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VQNPPYVETGYQYDLVTNALRDTGQLGRLKTGIGLLCFVIVFLQGVTQFYPLGPHGIWPRVVHGITAASA VVAGLCWLSFSWPGRRAMAAFVVWADVALAVGAALLSDPTARICAIVYLGPVGLLPTFFLSRRALVAHCA FATSLLGAVLAVNVLSGGARMFEQFFYAAPVISAIVLVPAVIQLVLEGGRDSILSAALAADRDPLTGLLN RRGVTSAMDLLHRGRLDAIDIVVVLMDVDGLKELNDTHGHGAGDMTLKAVADMLKARTRVGEIAARFGGD EFLVVAFPGRGEDIESTIRRVSAPRAGIDYWTVSVGAAWQSRTGNKVDLESLVQQADHALYEAKKTRGML DPQR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_1867 | - | - | 100% (354) | hypothetical protein MAB_1867 |
| M. abscessus ATCC 19977 | MAB_0124 | - | 1e-83 | 47.06% (340) | hypothetical protein MAB_0124 |
| M. abscessus ATCC 19977 | MAB_3940c | - | 2e-36 | 34.34% (332) | hypothetical protein MAB_3940c |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1389c | - | 1e-09 | 32.70% (159) | hypothetical protein Mb1389c |
| M. gilvum PYR-GCK | Mflv_0112 | - | 4e-28 | 31.33% (332) | diguanylate cyclase |
| M. tuberculosis H37Rv | Rv1354c | - | 1e-09 | 32.70% (159) | hypothetical protein Rv1354c |
| M. leprae Br4923 | MLBr_00397 | - | 6e-16 | 31.50% (200) | putative transporter protein |
| M. marinum M | - | - | - | - | - |
| M. avium 104 | MAV_1995 | - | 3e-28 | 30.77% (364) | diguanylate cyclase |
| M. smegmatis MC2 155 | MSMEG_2196 | - | 1e-11 | 33.54% (158) | sensory box/response regulator |
| M. thermoresistible (build 8) | TH_3406 | - | 2e-20 | 29.07% (313) | PUTATIVE diguanylate cyclase |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_2385 | - | 1e-28 | 30.84% (347) | diguanylate cyclase |
CLUSTAL 2.0.9 multiple sequence alignment
TH_3406|M.thermoresistible__bu -----MLKALRRTWRKPDHYYWFTSFLAARRARTSTCRFIASITLILGLM
Mvan_2385|M.vanbaalenii_PYR-1 -----MLGWWRGWWQRPDQFDWFSAYLRDRGLQVRWRMATFVFTVLLVAV
MAV_1995|M.avium_104 ------MKWLAAWWGQPDHFDWLTGYLQDHGFGTATRRAMAVVGASLVLV
Mb1389c|M.bovis_AF2122/97 ----------MCNDTATPQLEELVTTVANQLMTVDAATSAEVSQRVLAYL
