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M. avium 104 MAV_4755 (-)

annotation: MmpL4 protein
coordinates: 4878158 - 4880971
length: 937

LSLPITLGWVFVAVALGVLSPSLDDVASQHSVPMTPRDAPAFKSMMHIGDKFNEFHTDSTAMVVLEGKDK
LGDSAHEFYDRIVRKLRDDHQHVQNIQDFWSDPLTAAGSQSPDGKSAYVQVFLNGAQGTTPSYESVAAVR
KIVDSTPAPPGVKAYVAGNTVLNADTSIVGHKSMATMALVSIVVIFVMLLVVYRSIVTTVLSLVIIGIEL
FAAQGITATAGNLNIIGLTPYAVSMITMLSIAAGTDYVIFLLGRYHEARSFGQGREEAFYTAYHGVSHVI
LGSGLTIAGACLCLTAARLPYFQTMGLPCAIAMVVIVLAALTLAPAILAVGSRFGLFDPKRAIDVRGWRK
VGTAVVRWPKPIIVVTAAIAVIGFISLLTYVPNYDDQKFTPKDMPANAAMTAAERHFSQARMNPELLMVE
ADHDLRDPADMLVVDRIAKSVFHLRGIERVQTITRPLGAPIEHSSIPFQIAMQNSGTLQTAKFMNDTMAN
MLEQADELDKTIAVMEHMYGVMKELTATTHSMVGRTHEMVDTTNELRDRIADFDDFFRPIRSYFYWEKHC
FDIPVCWSMRSLFDALDGIDELSDQISGLTIDLDHMDRLMPQLLADFPKTIDSMKTMRDFMLSTHSTMAG
IQAHQQEAAEGSTLMGQYFDEAKNDDSFYLPPEVFKNPDFKRGLKMFVSPDGTAVRFIITHQGDPASVEG
IKHVAGVKDAVADAIKGTPLESSKVYLAGTASMYSDMQEGVIIDLLVAGISCLILIFTIMLIITRSVVAA
LVIVGTVAASLGTACGLSVLMWQDLIGLGVQWIVLPLSIVILLAVGSDYNLLLVSRLKEEIPAGLNTGII
RGMGASGRVVTAAGLVFAFTMASMIVSQLRVIGELGTTIALGLLVDTLIVRSFMTPSIAAALGHWFWWPI
NTIRMTRRTHHDEEAHTAPIRQPALR*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. avium 104MAV_4755--100% (937)MmpL4 protein
M. avium 104MAV_4696-0.057.98% (909) MmpL4 protein
M. avium 104MAV_2510-0.057.21% (909) MmpL4 protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0458cmmpL40.060.02% (918) transmembrane transport protein MmpL4
M. gilvum PYR-GCKMflv_4418-0.057.80% (910) transport protein
M. tuberculosis H37RvRv0450cmmpL40.060.13% (918) transmembrane transport protein MmpL4
M. leprae Br4923MLBr_02378-0.058.04% (908) hypothetical protein MLBr_02378
M. abscessus ATCC 19977MAB_4310c-0.072.67% (933) MmpL family protein
M. marinum MMMAR_0775-0.061.17% (909) MmpL family transport protein
M. smegmatis MC2 155MSMEG_0463-0.074.21% (919) MmpL4 protein
M. thermoresistible (build 8)TH_3260-0.052.51% (937) PUTATIVE MmpL4 protein
M. ulcerans Agy99MUL_0757mmpL50.057.10% (909) transmembrane transport protein, MmpL5
M. vanbaalenii PYR-1Mvan_1936-0.057.25% (910) transport protein

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_4418|M.gilvum_PYR-GCK          ---------------------------------MADAGRSGIGRIIRVLA
Mvan_1936|M.vanbaalenii_PYR-1       ---------------------------------MADAGRSGIGRIIHLLA
TH_3260|M.thermoresistible__bu      ------------MTANPGHVRTDEAPTDRLDIKVSTHGPSFISTWIRRLS
MUL_0757|M.ulcerans_Agy99           ------------MTAT-----TTDTPTDVVPPAEHPPRP-FIPRMIRTFA
MMAR_0775|M.marinum_M               MSDDQAVSERAASNGASNGAGAENGNGNENGNGNGNGSRPSMARLIHRMA
Mb0458c|M.bovis_AF2122/97           ----------------------MSTKFANDSNTNARPEKPFIARMIHAFA
Rv0450c|M.tuberculosis_H37Rv        ----------------------MSTKFANDSNTNARPEKPFIARMIHAFA
MLBr_02378|M.leprae_Br4923          ----------------------MTVKCANDLDTHTKP--PFVARMIHRFA
MAB_4310c|M.abscessus_ATCC_199      -----------------------------MSNLHAKPHRPFLGHLIRVLS
MSMEG_0463|M.smegmatis_MC2_155      -----------------------------MTNTHSKSQRPFVGHVIRIFS
MAV_4755|M.avium_104                -----------------------------------------------MLS
                                                                                    ::

