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MATRRQMYAEQTRSDLLDSARRHFTTTGYNSVTVDDIVSSIEVSKGTFYYHFSDKQAMFTALLTECLTET ADTVTTGIRLLDKPGANGPQVAATSAWVYLSRSLHDRTYRELMRQAPMVLGEETYRHIDETIVLPPLVTL MDTLAARGELKAGVHTHMAARMLMTMFVTANSIIAESDDPATTMTEVADTIATMFSGIVLGDVPLSRAAA NG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_4648 | - | - | 100% (212) | TetR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_2290 | - | 1e-20 | 30.26% (195) | transcriptional regulator TetR |
| M. abscessus ATCC 19977 | MAB_4352c | - | 2e-09 | 22.11% (199) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0080 | - | 1e-09 | 26.80% (194) | transcriptional regulatory protein |
| M. gilvum PYR-GCK | Mflv_3666 | - | 5e-07 | 40.00% (60) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0078 | - | 1e-09 | 26.80% (194) | transcriptional regulatory protein |
| M. leprae Br4923 | MLBr_00717 | - | 1e-05 | 32.26% (62) | putative TetR-family transcriptional regulator |
| M. marinum M | MMAR_0224 | - | 9e-09 | 24.34% (189) | transcriptional regulatory protein |
| M. avium 104 | MAV_5253 | - | 6e-11 | 27.32% (205) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_2195 | - | 3e-08 | 36.92% (65) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_3094 | - | 2e-14 | 27.09% (203) | PUTATIVE putative transcriptional regulator, TetR family |
| M. ulcerans Agy99 | MUL_4890 | - | 5e-09 | 26.67% (210) | transcriptional regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_5881 | - | 1e-08 | 28.87% (142) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0080|M.bovis_AF2122/97 -MEIKRRTQEERSA---ATREALITGARKLWGLRGYAEVGTPEIATEAGV
Rv0078|M.tuberculosis_H37Rv -MEIKRRTQEERSA---ATREALITGARKLWGLRGYAEVGTPEIATEAGV
MMAR_0224|M.marinum_M -MEIKRRTQEERSA---ATREALITAARKLWGSRGYAEVGTPEIAAEAGV
MUL_4890|M.ulcerans_Agy99 -MESKRRTQEERSA---ATREALITAARKLWGSRGYAEVGTPEIAAEAGV
MAV_5253|M.avium_104 -MESKRRTQEERSA---ATRDALIAAARKLWGLRGYTEVGTPEIAAAAGV
TH_3094|M.thermoresistible__bu -MSKRGGRVEDRRARGDQTRRDLIDAGRALFVDPGYFHTSVGDLVERSGV
MAB_4648|M.abscessus_ATCC_1997 -MATRRQMYAEQTR------SDLLDSARRHFTTTGYNSVTVDDIVSSIEV
Mflv_3666|M.gilvum_PYR-GCK -MPRVTDDHLAARR------RQILDGARRCFAEYGYESATVRRLEQTIGL
Mvan_5881|M.vanbaalenii_PYR-1 MTSPPTKPPTTRQQGAARTRNALIDAGFRLAASGGLVGLSVNRIVEDAAV
MSMEG_2195|M.smegmatis_MC2_155 -MTEQLDRRADLTR------LQILQAASRQFARTPYSLVSLDDILADAQV
MLBr_00717|M.leprae_Br4923 -MTTARRRLSPEDR-----RAELLALGAEVFGKRPYDEVRIDEIAERAGV
:: . : :
Mb0080|M.bovis_AF2122/97 -TRGAMYHQFADKAALFRDVVEVVEQDVMARMATLVAASGAATPADAI-R
Rv0078|M.tuberculosis_H37Rv -TRGAMYHQFADKAALFRDVVEVVEQDVMARMATLVAASGAATPADAI-R
MMAR_0224|M.marinum_M -TRGAMYHQFADKAALFGEVVEAVEQDVMTRMATSVAASGAATPADAI-R
MUL_4890|M.ulcerans_Agy99 -TRGAMYHQFADKAALFGEVVEAVEQDVMTRMATSVTTSGAATPADAI-R
MAV_5253|M.avium_104 -TRGAMYHQFADKAALFRAVVEAVEQDVMARMAVVVAESGASTPTDAI-R
TH_3094|M.thermoresistible__bu GTRGAFYHHFPDKAALFRAVFEDVEQDLTLRSIASPPEG--SDSWERL-T
MAB_4648|M.abscessus_ATCC_1997 -SKGTFYYHFSDKQAMFTALLTECLTETADTVTTGIRLLDKPGANGPQ-V
Mflv_3666|M.gilvum_PYR-GCK -SRGAIFHHFRDKDTLFFELAR----EDAERMADVAAREGLIQVMRDM-L
Mvan_5881|M.vanbaalenii_PYR-1 -SKGSFFHHFGDRASYLVALHR----DFHDRILTEALAIIDGSAPGAR-R
