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TSRQEAILQASAAAIAENGVRGLRVSDIARVAGVSSGLLYYHFKDRDGLLAAALTYINDQAREYRQAASG SGVSRRQLIEHILGEIQDSPAVLENSLVWNELRACAVYEEAMREPLARTSQEWTRETAAAIRAAQDIGEV SESVDAECVASVLNALTEGLVSRWLSQEITAAEARAHLRATAEAMLPRSDRGPRKAVRA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_2543c | - | - | 100% (200) | TetR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_4360c | - | 2e-09 | 29.88% (164) | transcriptional regulator TetR |
| M. abscessus ATCC 19977 | MAB_2731 | - | 2e-09 | 23.86% (176) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0335 | - | 1e-08 | 23.94% (188) | TetR/AcrR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_0963 | - | 8e-10 | 26.98% (189) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0328 | - | 1e-08 | 23.94% (188) | TetR/AcrR family transcriptional regulator |
| M. leprae Br4923 | MLBr_01070 | - | 5e-09 | 21.23% (179) | putative TetR-family transcriptional regulator |
| M. marinum M | MMAR_0923 | - | 2e-07 | 26.94% (193) | transcriptional regulator |
| M. avium 104 | MAV_4754 | - | 3e-08 | 29.52% (166) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_0663 | - | 3e-10 | 27.71% (166) | TetR-family protein transcriptional regulator |
| M. thermoresistible (build 8) | TH_4573 | - | 2e-09 | 27.56% (156) | PUTATIVE putative transcriptional regulator, TetR family |
| M. ulcerans Agy99 | MUL_0675 | - | 2e-07 | 26.42% (193) | transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_3287 | - | 2e-10 | 32.52% (163) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_0923|M.marinum_M ------------------MPTAAERGAQTRAALMAAAVAVIAERGWGAAT
MUL_0675|M.ulcerans_Agy99 ------------------MPTAAERGAQTRAALMAAAVAVIAERGWGAAT
Mb0335|M.bovis_AF2122/97 ----------------------MQQQRTNRDKLLDGALACLRERGYGNTS
Rv0328|M.tuberculosis_H37Rv ----------------------MQQQRTNRDKLLDGALACLRERGYGNTS
Mflv_0963|M.gilvum_PYR-GCK --------MSSTTRTGRGRRAARPSGDDRESAILTTAEQLLEQRPLNDIS
MLBr_01070|M.leprae_Br4923 MIVVGNFTQSNYVPASRGRRSSQLSGDDREQAILAVAERLLAERPLGDFS
MAB_2543c|M.abscessus_ATCC_199 -------------------------MTSRQEAILQASAAAIAENGVRGLR
Mvan_3287|M.vanbaalenii_PYR-1 -----------MSHSETSRPKEDPRIGHSRRAILRAALAEFAANGYAGFR
MAV_4754|M.avium_104 ---MGQPQSQMEPESKLRQRTEGRLDRSRDPAILDAALAALAEHGYDATN
MSMEG_0663|M.smegmatis_MC2_155 ---------------MADPAPATENNEARRIQMLRTAAELICERGFSDTR
TH_4573|M.thermoresistible__bu -----------MATQRATADVEEQHESDRRDQILEAANACFAQLGIHRTS
:: : :
MMAR_0923|M.marinum_M TRMVAERAGLPPGLVHYHFASLNDLLIDAALQAAREEAAQVLDGLAG--D
MUL_0675|M.ulcerans_Agy99 TRMVAERAGLPPGLVHYHFASLNDLLIDAALQAAREEAAQVLDGLAG--D
Mb0335|M.bovis_AF2122/97 SRDIARAAGVNIASINYHFGSK-DALLDDALGRCFSTWNQRVQEAFD--H
Rv0328|M.tuberculosis_H37Rv SRDIARAAGVNIASINYHFGSK-DALLDDALGRCFSTWNQRVQEAFD--H
Mflv_0963|M.gilvum_PYR-GCK VDDLARGAGISRPTFYFYFSSK-DAVLLALLDRVIAEANARADAALGGRD
MLBr_01070|M.leprae_Br4923 VDELAKGAGISRPTFYFYFPSK-NAVLLSLLDDLNMKSRSAVEALA---E
MAB_2543c|M.abscessus_ATCC_199 VSDIARVAGVSSGLLYYHFKDR-DGLLAAALTYINDQAREYRQAASG---
Mvan_3287|M.vanbaalenii_PYR-1 MESVAARAGVGRSTVYRHWPDR-AALVADALAGLNRQPDPGHGDGAD---
MAV_4754|M.avium_104 MNDIAARAGVGKAAIYRRWSSK-AALMTDALIYWRPELLNDDAPDTG---
