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MNKFRTQILDNLRARPADVVPAPGRPPLARFLYRFSIPILVLWLGAAGLLNLAVPQLETVIKQHARSFLP DDAASVQAISKMGDYFGGAGTNNFVYLLLEGESPLGAEAHQYYSSILDRINQDKKHVNSSMDLWSDPQFA PANESADGKAAYVLINLKGNMGTALAMESTAQIRELIAQYPPPKGITAHLTGPSAVVNDELVSINDSILI LLVACAGLVGVILLVVYRSPITIALPLLVAGAGLGVGRPIVAFLGQHQVIGVSIFASALLAVIVLGAGID YGIFLLGRYQEARRAGEDPVTAYYTALAGVQHIIIASGLTVAGATACMVFTRLAIFSTSGLPCTVAVVVT LGAALTLAPAALAAGSRFGFFEPREEKSQRRWRRIATYVVRWPGPVLAGSMAVLAIAFLAVPGFQPSYNE RQAQPSDSPANVGFAASDRHLPPNIMSPSVFIVESDHDMRNSGDLIALAKMSSAILNIPGISNVQGITRP LAAPLELGTLPAQAGYVGGRLTQMTNLLKQRIEDLTALSGRVGQLSLTVRGLEQAVRTGTTGATQIHSGA AELRTSLAAVVQKVDSLRGTAKPAEDFIGGIPNCRDNDYCQAALTGFSLFDDLHRFDGLVGNLVNGTGTL AQTLPALGAQLPGLKDFINQVNAVIAPLQSTLQVLLPQVSEITQFTDDLSKSFTDGDPNNSFFIPTQAFQ NPLFKSAMPYFFSGDGKVTRMVVTPEREGFSQEAMELSSKIIPTALQAIKGTSLAGSTVSIGGPGGTLLN IEAFTREDFITSAVAAFAFVFCVILILLRSLVAAIVVIGTVALSYVSALGVTVFVWQELIGIPLHWSVAP LSFVFLVAVGADYNMLLVARFREELHAGIKTGIIRSMANTGGVVTTAGLVFGFTMFAMIVAPARNIAQLG TAVGLGLLMDTLIVRSFVVPAIATLLGRWFWWPAVVHDRAASRDTVARAVTSADVTGPVRLVGASR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_3201 | - | - | 100% (976) | putative membrane protein MmpL |
| M. abscessus ATCC 19977 | MAB_2210c | - | 0.0 | 56.30% (936) | MmpL family protein |
| M. abscessus ATCC 19977 | MAB_3150 | - | 0.0 | 39.46% (920) | MmpL family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0458c | mmpL4 | 0.0 | 38.42% (950) | transmembrane transport protein MmpL4 |
| M. gilvum PYR-GCK | Mflv_4418 | - | 0.0 | 38.88% (944) | transport protein |
| M. tuberculosis H37Rv | Rv2339 | mmpL9 | 0.0 | 38.35% (944) | transmembrane transport protein MmpL9 |
| M. leprae Br4923 | MLBr_02378 | - | 0.0 | 38.59% (920) | hypothetical protein MLBr_02378 |
| M. marinum M | MMAR_1877 | mmpL5_1 | 0.0 | 39.48% (922) | transmembrane transport protein, MmpL5_1 |
| M. avium 104 | MAV_2510 | - | 0.0 | 38.32% (955) | MmpL4 protein |
| M. smegmatis MC2 155 | MSMEG_0381 | - | 0.0 | 39.17% (942) | Mmp14a protein |
| M. thermoresistible (build 8) | TH_3260 | - | 0.0 | 37.46% (929) | PUTATIVE MmpL4 protein |
| M. ulcerans Agy99 | MUL_3688 | mmpL4_1 | 0.0 | 38.92% (930) | transmembrane transport protein MmpL4_1 |
| M. vanbaalenii PYR-1 | Mvan_3833 | - | 0.0 | 38.89% (923) | transport protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0458c|M.bovis_AF2122/97 ------MSTKFANDSNTNARPEK----------------PFIARMIHAFA
MLBr_02378|M.leprae_Br4923 ------MTVKCANDLDTHTKP------------------PFVARMIHRFA
MMAR_1877|M.marinum_M ------MSGKYLN--NTDIEP------------------SILARSIYKFA
MSMEG_0381|M.smegmatis_MC2_155 -------MTEPATTQNREARP-------------------RIASFIRRFS
