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aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_3406 | - | - | 100% (378) | diguanylate cyclase |
| M. thermoresistible (build 8) | TH_3397 | - | 6e-08 | 21.59% (264) | PUTATIVE putative diguanylate cyclase |
| M. thermoresistible (build 8) | TH_0811 | - | 2e-05 | 27.71% (166) | sensory box/response regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_4894 | - | 1e-82 | 44.76% (353) | diguanylate cyclase |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | MLBr_01750 | - | 4e-06 | 35.63% (87) | hypothetical protein MLBr_01750 |
| M. abscessus ATCC 19977 | MAB_3940c | - | 2e-35 | 28.81% (361) | hypothetical protein MAB_3940c |
| M. marinum M | - | - | - | - | - |
| M. avium 104 | MAV_1995 | - | 2e-44 | 31.28% (358) | diguanylate cyclase |
| M. smegmatis MC2 155 | MSMEG_2774 | - | 2e-64 | 40.51% (353) | diguanylate cyclase |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_4819 | - | 4e-54 | 34.68% (346) | diguanylate cyclase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4894|M.gilvum_PYR-GCK MFEGLRRLSANSLAP--AVWRFDQYYWFTAILTARGFQTATGRLVAACIA
MSMEG_2774|M.smegmatis_MC2_155 -------MSP-----------FDHYYARTAMLSAQGQRSRMRRIIGVTIT
TH_3406|M.thermoresistible__bu MLKALRRTWR----------KPDHYYWFTSFLAARRARTSTCRFIASITL
MAV_1995|M.avium_104 ----MKWLAAWW-------GQPDHFDWLTGYLQDHGFGTATRRAMAVVGA
Mvan_4819|M.vanbaalenii_PYR-1 ----MQWDQ----------RRVDHYEWFSGFLDARGAKPAVRLLIASIAL
MAB_3940c|M.abscessus_ATCC_199 MIVSYIRSTAWMGFLRQWWTEPVPTGWLRGFLHARKLDRTVRNLIGGYAL
MLBr_01750|M.leprae_Br4923 ---------------------------MTRSLDELVTRVASKLMAATAAT
* .
Mflv_4894|M.gilvum_PYR-GCK AFGLLPLGVIAGVFGPQSLVAQILAGIVVIASLAMAMLWLREHWPTRAQS
MSMEG_2774|M.smegmatis_MC2_155 ALAFVPVLMLASPAGPAGALRYVPLGATACG-VLMSVWWWRRKWPSRNQS
TH_3406|M.thermoresistible__bu ILGLMPMVMLAGPAGPQSMPGRLIAVAVTVTALVITLIWLRDRWPSRNQS
MAV_1995|M.avium_104 SLVLVPANVLWGATPFFPGLTLTVSVLAGMVGLGMAVLWLHG-WPTRRQS
Mvan_4819|M.vanbaalenii_PYR-1 LMAGSVLLLIFSAGGPEGQPQRAMMWLSVAGGVAGVMLWLWH-WPSRLQS
MAB_3940c|M.abscessus_ATCC_199 IFAAICIAVQFSDTGPRSMIGRVIVGLCAVGSLGWALRWAVGPWPSLREA
MLBr_01750|M.leprae_Br4923 AVTISEGVLAILVEHFGVDVSFLRHNNHDIHETKLIVEWPPRDYVPDPDP
. : : * : . :.
Mflv_4894|M.gilvum_PYR-GCK LACVAAGALGIGISSLLVADPFVGFLGTAAFVPLTIFIVCFHAARVLALS
MSMEG_2774|M.smegmatis_MC2_155 WLVVGIGTVGIAVTLSSMSDPTVGLLSSSVFSLVTTYSAFLHSRRVLVLS
TH_3406|M.thermoresistible__bu RVVSLAAGLAIAVFAFTLPDPSAGLVWTAAFAVLAGYVALFHSARYATFT
MAV_1995|M.avium_104 VVFALTGSVAIGAGCLWQTEPLVGLMACSALSVTGGYNAFFHTAKFMGLN
Mvan_4819|M.vanbaalenii_PYR-1 AAFATVTAFSVALAGLAYPDPLAALLGCIAFTTNGAYLAFFHTTRLLLGN
MAB_3940c|M.abscessus_ATCC_199 VAFVAFADIGIAVACWQDSDPLAGLVGTVLFTPVGAYVSFFLANRLLVAH
MLBr_01750|M.leprae_Br4923 IGVVYFADADPVFAMAEYLKEPAVLRPEPANADYQR--RIEEGASVPAVS
. . :
Mflv_4894|M.gilvum_PYR-GCK WTVGALVLAVLVVRMGSTD-LAVALTGLVIAV-LINVFVAISCRTVIRLL
MSMEG_2774|M.smegmatis_MC2_155 WIASGLTVGFLAIRVAFTS-IPMALSGALVSG-LVIATTSMLCRMAIRLL
TH_3406|M.thermoresistible__bu VLFAAITAGVLSFELAKTAGVAAAVCGFVFIT-VVTFAVVCACNLLVGLL
MAV_1995|M.avium_104 FGLAGAIGALQAARLAASGQAMLAFTGYFLVL-ELNVIVPLSIQIVVRAL
Mvan_4819|M.vanbaalenii_PYR-1 IVIAIGVATVEAIQLAAQGRIALAAVDLFLVV-QINIAVPLAIRILLHAL
MAB_3940c|M.abscessus_ATCC_199 VAWCAPMIIALSSRLFAEGTVGAAMTALVKVTSMLLVVVLIPAVIQFGIA
MLBr_01750|M.leprae_Br4923 LACVPLLSGEITTGVLGFVKYGDREWHDDELR-ALQAIATLFAQLQARIV
: : .
