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PRPARYTVDVLLDAAAELLAAEGPAAVTMSAVARSTGAPSGSVYHRFPTRAALCGELWVRTEERFQEELL EALSGDGDPQNRCVAGALRNMQWCRENPVEAHVLLAGPDQLDMGEWPDTVAGRRKRLQRKLRKVLAEIAG DHGRIDGRVDGRVAAAVMDVPAAIVRRHLRARQSIPAAADDIVADCARALICPN*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_4881 | - | - | 100% (195) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_2228 | - | 1e-09 | 26.42% (193) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_5272 | - | 3e-07 | 35.78% (109) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3081 | - | 1e-07 | 29.41% (153) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv3055 | - | 1e-07 | 29.41% (153) | TetR family transcriptional regulator |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4625 | - | 8e-27 | 37.17% (191) | TetR family transcriptional regulator |
| M. marinum M | MMAR_1145 | - | 4e-08 | 26.32% (95) | transcriptional regulatory protein |
| M. avium 104 | MAV_4715 | - | 6e-20 | 35.98% (189) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_0859 | - | 2e-20 | 36.42% (173) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_2228 | - | 3e-10 | 34.91% (106) | PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN |
| M. ulcerans Agy99 | MUL_4876 | - | 6e-08 | 26.09% (184) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_1548 | - | 1e-80 | 75.38% (195) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4881|M.gilvum_PYR-GCK --------------------MPRPARYTVDVLLDAAAELLAAEGPAAVTM
Mvan_1548|M.vanbaalenii_PYR-1 --------------------MPRPARYTTDVLLDAAAELLAAEGPAAVTM
MAV_4715|M.avium_104 ------------------------------MILDAARALVLDGGPRTASV
MSMEG_0859|M.smegmatis_MC2_155 --------------------MAPPRKHETDAILDAARALVLTEGPRAAGV
MAB_4625|M.abscessus_ATCC_1997 --------------------MGRKPQYSADDILDAALGLVAAGGPSAATA
Mb3081|M.bovis_AF2122/97 MSGAERLGDLPVFARQEPVPERGDAARNRALLLEAARRLIARSGADAITM
Rv3055|M.tuberculosis_H37Rv MSGAERLGDLPVFARQEPVPERGDAARNRALLLEAARRLIARSGADAITM
TH_2228|M.thermoresistible__bu --------------MTGNWLADRRTEVAAERILDAAHELFTRHDAATVGM
MMAR_1145|M.marinum_M --------------MAATRTTARAGGDRRAAIIEAALNRFLSQGIDATAL
MUL_4876|M.ulcerans_Agy99 -----MTVPTFSTRSQLGRPVGARGEQTRQRIITAAMRCVAEAGPAQASI
:: ** . .
Mflv_4881|M.gilvum_PYR-GCK SAVARSTGAPSGSVYHRFPTRAALCGELWVRTEERFQEELLEALSGDGDP
Mvan_1548|M.vanbaalenii_PYR-1 SAVARSTGAPSGSVYHRFPTRAALCGELWVRTEERFQGELIEALSVDGDA
MAV_4715|M.avium_104 AAIATASGAPAGTLYHRFGNRDGILTAAWLRALERFQARALAADG-DTPE
MSMEG_0859|M.smegmatis_MC2_155 AAIAKASGAPVGTLYHRFGNRDGILKATWLRGIERFQRRAMAADG-ATPV
MAB_4625|M.abscessus_ATCC_1997 TAIGRVLGAPSGSIYHRFPSRDELMARLWLRSIARYQDGVLTALA-LPDA
Mb3081|M.bovis_AF2122/97 DDVAAAAGVGKGTLFRRFGSRAGLMMVLLDEDERASQQAFLFGPPPLGPD
Rv3055|M.tuberculosis_H37Rv DDVAAAAGVGKGTLFRRFGSRAGLMMVLLDEDERASQQAFLFGPPPLGPD
TH_2228|M.thermoresistible__bu RDIARAAGCSRATLYRYFDSREALHTAYVHREARRLYRELGPRLAAIGDP
MMAR_1145|M.marinum_M RQIQRDAGVSNGSFFHHFPSKEVLAAAVYVDCVTRYQQALLKDLARYPDA
MUL_4876|M.ulcerans_Agy99 REIAKAADMTSGSLYHYFPNKSELLNATATEIEEIVLPRLHAAAASSDDI
: . .:.:: * .: :
Mflv_4881|M.gilvum_PYR-GCK QNRCVAGALRNMQWCRENPVEAHVLLAGPDQLDMGEWPDT-VAGRRKRLQ
Mvan_1548|M.vanbaalenii_PYR-1 QQRCVSGALRIVQWCRDNPVEAQVMLAGPTELGMGDWPEP-VTSRRKRLQ
MAV_4715|M.avium_104 DTAVAMAV-AAVSFARALPDDARLLLTIRPGDLLDGEPDAAFRQTLAAMN
MSMEG_0859|M.smegmatis_MC2_155 DVAVAMAG-AVLQFARDEPEDARLLLSIRRADLLDGGPDADFDATLADMN
MAB_4625|M.abscessus_ATCC_1997 DDALAAAIDHAFDWTASNHNEALLLLQYEKADLVAHWPDT-LATELKSLN
Mb3081|M.bovis_AF2122/97 APPLDRLIAFGRERMRFVHAHHQLLSEANRD------PQTRHSAALSVLR
Rv3055|M.tuberculosis_H37Rv APPLDRLIAFGRERMRFVHAHHQLLSEANRD------PQTRHSAALSVLR
TH_2228|M.thermoresistible__bu QNRLIEGILAALDAVRENPALSSWFAAGHRP----------VGAELADRS