Mvan_3833|M.vanbaalenii_PYR-1 -------MRAHADRDLRDPTP--------------------VARWIRRLA
MAV_2510|M.avium_104 ----MSTTFDDTRTDAIPVVKEPVREK--------------IPRFIRAFA
TH_3260|M.thermoresistible__bu ----MTANPGHVRTDEAPTDRLDIKVSTH--------GPSFISTWIRRLS
Mflv_4418|M.gilvum_PYR-GCK -------MADAGRSG--------------------------IGRIIRVLA
Rv2339|M.tuberculosis_H37Rv ------MVPGEVHMSDTPSGPHP-----------------IIPRTIRLAA
MUL_3688|M.ulcerans_Agy99 ----MSESNSGASISTEDTGPIEIGAATGGAPNRERGHRPVIPHTIRILA
MAB_3201|M.abscessus_ATCC_1997 MNKFRTQILDNLRARPADVVPAPGR--------------PPLARFLYRFS
: : :
Mb0458c|M.bovis_AF2122/97 VPIILGWLAVCVVVTVFVPSLEAVGQERSVSLSPKDAPSFEAMGRIGMVF
MLBr_02378|M.leprae_Br4923 VPIILVWLAIAVTVSVFIPSLEDVGQERSVSLSPKDAPSYIAMQKMGQVF
MMAR_1877|M.marinum_M VPIALFWLAVCAIIAAFVPSLESVGENRSVSLTPRDAPAMQAIHRIGAVF
MSMEG_0381|M.smegmatis_MC2_155 VLIILAWIVVAALATFAIPPLEVVEREHSVSLSPPDAPSVQAMKRMGEVF
Mvan_3833|M.vanbaalenii_PYR-1 IPIILGWVLLVAALNLLVPQLEVVAAQNAVSMSPSDAPAMQAMSDMGRLF
MAV_2510|M.avium_104 VPIIIGWIALIAVLNVVVPQLDEVGKMRSVEMTPDDAQSVVATKRMGAVF
TH_3260|M.thermoresistible__bu LPIIVGWIALIALLNITVPQLEVVGEMRAVSMSPDEAPSMVAMKRVGELF
Mflv_4418|M.gilvum_PYR-GCK VPIVLGWVLLTVLTNVAVPSLEKVGEEHTVGMSAGDAPSMMSMKRVGANF
Rv2339|M.tuberculosis_H37Rv IPILLCWLGFTVFVSVAVPPLEAIGETRAVAVAPDDAQSMRAMRRAGKVF
MUL_3688|M.ulcerans_Agy99 VPIILGWVLLTVLVNVVVPSLEVVSEQHSAPMTPMDAPSMKAMMRLGHNF
MAB_3201|M.abscessus_ATCC_1997 IPILVLWLGAAGLLNLAVPQLETVIKQHARSFLPDDAASVQAISKMGDYF
: * : *: :* *: : .: . . :* : : * *
Mb0458c|M.bovis_AF2122/97 KEGDSDSFAMVIIEGNQPLGDAAHKYYDGLVAQLRADKKHVQSVQDLWGD
MLBr_02378|M.leprae_Br4923 NEGNSDSVIMIVLEGDKPLGDDAHRFYDGLIRKLRADK-HVQSVQDFWGD
MMAR_1877|M.marinum_M KESDSDSIVTIVLEGDQPLGTEAHKYYDDLVRRLRGDTRHVQHVQDFWGD
MSMEG_0381|M.smegmatis_MC2_155 QESNSNSVAVLVLEGQEPLGDDAHRYYDEIIRKLKDDPEHVQHVQDFWGD
Mvan_3833|M.vanbaalenii_PYR-1 GESDSDSIAMVVLEGEQPLGDDAHAYYDQLIEKLEAAPDHVRNIQDMWGD
MAV_2510|M.avium_104 NEYKSNSSVMIVLEGQQPLGADAHAYYDEIVRRLNADTKHVEHVQDMWSD
TH_3260|M.thermoresistible__bu DEGSSDSQVMIVLEGEEPLGADARAFYDELVKRLEADDAHVENVQDLWSD
Mflv_4418|M.gilvum_PYR-GCK EEFDSDSSAMVVLEGEQPLGDAAHRYYDQLIDELEADTANVQHIADFWGD
Rv2339|M.tuberculosis_H37Rv NEFDSNSIAMVVLESDQPLGEKAHRYYDHLVDTLVLDQSHIQHIQDFWRD
MUL_3688|M.ulcerans_Agy99 REFDSNSTVMIVLEGQHKLGDDAHQYYDSLIRQLRQDPEHIQHIQDFWGD
MAB_3201|M.abscessus_ATCC_1997 GGAGTNNFVYLLLEGESPLGAEAHQYYSSILDRINQDKKHVNSSMDLWSD
::. :::*.: ** *: :*. :: : ::. *:* *
Mb0458c|M.bovis_AF2122/97 PLTAAGVQSNDGKAAYVQLSLAGNQGTPLANESVEAVRSIVEST---PAP
MLBr_02378|M.leprae_Br4923 PLTAPGAQSNDGKAAYVQLSLAGNQGELLAQESIDAVRKIVVQT---PAP
MMAR_1877|M.marinum_M PLTASGSQSADDKAAYVQLNLAGNQGEPLGNESVEAVRSIVDGA---KPP
