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MAATRTTARAGGDRRAAIIEAALNRFLSQGIDATALRQIQRDAGVSNGSFFHHFPSKEVLAAAVYVDCVT RYQQALLKDLARYPDAESAVRGIVGMHLSWCTEHPEMARFLITMTEPAVHRAAADELRSHNERFATAVQT WWRPHAHYGALRPLSPAHSQALWLGPAQELVRAWLLGNLAAPPNAADAAILADAAWLCLRAGPAG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_1145 | - | - | 100% (205) | transcriptional regulatory protein |
| M. marinum M | MMAR_3853 | - | 4e-09 | 28.19% (149) | putative regulatory protein |
| M. marinum M | MMAR_5384 | - | 5e-07 | 49.02% (51) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0237 | - | 2e-08 | 30.77% (156) | TetR/ACRR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_4630 | - | 1e-09 | 27.43% (175) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0232 | - | 2e-08 | 30.77% (156) | TetR/ACRR family transcriptional regulator |
| M. leprae Br4923 | MLBr_00316 | - | 7e-06 | 39.71% (68) | putative TetR/AcrR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_1552 | - | 4e-27 | 34.92% (189) | TetR family transcriptional regulator |
| M. avium 104 | MAV_1669 | - | 3e-11 | 29.41% (153) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_3452 | - | 7e-09 | 30.99% (142) | TetR family protein transcriptional regulator |
| M. thermoresistible (build 8) | TH_4317 | - | 2e-06 | 24.78% (113) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_0910 | - | 1e-117 | 99.02% (205) | transcriptional regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_4092 | - | 3e-10 | 33.33% (108) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_1145|M.marinum_M ------------MAATRTTARAGGDRRAAIIEAALNRFLSQGIDATALRQ
MUL_0910|M.ulcerans_Agy99 ------------MAATRTTARAGGDRRAAIIEAALNRFLSQGIDATALRQ
MAB_1552|M.abscessus_ATCC_1997 --------MIQYSSGVPPASNAGVARRRAILDAALTSFLKSGVAGATVEA
Mb0237|M.bovis_AF2122/97 -------------MPTVTWARVDPARRAAVVEAAEAEFGAHGFSRGSLNV
Rv0232|M.tuberculosis_H37Rv -------------MPTVTWARVDPARRAAVVEAAEAEFGAHGFSRGSLNV
MAV_1669|M.avium_104 ---------------------MKSDRRLQLLSAAERLFAERGFLAVRLED
Mvan_4092|M.vanbaalenii_PYR-1 ---------MTTTDATSPRSRAKSDRRGQLIGAAERLIAEHGYLAVRLED
MLBr_00316|M.leprae_Br4923 MSVPRSGLSVQMAQPARPLRADAARNRARILGVAYEAFATEGLS-VPIDE
MSMEG_3452|M.smegmatis_MC2_155 -----------MANPTRRTRSDALQNRARILEVAAKAFAEQGLD-TAPAA
Mflv_4630|M.gilvum_PYR-GCK ----------------MSAEERHRNRRTRLIEAAMELIGTHGVAAATVTA
TH_4317|M.thermoresistible__bu ----------------------MSQQYDRMVDVVLSVLVSDGFEGVSVRK
. :: .. : *
MMAR_1145|M.marinum_M IQRDAGVSNGSFFHHFPSKE---VLAAAVYVDCVTRYQQALLKDLARY-P
MUL_0910|M.ulcerans_Agy99 IQRDAGVSNGSFFHHFPSKE---VLTAAVYVDCVTRYQQALLKDLVRY-P
MAB_1552|M.abscessus_ATCC_1997 LHRESGASVGSIYHFFGSKE---GVAAELYLETLRDYYNAYLAVLQSS-S
Mb0237|M.bovis_AF2122/97 IARRAGVAKGSLFQYFADKRDLYAFIADIASQRVRSYMEDLIRELDPN-R
Rv0232|M.tuberculosis_H37Rv IARRAGVAKGSLFQYFADKRDLYAFIADIASQRVRSYMEDLIRELDPN-R
MAV_1669|M.avium_104 IGASAGVSGPAIYRHFPNKE---SLLVELLVGISTRLLAGARQVRARS-A
Mvan_4092|M.vanbaalenii_PYR-1 IGAAAGISGPAIYRHFPNKE---ALLVELLVGISTRLLAGAVEVVDRAGD
MLBr_00316|M.leprae_Br4923 IARRAGVGAGTVYRHFPTKE---ALCAAVIGDRMPHLVDDGYVLLKSA-G
MSMEG_3452|M.smegmatis_MC2_155 IAKLAGVGIGTLYRHFPTRE---TLIDAAYRHQLTRVCDAVADLAARH--
Mflv_4630|M.gilvum_PYR-GCK VCAESGVTSRYFYQHFPDRD---ALLRAVYQQLYATFQEVIVDAIPDAGA
TH_4317|M.thermoresistible__bu VAARANVSIGAVQHHFPTKD---AMLQAAMDTAARRFRQRLAERMDPTMP
: :. . :.* : .