Mflv_4418|M.gilvum_PYR-GCK          VPIVLGWVLLTVLTNVAVPSLEKVGEEHTVGMSAGDAPSMMSMKRVGANF
Mvan_1936|M.vanbaalenii_PYR-1       VPIVLGWIALTVLTNVAVPSLEKVGEEHTVGMSANDAPSMMSMERVGANF
TH_3260|M.thermoresistible__bu      LPIIVGWIALIALLNITVPQLEVVGEMRAVSMSPDEAPSMVAMKRVGELF
MUL_0757|M.ulcerans_Agy99           VPLILGWVLLIAVLNSVVPQLEVVGQMQAVSMSPDAAPSMISMKHIGKVF
MMAR_0775|M.marinum_M               VPIVVFWVGLVAVLVMFVPSLEEVGKQHTVSLSPSDAESMIAMKRVGKVF
Mb0458c|M.bovis_AF2122/97           VPIILGWLAVCVVVTVFVPSLEAVGQERSVSLSPKDAPSFEAMGRIGMVF
Rv0450c|M.tuberculosis_H37Rv        VPIILGWLAVCVVVTVFVPSLEAVGQERSVSLSPKDAPSFEAMGRIGMVF
MLBr_02378|M.leprae_Br4923          VPIILVWLAIAVTVSVFIPSLEDVGQERSVSLSPKDAPSYIAMQKMGQVF
MAB_4310c|M.abscessus_ATCC_199      LPIILFWVALAVILGTVTPSLTDVAASRSVPLSPQNSESYQGMLNIGKVF
MSMEG_0463|M.smegmatis_MC2_155      LPIVLLWVLLVVALGAIFPSLDDVAATRSVPLSPTDSQAYQSMLNIGKVF
MAV_4755|M.avium_104                LPITLGWVFVAVALGVLSPSLDDVASQHSVPMTPRDAPAFKSMMHIGDKF
                                    :*: : *: : .      *.*  *.  ::* ::.  : :  .* .:*  *

Mflv_4418|M.gilvum_PYR-GCK          EEFDSDSSAMVVLEGEQPLGDAAHRYYDQLIDELEADTANVQHIADFWGD
Mvan_1936|M.vanbaalenii_PYR-1       DEFDSDSSAMVVLEGEQPLGDAAHRYYDELIGKLEADTANVQHVADFWGD
TH_3260|M.thermoresistible__bu      DEGSSDSQVMIVLEGEEPLGADARAFYDELVKRLEADDAHVENVQDLWSD
MUL_0757|M.ulcerans_Agy99           REGDSDSAAMIVLEGQEPLGAAAHKFYDKMITKLRADTKHVQSVQDFWGD
MMAR_0775|M.marinum_M               NEFDTDSAVMIVLEGDHPLGDEAHHYYDELVRKLKADKDHVQHVQDFWGD
Mb0458c|M.bovis_AF2122/97           KEGDSDSFAMVIIEGNQPLGDAAHKYYDGLVAQLRADKKHVQSVQDLWGD
Rv0450c|M.tuberculosis_H37Rv        KEGDSDSFAMVIIEGNQPLGDAAHKYYDGLVAQLRADKKHVQSVQDLWGD
MLBr_02378|M.leprae_Br4923          NEGNSDSVIMIVLEGDKPLGDDAHRFYDGLIRKLRADK-HVQSVQDFWGD
MAB_4310c|M.abscessus_ATCC_199      QQYDSDSSAMVVLEGDDKLGDSAHQYYDDIVAKLKADHEHVQNVQDFWSD
MSMEG_0463|M.smegmatis_MC2_155      RQYDSDSTAMVVLEGEDKLGDAAHKYYDEIVAKLRADHEHVQNVQDFWSD
MAV_4755|M.avium_104                NEFHTDSTAMVVLEGKDKLGDSAHEFYDRIVRKLRDDHQHVQNIQDFWSD
                                     :  :**  *:::**.. **  *: :** :: .*. *  :*: : *:*.*

Mflv_4418|M.gilvum_PYR-GCK          PLTASGAQSTDGKAAYVQVYLQGNQGEPRANEAVAAVREIVDRTP---AP
Mvan_1936|M.vanbaalenii_PYR-1       PLTASGAQSTDGKAAYVQVYLQGNQGEPRANEAVAAVREIVDQTP---AP
TH_3260|M.thermoresistible__bu      PLTATGVQSPDGKSAYVQVKLAGNQGEALANESVETVREMIATVSEEMAP
MUL_0757|M.ulcerans_Agy99           PLTATGAQSGDGKAAYVQVKLAGNQGESLANESVEAVKTIVDSL---QAP
MMAR_0775|M.marinum_M               PLTAAGSQSPDGKAAYVQAYLVGNQGEAKANESVDAVRELVNDTP---AP
Mb0458c|M.bovis_AF2122/97           PLTAAGVQSNDGKAAYVQLSLAGNQGTPLANESVEAVRSIVESTP---AP
Rv0450c|M.tuberculosis_H37Rv        PLTAAGVQSNDGKAAYVQLSLAGNQGTPLANESVEAVRSIVESTP---AP
MLBr_02378|M.leprae_Br4923          PLTAPGAQSNDGKAAYVQLSLAGNQGELLAQESIDAVRKIVVQTP---AP
MAB_4310c|M.abscessus_ATCC_199      PLTAAGSQSVDGKAAYVQIFLNGSQGTSASHESVAAVRHIVDSVP---AP
MSMEG_0463|M.smegmatis_MC2_155      PLTAAGSQSVDGRSAYVQIFLNGPQGTTASYESVAAVRDIVESVP---PP
MAV_4755|M.avium_104                PLTAAGSQSPDGKSAYVQVFLNGAQGTTPSYESVAAVRKIVDSTP---AP
                                    ****.* ** **::****  * * **   : *:: :*: ::       .*