MMAR_1145|M.marinum_M ESAVRGIVGMHLSWCTEHPEMARFLITMTEP-AVHRAAADELRSHNERFA
MUL_4876|M.ulcerans_Agy99 VDRLDAVLDESKRLMRDYPYLAGFLRAVRAENADQTGGGRRTYPGSKALR
:
Mflv_4881|M.gilvum_PYR-GCK RKLRKVLAEIAG-DHGRIDGRVDGRVAAAVMDVPAAIVRRHLRARQSIPA
Mvan_1548|M.vanbaalenii_PYR-1 RKLRKALSDLSD-DTARVN--------AAIVDVPAAIVRRHLRAGQTIPA
MAV_4715|M.avium_104 APLTQRLAQLARHLYGNARPRSVDAVARAVADLPYAVVRRHAHDDPMPS-
MSMEG_0859|M.smegmatis_MC2_155 APVFERLHELARGIFGRDDDRAMDAVMRAVADLPYATVRRHIDDGKWPV-
MAB_4625|M.abscessus_ATCC_1997 SRVRKTLREYTDRRYGKVTTERIDKVMFALIDMPYAAVRRHLPDKGEPAP
Mb3081|M.bovis_AF2122/97 THLRVLLASAPT----TGDLDAQTDALLALLDVDY--VEHQLNAGGHTLQ
Rv3055|M.tuberculosis_H37Rv THLRVLLASAPT----TGDLDAQTDALLALLDVDY--VEHQLNAGGHTLQ
TH_2228|M.thermoresistible__bu EVIHGLVAGFLRSQGFDDDGRRARWLVRVIVSLLLFPGRDEAEERALLED
MMAR_1145|M.marinum_M TAVQTWWRPHAHYGALRPLSPAHSQALWLGPAQELVRAWLLGNLAAPPNA
MUL_4876|M.ulcerans_Agy99 DVITEIVDDARG-RGVLSAGIAPGAAVDAICALTRGLTEQAANLGPQSYD
:
Mflv_4881|M.gilvum_PYR-GCK AADDIVADCARALICPN---------------------------------
Mvan_1548|M.vanbaalenii_PYR-1 VADAIVEECARALIAPS---------------------------------
MAV_4715|M.avium_104 WLETDVAASARAVLRS----------------------------------
MSMEG_0859|M.smegmatis_MC2_155 WLSEDLATSVRRLLSVDKIVSASREIAAPSDVIFELIADPAQQPRWDGNE
MAB_4625|M.abscessus_ATCC_1997 WLREFVHTSAHALLAR----------------------------------
Mb3081|M.bovis_AF2122/97 TLGDAWESLARKLCGR----------------------------------
Rv3055|M.tuberculosis_H37Rv TLGDAWESLARKLCGR----------------------------------
TH_2228|M.thermoresistible__bu FVVPAVAQATE---------------------------------------
MMAR_1145|M.marinum_M ADAAILADAAWLCLRAGPAG------------------------------
MUL_4876|M.ulcerans_Agy99 VTLDSAKQLLRGSLFAGAKPTATRRT------------------------
Mflv_4881|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1548|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_4715|M.avium_104 -----------------------------------------------FGE
MSMEG_0859|M.smegmatis_MC2_155 NLLRMASGGRVRGVGEVFTMEIKQGGFRDNHVIEFEEGRRIAWRPAVAGE
MAB_4625|M.abscessus_ATCC_1997 ----------------------------------------------ACLN
Mb3081|M.bovis_AF2122/97 --------------------------------------------------
Rv3055|M.tuberculosis_H37Rv --------------------------------------------------
TH_2228|M.thermoresistible__bu --------------------------------------------------
MMAR_1145|M.marinum_M --------------------------------------------------
MUL_4876|M.ulcerans_Agy99 --------------------------------------------------
Mflv_4881|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1548|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_4715|M.avium_104 RP------------------------------------------------
MSMEG_0859|M.smegmatis_MC2_155 QPLGHLWRWELQPAGEGRTLVTHTYDWTQLTDEKRFPKASATTADKLQES
MAB_4625|M.abscessus_ATCC_1997 EP------------------------------------------------
Mb3081|M.bovis_AF2122/97 --------------------------------------------------
Rv3055|M.tuberculosis_H37Rv --------------------------------------------------
TH_2228|M.thermoresistible__bu --------------------------------------------------
MMAR_1145|M.marinum_M --------------------------------------------------
MUL_4876|M.ulcerans_Agy99 --------------------------------------------------
Mflv_4881|M.gilvum_PYR-GCK ----------
Mvan_1548|M.vanbaalenii_PYR-1 ----------
MAV_4715|M.avium_104 ----------
MSMEG_0859|M.smegmatis_MC2_155 VDRLAAIVEG
MAB_4625|M.abscessus_ATCC_1997 ----------
Mb3081|M.bovis_AF2122/97 ----------
Rv3055|M.tuberculosis_H37Rv ----------
TH_2228|M.thermoresistible__bu ----------
MMAR_1145|M.marinum_M ----------
MUL_4876|M.ulcerans_Agy99 ----------