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LSLPITLGWVFVAVALGVLSPSLDDVASQHSVPMTPRDAPAFKSMMHIGDKFNEFHTDSTAMVVLEGKDK LGDSAHEFYDRIVRKLRDDHQHVQNIQDFWSDPLTAAGSQSPDGKSAYVQVFLNGAQGTTPSYESVAAVR KIVDSTPAPPGVKAYVAGNTVLNADTSIVGHKSMATMALVSIVVIFVMLLVVYRSIVTTVLSLVIIGIEL FAAQGITATAGNLNIIGLTPYAVSMITMLSIAAGTDYVIFLLGRYHEARSFGQGREEAFYTAYHGVSHVI LGSGLTIAGACLCLTAARLPYFQTMGLPCAIAMVVIVLAALTLAPAILAVGSRFGLFDPKRAIDVRGWRK VGTAVVRWPKPIIVVTAAIAVIGFISLLTYVPNYDDQKFTPKDMPANAAMTAAERHFSQARMNPELLMVE ADHDLRDPADMLVVDRIAKSVFHLRGIERVQTITRPLGAPIEHSSIPFQIAMQNSGTLQTAKFMNDTMAN MLEQADELDKTIAVMEHMYGVMKELTATTHSMVGRTHEMVDTTNELRDRIADFDDFFRPIRSYFYWEKHC FDIPVCWSMRSLFDALDGIDELSDQISGLTIDLDHMDRLMPQLLADFPKTIDSMKTMRDFMLSTHSTMAG IQAHQQEAAEGSTLMGQYFDEAKNDDSFYLPPEVFKNPDFKRGLKMFVSPDGTAVRFIITHQGDPASVEG IKHVAGVKDAVADAIKGTPLESSKVYLAGTASMYSDMQEGVIIDLLVAGISCLILIFTIMLIITRSVVAA LVIVGTVAASLGTACGLSVLMWQDLIGLGVQWIVLPLSIVILLAVGSDYNLLLVSRLKEEIPAGLNTGII RGMGASGRVVTAAGLVFAFTMASMIVSQLRVIGELGTTIALGLLVDTLIVRSFMTPSIAAALGHWFWWPI NTIRMTRRTHHDEEAHTAPIRQPALR*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. avium 104 | MAV_4755 | - | - | 100% (937) | MmpL4 protein |
M. avium 104 | MAV_4696 | - | 0.0 | 57.98% (909) | MmpL4 protein |
M. avium 104 | MAV_2510 | - | 0.0 | 57.21% (909) | MmpL4 protein |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb0458c | mmpL4 | 0.0 | 60.02% (918) | transmembrane transport protein MmpL4 |
M. gilvum PYR-GCK | Mflv_4418 | - | 0.0 | 57.80% (910) | transport protein |
M. tuberculosis H37Rv | Rv0450c | mmpL4 | 0.0 | 60.13% (918) | transmembrane transport protein MmpL4 |
M. leprae Br4923 | MLBr_02378 | - | 0.0 | 58.04% (908) | hypothetical protein MLBr_02378 |
M. abscessus ATCC 19977 | MAB_4310c | - | 0.0 | 72.67% (933) | MmpL family protein |
M. marinum M | MMAR_0775 | - | 0.0 | 61.17% (909) | MmpL family transport protein |
M. smegmatis MC2 155 | MSMEG_0463 | - | 0.0 | 74.21% (919) | MmpL4 protein |
M. thermoresistible (build 8) | TH_3260 | - | 0.0 | 52.51% (937) | PUTATIVE MmpL4 protein |
M. ulcerans Agy99 | MUL_0757 | mmpL5 | 0.0 | 57.10% (909) | transmembrane transport protein, MmpL5 |
M. vanbaalenii PYR-1 | Mvan_1936 | - | 0.0 | 57.25% (910) | transport protein |
CLUSTAL 2.0.9 multiple sequence alignment Mflv_4418|M.gilvum_PYR-GCK ---------------------------------MADAGRSGIGRIIRVLA Mvan_1936|M.vanbaalenii_PYR-1 ---------------------------------MADAGRSGIGRIIHLLA TH_3260|M.thermoresistible__bu ------------MTANPGHVRTDEAPTDRLDIKVSTHGPSFISTWIRRLS MUL_0757|M.ulcerans_Agy99 ------------MTAT-----TTDTPTDVVPPAEHPPRP-FIPRMIRTFA MMAR_0775|M.marinum_M MSDDQAVSERAASNGASNGAGAENGNGNENGNGNGNGSRPSMARLIHRMA