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GQPQSQMEPESKLRQRTEGRLDRSRDPAILDAALAALAEHGYDATNMNDIAARAGVGKAAIYRRWSSKAA LMTDALIYWRPELLNDDAPDTGSLAGDLDAIVKRAKRNDNALISNDLVLRVALEAAHDPELATALNDLIL FKGRRVLSAVLAQAADRGEIDPNRDWSLVADVLTAMGLLRAISGQRVDGKFVRRVIDTLILPAVRAAPE*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_4754 | - | - | 100% (210) | transcriptional regulator, TetR family protein |
| M. avium 104 | MAV_3866 | - | 5e-16 | 32.24% (183) | transcriptional regulator, TetR family protein |
| M. avium 104 | MAV_5165 | - | 2e-14 | 35.15% (165) | transcriptional regulator, TetR family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1581 | - | 3e-14 | 30.39% (181) | regulatory protein |
| M. gilvum PYR-GCK | Mflv_3021 | - | 2e-17 | 31.07% (206) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv1556 | - | 3e-14 | 30.39% (181) | regulatory protein |
| M. leprae Br4923 | MLBr_00815 | - | 3e-05 | 43.40% (53) | putative TetR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_3151 | - | 4e-46 | 48.45% (194) | TetR family transcriptional regulator |
| M. marinum M | MMAR_1695 | - | 1e-14 | 31.52% (184) | regulatory protein |
| M. smegmatis MC2 155 | MSMEG_0465 | - | 7e-75 | 70.05% (197) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_4110 | - | 4e-13 | 28.00% (175) | PUTATIVE putative transcriptional regulator, TetR family |
| M. ulcerans Agy99 | MUL_1934 | - | 7e-15 | 31.52% (184) | regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_2727 | - | 6e-16 | 30.98% (184) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MAV_4754|M.avium_104 MGQPQSQMEPESKLRQRTEGR-----------------LDRSRDPAILDA
MSMEG_0465|M.smegmatis_MC2_155 ------MKATDSKLRQRTDGR-----------------LDRTRDPAILDA
MAB_3151|M.abscessus_ATCC_1997 ------MTKNAATQRQRTSGR-----------------LNRSLDIAILEA
Mb1581|M.bovis_AF2122/97 ------MVGAVTQIADRPTDP----------------SPWSPRETELLAV
Rv1556|M.tuberculosis_H37Rv ------MVGAVTQIADRPTDP----------------SPWSPRETELLAV
MMAR_1695|M.marinum_M ----------MTQTADRSAQV----------------SPWSPREAELLAV
MUL_1934|M.ulcerans_Agy99 -------MGAMTQTADRSAQV----------------SPWSPREAELLAV
Mflv_3021|M.gilvum_PYR-GCK ------MCVVSDPRSDPPSAPL--------------KSRRTAREAQLLTI
Mvan_2727|M.vanbaalenii_PYR-1 ------------------MGR----------------RRGAELDAAIRAA
TH_4110|M.thermoresistible__bu ------VTATDAAATGRAAARG--------------RPRDPALDSAILDA
MLBr_00815|M.leprae_Br4923 ---MNNLAKAAQRRTVRPIDRGRLSDDIATPNQRSNRLSRDKRRGQLLIV
:
MAV_4754|M.avium_104 ALAALAEHGYDATNMNDIAARAGVGKAAIYRRWSSKAALMTDALIYWRPE
MSMEG_0465|M.smegmatis_MC2_155 ALAALAENGYAGTNMDDIASRAGVGKAAIYRRWSSKAALITDALVYWKPA
MAB_3151|M.abscessus_ATCC_1997 AFVTLAEQGYDAMSMDNIAARAGVGKAAIYRRWSSKAALTADAILHGRPS
Mb1581|M.bovis_AF2122/97 TLRLLQEHGYDRLTVDAVAASARASKATVYRRWPSKAELVLAAFIEG---
Rv1556|M.tuberculosis_H37Rv TLRLLQEHGYDRLTVDAVAASARASKATVYRRWPSKAELVLAAFIEG---
MMAR_1695|M.marinum_M TLQLLQEHGYDRLTIDAVANTARASKATVYRRWPSKAELVLAAFIEG---
