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M. tuberculosis H37Rv Rv0676c (mmpL5)

annotation: PROBABLE CONSERVED TRANSMEMBRANE TRANSPORT PROTEIN MMPL5
coordinates: 775586 - 778480
length: 964

IVQRTAAPTGSVPPDRHAARPFIPRMIRTFAVPIILGWLVTIAVLNVTVPQLETVGQIQAVSMSPDAAPS
MISMKHIGKVFEEGDSDSAAMIVLEGQRPLGDAAHAFYDQMIGRLQADTTHVQSLQDFWGDPLTATGAQS
SDGKAAYVQVKLAGNQGESLANESVEAVKTIVERLAPPPGVKVYVTGSAALVADQQQAGDRSLQVIEAVT
FTVIIVMLLLVYRSIITSAIMLTMVVLGLLATRGGVAFLGFHRIIGLSTFATNLLVVLAIAAATDYAIFL
IGRYQEARGLGQDRESAYYTMFGGTAHVVLGSGLTIAGATFCLSFTRLPYFQTLGVPLAIGMVIVVAAAL
TLGPAIIAVTSRFGKLLEPKRMARVRGWRKVGAAIVRWPGPILVGAVALALVGLLTLPGYRTNYNDRNYL
PADLPANEGYAAAERHFSQARMNPEVLMVESDHDMRNSADFLVINKIAKAIFAVEGISRVQAITRPDGKP
IEHTSIPFLISMQGTSQKLTEKYNQDLTARMLEQVNDIQSNIDQMERMHSLTQQMADVTHEMVIQMTGMV
VDVEELRNHIADFDDFFRPIRSYFYWEKHCYDIPVCWSLRSVFDTLDGIDVMTEDINNLLPLMQRLDTLM
PQLTAMMPEMIQTMKSMKAQMLSMHSTQEGLQDQMAAMQEDSAAMGEAFDASRNDDSFYLPPEVFDNPDF
QRGLEQFLSPDGHAVRFIISHEGDPMSQAGIARIAKIKTAAKEAIKGTPLEGSAIYLGGTAAMFKDLSDG
NTYDLMIAGISALCLIFIIMLITTRSVVAAAVIVGTVVLSLGASFGLSVLIWQHILGIELHWLVLAMAVI
ILLAVGADYNLLLVARLKEEIHAGINTGIIRAMGGSGSVVTAAGLVFAFTMMSFAVSELTVMAQVGTTIG
MGLLFDTLIVRSFMTPSIAALLGKWFWWPQVVRQRPIPQPWPSPASARTFALV*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv0676cmmpL5-100% (964)PROBABLE CONSERVED TRANSMEMBRANE TRANSPORT PROTEIN MMPL5
M. tuberculosis H37RvRv0450cmmpL40.065.41% (931) transmembrane transport protein MmpL4
M. tuberculosis H37RvRv2339mmpL90.061.45% (926) transmembrane transport protein MmpL9

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0695cmmpL50.099.79% (964) transmembrane transport protein MmpL5
M. gilvum PYR-GCKMflv_3435-0.075.90% (946) transport protein
M. leprae Br4923MLBr_02378-0.062.81% (933) hypothetical protein MLBr_02378
M. abscessus ATCC 19977MAB_4382c-0.065.23% (949) putative membrane protein, MmpL
M. marinum MMMAR_1005mmpL50.092.26% (956) transmembrane transport protein, MmpL5
M. avium 104MAV_2510-0.072.68% (948) MmpL4 protein
M. smegmatis MC2 155MSMEG_0225-0.071.05% (950) MmpL4 protein
M. thermoresistible (build 8)TH_3260-0.070.09% (936) PUTATIVE MmpL4 protein
M. ulcerans Agy99MUL_0757mmpL50.092.05% (956) transmembrane transport protein, MmpL5
M. vanbaalenii PYR-1Mvan_3189-0.075.55% (953) transport protein

CLUSTAL 2.0.9 multiple sequence alignment


Rv0676c|M.tuberculosis_H37Rv        -MIVQRTAAPTGSVPPDRH-----AARP-FIPRMIRTFAVPIILGWLVTI
Mb0695c|M.bovis_AF2122/97           -MIVQRTAAPTGSVPPDRH-----AARP-FIPRMIRTFAVPIILGWLVTI
MMAR_1005|M.marinum_M               -MTATTTDTPTDVVPPAEH-----PPRP-FIPRMIRTFAVPLILGWVLLI
MUL_0757|M.ulcerans_Agy99           -MTATTTDTPTDVVPPAEH-----PPRP-FIPRMIRTFAVPLILGWVLLI
Mflv_3435|M.gilvum_PYR-GCK          -MSAPVSDARTDEFPAAHG-----PHRS-FIPRMIRLFAVPIILGWIALI
Mvan_3189|M.vanbaalenii_PYR-1       -MSAPVSDARTDEFPAARQ-----PHRP-FIPRMIRLFAVPIILGWIALI
MSMEG_0225|M.smegmatis_MC2_155      --MSTP-DAPTEAIPSAHG--KYTNHGG--IAKLIRTLAVPIILVWVALI
TH_3260|M.thermoresistible__bu      -MTANPGHVRTDEAPTDRLDIKVSTHGPSFISTWIRRLSLPIIVGWIALI
MAV_2510|M.avium_104                -MSTTFDDTRTDAIPVVKEP----VREK--IPRFIRAFAVPIIIGWIALI
MAB_4382c|M.abscessus_ATCC_199      -MSKPMNDPTTDAFPAARH-----AARP-WLPRMIRVLAVPIVLGWIAVT
MLBr_02378|M.leprae_Br4923          MTVKCANDLDTHTKP------------P-FVARMIHRFAVPIILVWLAIA
                                              *   *               :.  *: :::*::: *:   