Rv1354c|M.tuberculosis_H37Rv ----------MCNDTATPQLEELVTTVANQLMTVDAATSAEVSQRVLAYL
MSMEG_2196|M.smegmatis_MC2_155 ---------------MSESLDVLVTSVATQLMAVEAATSVSVSQQVLAEL
Mflv_0112|M.gilvum_PYR-GCK MVDGTVRTLLRQWWNQRDDYQWRIDFLRTRGLLPVLRYIIAGIGGSLGVL
MAB_1867|M.abscessus_ATCC_1997 -------MQNPPYVETGYQYDLVTNALRDTGQLGRLKTGIGLLCFVIVFL
MLBr_00397|M.leprae_Br4923 -------MDHTTKCDAEQYFQAIVTSMADGVIVVDIDGRIESIN------
:
TH_3406|M.thermoresistible__bu PMVMLAGPAGPQSMPGRLIAVAVTVTALVITLIWLRDRWPSRNQSRVVSL
Mvan_2385|M.vanbaalenii_PYR-1 PVVMVGSPAGPGGPLQTWIVIGAAASALAASLLWLFR-WPSRAQSLAYST
MAV_1995|M.avium_104 PANVLWGATPFFPGLTLTVSVLAGMVGLGMAVLWLHG-WPTRRQSVVFAL
Mb1389c|M.bovis_AF2122/97 VEQLGVDVS------------FLRHNDRDRRATRLVAEWPPRLNIPDPDP
Rv1354c|M.tuberculosis_H37Rv VEQLGVDVS------------FLRHNDRDRRATRLVAEWPPRLNIPDPDP
MSMEG_2196|M.smegmatis_MC2_155 VSFFDVDVS------------FLRHNDHRAHATRLVAEWPPRPVDAATDP
Mflv_0112|M.gilvum_PYR-GCK SVYNAFVPPGADGVLIRTGWAILAVGSLGWAARWALGSWPTVRESAALVV
MAB_1867|M.abscessus_ATCC_1997 QGVTQFYPLGPHGIWPRVVHGITAASAVVAGLCWLSFSWPGRRAMAAFVV
MLBr_00397|M.leprae_Br4923 ---------------------------------------PAATRILGLRA
*
TH_3406|M.thermoresistible__bu AAGLAIAVF--AFTLPDPSAGLVWTAAFAVLAGYVALFHSARYATFT--V
Mvan_2385|M.vanbaalenii_PYR-1 VCSVSIAAG--CLAIQDPYAGLMGCTMFAAIGGFVAYFHALAHVVAN--L
MAV_1995|M.avium_104 TGSVAIGAG--CLWQTEPLVGLMACSALSVTGGYNAFFHTAKFMGLN--F
Mb1389c|M.bovis_AF2122/97 LRLIYFADADPVFALCEHAKEPLVFRPEPATEDYQRLIEEARGVPVTSAA
Rv1354c|M.tuberculosis_H37Rv LRLIYFADADPVFALCEHAKEPLVFRPEPATEDYQRLIEEARGVPVTSAA
MSMEG_2196|M.smegmatis_MC2_155 IAVVHFADADPVFAMAEHLKEPAVFRPEPLYDDYQRTIEAGRHIPATSMA
Mflv_0112|M.gilvum_PYR-GCK FVDVMMTVS--ALLFGDPTLAMSGIPILLCAGGYVVFFHGPRLHLVHIAW
MAB_1867|M.abscessus_ATCC_1997 WADVALAVG--AALLSDPTARICAIVYLGPVGLLPTFFLSRRALVAHCAF
MLBr_00397|M.leprae_Br4923 HDVVDMKHG-------HPFCFYDTDNQRVDLEREVMRVVRREVTTVSKVV
: : . .
