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ADPAPATENNEARRIQMLRTAAELICERGFSDTRIADVAKRAGVSSALVIYYFGTRDRLLVDALRHSEES FYTAAEQMLAEVSSLRERLSLLIRWTCVPDGGTDDIPGAWGLWFDLWAQAFRHDEVKAGRIELDARWRRM IIDALESAEPGELRSGVDAKLFALEFSALLDGLSIQVALDDPEVDAEVAYQIAMRFCERELDLPPKKASG RKPAKATKSAKTTKSAKTSQPRRR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_0663 | - | - | 100% (235) | TetR-family protein transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_5850 | - | 6e-09 | 40.00% (85) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_1506 | - | 8e-09 | 27.98% (193) | transcriptional regulator, TetR family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0798 | - | 3e-08 | 36.84% (95) | hypothetical protein Mb0798 |
| M. gilvum PYR-GCK | Mflv_1610 | - | 1e-08 | 37.93% (87) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0775 | - | 3e-08 | 36.84% (95) | hypothetical protein Rv0775 |
| M. leprae Br4923 | MLBr_00717 | - | 3e-06 | 32.81% (64) | putative TetR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_2543c | - | 2e-10 | 27.71% (166) | TetR family transcriptional regulator |
| M. marinum M | MMAR_4918 | - | 9e-08 | 34.65% (101) | hypothetical protein MMAR_4918 |
| M. avium 104 | MAV_0847 | - | 1e-06 | 38.57% (70) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_1265 | - | 3e-09 | 40.00% (80) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_0488 | - | 8e-08 | 34.65% (101) | hypothetical protein MUL_0488 |
| M. vanbaalenii PYR-1 | Mvan_5148 | - | 2e-08 | 37.93% (87) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_4918|M.marinum_M -MGVTAAVTPKGERRRYALVSAAAELLGEGGFEAVRHRAVARRAGLPLAS
MUL_0488|M.ulcerans_Agy99 ---MTAAVTPKGERRRYALVSAAAELLGEGGFEAVRHRAVARRAGLPLAS
Mb0798|M.bovis_AF2122/97 -MGVTAAVTPKGERRRYALVSAAAELLGEGGFEAVRHRAVARRAGLPLAS
Rv0775|M.tuberculosis_H37Rv -MGVTAAVTPKGERRRYALVSAAAELLGEGGFEAVRHRAVARRAGLPLAS
Mflv_1610|M.gilvum_PYR-GCK MLKVTAAVTPKGERRRYALVSAAADLLCEGGFDAVRHRAVARRAGLPLAS
Mvan_5148|M.vanbaalenii_PYR-1 ---MTAAVTPKGERRRYALVSAAADLLCEGGFDAVRHRAVARRAGLPLAS
TH_1265|M.thermoresistible__bu -------VTPKGERRRDALISAAAELLCEGGFDAVRHRAVARRAGLPLAS
MAB_2543c|M.abscessus_ATCC_199 -----------MTSRQEAILQASAAAIAENGVRGLRVSDIARVAGVSSGL
MSMEG_0663|M.smegmatis_MC2_155 -MADPAPATENNEARRIQMLRTAAELICERGFSDTRIADVAKRAGVSSAL
MAV_0847|M.avium_104 ------------------MIEATARLMREEGYAAATSRRVAAEAGVKQAL
MLBr_00717|M.leprae_Br4923 --MTTARRRLSPEDRRAELLALGAEVFGKRPYDEVRIDEIAERAGVSRAL
:: * : : :* **: .
MMAR_4918|M.marinum_M TTYYFSSLDDLIARAVEHVGMIEVAQLRARVNALSRRRRGPETTADVLVD
MUL_0488|M.ulcerans_Agy99 TTYYFSSLDDLVARAVEHVGMIEVAQLRARVNALSRRRRGPETTADVLVD
Mb0798|M.bovis_AF2122/97 TTYYFSSLDDLIARAVEHIGMIEVAQLRARVSALSRRRRGPETTAVVLVD
Rv0775|M.tuberculosis_H37Rv TTYYFSSLDDLIARAVEHIGMIEVAQLRARVSALSRRRRGPETTAVVLVD
Mflv_1610|M.gilvum_PYR-GCK TTYYFSSLDDLIANAVEHVGSRETEQLRHRVAALSRRRRGAESTADILVD
Mvan_5148|M.vanbaalenii_PYR-1 TTYYFSSLDDLIAKAVEHVGTRESEQLRTRVETLSRRRRGAESTADIIVD
TH_1265|M.thermoresistible__bu TTYYFSSLDDLIVQAVTHIGARETRQLEQRVAAVARRRRGAETTADVLVD
MAB_2543c|M.abscessus_ATCC_199 LYYHFKDRDGLLAAALTYIN-DQAREYRQAASGSGVSRR------QLIEH
MSMEG_0663|M.smegmatis_MC2_155 VIYYFGTRDRLLVDALRHSEESFYTAAEQMLAEVSSLRER---LSLLIRW
MAV_0847|M.avium_104 VYYYFPTMDDLFVEVLRAGAESALTRMRALLTEDD---------PLQALW
MLBr_00717|M.leprae_Br4923 MYHYFPDKRAFFAAVVKDEADRLYAATNIPPPAGLTMFEEVRVGVLAYMA
::* :.. .: .