Mflv_4418|M.gilvum_PYR-GCK          PGIKAYVTGGAPLVADQHSAGDTSVLRVTLITIGVIAVMLLIVFRSVATM
Mvan_1936|M.vanbaalenii_PYR-1       PGLKAYVTGGAPLVADQHNAGDKSVFRVTLITIGVIAVMLLLVFRSVATM
TH_3260|M.thermoresistible__bu      EGVQAFVTGGAAMSADQQEAGDSSLRVIEALTFLVITTMLLFVYRSVITV
MUL_0757|M.ulcerans_Agy99           PGVKVYVTGSAALVADQQLAGDRSLQLIEMVTFTVIIVMLLLVYRSIITA
MMAR_0775|M.marinum_M               PGVKAYVTGPAALIADQSTAGDASIQRVTFITIGVIFVMLLSVYRSLITV
Mb0458c|M.bovis_AF2122/97           PGIKAYVTGPSALAADMHHSGDRSMARITMVTVAVIFIMLLLVYRSIITV
Rv0450c|M.tuberculosis_H37Rv        PGIKAYVTGPSALAADMHHSGDRSMARITMVTVAVIFIMLLLVYRSIITV
MLBr_02378|M.leprae_Br4923          PGITAWVTGASALIADMHHSGDKSMIRITATSVIVILVTLLLVYRSFITV
MAB_4310c|M.abscessus_ATCC_199      PGIKAHVAGTTVLNADTQVAGHQSMATMELVSVGVIIVMILFIYRSIVTM
MSMEG_0463|M.smegmatis_MC2_155      PGIKAHVAGTTVLNADTSVAGHQSMARMELISVAVIILMLLAIYRSIVTM
MAV_4755|M.avium_104                PGVKAYVAGNTVLNADTSIVGHKSMATMALVSIVVIFVMLLVVYRSIVTT
                                     *: . *:* : : **    *. *:  :   :. **   :* ::**. * 

Mflv_4418|M.gilvum_PYR-GCK          VLILFMVFAELGAARGIVAFLADAEIIGLSTFATSLLTLMVIAAGTDYAI
Mvan_1936|M.vanbaalenii_PYR-1       VLILFMVFAELGAARGIVAFLANAEIIGLSTFATSLLTLMVIAAGTDYAI
TH_3260|M.thermoresistible__bu      LIALFMVLIGLLTTRGVVAFLGYHNIIGLSTFATSLLVTLAIAIAVDYAI
MUL_0757|M.ulcerans_Agy99           AIMLTMVVLGLLATRGGVAFLGYHRIIGLSTFATNLLVVLAIAAATDYAI
MMAR_0775|M.marinum_M               ISVLVMVGIELMAARGVVAFLADNNVIGLSTFAVNLLVLMAIAAGTDYAI
Mb0458c|M.bovis_AF2122/97           VLLLITVGVELTAARGVVAVLGHSGAIGLTTFAVSLLTSLAIAAGTDYGI
Rv0450c|M.tuberculosis_H37Rv        VLLLITVGVELTAARGVVAVLGHSGAIGLTTFAVSLLTSLAIAAGTDYGI
MLBr_02378|M.leprae_Br4923          ILLLFTVGIESAVARGVVALLGHTGLIGLSTFAVNLLTSLAIAAGTDYGI
MAB_4310c|M.abscessus_ATCC_199      LISMVIIGLELFAAQGVTATAGYLNVIGLTPYAVSMVTMLALAAGTDYVI
MSMEG_0463|M.smegmatis_MC2_155      LISMVIIGLELFAAQSVTATAGHFNLIGLTPYAVSMTTMLALAAGTDYVI
MAV_4755|M.avium_104                VLSLVIIGIELFAAQGITATAGNLNIIGLTPYAVSMITMLSIAAGTDYVI
                                       :  :     .::. .*  .    ***:.:*..: . : :* ..** *

Mflv_4418|M.gilvum_PYR-GCK          FAIGRYQEARGAGEDRETAYYTMFRGTAHVVLGSGLTIAGAMLCLSFTRL
Mvan_1936|M.vanbaalenii_PYR-1       FAIGRYQEARGAGEDRETAYYTMFRGTAHVVLGSGLTIAGAMLCLSFTRL
TH_3260|M.thermoresistible__bu      FLIGRYQEARSVGADRATAYHTMFGGTAHVILASGLTIAGATFCLSFTRL
MUL_0757|M.ulcerans_Agy99           FLIGRYQEARGLGQDRESAYYTMFGGTAHVVLGSGLTIAGATFCLSFTRL
MMAR_0775|M.marinum_M               FVLGRYQEARGEGESREKAFYTMFHGTAHVVLGSGLTIAGAMYCLSFTRL
Mb0458c|M.bovis_AF2122/97           FIIGRYQEARQAGEDKEAAYYTMYRGTAHVILGSGLTITGATFCLSFARM
Rv0450c|M.tuberculosis_H37Rv        FIIGRYQEARQAGEDKEAAYYTMYRGTAHVILGSGLTIAGATFCLSFARM
MLBr_02378|M.leprae_Br4923          FITGRYQEARQANENKEAAFYTMYRGTFHVILGSGLTISGATFCLSFARM
MAB_4310c|M.abscessus_ATCC_199      FLFGRYHEERSKGLSREDAYYVAYHGVSHVILGSGLTIVGACLCLTMTTL
MSMEG_0463|M.smegmatis_MC2_155      FLLGRYHEERSRGLDREEAYYVAYRGVSHVILGSGLTIAGACLCLTMTTL
MAV_4755|M.avium_104                FLLGRYHEARSFGQGREEAFYTAYHGVSHVILGSGLTIAGACLCLTAARL
                                    *  ***:* *  . .:  *::. : *. **:*.***** **  **: : :

