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M. abscessus ATCC 19977 MAB_2571c (-)

annotation: MmpL family membrane protein
coordinates: 2615383 - 2616420
length: 345

HGDGSMTSGQQPPLPGDDADTGPVPVPTQRAMRHETHKHPAAARWLRVLAIPVVLFWVIAAAVLNIFVPS
LEETTAANAKAMIPRDAPSSAAAITQGQDFQESAYTSAAVIVLETQGRTLGEQDRQYYNKLVRGLLDDKE
HVQSLMDLWGDPVTRSGQQSADARAATLTVRPTGDLADADSNRSIKAIRGTVEKLDKEKPDGLRVYVSGP
APLASDTLTAADESMLMLTIVTIVVIIIMLLIAYRSFTRAIIPLVGVLITLATARGVVSLLVENHIIGIS
SFAMNMAVSLVLGVATDYGIFYLGRFQEALRSGRTVSRRTTPRCAASRTSSSDRVWRSRVRACA*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. abscessus ATCC 19977MAB_2571c--100% (345)MmpL family membrane protein
M. abscessus ATCC 19977MAB_0478-e-13983.77% (308) membrane protein MmpL
M. abscessus ATCC 19977MAB_3562c-1e-7245.76% (295) MmpL family protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0695cmmpL56e-5641.55% (296) transmembrane transport protein MmpL5
M. gilvum PYR-GCKMflv_2705-2e-5942.70% (274) transport protein
M. tuberculosis H37RvRv0676cmmpL56e-5641.55% (296) transmembrane transport protein MmpL5
M. leprae Br4923MLBr_02378-3e-5239.86% (276) hypothetical protein MLBr_02378
M. marinum MMMAR_0775-3e-5844.20% (276) MmpL family transport protein
M. avium 104MAV_1755-1e-5536.96% (303) MmpL4 protein
M. smegmatis MC2 155MSMEG_3584-2e-6545.86% (290) membrane protein, MmpL family protein
M. thermoresistible (build 8)TH_4046-5e-5538.41% (289) PUTATIVE Transport protein
M. ulcerans Agy99MUL_3688mmpL4_14e-5737.84% (296) transmembrane transport protein MmpL4_1
M. vanbaalenii PYR-1Mvan_3833-4e-5942.44% (271) transport protein

CLUSTAL 2.0.9 multiple sequence alignment


MLBr_02378|M.leprae_Br4923          -------MTVKCAN------------------DLDTHTKPPFVARMIHRF
MMAR_0775|M.marinum_M               -MSDDQAVSERAASNGASNGAGAENGNGNENGNGNGNGSRPSMARLIHRM
Mb0695c|M.bovis_AF2122/97           ------MIVQRTAAPTG-------------SVPPDRHAARPFIPRMIRTF
Rv0676c|M.tuberculosis_H37Rv        ------MIVQRTAAPTG-------------SVPPDRHAARPFIPRMIRTF
Mflv_2705|M.gilvum_PYR-GCK          ------------MSS---------------SRDRAALREPRSVARWIRRL
Mvan_3833|M.vanbaalenii_PYR-1       ------------MRA---------------HADR-DLRDPTPVARWIRRL
TH_4046|M.thermoresistible__bu      -------MTRPFGQP---------------TVTRKPLREPTAVARWIRRL
MAV_1755|M.avium_104                -MSDASNKTQPDLSAADTG--PINVKGLS----KAERGHRPYLPHAIRIF
MUL_3688|M.ulcerans_Agy99           -MSESN--SGASISTEDTG--PIEIGAATGGAPNRERGHRPVIPHTIRIL
MSMEG_3584|M.smegmatis_MC2_155      -------MPGQVGMS-------------------AHRAGRPFFARAVRVL
MAB_2571c|M.abscessus_ATCC_199      MHGDGSMTSGQQPPLPGDDADTGPVPVPTQRAMRHETHKHPAAARWLRVL
                                                                               .: :: :