MMAR_4918|M.marinum_M LLVGDVSSPGLAEQLISRYERNIACTRLPALRESMRRSLRQRAEAVAEAI
MUL_0488|M.ulcerans_Agy99 LLVGDVSSPGLAEQLISRYERNIACTRLPALRESMRRSLRQRAEAVAEAI
Mb0798|M.bovis_AF2122/97 LLVGEMSSPGLAEQLISRYERHIACTRLPDLRESMRRSLRQRAEAVAEAI
Rv0775|M.tuberculosis_H37Rv LLVGEMSSPGLAEQLISRYERHIACTRLPDLRESMRRSLRQRAEAVAEAI
Mflv_1610|M.gilvum_PYR-GCK LLVGDNP-ERVTEQMISRYERYIACARQPGLRDIQRRILRQRSDAVVEVV
Mvan_5148|M.vanbaalenii_PYR-1 LLVGDNP-ERVTEQIISRYERYIACARQPGLRDIQRRILRQRSDAVVEVV
TH_1265|M.thermoresistible__bu VLVGTASGITATEELISRYERYIACARQPALRDIQRQIRKQRTDAVVKVV
MAB_2543c|M.abscessus_ATCC_199 ILGEIQDSPAVLENSLVWNELRACAVYEEAMREPLARTSQEWTRETAAAI
MSMEG_0663|M.smegmatis_MC2_155 TCVPDGGTDDIPGAWGLWFDLWAQAFRHDEVKAGRIELDARWRRMIIDAL
MAV_0847|M.avium_104 LMNSDTALTALNAEFMALANHRKAIG--AELKAYAERVRDIETAAATMVL
MLBr_00717|M.leprae_Br4923 YHKQNPEAAWAAYVGLGRSDPVLLGIDDEAKNRQMEHIMSRIGDVVSVVP
: . . .
MMAR_4918|M.marinum_M ERS------GRSVRIELVCTLICAVDGSVVSALVE-GRDPRAAALATVVD
MUL_0488|M.ulcerans_Agy99 ERS------GRSVRIELVCTLICAVDGSVVSALVE-GRDPRAAALATVV-
Mb0798|M.bovis_AF2122/97 ERS------GRSAQIELVCTLICAVDGSVVSALVE-GRDPRAAALATVVD
Rv0775|M.tuberculosis_H37Rv ERS------GRSAQIELVCTLICAVDGSVVSALVE-GRDPRAAALATVVD
Mflv_1610|M.gilvum_PYR-GCK ERS------GRSVRAELVTALVCAVDGAVVAALVGDGDGPRATARATLID
Mvan_5148|M.vanbaalenii_PYR-1 ERS------GRSVRTELVTALVCAVDGAVVAALVGDGEGPRATARATLID
TH_1265|M.thermoresistible__bu ERS------GRAVRPELVSALVCAVDGAVVAALVGDGDGPRATARSTLID
MAB_2543c|M.abscessus_ATCC_199 RAAQDIGEVSESVDAECVASVLNALTEGLVSRWLS-QEITAAEARAHLRA
MSMEG_0663|M.smegmatis_MC2_155 ESAEP-GELRSGVDAKLFALEFSALLDGLSIQVALDDPEVDAEVAYQIAM
MAV_0847|M.avium_104 RAN--------GIDLEEYPPVAISMLIAQAARSLCNEKAVGVTQGHDELR
MLBr_00717|M.leprae_Br4923 ESK---LHPDIERDLRVIVHGWLAFTFEVCRQRIMDPSTDADRLADSCAH
. . :.
MMAR_4918|M.marinum_M ---LIDVLAPVDQRPVQV----------------------
MUL_0488|M.ulcerans_Agy99 ----------------------------------------
Mb0798|M.bovis_AF2122/97 ---LIDVLAPVDQRPVPF----------------------
Rv0775|M.tuberculosis_H37Rv ---LIDVLAPVDQRPVPF----------------------
Mflv_1610|M.gilvum_PYR-GCK ---VIDVLAPFN----------------------------
Mvan_5148|M.vanbaalenii_PYR-1 ---VIDVLAPFN----------------------------
TH_1265|M.thermoresistible__bu ---VIDVLAPYA----------------------------
MAB_2543c|M.abscessus_ATCC_199 ---TAEAMLPRSDRGPRKAVRA------------------
MSMEG_0663|M.smegmatis_MC2_155 RFCERELDLPPKKASGRKPAKATKSAKTTKSAKTSQPRRR
MAV_0847|M.avium_104 AFVQRQLSRLTAPAVASTTSA-------------------
MLBr_00717|M.leprae_Br4923 ALLDAIARVPEISKELADAMAIARQPPQ------------