Mflv_4418|M.gilvum_PYR-GCK          PYFQTMGVPCAVGTFVAVIAALTLGPAVIVIGSRFG-LFDPKRAISSRGW
Mvan_1936|M.vanbaalenii_PYR-1       PYFQTMGVPCAVGTFVAVMAALTLGPAVVAIGSRFG-LFDPKRAISSRGW
TH_3260|M.thermoresistible__bu      PYFQSLGPPLAIGMIVLIVTSLTMGPAIITVATRFG-LLEPKRAARVRFW
MUL_0757|M.ulcerans_Agy99           PYFQTLGVPLAIGMVIVVATALTLGPALIAVMSRFGKLLEPKRMARVRGW
MMAR_0775|M.marinum_M               PYFQTLGAPCAVGMLVAVLAALTLGPAVLVVGSFFK-LFDPKRKMRTRGW
Mb0458c|M.bovis_AF2122/97           PYFQTLGIPCAVGMLVAVAVALTLGPAVLHVGSRFG-LFDPKRLLKVRGW
Rv0450c|M.tuberculosis_H37Rv        PYFQTLGIPCAVGMLVAVAVALTLGPAVLHVGSRFG-LFDPKRLLKVRGW
MLBr_02378|M.leprae_Br4923          PYFQTLGVPCAVGMLIAVAVALTLGPAVLTVGSRFG-LFEPKRLIKVRGW
MAB_4310c|M.abscessus_ATCC_199      PYFQSMALPCAISVLVIVAAALTLAPAVLTVASKFG-LLEPRGKLSTTGW
MSMEG_0463|M.smegmatis_MC2_155      PYFQSMALPCAISILVIVIAALTLAPAVLTVASRFG-LLDPKRELSTKSW
MAV_4755|M.avium_104                PYFQTMGLPCAIAMVVIVLAALTLAPAILAVGSRFG-LFDPKRAIDVRGW
                                    ****::. * *:. .: : .:**:.**:: : : *  *::*:       *

Mflv_4418|M.gilvum_PYR-GCK          RRIGVSVVRWPGPVLAATLALALVGLVTLPGYKTNYDARDYLPEDIPANV
Mvan_1936|M.vanbaalenii_PYR-1       RRIGVSVVRWPGPVLAATLALALVGLVALPGYKTNYDSRDYLPEDVPANV
TH_3260|M.thermoresistible__bu      RKVGASVVRWPGPIMVTTVAVTLVGLLALPGYRTNYNDRNYLPASFPSNA
MUL_0757|M.ulcerans_Agy99           RKIGAAIVRWPGPILIGAVALALVGLLTLPGYKTNYNDRNYLPADLPANE
MMAR_0775|M.marinum_M               RRVGTAIVRWPGPILAVSIAIALIGLLALPGYRTNYDSKKYLPASTPTNV
Mb0458c|M.bovis_AF2122/97           RRVGTVVVRWPLPVLVATCAIALVGLLALPGYKTSYNDRDYLPDFIPANQ
Rv0450c|M.tuberculosis_H37Rv        RRVGTVVVRWPLPVLVATCAIALVGLLALPGYKTSYNDRDYLPDFIPANQ
MLBr_02378|M.leprae_Br4923          RRIGTVVVRWPLPILITTCAIAMVGLLALPGYRTNYKDRAYLPASIPANQ
MAB_4310c|M.abscessus_ATCC_199      RKVGTSVVRWPIPIIVLTSLIAIIGFVSLMTYVPQYNDQKFTPADMPANL
MSMEG_0463|M.smegmatis_MC2_155      RKVGTAVVRWPIPIILVTGLVAAIGFASLLTYVPQYNDQKFTPADMPANV
MAV_4755|M.avium_104                RKVGTAVVRWPKPIIVVTAAIAVIGFISLLTYVPNYDDQKFTPKDMPANA
                                    *::*. :**** *::  :  :: :*: :*  * ..*. : : *   *:* 