Mb0458c|M.bovis_AF2122/97 ----------------------MSTKFANDSNTNARPEKPFIARMIHAFA Rv0450c|M.tuberculosis_H37Rv ----------------------MSTKFANDSNTNARPEKPFIARMIHAFA MLBr_02378|M.leprae_Br4923 ----------------------MTVKCANDLDTHTKP--PFVARMIHRFA MAB_4310c|M.abscessus_ATCC_199 -----------------------------MSNLHAKPHRPFLGHLIRVLS MSMEG_0463|M.smegmatis_MC2_155 -----------------------------MTNTHSKSQRPFVGHVIRIFS MAV_4755|M.avium_104 -----------------------------------------------MLS :: Mflv_4418|M.gilvum_PYR-GCK VPIVLGWVLLTVLTNVAVPSLEKVGEEHTVGMSAGDAPSMMSMKRVGANF Mvan_1936|M.vanbaalenii_PYR-1 VPIVLGWIALTVLTNVAVPSLEKVGEEHTVGMSANDAPSMMSMERVGANF TH_3260|M.thermoresistible__bu LPIIVGWIALIALLNITVPQLEVVGEMRAVSMSPDEAPSMVAMKRVGELF MUL_0757|M.ulcerans_Agy99 VPLILGWVLLIAVLNSVVPQLEVVGQMQAVSMSPDAAPSMISMKHIGKVF MMAR_0775|M.marinum_M VPIVVFWVGLVAVLVMFVPSLEEVGKQHTVSLSPSDAESMIAMKRVGKVF Mb0458c|M.bovis_AF2122/97 VPIILGWLAVCVVVTVFVPSLEAVGQERSVSLSPKDAPSFEAMGRIGMVF Rv0450c|M.tuberculosis_H37Rv VPIILGWLAVCVVVTVFVPSLEAVGQERSVSLSPKDAPSFEAMGRIGMVF MLBr_02378|M.leprae_Br4923 VPIILVWLAIAVTVSVFIPSLEDVGQERSVSLSPKDAPSYIAMQKMGQVF MAB_4310c|M.abscessus_ATCC_199 LPIILFWVALAVILGTVTPSLTDVAASRSVPLSPQNSESYQGMLNIGKVF MSMEG_0463|M.smegmatis_MC2_155 LPIVLLWVLLVVALGAIFPSLDDVAATRSVPLSPTDSQAYQSMLNIGKVF MAV_4755|M.avium_104 LPITLGWVFVAVALGVLSPSLDDVASQHSVPMTPRDAPAFKSMMHIGDKF :*: : *: : . *.* *. ::* ::. : : .* .:* * Mflv_4418|M.gilvum_PYR-GCK EEFDSDSSAMVVLEGEQPLGDAAHRYYDQLIDELEADTANVQHIADFWGD Mvan_1936|M.vanbaalenii_PYR-1 DEFDSDSSAMVVLEGEQPLGDAAHRYYDELIGKLEADTANVQHVADFWGD TH_3260|M.thermoresistible__bu DEGSSDSQVMIVLEGEEPLGADARAFYDELVKRLEADDAHVENVQDLWSD MUL_0757|M.ulcerans_Agy99 REGDSDSAAMIVLEGQEPLGAAAHKFYDKMITKLRADTKHVQSVQDFWGD MMAR_0775|M.marinum_M NEFDTDSAVMIVLEGDHPLGDEAHHYYDELVRKLKADKDHVQHVQDFWGD Mb0458c|M.bovis_AF2122/97 KEGDSDSFAMVIIEGNQPLGDAAHKYYDGLVAQLRADKKHVQSVQDLWGD Rv0450c|M.tuberculosis_H37Rv KEGDSDSFAMVIIEGNQPLGDAAHKYYDGLVAQLRADKKHVQSVQDLWGD MLBr_02378|M.leprae_Br4923 NEGNSDSVIMIVLEGDKPLGDDAHRFYDGLIRKLRADK-HVQSVQDFWGD MAB_4310c|M.abscessus_ATCC_199 QQYDSDSSAMVVLEGDDKLGDSAHQYYDDIVAKLKADHEHVQNVQDFWSD MSMEG_0463|M.smegmatis_MC2_155 RQYDSDSTAMVVLEGEDKLGDAAHKYYDEIVAKLRADHEHVQNVQDFWSD MAV_4755|M.avium_104 NEFHTDSTAMVVLEGKDKLGDSAHEFYDRIVRKLRDDHQHVQNIQDFWSD : :** *:::**.. ** *: :** :: .*. * :*: : *:*.