Rv0676c|M.tuberculosis_H37Rv        AVLNVTVPQLETVGQIQAVSMSPDAAPSMISMKHIGKVFEEGDSDSAAMI
Mb0695c|M.bovis_AF2122/97           AVLNVTVPQLETVGQIQAVSMSPDAAPSMISMKHIGKVFEEGDSDSAAMI
MMAR_1005|M.marinum_M               AVLNSVVPQLEVVGQMQAVSMSPDAAPSMISMKHIGKVFREGDSDSAAMI
MUL_0757|M.ulcerans_Agy99           AVLNSVVPQLEVVGQMQAVSMSPDAAPSMISMKHIGKVFREGDSDSAAMI
Mflv_3435|M.gilvum_PYR-GCK          VVVNVTVPQLETVGEAQAVSMSPNDAPSMISMKKVGELFEEGDSDSSVMI
Mvan_3189|M.vanbaalenii_PYR-1       VILNVTVPQLEAVGEARAVSMSPNEAPSLISMKKVGELFREGDSDSSVMI
MSMEG_0225|M.smegmatis_MC2_155      AVLNTIVPQLEEVGEMRSVSMSPDDAPSMIAMKRVGEVFEEFKSNSSVMI
TH_3260|M.thermoresistible__bu      ALLNITVPQLEVVGEMRAVSMSPDEAPSMVAMKRVGELFDEGSSDSQVMI
MAV_2510|M.avium_104                AVLNVVVPQLDEVGKMRSVEMTPDDAQSVVATKRMGAVFNEYKSNSSVMI
MAB_4382c|M.abscessus_ATCC_199      IALNTVVPQLEEVGHMRAVSMSPNDAPAMIATKRVGEVFEEFKTSSSVMI
MLBr_02378|M.leprae_Br4923          VTVSVFIPSLEDVGQERSVSLSPKDAPSYIAMQKMGQVFNEGNSDSVIMI
                                      :.  :*.*: **. ::*.::*. * : :: :::* :* * .:.*  **

Rv0676c|M.tuberculosis_H37Rv        VLEGQRPLGDAAHAFYDQMIGRLQADTTHVQSLQDFWGDPLTATGAQSSD
Mb0695c|M.bovis_AF2122/97           VLEGQRPLGDAAHAFYDQMIGRLQADTTHVQSLQDFWGDPLTATGAQSSD
MMAR_1005|M.marinum_M               VLEGQEPLGAAAHKFYDKMITKLRADTKHVQSVQDFWGDPLTATGAQSGD
MUL_0757|M.ulcerans_Agy99           VLEGQEPLGAAAHKFYDKMITKLRADTKHVQSVQDFWGDPLTATGAQSGD
Mflv_3435|M.gilvum_PYR-GCK          VFEGDQPLGDEAHAWYDELVDRLEADTAHVQSVQDFWSDPLTASGSQSND
Mvan_3189|M.vanbaalenii_PYR-1       VFEGDQPLGDEAHAWYDELVERLRADTKHVQSVQDFWSDPLTASGSQSND
MSMEG_0225|M.smegmatis_MC2_155      VLEGEQPLGDEAHKYYDEIVDKLEADKTHIEHVQDFWGDPLTASGAQSSD
TH_3260|M.thermoresistible__bu      VLEGEEPLGADARAFYDELVKRLEADDAHVENVQDLWSDPLTATGVQSPD
MAV_2510|M.avium_104                VLEGQQPLGADAHAYYDEIVRRLNADTKHVEHVQDMWSDPLTGAGAQSND
MAB_4382c|M.abscessus_ATCC_199      VLEGEQSLGADAHRFYDQMVRDLRADTTHVQHVQDFWADALTAAAAQSSD
MLBr_02378|M.leprae_Br4923          VLEGDKPLGDDAHRFYDGLIRKLRAD-KHVQSVQDFWGDPLTAPGAQSND
                                    *:**:..**  *: :** ::  *.**  *:: :**:*.*.**... ** *

