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VSASQDEPANRLERRKQRTRAALIQAAQALIAEGKLNVPVLEITQAADVGMGSFYNHFDSKEALFDAAVA DVLDNHGALLDRLTESIDDPAETFACSFRLTGRLFRRRPQESQILLVNGLSLIGSDRGLGPRALRDITAG VAAGRFTVDDSKLALAVAAGALLGLGKLLQQEPERDDATAADRVTEDVLRLLGLPAEEARQICKRPLPSL DGASEHD
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_2577 | - | - | 100% (217) | TetR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_0647 | - | 7e-09 | 38.20% (89) | transcriptional regulator TetR |
| M. abscessus ATCC 19977 | MAB_0483c | - | 2e-06 | 43.94% (66) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0068c | - | 6e-09 | 41.89% (74) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_4816 | - | 8e-06 | 45.28% (53) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0067c | - | 6e-09 | 41.89% (74) | TetR family transcriptional regulator |
| M. leprae Br4923 | MLBr_00316 | - | 5e-08 | 38.03% (71) | putative TetR/AcrR-family transcriptional regulator |
| M. marinum M | MMAR_2984 | - | 2e-85 | 76.08% (209) | TetR family transcriptional regulator |
| M. avium 104 | MAV_1801 | - | 3e-83 | 72.60% (208) | TetR-family protein transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_5673 | - | 2e-08 | 28.57% (189) | transcriptional regulator |
| M. thermoresistible (build 8) | TH_2855 | - | 6e-10 | 31.55% (206) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_4876 | - | 1e-06 | 28.03% (157) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_4909 | - | 3e-72 | 62.91% (213) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MAB_2577|M.abscessus_ATCC_1997 -------------------------MSASQ---DEPANRLERRKQRTR--
MMAR_2984|M.marinum_M -------------------------MTTSDRGAPAQANRSERRKRRTR--
MAV_1801|M.avium_104 --------------------------MAADLADGVTPNRLERRKQRTR--
Mvan_4909|M.vanbaalenii_PYR-1 ---------------------MNEAHRDAHAASTAPVSRLQRRKMRTR--
Mb0068c|M.bovis_AF2122/97 --------------------------------MAPTDRRVRADAARNR--
Rv0067c|M.tuberculosis_H37Rv --------------------------------MAPTDRRVRADAARNR--
MLBr_00316|M.leprae_Br4923 ---------------------MSVPRSGLSVQMAQPARPLRADAARNR--
MUL_4876|M.ulcerans_Agy99 ------------------------MTVPTFSTRSQLGRPVGARGEQTR--
TH_2855|M.thermoresistible__bu -----------LSQSPDNATSSSRAGSGAGSGAGSGAEPIGRDTPRRRPR
Mflv_4816|M.gilvum_PYR-GCK MGSRQEISAACGRFHTVNSRTPSSRRGHSSRSRSKDGNSRETLSREERKE
MSMEG_5673|M.smegmatis_MC2_155 -----------------------------MAYQTQQPGLRERKKQRTR--
. *
MAB_2577|M.abscessus_ATCC_1997 ---AALIQAAQALIAEGK-LNVPVLEITQAADVGMGSFYNHFDSKEALFD
MMAR_2984|M.marinum_M ---TALLRAAQRLIAEGK-LNVPVLEITQAADVGMGSFYNHFDSKEQLFE
MAV_1801|M.avium_104 ---TALIRAAQAFIASGK-LNAPILEITQAADVGMGSFYNHFESKEELFE
Mvan_4909|M.vanbaalenii_PYR-1 ---MALIHAAQGFIAEGK-LAVPVLEITQAADVGMGSFYNHFDSKDELFE
Mb0068c|M.bovis_AF2122/97 ---ARVLEVAYQTFAADG-LSVPVDEIARRAGVGAGTVYRHFPTKEALFQ
Rv0067c|M.tuberculosis_H37Rv ---ARVLEVAYQTFAADG-LSVPVDEIARRAGVGAGTVYRHFPTKEALFQ
MLBr_00316|M.leprae_Br4923 ---ARILGVAYEAFATEG-LSVPIDEIARRAGVGAGTVYRHFPTKEALCA
MUL_4876|M.ulcerans_Agy99 ---QRIITAAMRCVAEAGPAQASIREIAKAADMTSGSLYHYFPNKSELLN
TH_2855|M.thermoresistible__bu IRPEEIVSAAAEFFAREGYANVGMRDVAEAVGIRGASLYHHFGSKEEILY
Mflv_4816|M.gilvum_PYR-GCK ATRRAIVDAALHLLAERGFSALSLREVTREAGIVPAAFYRHFDSMEALGL
MSMEG_5673|M.smegmatis_MC2_155 ---ATLISAAIDLCVRQGYEQTTVEQIAAAAEVSARTFSRYFATKDAVML
