For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
SGSHANGEPTFVAKWIRRLSVPIVVGWVALVVILALAAPQLEQVGQENAVSLSPSDAPSMKAMKNMGRLF QESDSNSVTMIVLEGDQPLGPGAHKFYDEMVSQLRADTKHVQHVQDFWGDPLTESGAQSTDGKATYVQVN LSGDMGETLANESIEAVRDIVKKLTTDEHGNPKAMPDGLKVYVTGAAALQADMGHAGDSSMLKITGLTFI VIIIMLLFFYRSIFTVLMVLLMVGIQLGAARGMISVLGDNHIIGLSTFAVNLLVVLVIAAGTDYAIFLIG RYQEARVNGLDREAAYYEMFHGTAHVILGTGSTIAGAMYCLSFTRMPYFQTLGVPCAVAVLTAVAVALTV GPSLITIGSKFGLFEPKRAMRIRTWRRIGAAITRWPGPILAASMAIAIIGLAALPGYKTSYDDKKYIPKD IPANQGFQAADRHFDPARMNPEMLILESDHDMRNSADFLVIDKLAKAVYRVPGIARVQAITRPQGTPIEH SSIPFLISAQGVGQVQNLKLMKDRMADMKVQADQMGVMVTTMKKMLANMTELTGVMHQMIVDMHTLQGTI HDMRDSLENFDDWFRPIKNYFYWEKHCFDIPVCQAFRSIFEVLDKIDELTENMDGMIVSMEQMDVIMPKM VEDMRDMIPLMESMQNMMLTMHSTMAGMYDLQDETSKDSTAMGRAFDKAKNDDSFYLPPEIFDNPDFKRG LKMFLSPDGKTLRMIISHRGDPTSPEGLSHIEPIKLAAIEAVKGTPLEDAKIELGGTAATFHDMADGARY DLMIAGISALCLIFLIMLLITRSFVASLVIVGTVLLSLGASFGLSVIIWQYILGKELHWMVMQMAIIVLL AVGSDYNLLLVSRLKEELPGGLKTGMIRAMGGTGSVVTSAGLVFAFTMMAMAISDLTIIGQVGTTIGLGL LFDTLVVRSFMTPAIATILGRWFWWPLNVRTRPLPPPRTPQPDTTPPPPAPAPVGAGPDPATTEFPRASY *
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_1134c | - | - | 100% (981) | membrane protein MmpL |
| M. abscessus ATCC 19977 | MAB_2301 | - | 0.0 | 79.15% (983) | putative membrane protein, mmpL |
| M. abscessus ATCC 19977 | MAB_3150 | - | 0.0 | 58.34% (941) | MmpL family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0458c | mmpL4 | 0.0 | 59.86% (969) | transmembrane transport protein MmpL4 |
| M. gilvum PYR-GCK | Mflv_2705 | - | 0.0 | 62.91% (941) | transport protein |
| M. tuberculosis H37Rv | Rv0450c | mmpL4 | 0.0 | 59.96% (969) | transmembrane transport protein MmpL4 |
| M. leprae Br4923 | MLBr_02378 | - | 0.0 | 60.08% (962) | hypothetical protein MLBr_02378 |
| M. marinum M | MMAR_3174 | mmpL4_5 | 0.0 | 62.46% (943) | transmembrane transport protein MmpL4_5 |
| M. avium 104 | MAV_2510 | - | 0.0 | 60.51% (942) | MmpL4 protein |
| M. smegmatis MC2 155 | MSMEG_0225 | - | 0.0 | 63.37% (950) | MmpL4 protein |
| M. thermoresistible (build 8) | TH_3260 | - | 0.0 | 59.43% (954) | PUTATIVE MmpL4 protein |
| M. ulcerans Agy99 | MUL_0757 | mmpL5 | 0.0 | 61.33% (949) | transmembrane transport protein, MmpL5 |
| M. vanbaalenii PYR-1 | Mvan_3833 | - | 0.0 | 64.05% (943) | transport protein |
CLUSTAL 2.0.9 multiple sequence alignment
MAV_2510|M.avium_104 MSTTFDDTRTDAIP------VVKEPVREKIPRFIRAFAVPIIIGWIALIA
MUL_0757|M.ulcerans_Agy99 MTATTTDTPTDVVP------PAEHPPRPFIPRMIRTFAVPLILGWVLLIA
MSMEG_0225|M.smegmatis_MC2_155 -MSTP-DAPTEAIPSAHG--KYTNHGG--IAKLIRTLAVPIILVWVALIA
TH_3260|M.thermoresistible__bu MTANPGHVRTDEAPTDRLDIKVSTHGPSFISTWIRRLSLPIIVGWIALIA
Mb0458c|M.bovis_AF2122/97 MSTKFANDSN----------TNARPEKPFIARMIHAFAVPIILGWLAVCV
Rv0450c|M.tuberculosis_H37Rv MSTKFANDSN----------TNARPEKPFIARMIHAFAVPIILGWLAVCV
MLBr_02378|M.leprae_Br4923 MTVKCANDLD----------THTKP--PFVARMIHRFAVPIILVWLAIAV
Mflv_2705|M.gilvum_PYR-GCK ----MSSSRDRA----------ALREPRSVARWIRRLAVPIILGWLLLAV
Mvan_3833|M.vanbaalenii_PYR-1 ----MRAHADR-----------DLRDPTPVARWIRRLAIPIILGWVLLVA
MMAR_3174|M.marinum_M MITRVFRPSSRE----------VRTEPALLARWIRRLAIPIMLGWLAIIV
MAB_1134c|M.abscessus_ATCC_199 -------MSGSH----------ANGEPTFVAKWIRRLSVPIVVGWVALVV
:. *: :::*::: *: : .