MLBr_02378|M.leprae_Br4923          AVPIILVWLAIAVTVSVFIPSLEDVGQERSVSLSPKDAPSYIAMQKMGQV
MMAR_0775|M.marinum_M               AVPIVVFWVGLVAVLVMFVPSLEEVGKQHTVSLSPSDAESMIAMKRVGKV
Mb0695c|M.bovis_AF2122/97           AVPIILGWLVTIAVLNVTVPQLETVGQIQAVSMSPDAAPSMISMKHIGKV
Rv0676c|M.tuberculosis_H37Rv        AVPIILGWLVTIAVLNVTVPQLETVGQIQAVSMSPDAAPSMISMKHIGKV
Mflv_2705|M.gilvum_PYR-GCK          AVPIILGWLLLAVALNALVPQLEVVAAKNAVSMSPSNAPSMQAMADMGRL
Mvan_3833|M.vanbaalenii_PYR-1       AIPIILGWVLLVAALNLLVPQLEVVAAQNAVSMSPSDAPAMQAMSDMGRL
TH_4046|M.thermoresistible__bu      ALPIILGWLLVMVALNSVAPQLEVVAAQNAVSMSPSNAPSMQAMADMGRL
MAV_1755|M.avium_104                AVPIILGWLFVTVLVNVIVPTLEKVGEAHSAPMTPLDAPSMKAMMRLGHN
MUL_3688|M.ulcerans_Agy99           AVPIILGWVLLTVLVNVVVPSLEVVSEQHSAPMTPMDAPSMKAMMRLGHN
MSMEG_3584|M.smegmatis_MC2_155      ALPIVAFWILVTIGTNIFVPQAEKVADELAGPMIPTYAPSQVALLQMGEK
MAB_2571c|M.abscessus_ATCC_199      AIPVVLFWVIAAAVLNIFVPSLEETTAANAKAMIPRDAPSSAAAITQGQD
                                    *:*::  *:          *  * .    : .: *  * :  :    *. 

MLBr_02378|M.leprae_Br4923          FNEGNSDSVIMIVLEGD--KPLGDDAHRFYDGLIRKLRADK-HVQSVQDF
MMAR_0775|M.marinum_M               FNEFDTDSAVMIVLEGD--HPLGDEAHHYYDELVRKLKADKDHVQHVQDF
Mb0695c|M.bovis_AF2122/97           FEEGDSDSAAMIVLEGQ--RPLGDAAHAFYDQMIGRLQADTTHVQSLQDF
Rv0676c|M.tuberculosis_H37Rv        FEEGDSDSAAMIVLEGQ--RPLGDAAHAFYDQMIGRLQADTTHVQSLQDF
Mflv_2705|M.gilvum_PYR-GCK          FEESDSDSIALIVLESETDQPLGDDAHEYYDGLIAALLADTENVRNIQDT
Mvan_3833|M.vanbaalenii_PYR-1       FGESDSDSIAMVVLEGE--QPLGDDAHAYYDQLIEKLEAAPDHVRNIQDM
TH_4046|M.thermoresistible__bu      FEESDSDSMVMIVLKSD--HPLGDDAYAYYTDLVDRLEADTDHVRNVQDM
MAV_1755|M.avium_104                FHEFDSNSTVMIVLEGQ--QPLGPDAHKYYDNLIRQLRQDPKHIQHIQDF
MUL_3688|M.ulcerans_Agy99           FREFDSNSTVMIVLEGQ--HKLGDDAHQYYDSLIRQLRQDPEHIQHIQDF
MSMEG_3584|M.smegmatis_MC2_155      FGESDSTNLTMLVLEAD--RPLDDADHRFYDDLVRRLQSDPAHVQYVMDL
MAB_2571c|M.abscessus_ATCC_199      FQESAYTSAAVIVLETQG-RTLGEQDRQYYNKLVRGLLDDKEHVQSLMDL
                                    * *    .  ::**: :  : *.     :*  ::  *     ::: : * 

MLBr_02378|M.leprae_Br4923          WGDPLTAPGAQSNDGKAAYVQLSLAGNQGELLAQESIDAVRKIVVQT--P
MMAR_0775|M.marinum_M               WGDPLTAAGSQSPDGKAAYVQAYLVGNQGEAKANESVDAVRELVNDT--P
Mb0695c|M.bovis_AF2122/97           WGDPLTATGAQSSDGKAAYVQVKLAGNQGESLANESVEAVKTIVERL--A
Rv0676c|M.tuberculosis_H37Rv        WGDPLTATGAQSSDGKAAYVQVKLAGNQGESLANESVEAVKTIVERL--A
Mflv_2705|M.gilvum_PYR-GCK          WGDPLTEAAAQSSDGRAAYATLNLAGNMGETESNEAVAAVRDIVANS--P
Mvan_3833|M.vanbaalenii_PYR-1       WGDPLTEAAAQSTDGHAAYVALNLAGNMGETKSNESVAAVRDIVADS--P
TH_4046|M.thermoresistible__bu      WGDPLTEASAESSDGRAVYVQLNLAGNMGETKSNESVAAVRAIVDAS--S
MAV_1755|M.avium_104                WGDRLTAAGAQSADAKGAYVQVNLAGNQGTTLANESVDAVRKVIDEN--K
MUL_3688|M.ulcerans_Agy99           WGDRLTAAGAQSADGKSAYVMVNLAGNQGTTLANESVEAVRDVINRT--H
MSMEG_3584|M.smegmatis_MC2_155      WGEPITAAAVQSVDGKAAFVMLRLAGNTGKLEANESVDAVRDIVAAD--A
MAB_2571c|M.abscessus_ATCC_199      WGDPVTRSGQQSADARAATLTVRPTGDLADADSNRSIKAIRGTVEKLDKE
                                    **: :* .. :* *.:..      .*: .   ::.:: *::  :      