MSMEG_0381|M.smegmatis_MC2_155 PLTAGAAESGDRKAAYVQINLHGSFGQAEANESVKAVQDAVEST---PAP
Mvan_3833|M.vanbaalenii_PYR-1 PLTEAAAQSTDGHAAYVALNLAGNMGETKSNESVAAVRDIVADS---PPP
MAV_2510|M.avium_104 PLTGAGAQSNDGKASYVQVYLAGNQGEALANESVESVQNIVKSV---QAP
TH_3260|M.thermoresistible__bu PLTATGVQSPDGKSAYVQVKLAGNQGEALANESVETVREMIATVSEEMAP
Mflv_4418|M.gilvum_PYR-GCK PLTASGAQSTDGKAAYVQVYLQGNQGEPRANEAVAAVREIVDRT---PAP
Rv2339|M.tuberculosis_H37Rv PLTAAGAVSADGKAAYVQLYLAGNMGEALANESVEAVRKIVANS---TPP
MUL_3688|M.ulcerans_Agy99 RLTAAGAQSADGKSAYVMVNLAGNQGTTLANESVEAVRDVINRT---HEP
MAB_3201|M.abscessus_ATCC_1997 PQFAPANESADGKAAYVLINLKGNMGTALAMESTAQIRELIAQY---PPP
. * * :::** : * *. * . *: ::. : *
Mb0458c|M.bovis_AF2122/97 PGIKAYVTGPSALAADMHHSGDRSMARITMVTVAVIFIMLLLVYRSIITV
MLBr_02378|M.leprae_Br4923 PGITAWVTGASALIADMHHSGDKSMIRITATSVIVILVTLLLVYRSFITV
MMAR_1877|M.marinum_M PGIAVYVTGTAALVADMQHSGDRSLARITVTTAAVIFIMLLLVYRSPLTV
MSMEG_0381|M.smegmatis_MC2_155 PGVQAFVTGPAAIVADMGESGNKTVLLITLVTVGVIFLMLLLLYRRVLIV
Mvan_3833|M.vanbaalenii_PYR-1 PGVQVHVTGPAALTADVNIAGESSMALILLVTFVVIIVLLLFFYRSITTV
MAV_2510|M.avium_104 NGVKAYVTGPAALSADQHTAGDRSLQLITAATFTVIIGMLLLVYRSVITV
TH_3260|M.thermoresistible__bu EGVQAFVTGGAAMSADQQEAGDSSLRVIEALTFLVITTMLLFVYRSVITV
Mflv_4418|M.gilvum_PYR-GCK PGIKAYVTGGAPLVADQHSAGDTSVLRVTLITIGVIAVMLLIVFRSVATM
Rv2339|M.tuberculosis_H37Rv EGIRTYVTGPAALFADQIAAGDRSMKLITGLTFAVITVLLLLVYRSIATT
MUL_3688|M.ulcerans_Agy99 AGVKAYVTGPAALSDDMHLIGNASLATITMFTLGAIAVMLLLVYRSIVTT
MAB_3201|M.abscessus_ATCC_1997 KGITAHLTGPSAVVNDELVSINDSILILLVACAGLVGVILLVVYRSPITI
*: . :** :.: * : :: : : **..:*
Mb0458c|M.bovis_AF2122/97 VLLLITVGVELTAARGVVAVLGHSGAIGLTTFAVSLLTSLAIAAGTDYGI
MLBr_02378|M.leprae_Br4923 ILLLFTVGIESAVARGVVALLGHTGLIGLSTFAVNLLTSLAIAAGTDYGI
MMAR_1877|M.marinum_M VLLLLTVGAEFTVARGVVALLGQVGAIALSTFAVSLLTSLAIAAGTDYGI
MSMEG_0381|M.smegmatis_MC2_155 LILLATVAIELQVARGLVSFLALNGIVGLTTYVVNLLVSVGIAAGTDYGI
Mvan_3833|M.vanbaalenii_PYR-1 VLLLIMVGVQMSVARGVVAALGHFQVIGLSTFAVNLLISLAVAAGTDYAI
MAV_2510|M.avium_104 LLTLVMVVLELSAARGMVAFLGYYKIIGLSTFATNLLVTLAIAAATDYAI
TH_3260|M.thermoresistible__bu LIALFMVLIGLLTTRGVVAFLGYHNIIGLSTFATSLLVTLAIAIAVDYAI
Mflv_4418|M.gilvum_PYR-GCK VLILFMVFAELGAARGIVAFLADAEIIGLSTFATSLLTLMVIAAGTDYAI
Rv2339|M.tuberculosis_H37Rv LLILPMVFIGLGATRGTIAFLGYHGMVGLSTFVVNILTALAIAAGTDYAI
MUL_3688|M.ulcerans_Agy99 VIQLFMTGIALASSRGVVAVLGYHNVFGLTTFAANILTMLAIAAGTDYGI
MAB_3201|M.abscessus_ATCC_1997 ALPLLVAGAGLGVGRPIVAFLGQHQVIGVSIFASALLAVIVLGAGIDYGI
: * . * :: *. ..:: :. :* : :. . **.*
Mb0458c|M.bovis_AF2122/97 FIIGRYQEARQAGEDKEAAYYTMYRGTAHVILGSGLTITGATFCLSFARM
MLBr_02378|M.leprae_Br4923 FITGRYQEARQANENKEAAFYTMYRGTFHVILGSGLTISGATFCLSFARM