* Mflv_4418|M.gilvum_PYR-GCK PLTASGAQSTDGKAAYVQVYLQGNQGEPRANEAVAAVREIVDRTP---AP Mvan_1936|M.vanbaalenii_PYR-1 PLTASGAQSTDGKAAYVQVYLQGNQGEPRANEAVAAVREIVDQTP---AP TH_3260|M.thermoresistible__bu PLTATGVQSPDGKSAYVQVKLAGNQGEALANESVETVREMIATVSEEMAP MUL_0757|M.ulcerans_Agy99 PLTATGAQSGDGKAAYVQVKLAGNQGESLANESVEAVKTIVDSL---QAP MMAR_0775|M.marinum_M PLTAAGSQSPDGKAAYVQAYLVGNQGEAKANESVDAVRELVNDTP---AP Mb0458c|M.bovis_AF2122/97 PLTAAGVQSNDGKAAYVQLSLAGNQGTPLANESVEAVRSIVESTP---AP Rv0450c|M.tuberculosis_H37Rv PLTAAGVQSNDGKAAYVQLSLAGNQGTPLANESVEAVRSIVESTP---AP MLBr_02378|M.leprae_Br4923 PLTAPGAQSNDGKAAYVQLSLAGNQGELLAQESIDAVRKIVVQTP---AP MAB_4310c|M.abscessus_ATCC_199 PLTAAGSQSVDGKAAYVQIFLNGSQGTSASHESVAAVRHIVDSVP---AP MSMEG_0463|M.smegmatis_MC2_155 PLTAAGSQSVDGRSAYVQIFLNGPQGTTASYESVAAVRDIVESVP---PP MAV_4755|M.avium_104 PLTAAGSQSPDGKSAYVQVFLNGAQGTTPSYESVAAVRKIVDSTP---AP ****.* ** **::**** * * ** : *:: :*: :: .* Mflv_4418|M.gilvum_PYR-GCK PGIKAYVTGGAPLVADQHSAGDTSVLRVTLITIGVIAVMLLIVFRSVATM Mvan_1936|M.vanbaalenii_PYR-1 PGLKAYVTGGAPLVADQHNAGDKSVFRVTLITIGVIAVMLLLVFRSVATM TH_3260|M.thermoresistible__bu EGVQAFVTGGAAMSADQQEAGDSSLRVIEALTFLVITTMLLFVYRSVITV MUL_0757|M.ulcerans_Agy99 PGVKVYVTGSAALVADQQLAGDRSLQLIEMVTFTVIIVMLLLVYRSIITA MMAR_0775|M.marinum_M PGVKAYVTGPAALIADQSTAGDASIQRVTFITIGVIFVMLLSVYRSLITV Mb0458c|M.bovis_AF2122/97 PGIKAYVTGPSALAADMHHSGDRSMARITMVTVAVIFIMLLLVYRSIITV Rv0450c|M.tuberculosis_H37Rv PGIKAYVTGPSALAADMHHSGDRSMARITMVTVAVIFIMLLLVYRSIITV MLBr_02378|M.leprae_Br4923 PGITAWVTGASALIADMHHSGDKSMIRITATSVIVILVTLLLVYRSFITV MAB_4310c|M.abscessus_ATCC_199 PGIKAHVAGTTVLNADTQVAGHQSMATMELVSVGVIIVMILFIYRSIVTM MSMEG_0463|M.smegmatis_MC2_155 PGIKAHVAGTTVLNADTSVAGHQSMARMELISVAVIILMLLAIYRSIVTM MAV_4755|M.avium_104 PGVKAYVAGNTVLNADTSIVGHKSMATMALVSIVVIFVMLLVVYRSIVTT *: . *:* : : ** *. *: : :. ** :* ::**. * Mflv_4418|M.gilvum_PYR-GCK VLILFMVFAELGAARGIVAFLADAEIIGLSTFATSLLTLMVIAAGTDYAI Mvan_1936|M.vanbaalenii_PYR-1 VLILFMVFAELGAARGIVAFLANAEIIGLSTFATSLLTLMVIAAGTDYAI TH_3260|M.thermoresistible__bu LIALFMVLIGLLTTRGVVAFLGYHNIIGLSTFATSLLVTLAIAIAVDYAI MUL_0757|M.ulcerans_Agy99 AIMLTMVVLGLLATRGGVAFLGYHRIIGLSTFATNLLVVLAIAAATDYAI MMAR_0775|M.marinum_M ISVLVMVGIELMAARGVVAFLADNNVIGLSTFAVNLLVLMAIAAGTDYAI Mb0458c|M.bovis_AF2122/97 VLLLITVGVELTAARGVVAVLGHSGAIGLTTFAVSLLTSLAIAAGTDYGI Rv0450c|M.tuberculosis_H37Rv VLLLITVGVELTAARGVVAVLGHSGAIGLTTFAVSLLTSLAIAAGTDYGI MLBr_02378|M.leprae_Br4923 ILLLFTVGIESAVARGVVALLGHTGLIGLSTFAVNLLTSLAIAAGTDYGI MAB_4310c|M.abscessus_ATCC_199 LISMVIIGLELFAAQGVTATAGYLNVIGLTPYAVSMVTMLALAAGTDYVI MSMEG_0463|M.smegmatis_MC2_155 LISMVIIGLELFAAQSVTATAGHFNLIGLTPYAVSMTTMLALAAGTDYVI MAV_4755|M.avium_104 VLSLVIIGIELFAAQGITATAGNLNIIGLTPYAVSMITMLSIAAGTDYVI : : .::. .* . ***:.:*..: . : :* ..