MLBr_02378|M.leprae_Br4923          APPGITAWVTGASALIADMHHSGDKSMIRITATSVIVILVTLLLVYRSFI
MMAR_0775|M.marinum_M               APPGVKAYVTGPAALIADQSTAGDASIQRVTFITIGVIFVMLLSVYRSLI
Mb0695c|M.bovis_AF2122/97           PPPGVKVYVTGSAALVADQQQAGDRSLQVIEAVTFTVIIVMLLLVYRSII
Rv0676c|M.tuberculosis_H37Rv        PPPGVKVYVTGSAALVADQQQAGDRSLQVIEAVTFTVIIVMLLLVYRSII
Mflv_2705|M.gilvum_PYR-GCK          PPPGVTVHVTGPAALIADVNIAGERSMALVLLVTFVVIIVLLLFFYRSIS
Mvan_3833|M.vanbaalenii_PYR-1       PPPGVQVHVTGPAALTADVNIAGESSMALILLVTFVVIIVLLLFFYRSIT
TH_4046|M.thermoresistible__bu      PPPGVEVHVTGPAALTADMNIAGERSMAIILLVTFTVITVVLLFFYRSIP
MAV_1755|M.avium_104                APPGVKAYVTGPAALSDDMHIIGNASLAKITLFTLGAIAIMLLLVYRSIV
MUL_3688|M.ulcerans_Agy99           EPAGVKAYVTGPAALSDDMHLIGNASLATITMFTLGAIAVMLLLVYRSIV
MSMEG_3584|M.smegmatis_MC2_155      PPPGLKVYVSGPAPLASDTLTIATASLKNITILTIILIVAMLLLVYRSVP
MAB_2571c|M.abscessus_ATCC_199      KPDGLRVYVSGPAPLASDTLTAADESMLMLTIVTIVVIIIMLLIAYRSFT
                                     * *: . *:*.:.*  *    .  *:  :   :.  *   **  ***. 

MLBr_02378|M.leprae_Br4923          TVILLLFTVGIESAVARGVVALLGHTGLIGLSTFAVNLLTSLAIAAGTDY
MMAR_0775|M.marinum_M               TVISVLVMVGIELMAARGVVAFLADNNVIGLSTFAVNLLVLMAIAAGTDY
Mb0695c|M.bovis_AF2122/97           TSAIMLTMVVLGLLATRGGVAFLGFHRIIGLSTFATNLLVVLAIAAATDY
Rv0676c|M.tuberculosis_H37Rv        TSAIMLTMVVLGLLATRGGVAFLGFHRIIGLSTFATNLLVVLAIAAATDY
Mflv_2705|M.gilvum_PYR-GCK          TVLLLLVVVGIQLLVARGVVAALAHVGVIGLSTYATNLLISLAVAAGTDY
Mvan_3833|M.vanbaalenii_PYR-1       TVVLLLIMVGVQMSVARGVVAALGHFQVIGLSTFAVNLLISLAVAAGTDY
TH_4046|M.thermoresistible__bu      TVVLLIAMVIVQLSIARGIVAALGHFQIIGLSTFAVNLLVALAVAAGTDY
MAV_1755|M.avium_104                TTLVQLFMTFVALACSRGVVAVLAYHNAFGLTTFAANILTMLAIAAGTDY
MUL_3688|M.ulcerans_Agy99           TTVIQLFMTGIALASSRGVVAVLGYHNVFGLTTFAANILTMLAIAAGTDY
MSMEG_3584|M.smegmatis_MC2_155      SLLVPLPAVLIELLAAKGVVAVLGHLGVIPLSSFAVNLLVALTLGAGTDY
MAB_2571c|M.abscessus_ATCC_199      RAIIPLVGVLITLATARGVVSLLVENHIIGISSFAMNMAVSLVLGVATDY
                                         :  . :    ::* *: *     : ::::* *:   :.:...***

