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AADLADGVTPNRLERRKQRTRTALIRAAQAFIASGKLNAPILEITQAADVGMGSFYNHFESKEELFEAAV AEVLDAHGALLDQLVADLDDPAEKFACSFRLTGRFFRRRPEESKVLLANGLSLMSSDRGLAPRALRDIKD AIEAGRFRVDDPRLALAVAGGALMGLGQLLHDEPSRDDELATDQVTASVLRLFGLRANEADKICRRPLPE IDGLTRPDSAA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_1801 | - | - | 100% (222) | TetR-family protein transcriptional regulator |
| M. avium 104 | MAV_1948 | - | 2e-07 | 36.14% (83) | putative transcriptional regulator |
| M. avium 104 | MAV_2650 | - | 1e-06 | 36.14% (83) | putative transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0068c | - | 3e-07 | 35.06% (77) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_1483 | - | 1e-06 | 27.03% (148) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0067c | - | 3e-07 | 35.06% (77) | TetR family transcriptional regulator |
| M. leprae Br4923 | MLBr_00316 | - | 2e-05 | 34.25% (73) | putative TetR/AcrR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_2577 | - | 3e-83 | 72.60% (208) | TetR family transcriptional regulator |
| M. marinum M | MMAR_2984 | - | 3e-85 | 73.46% (211) | TetR family transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_0878 | - | 9e-07 | 39.53% (86) | transcriptional regulator |
| M. thermoresistible (build 8) | TH_2855 | - | 8e-10 | 29.23% (195) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_4876 | - | 2e-07 | 29.94% (157) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_4909 | - | 1e-71 | 63.38% (213) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MAB_2577|M.abscessus_ATCC_1997 --------------MSASQ---DEPANRLERRKQRTR-----AALIQAAQ
MMAR_2984|M.marinum_M --------------MTTSDRGAPAQANRSERRKRRTR-----TALLRAAQ
MAV_1801|M.avium_104 ---------------MAADLADGVTPNRLERRKQRTR-----TALIRAAQ
Mvan_4909|M.vanbaalenii_PYR-1 ----------MNEAHRDAHAASTAPVSRLQRRKMRTR-----MALIHAAQ
Mb0068c|M.bovis_AF2122/97 ---------------------MAPTDRRVRADAARNR-----ARVLEVAY
Rv0067c|M.tuberculosis_H37Rv ---------------------MAPTDRRVRADAARNR-----ARVLEVAY
MLBr_00316|M.leprae_Br4923 ----------MSVPRSGLSVQMAQPARPLRADAARNR-----ARILGVAY
MSMEG_0878|M.smegmatis_MC2_155 ---------------------MS-----MRADAARNR-----ARVLEVAY
MUL_4876|M.ulcerans_Agy99 -------------MTVPTFSTRSQLGRPVGARGEQTR-----QRIITAAM
TH_2855|M.thermoresistible__bu LSQSPDNATSSSRAGSGAGSGAGSGAEPIGRDTPRRRPRIRPEEIVSAAA
Mflv_1483|M.gilvum_PYR-GCK ----------------------------MDRALPSRR-----DELLQLAA
* :: *
MAB_2577|M.abscessus_ATCC_1997 ALIAEGK-LNVPVLEITQAADVGMGSFYNHFDSKEALFDAAVADVLDNHG
MMAR_2984|M.marinum_M RLIAEGK-LNVPVLEITQAADVGMGSFYNHFDSKEQLFEAAVADVLDAHG
MAV_1801|M.avium_104 AFIASGK-LNAPILEITQAADVGMGSFYNHFESKEELFEAAVAEVLDAHG
Mvan_4909|M.vanbaalenii_PYR-1 GFIAEGK-LAVPVLEITQAADVGMGSFYNHFDSKDELFEAAVTEALDGFG
Mb0068c|M.bovis_AF2122/97 QTFAADG-LSVPVDEIARRAGVGAGTVYRHFPTKEALFQAVIADRMH---
Rv0067c|M.tuberculosis_H37Rv QTFAADG-LSVPVDEIARRAGVGAGTVYRHFPTKEALFQAVIADRMH---
MLBr_00316|M.leprae_Br4923 EAFATEG-LSVPIDEIARRAGVGAGTVYRHFPTKEALCAAVIGDRMP---
MSMEG_0878|M.smegmatis_MC2_155 EAFAQDG-LAVPIDEIARRAGVGAGTVYRHFPSKEDLYRAVVAERIR---
MUL_4876|M.ulcerans_Agy99 RCVAEAGPAQASIREIAKAADMTSGSLYHYFPNKSELLNATATEIEEIVL