Rv0676c|M.tuberculosis_H37Rv        GKAAYVQVKLAGNQGESLANESVEAVKTIVERLA---PPPGVKVYVTGSA
Mb0695c|M.bovis_AF2122/97           GKAAYVQVKLAGNQGESLANESVEAVKTIVERLA---PPPGVKVYVTGSA
MMAR_1005|M.marinum_M               GKAAYVQVKLAGNQGESLANESVEAVKTIVDSLQ---APPGVKVYVTGSA
MUL_0757|M.ulcerans_Agy99           GKAAYVQVKLAGNQGESLANESVEAVKTIVDSLQ---APPGVKVYVTGSA
Mflv_3435|M.gilvum_PYR-GCK          GKAAYVQVKLSGNQGEALANESVKAVQQTVSSLE---PPPGVRAFVTGPA
Mvan_3189|M.vanbaalenii_PYR-1       GKAAYVQVKLAGNQGESLANESVQAAQEIVRSLE---PPPGVRAFVTGPA
MSMEG_0225|M.smegmatis_MC2_155      GLASYVQVYTAGNQGEALANESVKAVQDIVDSV---QAPPGVTAYVTGPA
TH_3260|M.thermoresistible__bu      GKSAYVQVKLAGNQGEALANESVETVREMIATVSEEMAPEGVQAFVTGGA
MAV_2510|M.avium_104                GKASYVQVYLAGNQGEALANESVESVQNIVKSVQ---APNGVKAYVTGPA
MAB_4382c|M.abscessus_ATCC_199      GKAAYVQVYIAGDQGEALANESVEAVRHITAAVP---PSPGVRVYVTGPA
MLBr_02378|M.leprae_Br4923          GKAAYVQLSLAGNQGELLAQESIDAVRKIVVQTP---APPGITAWVTGAS
                                    * ::***:  :*:*** **:**:.:.:          .. *: .:*** :

Rv0676c|M.tuberculosis_H37Rv        ALVADQQQAGDRSLQVIEAVTFTVIIVMLLLVYRSIITSAIMLTMVVLGL
Mb0695c|M.bovis_AF2122/97           ALVADQQQAGDRSLQVIEAVTFTVIIVMLLLVYRSIITSAIMLTMVVLGL
MMAR_1005|M.marinum_M               ALVADQQLAGDRSLQLIEMVTFTVIIVMLLLVYRSIITAAIMLTMVVLGL
MUL_0757|M.ulcerans_Agy99           ALVADQQLAGDRSLQLIEMVTFTVIIVMLLLVYRSIITAAIMLTMVVLGL
Mflv_3435|M.gilvum_PYR-GCK          ALAADQHIAGDRSMRLIEAATFTVIIVMLLLVYRSIVTVLITLVMVVMSL
Mvan_3189|M.vanbaalenii_PYR-1       ALAADQHIASDRSVRVIELVTFAVIIVMLLLVYRSIVTVLLTLVMVVLSL
MSMEG_0225|M.smegmatis_MC2_155      AMSADQQIAGDRSMRMIEALTFTVIIIMLLMVYRSIITVILSLVMVVFSL
TH_3260|M.thermoresistible__bu      AMSADQQEAGDSSLRVIEALTFLVITTMLLFVYRSVITVLIALFMVLIGL
MAV_2510|M.avium_104                ALSADQHTAGDRSLQLITAATFTVIIGMLLLVYRSVITVLLTLVMVVLEL
MAB_4382c|M.abscessus_ATCC_199      TTSADQEIVANDSMELIELVTFGVIMVMLLLVYRSVITMVIVVAMVMLEL
MLBr_02378|M.leprae_Br4923          ALIADMHHSGDKSMIRITATSVIVILVTLLLVYRSFITVILLLFTVGIES
                                    :  ** .  .: *:  *   :. **   **:****.:*  : :  * :  

Rv0676c|M.tuberculosis_H37Rv        LATRGGVAFLGFHRIIGLSTFATNLLVVLAIAAATDYAIFLIGRYQEARG
Mb0695c|M.bovis_AF2122/97           LATRGGVAFLGFHRIIGLSTFATNLLVVLAIAAATDYAIFLIGRYQEARG
MMAR_1005|M.marinum_M               LATRGGVAFLGYHRIIGLSTFATNLLVVLAIAAATDYAIFLIGRYQEARG
MUL_0757|M.ulcerans_Agy99           LATRGGVAFLGYHRIIGLSTFATNLLVVLAIAAATDYAIFLIGRYQEARG
Mflv_3435|M.gilvum_PYR-GCK          ATARGVVAFLGHHEIIGLSTFATNLLVTLAIAAATDYAIFLIGRYQEART
Mvan_3189|M.vanbaalenii_PYR-1       ATARGVVAFLGWHEIIGLSLFATNLLVTLAIAAATDYAIFLIGRYQEART
MSMEG_0225|M.smegmatis_MC2_155      AAARGVIAFLGYYEIIGLSTFATNLLVTLAIAAATDYAIFLIGRYQEARS
TH_3260|M.thermoresistible__bu      LTTRGVVAFLGYHNIIGLSTFATSLLVTLAIAIAVDYAIFLIGRYQEARS
MAV_2510|M.avium_104                SAARGMVAFLGYYKIIGLSTFATNLLVTLAIAAATDYAIFLIGRYQEARA
MAB_4382c|M.abscessus_ATCC_199      ASARGLVALLSYHNAFGLTSFATSLVVTLAIAAATDYAIFLIGRYQEARR
MLBr_02378|M.leprae_Br4923          AVARGVVALLGHTGLIGLSTFAVNLLTSLAIAAGTDYGIFITGRYQEARQ
                                      :** :*:*.    :**: **..*:. **** ..**.**: ******* 