MAV_2510|M.avium_104 VLNVVVPQLDEVGKMRSVEMTPDDAQSVVATKRMGAVFNEYKSNSSVMIV
MUL_0757|M.ulcerans_Agy99 VLNSVVPQLEVVGQMQAVSMSPDAAPSMISMKHIGKVFREGDSDSAAMIV
MSMEG_0225|M.smegmatis_MC2_155 VLNTIVPQLEEVGEMRSVSMSPDDAPSMIAMKRVGEVFEEFKSNSSVMIV
TH_3260|M.thermoresistible__bu LLNITVPQLEVVGEMRAVSMSPDEAPSMVAMKRVGELFDEGSSDSQVMIV
Mb0458c|M.bovis_AF2122/97 VVTVFVPSLEAVGQERSVSLSPKDAPSFEAMGRIGMVFKEGDSDSFAMVI
Rv0450c|M.tuberculosis_H37Rv VVTVFVPSLEAVGQERSVSLSPKDAPSFEAMGRIGMVFKEGDSDSFAMVI
MLBr_02378|M.leprae_Br4923 TVSVFIPSLEDVGQERSVSLSPKDAPSYIAMQKMGQVFNEGNSDSVIMIV
Mflv_2705|M.gilvum_PYR-GCK ALNALVPQLEVVAAKNAVSMSPSNAPSMQAMADMGRLFEESDSDSIALIV
Mvan_3833|M.vanbaalenii_PYR-1 ALNLLVPQLEVVAAQNAVSMSPSDAPAMQAMSDMGRLFGESDSDSIAMVV
MMAR_3174|M.marinum_M LINILVPSLQQVAADNSVSMNPAGAPSLQAIKEMGRVFGESRSDSVALIL
MAB_1134c|M.abscessus_ATCC_199 ILALAAPQLEQVGQENAVSLSPSDAPSMKAMKNMGRLFQESDSNSVTMIV
: *.*: *. .:*.:.* * : : :* :* * *:* :::
MAV_2510|M.avium_104 LEGQ--QPLGADAHAYYDEIVRRLNADTKHVEHVQDMWSDPLTGAGAQSN
MUL_0757|M.ulcerans_Agy99 LEGQ--EPLGAAAHKFYDKMITKLRADTKHVQSVQDFWGDPLTATGAQSG
MSMEG_0225|M.smegmatis_MC2_155 LEGE--QPLGDEAHKYYDEIVDKLEADKTHIEHVQDFWGDPLTASGAQSS
TH_3260|M.thermoresistible__bu LEGE--EPLGADARAFYDELVKRLEADDAHVENVQDLWSDPLTATGVQSP
Mb0458c|M.bovis_AF2122/97 IEGN--QPLGDAAHKYYDGLVAQLRADKKHVQSVQDLWGDPLTAAGVQSN
Rv0450c|M.tuberculosis_H37Rv IEGN--QPLGDAAHKYYDGLVAQLRADKKHVQSVQDLWGDPLTAAGVQSN
MLBr_02378|M.leprae_Br4923 LEGD--KPLGDDAHRFYDGLIRKLRADK-HVQSVQDFWGDPLTAPGAQSN
Mflv_2705|M.gilvum_PYR-GCK LESETDQPLGDDAHEYYDGLIAALLADTENVRNIQDTWGDPLTEAAAQSS
Mvan_3833|M.vanbaalenii_PYR-1 LEGE--QPLGDDAHAYYDQLIEKLEAAPDHVRNIQDMWGDPLTEAAAQST
MMAR_3174|M.marinum_M LEGR--QPLGADAHEYYDDLVTRLRADTAHVQNVQDFWGDPLTEGSAQSP
MAB_1134c|M.abscessus_ATCC_199 LEGD--QPLGPGAHKFYDEMVSQLRADTKHVQHVQDFWGDPLTESGAQST
:*. :*** *: :** :: * * ::. :** *.**** ..**
MAV_2510|M.avium_104 DGKASYVQVYLAGNQGEALANESVESVQNIVKSV---------QAPNGVK
MUL_0757|M.ulcerans_Agy99 DGKAAYVQVKLAGNQGESLANESVEAVKTIVDSL---------QAPPGVK
MSMEG_0225|M.smegmatis_MC2_155 DGLASYVQVYTAGNQGEALANESVKAVQDIVDSV---------QAPPGVT
TH_3260|M.thermoresistible__bu DGKSAYVQVKLAGNQGEALANESVETVREMIATVSEE------MAPEGVQ
Mb0458c|M.bovis_AF2122/97 DGKAAYVQLSLAGNQGTPLANESVEAVRSIVEST---------PAPPGIK
Rv0450c|M.tuberculosis_H37Rv DGKAAYVQLSLAGNQGTPLANESVEAVRSIVEST---------PAPPGIK
MLBr_02378|M.leprae_Br4923 DGKAAYVQLSLAGNQGELLAQESIDAVRKIVVQT---------PAPPGIT
Mflv_2705|M.gilvum_PYR-GCK DGRAAYATLNLAGNMGETESNEAVAAVRDIVANSPP---------PPGVT
Mvan_3833|M.vanbaalenii_PYR-1 DGHAAYVALNLAGNMGETKSNESVAAVRDIVADSPP---------PPGVQ
MMAR_3174|M.marinum_M DGKAAYLQLYLSGNIGDTLANESVGAVWAAVDARPP---------PPGVK
MAB_1134c|M.abscessus_ATCC_199 DGKATYVQVNLSGDMGETLANESIEAVRDIVKKLTTDEHGNPKAMPDGLK