MLBr_02378|M.leprae_Br4923          GIFITGRYQEARQANENKEAAFYTMYRGTFHVILGSGLTISGATFCLSFA
MMAR_0775|M.marinum_M               AIFVLGRYQEARGEGESREKAFYTMFHGTAHVVLGSGLTIAGAMYCLSFT
Mb0695c|M.bovis_AF2122/97           AIFLIGRYQEARGLGQDRESAYYTMFGGTAHVVLGSGLTIAGATFCLSFT
Rv0676c|M.tuberculosis_H37Rv        AIFLIGRYQEARGLGQDRESAYYTMFGGTAHVVLGSGLTIAGATFCLSFT
Mflv_2705|M.gilvum_PYR-GCK          AIFLVGRYQEARASGADHEEAYYEMFHGTAHVVLGSGLTIAGAMLCLSFT
Mvan_3833|M.vanbaalenii_PYR-1       AIFLVGRYQEARASGADPEAAYYEMFGGTAHVVLGSGLTIAGAMYCLSFA
TH_4046|M.thermoresistible__bu      AIFMVGRYQEARVAGADPESAYYEMFRGTAHVVLGSGLTIAGAMLCLSFT
MAV_1755|M.avium_104                GIFLIGRYQEALAAGEDRESAYYTTFKGVAPVVLGSGLTIAGATYCLSFS
MUL_3688|M.ulcerans_Agy99           GIFLVGRYQEARQAGEDRQDAYYTTFRGVAPVVLGSGLTIAGATYCLSFA
MSMEG_3584|M.smegmatis_MC2_155      GIFMLGRYQEARRAGESREEAYFTAYRSVAPIIIGSGLTIAGACFCLSLA
MAB_2571c|M.abscessus_ATCC_199      GIFYLGRFQEALRSGR-------TVSRRTTPRCAAS--------------
                                    .**  **:***   .             .     .*              

MLBr_02378|M.leprae_Br4923          RMPYFQTLGVPCAVGMLIAVAVALTLGPAVLTVGSRFG-LFEPKRLIKVR
MMAR_0775|M.marinum_M               RLPYFQTLGAPCAVGMLVAVLAALTLGPAVLVVGSFFK-LFDPKRKMRTR
Mb0695c|M.bovis_AF2122/97           RLPYFQTLGVPLAIGMVIVVAAALTLGPAIIAVTSRFGKLLEPKRMARVR
Rv0676c|M.tuberculosis_H37Rv        RLPYFQTLGVPLAIGMVIVVAAALTLGPAIIAVTSRFGKLLEPKRMARVR
Mflv_2705|M.gilvum_PYR-GCK          RMPYFQSMGIPCAVGIAAGVAVALTLGPAIVTVGSRFN-LLEPKRAMRIR
Mvan_3833|M.vanbaalenii_PYR-1       RMPYFQSMGVPCAVGILAGVAVALTLGPAIVTVGSRFG-LLEPKRAMRIR
TH_4046|M.thermoresistible__bu      RMPYFQSMGVPCAVGVAAGVAVALTMGPAVVAVASRFG-LLEPRRAMRIR
MAV_1755|M.avium_104                RLPWFNTMGAPVAIGMLVVVLAGVTLGPAVVFVGSRFHFFE--RQAKRGR
MUL_3688|M.ulcerans_Agy99           RLPWFNTMGAPVAIGMLVVVLAGLTLGPAVVFVGSRFHPFESKRAANRGR
MSMEG_3584|M.smegmatis_MC2_155      RLDYFHTMGPAVAVSMLCTIAAALTLAPALLTLGSRRG-LFDPRRLNSGR
MAB_2571c|M.abscessus_ATCC_199      -------------------------------------------RTSSSDR
                                                                               :     *

MLBr_02378|M.leprae_Br4923          GWRRIGTVVVRWPLPILITTCAIAMVGLLALPGYRTNYKDRAYLPASIPA
MMAR_0775|M.marinum_M               GWRRVGTAIVRWPGPILAVSIAIALIGLLALPGYRTNYDSKKYLPASTPT
Mb0695c|M.bovis_AF2122/97           GWRKVGAAIVRWPGPILVGAVALALVGLLTLPGYRTNYNDRNYLPADLPA
Rv0676c|M.tuberculosis_H37Rv        GWRKVGAAIVRWPGPILVGAVALALVGLLTLPGYRTNYNDRNYLPADLPA
Mflv_2705|M.gilvum_PYR-GCK          AWRRIGTMVVRWPGPILVASLALALVGLAALPGYQTSYDDTRYVPESIPA
Mvan_3833|M.vanbaalenii_PYR-1       AWRRVGATVVRWPGPILVASLALALIGLAALPGYKTSYDDTRYIPESIPA
TH_4046|M.thermoresistible__bu      TWRRIGTMVVRWPGPIMVASLTLALIGLAALPGYQTSYDDTRYVPGDIPA
MAV_1755|M.avium_104                LWRRVGTAVVRWPAPVLAVSAAVVLVGMIALPSFHTSYNDRHYLPLSAPS
MUL_3688|M.ulcerans_Agy99           LWRRVGTAVVRWPAPILALSGAIVLVGMVALPGFKTSYNDRYYLPASAPS
MSMEG_3584|M.smegmatis_MC2_155      LYRHIATSVVRWPKPVFVASAVVVLVGAVFVPTYQVGYDDRAYQPADAPA
MAB_2571c|M.abscessus_ATCC_199      VWRSRVRACA----------------------------------------
                                     :*      .                                        

