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SEAELRTPRADAARNRDQLLAAATRAFASADSEPSMRAIARQAGVGIATLYRHFPTRESLVDAVYRDQVV RLTTGAHELLGQLPPATAMRRWMDSFGDWIATKNGMLDTLHTMIESGHIGHAETRAELLKAVTTILDAGH AAGDLRADVTAEDIAASLIGIFTVAPRPEQEAQADRLLNLLMDGLRPAARQAHS*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. abscessus ATCC 19977 | MAB_1873c | - | - | 100% (195) | TetR family transcriptional regulator |
M. abscessus ATCC 19977 | MAB_0647 | - | 4e-20 | 33.15% (184) | transcriptional regulator TetR |
M. abscessus ATCC 19977 | MAB_4384 | - | 1e-15 | 30.00% (190) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb0068c | - | 3e-21 | 34.62% (182) | TetR family transcriptional regulator |
M. gilvum PYR-GCK | Mflv_0142 | - | 4e-19 | 34.07% (182) | TetR family transcriptional regulator |
M. tuberculosis H37Rv | Rv0067c | - | 3e-21 | 34.62% (182) | TetR family transcriptional regulator |
M. leprae Br4923 | MLBr_00316 | - | 1e-21 | 35.68% (185) | putative TetR/AcrR-family transcriptional regulator |
M. marinum M | MMAR_1145 | - | 2e-06 | 31.82% (110) | transcriptional regulatory protein |
M. avium 104 | MAV_4593 | - | 1e-42 | 49.15% (177) | TetR family protein transcriptional regulator |
M. smegmatis MC2 155 | MSMEG_3452 | - | 2e-33 | 42.16% (185) | TetR family protein transcriptional regulator |
M. thermoresistible (build 8) | TH_2975 | - | 3e-08 | 29.95% (187) | PUTATIVE putative transcription regulator AmtR |
M. ulcerans Agy99 | MUL_4780 | - | 4e-07 | 26.67% (210) | TetR family transcriptional regulator |
M. vanbaalenii PYR-1 | Mvan_1492 | - | 1e-18 | 34.57% (188) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment MAB_1873c|M.abscessus_ATCC_199 -------------MSEAELRTPRADAARNRDQLLAAATRAFASADSEPS- MAV_4593|M.avium_104 -------------------MVGRSDARRNRQRLLEAATAAFTAHGASVS- MSMEG_3452|M.smegmatis_MC2_155 --------------MANPTRRTRSDALQNRARILEVAAKAFAEQGLDTA- Mb0068c|M.bovis_AF2122/97 --------------MAPTDRRVRADAARNRARVLEVAYQTFAADGLSVP- Rv0067c|M.tuberculosis_H37Rv --------------MAPTDRRVRADAARNRARVLEVAYQTFAADGLSVP- MLBr_00316|M.leprae_Br4923 ---MSVPRSGLSVQMAQPARPLRADAARNRARILGVAYEAFATEGLSVP- Mflv_0142|M.gilvum_PYR-GCK -----------------MTRPLRADAARNRARVLEVAYDTFAAEGLTVP- Mvan_1492|M.vanbaalenii_PYR-1 --------------MTPPDRPVRADAARNRALLLAAAEEEFAERGPSAS- TH_2975|M.thermoresistible__bu VTAGGHPAAAPVTCGRPRSQERRRPGATARDEVLDAAAELFTTLGVAATS MMAR_1145|M.marinum_M ---------------MAATRTTARAGGDRRAAIIEAALNRFLSQGIDATA MUL_4780|M.ulcerans_Agy99 ----------------MVADFGRPRDPRIDGAVLRATVELLAETGYAGLL :: .: : . MAB_1873c|M.abscessus_ATCC_199 MRAIARQAGVGIATLYRHFPTRESLVDAVYRDQVVRLTTGAHELLGQLPP MAV_4593|M.avium_104 LESIARDAGVGIGTLYRHFPNREALVEAVYRAELAEVAAAAAQLLQRHPP MSMEG_3452|M.smegmatis_MC2_155 PAAIAKLAGVGIGTLYRHFPTRETLIDAAYRHQLTRVCDAVADLAARHPG Mb0068c|M.bovis_AF2122/97 VDEIARRAGVGAGTVYRHFPTKEALFQAVIADRMHRIIDKGHALLKSKHP Rv0067c|M.tuberculosis_H37Rv VDEIARRAGVGAGTVYRHFPTKEALFQAVIADRMHRIIDKGHALLKSKHP