** ::* : :*: * ::*:: :* : * *:
MAV_2510|M.avium_104 AYVTGPAALSADQHTAGDRSLQLITAATFTVIIGMLLLVYRSVITVLLTL
MUL_0757|M.ulcerans_Agy99 VYVTGSAALVADQQLAGDRSLQLIEMVTFTVIIVMLLLVYRSIITAAIML
MSMEG_0225|M.smegmatis_MC2_155 AYVTGPAAMSADQQIAGDRSMRMIEALTFTVIIIMLLMVYRSIITVILSL
TH_3260|M.thermoresistible__bu AFVTGGAAMSADQQEAGDSSLRVIEALTFLVITTMLLFVYRSVITVLIAL
Mb0458c|M.bovis_AF2122/97 AYVTGPSALAADMHHSGDRSMARITMVTVAVIFIMLLLVYRSIITVVLLL
Rv0450c|M.tuberculosis_H37Rv AYVTGPSALAADMHHSGDRSMARITMVTVAVIFIMLLLVYRSIITVVLLL
MLBr_02378|M.leprae_Br4923 AWVTGASALIADMHHSGDKSMIRITATSVIVILVTLLLVYRSFITVILLL
Mflv_2705|M.gilvum_PYR-GCK VHVTGPAALIADVNIAGERSMALVLLVTFVVIIVLLLFFYRSISTVLLLL
Mvan_3833|M.vanbaalenii_PYR-1 VHVTGPAALTADVNIAGESSMALILLVTFVVIIVLLLFFYRSITTVVLLL
MMAR_3174|M.marinum_M VYVTGPAALQADLIHSAERTVRTIKIATFTVIIVLMLFFFRSVPTVLVLL
MAB_1134c|M.abscessus_ATCC_199 VYVTGAAALQADMGHAGDSSMLKITGLTFIVIIIMLLFFYRSIFTVLMVL
. *** :*: ** :.: :: : :. ** :*:.:**. *. : *
MAV_2510|M.avium_104 VMVVLELSAARGMVAFLGYYKIIGLSTFATNLLVTLAIAAATDYAIFLIG
MUL_0757|M.ulcerans_Agy99 TMVVLGLLATRGGVAFLGYHRIIGLSTFATNLLVVLAIAAATDYAIFLIG
MSMEG_0225|M.smegmatis_MC2_155 VMVVFSLAAARGVIAFLGYYEIIGLSTFATNLLVTLAIAAATDYAIFLIG
TH_3260|M.thermoresistible__bu FMVLIGLLTTRGVVAFLGYHNIIGLSTFATSLLVTLAIAIAVDYAIFLIG
Mb0458c|M.bovis_AF2122/97 ITVGVELTAARGVVAVLGHSGAIGLTTFAVSLLTSLAIAAGTDYGIFIIG
Rv0450c|M.tuberculosis_H37Rv ITVGVELTAARGVVAVLGHSGAIGLTTFAVSLLTSLAIAAGTDYGIFIIG
MLBr_02378|M.leprae_Br4923 FTVGIESAVARGVVALLGHTGLIGLSTFAVNLLTSLAIAAGTDYGIFITG
Mflv_2705|M.gilvum_PYR-GCK VVVGIQLLVARGVVAALAHVGVIGLSTYATNLLISLAVAAGTDYAIFLVG
Mvan_3833|M.vanbaalenii_PYR-1 IMVGVQMSVARGVVAALGHFQVIGLSTFAVNLLISLAVAAGTDYAIFLVG
MMAR_3174|M.marinum_M GVVGIQLSAATGVAAVIGYLGVVELSTFAVNLVVAMAIATGTDYAIFLIG
MAB_1134c|M.abscessus_ATCC_199 LMVGIQLGAARGMISVLGDNHIIGLSTFAVNLLVVLVIAAGTDYAIFLIG
* . .: * : :. : *:*:*..*: :.:* ..**.**: *
MAV_2510|M.avium_104 RYQEARAVGESREDAYYTMYKGTAHVVAGSGMTIAGATFCLHFTNLPYFQ
MUL_0757|M.ulcerans_Agy99 RYQEARGLGQDRESAYYTMFGGTAHVVLGSGLTIAGATFCLSFTRLPYFQ
MSMEG_0225|M.smegmatis_MC2_155 RYQEARSVGESREQAYYTMFHSTAHVVLGSGMTIAGATLCLHFTRMPYFQ
TH_3260|M.thermoresistible__bu RYQEARSVGADRATAYHTMFGGTAHVILASGLTIAGATFCLSFTRLPYFQ
Mb0458c|M.bovis_AF2122/97 RYQEARQAGEDKEAAYYTMYRGTAHVILGSGLTITGATFCLSFARMPYFQ
Rv0450c|M.tuberculosis_H37Rv RYQEARQAGEDKEAAYYTMYRGTAHVILGSGLTIAGATFCLSFARMPYFQ
MLBr_02378|M.leprae_Br4923 RYQEARQANENKEAAFYTMYRGTFHVILGSGLTISGATFCLSFARMPYFQ
Mflv_2705|M.gilvum_PYR-GCK RYQEARASGADHEEAYYEMFHGTAHVVLGSGLTIAGAMLCLSFTRMPYFQ
Mvan_3833|M.vanbaalenii_PYR-1 RYQEARASGADPEAAYYEMFGGTAHVVLGSGLTIAGAMYCLSFARMPYFQ
MMAR_3174|M.marinum_M RYQEARAAGVDRESAYYEMWHGTAHVVLASGLTIAGAALCMSLTRMPYLQ
MAB_1134c|M.abscessus_ATCC_199 RYQEARVNGLDREAAYYEMFHGTAHVILGTGSTIAGAMYCLSFTRMPYFQ