Mflv_4418|M.gilvum_PYR-GCK          GYAVADQHFGSARMNPELLMVESDHDLRNPADFLVIDKIAKSVFRVPGVA
Mvan_1936|M.vanbaalenii_PYR-1       GYAVADRHFGSARMNPELLMVESDHDLRNPADFLVIDKIAKAIFRVPGVA
TH_3260|M.thermoresistible__bu      GYEAAERHFDPARLNPELLLIESDHDLRNPADFLVIEKIAKAVFQVEGIS
MUL_0757|M.ulcerans_Agy99           GYSAAERHFSQARMNPEVLMVESDHDMRNSSDFLVINKIAKAIFGVEGIS
MMAR_0775|M.marinum_M               GYTAADRHFSQARMNPELLMVETDHDMRNPADMLVIDRIAKGVFHLPGVA
Mb0458c|M.bovis_AF2122/97           GYAAADRHFSQARMKPEILMIESDHDMRNPADFLVLDKLAKGIFRVPGIS
Rv0450c|M.tuberculosis_H37Rv        GYAAADRHFSQARMKPEILMIESDHDMRNPADFLVLDKLAKGIFRVPGIS
MLBr_02378|M.leprae_Br4923          GFAAADRHFPQARMKPEILMIESDHDMRNPADFLILDKLARGIFRVPGIS
MAB_4310c|M.abscessus_ATCC_199      AMEVADRHFSQARMNPELLMLEADHDLRTPADMLVIDRVAKGIVHMRGIE
MSMEG_0463|M.smegmatis_MC2_155      AMAVADRHFSEARMNPELLMLEADHDIRNPADMLVIDRVAKYVVHMRGIE
MAV_4755|M.avium_104                AMTAAERHFSQARMNPELLMVEADHDLRDPADMLVVDRIAKSVFHLRGIE
                                    .  .*::**  **::**:*::*:***:* .:*:*:::::*: :. : *: 

Mflv_4418|M.gilvum_PYR-GCK          RVQTITRPDGKPIKHTTIPFQMSMQGTTQRLNEKYLQDRMADMLVQADAM
Mvan_1936|M.vanbaalenii_PYR-1       RVQTITRPDGKPIKHTTIPFQMSMRSTTSRLNEKYMQDRMADMLVQADAM
TH_3260|M.thermoresistible__bu      RVQGITRPEGTPIEHSSIPFMISQQGTLQILNQQYMQDRMADMLVQADEM
MUL_0757|M.ulcerans_Agy99           RVQAITRPDGKPIEHTSIPFLISMQGTSQKLTEKYNQDLTTSMLQQVNDI
MMAR_0775|M.marinum_M               RVQAVTRPLGKPIEHSSIPFQISMQNTVQVENMQYMKQRMADMLIQAAAM
Mb0458c|M.bovis_AF2122/97           RVQAITRPEGTTMDHTSIPFQISMQNAGQLQTIKYQRDRANDMLKQADEM
Rv0450c|M.tuberculosis_H37Rv        RVQAITRPEGTTMDHTSIPFQISMQNAGQLQTIKYQRDRANDMLKQADEM
MLBr_02378|M.leprae_Br4923          RVQAITRPDGTAMDHTSIPFQISMQNAGQVQTMKYQKDRMNDLLRQAENM
MAB_4310c|M.abscessus_ATCC_199      RVQTITRPLGAPIEHSSIPFLMGAQNAGTLQTAKFNNENSAQMLEQADEL
MSMEG_0463|M.smegmatis_MC2_155      RVQTITRPLGSPIEHSSIPFLLGAQNAGTMQAAKFNNDNTAQMLEQADEL
MAV_4755|M.avium_104                RVQTITRPLGAPIEHSSIPFQIAMQNSGTLQTAKFMNDTMANMLEQADEL
                                    *** :*** * .:.*::*** :. :.:      :: .:   .:* *.  :

Mflv_4418|M.gilvum_PYR-GCK          QTNVDTMTRMQSLMGQMSATTHEMVLKTKKTEIDIIEVRDNLADFDDFFR
Mvan_1936|M.vanbaalenii_PYR-1       QTNVDTMTKMQSLMTQMSAATHDMVTKTKKTAVDIVEVRDYLANLDDFVR
TH_3260|M.thermoresistible__bu      QLMIDTMDKMIALMEEMVETTDNMVRDMDEMAAHVAEMRDSISEFDDFFR
MUL_0757|M.ulcerans_Agy99           QTNIDQMERMHDLTQQMADVTHQMVIQMKGMVVDVEELRNHIADFDDFFR
MMAR_0775|M.marinum_M               QDSIDTLDRMYDIMGKMVETTHDMDGLTHDMVEITDELRDHIADFDDFWR
Mb0458c|M.bovis_AF2122/97           ATTIAVLTRMHSLMAEMASTTHRMVGDTEEMKEITEELRDHVADFDDFWR
Rv0450c|M.tuberculosis_H37Rv        ATTIAVLTRMHSLMAEMASTTHRMVGDTEEMKEITEELRDHVADFDDFWR
MLBr_02378|M.leprae_Br4923          AETIASMRRMHQLMALLTENTHHILNDTVEMQKTTSKLRDEIANFDDFWR
MAB_4310c|M.abscessus_ATCC_199      SRTVASMERMYSLMQELTGTMHSMVGRTHEMEATIQEMRDNLANFDDFFR
MSMEG_0463|M.smegmatis_MC2_155      SRTIASMERMYGLTQELTDTTHSMVGRTHDMVEATKEMRDSLADFDDFFR
MAV_4755|M.avium_104                DKTIAVMEHMYGVMKELTATTHSMVGRTHEMVDTTNELRDRIADFDDFFR
                                       :  : :*  :   :    . :            ::*: ::::*** *