Rv0676c|M.tuberculosis_H37Rv        LGQDRESAYYTMFGGTAHVVLGSGLTIAGATFCLSFTRLPYFQTLGVPLA
Mb0695c|M.bovis_AF2122/97           LGQDRESAYYTMFGGTAHVVLGSGLTIAGATFCLSFTRLPYFQTLGVPLA
MMAR_1005|M.marinum_M               LGQDRESAYYTMFGGTAHVVLGSGLTIAGATFCLSFTRLPYFQTLGVPLA
MUL_0757|M.ulcerans_Agy99           LGQDRESAYYTMFGGTAHVVLGSGLTIAGATFCLSFTRLPYFQTLGVPLA
Mflv_3435|M.gilvum_PYR-GCK          AGEDKETAYYTMFHGTAHVVLGSGLTIAGATFCLSFTRLPYFQTMGVPLA
Mvan_3189|M.vanbaalenii_PYR-1       NGEDKESAYYTMFHGTAHVVLGSGLTIAGATYCLSFTRLPYFQTLGVPLA
MSMEG_0225|M.smegmatis_MC2_155      VGESREQAYYTMFHSTAHVVLGSGMTIAGATLCLHFTRMPYFQSLGIPLA
TH_3260|M.thermoresistible__bu      VGADRATAYHTMFGGTAHVILASGLTIAGATFCLSFTRLPYFQSLGPPLA
MAV_2510|M.avium_104                VGESREDAYYTMYKGTAHVVAGSGMTIAGATFCLHFTNLPYFQTLGIPLA
MAB_4382c|M.abscessus_ATCC_199      AGEDRESAYYTMFHGTAHVVLASGLTIAGATFCLHFTRLPYFKTTGIPLS
MLBr_02378|M.leprae_Br4923          ANENKEAAFYTMYRGTFHVILGSGLTISGATFCLSFARMPYFQTLGVPCA
                                     . .:  *::**: .* **: .**:**:*** ** *:.:***:: * * :

Rv0676c|M.tuberculosis_H37Rv        IGMVIVVAAALTLGPAIIAVTSRFGKLLEPKRMARVRGWRKVGAAIVRWP
Mb0695c|M.bovis_AF2122/97           IGMVIVVAAALTLGPAIIAVTSRFGKLLEPKRMARVRGWRKVGAAIVRWP
MMAR_1005|M.marinum_M               IGMVIVVATALTLGPALIAVMSRFGKLLEPKRMARVRGWRKIGAAIVRWP
MUL_0757|M.ulcerans_Agy99           IGMVIVVATALTLGPALIAVMSRFGKLLEPKRMARVRGWRKIGAAIVRWP
Mflv_3435|M.gilvum_PYR-GCK          IGMFVVVMAGVVLMVACISVATRFGKLLEPKRAMRIRGWRKIGAAIVRWP
Mvan_3189|M.vanbaalenii_PYR-1       IGMFVVVMAGVILMVAMISVATRFGKLLEPKRAMRIRGWRKIGAAVVRWP
MSMEG_0225|M.smegmatis_MC2_155      IGMTVVVLTALAVGPAIITVASRFGKTLEPKRAMRTRGWRKVGAAVVRWP
TH_3260|M.thermoresistible__bu      IGMIVLIVTSLTMGPAIITVATRFG-LLEPKRAARVRFWRKVGASVVRWP
MAV_2510|M.avium_104                IGMVVVVAAALTLGPAVISVASRFRQTLEPRRTQRIRGWRKVGTVVVRWP
MAB_4382c|M.abscessus_ATCC_199      IGMAIVVAMALTLGPALISVASRFGNVLEPKGAGKARGWRRVGAATVRWP
MLBr_02378|M.leprae_Br4923          VGMLIAVAVALTLGPAVLTVGSRFG-LFEPKRLIKVRGWRRIGTVVVRWP
                                    :** : :  .: :  * ::* :**   :**:   : * **::*:  ****

Rv0676c|M.tuberculosis_H37Rv        GPILVGAVALALVGLLTLPGYRTNYNDRNYLPADLPANEGYAAAERHFSQ
Mb0695c|M.bovis_AF2122/97           GPILVGAVALALVGLLTLPGYRTNYNDRNYLPADLPANEGYAAAERHFSQ
MMAR_1005|M.marinum_M               GPILIGAVALALVGLLTLPGYKTNYNDRNYLPADLPANEGYSAAERHFSQ
MUL_0757|M.ulcerans_Agy99           GPILIGAVALALVGLLTLPGYKTNYNDRNYLPADLPANEGYSAAERHFSQ
Mflv_3435|M.gilvum_PYR-GCK          GPILVATMAITLVGLLALPGYKTNYNDRDYLPADLPANQGYAVADEHFDQ
Mvan_3189|M.vanbaalenii_PYR-1       GPILVATLAITLVGLLALPGYKTNYNDRTYLPADLPANEGYAVADRHFDQ
MSMEG_0225|M.smegmatis_MC2_155      GPILVAAVGLSMIGLLALPGYRTNYNDRDYQPADLPANSGYAAADRHFSQ
TH_3260|M.thermoresistible__bu      GPIMVTTVAVTLVGLLALPGYRTNYNDRNYLPASFPSNAGYEAAERHFDP
MAV_2510|M.avium_104                GPILVLTIGVALVGLLTLPGYRTNYNDRNYLPTDLPANEGYAAADRHFSQ
MAB_4382c|M.abscessus_ATCC_199      GAILVAAVTMALVGLLTLPGYHTTYNDRIYLPGQVPANVGYAAADRHFSK
MLBr_02378|M.leprae_Br4923          LPILITTCAIAMVGLLALPGYRTNYKDRAYLPASIPANQGFAAADRHFPQ
                                     .*:: :  ::::***:****:*.*:** * * ..*:* *: .*:.**  