****** . . *:: *: .* **: .:* **:** *: ::.:**:*
MAV_2510|M.avium_104 TLGIPLAIGMVVVVAAALTLGPAVISVASRFRQTLEPRRTQRIRGWRKVG
MUL_0757|M.ulcerans_Agy99 TLGVPLAIGMVIVVATALTLGPALIAVMSRFGKLLEPKRMARVRGWRKIG
MSMEG_0225|M.smegmatis_MC2_155 SLGIPLAIGMTVVVLTALAVGPAIITVASRFGKTLEPKRAMRTRGWRKVG
TH_3260|M.thermoresistible__bu SLGPPLAIGMIVLIVTSLTMGPAIITVATRFG-LLEPKRAARVRFWRKVG
Mb0458c|M.bovis_AF2122/97 TLGIPCAVGMLVAVAVALTLGPAVLHVGSRFG-LFDPKRLLKVRGWRRVG
Rv0450c|M.tuberculosis_H37Rv TLGIPCAVGMLVAVAVALTLGPAVLHVGSRFG-LFDPKRLLKVRGWRRVG
MLBr_02378|M.leprae_Br4923 TLGVPCAVGMLIAVAVALTLGPAVLTVGSRFG-LFEPKRLIKVRGWRRIG
Mflv_2705|M.gilvum_PYR-GCK SMGIPCAVGIAAGVAVALTLGPAIVTVGSRFN-LLEPKRAMRIRAWRRIG
Mvan_3833|M.vanbaalenii_PYR-1 SMGVPCAVGILAGVAVALTLGPAIVTVGSRFG-LLEPKRAMRIRAWRRVG
MMAR_3174|M.marinum_M SLGVPTAVAMLVALSVALTLGPAAVTVASRFG-LLEPKRAIRIRFWRRIG
MAB_1134c|M.abscessus_ATCC_199 TLGVPCAVAVLTAVAVALTVGPSLITIGSKFG-LFEPKRAMRIRTWRRIG
::* * *:.: : .:*::**: : : ::* ::*:* : * **::*
MAV_2510|M.avium_104 TVVVRWPGPILVLTIGVALVGLLTLPGYRTNYNDRNYLPTDLPANEGYAA
MUL_0757|M.ulcerans_Agy99 AAIVRWPGPILIGAVALALVGLLTLPGYKTNYNDRNYLPADLPANEGYSA
MSMEG_0225|M.smegmatis_MC2_155 AAVVRWPGPILVAAVGLSMIGLLALPGYRTNYNDRDYQPADLPANSGYAA
TH_3260|M.thermoresistible__bu ASVVRWPGPIMVTTVAVTLVGLLALPGYRTNYNDRNYLPASFPSNAGYEA
Mb0458c|M.bovis_AF2122/97 TVVVRWPLPVLVATCAIALVGLLALPGYKTSYNDRDYLPDFIPANQGYAA
Rv0450c|M.tuberculosis_H37Rv TVVVRWPLPVLVATCAIALVGLLALPGYKTSYNDRDYLPDFIPANQGYAA
MLBr_02378|M.leprae_Br4923 TVVVRWPLPILITTCAIAMVGLLALPGYRTNYKDRAYLPASIPANQGFAA
Mflv_2705|M.gilvum_PYR-GCK TMVVRWPGPILVASLALALVGLAALPGYQTSYDDTRYVPESIPANAGLQA
Mvan_3833|M.vanbaalenii_PYR-1 ATVVRWPGPILVASLALALIGLAALPGYKTSYDDTRYIPESIPANAGLQA
MMAR_3174|M.marinum_M TAVVRWPAPILLASLAAALVGLIALPFYQPSYNDRRYIPGDIEANAGYAA
MAB_1134c|M.abscessus_ATCC_199 AAITRWPGPILAASMAIAIIGLAALPGYKTSYDDKKYIPKDIPANQGFQA
: :.*** *:: : . :::** :** *:..*.* * * : :* * *
MAV_2510|M.avium_104 ADRHFSQARMNPEVLMIESDHDLRNSADFLVIDKIAKTVFRVPGIGRVQA
MUL_0757|M.ulcerans_Agy99 AERHFSQARMNPEVLMVESDHDMRNSSDFLVINKIAKAIFGVEGISRVQA
MSMEG_0225|M.smegmatis_MC2_155 ADRHFSQARMNPELLMIESDHDLRNSADFLVIERIAKRVVGVPGVSRVQA
TH_3260|M.thermoresistible__bu AERHFDPARLNPELLLIESDHDLRNPADFLVIEKIAKAVFQVEGISRVQG
Mb0458c|M.bovis_AF2122/97 ADRHFSQARMKPEILMIESDHDMRNPADFLVLDKLAKGIFRVPGISRVQA
Rv0450c|M.tuberculosis_H37Rv ADRHFSQARMKPEILMIESDHDMRNPADFLVLDKLAKGIFRVPGISRVQA
MLBr_02378|M.leprae_Br4923 ADRHFPQARMKPEILMIESDHDMRNPADFLILDKLARGIFRVPGISRVQA
Mflv_2705|M.gilvum_PYR-GCK ATQHFTLSRMSPEILIVEADRDLRNPADFLVLDRLAKRVFAVEGVARVQA
Mvan_3833|M.vanbaalenii_PYR-1 ATKYFSLSRMSPEVLIVEADRDLRNSSDFLILDRLAKRVFNVEGVARVQA
MMAR_3174|M.marinum_M AEQHFSAARMNPEVLLVEADHDLRNPADFLVIDKLAKAIFRVPGVARVQA
MAB_1134c|M.abscessus_ATCC_199 ADRHFDPARMNPEMLILESDHDMRNSADFLVIDKLAKAVYRVPGIARVQA
* ::* :*:.**:*::*:*:*:**.:***:::::*: : * *:.***.