MMAR_1877|M.marinum_M FIIGRYQEARQAGEDRETAFYTMYRGVAHVIAGSGLTIAGATSCLSLARL
MSMEG_0381|M.smegmatis_MC2_155 FFAGRYQEARQAGEDREQAYYTSFAGVAKVVLASGATIAGAIACLSFTRL
Mvan_3833|M.vanbaalenii_PYR-1 FLVGRYQEARASGADPEAAYYEMFGGTAHVVLGSGLTIAGAMYCLSFARM
MAV_2510|M.avium_104 FLIGRYQEARAVGESREDAYYTMYKGTAHVVAGSGMTIAGATFCLHFTNL
TH_3260|M.thermoresistible__bu FLIGRYQEARSVGADRATAYHTMFGGTAHVILASGLTIAGATFCLSFTRL
Mflv_4418|M.gilvum_PYR-GCK FAIGRYQEARGAGEDRETAYYTMFRGTAHVVLGSGLTIAGAMLCLSFTRL
Rv2339|M.tuberculosis_H37Rv FLVGRYQEARHIGQNREASFYTMYRGTANVILGSGLTIAGATYCLSFARL
MUL_3688|M.ulcerans_Agy99 FLVGRYQEARQAGEDRQDAYYTTFRGVAPVVLGSGLTIAGATYCLSFARL
MAB_3201|M.abscessus_ATCC_1997 FLLGRYQEARRAGEDPVTAYYTALAGVQHIIIASGLTVAGATACMVFTRL
* ******* . . ::: *. :: .** *::** *: ::.:
Mb0458c|M.bovis_AF2122/97 PYFQTLGIPCAVGMLVAVAVALTLGPAVLHVGSRFG-LFDPKRLLKVRGW
MLBr_02378|M.leprae_Br4923 PYFQTLGVPCAVGMLIAVAVALTLGPAVLTVGSRFG-LFEPKRLIKVRGW
MMAR_1877|M.marinum_M PYFRTLGIPCAVGMLLAVVVALTLGPAVLAIGSRFG-VFDPKRMIKIRGW
MSMEG_0381|M.smegmatis_MC2_155 PYFQPLGIPGAVGIGVAVAVALTLVPACIAATNRFG-WFDPRRLVTTRRW
Mvan_3833|M.vanbaalenii_PYR-1 PYFQSMGVPCAVGILAGVAVALTLGPAIVTVGSRFG-LLEPKRAMRIRAW
MAV_2510|M.avium_104 PYFQTLGIPLAIGMVVVVAAALTLGPAVISVASRFRQTLEPRRTQRIRGW
TH_3260|M.thermoresistible__bu PYFQSLGPPLAIGMIVLIVTSLTMGPAIITVATRFG-LLEPKRAARVRFW
Mflv_4418|M.gilvum_PYR-GCK PYFQTMGVPCAVGTFVAVIAALTLGPAVIVIGSRFG-LFDPKRAISSRGW
Rv2339|M.tuberculosis_H37Rv TLFHTMGPPLAIGMLVSVAAALTLAPAIIAIAGRFG-LLDPKRRLKTRGW
MUL_3688|M.ulcerans_Agy99 PWFNTMGAPVAIGMLVVVLAGLTLGPAVVFVGSRFHPFESKRAANRGRLW
MAB_3201|M.abscessus_ATCC_1997 AIFSTSGLPCTVAVVVTLGAALTLAPAALAAGSRFG-FFEPREEKSQRRW
. * . * * ::. : ..**: ** : ** . : * *
Mb0458c|M.bovis_AF2122/97 RRVGTVVVRWPLPVLVATCAIALVGLLALPGYKTSYNDRDYLPDFIPANQ
MLBr_02378|M.leprae_Br4923 RRIGTVVVRWPLPILITTCAIAMVGLLALPGYRTNYKDRAYLPASIPANQ
MMAR_1877|M.marinum_M RRIGTVVVRWPGPVLAATIAIALIGLLALPAYTTSYNNRDYTPGFTPANQ
MSMEG_0381|M.smegmatis_MC2_155 RRIGTAVVRWPAPILIATIAVAVIGLLTLPGYNPSYSDQKYIPQDIPANQ
Mvan_3833|M.vanbaalenii_PYR-1 RRVGATVVRWPGPILVASLALALIGLAALPGYKTSYDDTRYIPESIPANA
MAV_2510|M.avium_104 RKVGTVVVRWPGPILVLTIGVALVGLLTLPGYRTNYNDRNYLPTDLPANE
TH_3260|M.thermoresistible__bu RKVGASVVRWPGPIMVTTVAVTLVGLLALPGYRTNYNDRNYLPASFPSNA
Mflv_4418|M.gilvum_PYR-GCK RRIGVSVVRWPGPVLAATLALALVGLVTLPGYKTNYDARDYLPEDIPANV
Rv2339|M.tuberculosis_H37Rv RRVGTAVVRWPGPILATSVALALVGLLALPGYRPGYNDRYYLRAGTPVNR
MUL_3688|M.ulcerans_Agy99 RRVGTAVVRWPAPILALSGAIVLVGMVALPGFKTSYNDRYYLPASAPSNL
MAB_3201|M.abscessus_ATCC_1997 RRIATYVVRWPGPVLAGSMAVLAIAFLAVPGFQPSYNERQAQPSDSPANV
*::.. ***** *:: : .: :.: ::*.: ..*. * *
Mb0458c|M.bovis_AF2122/97 GYAAADRHFSQARMK-PEILMIESDHDMRNPADFLVLDKLAKGIFRVPGI
