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PRPRIHSVEDLLDATERIAVQDGPAAVTVRAVSQATGISNGAIYHAFGSRGGMVGHAWLRAAQRFLDMQR DAVDGALAESETRTAAVNAVVAAADTPAAFAERFPESSRLVLSVRREDVLGSGIPEEVARDMAAVDALLV RLFIRLSMALWGRRDGRAVQVIEDCIVGLPTGLLLRGRRPPDTATRSRLEAAVRAVLALNPPPANPKT*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_2466c | - | - | 100% (209) | putative transcriptional regulator, TetR |
| M. abscessus ATCC 19977 | MAB_3395 | - | 2e-19 | 32.31% (195) | putative transcriptional regulator, TetR |
| M. abscessus ATCC 19977 | MAB_4625 | - | 2e-10 | 23.92% (209) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0310 | - | 9e-07 | 40.68% (59) | TetR/ACRR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_4881 | - | 2e-14 | 26.47% (204) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0302 | - | 9e-07 | 40.68% (59) | TetR/ACRR family transcriptional regulator |
| M. leprae Br4923 | MLBr_02497 | - | 1e-36 | 48.41% (157) | hypothetical protein MLBr_02497 |
| M. marinum M | MMAR_3161 | - | 3e-05 | 31.34% (67) | transcriptional regulatory protein |
| M. avium 104 | MAV_1113 | - | 8e-53 | 51.50% (200) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_6556 | - | 2e-42 | 45.10% (204) | putative transcriptional regulator |
| M. thermoresistible (build 8) | TH_2855 | - | 7e-05 | 28.41% (88) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_2593 | - | 5e-05 | 34.85% (66) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_5831 | - | 5e-57 | 54.90% (204) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MAB_2466c|M.abscessus_ATCC_199 ----------------------------------------MPRPRIHSVE
MLBr_02497|M.leprae_Br4923 --------------------------------------------------
MAV_1113|M.avium_104 ---------------------------------------------MLDFD
Mvan_5831|M.vanbaalenii_PYR-1 -------------------------MGPAITERALCYRCPVPRPRVIDLD
MSMEG_6556|M.smegmatis_MC2_155 ----------------------------------------MPRPRMHDPQ
Mb0310|M.bovis_AF2122/97 ---------------------------------MGVPAKKKQQQGERSRE
Rv0302|M.tuberculosis_H37Rv ---------------------------------MGVPAKKKQQQGERSRE
Mflv_4881|M.gilvum_PYR-GCK ----------------------------------------MPRPARYTVD
TH_2855|M.thermoresistible__bu -------LSQSPDNATSSSRAGSGAGSGAGSGAEPIGRDTPRRRPRIRPE
MUL_2593|M.ulcerans_Agy99 MPRLRCGKGGLRDGGGGSTVIDTNSFAKRDIVGPVKRVPYAEASRVLLRD
MMAR_3161|M.marinum_M ----------------------------------MRWGAAAPSDRDSARD
MAB_2466c|M.abscessus_ATCC_199 DLLDATERIAVQDGPAAVTVRAVSQATGISNGAIYHAFGSRGGMVGHAWL
MLBr_02497|M.leprae_Br4923 ------------------------------------MFASRAALLGRVWL
MAV_1113|M.avium_104 HLMDVAEQLAAESGPPAITIRALSEATAISNGAIYHAFGSRGGLLGHVWL
Mvan_5831|M.vanbaalenii_PYR-1 HLMDAVEQLAADAGPRAVTIRALSQRTAISNGAIYHAFGSRGGLLGQVWL
MSMEG_6556|M.smegmatis_MC2_155 AILDVAESLAVRCGPAAVTIRAVGDAVGVSNGALYHEFGSRSGLLTRAWL
Mb0310|M.bovis_AF2122/97 SILDATERLMATKGYAATSISDIRDACGLAPSSIYWHFGSKEGVLAAMME
Rv0302|M.tuberculosis_H37Rv SILDATERLMATKGYAATSISDIRDACGLAPSSIYWHFGSKEGVLAAMME
Mflv_4881|M.gilvum_PYR-GCK VLLDAAAELLAAEGPAAVTMSAVARSTGAPSGSVYHRFPTRAALCGELWV
TH_2855|M.thermoresistible__bu EIVSAAAEFFAREGYANVGMRDVAEAVGIRGASLYHHFGSKEEILYAICL
MUL_2593|M.ulcerans_Agy99 SVLDAMRDLLFTRDWSAITLSDVARSAGISRQTIYNEFGSRQGLAQGYAL
MMAR_3161|M.marinum_M RLLDAAERCLESCGVVGTTMEDIGRTAGVSRATVYRYFPNREAVMSGVII
* .: :
MAB_2466c|M.abscessus_ATCC_199 RAAQRFLDMQRDAVDGALAESETRTAAVNAVVAAADTPAAFAERFPESSR
MLBr_02497|M.leprae_Br4923 RAGYRFLKTQTALVDQALSASVRR-AGVEAVVAAADAPVVFAEQYPDSSR
MAV_1113|M.avium_104 RAGKRYLSFQRAAVAKALSRGVSGEAAVDAVVAAAECPATFSHEHPASAR
Mvan_5831|M.vanbaalenii_PYR-1 RAARRFLSEQRSAVARALADGVTPETAVEAVVAAAQCPATFLDGHPATAM
MSMEG_6556|M.smegmatis_MC2_155 RAVHRLQTVLTELVETAEPG-------AAAIAAAAEASIVLAERHPSSAA
Mb0310|M.bovis_AF2122/97 RGAQRFFAAIPTWDEAHGPVE-------QRSERQLTELVSLQSQHPDFLR
Rv0302|M.tuberculosis_H37Rv RGAQRFFAAIPTWDEAHGPVE-------QRSERQLTELVSLQSQHPDFLR
Mflv_4881|M.gilvum_PYR-GCK RTEERFQEELLEALSGDGDPQ-------NRCVAGALRNMQWCRENPVEAH
TH_2855|M.thermoresistible__bu TVTKEPNELNLPLLDAAGTP---------AERLSALIRAHLEHLIRRRVE
MUL_2593|M.ulcerans_Agy99 RLADRLVDKVHAALDANVGN------------IYEAFLQGFRSFFGESAA
MMAR_3161|M.marinum_M RAAERYLDRINPRIAEHTDLG---------SALVDFVEYTVEAARREEII
.