MAV_2510|M.avium_104 ITRPQGTPIEHTSIPFQISMQGVTQQMNQKYQQDQMADMLHQADMMQTTI
MUL_0757|M.ulcerans_Agy99 ITRPDGKPIEHTSIPFLISMQGTSQKLTEKYNQDLTTSMLQQVNDIQTNI
MSMEG_0225|M.smegmatis_MC2_155 ITRPQGTPIEHTSIPFTISMQGTTQTMNQKYMQDRMADMLVQADQMQVTV
TH_3260|M.thermoresistible__bu ITRPEGTPIEHSSIPFMISQQGTLQILNQQYMQDRMADMLVQADEMQLMI
Mb0458c|M.bovis_AF2122/97 ITRPEGTTMDHTSIPFQISMQNAGQLQTIKYQRDRANDMLKQADEMATTI
Rv0450c|M.tuberculosis_H37Rv ITRPEGTTMDHTSIPFQISMQNAGQLQTIKYQRDRANDMLKQADEMATTI
MLBr_02378|M.leprae_Br4923 ITRPDGTAMDHTSIPFQISMQNAGQVQTMKYQKDRMNDLLRQAENMAETI
Mflv_2705|M.gilvum_PYR-GCK PSRPDGSPIAKTSIPFLISMQGVGQQQNMKLMQDRMDDMRTQADNLGKTL
Mvan_3833|M.vanbaalenii_PYR-1 PSRPDGAPIAHTSIPFLISMQGVGQQQNMKLMKDRIADMRVQADDIGETI
MMAR_3174|M.marinum_M ITRPDGAPIQHTSIPFMMSMQGVGLQQNMKLMFDRIDDMKAQAESLGNTV
MAB_1134c|M.abscessus_ATCC_199 ITRPQGTPIEHSSIPFLISAQGVGQVQNLKLMKDRMADMKVQADQMGVMV
:**:* .: ::**** :* *.. . : * .: *.: : :
MAV_2510|M.avium_104 DSMEKMQSITVQMSNDMHVMVQKMHDMTIDINDLRNKMADFEDFFRPMRS
MUL_0757|M.ulcerans_Agy99 DQMERMHDLTQQMADVTHQMVIQMKGMVVDVEELRNHIADFDDFFRPIRS
MSMEG_0225|M.smegmatis_MC2_155 DTMTKMIALMEQMRDTMNSMVGKMHGMVDDIKELRDNISDFDDFFRPIRN
TH_3260|M.thermoresistible__bu DTMDKMIALMEEMVETTDNMVRDMDEMAAHVAEMRDSISEFDDFFRPIRN
Mb0458c|M.bovis_AF2122/97 AVLTRMHSLMAEMASTTHRMVGDTEEMKEITEELRDHVADFDDFWRPIRS
Rv0450c|M.tuberculosis_H37Rv AVLTRMHSLMAEMASTTHRMVGDTEEMKEITEELRDHVADFDDFWRPIRS
MLBr_02378|M.leprae_Br4923 ASMRRMHQLMALLTENTHHILNDTVEMQKTTSKLRDEIANFDDFWRPIRS
Mflv_2705|M.gilvum_PYR-GCK GTMRTMYGLMTRLSEVTTVMIDDFTEMQQTVHQIRDMVANFDDQFRPVRN
Mvan_3833|M.vanbaalenii_PYR-1 ATMKTMYGLMTKFSNITTVMIDDMTEMRDTVHQIRDMVATFDDQFRPIRN
MMAR_3174|M.marinum_M AIMKRMQASMSRMAGVGDGLVVDMDDMQTAVRDARDSLADFEDFFRPIRN
MAB_1134c|M.abscessus_ATCC_199 TTMKKMLANMTELTGVMHQMIVDMHTLQGTIHDMRDSLENFDDWFRPIKN
: * : :: . : . *: : *:* :**::.