** * Mflv_4418|M.gilvum_PYR-GCK FAIGRYQEARGAGEDRETAYYTMFRGTAHVVLGSGLTIAGAMLCLSFTRL Mvan_1936|M.vanbaalenii_PYR-1 FAIGRYQEARGAGEDRETAYYTMFRGTAHVVLGSGLTIAGAMLCLSFTRL TH_3260|M.thermoresistible__bu FLIGRYQEARSVGADRATAYHTMFGGTAHVILASGLTIAGATFCLSFTRL MUL_0757|M.ulcerans_Agy99 FLIGRYQEARGLGQDRESAYYTMFGGTAHVVLGSGLTIAGATFCLSFTRL MMAR_0775|M.marinum_M FVLGRYQEARGEGESREKAFYTMFHGTAHVVLGSGLTIAGAMYCLSFTRL Mb0458c|M.bovis_AF2122/97 FIIGRYQEARQAGEDKEAAYYTMYRGTAHVILGSGLTITGATFCLSFARM Rv0450c|M.tuberculosis_H37Rv FIIGRYQEARQAGEDKEAAYYTMYRGTAHVILGSGLTIAGATFCLSFARM MLBr_02378|M.leprae_Br4923 FITGRYQEARQANENKEAAFYTMYRGTFHVILGSGLTISGATFCLSFARM MAB_4310c|M.abscessus_ATCC_199 FLFGRYHEERSKGLSREDAYYVAYHGVSHVILGSGLTIVGACLCLTMTTL MSMEG_0463|M.smegmatis_MC2_155 FLLGRYHEERSRGLDREEAYYVAYRGVSHVILGSGLTIAGACLCLTMTTL MAV_4755|M.avium_104 FLLGRYHEARSFGQGREEAFYTAYHGVSHVILGSGLTIAGACLCLTAARL * ***:* * . .: *::. : *. **:*.***** ** **: : : Mflv_4418|M.gilvum_PYR-GCK PYFQTMGVPCAVGTFVAVIAALTLGPAVIVIGSRFG-LFDPKRAISSRGW Mvan_1936|M.vanbaalenii_PYR-1 PYFQTMGVPCAVGTFVAVMAALTLGPAVVAIGSRFG-LFDPKRAISSRGW TH_3260|M.thermoresistible__bu PYFQSLGPPLAIGMIVLIVTSLTMGPAIITVATRFG-LLEPKRAARVRFW MUL_0757|M.ulcerans_Agy99 PYFQTLGVPLAIGMVIVVATALTLGPALIAVMSRFGKLLEPKRMARVRGW MMAR_0775|M.marinum_M PYFQTLGAPCAVGMLVAVLAALTLGPAVLVVGSFFK-LFDPKRKMRTRGW Mb0458c|M.bovis_AF2122/97 PYFQTLGIPCAVGMLVAVAVALTLGPAVLHVGSRFG-LFDPKRLLKVRGW Rv0450c|M.tuberculosis_H37Rv PYFQTLGIPCAVGMLVAVAVALTLGPAVLHVGSRFG-LFDPKRLLKVRGW MLBr_02378|M.leprae_Br4923 PYFQTLGVPCAVGMLIAVAVALTLGPAVLTVGSRFG-LFEPKRLIKVRGW MAB_4310c|M.abscessus_ATCC_199 PYFQSMALPCAISVLVIVAAALTLAPAVLTVASKFG-LLEPRGKLSTTGW MSMEG_0463|M.smegmatis_MC2_155 PYFQSMALPCAISILVIVIAALTLAPAVLTVASRFG-LLDPKRELSTKSW MAV_4755|M.avium_104 PYFQTMGLPCAIAMVVIVLAALTLAPAILAVGSRFG-LFDPKRAIDVRGW ****::. * *:. .: : .:**:.**:: : : * *::*: * Mflv_4418|M.gilvum_PYR-GCK RRIGVSVVRWPGPVLAATLALALVGLVTLPGYKTNYDARDYLPEDIPANV Mvan_1936|M.vanbaalenii_PYR-1 RRIGVSVVRWPGPVLAATLALALVGLVALPGYKTNYDSRDYLPEDVPANV TH_3260|M.thermoresistible__bu RKVGASVVRWPGPIMVTTVAVTLVGLLALPGYRTNYNDRNYLPASFPSNA MUL_0757|M.ulcerans_Agy99 RKIGAAIVRWPGPILIGAVALALVGLLTLPGYKTNYNDRNYLPADLPANE MMAR_0775|M.marinum_M RRVGTAIVRWPGPILAVSIAIALIGLLALPGYRTNYDSKKYLPASTPTNV Mb0458c|M.bovis_AF2122/97 RRVGTVVVRWPLPVLVATCAIALVGLLALPGYKTSYNDRDYLPDFIPANQ Rv0450c|M.tuberculosis_H37Rv RRVGTVVVRWPLPVLVATCAIALVGLLALPGYKTSYNDRDYLPDFIPANQ MLBr_02378|M.leprae_Br4923 RRIGTVVVRWPLPILITTCAIAMVGLLALPGYRTNYKDRAYLPASIPANQ MAB_4310c|M.abscessus_ATCC_199 RKVGTSVVRWPIPIIVLTSLIAIIGFVSLMTYVPQYNDQKFTPADMPANL MSMEG_0463|M.smegmatis_MC2_155 RKVGTAVVRWPIPIILVTGLVAAIGFASLLTYVPQYNDQKFTPADMPANV MAV_4755|M.avium_104 RKVGTAVVRWPKPIIVVTAAIAVIGFISLLTYVPNYDDQKFTPKDMPANA *::*. :**** *:: : :: :*: :* * ..