MLBr_02378|M.leprae_Br4923          NQGFAAADRHFPQARMKPEILMIESDHDMRNPADFLILDKLARGIFRVPG
MMAR_0775|M.marinum_M               NVGYTAADRHFSQARMNPELLMVETDHDMRNPADMLVIDRIAKGVFHLPG
Mb0695c|M.bovis_AF2122/97           NEGYAAAERHFSQARMNPEVLMVESDHDMRNSADFLVINKIAKAIFAVEG
Rv0676c|M.tuberculosis_H37Rv        NEGYAAAERHFSQARMNPEVLMVESDHDMRNSADFLVINKIAKAIFAVEG
Mflv_2705|M.gilvum_PYR-GCK          NAGLQAATQHFTLSRMSPEILIVEADRDLRNPADFLVLDRLAKRVFAVEG
Mvan_3833|M.vanbaalenii_PYR-1       NAGLQAATKYFSLSRMSPEVLIVEADRDLRNSSDFLILDRLAKRVFNVEG
TH_4046|M.thermoresistible__bu      NVGLRAATEHFSMSRMSPEVLLVQTDRDLRNSADFLVLDRLAKRVFAVEG
MAV_1755|M.avium_104                NQGQEAANRHFSEARMNPDLLMIESDHDMRNPADMLVLDRVAKNEMRTLG
MUL_3688|M.ulcerans_Agy99           NLGEAAADRHFSHARMNPDMLMVEAEHDMRNPADMLVLDKVAKNVIRTVG
MSMEG_3584|M.smegmatis_MC2_155      KLGFEAADRHFPQSKLMSELLMVESDHDMRNSADFISLDRAAKSLIRLPG
MAB_2571c|M.abscessus_ATCC_199      --------------------------------------------------
                                                                                      

MLBr_02378|M.leprae_Br4923          ISRVQAITRPDGTAMDHTSIPFQISMQNAGQVQTMKYQKDRMNDLLRQAE
MMAR_0775|M.marinum_M               VARVQAVTRPLGKPIEHSSIPFQISMQNTVQVENMQYMKQRMADMLIQAA
Mb0695c|M.bovis_AF2122/97           ISRVQAITRPDGKPIEHTSIPFLISMQGTSQKLTEKYNQDLTARMLEQVN
Rv0676c|M.tuberculosis_H37Rv        ISRVQAITRPDGKPIEHTSIPFLISMQGTSQKLTEKYNQDLTARMLEQVN
Mflv_2705|M.gilvum_PYR-GCK          VARVQAPSRPDGSPIAKTSIPFLISMQGVGQQQNMKLMQDRMDDMRTQAD
Mvan_3833|M.vanbaalenii_PYR-1       VARVQAPSRPDGAPIAHTSIPFLISMQGVGQQQNMKLMKDRIADMRVQAD
TH_4046|M.thermoresistible__bu      VARVQSVTRPDGMPIAHTSIPFLISMQGVGQQQNMKLMKDRITDMRTQAE
MAV_1755|M.avium_104                IAMVQDITRPLGIPIQHSSIPFQNSVQSQTTMQNMGFLKERMNDILKMAD
MUL_3688|M.ulcerans_Agy99           IAMIQDITRPLGIPIQHSSIPFQNSMQSQTMMQNMAFLKERMADMTKMAD
MSMEG_3584|M.smegmatis_MC2_155      VAMVQSITRPLGRPLEHATIPYLFTMQGSTSGQQLPFDQQLNENTDRQAD
MAB_2571c|M.abscessus_ATCC_199      --------------------------------------------------
                                                                                      

MLBr_02378|M.leprae_Br4923          NMAETIASMRRMHQLMALLTENTHHILNDTVEMQKTTSKLRDEIANFDDF
MMAR_0775|M.marinum_M               AMQDSIDTLDRMYDIMGKMVETTHDMDGLTHDMVEITDELRDHIADFDDF
Mb0695c|M.bovis_AF2122/97           DIQSNIDQMERMHSLTQQMADVTHEMVIQMTGMVVDVEELRNHIADFDDF
Rv0676c|M.tuberculosis_H37Rv        DIQSNIDQMERMHSLTQQMADVTHEMVIQMTGMVVDVEELRNHIADFDDF
Mflv_2705|M.gilvum_PYR-GCK          NLGKTLGTMRTMYGLMTRLSEVTTVMIDDFTEMQQTVHQIRDMVANFDDQ
Mvan_3833|M.vanbaalenii_PYR-1       DIGETIATMKTMYGLMTKFSNITTVMIDDMTEMRDTVHQIRDMVATFDDQ
TH_4046|M.thermoresistible__bu      ELAETVQTMKRLYRLMTQFTGVSTDMIADMKGMQETVHQLRDAMADFDDF
MAV_1755|M.avium_104                DLQTQIDTTQRQYEVSMDLANAADDSAKTTAVTSQITDSLRDHIADFDDT
MUL_3688|M.ulcerans_Agy99           EMQVLIDTTERMYAVMRELDTTTTDMARVTAETSTITDELRDHLAEFDDF
MSMEG_3584|M.smegmatis_MC2_155      IQAHSLQVIQQVISITTQMSDELHATTVTFENLKEVTDEVNEGISDLDDF
MAB_2571c|M.abscessus_ATCC_199      --------------------------------------------------
                                                                                      