TH_2855|M.thermoresistible__bu EFFAREGYANVGMRDVAEAVGIRGASLYHHFGSKEEILYAICLTVTK---
Mflv_1483|M.gilvum_PYR-GCK TMFADRGLRATTVRDIADSAGILSGSLYHHFKSKEQMVEEVLKDFLD---
.* . : ::: ..: .:.*.:* .*. :
MAB_2577|M.abscessus_ATCC_1997 ALLDRLTESIDDPAETFACSFRLTGRLFRRRPQESQILLVNGLSLIGSDR
MMAR_2984|M.marinum_M ALLDRCTASIEDPAETFAASFRLTGRLFRRRPQESEILLANGAALLSSDR
MAV_1801|M.avium_104 ALLDQLVADLDDPAEKFACSFRLTGRFFRRRPEESKVLLANGLSLMSSDR
Mvan_4909|M.vanbaalenii_PYR-1 ALLDSYTAAVADPAEAFATSFRLSGRLFRIRPQEAKLLLANGSSLILSEH
Mb0068c|M.bovis_AF2122/97 --------RIIDKGHALLKSKHPGDALFAFLRSMVLQWGATDRGLVEALA
Rv0067c|M.tuberculosis_H37Rv --------RIIDKGHALLKSKHPGDALFAFLRSMVLQWGATDRGLVEALA
MLBr_00316|M.leprae_Br4923 --------HLVDDGYVLLKSAGPGEALFTYLRSLVLHWGATDRGLVDALA
MSMEG_0878|M.smegmatis_MC2_155 --------EIVDQGQALLADGDPGEALFDYLRLMVLQCGAADRGLVEALA
MUL_4876|M.ulcerans_Agy99 PRLHAAAASSDDIVDRLDAVLDESKRLMRDYPYLAGFLRAVR-AENADQT
TH_2855|M.thermoresistible__bu -------EPNELNLPLLDAAGTPAERLSALIRAHLEHLIRRRVEHLVALH
Mflv_1483|M.gilvum_PYR-GCK ----WLFTRYDEIVAATTDPLERVSGLFMVSFEAIEHRHAQVVIYQDEAK
:
MAB_2577|M.abscessus_ATCC_1997 GLGPRALRDITAGVAAGRFTVDDSKLALAVAAGALLGLGKLLQQEPERDD
MMAR_2984|M.marinum_M GLAPRALRDIKAASDAGRFRVEDPELALAMAGGALLGLGTLLRADPQRDG
MAV_1801|M.avium_104 GLAPRALRDIKDAIEAGRFRVDDPRLALAVAGGALMGLGQLLHDEPSRDD
Mvan_4909|M.vanbaalenii_PYR-1 GLSPRALRDITAAIDKGRFKITDPELGLAIAAGALYGLGTLLTQRPDRDG
Mb0068c|M.bovis_AF2122/97 GVG-IEISSAAPEAEADFLDLLTDLLRAAQRAGTVR-------------P
Rv0067c|M.tuberculosis_H37Rv GVG-IEISSAAPEAEADFLDLLTDLLRAAQRAGTVR-------------P
MLBr_00316|M.leprae_Br4923 GAGGIDILGVAPDAEDAFLTILSDLLYAAQYAGTAR-------------T
MSMEG_0878|M.smegmatis_MC2_155 GAG-IDVKTMVPDAEDEYMEMLGGLLRAAQRAGTVR-------------G
MUL_4876|M.ulcerans_Agy99 GGGRRTYPGSKALRDVITEIVDDARGRGVLSAGIAPG--------AAVDA
TH_2855|M.thermoresistible__bu DIN--SLTPEHRAIIDDLRRYYQRRVRDVIVAGVRSG------EFDVPDP
Mflv_1483|M.gilvum_PYR-GCK RLNSLPQFGFLDDRNRQQRRMWVEVLKQGIAEGSFR---------PDIDV
*
MAB_2577|M.abscessus_ATCC_1997 ATAADRVTEDVLRLLGLPAEEARQICKRPLPSLDGASEHD----------
MMAR_2984|M.marinum_M CAAADAVTEDLLRLFGLDAEQARAICRRPLPDLDGWDQPDSAA-------
MAV_1801|M.avium_104 ELATDQVTASVLRLFGLRANEADKICRRPLPEIDGLTRPDSAA-------
Mvan_4909|M.vanbaalenii_PYR-1 ASATDEVTASVLRMFGMTSQQARGLCRHPLPDLSSLQDTRAARPTPIPPA
Mb0068c|M.bovis_AF2122/97 DVDVLEVKTLLVGCQAMQSYNAELAAKVTDVALDGLRANRK---------
Rv0067c|M.tuberculosis_H37Rv DVDVLEVKTLLVGCQAMQSYNAELAAKVTDVALDGLRANRK---------
MLBr_00316|M.leprae_Br4923 DVGVREVKSILVGCQAMEAYNSALAERVTDVVVDGLRAAR----------
MSMEG_0878|M.smegmatis_MC2_155 DVTATDVKALLVGCQAMQAYDATAAEHLTGVVFDGLRVAPASVPSR----
MUL_4876|M.ulcerans_Agy99 ICALTRGLTEQAANLGPQSYDVTLDSAKQLLRGSLFAGAKPTATRRT---
TH_2855|M.thermoresistible__bu KLAALLILDALNGVSGWFHPDRGHSLPDVIAAYTEMIVERVLRARIS---
Mflv_1483|M.gilvum_PYR-GCK DLVYRFIRDTTWVSVRWYQPGGPLTAEQVGRQYLAIVLGGITEGSK----
MAB_2577|M.abscessus_ATCC_1997 ---
MMAR_2984|M.marinum_M ---
MAV_1801|M.avium_104 ---
Mvan_4909|M.vanbaalenii_PYR-1 GVT
Mb0068c|M.bovis_AF2122/97 ---
Rv0067c|M.tuberculosis_H37Rv ---
MLBr_00316|M.leprae_Br4923 ---
MSMEG_0878|M.smegmatis_MC2_155 ---
MUL_4876|M.ulcerans_Agy99 ---
TH_2855|M.thermoresistible__bu ---
Mflv_1483|M.gilvum_PYR-GCK ---