MLBr_02378|M.leprae_Br4923 GFAAADRHFPQARMK-PEILMIESDHDMRNPADFLILDKLARGIFRVPGI
MMAR_1877|M.marinum_M GFAAADRHFSQSRMK-PEALLIESDHDLRNPADFLVLDKVAKEIFRIPGI
MSMEG_0381|M.smegmatis_MC2_155 GFAAAARHFPESKMTTPDILLVEADHDMRNSADLLVLNKLAKAVFAVPGV
Mvan_3833|M.vanbaalenii_PYR-1 GLQAATKYFSLSRMS-PEVLIVEADRDLRNSSDFLILDRLAKRVFNVEGV
MAV_2510|M.avium_104 GYAAADRHFSQARMN-PEVLMIESDHDLRNSADFLVIDKIAKTVFRVPGI
TH_3260|M.thermoresistible__bu GYEAAERHFDPARLN-PELLLIESDHDLRNPADFLVIEKIAKAVFQVEGI
Mflv_4418|M.gilvum_PYR-GCK GYAVADQHFGSARMN-PELLMVESDHDLRNPADFLVIDKIAKSVFRVPGV
Rv2339|M.tuberculosis_H37Rv GYAAADRHFGPARMN-PEMLLVESDQDMRNPAGMLVIDKIAKEVLHVSGV
MUL_3688|M.ulcerans_Agy99 GEAAADRHFSHARMN-PDMLMVEAEHDMRNPADMLVLDKVAKNVIRTVGI
MAB_3201|M.abscessus_ATCC_1997 GFAASDRHLPPNIMS-PSVFIVESDHDMRNSGDLIALAKMSSAILNIPGI
* .: ::: :. *. :::*:::*:**...:: : ::: :: *:
Mb0458c|M.bovis_AF2122/97 SRVQAITRPEGTTMDHTSIPFQISMQNAGQLQTIKYQRDRANDMLKQADE
MLBr_02378|M.leprae_Br4923 SRVQAITRPDGTAMDHTSIPFQISMQNAGQVQTMKYQKDRMNDLLRQAEN
MMAR_1877|M.marinum_M SRVQGITRPEGKPMDHTSIPFQISMQNASQMQNLNYQRDRMDDLLRQADA
MSMEG_0381|M.smegmatis_MC2_155 SNVQAITRPEGTPIEHTSIPFMLSMSNASQRLSLPFQQQRMEDLLKQADE
Mvan_3833|M.vanbaalenii_PYR-1 ARVQAPSRPDGAPIAHTSIPFLISMQGVGQQQNMKLMKDRIADMRVQADD
MAV_2510|M.avium_104 GRVQAITRPQGTPIEHTSIPFQISMQGVTQQMNQKYQQDQMADMLHQADM
TH_3260|M.thermoresistible__bu SRVQGITRPEGTPIEHSSIPFMISQQGTLQILNQQYMQDRMADMLVQADE
Mflv_4418|M.gilvum_PYR-GCK ARVQTITRPDGKPIKHTTIPFQMSMQGTTQRLNEKYLQDRMADMLVQADA
Rv2339|M.tuberculosis_H37Rv ERVQAITRPQGVPLEHASIPFQISMMGATQTMSLPYMRERMADMLTMSDE
MUL_3688|M.ulcerans_Agy99 AMIQDITRPLGIPIQHSSIPFQNSMQSQTMMQNMAFLKERMADMTKMADE
MAB_3201|M.abscessus_ATCC_1997 SNVQGITRPLAAPLELGTLPAQAGYVGGRLTQMTNLLKQRIEDLTALSGR
:* :** . .: ::* . . ::: *: :
Mb0458c|M.bovis_AF2122/97 MATTIAVLTRMHSLMAEMASTTHRMVGDTEEMKEITEELRDHVADFDDFW
MLBr_02378|M.leprae_Br4923 MAETIASMRRMHQLMALLTENTHHILNDTVEMQKTTSKLRDEIANFDDFW
MMAR_1877|M.marinum_M IGKSITVMKRMYDLMMQMSDTMHQTVIDTGQIKDVTDELRDHIADFDDFW
MSMEG_0381|M.smegmatis_MC2_155 LTKNIALMKHMYALMQEMVATTHSTVETTHEVQQTTKDLRDSIEDFQDFW
Mvan_3833|M.vanbaalenii_PYR-1 IGETIATMKTMYGLMTKFSNITTVMIDDMTEMRDTVHQIRDMVATFDDQF
MAV_2510|M.avium_104 MQTTIDSMEKMQSITVQMSNDMHVMVQKMHDMTIDINDLRNKMADFEDFF
TH_3260|M.thermoresistible__bu MQLMIDTMDKMIALMEEMVETTDNMVRDMDEMAAHVAEMRDSISEFDDFF
Mflv_4418|M.gilvum_PYR-GCK MQTNVDTMTRMQSLMGQMSATTHEMVLKTKKTEIDIIEVRDNLADFDDFF
Rv2339|M.tuberculosis_H37Rv MLVAINSMEQMLDLVQQLNDVTHEMAATTREIKATTSELRDHLADIDDFV
MUL_3688|M.ulcerans_Agy99 MQVLIDTTERMYAVMRELDTTTTDMARVTAETSTITDELRDHLAEFDDFW
MAB_3201|M.abscessus_ATCC_1997 VGQLSLTVRGLEQAVRTGTTGATQIHSGAAELRTSLAAVVQKVDSLRGTA
: : . : : : : .