Mflv_4418|M.gilvum_PYR-GCK          PVRNYFYWEPHCYDIPVCWTMRSVFDTLDGINPLTDDISELIPDLERLDE
Mvan_1936|M.vanbaalenii_PYR-1       PVRNYFYWEPHCYNIPVCATMRSVFDTLDGINPLTDDIQELIPDLERLDA
TH_3260|M.thermoresistible__bu      PIRNYFYWEPHCYNIPVCWAMRSVFDTLDGINTMTDDIQNMLPHMHRLND
MUL_0757|M.ulcerans_Agy99           PIRSYFYWEKHCFDIPVCWSLRSVFDTLDGVDLMTEDINNLLPLMERLDT
MMAR_0775|M.marinum_M               PIRSYFYWEKHCYDVPICWSLRSIFDALDGVDKITEKLAALSRDMDRLDI
Mb0458c|M.bovis_AF2122/97           PIRSYFYWEKHCYGIPICWSFRSIFDALDGIDKLSEQIGVLLGDLREMDR
Rv0450c|M.tuberculosis_H37Rv        PIRSYFYWEKHCYGIPICWSFRSIFDALDGIDKLSEQIGVLLGDLREMDR
MLBr_02378|M.leprae_Br4923          PIRSYFYWERHCFNIPICWSFRSIFDALDGVDQIDERLNSIVGDIKNMDL
MAB_4310c|M.abscessus_ATCC_199      PLRNYFYWEKHCFDIPICQSLRSIFDVLDSVDVLADQMHGLIADMDHMDQ
MSMEG_0463|M.smegmatis_MC2_155      PMRNYLYWEPHCYDIPVCQSLRSVFDTLDGIGQLTDEMQGLTIDMDRMDE
MAV_4755|M.avium_104                PIRSYFYWEKHCFDIPVCWSMRSLFDALDGIDELSDQISGLTIDLDHMDR
                                    *:*.*:*** **:.:*:* ::**:**.**.:. : : :  :   : .:: 

Mflv_4418|M.gilvum_PYR-GCK          LMPQLIALLPSQIETMRSMQAMMLRQYQTQKGQLDQNAAMSEDADAMGEA
Mvan_1936|M.vanbaalenii_PYR-1       LMPQLIALLPSQIESMRNMQSMMLTMYQSQKGLQDQMASQSEDADAMGEA
TH_3260|M.thermoresistible__bu      LMPQMLTLLPTTVATMKTMRSMLLTMQATNAGLQDQMAEMQENANAMGEA
MUL_0757|M.ulcerans_Agy99           LMPQMTAMMPEMIQTMKSMKAQMLSMHSTQQGLQDQMAAMQEDSSAMGEA
MMAR_0775|M.marinum_M               LMPQMRAQIPFQIASMKTMKTMMLTMHSSMSSLYDQMDEMSKNSTAMGKA
Mb0458c|M.bovis_AF2122/97           LMPQMVAQIPPQIEAMENMRTMILTMHSTMTGIFDQMLEMSDNATAMGKA
Rv0450c|M.tuberculosis_H37Rv        LMPQMVAQIPPQIEAMENMRTMILTMHSTMTGIFDQMLEMSDNATAMGKA
MLBr_02378|M.leprae_Br4923          LMPQMLEQFPPMIESMESMRTIMLTMHSTMSGIFDQMNELSDNANTMGKA
MAB_4310c|M.abscessus_ATCC_199      LMPQMLPVLRTTIDSMGRMRDFMIATHSTMAGTQAQQQELAKGATEIGLY
MSMEG_0463|M.smegmatis_MC2_155      LMPQMLPILRSTIDSMKTMRDFMIATHSVMAGTQAQQQELAKNATEIGLY
MAV_4755|M.avium_104                LMPQLLADFPKTIDSMKTMRDFMLSTHSTMAGIQAHQQEAAEGSTLMGQY
                                    ****:   :   : :*  *:  ::       .   :     ..:  :*  

Mflv_4418|M.gilvum_PYR-GCK          FDDSMNDDSFYLPPEAFDNDDFKRGMENFISPDGRSVRFIISHEGDPATV
Mvan_1936|M.vanbaalenii_PYR-1       FDDSMNDDSFYLPPEAFDNDDFKRGIENFISPDGKSVRFIIAHEGDPATV
TH_3260|M.thermoresistible__bu      FDQARNDDSFYLPPEAFDNPDFQRGLEQFLSPDGHAVRFIISHQGDPMTP
MUL_0757|M.ulcerans_Agy99           FDSSRNDDSFYLPPEVFNNPDFKRGLEQFLSPDGHAVRFIISHEGDPMSQ
MMAR_0775|M.marinum_M               FDAARNDDSFYIPPEVFDNADFKRGLKMFLSPDGHAVRFIISHEGDPAST
Mb0458c|M.bovis_AF2122/97           FDAAKNDDSFYLPPEVFKNKDFQRAMKSFLSSDGHAARFIILHRGDPQSP
Rv0450c|M.tuberculosis_H37Rv        FDAAKNDDSFYLPPEVFKNKDFQRAMKSFLSSDGHAARFIILHRGDPQSP
MLBr_02378|M.leprae_Br4923          FDTAKNDDSFYLPPEVFKNTDFKRAMKSFLSSDGHAARFIILHRGDPASV
MAB_4310c|M.abscessus_ATCC_199      FDQAKNDDFFYLPPDVFTNPDFKRGLKMFVSPDGKAVRFIITHQGDPASV
MSMEG_0463|M.smegmatis_MC2_155      FDQAKNDDFFYLPPDVFDNPDFKRGLEMFVSPDGKAVRMIITHQGDPASV
MAV_4755|M.avium_104                FDEAKNDDSFYLPPEVFKNPDFKRGLKMFVSPDGTAVRFIITHQGDPASV
                                    ** : *** **:**:.* * **:*.:: *:*.** :.*:** *.*** : 