MLBr_02378|M.leprae_Br4923          WRPIRSYFYWERHCFNIPICWSFRSIFDALDGVDQIDERLNSIVGDIKNM
MMAR_0775|M.marinum_M               WRPIRSYFYWEKHCYDVPICWSLRSIFDALDGVDKITEKLAALSRDMDRL
Mb0695c|M.bovis_AF2122/97           FRPIRSYFYWEKHCYDIPVCWSLRSVFDTLDGIDVMTEDINNLLPLMQRL
Rv0676c|M.tuberculosis_H37Rv        FRPIRSYFYWEKHCYDIPVCWSLRSVFDTLDGIDVMTEDINNLLPLMQRL
Mflv_2705|M.gilvum_PYR-GCK          FRPVRNYFYWEPHCYNIPLCWSFRSLFDSMDGISTMTESFDKALVNMETM
Mvan_3833|M.vanbaalenii_PYR-1       FRPIRNYFYWEPHCYNIPLCWSFRSLFDSMDGISVMTDTFDKAVANMDEM
TH_4046|M.thermoresistible__bu      FRPIRNXX------------------------------------------
MAV_1755|M.avium_104                FRPIRTYFYWEKHCYDIPVCIGLRSLFDTFDGFDQLAEQFHYLTTDIAHT
MUL_3688|M.ulcerans_Agy99           WRPMRSYFYWEKHCFDVPICWSFRSLFDSLDGIDKLSEKFSELTEDIQRT
MSMEG_3584|M.smegmatis_MC2_155      LRPLKNYFYWEPHCFDIPVCFAIRSLFDSLDGIDRLDEQIGNAVESFEAI
MAB_2571c|M.abscessus_ATCC_199      --------------------------------------------------
                                                                                      

MLBr_02378|M.leprae_Br4923          DLLMPQMLEQFPPMIESMESMRTIMLTMHSTMSGIFDQMNELSDNANTMG
MMAR_0775|M.marinum_M               DILMPQMRAQIPFQIASMKTMKTMMLTMHSSMSSLYDQMDEMSKNSTAMG
Mb0695c|M.bovis_AF2122/97           DTLMPQLTAMMPEMIQTMKSMKAQMLSMHSTQEGLQDQMAAMQEDSAAMG
Rv0676c|M.tuberculosis_H37Rv        DTLMPQLTAMMPEMIQTMKSMKAQMLSMHSTQEGLQDQMAAMQEDSAAMG
Mflv_2705|M.gilvum_PYR-GCK          RSLLPQMLATFPPMIETMESMRQMMLTTYATMGGFYDQMDELTQDSTEMG
Mvan_3833|M.vanbaalenii_PYR-1       KALLPQMLATFPPMIETMESMRQMMLTTYATMGGFYDQMDELTRDSTEMG
TH_4046|M.thermoresistible__bu      --------------------------------------------------
MAV_1755|M.avium_104                AKASRDLTALFPTLITTLKTTRGITLTLYQTFKAMIDQMEAMSNTAVVMG
MUL_3688|M.ulcerans_Agy99           AGLTSQMLTLIPPMIATMKTTKALTLTMQSTFSAMLDQMDELSNTAIVMG
MSMEG_3584|M.smegmatis_MC2_155      DRLLPQMITQLEQMKIAGKATLSLLQNNYGSAHLQSTQTDQTYDDLINVG
MAB_2571c|M.abscessus_ATCC_199      --------------------------------------------------
                                                                                      

MLBr_02378|M.leprae_Br4923          KAFDTAKNDDSFYLPPEVFKNTDFKRAMKSFLSSDGHAARFIILHRGDPA
MMAR_0775|M.marinum_M               KAFDAARNDDSFYIPPEVFDNADFKRGLKMFLSPDGHAVRFIISHEGDPA
Mb0695c|M.bovis_AF2122/97           EAFDASRNDDSFYLPPEVFDNPDFQRGLEQFLSPDGHAVRFIISHEGDPM
Rv0676c|M.tuberculosis_H37Rv        EAFDASRNDDSFYLPPEVFDNPDFQRGLEQFLSPDGHAVRFIISHEGDPM
Mflv_2705|M.gilvum_PYR-GCK          KAFDEAKNDDSFYLPPEVFENEDFKRAMESFFSPDGKTVRMLVSHRGDPT
Mvan_3833|M.vanbaalenii_PYR-1       KAFDAAKNDDSFYLPPEVFENEDFKRAMESFFSPDGKTVRMLIAHRGNPT
TH_4046|M.thermoresistible__bu      -------------------------XCCRAACTPPG--------------
MAV_1755|M.avium_104                QSFDASKNDDFFYLPPEAFDNPDFQTGLRMFLSPDGKSARFFITHQGDPM
MUL_3688|M.ulcerans_Agy99           QSFDASKNDDFFYLPPEAFDNPDFQTGLRMFLSPDGKSARFFITHQGDPM
MSMEG_3584|M.smegmatis_MC2_155      NDFDAARSDDFFYIPHEAFDNDDVKTGMKLLMSPDGKAARFIITHEGNAM
MAB_2571c|M.abscessus_ATCC_199      --------------------------------------------------
                                                                                      