*. : : * *:* Mflv_4418|M.gilvum_PYR-GCK GYAVADQHFGSARMNPELLMVESDHDLRNPADFLVIDKIAKSVFRVPGVA Mvan_1936|M.vanbaalenii_PYR-1 GYAVADRHFGSARMNPELLMVESDHDLRNPADFLVIDKIAKAIFRVPGVA TH_3260|M.thermoresistible__bu GYEAAERHFDPARLNPELLLIESDHDLRNPADFLVIEKIAKAVFQVEGIS MUL_0757|M.ulcerans_Agy99 GYSAAERHFSQARMNPEVLMVESDHDMRNSSDFLVINKIAKAIFGVEGIS MMAR_0775|M.marinum_M GYTAADRHFSQARMNPELLMVETDHDMRNPADMLVIDRIAKGVFHLPGVA Mb0458c|M.bovis_AF2122/97 GYAAADRHFSQARMKPEILMIESDHDMRNPADFLVLDKLAKGIFRVPGIS Rv0450c|M.tuberculosis_H37Rv GYAAADRHFSQARMKPEILMIESDHDMRNPADFLVLDKLAKGIFRVPGIS MLBr_02378|M.leprae_Br4923 GFAAADRHFPQARMKPEILMIESDHDMRNPADFLILDKLARGIFRVPGIS MAB_4310c|M.abscessus_ATCC_199 AMEVADRHFSQARMNPELLMLEADHDLRTPADMLVIDRVAKGIVHMRGIE MSMEG_0463|M.smegmatis_MC2_155 AMAVADRHFSEARMNPELLMLEADHDIRNPADMLVIDRVAKYVVHMRGIE MAV_4755|M.avium_104 AMTAAERHFSQARMNPELLMVEADHDLRDPADMLVVDRIAKSVFHLRGIE . .*::** **::**:*::*:***:* .:*:*:::::*: :. : *: Mflv_4418|M.gilvum_PYR-GCK RVQTITRPDGKPIKHTTIPFQMSMQGTTQRLNEKYLQDRMADMLVQADAM Mvan_1936|M.vanbaalenii_PYR-1 RVQTITRPDGKPIKHTTIPFQMSMRSTTSRLNEKYMQDRMADMLVQADAM TH_3260|M.thermoresistible__bu RVQGITRPEGTPIEHSSIPFMISQQGTLQILNQQYMQDRMADMLVQADEM MUL_0757|M.ulcerans_Agy99 RVQAITRPDGKPIEHTSIPFLISMQGTSQKLTEKYNQDLTTSMLQQVNDI MMAR_0775|M.marinum_M RVQAVTRPLGKPIEHSSIPFQISMQNTVQVENMQYMKQRMADMLIQAAAM Mb0458c|M.bovis_AF2122/97 RVQAITRPEGTTMDHTSIPFQISMQNAGQLQTIKYQRDRANDMLKQADEM Rv0450c|M.tuberculosis_H37Rv RVQAITRPEGTTMDHTSIPFQISMQNAGQLQTIKYQRDRANDMLKQADEM MLBr_02378|M.leprae_Br4923 RVQAITRPDGTAMDHTSIPFQISMQNAGQVQTMKYQKDRMNDLLRQAENM MAB_4310c|M.abscessus_ATCC_199 RVQTITRPLGAPIEHSSIPFLMGAQNAGTLQTAKFNNENSAQMLEQADEL MSMEG_0463|M.smegmatis_MC2_155 RVQTITRPLGSPIEHSSIPFLLGAQNAGTMQAAKFNNDNTAQMLEQADEL MAV_4755|M.avium_104 RVQTITRPLGAPIEHSSIPFQIAMQNSGTLQTAKFMNDTMANMLEQADEL *** :*** * .:.*::*** :. :.: :: .: .:* *. : Mflv_4418|M.gilvum_PYR-GCK QTNVDTMTRMQSLMGQMSATTHEMVLKTKKTEIDIIEVRDNLADFDDFFR Mvan_1936|M.vanbaalenii_PYR-1 QTNVDTMTKMQSLMTQMSAATHDMVTKTKKTAVDIVEVRDYLANLDDFVR TH_3260|M.thermoresistible__bu QLMIDTMDKMIALMEEMVETTDNMVRDMDEMAAHVAEMRDSISEFDDFFR MUL_0757|M.ulcerans_Agy99 QTNIDQMERMHDLTQQMADVTHQMVIQMKGMVVDVEELRNHIADFDDFFR MMAR_0775|M.marinum_M QDSIDTLDRMYDIMGKMVETTHDMDGLTHDMVEITDELRDHIADFDDFWR Mb0458c|M.bovis_AF2122/97 ATTIAVLTRMHSLMAEMASTTHRMVGDTEEMKEITEELRDHVADFDDFWR Rv0450c|M.tuberculosis_H37Rv ATTIAVLTRMHSLMAEMASTTHRMVGDTEEMKEITEELRDHVADFDDFWR MLBr_02378|M.leprae_Br4923 AETIASMRRMHQLMALLTENTHHILNDTVEMQKTTSKLRDEIANFDDFWR MAB_4310c|M.abscessus_ATCC_199 SRTVASMERMYSLMQELTGTMHSMVGRTHEMEATIQEMRDNLANFDDFFR MSMEG_0463|M.smegmatis_MC2_155 SRTIASMERMYGLTQELTDTTHSMVGRTHDMVEATKEMRDSLADFDDFFR MAV_4755|M.avium_104 