MAV_2510|M.avium_104 YFYWEKHCYDIPVCWSLRSVFDALDGIDTMTDDIQSLLPIMDHLDTLMPQ
MUL_0757|M.ulcerans_Agy99 YFYWEKHCFDIPVCWSLRSVFDTLDGVDLMTEDINNLLPLMERLDTLMPQ
MSMEG_0225|M.smegmatis_MC2_155 YLYWEPHCYNIPMCYSLRSIFDTMDGIDTMTADFEQIVPDMDRMNALIPV
TH_3260|M.thermoresistible__bu YFYWEPHCYNIPVCWAMRSVFDTLDGINTMTDDIQNMLPHMHRLNDLMPQ
Mb0458c|M.bovis_AF2122/97 YFYWEKHCYGIPICWSFRSIFDALDGIDKLSEQIGVLLGDLREMDRLMPQ
Rv0450c|M.tuberculosis_H37Rv YFYWEKHCYGIPICWSFRSIFDALDGIDKLSEQIGVLLGDLREMDRLMPQ
MLBr_02378|M.leprae_Br4923 YFYWERHCFNIPICWSFRSIFDALDGVDQIDERLNSIVGDIKNMDLLMPQ
Mflv_2705|M.gilvum_PYR-GCK YFYWEPHCYNIPLCWSFRSLFDSMDGISTMTESFDKALVNMETMRSLLPQ
Mvan_3833|M.vanbaalenii_PYR-1 YFYWEPHCYNIPLCWSFRSLFDSMDGISVMTDTFDKAVANMDEMKALLPQ
MMAR_3174|M.marinum_M YFHWEPHCFDIPVCWALRSVSDSVDGIDAMTDQMDRMIKGMTDLNALIPE
MAB_1134c|M.abscessus_ATCC_199 YFYWEKHCFDIPVCQAFRSIFEVLDKIDELTENMDGMIVSMEQMDVIMPK
*::** **:.**:* ::**: : :* :. : : : : : ::*
MAV_2510|M.avium_104 MVALMPSMIENMKAMKTTMLTMYSTQKGLQDQQNEAQKNSNAMGKAFDAS
MUL_0757|M.ulcerans_Agy99 MTAMMPEMIQTMKSMKAQMLSMHSTQQGLQDQMAAMQEDSSAMGEAFDSS
MSMEG_0225|M.smegmatis_MC2_155 MIANMEPMITTMKTMKTMMLTMQATNAGLQDQMAAMQENSTAMGEAFDKA
TH_3260|M.thermoresistible__bu MLTLLPTTVATMKTMRSMLLTMQATNAGLQDQMAEMQENANAMGEAFDQA
Mb0458c|M.bovis_AF2122/97 MVAQIPPQIEAMENMRTMILTMHSTMTGIFDQMLEMSDNATAMGKAFDAA
Rv0450c|M.tuberculosis_H37Rv MVAQIPPQIEAMENMRTMILTMHSTMTGIFDQMLEMSDNATAMGKAFDAA
MLBr_02378|M.leprae_Br4923 MLEQFPPMIESMESMRTIMLTMHSTMSGIFDQMNELSDNANTMGKAFDTA
Mflv_2705|M.gilvum_PYR-GCK MLATFPPMIETMESMRQMMLTTYATMGGFYDQMDELTQDSTEMGKAFDEA
Mvan_3833|M.vanbaalenii_PYR-1 MLATFPPMIETMESMRQMMLTTYATMGGFYDQMDELTRDSTEMGKAFDAA
MMAR_3174|M.marinum_M MIAQFPPMIATMESMQQMMLTMHSTMSGMYRQMDELSHGAAEMGKAFDAA
MAB_1134c|M.abscessus_ATCC_199 MVEDMRDMIPLMESMQNMMLTMHSTMAGMYDLQDETSKDSTAMGRAFDKA
* : : *: *: :*: :* *: .: **.*** :
MAV_2510|M.avium_104 KNDDSFYLPPETFNNKEFKKGMKNFISPDGHAVRFIISHDGDPMTQEGIS
MUL_0757|M.ulcerans_Agy99 RNDDSFYLPPEVFNNPDFKRGLEQFLSPDGHAVRFIISHEGDPMSQAGIN
MSMEG_0225|M.smegmatis_MC2_155 KNDDSFYLPPETFDNPDFKRGMKMFLSPDGHAVRFIISHEGDPMSPEGIQ
TH_3260|M.thermoresistible__bu RNDDSFYLPPEAFDNPDFQRGLEQFLSPDGHAVRFIISHQGDPMTPEGLA
Mb0458c|M.bovis_AF2122/97 KNDDSFYLPPEVFKNKDFQRAMKSFLSSDGHAARFIILHRGDPQSPEGIK
Rv0450c|M.tuberculosis_H37Rv KNDDSFYLPPEVFKNKDFQRAMKSFLSSDGHAARFIILHRGDPQSPEGIK
MLBr_02378|M.leprae_Br4923 KNDDSFYLPPEVFKNTDFKRAMKSFLSSDGHAARFIILHRGDPASVAGIA
Mflv_2705|M.gilvum_PYR-GCK KNDDSFYLPPEVFENEDFKRAMESFFSPDGKTVRMLVSHRGDPTTPEALA
Mvan_3833|M.vanbaalenii_PYR-1 KNDDSFYLPPEVFENEDFKRAMESFFSPDGKTVRMLIAHRGNPTTDEALQ
