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MSHSETSRPKEDPRIGHSRRAILRAALAEFAANGYAGFRMESVAARAGVGRSTVYRHWPDRAALVADALA GLNRQPDPGHGDGADTAGQRAHVLLSHLAQALTDSPVSACIPALIHAAANDTDFRDRLHGFSAQRRRRLT DVISAGVTAGEFPATVDPETASVALSGGVFYRCLMTADAADADFVAGLLDAVLGR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_3287 | - | - | 100% (195) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_2727 | - | 2e-12 | 31.18% (186) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_5223 | - | 4e-12 | 29.83% (181) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1199c | - | 7e-12 | 28.41% (176) | transcriptional regulatory protein |
| M. gilvum PYR-GCK | Mflv_3506 | - | 2e-84 | 78.46% (195) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv1167c | - | 7e-12 | 28.41% (176) | transcriptional regulatory protein |
| M. leprae Br4923 | MLBr_00316 | - | 3e-05 | 44.90% (49) | putative TetR/AcrR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_3462c | - | 1e-16 | 33.89% (180) | TetR family transcriptional regulator |
| M. marinum M | MMAR_2639 | - | 3e-11 | 30.60% (183) | hypothetical protein MMAR_2639 |
| M. avium 104 | MAV_2958 | - | 8e-12 | 30.60% (183) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_5190 | - | 2e-15 | 33.33% (171) | TetR-family protein transcriptional regulator |
| M. thermoresistible (build 8) | TH_3283 | - | 2e-09 | 25.93% (189) | PUTATIVE putative transcriptional regulator, TetR family |
| M. ulcerans Agy99 | MUL_2482 | - | 3e-09 | 26.90% (171) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_3287|M.vanbaalenii_PYR-1 --------------------------MSHSETSRPKEDPRIGHSRRAILR
Mflv_3506|M.gilvum_PYR-GCK --------------------------MSHNVTSSAREDPRIGHSRRVILR
TH_3283|M.thermoresistible__bu -------------------------MPGSGARSP--GRPRDPALDDAIRA
MUL_2482|M.ulcerans_Agy99 ----------------------MKADPSSLDKAPGAGRPRDPRIDFAILS
Mb1199c|M.bovis_AF2122/97 -------------------------MTVSAPAKANPYRRRGEVLERALYD
Rv1167c|M.tuberculosis_H37Rv -------------------------MTVSAPAKANPYRRRGEVLERALYD
MMAR_2639|M.marinum_M MTLSGEPGYSYTGLVSSDNADPPDAGTGAPVPAGRRSDRRPAQTIRKVLE
MAV_2958|M.avium_104 --------------MPEDASSPVIAG-GAPTGPARRSDRRPGQTIRKVLD
MAB_3462c|M.abscessus_ATCC_199 -----------------MNETVGPGEVDTPRRHFGNRHGRSEAAREAVLH
MSMEG_5190|M.smegmatis_MC2_155 -------------------------------MAGERPGGRTAAVRRAVLS
MLBr_00316|M.leprae_Br4923 ------------------MSVPRSGLSVQMAQPARPLRADAARNRARILG
:
Mvan_3287|M.vanbaalenii_PYR-1 AALAEFAANGYAGFRMESVAARAGVGRSTVYRHWPDRAALVADALAGLNR
Mflv_3506|M.gilvum_PYR-GCK AALAEFAAHGYTGFRMESVAARAEVGRSTVYRHWPDKGALIADALAGLSR
TH_3283|M.thermoresistible__bu AARDVVVEHGYDATTLALIADRAGVSVPTIYRRWQHKHELIEEAVLHLDT
MUL_2482|M.ulcerans_Agy99 ATMELLVQIGYSNLSLAAVAERAGTTKSALYRRWSSKAELVHEAAFPVTP
Mb1199c|M.bovis_AF2122/97 ATLAELESAGYGGLTMEGIAARAQTGKAALYRRWAGKRELVLAAVQYALP
Rv1167c|M.tuberculosis_H37Rv ATLAELESAGYGGLTMEGIAARAQTGKAALYRRWAGKRELVLAAVQYALP