DKTIAVMEHMYGVMKELTATTHSMVGRTHEMVDTTNELRDRIADFDDFFR : : :* : : . : ::*: ::::*** * Mflv_4418|M.gilvum_PYR-GCK PVRNYFYWEPHCYDIPVCWTMRSVFDTLDGINPLTDDISELIPDLERLDE Mvan_1936|M.vanbaalenii_PYR-1 PVRNYFYWEPHCYNIPVCATMRSVFDTLDGINPLTDDIQELIPDLERLDA TH_3260|M.thermoresistible__bu PIRNYFYWEPHCYNIPVCWAMRSVFDTLDGINTMTDDIQNMLPHMHRLND MUL_0757|M.ulcerans_Agy99 PIRSYFYWEKHCFDIPVCWSLRSVFDTLDGVDLMTEDINNLLPLMERLDT MMAR_0775|M.marinum_M PIRSYFYWEKHCYDVPICWSLRSIFDALDGVDKITEKLAALSRDMDRLDI Mb0458c|M.bovis_AF2122/97 PIRSYFYWEKHCYGIPICWSFRSIFDALDGIDKLSEQIGVLLGDLREMDR Rv0450c|M.tuberculosis_H37Rv PIRSYFYWEKHCYGIPICWSFRSIFDALDGIDKLSEQIGVLLGDLREMDR MLBr_02378|M.leprae_Br4923 PIRSYFYWERHCFNIPICWSFRSIFDALDGVDQIDERLNSIVGDIKNMDL MAB_4310c|M.abscessus_ATCC_199 PLRNYFYWEKHCFDIPICQSLRSIFDVLDSVDVLADQMHGLIADMDHMDQ MSMEG_0463|M.smegmatis_MC2_155 PMRNYLYWEPHCYDIPVCQSLRSVFDTLDGIGQLTDEMQGLTIDMDRMDE MAV_4755|M.avium_104 PIRSYFYWEKHCFDIPVCWSMRSLFDALDGIDELSDQISGLTIDLDHMDR *:*.*:*** **:.:*:* ::**:**.**.:. : : : : : .:: Mflv_4418|M.gilvum_PYR-GCK LMPQLIALLPSQIETMRSMQAMMLRQYQTQKGQLDQNAAMSEDADAMGEA Mvan_1936|M.vanbaalenii_PYR-1 LMPQLIALLPSQIESMRNMQSMMLTMYQSQKGLQDQMASQSEDADAMGEA TH_3260|M.thermoresistible__bu LMPQMLTLLPTTVATMKTMRSMLLTMQATNAGLQDQMAEMQENANAMGEA MUL_0757|M.ulcerans_Agy99 LMPQMTAMMPEMIQTMKSMKAQMLSMHSTQQGLQDQMAAMQEDSSAMGEA MMAR_0775|M.marinum_M LMPQMRAQIPFQIASMKTMKTMMLTMHSSMSSLYDQMDEMSKNSTAMGKA Mb0458c|M.bovis_AF2122/97 LMPQMVAQIPPQIEAMENMRTMILTMHSTMTGIFDQMLEMSDNATAMGKA Rv0450c|M.tuberculosis_H37Rv LMPQMVAQIPPQIEAMENMRTMILTMHSTMTGIFDQMLEMSDNATAMGKA MLBr_02378|M.leprae_Br4923 LMPQMLEQFPPMIESMESMRTIMLTMHSTMSGIFDQMNELSDNANTMGKA MAB_4310c|M.abscessus_ATCC_199 LMPQMLPVLRTTIDSMGRMRDFMIATHSTMAGTQAQQQELAKGATEIGLY MSMEG_0463|M.smegmatis_MC2_155 LMPQMLPILRSTIDSMKTMRDFMIATHSVMAGTQAQQQELAKNATEIGLY MAV_4755|M.avium_104 LMPQLLADFPKTIDSMKTMRDFMLSTHSTMAGIQAHQQEAAEGSTLMGQY ****: : : :* *: :: . : ..: :* Mflv_4418|M.gilvum_PYR-GCK FDDSMNDDSFYLPPEAFDNDDFKRGMENFISPDGRSVRFIISHEGDPATV Mvan_1936|M.vanbaalenii_PYR-1 FDDSMNDDSFYLPPEAFDNDDFKRGIENFISPDGKSVRFIIAHEGDPATV TH_3260|M.thermoresistible__bu FDQARNDDSFYLPPEAFDNPDFQRGLEQFLSPDGHAVRFIISHQGDPMTP MUL_0757|M.ulcerans_Agy99 FDSSRNDDSFYLPPEVFNNPDFKRGLEQFLSPDGHAVRFIISHEGDPMSQ MMAR_0775|M.marinum_M FDAARNDDSFYIPPEVFDNADFKRGLKMFLSPDGHAVRFIISHEGDPAST Mb0458c|M.bovis_AF2122/97 FDAAKNDDSFYLPPEVFKNKDFQRAMKSFLSSDGHAARFIILHRGDPQSP Rv0450c|M.tuberculosis_H37Rv FDAAKNDDSFYLPPEVFKNKDFQRAMKSFLSSDGHAARFIILHRGDPQSP MLBr_02378|M.leprae_Br4923 FDTAKNDDSFYLPPEVFKNTDFKRAMKSFLSSDGHAARFIILHRGDPASV MAB_4310c|M.abscessus_ATCC_199 FDQAKNDDFFYLPPDVFTNPDFKRGLKMFVSPDGKAVRFIITHQGDPASV MSMEG_0463|M.smegmatis_MC2_155 FDQAKNDDFFYLPPDVFDNPDFKRGLEMFVSPDGKAVRMIITHQGDPASV MAV_4755|M.avium_104 FDEAKNDDSFYLPPEVFKNPDFKRGLKMFVSPDGTAVRFIITHQGDPASV ** : *** **:**:.