TH_3406|M.thermoresistible__bu LFAAITAGVLSFELAKTAGVAAAVCG-FVFITVVTFA---VVCACNLLVG
Mvan_2385|M.vanbaalenii_PYR-1 VVALSCATINAVRILVETDDIRIVAGSAALVLGLNLG---VPFGIHTLVH
MAV_1995|M.avium_104 GLAGAIGALQAARLAASGQAMLAFTG-YFLVLELNVI---VPLSIQIVVR
Mb1389c|M.bovis_AF2122/97 AVPLVSGEITTGLLGFIKFGDRKWHEAELNALMTIAT---LFAQVQARVA
Rv1354c|M.tuberculosis_H37Rv AVPLVSGEITTGLLGFIKFGDRKWHEAELNALMTIAT---LFAQVQARVA
MSMEG_2196|M.smegmatis_MC2_155 CVPLLSGDVTTGVLGFVKFGDREWLPAELNALKAIAS---LFAQVQARIE
Mflv_0112|M.gilvum_PYR-GCK CTASVVGIAIWLAVSDPVFGPQLAVSRAIIALAVTVC---VLPALQFGFW
MAB_1867|M.abscessus_ATCC_1997 ATSLLGAVLAVNVLSGGARMFEQFFYAAPVISAIVLVPAVIQLVLEGGRD
MLBr_00397|M.leprae_Br4923 GIDQHSGQRLWLSVNVSLLAYKAPPHSALVVSFSDIS---------AHHL
. :
TH_3406|M.thermoresistible__bu LLDVDVLDADIEPLTGLLNRDAFYRSAGHLISRSRDDDRQLVIALINIDN
Mvan_2385|M.vanbaalenii_PYR-1 SLHIDLRDSDRDPLTGLLNRRSFYNMVRDLIAARRQVNTPVNVTMVDLDD
MAV_1995|M.avium_104 ALWLDLLRANRDPLTGLLNRRACNRAIIGRMLTG-ASHMFLAVAMVDLDR
Mb1389c|M.bovis_AF2122/97 AEARLRYLADHDDLTGLHNRRALLQHLDQRLAPG--QPGPVAALFLDLDR
Rv1354c|M.tuberculosis_H37Rv AEARLRYLADHDDLTGLHNRRALLQHLDQRLAPG--QPGPVAALFLDLDR
MSMEG_2196|M.smegmatis_MC2_155 AEERLRYLADHDHLTGLYNRRALMAHLEARLAPG--QPGPVAVMFFDLDR
Mflv_0112|M.gilvum_PYR-GCK LLQDSSMQSLTDPLTELTNRRGLAVSVKRLNTDAR-ADATLCALLIDVDR
MAB_1867|M.abscessus_ATCC_1997 SILSAALAADRDPLTGLLNRRGVT-SAMDLLHRGRLDAIDIVVVLMDVDG
MLBr_00397|M.leprae_Br4923 SIERLTYEATHDCLTGLANRRFAEDQITKSLQHDE-RSRLAAVLLLDLDD
: : ** * ** :.::*
TH_3406|M.thermoresistible__bu LRLLRDTQGQAAADRARVAIGQTLRENTRHNAFVAHLGQDEFLIA--DTF
Mvan_2385|M.vanbaalenii_PYR-1 FKLLNDTHGHAVGDAALVSVAAVLQEHTEPGTVLGRLGGEEFVIA--DVD
MAV_1995|M.avium_104 FKALNDTHGHAAGDEALIAVAGALTAACGDTTVVGRVGGEEFLVA--DIV
Mb1389c|M.bovis_AF2122/97 LKAINDYLGHAAGDQFIHVFAQRIGDALVGESLIARLGGDEFVLIPASPM
Rv1354c|M.tuberculosis_H37Rv LKAINDYLGHAAGDQFIHVFAQRIGDALVGESLIARLGGDEFVLIPASPM
MSMEG_2196|M.smegmatis_MC2_155 LKAINDYLGHTAGDAFISILAQRLQRGDDAPKLIARLGGDEFVVVPDDPM
Mflv_0112|M.gilvum_PYR-GCK FKSVNDTFGHAVGDDVLIRTARRIRASVPEDAVVVRWGGEEFLVV--DRI
MAB_1867|M.abscessus_ATCC_1997 LKELNDTHGHGAGDMTLKAVADMLKARTRVGEIAARFGGDEFLVV----A
MLBr_00397|M.leprae_Br4923 FKVINDSLGHDVGDAVLQTVAQRLRSAVRPDDVVARLGGDEFIVLLRGPL
:: :.* *: ..* . : . : * :**::
TH_3406|M.thermoresistible__bu SSTDSFPLVERVRGAIATTPPRLTASIGVVSTPMRGLAVCPPETLLDELI
Mvan_2385|M.vanbaalenii_PYR-1 AAARHAITAERIRRGIAATPFQITASFGICSTTVAAGAEIDHPGFLDRLI
MAV_1995|M.avium_104 TTEQLPGWGQQLCEAVAALDPPVTASVGTATLPLRDLVSEYAEHAFHQLV
Mb1389c|M.bovis_AF2122/97 SADAAQPLAERLRDQLKDH-VAIGGEVLTRTVSIGVASGTPGQHTPSDLL