Mflv_4418|M.gilvum_PYR-GCK          EGISEVVPIKTAAKEAIKGTPLEGSTVYLAGTAATYKDMSDGAFYDLLIA
Mvan_1936|M.vanbaalenii_PYR-1       EGISRVLPIKTAAKEAIKGTPLEGSTVYLAGTAATYKDMRDGANYDLLIA
TH_3260|M.thermoresistible__bu      EGLAKIEPIKKAAVEAIKGTPLEGSRVYLGGTAAVFKDMSDGTKYDLIIA
MUL_0757|M.ulcerans_Agy99           AGINHIDKIKTAAKEAIKGTPLEGSTIYLGGTVAMFKDLSDGNTFDLMIA
MMAR_0775|M.marinum_M               EGISHVKPIMDEAKQAIKGTPLEGAKIYLAGTASVYKDMRDGSRWDLLIA
Mb0458c|M.bovis_AF2122/97           EGIKSIDAIRTAAEESLKGTPLEDAKIYLAGTAAVFHDISEGAQWDLLIA
Rv0450c|M.tuberculosis_H37Rv        EGIKSIDAIRTAAEESLKGTPLEDAKIYLAGTAAVFHDISEGAQWDLLIA
MLBr_02378|M.leprae_Br4923          AGIASINAIRTAAEEALKGTPLEDTKIYLAGTAAVFKDIDEGANWDLVIA
MAB_4310c|M.abscessus_ATCC_199      EGIDHVRDLKGVVADAVKGTPLSNAKVSIAGTASMYADMQDGVSIDLMIA
MSMEG_0463|M.smegmatis_MC2_155      DGIAHVRDLRDVVADAVKGTPLANAKVSLAGTASLYSDMQDGVVTDLMIA
MAV_4755|M.avium_104                EGIKHVAGVKDAVADAIKGTPLESSKVYLAGTASMYSDMQEGVIIDLLVA
                                     *:  :  :   . :::***** .: : :.**.: : *: :*   **::*

Mflv_4418|M.gilvum_PYR-GCK          GIAAVTLIFVIMLVITRSVVAAAVIVGTVLLSLGASFGLSVLLWQHIIGL
Mvan_1936|M.vanbaalenii_PYR-1       GIAAVTLIFVIMLIITRSVVAAAVIVGTVLLSLGASFGLSVLLWQHIIGL
TH_3260|M.thermoresistible__bu      AIAAVCLIFIIMLILTRAVVAAAVIVGTVTLSLAASFGVSVLIWQYIVGL
MUL_0757|M.ulcerans_Agy99           GISALCLIFIIMLIITRSVVAAAVIVGTVVLSLGASFGLSVLIWQHVLGI
MMAR_0775|M.marinum_M               GVAAVSLILIIMLIITRSLVAAVVIVGTVLLSLGASFGLSVLVWQDIFGV
Mb0458c|M.bovis_AF2122/97           AISSLCLIFIIMLIITRAFIAAAVIVGTVALSLGASFGLSVLLWQHILAI
Rv0450c|M.tuberculosis_H37Rv        AISSLCLIFIIMLIITRAFIAAAVIVGTVALSLGASFGLSVLLWQHILAI
MLBr_02378|M.leprae_Br4923          GISSLCLIFIIMLIITRAFVAAAVIVGTVALSLGASFGLSVLLWQHILGI
MAB_4310c|M.abscessus_ATCC_199      VIASMILIFAIMVLITRSVVAALVIVGTVAASLGTACGLSVLLWQDILGL
MSMEG_0463|M.smegmatis_MC2_155      IIASMILIFGIMLVITRSVVAALVIVGTVAASLGTACGLSVLLWQDILGL
MAV_4755|M.avium_104                GISCLILIFTIMLIITRSVVAALVIVGTVAASLGTACGLSVLMWQDLIGL
                                     ::.: **: **:::**:.:** ******  **.:: *:***:** :..:

Mflv_4418|M.gilvum_PYR-GCK          ALHWMVLPMAVILLLAVGSDYNLLLVSRFKEELSGGLKTGIIRAMAGTGS
Mvan_1936|M.vanbaalenii_PYR-1       ALHWMVLPMAVILLLAVGSDYNLLLVSRFKEELAGGLKTGIIRSMAGTGS
TH_3260|M.thermoresistible__bu      EMHWMVFPMALIILLAVGADYNLLVVARLREEIPAGLNTGMIRAMGGSGS
MUL_0757|M.ulcerans_Agy99           ELHWLVLAMAVIILLAVGADYNLLLVARLKEEIHAGINTGIIRAMGGSGS
MMAR_0775|M.marinum_M               ELHWMVLAMSVILLLAVGSDYNLLLVSRLKEEIGAGLKTGIIRAMAGTGG
Mb0458c|M.bovis_AF2122/97           HLHWLVLAMSVIVLLAVGSDYNLLLVSRFKQEIGAGLKTGIIRSMGGTGK
Rv0450c|M.tuberculosis_H37Rv        HLHWLVLAMSVIVLLAVGSDYNLLLVSRFKQEIGAGLKTGIIRSMGGTGK
MLBr_02378|M.leprae_Br4923          ELHYLVLAMSVIVLLAVGSDYNLLLVSRFKQEIQAGLKTGIIRSMGGTGK
MAB_4310c|M.abscessus_ATCC_199      GVQWIVIPLSMVILLAVGSDYNLLVVSRLKEEIHAGLNTGMIRGMGATGR
MSMEG_0463|M.smegmatis_MC2_155      GVQWVVLPLSIVILLAVGSDYNLLLVSRLKEEIHAGLNTGIIRGMGATGR
MAV_4755|M.avium_104                GVQWIVLPLSIVILLAVGSDYNLLLVSRLKEEIPAGLNTGIIRGMGASGR
                                     ::::*:.:::::*****:*****:*:*:::*: .*::**:**.*..:* 

