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MPRPRMHDPQAILDVAESLAVRCGPAAVTIRAVGDAVGVSNGALYHEFGSRSGLLTRAWLRAVHRLQTVL TELVETAEPGAAAIAAAAEASIVLAERHPSSAALVLQTRRDELIGADPPAEVKDAQNRLVDLMIQLADDA WGRRDGAAVDTVTTCIVDLPTAILLHRNRIADPTARRQLRAAVAAVLEVGPAPRAQRHRAQEAS
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_6556 | - | - | 100% (204) | putative transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_0859 | - | 1e-20 | 35.58% (163) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_4022 | - | 2e-09 | 37.08% (89) | TetR-family protein transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0310 | - | 4e-05 | 24.74% (190) | TetR/ACRR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_4881 | - | 5e-15 | 31.09% (193) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv1255c | - | 3e-06 | 25.00% (188) | transcriptional regulatory protein |
| M. leprae Br4923 | MLBr_02497 | - | 2e-33 | 46.15% (156) | hypothetical protein MLBr_02497 |
| M. abscessus ATCC 19977 | MAB_2466c | - | 2e-42 | 45.10% (204) | putative transcriptional regulator, TetR |
| M. marinum M | MMAR_0237 | - | 5e-06 | 24.00% (150) | TetR family transcriptional regulator |
| M. avium 104 | MAV_1113 | - | 6e-40 | 46.35% (192) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_2336 | - | 6e-06 | 31.30% (115) | transcriptional regulator, TetR family protein |
| M. ulcerans Agy99 | MUL_4876 | - | 3e-06 | 24.00% (150) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_5831 | - | 2e-36 | 42.36% (203) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_0237|M.marinum_M ------------------MGARGEQTRQRIITAAMRCVAEAGPAQASIRE
MUL_4876|M.ulcerans_Agy99 ---MTVPTFSTRSQLGRPVGARGEQTRQRIITAAMRCVAEAGPAQASIRE
MLBr_02497|M.leprae_Br4923 --------------------------------------------------
MAB_2466c|M.abscessus_ATCC_199 ------------------MPRPRIHSVEDLLDATERIAVQDGPAAVTVRA
MAV_1113|M.avium_104 -----------------------MLDFDHLMDVAEQLAAESGPPAITIRA
Mvan_5831|M.vanbaalenii_PYR-1 ---MGPAITERALCYRCPVPRPRVIDLDHLMDAVEQLAADAGPRAVTIRA
MSMEG_6556|M.smegmatis_MC2_155 ------------------MPRPRMHDPQAILDVAESLAVRCGPAAVTIRA
Mflv_4881|M.gilvum_PYR-GCK ------------------MPRPARYTVDVLLDAAAELLAAEGPAAVTMSA
Rv1255c|M.tuberculosis_H37Rv -----------MAGTDWLSARRTELAADRILDAAERLFTQRDPASIGMNE
Mb0310|M.bovis_AF2122/97 -----------MGVPAKKKQQQGERSRESILDATERLMATKGYAATSISD
TH_2336|M.thermoresistible__bu VSGVGKPISREAALLTSRASAGTGPTRQRLIEVAIELFKQHSVAGTSLQM
MMAR_0237|M.marinum_M IAKAADMTSGSLYHYFPNKSELLNATATEIEEIVLPRLHAAAASSDDI--
MUL_4876|M.ulcerans_Agy99 IAKAADMTSGSLYHYFPNKSELLNATATEIEEIVLPRLHAAAASSDDI--
MLBr_02497|M.leprae_Br4923 --------------MFASRAALLGRVWLRAGYRFLKTQTALVDQALSASV
MAB_2466c|M.abscessus_ATCC_199 VSQATGISNGAIYHAFGSRGGMVGHAWLRAAQRFLDMQRDAVDGALAESE
MAV_1113|M.avium_104 LSEATAISNGAIYHAFGSRGGLLGHVWLRAGKRYLSFQRAAVAKALSRGV
Mvan_5831|M.vanbaalenii_PYR-1 LSQRTAISNGAIYHAFGSRGGLLGQVWLRAARRFLSEQRSAVARALADGV