Rv1354c|M.tuberculosis_H37Rv SADAAQPLAERLRDQLKDH-VAIGGEVLTRTVSIGVASGTPGQHTPSDLL
MSMEG_2196|M.smegmatis_MC2_155 SLDEATALAYRLQSVLRER-VTVDGEMLTRTVSIGIAQGIPGKDSTSDVL
Mflv_0112|M.gilvum_PYR-GCK PGNQAETVAERIRAAVAEP------AEPTVTVSIGLATCERADIDLIDVI
MAB_1867|M.abscessus_ATCC_1997 FPGRGEDIESTIRRVSAPR---AGIDYWTVSVGAAWQSRTGNKVDLESLV
MLBr_00397|M.leprae_Br4923 SDMNANDVAKRLHTTLSESLVVDQLTVPIGASVGILEVRPDDRRRAADIL
: : ::
TH_3406|M.thermoresistible__bu AVASATMYEARRAGGNQARYRKYPNPTAVTEAHYPEQAADDF--------
Mvan_2385|M.vanbaalenii_PYR-1 RAADAAMYQSKRAGGNRVVHDRLDIPG-----------------------
MAV_1995|M.avium_104 AQADSAMYEAKRCGGNQTRHRPAQVST-----------------------
Mb1389c|M.bovis_AF2122/97 RRADQAALAAKHAGGDSVAIFTADMSVSGELRNDIELHLRRGIESDALRL
Rv1354c|M.tuberculosis_H37Rv RRADQAALAAKHAGGDSVAIFTADMSVSGELRNDIELHLRRGIESDALRL
MSMEG_2196|M.smegmatis_MC2_155 NRADHAVLTAKGSGGNRVAVFSDAMAMEIDFRNDIELHLQSVIEGGALVL
Mflv_0112|M.gilvum_PYR-GCK SAADAAMYEAKADGGNKVVITAEAA-------------------------
MAB_1867|M.abscessus_ATCC_1997 QQADHALYEAKKTRGMLDPQR-----------------------------
MLBr_00397|M.leprae_Br4923 RDADSAMYAAKNKKQCAVTPQQLVPFVALIALFVFFTAAAGAKFYAPSNL
*. : ::
TH_3406|M.thermoresistible__bu --------------------------------------------------
Mvan_2385|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_1995|M.avium_104 --------------------------------------------------
Mb1389c|M.bovis_AF2122/97 VYLPEVDLRTGDIVGTEALVRWQHPTRGLLAPGCFIP-----VAESINLA
Rv1354c|M.tuberculosis_H37Rv VYLPEVDLRTGDIVGTEALVRWQHPTRGLLAPGCFIP-----VAESINLA
MSMEG_2196|M.smegmatis_MC2_155 HYLPEIDMRTGEVLAAEALVRWEHPTRGLLSPDSFIG-----VAESINLA
Mflv_0112|M.gilvum_PYR-GCK --------------------------------------------------
MAB_1867|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_00397|M.leprae_Br4923 LVILQQTVVLAIVGYGMTFVIMAGSVDLSVGSIVALTGVTAALVAAQNQF
TH_3406|M.thermoresistible__bu --------------------------------------------------
Mvan_2385|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_1995|M.avium_104 --------------------------------------------------
Mb1389c|M.bovis_AF2122/97 GELDRWVLRRACNEFSEWQSAGLGHDALLRINVSAGQLVTGGFVDFVADT
Rv1354c|M.tuberculosis_H37Rv GELDRWVLRRACNEFSEWQSAGLGHDALLRINVSAGQLVTGGFVDFVADT
MSMEG_2196|M.smegmatis_MC2_155 GELGRWVLRTACAEFSRWRANGVGRNIVLRINVSPVQLVTDGFVESVAGI
Mflv_0112|M.gilvum_PYR-GCK --------------------------------------------------
MAB_1867|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_00397|M.leprae_Br4923 AAIVTALLVGLAAGMVNGIVFAYGKIPSFVSTLGMLQVCRGITLMISDSS