Mflv_4418|M.gilvum_PYR-GCK          VVTSAGLVFAFTMASFAFSDLKVMAQVGTTIALGLLFDTLIVRSFMTPAV
Mvan_1936|M.vanbaalenii_PYR-1       VVTSAGLVFAFTMASFAFSDLKVMAQVGTTIALGLLFDTLIVRSFMTPAV
TH_3260|M.thermoresistible__bu      VVTAAGLVFGLTMMVMVVSDLTVMGQVGTTIGLGLLFDTFVVRSFMMPSI
MUL_0757|M.ulcerans_Agy99           VVTAAGLVFAFTMMSFAVSELTVMAQVGTTIGMGLLFDTLIVRSFMTPSI
MMAR_0775|M.marinum_M               VVTTAGLVFAATMASFIFSDLRVIGQVGTTIGLGLLFDTLIVRSFMTPSI
Mb0458c|M.bovis_AF2122/97           VVTNAGLVFAVTMASMAVSDLRVIGQVGTTIGLGLLFDTLIVRSFMTPSI
Rv0450c|M.tuberculosis_H37Rv        VVTNAGLVFAVTMASMAVSDLRVIGQVGTTIGLGLLFDTLIVRSFMTPSI
MLBr_02378|M.leprae_Br4923          VVTNAGLVFAFTMASMVVSDLRVIGQVGTTIGLGLLFDTLIVRSFMMPSI
MAB_4310c|M.abscessus_ATCC_199      VVTAAGLVFAFTMMSMIVSDLRVVGQLGMTIGIGLIVDTLIVRAFMTPSI
MSMEG_0463|M.smegmatis_MC2_155      VVTAAGLVFAFTMMAMIVSDLRVVGQLGTTIGLGLIVDTLIVRAFMTPSI
MAV_4755|M.avium_104                VVTAAGLVFAFTMASMIVSQLRVIGELGTTIALGLLVDTLIVRSFMTPSI
                                    *** *****. **  : .*:* *:.::* **.:**:.**::**:** *::

Mflv_4418|M.gilvum_PYR-GCK          AALLGRWFWWPQKFRSAASERRLARIGVQPATAGR---------------
Mvan_1936|M.vanbaalenii_PYR-1       AALLGRWFWWPQKVRSHASQRRLAALNH----------------------
TH_3260|M.thermoresistible__bu      ATLLGRWFWWPQFVRKRPVPQPWPSVPPRGPATTDRVSV-----------
MUL_0757|M.ulcerans_Agy99           AALLGKWFWWPQVVRQRPAPQPWPTPAPTPPPATTSV-------------
MMAR_0775|M.marinum_M               AALMGRWFWWPQQVRTRPASQLLRPYGPRPLVRALLLPRNGDSADGPEDT
Mb0458c|M.bovis_AF2122/97           AALLGRWFWWPLRVRSRPARTPTVPSETQPAGRPLAMSSDRLG-------
Rv0450c|M.tuberculosis_H37Rv        AALLGRWFWWPLRVRSRPARTPTVPSETQPAGRPLAMSSDRLG-------
MLBr_02378|M.leprae_Br4923          AALLGRWFWWPQQGRTRPLLTVAAPVGLPPD-RSLVYSD-----------
MAB_4310c|M.abscessus_ATCC_199      AAALGRWFWWPINVFEIVRRGRETQAPEPVTAPLPVVDAGPQPPTAPSTS
MSMEG_0463|M.smegmatis_MC2_155      AAALGRWFWWPLNTFEITRRGR--QAPHARS-----VDGNTQPFPGVTTA
MAV_4755|M.avium_104                AAALGHWFWWPINTIRMTRRTHHDEEAHTAP--------IRQPALR----
                                    *: :*:*****                                       

Mflv_4418|M.gilvum_PYR-GCK          ------------
Mvan_1936|M.vanbaalenii_PYR-1       ------------
TH_3260|M.thermoresistible__bu      ------------
MUL_0757|M.ulcerans_Agy99           ------------
MMAR_0775|M.marinum_M               NTERLAVSSPHY
Mb0458c|M.bovis_AF2122/97           ------------
Rv0450c|M.tuberculosis_H37Rv        ------------
MLBr_02378|M.leprae_Br4923          ------------
MAB_4310c|M.abscessus_ATCC_199      ------------
MSMEG_0463|M.smegmatis_MC2_155      P-----------
MAV_4755|M.avium_104                ------------