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PRLRCGKGGLRDGGGGSTVIDTNSFAKRDIVGPVKRVPYAEASRVLLRDSVLDAMRDLLFTRDWSAITLS DVARSAGISRQTIYNEFGSRQGLAQGYALRLADRLVDKVHAALDANVGNIYEAFLQGFRSFFGESAADPL VISLLTGVAKPDLLQLITTDSAPIITRASARLATAFTQTWVATSDDDANVLARAIVRLSLSYVSMPPEAD HNVAADLARLMTPFAERHGVINVP*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_2593 | - | - | 100% (235) | TetR family transcriptional regulator |
| M. ulcerans Agy99 | MUL_2746 | - | 4e-39 | 42.93% (191) | TetR family transcriptional regulator |
| M. ulcerans Agy99 | MUL_4487 | - | 7e-07 | 26.94% (193) | transcriptional regulatory protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3277c | - | 1e-102 | 91.67% (204) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_4718 | - | 2e-84 | 73.81% (210) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv3249c | - | 1e-102 | 91.67% (204) | TetR family transcriptional regulator |
| M. leprae Br4923 | MLBr_00064 | - | 3e-05 | 35.71% (70) | putative transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_3596c | - | 4e-71 | 65.33% (199) | TetR family transcriptional regulator |
| M. marinum M | MMAR_1294 | - | 1e-117 | 99.54% (216) | TetR family transcriptional regulator |
| M. avium 104 | MAV_4212 | - | 8e-94 | 86.00% (200) | putative transcriptional regulatory protein |
| M. smegmatis MC2 155 | MSMEG_1842 | - | 4e-85 | 70.04% (227) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_0467 | - | 2e-85 | 80.71% (197) | POSSIBLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY |
| M. vanbaalenii PYR-1 | Mvan_1745 | - | 1e-85 | 77.27% (198) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MUL_2593|M.ulcerans_Agy99 ---------------MPRLRCGKGGLRDGGGGSTVIDTNSFAKRDIVGPV
MMAR_1294|M.marinum_M ----------------------------------MIDTNSFAKRDIVGPV
Mb3277c|M.bovis_AF2122/97 -----------------------------------MSTPSAT----VAPV
Rv3249c|M.tuberculosis_H37Rv -----------------------------------MSTPSAT----VAPV
MAV_4212|M.avium_104 -------------------------------------------------M
Mflv_4718|M.gilvum_PYR-GCK -MTAQPIATSARVATRHADQRRADTRARGASLGPVRATVIVAPVGG-GND
Mvan_1745|M.vanbaalenii_PYR-1 -MRATHRAEPC----RHARSRNTASQGTAVTASAGPGTITVARVGL-SND
TH_0467|M.thermoresistible__bu ---------------------------------------VVSRR-----D
MSMEG_1842|M.smegmatis_MC2_155 MIHAVTHAVAG---------AQFGAPARVVRGPLTAESDIVARVSRPRAK
MAB_3596c|M.abscessus_ATCC_199 -MTDVLP--------------GRDALTSASVPARLPGVTRPDALRAGGSS
MLBr_00064|M.leprae_Br4923 --------------------------------------MINSTAGQTSQS
MUL_2593|M.ulcerans_Agy99 KRVPYAEASRVLLRDSVLDAMRDLLFTRDWSAITLSDVARSAGISRQTIY
MMAR_1294|M.marinum_M KRVPYAEASRVLLRDSVLDAMRDLLLTRDWSAITLSDVARSAGISRQTIY
Mb3277c|M.bovis_AF2122/97 KRIPYAEASRALLRDSVLDAMRDLLLTRDWSAITLSDVARAAGISRQTIY
Rv3249c|M.tuberculosis_H37Rv KRIPYAEASRALLRDSVLDAMRDLLLTRDWSAITLSDVARAAGISRQTIY
MAV_4212|M.avium_104 KRMPYAEASRALLRDSVLDAMRDLLVTRDWSAITLSDVARAAGISRQTIY
Mflv_4718|M.gilvum_PYR-GCK KRISYAEASRVLLRDSILDGMREMLLARDWSQITLSDVAKAAGISRQTIY
Mvan_1745|M.vanbaalenii_PYR-1 KRVSYAEASRVLLRDSILDGMREMLLTRDWSAITLSDVAKAAGISRQTIY
TH_0467|M.thermoresistible__bu KRVPYAEASRVLLRDSILDGMRELLQTRDWSQITLADVAKAAGISRQTIY
MSMEG_1842|M.smegmatis_MC2_155 QRMPYAEASRVLLRDSILDGMRDLLLTRDWSAITLSHVAQAAGVSRQTIY
MAB_3596c|M.abscessus_ATCC_199 HRVPYAEAARALLRESVLDALGDLLRQRDWSAVTMSDVSRRAGVSRQTLY