MLBr_02378|M.leprae_Br4923          SVAGIASINAIRTAAEEALKGTPLEDTKIYLAGTAAVFKDIDEGANWDLV
MMAR_0775|M.marinum_M               STEGISHVKPIMDEAKQAIKGTPLEGAKIYLAGTASVYKDMRDGSRWDLL
Mb0695c|M.bovis_AF2122/97           SQAGIARIAKIKTAAKEAIKGTPLEGSAIYLGGTAAMFKDLSDGNTYDLM
Rv0676c|M.tuberculosis_H37Rv        SQAGIARIAKIKTAAKEAIKGTPLEGSAIYLGGTAAMFKDLSDGNTYDLM
Mflv_2705|M.gilvum_PYR-GCK          TPEALARVEPIKIAAIEALKGTPLENAQIQLGGTAATFKDMSDGSRYDMM
Mvan_3833|M.vanbaalenii_PYR-1       TDEALQRVEPIKIAAIEALKGTPLENAQIQLGGTAATFKDMSDGSRYDLL
TH_4046|M.thermoresistible__bu      -------------------RGTAAPSGRVCPG---TPCTDSCGGNSMHG-
MAV_1755|M.avium_104                SPEGIKRVDAERTAAQEGLKQSSLSDARVYLGGTAATFKDMADGEKYDLM
MUL_3688|M.ulcerans_Agy99           TPEGISRVDAERTAAQEGLKQSSLSDAKVYLGGTAATFKDMADGEKYDLM
MSMEG_3584|M.smegmatis_MC2_155      AQEGIEHVEQIPDAIKMALKETSLAGAKVYLGGAASSTKDIQDYAASDLL
MAB_2571c|M.abscessus_ATCC_199      --------------------------------------------------
                                                                                      

MLBr_02378|M.leprae_Br4923          IAGISSLCLIFIIMLIITRAFVAAAVIVGTVALSLGASFGLSVLLWQHIL
MMAR_0775|M.marinum_M               IAGVAAVSLILIIMLIITRSLVAAVVIVGTVLLSLGASFGLSVLVWQDIF
Mb0695c|M.bovis_AF2122/97           IAGISALCLIFIIMLIITRSVVAAAVIVGTVVLSLGASFGLSVLIWQHIL
Rv0676c|M.tuberculosis_H37Rv        IAGISALCLIFIIMLITTRSVVAAAVIVGTVVLSLGASFGLSVLIWQHIL
Mflv_2705|M.gilvum_PYR-GCK          IAILSALCLVLVIMLVLTRSLVAAVVIVGTVALSLGASFGVSVLIWQHLL
Mvan_3833|M.vanbaalenii_PYR-1       IAVISALCLVLMIMLVLTRSLVAALVIVGTVTLSLGASFGISILIWQHIV
TH_4046|M.thermoresistible__bu      --------------------------------------------------
MAV_1755|M.avium_104                IAVVSALTLIFMIMLLLTRSVVAALVIVGTAASSIAASFGLSVLIWQDLF
MUL_3688|M.ulcerans_Agy99           IAVVSALTLIFLIMLLLTRSVVAALVIVGTAASSIAASFGLSVLIWQDLF
MSMEG_3584|M.smegmatis_MC2_155      IVAIAAFVLIFLIMLYLTRSLVAAMVIPGTVAFSFAGAFGLSVLVWQHLI
MAB_2571c|M.abscessus_ATCC_199      --------------------------------------------------
                                                                                      