Mb0458c|M.bovis_AF2122/97 RPIRSYFYWEKHCYGIPICWSFRSIFDALDGIDKLSEQIGVLLGDLREMD
MLBr_02378|M.leprae_Br4923 RPIRSYFYWERHCFNIPICWSFRSIFDALDGVDQIDERLNSIVGDIKNMD
MMAR_1877|M.marinum_M RPIRSYFYWDKHCNGVPMCWSLRSIFDALDGVDKISDELTDLLGDVKTMD
MSMEG_0381|M.smegmatis_MC2_155 RPIRNYLYWEPHCYDIPLCWSIRSLFDGLDGINEVTDKMGDLVEDLDHLD
Mvan_3833|M.vanbaalenii_PYR-1 RPIRNYFYWEPHCYNIPLCWSFRSLFDSMDGISVMTDTFDKAVANMDEMK
MAV_2510|M.avium_104 RPMRSYFYWEKHCYDIPVCWSLRSVFDALDGIDTMTDDIQSLLPIMDHLD
TH_3260|M.thermoresistible__bu RPIRNYFYWEPHCYNIPVCWAMRSVFDTLDGINTMTDDIQNMLPHMHRLN
Mflv_4418|M.gilvum_PYR-GCK RPVRNYFYWEPHCYDIPVCWTMRSVFDTLDGINPLTDDISELIPDLERLD
Rv2339|M.tuberculosis_H37Rv RPLRSYFYWEHHCFDIPLCSATRSLFDTLDGVDTLTDQLRALTDDMNKME
MUL_3688|M.ulcerans_Agy99 RPMRSYFYWEKHCFDVPICWSFRSLFDSLDGIDKLSEKFSELTEDIQRTA
MAB_3201|M.abscessus_ATCC_1997 KPAEDFIGGIPNCRDNDYCQAALTGFSLFDDLHRFDGLVGNLVNGTGTLA
:* ..:: :* . * : : *. :*.: . .
Mb0458c|M.bovis_AF2122/97 RLMPQMVAQIPPQIEAMENMRTMILTMHSTMTGIFDQMLEMSDNATAMGK
MLBr_02378|M.leprae_Br4923 LLMPQMLEQFPPMIESMESMRTIMLTMHSTMSGIFDQMNELSDNANTMGK
MMAR_1877|M.marinum_M RLMPLTAAQIPPQIEALETVRDIVLTMHSTMIGIYDQMDELSANSTAMGK
MSMEG_0381|M.smegmatis_MC2_155 TLMPQMLLQFPPMIAMLENSRSMILTMHSTMSGIFSQMDDSTDNATAMGK
Mvan_3833|M.vanbaalenii_PYR-1 ALLPQMLATFPPMIETMESMRQMMLTTYATMGGFYDQMDELTRDSTEMGK
MAV_2510|M.avium_104 TLMPQMVALMPSMIENMKAMKTTMLTMYSTQKGLQDQQNEAQKNSNAMGK
TH_3260|M.thermoresistible__bu DLMPQMLTLLPTTVATMKTMRSMLLTMQATNAGLQDQMAEMQENANAMGE
Mflv_4418|M.gilvum_PYR-GCK ELMPQLIALLPSQIETMRSMQAMMLRQYQTQKGQLDQNAAMSEDADAMGE
Rv2339|M.tuberculosis_H37Rv ALTPQFLALLPPMITTMKTMRTMMLTMRSTISGVQDQMADMQDHATAMGQ
MUL_3688|M.ulcerans_Agy99 GLTSQMLTLIPPMIATMKTTKALTLTMQSTFSAMLDQMDELSNTAIVMGQ
MAB_3201|M.abscessus_ATCC_1997 QTLPALGAQLPGLKDFINQVNAVIAPLQSTLQVLLPQVSEITQFTDDLSK
. :* :. . * * : :.:
Mb0458c|M.bovis_AF2122/97 AFDAAKNDDSFYLPPEVFKNKDFQRAMKSFLSSDGHAARFIILHRGDPQS
MLBr_02378|M.leprae_Br4923 AFDTAKNDDSFYLPPEVFKNTDFKRAMKSFLSSDGHAARFIILHRGDPAS
MMAR_1877|M.marinum_M AFDTANNDDSFYLPPEVFTNANFKRIMKLFLSPDGHAARFIILHRGDPDR
MSMEG_0381|M.smegmatis_MC2_155 AFDAARNDDSFYLPPDILENEDFKRVMKIFMSPDGKAARMLITQRGDPAT
Mvan_3833|M.vanbaalenii_PYR-1 AFDAAKNDDSFYLPPEVFENEDFKRAMESFFSPDGKTVRMLIAHRGNPTT
MAV_2510|M.avium_104 AFDASKNDDSFYLPPETFNNKEFKKGMKNFISPDGHAVRFIISHDGDPMT