MSMEG_2195|M.smegmatis_MC2_155 -TKGALYFHFRSKHALACAIVEYHAAQARDTTEDVAARNLSGLETLID-I
MLBr_00717|M.leprae_Br4923 -SRALMYHYFPDKRAFFAAVVKDEADRLYAATNIPPPAGLTMFEEVRVGV
::. ::. * .: : :
Mb0080|M.bovis_AF2122/97 AAVDAWLEVSG--DPEVRQLVLLDAPVVLGWAGFRD----VAQRYSLGMT
Rv0078|M.tuberculosis_H37Rv AAVDAWLEVSG--DPEVRQLILLDAPVVLGWAGFRD----VAQRYSLGMT
MMAR_0224|M.marinum_M AAVDAWLEVSG--DPEVRQLILLDAPAVLGWAGFRD----VAQRYSLGMT
MUL_4890|M.ulcerans_Agy99 AAVDAWLEVSG--DPEVRQLILLDAPAVLGWAGFCD----VAQRYSLGMT
MAV_5253|M.avium_104 AAVDAWLEVSA--DPEVRQLILLDAPSVLGWAEFRD----VAQRYSLGMT
TH_3094|M.thermoresistible__bu RGLHGFLDAAA--EPEVQRIILIDGPVVLGWQTLRS----IEERSSLAMI
MAB_4648|M.abscessus_ATCC_1997 AATSAWVYLSRSLHDRTYRELMRQAPMVLGEETYRH----IDETIVLPPL
Mflv_3666|M.gilvum_PYR-GCK AAPDQFDWLAT--RLEIARKLRNDPAFSQGWAERSA----ELS----AAT
Mvan_5881|M.vanbaalenii_PYR-1 LAIASRAYLDSCLTNRAVRALLLEARAEPAINDAVR----QRNSDTADLI
MSMEG_2195|M.smegmatis_MC2_155 SYQLAVDDVSD----PMTRAGLNLIESIGRTENLGA----KVVTDWVARF
MLBr_00717|M.leprae_Br4923 LAYMAYHKQNPEAAWAAYVGLGRSDPVLLGIDDEAKNRQMEHIMSRIGDV
Mb0080|M.bovis_AF2122/97 EQLITEAIRAGQLAR-QPVRPLAQVLIGALDEAAMFIATADDPKRARRET
Rv0078|M.tuberculosis_H37Rv EQLITEAIRAGQLAR-QPVRPLAQVLIGALDEAAMFIATADDPKRARRET
MMAR_0224|M.marinum_M EQLITEAIRAGQLDR-HPVRPLAHVLIGALDEAAMFIATADDPKRARRES
MUL_4890|M.ulcerans_Agy99 EQLITEAIRAGQLDR-HPVRPLAHVLIGALDEAAMFIATADDPKRARRES
MAV_5253|M.avium_104 EQLLTEAIRAGELAE-QPVRPLAHVLIGALDEAAMVIATADDPDRARRET
TH_3094|M.thermoresistible__bu QQILRRAIADGSIEE-QPVTALTHMLVSAVEEASLLIAHSTDPERARSDA
MAB_4648|M.abscessus_ATCC_1997 VTLMDTLAARGELKAGVHTHMAARMLMTMFVTANSIIAESDDPATTMTEV
Mflv_3666|M.gilvum_PYR-GCK TERLRRQKQAGRLRDDVDGEVLRTYLELVLDGLVARLASGDDP-----EK
Mvan_5881|M.vanbaalenii_PYR-1 EPDFTAMGWP-------HPRRAAQLWIGMTAEAALLEFDAGHKLTDLRAS
MSMEG_2195|M.smegmatis_MC2_155 SAIGRRAVSEGDLTPDSDPDVVARLLVSLYLG-VRQTSELEDPQRFLQDL
MLBr_00717|M.leprae_Br4923 VSVVPESKLHPDIERDLRVIVHGWLAFTFEVCRQRIMDPSTDADRLADSC
.
Mb0080|M.bovis_AF2122/97 RQVLRRLIDGMLNG------------------------------------
Rv0078|M.tuberculosis_H37Rv RQVLRRLIDGMLNG------------------------------------
MMAR_0224|M.marinum_M RQVLRRLIDGMLND------------------------------------
MUL_4890|M.ulcerans_Agy99 RQVLRRLIDGMLND------------------------------------
MAV_5253|M.avium_104 RQVLQRLVDGMFDAR-----------------------------------
TH_3094|M.thermoresistible__bu EAVLDTLLNALTRRRSRSR-------------------------------
MAB_4648|M.abscessus_ATCC_1997 ADTIATMFSGIVLGDVPLSRAAANG-------------------------
Mflv_3666|M.gilvum_PYR-GCK LSAVLDLVEASVRQP-----------------------------------
Mvan_5881|M.vanbaalenii_PYR-1 LARYIDADPALLGN------------------------------------
MSMEG_2195|M.smegmatis_MC2_155 ERSWQLVLPGIANPDRLGYLRQFIRRRTTLTARKAVPLHPEPPAHTRAGS
MLBr_00717|M.leprae_Br4923 AHALLDAIARVPEISKELADAMAIARQPPQ--------------------
Mb0080|M.bovis_AF2122/97 -
Rv0078|M.tuberculosis_H37Rv -
MMAR_0224|M.marinum_M -
MUL_4890|M.ulcerans_Agy99 -
MAV_5253|M.avium_104 -
TH_3094|M.thermoresistible__bu -
MAB_4648|M.abscessus_ATCC_1997 -
Mflv_3666|M.gilvum_PYR-GCK -
Mvan_5881|M.vanbaalenii_PYR-1 -
MSMEG_2195|M.smegmatis_MC2_155 A
MLBr_00717|M.leprae_Br4923 -