*: . . : * :
Mb0700|M.bovis_AF2122/97 MTG--------VMDDIDTDAVFTDMV--LRLAAGMERRTTHGGTAST---
Rv0681|M.tuberculosis_H37Rv MTG--------VMDDIDTDAVFTDMV--LRLAAGMERRTTHGGTAST---
MAV_4494|M.avium_104 MTG--------VMDDIDTDALFSDMV--LRLAAGLERRTAHG--------
MMAR_1010|M.marinum_M MTG--------LMEEIDTDAVFSDMV--LRLAAGMEKRISHTGAESL---
MUL_0762|M.ulcerans_Agy99 MTG--------LMEEIDTDAVFSDMV--LRLAAGMEKRISHTGAESL---
Mflv_5079|M.gilvum_PYR-GCK MTG--------VMNGIDTDAVFTDMV--MRLAAGMQTR------------
MAB_3216c|M.abscessus_ATCC_199 VSARGASLSS-VEDELPEKTLRSLSS--YPNLQRMQKQLSEDHSATEFEE
MSMEG_3332|M.smegmatis_MC2_155 LQEIVER-PE-ETDHVMRLGLHRLPIGEFPHVRDLAPTWAAYDGLAELDR
Mvan_1315|M.vanbaalenii_PYR-1 IEAADHHDTAPDYPALLRRLVTGERFPALAAALQAEAFDADGDRLADFRS
TH_0654|M.thermoresistible__bu QSR-----------------LQWDAAG-----AEVAEPPADDNPSARFAF
:
Mb0700|M.bovis_AF2122/97 ---------------------------
Rv0681|M.tuberculosis_H37Rv ---------------------------
MAV_4494|M.avium_104 ---------------------------
MMAR_1010|M.marinum_M ---------------------------
MUL_0762|M.ulcerans_Agy99 ---------------------------
Mflv_5079|M.gilvum_PYR-GCK ---------------------------
MAB_3216c|M.abscessus_ATCC_199 ALESLLDRLEN------GAPR------
MSMEG_3332|M.smegmatis_MC2_155 GLDILLTGLATRLDMPGGMPTRAPEPG
Mvan_1315|M.vanbaalenii_PYR-1 GLDQFLDGIDSRVRRSR----------
TH_0654|M.thermoresistible__bu GLNLLINGIAAEIDAAARKSE------