TH_3260|M.thermoresistible__bu AFDQARNDDSFYLPPEAFDNPDFQRGLEQFLSPDGHAVRFIISHQGDPMT
Mflv_4418|M.gilvum_PYR-GCK AFDDSMNDDSFYLPPEAFDNDDFKRGMENFISPDGRSVRFIISHEGDPAT
Rv2339|M.tuberculosis_H37Rv AFDTAKSGDSFYLPPEAFDNAEFQQGMKLFLSPNGKAVRFVISHESDPAS
MUL_3688|M.ulcerans_Agy99 SFDASKNDDFFYLPPEAFDNPDFQTGLRMFLSPDGKSARFFITHQGDPMT
MAB_3201|M.abscessus_ATCC_1997 SFTDGDPNNSFFIPTQAFQNPLFKSAMPYFFSGDGKVTRMVVTPEREGFS
:* . .: *::*.: : * *: : *:* :*: .*:.: :
Mb0458c|M.bovis_AF2122/97 PEGIKSIDAIRTAAEESLKGTPLEDAKIYLAGTAAVFHDISEGAQWDLLI
MLBr_02378|M.leprae_Br4923 VAGIASINAIRTAAEEALKGTPLEDTKIYLAGTAAVFKDIDEGANWDLVI
MMAR_1877|M.marinum_M PEGIARIDLIRTAAEESLKGSPLEDSRIYLTGTGAVSKDLSEGAKWDLLI
MSMEG_0381|M.smegmatis_MC2_155 PEGIALVEPIRVAAEEALKGTPLESAELHLAGTAAGVKDLVDGSKIDLLI
Mvan_3833|M.vanbaalenii_PYR-1 DEALQRVEPIKIAAIEALKGTPLENAQIQLGGTAATFKDMSDGSRYDLLI
MAV_2510|M.avium_104 QEGISHIGAIKKAAYEALKGTPLEGSKIYLAGTASIYKDLSDGNNYDLLI
TH_3260|M.thermoresistible__bu PEGLAKIEPIKKAAVEAIKGTPLEGSRVYLGGTAAVFKDMSDGTKYDLII
Mflv_4418|M.gilvum_PYR-GCK VEGISEVVPIKTAAKEAIKGTPLEGSTVYLAGTAATYKDMSDGAFYDLLI
Rv2339|M.tuberculosis_H37Rv TEGIDRIEAIRAATKDAIKATPLQGAKIYIGGTAATYQDIRDGTKYDILI
MUL_3688|M.ulcerans_Agy99 PEGISRVDAERTAAQEGLKQSSLSDAKVYLGGTAATFKDMADGEKYDLMI
MAB_3201|M.abscessus_ATCC_1997 QEAMELSSKIIPTALQAIKGTSLAGSTVSIGGPGGTLLNIEAFTREDFIT
.: :: :.:* :.* .: : : *... :: *::
Mb0458c|M.bovis_AF2122/97 AAISSLCLIFIIMLIITRAFIAAAVIVGTVALSLGASFGLSVLLWQHILA
MLBr_02378|M.leprae_Br4923 AGISSLCLIFIIMLIITRAFVAAAVIVGTVALSLGASFGLSVLLWQHILG
MMAR_1877|M.marinum_M AGIASLCLIFIIMLILTRALIAATVIVGTVALSLGASFGLSVLVWQHIFG
MSMEG_0381|M.smegmatis_MC2_155 AGVAALCLIFIIMLIMTRSFIAALVIVGTVAMSLGASFGLSVLVWQHLLG
Mvan_3833|M.vanbaalenii_PYR-1 AVISALCLVLMIMLVLTRSLVAALVIVGTVTLSLGASFGISILIWQHIVG
MAV_2510|M.avium_104 AGISSLCLIFIIMLIITRGVVASAVIVGTVLLSLGASFGLSVLIWQHLIG
TH_3260|M.thermoresistible__bu AAIAAVCLIFIIMLILTRAVVAAAVIVGTVTLSLAASFGVSVLIWQYIVG
Mflv_4418|M.gilvum_PYR-GCK AGIAAVTLIFVIMLVITRSVVAAAVIVGTVLLSLGASFGLSVLLWQHIIG
Rv2339|M.tuberculosis_H37Rv VGIAAVCLVFIVMLMITQSLIASLVIVGTVLLSLGTAFGLSVLIWQHFVG
MUL_3688|M.ulcerans_Agy99 AVVSALTLIFLIMLLLTRSVVAALVIVGTAASSIAASFGLSVLIWQDLFG
MAB_3201|M.abscessus_ATCC_1997 SAVAAFAFVFCVILILLRSLVAAIVVIGTVALSYVSALGVTVFVWQELIG
:::. ::: ::*:: :..:*: *::**. * :::*:::::** :..