MLBr_00064|M.leprae_Br4923 RSRRSTRPSGDDRELAILATAEQLLEDRPLTEISVDYLAKSAGISRPTFY
: :..: . ::* ::* * : ::: ::: **:** *:*
MUL_2593|M.ulcerans_Agy99 NEFGSRQGLAQGYALRLADRLVDKVHAALDANVGNIYEAFLQGFRSFFGE
MMAR_1294|M.marinum_M NEFGSRQGLAQGYALRLADRLVDKVHAALDANVGNIYEAFLQGFRSFFGE
Mb3277c|M.bovis_AF2122/97 NEFGSRQGLAQGYALRLADRLVDNVHASLDANVGNFYEAFLQGFRSFFAE
Rv3249c|M.tuberculosis_H37Rv NEFGSRQGLAQGYALRLADRLVDNVHASLDANVGNFYEAFLQGFRSFFAE
MAV_4212|M.avium_104 NEFGSRQGLAQGYALRLADRLVDTIHEALDAHVGNIYESFLDAFRRFFAD
Mflv_4718|M.gilvum_PYR-GCK NEFGSRQGLAQGYAMRLADRLVDQIHAAIDNNVGDMYAAFLQGFRDFFVE
Mvan_1745|M.vanbaalenii_PYR-1 NEFGSRQGLAQGYAMRLADRLVDQIHGAINGNAGDVYAAFLQGFRDFFVE
TH_0467|M.thermoresistible__bu NEFGSRQGLAQGYALRLADRLVDEVDEAIANNVGDIHAAFLAGFRKFFAE
MSMEG_1842|M.smegmatis_MC2_155 NEFGSRQGLAEGYAMRLADRLVDAVDDAINNNVGDVYAAFLEGFRAFFAE
MAB_3596c|M.abscessus_ATCC_199 NEFGSRQGLAQGYALRLAHRLVDAVGDAIYAHVGDIHGALHSGFADFFAE
MLBr_00064|M.leprae_Br4923 FYFASKEAVLLTLLDRVFNKANAALETLIKNRDNKRGNKWRTGINVFFET
*.*::.: *: .: : : . .. .: **
MUL_2593|M.ulcerans_Agy99 SAADPLVISLLTGVAKPDLLQLITTDSAPIITRASARLATAFTQTWVATS
MMAR_1294|M.marinum_M SAADPLVISLLTGVAKPDLLQLITTDSAPIITRASARLATAFTQTWVATS
Mb3277c|M.bovis_AF2122/97 SAADPLVISLLTGVAKPDLLQLITTDSAPIITRASARLAPAFTDTWVATT
Rv3249c|M.tuberculosis_H37Rv SAADPLVISLLTGVAKPDLLQLITTDSAPIITRASARLAPAFTDTWVATT
MAV_4212|M.avium_104 AAADPLVTSLRTGVAKPDLLQLITTDSAVIITRASARLASALTHTWVSTT
Mflv_4718|M.gilvum_PYR-GCK SAADPLVISLLTGSSKPDLLQLITTDSAPIINHCSSRLTESLMGSWVRCS
Mvan_1745|M.vanbaalenii_PYR-1 SAADPLVISLLTGTSKPDLLQLITTDSAPIINHCSSRLTESFMSSWVRVS
TH_0467|M.thermoresistible__bu SAADPLVISLLTGSAKPDLLQLITTDSAPIITRASQRLTESFQSSWVRAS
MSMEG_1842|M.smegmatis_MC2_155 SAADPLVISLLTGAAKPDLLQIITIGSGPIITRCSERLTATFQSSWIKAS
MAB_3596c|M.abscessus_ATCC_199 SAADPMVISLLTGEAKPELMRIVTVDSALIVVPASARLTESFMNSWVAAS
MLBr_00064|M.leprae_Br4923 FGSHKAVTCAGQVTRDNTEVRKLWSTFMQKWISYTAAVIDAERKRGVAPD
.:. * . . :: : : : : :
MUL_2593|M.ulcerans_Agy99 DDDANVLARAIVRLSLSYVSMPPEADHNVAADLARLMTPFAERHGVINVP
MMAR_1294|M.marinum_M DDDANVLARAIVRLSLSYVSMPPEADHNVAADLARLMTPFAERHGVINVP
Mb3277c|M.bovis_AF2122/97 DNDANVLSRAIVRLCLSYVSMPPEADHDVAADLARLITPFAERHGVINVP
Rv3249c|M.tuberculosis_H37Rv DNDANVLSRAIVRLCLSYVSMPPEADHDVAADLARLITPFAERHGVINVP
MAV_4212|M.avium_104 DEDAGVLARAIVRLALSYVSMPPEADHDVAADLARLMTPFAERHGVVNVG
Mflv_4718|M.gilvum_PYR-GCK EEDAGVLSRAIVRLAMSYISMPPEADHDVARDLARLMTPFAERYGVVADP
Mvan_1745|M.vanbaalenii_PYR-1 QEDAGVLARAIVRLAMSYISMPPEADHDVARDLARLMTPFAERYGVIDP-
TH_0467|M.thermoresistible__bu EEDAGVLARAIVRLAMSYVSMPPEADHDVAHDLARLMTPFAERYGVIEEV
MSMEG_1842|M.smegmatis_MC2_155 DDDAGVLARAIVRLAMSYVSMPPEADHDVAGDLARLMSPFAERYGVIDTP
MAB_3596c|M.abscessus_ATCC_199 QEDASILARSIVRLAISYVSMPPESDHDVALDMARLLSPFVETNALADKA
MLBr_00064|M.leprae_Br4923 TLPATELATALNLMNERALFASFTAEQPHVPESRVLDTLVHIWVSSIYNE
* *: :: : : . ::: . : * : . .
MUL_2593|M.ulcerans_Agy99 ------------
MMAR_1294|M.marinum_M ------------
Mb3277c|M.bovis_AF2122/97 ------------
Rv3249c|M.tuberculosis_H37Rv ------------
MAV_4212|M.avium_104 ------------
Mflv_4718|M.gilvum_PYR-GCK VEGGNSQVTRRP
Mvan_1745|M.vanbaalenii_PYR-1 ------------
TH_0467|M.thermoresistible__bu ------------
MSMEG_1842|M.smegmatis_MC2_155 ------------
MAB_3596c|M.abscessus_ATCC_199 ------------
MLBr_00064|M.leprae_Br4923 IR----------