* * **:*.:: *:*.** :.*:** *.*** : Mflv_4418|M.gilvum_PYR-GCK EGISEVVPIKTAAKEAIKGTPLEGSTVYLAGTAATYKDMSDGAFYDLLIA Mvan_1936|M.vanbaalenii_PYR-1 EGISRVLPIKTAAKEAIKGTPLEGSTVYLAGTAATYKDMRDGANYDLLIA TH_3260|M.thermoresistible__bu EGLAKIEPIKKAAVEAIKGTPLEGSRVYLGGTAAVFKDMSDGTKYDLIIA MUL_0757|M.ulcerans_Agy99 AGINHIDKIKTAAKEAIKGTPLEGSTIYLGGTVAMFKDLSDGNTFDLMIA MMAR_0775|M.marinum_M EGISHVKPIMDEAKQAIKGTPLEGAKIYLAGTASVYKDMRDGSRWDLLIA Mb0458c|M.bovis_AF2122/97 EGIKSIDAIRTAAEESLKGTPLEDAKIYLAGTAAVFHDISEGAQWDLLIA Rv0450c|M.tuberculosis_H37Rv EGIKSIDAIRTAAEESLKGTPLEDAKIYLAGTAAVFHDISEGAQWDLLIA MLBr_02378|M.leprae_Br4923 AGIASINAIRTAAEEALKGTPLEDTKIYLAGTAAVFKDIDEGANWDLVIA MAB_4310c|M.abscessus_ATCC_199 EGIDHVRDLKGVVADAVKGTPLSNAKVSIAGTASMYADMQDGVSIDLMIA MSMEG_0463|M.smegmatis_MC2_155 DGIAHVRDLRDVVADAVKGTPLANAKVSLAGTASLYSDMQDGVVTDLMIA MAV_4755|M.avium_104 EGIKHVAGVKDAVADAIKGTPLESSKVYLAGTASMYSDMQEGVIIDLLVA *: : : . :::***** .: : :.**.: : *: :* **::* Mflv_4418|M.gilvum_PYR-GCK GIAAVTLIFVIMLVITRSVVAAAVIVGTVLLSLGASFGLSVLLWQHIIGL Mvan_1936|M.vanbaalenii_PYR-1 GIAAVTLIFVIMLIITRSVVAAAVIVGTVLLSLGASFGLSVLLWQHIIGL TH_3260|M.thermoresistible__bu AIAAVCLIFIIMLILTRAVVAAAVIVGTVTLSLAASFGVSVLIWQYIVGL MUL_0757|M.ulcerans_Agy99 GISALCLIFIIMLIITRSVVAAAVIVGTVVLSLGASFGLSVLIWQHVLGI MMAR_0775|M.marinum_M GVAAVSLILIIMLIITRSLVAAVVIVGTVLLSLGASFGLSVLVWQDIFGV Mb0458c|M.bovis_AF2122/97 AISSLCLIFIIMLIITRAFIAAAVIVGTVALSLGASFGLSVLLWQHILAI Rv0450c|M.tuberculosis_H37Rv AISSLCLIFIIMLIITRAFIAAAVIVGTVALSLGASFGLSVLLWQHILAI MLBr_02378|M.leprae_Br4923 GISSLCLIFIIMLIITRAFVAAAVIVGTVALSLGASFGLSVLLWQHILGI MAB_4310c|M.abscessus_ATCC_199 VIASMILIFAIMVLITRSVVAALVIVGTVAASLGTACGLSVLLWQDILGL MSMEG_0463|M.smegmatis_MC2_155 IIASMILIFGIMLVITRSVVAALVIVGTVAASLGTACGLSVLLWQDILGL MAV_4755|M.avium_104 GISCLILIFTIMLIITRSVVAALVIVGTVAASLGTACGLSVLMWQDLIGL ::.: **: **:::**:.:** ****** **.:: *:***:** :..: Mflv_4418|M.gilvum_PYR-GCK ALHWMVLPMAVILLLAVGSDYNLLLVSRFKEELSGGLKTGIIRAMAGTGS Mvan_1936|M.vanbaalenii_PYR-1 ALHWMVLPMAVILLLAVGSDYNLLLVSRFKEELAGGLKTGIIRSMAGTGS TH_3260|M.thermoresistible__bu EMHWMVFPMALIILLAVGADYNLLVVARLREEIPAGLNTGMIRAMGGSGS MUL_0757|M.ulcerans_Agy99 ELHWLVLAMAVIILLAVGADYNLLLVARLKEEIHAGINTGIIRAMGGSGS MMAR_0775|M.marinum_M ELHWMVLAMSVILLLAVGSDYNLLLVSRLKEEIGAGLKTGIIRAMAGTGG Mb0458c|M.bovis_AF2122/97 HLHWLVLAMSVIVLLAVGSDYNLLLVSRFKQEIGAGLKTGIIRSMGGTGK Rv0450c|M.tuberculosis_H37Rv HLHWLVLAMSVIVLLAVGSDYNLLLVSRFKQEIGAGLKTGIIRSMGGTGK MLBr_02378|M.leprae_Br4923 ELHYLVLAMSVIVLLAVGSDYNLLLVSRFKQEIQAGLKTGIIRSMGGTGK MAB_4310c|M.abscessus_ATCC_199 GVQWIVIPLSMVILLAVGSDYNLLVVSRLKEEIHAGLNTGMIRGMGATGR MSMEG_0463|M.smegmatis_MC2_155 GVQWVVLPLSIVILLAVGSDYNLLLVSRLKEEIHAGLNTGIIRGMGATGR MAV_4755|M.avium_104 GVQWIVLPLSIVILLAVGSDYNLLLVSRLKEEIPAGLNTGIIRGMGASGR ::::*:.:::::*****:*****:*:*:::*: .