MMAR_3174|M.marinum_M RNDDSFYLPSEVFDNPDFRRAMDLFISPDGKSLRMIISHRGDPASAEGIS
MAB_1134c|M.abscessus_ATCC_199 KNDDSFYLPPEIFDNPDFKRGLKMFLSPDGKTLRMIISHRGDPTSPEGLS
:********.* *.* :*::.:. *:*.**:: *::: * *:* : .:
MAV_2510|M.avium_104 HIGAIKKAAYEALKGTPLEGSKIYLAGTASIYKDLSDGNNYDLLIAGISS
MUL_0757|M.ulcerans_Agy99 HIDKIKTAAKEAIKGTPLEGSTIYLGGTVAMFKDLSDGNTFDLMIAGISA
MSMEG_0225|M.smegmatis_MC2_155 KIDDIKLAAKEAIKGTPLEGSKIYLGGTAATFKDMQEGANYDLIIAGIAA
TH_3260|M.thermoresistible__bu KIEPIKKAAVEAIKGTPLEGSRVYLGGTAAVFKDMSDGTKYDLIIAAIAA
Mb0458c|M.bovis_AF2122/97 SIDAIRTAAEESLKGTPLEDAKIYLAGTAAVFHDISEGAQWDLLIAAISS
Rv0450c|M.tuberculosis_H37Rv SIDAIRTAAEESLKGTPLEDAKIYLAGTAAVFHDISEGAQWDLLIAAISS
MLBr_02378|M.leprae_Br4923 SINAIRTAAEEALKGTPLEDTKIYLAGTAAVFKDIDEGANWDLVIAGISS
Mflv_2705|M.gilvum_PYR-GCK RVEPIKIAAIEALKGTPLENAQIQLGGTAATFKDMSDGSRYDMMIAILSA
Mvan_3833|M.vanbaalenii_PYR-1 RVEPIKIAAIEALKGTPLENAQIQLGGTAATFKDMSDGSRYDLLIAVISA
MMAR_3174|M.marinum_M RVDPIKLAAIEALKGTPLENAKVSLGGTASVYHDLSEGTRYDLVIAVIAT
MAB_1134c|M.abscessus_ATCC_199 HIEPIKLAAIEAVKGTPLEDAKIELGGTAATFHDMADGARYDLMIAGISA
: *: ** *::******.: : *.**.: ::*: :* :*::** :::
MAV_2510|M.avium_104 LCLIFIIMLIITRGVVASAVIVGTVLLSLGASFGLSVLIWQHLIGIELHW
MUL_0757|M.ulcerans_Agy99 LCLIFIIMLIITRSVVAAAVIVGTVVLSLGASFGLSVLIWQHVLGIELHW
MSMEG_0225|M.smegmatis_MC2_155 LCLIFIIMLIITRAVVASAVIVGTVVISLGSAFGLSVLIWQHLVGLELHW
TH_3260|M.thermoresistible__bu VCLIFIIMLILTRAVVAAAVIVGTVTLSLAASFGVSVLIWQYIVGLEMHW
Mb0458c|M.bovis_AF2122/97 LCLIFIIMLIITRAFIAAAVIVGTVALSLGASFGLSVLLWQHILAIHLHW
Rv0450c|M.tuberculosis_H37Rv LCLIFIIMLIITRAFIAAAVIVGTVALSLGASFGLSVLLWQHILAIHLHW
MLBr_02378|M.leprae_Br4923 LCLIFIIMLIITRAFVAAAVIVGTVALSLGASFGLSVLLWQHILGIELHY
Mflv_2705|M.gilvum_PYR-GCK LCLVLVIMLVLTRSLVAAVVIVGTVALSLGASFGVSVLIWQHLLGVELHW
Mvan_3833|M.vanbaalenii_PYR-1 LCLVLMIMLVLTRSLVAALVIVGTVTLSLGASFGISILIWQHIVGIELHW
MMAR_3174|M.marinum_M VCLIFAIMLLITRSLVAAMVIVGTVLLSLGASVGLSVLLWQYIVGLPLQW
MAB_1134c|M.abscessus_ATCC_199 LCLIFLIMLLITRSFVASLVIVGTVLLSLGASFGLSVIIWQYILGKELHW
:**:: ***::**..:*: ****** :**.::.*:*:::**:::. :::
MAV_2510|M.avium_104 MVLAMSVIILLAVGADYNLLLVARFKEEIHAGLNTGIIRSMGGTGSVVTS
MUL_0757|M.ulcerans_Agy99 LVLAMAVIILLAVGADYNLLLVARLKEEIHAGINTGIIRAMGGSGSVVTA
MSMEG_0225|M.smegmatis_MC2_155 MVLAMAVIVLLAVGADYNLLLVSRIKEEIHAGLDTGMIRAMGGSGSVVTA
TH_3260|M.thermoresistible__bu MVFPMALIILLAVGADYNLLVVARLREEIPAGLNTGMIRAMGGSGSVVTA
Mb0458c|M.bovis_AF2122/97 LVLAMSVIVLLAVGSDYNLLLVSRFKQEIGAGLKTGIIRSMGGTGKVVTN
Rv0450c|M.tuberculosis_H37Rv LVLAMSVIVLLAVGSDYNLLLVSRFKQEIGAGLKTGIIRSMGGTGKVVTN