MMAR_1145|M.marinum_M DAESAVRGIVGMHLSWCTEHPEMARFLITMTEPAVHR-AAADELR-SHNE
MUL_0910|M.ulcerans_Agy99 DAESAVRGIVGMHLSWCTEHPEMARFLITMTEPAVHR-AAADELR-SHNE
MAB_1552|M.abscessus_ATCC_1997 GPHDGVVGAVSFHLQWVAANEMRARFLFHCREFEVIE-ESRSTIT-ALHE
Mb0237|M.bovis_AF2122/97 PFFEFLTDLLDGWVAYFAEHP-RERALHAAATLEVDT-DARISVRSVLHR
Rv0232|M.tuberculosis_H37Rv PFFEFLTDLLDGWVAYFAEHP-RERALHAAATLEVDT-DARISVRSVLHR
MAV_1669|M.avium_104 DAAAALDGLIDFHLDFALNEPDLIRIQDRDLAYLPKP-AER-QVRKAQRQ
Mvan_4092|M.vanbaalenii_PYR-1 DADSALEGLIDFHLDFVFGEPDLIRIQDRDLGNLPPA-AKR-QVRRKQRQ
MLBr_00316|M.leprae_Br4923 PGEALFTYLRSLVLHWGATDRGLVDALAGAGGIDILG-VAP-----DAED
MSMEG_3452|M.smegmatis_MC2_155 PGDEATRRWMERFIDYATAKSGMSEALNAVIASGADP-FAD------SLS
Mflv_4630|M.gilvum_PYR-GCK PPEVLAYAPIRGLVSMINNDPRLGRILFVESATEPLLRELRSDMMTGFTD
TH_4317|M.thermoresistible__bu AAEQLETVAVALACADPAERETAVTWLLRLARAAVNEQVAERHRS--EWR
MMAR_1145|M.marinum_M RFATAVQTWWRPHAHYGALRP-------------LSPAHSQALWLG----
MUL_0910|M.ulcerans_Agy99 RFATAVQTWWRPHAHYGALRP-------------LSPAHSQALWLG----
MAB_1552|M.abscessus_ATCC_1997 DFYSQASAWLQPHVEKRRIKP-------------LPPRLCQALWMG----
Mb0237|M.bovis_AF2122/97 HYLDVLRPLVRDAHARGDLRADSDTGALMSLLLLIFPHLALAPYMRGLDP
Rv0232|M.tuberculosis_H37Rv HYLDVLRPLVRDAHARGDLRADSDTGALMSLLLLIFPHLALAPYMRGLDP
MAV_1669|M.avium_104 YVEVWVGVLRELNPELAEADAR------------LTAHAVFGLLNS----
Mvan_4092|M.vanbaalenii_PYR-1 YVEIWVDVLRRRTPGLTETDAR------------LMAHAAFGLLNS----
MLBr_00316|M.leprae_Br4923 AFLTILSDLLYAAQYAGTARTD------------VGVREVKSILVG----
MSMEG_3452|M.smegmatis_MC2_155 MLTEAVGTLLEAGRRDHTLRTD------------VTAGDVLLFMGG----
Mflv_4630|M.gilvum_PYR-GCK LVLREARLHLDIADSAVGVAHLAS---------TLGVGGLFEVLRRWLDG
TH_4317|M.thermoresistible__bu ALEALLRDLIXXXHHARRACAD------------RGQLPHRAVLAG----
MMAR_1145|M.marinum_M ------PAQELVRAWLLGNLAAPPNAADAAILADAAWLCLRAGPAG--
MUL_0910|M.ulcerans_Agy99 ------PAQELVRAWLLGNLAAPPNAADAAILADAAWLCLRAGPAG--
MAB_1552|M.abscessus_ATCC_1997 ------PCVEYARLWLAR-SADFDMLAAAPVLGQAAWDAVKV------
Mb0237|M.bovis_AF2122/97 ILGLDEPTPEQPALAVRRLVAVLAAAFDAQHPATNSAQTRSEEIT---
Rv0232|M.tuberculosis_H37Rv ILGLDEPTPEQPALAVRRLVAVLAAAFDAQHPATNSAQTRSEEIT---
MAV_1669|M.avium_104 -------TPHSMKSQDSGRGKPARAARSRAIMRAMTVAALAAGNQCP-
Mvan_4092|M.vanbaalenii_PYR-1 -------TPHGVKP---GLNKAAEAS-SRTVLRTMTVAALTSAGRRA-
MLBr_00316|M.leprae_Br4923 -----------------CQAMEAYNSALAERVTDVVVDGLRAAR----
MSMEG_3452|M.smegmatis_MC2_155 ----------------IAYAAQHGTRDQARRLVDLFIDALTKDTRPDT
Mflv_4630|M.gilvum_PYR-GCK -------ELEFTTDELVQHCAGFLGSLGSYVLLQNAVESATTKAKPQS
TH_4317|M.thermoresistible__bu -------GQGTTAGGAAVRRVRHLSAAADAVLPEVPVQGRQLGPAQR-