MSMEG_6556|M.smegmatis_MC2_155 VGDAVGVSNGALYHEFGSRSGLLTRAWLRAVHRLQTVLTELVETAEPG--
Mflv_4881|M.gilvum_PYR-GCK VARSTGAPSGSVYHRFPTRAALCGELWVRTEERFQEELLEALSGDGDP--
Rv1255c|M.tuberculosis_H37Rv IAKAAGCSRATLYRYFDSREALRTAYVHRETRRLGREIMVKIADVVEP--
Mb0310|M.bovis_AF2122/97 IRDACGLAPSSIYWHFGSKEGVLAAMMERGAQRFFAAIPTWDEAHGPVE-
TH_2336|M.thermoresistible__bu ISDALGLTKSAIYHHFRTRDELLTAVMEPLISEVAEIVSAAEARRGAR--
* .: :
MMAR_0237|M.marinum_M -----VDRLDAVLDESKRLMRDYPYLAGFLRAVRAENADQTGGGRRTYPG
MUL_4876|M.ulcerans_Agy99 -----VDRLDAVLDESKRLMRDYPYLAGFLRAVRAENADQTGGGRRTYPG
MLBr_02497|M.leprae_Br4923 RR-AGVEAVVAAADAPVVFAEQYPDSSRLLLTVRRE--ELLKS-FLPNEI
MAB_2466c|M.abscessus_ATCC_199 TRTAAVNAVVAAADTPAAFAERFPESSRLVLSVRRE--DVLGS-GIPEEV
MAV_1113|M.avium_104 SGEAAVDAVVAAAECPATFSHEHPASARFLLRVRRD--ELLGAADVPAEL
Mvan_5831|M.vanbaalenii_PYR-1 TPETAVEAVVAAAQCPATFLDGHPATAMYLLALPRN--ELLGARDVSDEL
MSMEG_6556|M.smegmatis_MC2_155 -----AAAIAAAAEASIVLAERHPSSAALVLQTRRD--ELIGA-----DP
Mflv_4881|M.gilvum_PYR-GCK -----QNRCVAGALRNMQWCRENPVEAHVLLAGPDQ----LDMGEWPDTV
Rv1255c|M.tuberculosis_H37Rv -----AERLLVSITTTLRMVRDNPALAAWFTTTRPP-------------I
Mb0310|M.bovis_AF2122/97 ------QRSERQLTELVSLQSQHPDFLRLFYLLSME--RSQDPVVAAVVR
TH_2336|M.thermoresistible__bu ------TRADHFLRGYAALAAAHREVISLLTGDPGV-----------VAL
.
MMAR_0237|M.marinum_M SKALRDVITEIVDDARGRGVLSAGIAPGAAVDAICALTRGLTEQAANLGP
MUL_4876|M.ulcerans_Agy99 SKALRDVITEIVDDARGRGVLSAGIAPGAAVDAICALTRGLTEQAANLGP
MLBr_02497|M.leprae_Br4923 EIELRELDALLISLLTRLAVVIWDRKDTGAIDTITTCLMDLPTAVLLHRD
MAB_2466c|M.abscessus_ATCC_199 ARDMAAVDALLVRLFIRLSMALWGRRDGRAVQVIEDCIVGLPTGLLLRGR
MAV_1113|M.avium_104 ADELRRLDDDLAHLFIELAEKVWGRRDQQAVGAIRTCVVELPTALLIDAH
Mvan_5831|M.vanbaalenii_PYR-1 ADDLRGLDGELAGLFIELAEHMWRRRDRHAVAAIRACVVDLPTALLLRGQ
MSMEG_6556|M.smegmatis_MC2_155 PAEVKDAQNRLVDLMIQLADDAWGRRDGAAVDTVTTCIVDLPTAILLHRN
Mflv_4881|M.gilvum_PYR-GCK AGRRKRLQRKLRKVLAEIAG-DHGRIDGRVDGRVAAAVMDVPAAIVRRHL
Rv1255c|M.tuberculosis_H37Rv GGEMAGRSEVIAALAAAFLN-SLGPDDPTTVERRARWVVRMLTSLLMFPG
Mb0310|M.bovis_AF2122/97 RVRNTAIARFRDSITHLLPSDIPPGKADLVVAELTAFAVALSDGVYFAGH
TH_2336|M.thermoresistible__bu LRTRPDWAEVVQRQMALLGDVQPGPGGR---VKAAVVMAGIAAAAGVDYG
:
MMAR_0237|M.marinum_M QSYDVTLDSAKQLLRGSLFAGAKPTATHRT------------
MUL_4876|M.ulcerans_Agy99 QSYDVTLDSAKQLLRGSLFAGAKPTATRRT------------
MLBr_02497|M.leprae_Br4923 RLGNKTARKHLHAAVRAVLEVGPPP-----------------
MAB_2466c|M.abscessus_ATCC_199 RPPDTATRSRLEAAVRAVLALNPPPANPKT------------
MAV_1113|M.avium_104 ALHDAAALQRLAAAVRAVLALTPPTTSTKPKPRTTLTKGAPR
Mvan_5831|M.vanbaalenii_PYR-1 HPPDPAARDRLTAAVRAVLALTPPTSRNTPAH----------
MSMEG_6556|M.smegmatis_MC2_155 RIADPTARRQLRAAVAAVLEVGPAPRAQRHRAQEAS------
Mflv_4881|M.gilvum_PYR-GCK RARQSIPAAADDIVADCARALICPN-----------------
Rv1255c|M.tuberculosis_H37Rv RDEADERAMIAEFVVPIVTPASAAARKAGHPGPE--------
Mb0310|M.bovis_AF2122/97 LEPDTTDVERMYRRLRQALEALIPVLLEET------------
TH_2336|M.thermoresistible__bu DLDEAALRDELLAAGRRTLGLRAPHARG--------------
.