Rv0676c|M.tuberculosis_H37Rv        ARMNPEVLMVESDHDMRNSADFLVINKIAKAIFAVEGISRVQAITRPDGK
Mb0695c|M.bovis_AF2122/97           ARMNPEVLMVESDHDMRNSADFLVINKIAKAIFAVEGISRVQAITRPDGK
MMAR_1005|M.marinum_M               ARMNPEVLMVESDHDMRNSSDFLVINKIAKAIFGVEGISRVQAITRPDGK
MUL_0757|M.ulcerans_Agy99           ARMNPEVLMVESDHDMRNSSDFLVINKIAKAIFGVEGISRVQAITRPDGK
Mflv_3435|M.gilvum_PYR-GCK          ARMNPELLMIESDHDLRNSADFLVIDKIAKALFRVEGIARVQAITRPDGK
Mvan_3189|M.vanbaalenii_PYR-1       ARMNPELLMIESDHDLRNSADFLVIDKIAKAIFKVEGIARVQAITRPDGK
MSMEG_0225|M.smegmatis_MC2_155      ARMNPELLMIESDHDLRNSADFLVIERIAKRVVGVPGVSRVQAITRPQGT
TH_3260|M.thermoresistible__bu      ARLNPELLLIESDHDLRNPADFLVIEKIAKAVFQVEGISRVQGITRPEGT
MAV_2510|M.avium_104                ARMNPEVLMIESDHDLRNSADFLVIDKIAKTVFRVPGIGRVQAITRPQGT
MAB_4382c|M.abscessus_ATCC_199      AKMNPDLLLVESDHDLRNPADFLVIDKIAKALARVRGIAQVQTITRPDGK
MLBr_02378|M.leprae_Br4923          ARMKPEILMIESDHDMRNPADFLILDKLARGIFRVPGISRVQAITRPDGT
                                    *:::*::*::*****:**.:***:::::*: :  * *:.:** ****:*.

Rv0676c|M.tuberculosis_H37Rv        PIEHTSIPFLISMQGTSQKLTEKYNQDLTARMLEQVNDIQSNIDQMERMH
Mb0695c|M.bovis_AF2122/97           PIEHTSIPFLISMQGTSQKLTEKYNQDLTARMLEQVNDIQSNIDQMERMH
MMAR_1005|M.marinum_M               PIEHTSIPFLISMQGTSQKLTEKYNQDLTTSMLQQVNDIQTNIDQMERMH
MUL_0757|M.ulcerans_Agy99           PIEHTSIPFLISMQGTSQKLTEKYNQDLTTSMLQQVNDIQTNIDQMERMH
Mflv_3435|M.gilvum_PYR-GCK          PIKHTSIPFQMSMQGTTQRLNEKYMQDRMADMLVQADEMANTIKTMEKMS
Mvan_3189|M.vanbaalenii_PYR-1       PIKHTSIPFQMSMQGTTQRLNEKYMQDRMADMLVQADEMANTIATMEKMS
MSMEG_0225|M.smegmatis_MC2_155      PIEHTSIPFTISMQGTTQTMNQKYMQDRMADMLVQADQMQVTVDTMTKMI
TH_3260|M.thermoresistible__bu      PIEHSSIPFMISQQGTLQILNQQYMQDRMADMLVQADEMQLMIDTMDKMI
MAV_2510|M.avium_104                PIEHTSIPFQISMQGVTQQMNQKYQQDQMADMLHQADMMQTTIDSMEKMQ
MAB_4382c|M.abscessus_ATCC_199      PIKHTSIPFNMSTANTAQTLTNDYSQANFANLLKQADAMQVTIDSMEKMQ
MLBr_02378|M.leprae_Br4923          AMDHTSIPFQISMQNAGQVQTMKYQKDRMNDLLRQAENMAETIASMRRMH
                                    .:.*:**** :*  .. *  . .* :     :* *.: :   :  * :* 

Rv0676c|M.tuberculosis_H37Rv        SLTQQMADVTHEMVIQMTGMVVDVEELRNHIADFDDFFRPIRSYFYWEKH
Mb0695c|M.bovis_AF2122/97           SLTQQMADVTHEMVIQMTGMVVDVEELRNHIADFDDFFRPIRSYFYWEKH
MMAR_1005|M.marinum_M               DLTQQMADVTHQMVIQMKGMVVDVEELRNHIADFDDFFRPIRSYFYWEKH
MUL_0757|M.ulcerans_Agy99           DLTQQMADVTHQMVIQMKGMVVDVEELRNHIADFDDFFRPIRSYFYWEKH
Mflv_3435|M.gilvum_PYR-GCK          GLTAQMADITHSMVTKMEGMVVDIEDLRDSIANFDDFFRPIRNYFYWEPH
Mvan_3189|M.vanbaalenii_PYR-1       NLTAQMADITHSMVSKMENMLTDIEDLRDSIANFDDFFRPIRNYFYWEPH
MSMEG_0225|M.smegmatis_MC2_155      ALMEQMRDTMNSMVGKMHGMVDDIKELRDNISDFDDFFRPIRNYLYWEPH
TH_3260|M.thermoresistible__bu      ALMEEMVETTDNMVRDMDEMAAHVAEMRDSISEFDDFFRPIRNYFYWEPH
MAV_2510|M.avium_104                SITVQMSNDMHVMVQKMHDMTIDINDLRNKMADFEDFFRPMRSYFYWEKH
MAB_4382c|M.abscessus_ATCC_199      AITQQMAEVTASMSANMKNTAQDINQLRDNMSNFDDQFRPIRNYFYWEKH
MLBr_02378|M.leprae_Br4923          QLMALLTENTHHILNDTVEMQKTTSKLRDEIANFDDFWRPIRSYFYWERH
                                     :   : :    :  .         .:*: :::*:* :**:*.*:*** *