:: .* . : ::: . : :. .:* . . :
MAB_2577|M.abscessus_ATCC_1997 AAVADVLDNHGALLDRLTESIDDPAETFACSFRLTGRLFRRR-------P
MMAR_2984|M.marinum_M AAVADVLDAHGALLDRCTASIEDPAETFAASFRLTGRLFRRR-------P
MAV_1801|M.avium_104 AAVAEVLDAHGALLDQLVADLDDPAEKFACSFRLTGRFFRRR-------P
Mvan_4909|M.vanbaalenii_PYR-1 AAVTEALDGFGALLDSYTAAVADPAEAFATSFRLSGRLFRIR-------P
Mb0068c|M.bovis_AF2122/97 AVIADRMH-----------RIIDKGHALLKSKHPGDALFAFL-------R
Rv0067c|M.tuberculosis_H37Rv AVIADRMH-----------RIIDKGHALLKSKHPGDALFAFL-------R
MLBr_00316|M.leprae_Br4923 AVIGDRMP-----------HLVDDGYVLLKSAGPGEALFTYL-------R
MUL_4876|M.ulcerans_Agy99 ATATEIEEIVLPRLHAAAASSDDIVDRLDAVLDESKRLMRDY-------P
TH_2855|M.thermoresistible__bu AICLTVTKEPNELNLPLLDAAGTPAERLSALIRAHLEHLIRRRVEHLVAL
Mflv_4816|M.gilvum_PYR-GCK VLIDESFRSLREMLRGARAGKLDPNRVIESSVDILIDGVQQR-------R
MSMEG_5673|M.smegmatis_MC2_155 AFLDDVVDLVAGELAQQPPELGELDAVFCAHITAFEKTRVAMPG-----Q
. :
MAB_2577|M.abscessus_ATCC_1997 QESQILLVNGLSLIGSDRGLGPRALRDITAG--VAAGRFTVDDSKLA--L
MMAR_2984|M.marinum_M QESEILLANGAALLSSDRGLAPRALRDIKAA--SDAGRFRVEDPELA--L
MAV_1801|M.avium_104 EESKVLLANGLSLMSSDRGLAPRALRDIKDA--IEAGRFRVDDPRLA--L
Mvan_4909|M.vanbaalenii_PYR-1 QEAKLLLANGSSLILSEHGLSPRALRDITAA--IDKGRFKITDPELG--L
Mb0068c|M.bovis_AF2122/97 SMVLQWGATDRGLVEALAGVG-IEISSAAPE--AEADFLDLLTDLLR--A
Rv0067c|M.tuberculosis_H37Rv SMVLQWGATDRGLVEALAGVG-IEISSAAPE--AEADFLDLLTDLLR--A
MLBr_00316|M.leprae_Br4923 SLVLHWGATDRGLVDALAGAGGIDILGVAPD--AEDAFLTILSDLLY--A
MUL_4876|M.ulcerans_Agy99 YLAGFLRAVR-AENADQTGGGRRTYPGSKAL--RDVITEIVDDARGR--G
TH_2855|M.thermoresistible__bu HDINSLTPEHRAIIDDLRRYYQRRVRDVIVAG-VRSGEFDVPDPKLA--A
Mflv_4816|M.gilvum_PYR-GCK EHWRFIGRERSTGVTVLRYAIRTEIRLITSELAIDLARFPALNTWSSEDL
MSMEG_5673|M.smegmatis_MC2_155 LTDDRLLAAARIFTSSPSLMQATMGFRPAPLFEVLAKRMGVSADDRK--I
MAB_2577|M.abscessus_ATCC_1997 AVAAGALLGLGKLLQQEPERDDATAADRVTEDVLRLLGLPAEEARQICKR
MMAR_2984|M.marinum_M AMAGGALLGLGTLLRADPQRDGCAAADAVTEDLLRLFGLDAEQARAICRR
MAV_1801|M.avium_104 AVAGGALMGLGQLLHDEPSRDDELATDQVTASVLRLFGLRANEADKICRR
Mvan_4909|M.vanbaalenii_PYR-1 AIAAGALYGLGTLLTQRPDRDGASATDEVTASVLRMFGMTSQQARGLCRH
Mb0068c|M.bovis_AF2122/97 AQRAGTVR-------------PDVDVLEVKTLLVGCQAMQSYNAELAAKV
Rv0067c|M.tuberculosis_H37Rv AQRAGTVR-------------PDVDVLEVKTLLVGCQAMQSYNAELAAKV
MLBr_00316|M.leprae_Br4923 AQYAGTAR-------------TDVGVREVKSILVGCQAMEAYNSALAERV
MUL_4876|M.ulcerans_Agy99 VLSAGIAPG---AAVDAICALTRGLTEQAANLGPQSYDVTLDSAKQLLRG
TH_2855|M.thermoresistible__bu LLILDALNG--------------VSGWFHPDRGHSLPDVIAAYTEMIVER
Mflv_4816|M.gilvum_PYR-GCK NILASVFVN------------SMIAIAEQLEDVTDTASVDEIRRTAVKQL
MSMEG_5673|M.smegmatis_MC2_155 ALIASLWNA------------IMTTALVQLVPDVDWATVTVERIVNQMRT
. : .
MAB_2577|M.abscessus_ATCC_1997 PLPSLDGASEHD-------------
MMAR_2984|M.marinum_M PLPDLDGWDQPDSAA----------
MAV_1801|M.avium_104 PLPEIDGLTRPDSAA----------
Mvan_4909|M.vanbaalenii_PYR-1 PLPDLSSLQDTRAARPTPIPPAGVT
Mb0068c|M.bovis_AF2122/97 TDVALDGLRANRK------------
Rv0067c|M.tuberculosis_H37Rv TDVALDGLRANRK------------
MLBr_00316|M.leprae_Br4923 TDVVVDGLRAAR-------------
MUL_4876|M.ulcerans_Agy99 SLFAGAKPTATRRT-----------
TH_2855|M.thermoresistible__bu VLRARIS------------------
Mflv_4816|M.gilvum_PYR-GCK RMITVGVAGWRSG------------
MSMEG_5673|M.smegmatis_MC2_155 TYAEFLEVAGRRHEFA---------