MLBr_00316|M.leprae_Br4923 IDEIARRAGVGAGTVYRHFPTKEALCAAVIGDRMPHLVDDGYVLLKSAGP Mflv_0142|M.gilvum_PYR-GCK IDEIARRAGVGAGTVYRHFPTKEALVVAVAEDRVRRIAERARTLLAVEGP Mvan_1492|M.vanbaalenii_PYR-1 VADIARRAGVAKGTVFRHFPTKEDLIAAIVSEHIAVLAAAARRLADSPDP TH_2975|M.thermoresistible__bu TRQIAESVGVRQASLYHHFRTKDEILATLLDATVAPSVTAARRLRGRPEP MMAR_1145|M.marinum_M LRQIQRDAGVSNGSFFHHFPSKEVLAAAVYVDCVTRYQQALLKDLARYPD MUL_4780|M.ulcerans_Agy99 VSAIAKRAGTSKPAIYRRWPSKAHLVHEAVFP-----IDAATAVPDTGSP * . .*. :.:::: .: : MAB_1873c|M.abscessus_ATCC_199 ATAMR---RWMDSFGDWIATKNGMLD-TLHTMIESG----HIGHAETRAE MAV_4593|M.avium_104 KAALR---RWMDRYATFVATKRGMAE-SLQAIFESG----ALVPSQTRDS MSMEG_3452|M.smegmatis_MC2_155 DEATR---RWMERFIDYATAKSGMSE-ALNAVIASG----ADPFADSLSM Mb0068c|M.bovis_AF2122/97 GDALF---AFLRSMVLQWGATDRG---LVEALAGVG-IEISSAAPEAEAD Rv0067c|M.tuberculosis_H37Rv GDALF---AFLRSMVLQWGATDRG---LVEALAGVG-IEISSAAPEAEAD MLBr_00316|M.leprae_Br4923 GEALF---TYLRSLVLHWGATDRG---LVDALAGAGGIDILGVAPDAEDA Mflv_0142|M.gilvum_PYR-GCK GQALF---VFFRDMVRS-AAVDHG---LVDALMNQG-LDLEAVAPGVEAA Mvan_1492|M.vanbaalenii_PYR-1 GAALL---EFLTIAADQRQRHDLT---FLQSASDGD-----PRVTEVRDA TH_2975|M.thermoresistible__bu PAVLLHALVWLDARLLWDSPHNLGILYLLPEVRDRRFGGFHRRRSELRAA MMAR_1145|M.marinum_M AESAVR--GIVGMHLSWCTEHPEMARFLITMTEPAVHRAAADELRSHNER MUL_4780|M.ulcerans_Agy99 VDDLREMVRRTTAVLSTPAAKAAQPG-LIGEMAADP-TLHSALLVRFGEI : MAB_1873c|M.abscessus_ATCC_199 LLKAVTTILDAGHAAGDLRADVTAEDIAASLIG--IFTVAPRPEQEAQAD MAV_4593|M.avium_104 IVGAVETLLRAGADDASLRADVQADDVVSSLIG--IFLVSGSPE---QTG MSMEG_3452|M.smegmatis_MC2_155 LTEAVGTLLEAGRRDHTLRTDVTAGDVLLFMGG--IAYAAQHGTR-DQAR Mb0068c|M.bovis_AF2122/97 FLDLLTDLLRAAQRAGTVRPDVDVLEVKTLLVG----CQAMQSYNAELAA Rv0067c|M.tuberculosis_H37Rv FLDLLTDLLRAAQRAGTVRPDVDVLEVKTLLVG----CQAMQSYNAELAA MLBr_00316|M.leprae_Br4923 FLTILSDLLYAAQYAGTARTDVGVREVKSILVG----CQAMEAYNSALAE Mflv_0142|M.gilvum_PYR-GCK FLSTLGDLLSAAQGAGTVRPDVDVAVVKALLVV----CKVPQVFDSEVTE Mvan_1492|M.vanbaalenii_PYR-1 LHANLETLVDRARTSGAIRADITEADVFLMMCAPIHIVENLPAPAPLLWQ TH_2975|M.thermoresistible__bu YRDLAERVAAAGATPSSVPDVVIDPDVVFRLVETLPNLRMDGLGEPDQPR MMAR_1145|M.marinum_M FATAVQTWWRPHAHYGALRPLSPAHSQALWLGPAQELVRAWLLGNLAAPP MUL_4780|M.ulcerans_Agy99 FGHGLTTWLDNAAARGQVRADVTAPELAEAIAG--IVLIGLLTRPGELEP : MAB_1873c|M.abscessus_ATCC_199 RLLNLLMDGLRPAARQAHS--------------- MAV_4593|M.avium_104 RMLDLLVAGVTR---------------------- MSMEG_3452|M.smegmatis_MC2_155 RLVDLFIDALTKDTRPDT---------------- Mb0068c|M.bovis_AF2122/97 KVTDVALDGLRANRK------------------- Rv0067c|M.tuberculosis_H37Rv KVTDVALDGLRANRK------------------- MLBr_00316|M.leprae_Br4923 RVTDVVVDGLRAAR-------------------- Mflv_0142|M.gilvum_PYR-GCK RVTRVIEDGLRPLR-------------------- Mvan_1492|M.vanbaalenii_PYR-1 RYLAIIFDGLRPDGAHPLPQPAPAAP-------- TH_2975|M.thermoresistible__bu RTADLAVHVLGWRGDWPRLRSESATVAAAVGDCR MMAR_1145|M.marinum_M NAADAAILADAAWLCLRAGPAG------------ MUL_4780|M.ulcerans_Agy99 GVGDAWIDRTTTLLLKGIRKGTPQ----------