Rv0676c|M.tuberculosis_H37Rv        CYDIPVCWSLRSVFDTLDGIDVMTEDINNLLPLMQRLDTLMPQLTAMMPE
Mb0695c|M.bovis_AF2122/97           CYDIPVCWSLRSVFDTLDGIDVMTEDINNLLPLMQRLDTLMPQLTAMMPE
MMAR_1005|M.marinum_M               CFDIPVCWSLRSVFDTLDGVDLMTEDINNLLPLMERLDTLMPQMTAMMPE
MUL_0757|M.ulcerans_Agy99           CFDIPVCWSLRSVFDTLDGVDLMTEDINNLLPLMERLDTLMPQMTAMMPE
Mflv_3435|M.gilvum_PYR-GCK          CYNIPVCWALRSVFDTLDGINIMTDDFKAIIPDMKRLDTLMPQMVALMPE
Mvan_3189|M.vanbaalenii_PYR-1       CYNIPVCWALRSVFDTLDGINVMTDDFREILPDMKRLDSLMPQMVALMPE
MSMEG_0225|M.smegmatis_MC2_155      CYNIPMCYSLRSIFDTMDGIDTMTADFEQIVPDMDRMNALIPVMIANMEP
TH_3260|M.thermoresistible__bu      CYNIPVCWAMRSVFDTLDGINTMTDDIQNMLPHMHRLNDLMPQMLTLLPT
MAV_2510|M.avium_104                CYDIPVCWSLRSVFDALDGIDTMTDDIQSLLPIMDHLDTLMPQMVALMPS
MAB_4382c|M.abscessus_ATCC_199      CFDIPMCWALRSVFDALDGISLMSDDFDTLVPDIQRMAGLMPQMVVLMPP
MLBr_02378|M.leprae_Br4923          CFNIPICWSFRSIFDALDGVDQIDERLNSIVGDIKNMDLLMPQMLEQFPP
                                    *::**:*:::**:**::**:. :   :  ::  :..:  *:* :   :  

Rv0676c|M.tuberculosis_H37Rv        MIQTMKSMKAQMLSMHSTQEGLQDQMAAMQEDSAAMGEAFDASRNDDSFY
Mb0695c|M.bovis_AF2122/97           MIQTMKSMKAQMLSMHSTQEGLQDQMAAMQEDSAAMGEAFDASRNDDSFY
MMAR_1005|M.marinum_M               MIQTMKSMKAQMLSMHSTQQGLQDQMAAMQEDSSAMGEAFDSSRNDDSFY
MUL_0757|M.ulcerans_Agy99           MIQTMKSMKAQMLSMHSTQQGLQDQMAAMQEDSSAMGEAFDSSRNDDSFY
Mflv_3435|M.gilvum_PYR-GCK          MIETMKTMRTMMLTMYQSQKGQQDQMAAMSEDADAMGEAFDDSMNDDSFY
Mvan_3189|M.vanbaalenii_PYR-1       MIETMKTMRTMMLTMYQSQKGQQDQMAAMSEDADAMGEAFDDSMNDDSFY
MSMEG_0225|M.smegmatis_MC2_155      MITTMKTMKTMMLTMQATNAGLQDQMAAMQENSTAMGEAFDKAKNDDSFY
TH_3260|M.thermoresistible__bu      TVATMKTMRSMLLTMQATNAGLQDQMAEMQENANAMGEAFDQARNDDSFY
MAV_2510|M.avium_104                MIENMKAMKTTMLTMYSTQKGLQDQQNEAQKNSNAMGKAFDASKNDDSFY
MAB_4382c|M.abscessus_ATCC_199      MIASMKEQKQIMLSQYQVQKAQQDQTMAMQANASAMGQAFDDAKNDDSFY
MLBr_02378|M.leprae_Br4923          MIESMESMRTIMLTMHSTMSGIFDQMNELSDNANTMGKAFDTAKNDDSFY
                                     : .*:  :  :*:      .  **    . :: :**:*** : ******