Mb0458c|M.bovis_AF2122/97 IHLHWLVLAMSVIVLLAVGSDYNLLLVSRFKQEIGAGLKTGIIRSMGGTG
MLBr_02378|M.leprae_Br4923 IELHYLVLAMSVIVLLAVGSDYNLLLVSRFKQEIQAGLKTGIIRSMGGTG
MMAR_1877|M.marinum_M IKLHWLVLPMSVIVLLAVGSDYNLLLVSRFKQEIGAGLNTGIIRAIGGTG
MSMEG_0381|M.smegmatis_MC2_155 IQINWVVLAMSVIVLLAVGSDYNLLLVSRMKEEIGAGLNTGIIRAMGGTG
Mvan_3833|M.vanbaalenii_PYR-1 IELHWMVLALSIIALIAVGSDYNLLLVSRFKEEIPAGIKTGIIRAIGGTG
MAV_2510|M.avium_104 IELHWMVLAMSVIILLAVGADYNLLLVARFKEEIHAGLNTGIIRSMGGTG
TH_3260|M.thermoresistible__bu LEMHWMVFPMALIILLAVGADYNLLVVARLREEIPAGLNTGMIRAMGGSG
Mflv_4418|M.gilvum_PYR-GCK LALHWMVLPMAVILLLAVGSDYNLLLVSRFKEELSGGLKTGIIRAMAGTG
Rv2339|M.tuberculosis_H37Rv LQVHWTIVAMSVIVLLAVGSDYNLLLVSRFKEEVGAGLKTGIIRAMAGTG
MUL_3688|M.ulcerans_Agy99 IKIHWIVAALSVIILLAVGSDYNLLLVSRFREEIHAGLKTGIIRSMAGTG
MAB_3201|M.abscessus_ATCC_1997 IPLHWSVAPLSFVFLVAVGADYNMLLVARFREELHAGIKTGIIRSMANTG
: ::: : .::.: *:***:***:*:*:*:::*: .*::**:**::..:*
Mb0458c|M.bovis_AF2122/97 KVVTNAGLVFAVTMASMAVSDLRVIGQVGTTIGLGLLFDTLIVRSFMTPS
MLBr_02378|M.leprae_Br4923 KVVTNAGLVFAFTMASMVVSDLRVIGQVGTTIGLGLLFDTLIVRSFMMPS
MMAR_1877|M.marinum_M KVVTNAGLVFAITMASMIVSDLRIIGQVGTTISLGLLFDTLIVRAFMTPS
MSMEG_0381|M.smegmatis_MC2_155 KVVTAAGLVFAATMASMIVSDLLTIGQVGTTIGLGLLFDTLVVRAFMTPS
Mvan_3833|M.vanbaalenii_PYR-1 SVVTVAGVVFALTMASMVVSDLRVMAQVGTTIGLGLLFDTFIVRAFMMPA
MAV_2510|M.avium_104 SVVTSAGLVFAFTMMTMAVSELTVIGQVGTTIGLGLLFDTLIVRSLMTPS
TH_3260|M.thermoresistible__bu SVVTAAGLVFGLTMMVMVVSDLTVMGQVGTTIGLGLLFDTFVVRSFMMPS
Mflv_4418|M.gilvum_PYR-GCK SVVTSAGLVFAFTMASFAFSDLKVMAQVGTTIALGLLFDTLIVRSFMTPA
Rv2339|M.tuberculosis_H37Rv AVVTSAGLVFAFTMASMAVSELRVIGQVGTTIGLGLLFDTLVVRSFMTPS
MUL_3688|M.ulcerans_Agy99 GVVTAAGLVFAFTMASMLGSDLRVLGQFGSTVCIGLLLDTLIVRTLLMPS
MAB_3201|M.abscessus_ATCC_1997 GVVTTAGLVFGFTMFAMIVAPARNIAQLGTAVGLGLLMDTLIVRSFVVPA
*** **:**. ** : : :.*.*::: :***:**::**::: *:
Mb0458c|M.bovis_AF2122/97 IAALLGRWFWWPLRVRSRPARTPTVPSETQPAG-------------RPLA
MLBr_02378|M.leprae_Br4923 IAALLGRWFWWPQQGRTRPLLTVAAPVGLPPD--------------RSLV
MMAR_1877|M.marinum_M IAALLGRWFWWPLQVRTRPTRPTAVKPRRPDPPDHLPSVGERHQTRRLRA
MSMEG_0381|M.smegmatis_MC2_155 IAALLGRWFWWPQRVRQRPASAMLRSVGPRPLV-------------RSLL
Mvan_3833|M.vanbaalenii_PYR-1 IATLLGRWFWWPLVVRSRPLRLPPRT------------------------
MAV_2510|M.avium_104 IAALLGKWFWWPQRVRQRP-VPSPWPKPAAQEREVLADA-----------
TH_3260|M.thermoresistible__bu IATLLGRWFWWPQFVRKRP-VPQPWPSVPPRGPATTDRVSV---------
Mflv_4418|M.gilvum_PYR-GCK VAALLGRWFWWPQKFRSAA-SERRLARIG-VQPATAGR------------
Rv2339|M.tuberculosis_H37Rv IAALLGRWFWWPNMIHSRPTVPEAHTRQGARRIQPHLHRG----------
MUL_3688|M.ulcerans_Agy99 IATLLGRWFWWPQVVHPRG--DNARPRVAAPTH-----------------
MAB_3201|M.abscessus_ATCC_1997 IATLLGRWFWWPAVVHDRAASRDTVARAVTSADVTGPVRLVGASR-----
:*:***:***** :
Mb0458c|M.bovis_AF2122/97 MSSDRLG--
MLBr_02378|M.leprae_Br4923 YSD------
MMAR_1877|M.marinum_M LSTETLSPG
MSMEG_0381|M.smegmatis_MC2_155 LRD------
Mvan_3833|M.vanbaalenii_PYR-1 ---------
MAV_2510|M.avium_104 ---------
TH_3260|M.thermoresistible__bu ---------
Mflv_4418|M.gilvum_PYR-GCK ---------
Rv2339|M.tuberculosis_H37Rv ---------
MUL_3688|M.ulcerans_Agy99 ---------
MAB_3201|M.abscessus_ATCC_1997 ---------