TH_3406|M.thermoresistible__bu --------------------------------------------------
Mvan_2385|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_1995|M.avium_104 --------------------------------------------------
Mb1389c|M.bovis_AF2122/97 IGQHGLDASSVCLEITENVVVQDLHTARATLARLKEVGVHIAIDDFGTGY
Rv1354c|M.tuberculosis_H37Rv IGQHGLDASSVCLEITENVVVQDLHTARATLARLKEVGVHIAIDDFGTGY
MSMEG_2196|M.smegmatis_MC2_155 MKEFGLPRGSVCLEITESVVVQDIETTRTTLTGLHNVGVQVAIDDFGTGY
Mflv_0112|M.gilvum_PYR-GCK --------------------------------------------------
MAB_1867|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_00397|M.leprae_Br4923 AKPMPFHGILGAMGAMPWILIVCLFVTILAGILFQFTMFGRWVKAIG-GN
TH_3406|M.thermoresistible__bu --------------------------------------------------
Mvan_2385|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_1995|M.avium_104 --------------------------------------------------
Mb1389c|M.bovis_AF2122/97 SAISLLQTLPIDTLKIDKTFVRQLGTNTSDLVIVRGIMTLAEGFQLDVVA
Rv1354c|M.tuberculosis_H37Rv SAISLLQTLPIDTLKIDKTFVRQLGTNTSDLVIVRGIMTLAEGFQLDVVA
MSMEG_2196|M.smegmatis_MC2_155 SVLSLLKSLPVDTLKIDRSFVAELGSNPGDLPIVRAVIALAGAFGLQLVA
Mflv_0112|M.gilvum_PYR-GCK --------------------------------------------------
MAB_1867|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_00397|M.leprae_Br4923 ERVATLAGVPTRGIKVAIFAICGLTAGLGGIVLASRLGAGTPTAATGFEI
TH_3406|M.thermoresistible__bu --------------------------------------------------
Mvan_2385|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_1995|M.avium_104 --------------------------------------------------
Mb1389c|M.bovis_AF2122/97 EGVETEAAARILLDQRCYRAQGFLFSRPVPGEAMRHMLSARRLPPTCIPA
Rv1354c|M.tuberculosis_H37Rv EGVETEAAARILLDQRCYRAQGFLFSRPVPGEAMRHMLSARRLPPTCIPA
MSMEG_2196|M.smegmatis_MC2_155 EGVETERAALTLLRHGCYRAQGFLLSKPILGSEMQTLLAKGRVPVHFSAA
Mflv_0112|M.gilvum_PYR-GCK --------------------------------------------------
MAB_1867|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_00397|M.leprae_Br4923 DVIAAVVIGGTPLTGGLGRLSGTLIGAIIISMLSNGMVFMGVGNAASQII
TH_3406|M.thermoresistible__bu ----------------------
Mvan_2385|M.vanbaalenii_PYR-1 ----------------------
MAV_1995|M.avium_104 ----------------------
Mb1389c|M.bovis_AF2122/97 TDPALS----------------
Rv1354c|M.tuberculosis_H37Rv TDPALS----------------
MSMEG_2196|M.smegmatis_MC2_155 PRM-------------------
Mflv_0112|M.gilvum_PYR-GCK ----------------------
MAB_1867|M.abscessus_ATCC_1997 ----------------------
MLBr_00397|M.leprae_Br4923 KGIMLAAAVFVFLQRRKIGIIK