MSMEG_0663|M.smegmatis_MC2_155 IADVAKRAGVSSALVIYYFGTR-DRLLVDALRHSEESFYTAAEQMLAEVS
TH_4573|M.thermoresistible__bu VQDVARAANVSRGTVYRYFEDR-TILIEAAIEYGAQKFYQEIAAAMAKKS
:* *.: . : :: :
MMAR_0923|M.marinum_M SPSQGIDRLIDAVSSYDVDDRNQN-PAILVFGEMLLAATRYERLRMGLAE
MUL_0675|M.ulcerans_Agy99 SSSQGIDRLIDAVSSYDVDDRNQN-PAILVFGEMLLAATRYERLRMGLAE
Mb0335|M.bovis_AF2122/97 SRAAGPAGQILAVLEATVDSFEQIRPAVYACVESYAPALRSEALRERLAA
Rv0328|M.tuberculosis_H37Rv SRAAGPAGQILAVLEATVDSFEQIRPAVYACVESYAPALRSEALRERLAA
Mflv_0963|M.gilvum_PYR-GCK DRPLEPAGVWQ-AIKALFETFAAHRAVMLAGAAMRPNNPEVQRVWSHFMQ
MLBr_01070|M.leprae_Br4923 QLPADPAAVWRSAITAFFEVCGTHRAVAVAGAAAKATSPEVRRLWSTVMQ
MAB_2543c|M.abscessus_ATCC_199 --SGVSRRQLIEHILGEIQDSPAVLENSLVWNELRACAVYEEAMREPLAR
Mvan_3287|M.vanbaalenii_PYR-1 -----TAGQRAHVLLSHLAQALTDSPVSACIPALIHAAANDTDFRDRLHG
MAV_4754|M.avium_104 ----SLAGDLDAIVKRAKRNDNALISNDLVLRVALEAAHDPELATALNDL
MSMEG_0663|M.smegmatis_MC2_155 SLRERLSLLIRWTCVPD-GGTDDIPGAWGLWFDLWAQAFRHDEVKAGRIE
TH_4573|M.thermoresistible__bu TLAEQLGAMAETHAKILLDHRTRNRLMTDDAELMRHMIADADAAVRRTTE
MMAR_0923|M.marinum_M ILGDYRSALRQWLAD-----------------------QGGAIDP----E
MUL_0675|M.ulcerans_Agy99 ILGDYRSTLRQWLAD-----------------------QGGAIDP----E
Mb0335|M.bovis_AF2122/97 GYADVRQHSVDLAGAA---------------------LAGTDIAPPENLS
Rv0328|M.tuberculosis_H37Rv GYADVRQHSVDLAGAA---------------------LAGTDIAPPENLS
Mflv_0963|M.gilvum_PYR-GCK KWIDYTAASIRAERER---------------------GAAPDTLP----A
MLBr_01070|M.leprae_Br4923 QWIDYNTAAIQAERKC---------------------GVAPDTIP----A
MAB_2543c|M.abscessus_ATCC_199 TSQEWTRETAAAIRAA---------------------QDIGEVSES-VDA
Mvan_3287|M.vanbaalenii_PYR-1 FSAQRRRRLTDVISAG---------------------VTAGEFPA----T
MAV_4754|M.avium_104 ILFKGRRVLSAVLAQA---------------------ADRGEIDP----N
MSMEG_0663|M.smegmatis_MC2_155 LDARWRRMIIDALESAEPGELRSGVDAKLFALEFSALLDGLSIQVALDDP
TH_4573|M.thermoresistible__bu FLMPYVQQAKERGEVG----------------------SGVDVKAA---S
MMAR_0923|M.marinum_M ATAALMFAAIDGLVLHRVIDPRLRTLAIRPALRRLAGLPTAQTDERTPP-
MUL_0675|M.ulcerans_Agy99 ATAALMFAAIDGLVLHRVIDPRLRTLAIRPTLRRLAGLPTAQTDERTPS-
Mb0335|M.bovis_AF2122/97 TIVSVLMAVIDGLMIQWIADP-SATPRSTEVIRALASIGAVVTSQLR---
Rv0328|M.tuberculosis_H37Rv TIVSVLMAVIDGLMIQWIADP-SATPRSTEVIRALASIGAVVTSQLR---
Mflv_0963|M.gilvum_PYR-GCK EDLAIALNLMNERIMLSAFASEQAAVTADRLVGTLAHIWVSSIYGTPRA-
MLBr_01070|M.leprae_Br4923 EDLAVALQLMTERVMAATFSDEKPLIPDKKVIDTLVHIWLASIYGS----
MAB_2543c|M.abscessus_ATCC_199 ECVASVLNALTEGLVSRWLSQEITAAEARAHLRATAEAMLPRSDRGPRKA
Mvan_3287|M.vanbaalenii_PYR-1 VDPETASVALSGGVFYRCLMT--ADAADADFVAGLLDAVLGR--------
MAV_4754|M.avium_104 RDWSLVADVLTAMGLLRAISG---QRVDGKFVRRVIDTLILPAVRAAPE-
MSMEG_0663|M.smegmatis_MC2_155 EVDAEVAYQIAMRFCERELDLPPKKASGRKPAKATKSAKTTKSAKTSQPR
TH_4573|M.thermoresistible__bu EWLARIIYSFTTVNEGLTFDMSKPATVRRYVERFAVNGLR----------
:
MMAR_0923|M.marinum_M ---
MUL_0675|M.ulcerans_Agy99 ---
Mb0335|M.bovis_AF2122/97 ---
Rv0328|M.tuberculosis_H37Rv ---
Mflv_0963|M.gilvum_PYR-GCK ---
MLBr_01070|M.leprae_Br4923 ---
MAB_2543c|M.abscessus_ATCC_199 VRA
Mvan_3287|M.vanbaalenii_PYR-1 ---
MAV_4754|M.avium_104 ---
MSMEG_0663|M.smegmatis_MC2_155 RR-
TH_4573|M.thermoresistible__bu ---