Rv0676c|M.tuberculosis_H37Rv        LPPEVFDNPDFQRGLEQFLSPDGHAVRFIISHEGDPMSQAGIARIAKIKT
Mb0695c|M.bovis_AF2122/97           LPPEVFDNPDFQRGLEQFLSPDGHAVRFIISHEGDPMSQAGIARIAKIKT
MMAR_1005|M.marinum_M               LPPEVFNNPDFKRGLEQFLSPDGHAVRFIISHEGDPMSQAGINHIDKIKT
MUL_0757|M.ulcerans_Agy99           LPPEVFNNPDFKRGLEQFLSPDGHAVRFIISHEGDPMSQAGINHIDKIKT
Mflv_3435|M.gilvum_PYR-GCK          LPPEIFENADFQRGLEQFLSPDGHAVRFIISHEGDPLSPEGVAKIDKIKT
Mvan_3189|M.vanbaalenii_PYR-1       LPPEIFENKDFQRGLEQFLSPDGHAVRFIISHEGDPLSPEGVAKIDKIKT
MSMEG_0225|M.smegmatis_MC2_155      LPPETFDNPDFKRGMKMFLSPDGHAVRFIISHEGDPMSPEGIQKIDDIKL
TH_3260|M.thermoresistible__bu      LPPEAFDNPDFQRGLEQFLSPDGHAVRFIISHQGDPMTPEGLAKIEPIKK
MAV_2510|M.avium_104                LPPETFNNKEFKKGMKNFISPDGHAVRFIISHDGDPMTQEGISHIGAIKK
MAB_4382c|M.abscessus_ATCC_199      LPPEAFETADFKSGIKLFVSPNGHAVRFTIFHQSDPLTEEGTSRVEPLKT
MLBr_02378|M.leprae_Br4923          LPPEVFKNTDFKRAMKSFLSSDGHAARFIILHRGDPASVAGIASINAIRT
                                    **** *.. :*: .:: *:*.:***.** * * .** :  *   :  :: 

Rv0676c|M.tuberculosis_H37Rv        AAKEAIKGTPLEGSAIYLGGTAAMFKDLSDGNTYDLMIAGISALCLIFII
Mb0695c|M.bovis_AF2122/97           AAKEAIKGTPLEGSAIYLGGTAAMFKDLSDGNTYDLMIAGISALCLIFII
MMAR_1005|M.marinum_M               AAKEAIKGTPLEGSTIYLGGTAAMFKDLSDGNTFDLMIAGISALCLIFII
MUL_0757|M.ulcerans_Agy99           AAKEAIKGTPLEGSTIYLGGTVAMFKDLSDGNTFDLMIAGISALCLIFII
Mflv_3435|M.gilvum_PYR-GCK          AAKEAVKGTPLEGSKIYLGGTAAVFKDMQDGNNYDLLIAGIAALGLIFII
Mvan_3189|M.vanbaalenii_PYR-1       AAKEAIKGTPLEGSKIYLGGTAATFKDMQDGNNYDLLIAGISALGLIFII
MSMEG_0225|M.smegmatis_MC2_155      AAKEAIKGTPLEGSKIYLGGTAATFKDMQEGANYDLIIAGIAALCLIFII
TH_3260|M.thermoresistible__bu      AAVEAIKGTPLEGSRVYLGGTAAVFKDMSDGTKYDLIIAAIAAVCLIFII
MAV_2510|M.avium_104                AAYEALKGTPLEGSKIYLAGTASIYKDLSDGNNYDLLIAGISSLCLIFII
MAB_4382c|M.abscessus_ATCC_199      AAEDAIKGTPLEGSSIYVGGSAALYKDMQEGADYDLLIAAVAALILIFLI
MLBr_02378|M.leprae_Br4923          AAEEALKGTPLEDTKIYLAGTAAVFKDIDEGANWDLVIAGISSLCLIFII
                                    ** :*:******.: :*:.*:.: :**:.:*  :**:**.:::: ***:*

Rv0676c|M.tuberculosis_H37Rv        MLITTRSVVAAAVIVGTVVLSLGASFGLSVLIWQHILGIELHWLVLAMAV
Mb0695c|M.bovis_AF2122/97           MLIITRSVVAAAVIVGTVVLSLGASFGLSVLIWQHILGIELHWLVLAMAV
MMAR_1005|M.marinum_M               MLIITRSVVAAAVIVGTVVLSLGASFGLSVLIWQHILGIELHWLVLAMAV
MUL_0757|M.ulcerans_Agy99           MLIITRSVVAAAVIVGTVVLSLGASFGLSVLIWQHVLGIELHWLVLAMAV
Mflv_3435|M.gilvum_PYR-GCK          MLILTRAVVAAAVIVGTVVLSLAASFGLSVLFWQHILGQPLHWMVLAMAV
Mvan_3189|M.vanbaalenii_PYR-1       MLILTRAIVAAAVIVGTVVLSLAASFGLSVLFWQHILGTELHWMVLAMAV
MSMEG_0225|M.smegmatis_MC2_155      MLIITRAVVASAVIVGTVVISLGSAFGLSVLIWQHLVGLELHWMVLAMAV
TH_3260|M.thermoresistible__bu      MLILTRAVVAAAVIVGTVTLSLAASFGVSVLIWQYIVGLEMHWMVFPMAL
MAV_2510|M.avium_104                MLIITRGVVASAVIVGTVLLSLGASFGLSVLIWQHLIGIELHWMVLAMSV
MAB_4382c|M.abscessus_ATCC_199      MVLLTRAVVAAAVIVGTVVLSLGASFGLSVLLWQHIIGTPLHWMVLPMAV
MLBr_02378|M.leprae_Br4923          MLIITRAFVAAAVIVGTVALSLGASFGLSVLLWQHILGIELHYLVLAMSV
                                    *:: **..**:******* :**.::**:***:**:::*  :*::*:.*::