MMAR_2639|M.marinum_M AGLDELRATSFANLTMRAVAARAGVSPASAYTYFPSKSALVAAVYLRLLR
MAV_2958|M.avium_104 AGLQELRESSYAGLTMRAVATRAGVSPASAYTYFPSKSALVAAVYLRFLR
MAB_3462c|M.abscessus_ATCC_199 AADDLLVARGYAGVTMEGIAKAAGVAKQTVYRWWSSKVDVLMDVFLEDAA
MSMEG_5190|M.smegmatis_MC2_155 AAEDLLIEAGFDGLELTVVAERAGVGKSTVYRRWGTVPALVADLLTDMAE
MLBr_00316|M.leprae_Br4923 VAYEAFATEGLS-VPIDEIARRAGVGAGTVYRHFPTKEALCAAVIGDRMP
. . . : :* * . : * : :
Mvan_3287|M.vanbaalenii_PYR-1 QPDPGHGDGADTAGQRAHVLLSHLAQALTDSPVSACIPALIHAAANDTDF
Mflv_3506|M.gilvum_PYR-GCK QPDPAHEDSAATARRRAHILLNHLAQALTDSPVSACVPALIHAAANDDAF
TH_3283|M.thermoresistible__bu FELPEPTGDLEADLGTWVRLFLTVAMEPAARAAVP--GLMSAYSRNPDDY
MUL_2482|M.ulcerans_Agy99 SALSAPAGDFAGDIRMMVAATRDVFTTPVVRAALP--GLVADMTAEADLN
Mb1199c|M.bovis_AF2122/97 -PVPEPRADRSAREN-LLAVFTANCEILAGKTALPSMEIVSQLLHEPELR
Rv1167c|M.tuberculosis_H37Rv -PVPEPRADRSAREN-LLAVFTANCEILAGKTALPSMEIVSQLLHEPELR
MMAR_2639|M.marinum_M -DLPLHTDVNDTTKTRVSATMRDMAMVVADEPELTAACGTALMADDP---
MAV_2958|M.avium_104 -DLPVHTDVNETAQRRVSATLRDMAVVVADEPELTAACGAALMADDP---
MAB_3462c|M.abscessus_ATCC_199 CQLDPP-DLGGLEADLRHHLSATAQFLAADDAGAVFRALIGQSQHDGQLA
MSMEG_5190|M.smegmatis_MC2_155 QSLPRA-DTGSLRGDLQANARLVRRTLADARQGRLFKAMIAAATCDPR-T
MLBr_00316|M.leprae_Br4923 -HLVDDGYVLLKSAGPGEALFTYLRSLVLHWGATDRGLVDALAGAGGIDI
Mvan_3287|M.vanbaalenii_PYR-1 RDRLHGFSAQRRRRLTDVISAGVTAGEFPATVDPETASVALSGGVFYRCL
Mflv_3506|M.gilvum_PYR-GCK RDRLHRFSAQRRQRLTATIAEGVASGEFPPTVDPEIASAALSGAVFYRAL
TH_3283|M.thermoresistible__bu RRLMTRGELPVRAAIAAMLERAKAAGQAAPDCDPDAVFELIRGATFLRAL
MUL_2482|M.ulcerans_Agy99 ARVLSR-FTELFATVRIRLQEAVDRGEAHPDVDPNRMIELIGGATMLRVL
Mb1199c|M.bovis_AF2122/97 AIFINSVWAPRLRIVESILQAGVRSGEIDPATLTPMTARIGPALIHQHVL
Rv1167c|M.tuberculosis_H37Rv AIFINSVWAPRLRIVESILQAGVRSGEIDPATLTPMTARIGPALIHQHVL
MMAR_2639|M.marinum_M --AVQPLRAQIGEEVARRIGAALGPG-WPRSVKSTLQMTFSGALMTARFL
MAV_2958|M.avium_104 --AVKPLREQIGEEVSRRIAAALGPG-WPRAVKSTLQMTFSGALMTARFV
MAB_3462c|M.abscessus_ATCC_199 DDFRGRYLREQQARDQIPIARAVARGELPADVDVAHVAEQLVAPLYYRVI
MSMEG_5190|M.smegmatis_MC2_155 AEALEDFYARRIAEWSGCVTDAIARGEAPAGTDAAAAIRQVSAPLYYQFL
MLBr_00316|M.leprae_Br4923 LGVAPDAEDAFLTILSDLLYAAQYAGTARTDVGVREVKSILVG---CQAM
: . * . : :
Mvan_3287|M.vanbaalenii_PYR-1 MTADAADADFVAGLLDAVLGR----------
Mflv_3506|M.gilvum_PYR-GCK MTADAPDTDFVADLLDEVLGR----------
TH_3283|M.thermoresistible__bu THSDEDAEAFCTRITEAVLRAVRS-------
MUL_2482|M.ulcerans_Agy99 LYPDQMLDEAWVDQTTAILVHGVTR------
Mb1199c|M.bovis_AF2122/97 FTGSPPDREQLTRIIDAMILTTGERRES---
Rv1167c|M.tuberculosis_H37Rv FTGSPPDREQLTRIIDAMILTTGERRES---
MMAR_2639|M.marinum_M SYEEIAG--QLDEAVNLILGAAVA-------
MAV_2958|M.avium_104 SFAEISG--QLDEAVDLILGAARAS------
MAB_3462c|M.abscessus_ATCC_199 VTGETVDAAFVDRIVEDFLRRRE--------
MSMEG_5190|M.smegmatis_MC2_155 TSTKRLTTADADRAAEAAVAAIDAGVYTARG
MLBr_00316|M.leprae_Br4923 EAYNSALAERVTDVVVDGLRAAR--------
. :