*::**:**.*..:* Mflv_4418|M.gilvum_PYR-GCK VVTSAGLVFAFTMASFAFSDLKVMAQVGTTIALGLLFDTLIVRSFMTPAV Mvan_1936|M.vanbaalenii_PYR-1 VVTSAGLVFAFTMASFAFSDLKVMAQVGTTIALGLLFDTLIVRSFMTPAV TH_3260|M.thermoresistible__bu VVTAAGLVFGLTMMVMVVSDLTVMGQVGTTIGLGLLFDTFVVRSFMMPSI MUL_0757|M.ulcerans_Agy99 VVTAAGLVFAFTMMSFAVSELTVMAQVGTTIGMGLLFDTLIVRSFMTPSI MMAR_0775|M.marinum_M VVTTAGLVFAATMASFIFSDLRVIGQVGTTIGLGLLFDTLIVRSFMTPSI Mb0458c|M.bovis_AF2122/97 VVTNAGLVFAVTMASMAVSDLRVIGQVGTTIGLGLLFDTLIVRSFMTPSI Rv0450c|M.tuberculosis_H37Rv VVTNAGLVFAVTMASMAVSDLRVIGQVGTTIGLGLLFDTLIVRSFMTPSI MLBr_02378|M.leprae_Br4923 VVTNAGLVFAFTMASMVVSDLRVIGQVGTTIGLGLLFDTLIVRSFMMPSI MAB_4310c|M.abscessus_ATCC_199 VVTAAGLVFAFTMMSMIVSDLRVVGQLGMTIGIGLIVDTLIVRAFMTPSI MSMEG_0463|M.smegmatis_MC2_155 VVTAAGLVFAFTMMAMIVSDLRVVGQLGTTIGLGLIVDTLIVRAFMTPSI MAV_4755|M.avium_104 VVTAAGLVFAFTMASMIVSQLRVIGELGTTIALGLLVDTLIVRSFMTPSI *** *****. ** : .*:* *:.::* **.:**:.**::**:** *:: Mflv_4418|M.gilvum_PYR-GCK AALLGRWFWWPQKFRSAASERRLARIGVQPATAGR--------------- Mvan_1936|M.vanbaalenii_PYR-1 AALLGRWFWWPQKVRSHASQRRLAALNH---------------------- TH_3260|M.thermoresistible__bu ATLLGRWFWWPQFVRKRPVPQPWPSVPPRGPATTDRVSV----------- MUL_0757|M.ulcerans_Agy99 AALLGKWFWWPQVVRQRPAPQPWPTPAPTPPPATTSV------------- MMAR_0775|M.marinum_M AALMGRWFWWPQQVRTRPASQLLRPYGPRPLVRALLLPRNGDSADGPEDT Mb0458c|M.bovis_AF2122/97 AALLGRWFWWPLRVRSRPARTPTVPSETQPAGRPLAMSSDRLG------- Rv0450c|M.tuberculosis_H37Rv AALLGRWFWWPLRVRSRPARTPTVPSETQPAGRPLAMSSDRLG------- MLBr_02378|M.leprae_Br4923 AALLGRWFWWPQQGRTRPLLTVAAPVGLPPD-RSLVYSD----------- MAB_4310c|M.abscessus_ATCC_199 AAALGRWFWWPINVFEIVRRGRETQAPEPVTAPLPVVDAGPQPPTAPSTS MSMEG_0463|M.smegmatis_MC2_155 AAALGRWFWWPLNTFEITRRGR--QAPHARS-----VDGNTQPFPGVTTA MAV_4755|M.avium_104 AAALGHWFWWPINTIRMTRRTHHDEEAHTAP--------IRQPALR---- *: :*:***** Mflv_4418|M.gilvum_PYR-GCK ------------ Mvan_1936|M.vanbaalenii_PYR-1 ------------ TH_3260|M.thermoresistible__bu ------------ MUL_0757|M.ulcerans_Agy99 ------------ MMAR_0775|M.marinum_M NTERLAVSSPHY Mb0458c|M.bovis_AF2122/97 ------------ Rv0450c|M.tuberculosis_H37Rv ------------ MLBr_02378|M.leprae_Br4923 ------------ MAB_4310c|M.abscessus_ATCC_199 ------------ MSMEG_0463|M.smegmatis_MC2_155 P----------- MAV_4755|M.avium_104 ------------