Rv0676c|M.tuberculosis_H37Rv        IILLAVGADYNLLLVARLKEEIHAGINTGIIRAMGGSGSVVTAAGLVFAF
Mb0695c|M.bovis_AF2122/97           IILLAVGADYNLLLVARLKEEIHAGINTGIIRAMGGSGSVVTAAGLVFAF
MMAR_1005|M.marinum_M               IILLAVGADYNLLLVARLKEEIHAGINTGIIRAMGGSGSVVTAAGLVFAF
MUL_0757|M.ulcerans_Agy99           IILLAVGADYNLLLVARLKEEIHAGINTGIIRAMGGSGSVVTAAGLVFAF
Mflv_3435|M.gilvum_PYR-GCK          IILLAVGADYNLLLVSRLKEEIHAGIGTGIIRAMGGSGSVVTAAGLVFAL
Mvan_3189|M.vanbaalenii_PYR-1       IVLLAVGADYNLLLVSRLKEEIHAGIGTGIIRAMGGSGSVVTAAGLVFAL
MSMEG_0225|M.smegmatis_MC2_155      IVLLAVGADYNLLLVSRIKEEIHAGLDTGMIRAMGGSGSVVTAAGLVFAF
TH_3260|M.thermoresistible__bu      IILLAVGADYNLLVVARLREEIPAGLNTGMIRAMGGSGSVVTAAGLVFGL
MAV_2510|M.avium_104                IILLAVGADYNLLLVARFKEEIHAGLNTGIIRSMGGTGSVVTSAGLVFAF
MAB_4382c|M.abscessus_ATCC_199      IILLAVGADYNLLLVSRMKEELHAGLHTGTIRSMAGTGSVVTSAGLVFAF
MLBr_02378|M.leprae_Br4923          IVLLAVGSDYNLLLVSRFKQEIQAGLKTGIIRSMGGTGKVVTNAGLVFAF
                                    *:*****:*****:*:*:::*: **: ** **:*.*:*.*** *****.:

Rv0676c|M.tuberculosis_H37Rv        TMMSFAVSELTVMAQVGTTIGMGLLFDTLIVRSFMTPSIAALLGKWFWWP
Mb0695c|M.bovis_AF2122/97           TMMSFAVSELTVMAQVGTTIGMGLLFDTLIVRSFMTPSIAALLGKWFWWP
MMAR_1005|M.marinum_M               TMMSFAVSELTVMAQVGTTIGMGLLFDTLIVRSFMTPSIAALLGKWFWWP
MUL_0757|M.ulcerans_Agy99           TMMSFAVSELTVMAQVGTTIGMGLLFDTLIVRSFMTPSIAALLGKWFWWP
Mflv_3435|M.gilvum_PYR-GCK          TMMSMSVSELTVIGQVGTTIGLGLLFDTLVIRAFMTPSIAALLGPWFWWP
Mvan_3189|M.vanbaalenii_PYR-1       TMMSMAVSELTVIGQVGTTIGLGLLFDTLVIRAFMTPSIAALLGPWFWWP
MSMEG_0225|M.smegmatis_MC2_155      TMMSMAVSELAIIGQVGTTIGLGLLFDTLVIRSFMTPSIAALLGKWFWWP
TH_3260|M.thermoresistible__bu      TMMVMVVSDLTVMGQVGTTIGLGLLFDTFVVRSFMMPSIATLLGRWFWWP
MAV_2510|M.avium_104                TMMTMAVSELTVIGQVGTTIGLGLLFDTLIVRSLMTPSIAALLGKWFWWP
MAB_4382c|M.abscessus_ATCC_199      TMMGMMVSSFTVIGQIGTTIGLGLLFDTLVVRSFMTPSIASLLGRWFWWP
MLBr_02378|M.leprae_Br4923          TMASMVVSDLRVIGQVGTTIGLGLLFDTLIVRSFMMPSIAALLGRWFWWP
                                    **  : **.: ::.*:*****:******:::*::* ****:*** *****

Rv0676c|M.tuberculosis_H37Rv        QVVRQRPIPQPWPSPASARTFALV----
Mb0695c|M.bovis_AF2122/97           QVVRQRPVPQPWPSPASARTFALV----
MMAR_1005|M.marinum_M               QVVRQRPAPQPWPTPAPTP--ATTSV--
MUL_0757|M.ulcerans_Agy99           QVVRQRPAPQPWPTPAPTPPPATTSV--
Mflv_3435|M.gilvum_PYR-GCK          QRVRTRPVPAPWPRSGGLQSDPSEGVRA
Mvan_3189|M.vanbaalenii_PYR-1       QRVRTRPVPAPWPRPGGLQSDPSEGVKV
MSMEG_0225|M.smegmatis_MC2_155      QMVRRRPKPSPWPKPIQREPADAVN---
TH_3260|M.thermoresistible__bu      QFVRKRPVPQPWPSVPPRGPATTDRVSV
MAV_2510|M.avium_104                QRVRQRPVPSPWPKPAAQEREVLADA--
MAB_4382c|M.abscessus_ATCC_199      MVVRPRPRPQPWPQPLHAGAAEAVRA--
MLBr_02378|M.leprae_Br4923          QQGRTRPLLTVAAPVGLPPDRSLVYSD-
                                       * **     .