MUL_1934|M.ulcerans_Agy99 TLQLLQEHGYDRLTIDAVANTARASKATVYRRWPSKAELVLAAFIEG---
Mflv_3021|M.gilvum_PYR-GCK TLQQLQQHGYDRLTVEAVATQAKASKATLYRRWPSKSDLVLAAFVEG---
Mvan_2727|M.vanbaalenii_PYR-1 VLELLAEHGPDGVTMDAVAVTAQTSKPVLYRRWPDRRALLRDTLLGIAT-
TH_4110|M.thermoresistible__bu ALEIFVEQGISALSIEQVARRAGVGKPTIYRRWSDKEQLVADAIEHRVS-
MLBr_00815|M.leprae_Br4923 ASDVFVDHGYHAAGMDEIADRAGVSKPVLYQHFSSKLELYLAVLERHMN-
. : ::* :: :* * ..*..:*:::..: * .:
MAV_4754|M.avium_104 L-LNDDAPDTGSLAGDLDAIV---KRAKRNDNALISNDLVLRVALEAAHD
MSMEG_0465|M.smegmatis_MC2_155 L-LIDDIPDTGSLEGDLNEIA---ERAARNADERITYDLILRVAVEAMND
MAB_3151|M.abscessus_ATCC_1997 LGKLDEVPDTGSLRGDLHSLY---EARDFGDDQVLTGNLLAGIIAEAVND
Mb1581|M.bovis_AF2122/97 IRQVAVPPNTGNLRDDLLRLG---ELICREVGQHAS--TIRAVLVEVSRN
Rv1556|M.tuberculosis_H37Rv IRQVAVPPNTGNLRDDLLRLG---ELICREVGQHAS--TIRAVLVEVSRN
MMAR_1695|M.marinum_M VRQVAVAPNTGSLRDDLVKIG---EGICGQAHQQAS--TIRAVLVEVSRH
MUL_1934|M.ulcerans_Agy99 VRQVAVAPNTGSLRDDLVKIG---EGICGQAHQQAS--TIRAVLVEVSRH
Mflv_3021|M.gilvum_PYR-GCK TRLAAVPPRTGSLRDDLLRVG---ASVCQQACEHAS--TMRAVLNEMSHN
Mvan_2727|M.vanbaalenii_PYR-1 --SAFPTVDTGGFRGDMLAVL---RAWAALFTGDSA-ALMRSAIGAVTAD
TH_4110|M.thermoresistible__bu AELAWPTPAEASVSDPYELVRRNISAAARTAADPAFRGLIAAIYGSAVTH
MLBr_00815|M.leprae_Br4923 -NLVSSVQQALRTTTNNRQRLHAAVQAFFDFIEHDGQGYRLIFENDNITE
.
MAV_4754|M.avium_104 PELATALNDLILFKGRRVLSAVLAQAADRGEIDPNRDWSLVADVLTAMGL
MSMEG_0465|M.smegmatis_MC2_155 SQLASALDDLTLLRGRRTMTAILKNATARGEIAPDTDWSLVPDVLTAMLL
MAB_3151|M.abscessus_ATCC_1997 PTLAAALDDLLVSQTHKRMELVFARAVERGEITQGRDLSLVYDIPLGLSL
Mb1581|M.bovis_AF2122/97 PALNDVLQHQFVDHRKALIQYILQQAVDRGEISSAAISDELWDLLPGYLI
Rv1556|M.tuberculosis_H37Rv PALNDVLQHQFVDHRKALIQYILQQAVDRGEISSAAISDELWDLLPGYLI
MMAR_1695|M.marinum_M PALSDALQRQFVDQRKALIQQVLQQAVDRGEITQAAITDELWDLLPGYLI
MUL_1934|M.ulcerans_Agy99 PALSDALQRQFVDQRKALIQQVLQQAVDRGEITQAAITDELWDLLPGYLI
Mflv_3021|M.gilvum_PYR-GCK PDLRKAMQDEFVHQHKLVIDEVLAEAVQRGEIDATAISDEIYDLLPGYLV
Mvan_2727|M.vanbaalenii_PYR-1 PELAATFRTDVIGARKQEMDAIITRGVQRGEVRADVPVDLVRELGQSVLW
TH_4110|M.thermoresistible__bu PALLRTYWEHYILPRRTAAIALLRRARDLGTVAADADLDVLVDMLAGAVT
MLBr_00815|M.leprae_Br4923 PRVAAQVR-VATESCIDAVFALISADSRLDPHRARMVAVGLVGISVDCAR
. : :: . : :
MAV_4754|M.avium_104 LRAISGQR-VDGKFVRRVIDTLILP------AVRAAPE--
MSMEG_0465|M.smegmatis_MC2_155 MRAIRGER-VDANYVRKVIDTVIVP------AVRATAY--
MAB_3151|M.abscessus_ATCC_1997 TAALKRTV-IDETYMHRMVEEVILP------LVQAPTTHT
Mb1581|M.bovis_AF2122/97 FRSIIPNRPPTQDTVQALVDDVILP-----SLTRSTG---
Rv1556|M.tuberculosis_H37Rv FRSIIPNRPPTQDTVQALVDDVILP-----SLTRSTG---
MMAR_1695|M.marinum_M FRSIIPNRPPTPHTVQLLVDDFIMP-----GLTQATG---
MUL_1934|M.ulcerans_Agy99 FRSIIPNRPPTPHTVQLLVDDFIMP-----GLTQATG---
Mflv_3021|M.gilvum_PYR-GCK FRALVSARPPTLKSVRTLVDKVLLPSLGHRGLSKPDGQ--
Mvan_2727|M.vanbaalenii_PYR-1 HRLLISGDPIDDEVVTRLVDEVLIP------VTRPYYEV-
TH_4110|M.thermoresistible__bu YRVLQPEP-PSARQLRCYLEVAYRQ-------VGLLP---
MLBr_00815|M.leprae_Br4923 YWLDTNRPISKSDAVEGTVQFAWGG------LSHVPLTRL
: ::