MLBr_02378|M.leprae_Br4923          GIELHYLVLAMSVIVLLAVGSDYNLLLVSRFKQEIQAGLKTGIIRSMGGT
MMAR_0775|M.marinum_M               GVELHWMVLAMSVILLLAVGSDYNLLLVSRLKEEIGAGLKTGIIRAMAGT
Mb0695c|M.bovis_AF2122/97           GIELHWLVLAMAVIILLAVGADYNLLLVARLKEEIHAGINTGIIRAMGGS
Rv0676c|M.tuberculosis_H37Rv        GIELHWLVLAMAVIILLAVGADYNLLLVARLKEEIHAGINTGIIRAMGGS
Mflv_2705|M.gilvum_PYR-GCK          GVELHWMVLVMSIIALIAVGSDYNLLLVSRFKEEIGAGIKTGIIRAIGGT
Mvan_3833|M.vanbaalenii_PYR-1       GIELHWMVLALSIIALIAVGSDYNLLLVSRFKEEIPAGIKTGIIRAIGGT
TH_4046|M.thermoresistible__bu      --------------------------------------------------
MAV_1755|M.avium_104                GIRIHWIVAALSVIILLAVGSDYNLLLVSRFREEIHGGLKTGIIRSMAGT
MUL_3688|M.ulcerans_Agy99           GIKIHWIVAALSVIILLAVGSDYNLLLVSRFREEIHAGLKTGIIRSMAGT
MSMEG_3584|M.smegmatis_MC2_155      GLPLHWLVLPLAFIILVAVGSDYNLLLISRVKEESGAGLNTALIRALGST
MAB_2571c|M.abscessus_ATCC_199      --------------------------------------------------
                                                                                      

MLBr_02378|M.leprae_Br4923          GKVVTNAGLVFAFTMASMVVSDLRVIGQVGTTIGLGLLFDTLIVRSFMMP
MMAR_0775|M.marinum_M               GGVVTTAGLVFAATMASFIFSDLRVIGQVGTTIGLGLLFDTLIVRSFMTP
Mb0695c|M.bovis_AF2122/97           GSVVTAAGLVFAFTMMSFAVSELTVMAQVGTTIGMGLLFDTLIVRSFMTP
Rv0676c|M.tuberculosis_H37Rv        GSVVTAAGLVFAFTMMSFAVSELTVMAQVGTTIGMGLLFDTLIVRSFMTP
Mflv_2705|M.gilvum_PYR-GCK          GSVVSVAGVVFALTMASMVVSDLKVIAQVGTTIGLGLLFDTFIVRAFMMP
Mvan_3833|M.vanbaalenii_PYR-1       GSVVTVAGVVFALTMASMVVSDLRVMAQVGTTIGLGLLFDTFIVRAFMMP
TH_4046|M.thermoresistible__bu      --------------------------------------------------
MAV_1755|M.avium_104                GGVVTAAGLVFAFTMAAMLGSELRVLGQFGSTVCIGLLLDTLIVRTLLMP
MUL_3688|M.ulcerans_Agy99           GGVVTAAGLVFAFTMASMLGSDLRVLGQFGSTVCIGLLLDTLIVRTLLMP
MSMEG_3584|M.smegmatis_MC2_155      GAVVTSAGLVFAFTMLSMLASNLAAVGQLGSTVCIGLLLDTMIVRSLVVP
MAB_2571c|M.abscessus_ATCC_199      --------------------------------------------------
                                                                                      

MLBr_02378|M.leprae_Br4923          SIAALLGRWFWWPQQGRTRPLLTVAAPVG---------LP----------
MMAR_0775|M.marinum_M               SIAALMGRWFWWPQQVRTRPASQLLRPYGPRPLVRALLLPRNGDSADGPE
Mb0695c|M.bovis_AF2122/97           SIAALLGKWFWWPQVVRQRPVPQPWPSPA---------------------
Rv0676c|M.tuberculosis_H37Rv        SIAALLGKWFWWPQVVRQRPIPQPWPSPA---------------------
Mflv_2705|M.gilvum_PYR-GCK          SIATLLGRWFWWPLVVRSRPLRPRPQQQALG-------------------
Mvan_3833|M.vanbaalenii_PYR-1       AIATLLGRWFWWPLVVRSRPLRLPPRT-----------------------
TH_4046|M.thermoresistible__bu      --------------------------------------------------
MAV_1755|M.avium_104                SIATLLGRWFWWPMVVHPRGDNARRPVPASS-------------------
MUL_3688|M.ulcerans_Agy99           SIATLLGRWFWWPQVVHPRGDNARPRVAAPTH------------------
MSMEG_3584|M.smegmatis_MC2_155      CLLRLLGPWFWWPTFIRQRPLRTPDRFARPG-------------------
MAB_2571c|M.abscessus_ATCC_199      --------------------------------------------------
                                                                                      

MLBr_02378|M.leprae_Br4923          ---PDRSLVYSD--
MMAR_0775|M.marinum_M               DTNTERLAVSSPHY
Mb0695c|M.bovis_AF2122/97           ---SARTFALV---
Rv0676c|M.tuberculosis_H37Rv        ---SARTFALV---
Mflv_2705|M.gilvum_PYR-GCK          ---VGGQQG-----
Mvan_3833|M.vanbaalenii_PYR-1       --------------
TH_4046|M.thermoresistible__bu      --------------
MAV_1755|M.avium_104                --------------
MUL_3688|M.ulcerans_Agy99           --------------
MSMEG_3584|M.smegmatis_MC2_155      ---PSRRIMTDR--
MAB_2571c|M.abscessus_ATCC_199      --------------