MAB_2466c|M.abscessus_ATCC_199 LVLSVRREDVLGS-GIPEEVARDMAAVDALLVRLFIRLSMALWGRRDGRA
MLBr_02497|M.leprae_Br4923 LLLTVRREELLKS-FLPNEIEIELRELDALLISLLTRLAVVIWDRKDTGA
MAV_1113|M.avium_104 FLLRVRRDELLGAADVPAELADELRRLDDDLAHLFIELAEKVWGRRDQQA
Mvan_5831|M.vanbaalenii_PYR-1 YLLALPRNELLGARDVSDELADDLRGLDGELAGLFIELAEHMWRRRDRHA
MSMEG_6556|M.smegmatis_MC2_155 LVLQTRRDELIGA-----DPPAEVKDAQNRLVDLMIQLADDAWGRRDGAA
Mb0310|M.bovis_AF2122/97 LFYLLSMERSQDPVVAAVVRRVRNTAIARFRDSITHLLPSDIPPGKADLV
Rv0302|M.tuberculosis_H37Rv LFYLLSMERSQDPAVAAVVRRVRNTAIARFRDSITHLLPSDIPPGKADLV
Mflv_4881|M.gilvum_PYR-GCK VLLAGP--DQLDMGEWPDTVAGRRKRLQRKLRKVLAEIAGDH-GRIDGRV
TH_2855|M.thermoresistible__bu HLVALHDINSLTPEHRAIIDDLRRYYQRRVRDVIVAGVRSGEFDVPDPKL
MUL_2593|M.ulcerans_Agy99 DPLVISLLTGVAKPDLLQLITTDSAPIITRASARLATAFTQTWVATSDDD
MMAR_3161|M.marinum_M GLLFGSDEELAGVGLAAGTSTSLFELVTEFLRPIFRRHWSYVEPGVSVDD
MAB_2466c|M.abscessus_ATCC_199 VQVIEDCIVGLPTGLLLR--GRRPPDTATRSRLEAAVRAVLALNPPPANP
MLBr_02497|M.leprae_Br4923 IDTITTCLMDLPTAVLLH--RDRLGNKTARKHLHAAVRAVLEVGPPP---
MAV_1113|M.avium_104 VGAIRTCVVELPTALLID--AHALHDAAALQRLAAAVRAVLALTPPTTST
Mvan_5831|M.vanbaalenii_PYR-1 VAAIRACVVDLPTALLLR--GQHPPDPAARDRLTAAVRAVLALTPPTSRN
MSMEG_6556|M.smegmatis_MC2_155 VDTVTTCIVDLPTAILLH--RNRIADPTARRQLRAAVAAVLEVGPAPRAQ
Mb0310|M.bovis_AF2122/97 VAELTAFAVALSDGVYFA--GHLEPDTTDVERMYRRLRQALEALIPVLLE
Rv0302|M.tuberculosis_H37Rv VAELTAFAVALSDGVYFA--GHLEPDTTDVERMYRRLRQALEALIPVLLE
Mflv_4881|M.gilvum_PYR-GCK DGRVAAAVMDVPAAIVRR--HLRARQSIPAAADDIVADCARALICPN---
TH_2855|M.thermoresistible__bu AALLILDALNGVSGWFHPDRGHSLPDVIAAYTEMIVERVLRARIS-----
MUL_2593|M.ulcerans_Agy99 ANVLARAIVRLSLSYVSMPPEADHNVAADLARLMTPFAERHGVINVP---
MMAR_3161|M.marinum_M AAEWVLRTILSLLTVRGPRERSRDGLRTFLSRFLLPAILASDHCRPM---
:
MAB_2466c|M.abscessus_ATCC_199 KT------------
MLBr_02497|M.leprae_Br4923 --------------
MAV_1113|M.avium_104 KPKPRTTLTKGAPR
Mvan_5831|M.vanbaalenii_PYR-1 TPAH----------
MSMEG_6556|M.smegmatis_MC2_155 RHRAQEAS------
Mb0310|M.bovis_AF2122/97 ET------------
Rv0302|M.tuberculosis_H37Rv ET------------
Mflv_4881|M.gilvum_PYR-GCK --------------
TH_2855|M.thermoresistible__bu --------------
MUL_2593|M.ulcerans_Agy99 --------------
MMAR_3161|M.marinum_M --------------