MLBr_02378|M.leprae_Br4923 LVLAMSVIVLLAVGSDYNLLLVSRFKQEIQAGLKTGIIRSMGGTGKVVTN
Mflv_2705|M.gilvum_PYR-GCK MVLVMSIIALIAVGSDYNLLLVSRFKEEIGAGIKTGIIRAIGGTGSVVSV
Mvan_3833|M.vanbaalenii_PYR-1 MVLALSIIALIAVGSDYNLLLVSRFKEEIPAGIKTGIIRAIGGTGSVVTV
MMAR_3174|M.marinum_M MVMSMAVIILLAVGADYNLMMVARFKEEMPAGLKTGIIRAMGGAGSVVTA
MAB_1134c|M.abscessus_ATCC_199 MVMQMAIIVLLAVGSDYNLLLVSRLKEELPGGLKTGMIRAMGGTGSVVTS
:*: :::* *:***:****::*:*:::*: .*:.**:**::**:*.**:
MAV_2510|M.avium_104 AGLVFAFTMMTMAVSELTVIGQVGTTIGLGLLFDTLIVRSLMTPSIAALL
MUL_0757|M.ulcerans_Agy99 AGLVFAFTMMSFAVSELTVMAQVGTTIGMGLLFDTLIVRSFMTPSIAALL
MSMEG_0225|M.smegmatis_MC2_155 AGLVFAFTMMSMAVSELAIIGQVGTTIGLGLLFDTLVIRSFMTPSIAALL
TH_3260|M.thermoresistible__bu AGLVFGLTMMVMVVSDLTVMGQVGTTIGLGLLFDTFVVRSFMMPSIATLL
Mb0458c|M.bovis_AF2122/97 AGLVFAVTMASMAVSDLRVIGQVGTTIGLGLLFDTLIVRSFMTPSIAALL
Rv0450c|M.tuberculosis_H37Rv AGLVFAVTMASMAVSDLRVIGQVGTTIGLGLLFDTLIVRSFMTPSIAALL
MLBr_02378|M.leprae_Br4923 AGLVFAFTMASMVVSDLRVIGQVGTTIGLGLLFDTLIVRSFMMPSIAALL
Mflv_2705|M.gilvum_PYR-GCK AGVVFALTMASMVVSDLKVIAQVGTTIGLGLLFDTFIVRAFMMPSIATLL
Mvan_3833|M.vanbaalenii_PYR-1 AGVVFALTMASMVVSDLRVMAQVGTTIGLGLLFDTFIVRAFMMPAIATLL
MMAR_3174|M.marinum_M AGLVFAFTMTSMVVSDLRTIGQIGTFIGLGLLFDTLIVRSFMVPSIAALL
MAB_1134c|M.abscessus_ATCC_199 AGLVFAFTMMAMAISDLTIIGQVGTTIGLGLLFDTLVVRSFMTPAIATIL
**:**..** :.:*:* :.*:** **:******:::*::* *:**::*
MAV_2510|M.avium_104 GKWFWWPQRVRQRPVPSP----------WPKPAAQEREVLADA-------
MUL_0757|M.ulcerans_Agy99 GKWFWWPQVVRQRPAPQP----------WPTPAPTPPPATTSV-------
MSMEG_0225|M.smegmatis_MC2_155 GKWFWWPQMVRRRPKPSP----------WPKPIQREPADAVN--------
TH_3260|M.thermoresistible__bu GRWFWWPQFVRKRPVPQP----------WPSVPPRGPATTDRVSV-----
Mb0458c|M.bovis_AF2122/97 GRWFWWPLRVRSRPARTP----------TVPSETQPAGRPLAMSSDRLG-
Rv0450c|M.tuberculosis_H37Rv GRWFWWPLRVRSRPARTP----------TVPSETQPAGRPLAMSSDRLG-
MLBr_02378|M.leprae_Br4923 GRWFWWPQQGRTRPLLTV----------AAPVGLPPD-RSLVYSD-----
Mflv_2705|M.gilvum_PYR-GCK GRWFWWPLVVRSRPLRPR-----------PQQQALGVGGQQG--------
Mvan_3833|M.vanbaalenii_PYR-1 GRWFWWPLVVRSRPLRLP-----------PRT------------------
MMAR_3174|M.marinum_M GRWFWWPINVRTRPARAR-----------PVRPQA---------------
MAB_1134c|M.abscessus_ATCC_199 GRWFWWPLNVRTRPLPPPRTPQPDTTPPPPAPAPVGAGPDPATTEFPRAS
*:***** * **
MAV_2510|M.avium_104 -
MUL_0757|M.ulcerans_Agy99 -
MSMEG_0225|M.smegmatis_MC2_155 -
TH_3260|M.thermoresistible__bu -
Mb0458c|M.bovis_AF2122/97 -
Rv0450c|M.tuberculosis_H37Rv -
MLBr_02378|M.leprae_Br4923 -
Mflv_2705|M.gilvum_PYR-GCK -
Mvan_3833|M.vanbaalenii_PYR-1 -
MMAR_3174|M.marinum_M -
MAB_1134c|M.abscessus_ATCC_199 Y