Mflv_4894|M.gilvum_PYR-GCK KPD--AHHRDIEQLTGLLHR----DAFYNSVATLLASRSRSDDQYLVFVA
MSMEG_2774|M.smegmatis_MC2_155 DAGNVQHPNEIDRLTGLLNR----EAFEIQAATMLGSHSRHDDQYLVILA
TH_3406|M.thermoresistible__bu DVD--VLDADIEPLTGLLNR----DAFYRSAGHLIS-RSRDDDRQLVIAL
MAV_1995|M.avium_104 WLD--LLRANRDPLTGLLNR----RACNR-AIIGRMLTG-ASHMFLAVAM
Mvan_4819|M.vanbaalenii_PYR-1 RGD--LHYADHDPLTGLLNR----RAFRR-QILSLLARSHGEGRYLVVAL
MAB_3940c|M.abscessus_ATCC_199 VVRWDALAAQRDPLTGLLNRRGIYAEWQRLYGELRREQPLDGDQVTAAAI
MLBr_01750|M.leprae_Br4923 AEEQLRYLAEHDDLTGLLNR-------RALIAHLDERLADGQRGPVTLLF
: : *****:* .
Mflv_4894|M.gilvum_PYR-GCK VNIDSFSLLLGLSGSGGGNRARVTVGQALRETVRHNAIVAHVSDDDFVIA
MSMEG_2774|M.smegmatis_MC2_155 VGIDDMSLLSDMDGTHSTLHARVAVAQALRETVRHRVPLAHVSDSEFLIA
TH_3406|M.thermoresistible__bu INIDNLRLLRDTQGQAAADRARVAIGQTLRENTRHNAFVAHLGQDEFLIA
MAV_1995|M.avium_104 VDLDRFKALNDTHGHAAGDEALIAVAGALTAACGDTTVVGRVGGEEFLVA
Mvan_4819|M.vanbaalenii_PYR-1 MDLDHFKALNDARGHIAGDQALIAVADALRTTATSTAVVARSGGEEFLIA
MAB_3940c|M.abscessus_ATCC_199 VDIDRFKSINDRYGHGTGDRVLIDVAHALTCGTTGTSVVGRSGGEEFLVV
MLBr_01750|M.leprae_Br4923 LGLDRLKAVNDYLGHNAGDRLIEVFADRLREAAESLTVIARFGGDEFVVV
:.:* : : . * . .. * :.: . .:*::.
Mflv_4894|M.gilvum_PYR-GCK DTFTTSDASPLVERIRGAIAATPQR---LTASIGVVVTPLPPLAAEPPDE
MSMEG_2774|M.smegmatis_MC2_155 DVFKTNDPSPLVERMRLAISTTPMR---LTASIGTVCSPLAPLASLPAEQ
TH_3406|M.thermoresistible__bu DTFSSTDSFPLVERVRGAIATTPPR---LTASIGVVSTPMRGLAVCPPET
MAV_1995|M.avium_104 DIVTTEQLPGWGQQLCEAVAALDPP---VTASVGTATLPLRDLVSEYAEH
Mvan_4819|M.vanbaalenii_PYR-1 DVTGSPSAAAHYQQVCDAITALPVG---LTASIGTAVAALRDVPVEAFES
MAB_3940c|M.abscessus_ATCC_199 TVCPASAVAEFATRLRQAVTASMPAGIAVTASVGVAAQAVSRVVSATSQE
MLBr_01750|M.leprae_Br4923 PAESVS--VDVAESFAHRLQTRLQKQVVIDGEILTRTVSIGVATGLPGRD
. : : : ..: . .:
Mflv_4894|M.gilvum_PYR-GCK VLDKLIAISQQAIEQARMAGGNQVRYVLRPDLGEGDDNGDDWPEQNRPA-
MSMEG_2774|M.smegmatis_MC2_155 VLQELIDVAMRAMNESRAAGGNQTISVNYPTPTPNQE-------------
TH_3406|M.thermoresistible__bu LLDELIAVASATMYEARRAGGNQARYRKYPNPTAVTEAHYPEQAADDF--
MAV_1995|M.avium_104 AFHQLVAQADSAMYEAKRCGGNQTRHRPAQVST-----------------
Mvan_4819|M.vanbaalenii_PYR-1 TIDRLVSAADMAMYRAKRNGGNQCHHLDAWPPPGPA--------------
MAB_3940c|M.abscessus_ATCC_199 AIEVLTACADRAMYEAKHDGGDQSRILHADDDSEGRYLWRSGA-------
MLBr_01750|M.leprae_Br4923 TTSDLLRWADHAALSAKSDGSKVVVLDHGISAQHTLRTEVELHLAGMIDT
* : : :: *..
Mflv_4894|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_2774|M.smegmatis_MC2_155 --------------------------------------------------
TH_3406|M.thermoresistible__bu --------------------------------------------------
MAV_1995|M.avium_104 --------------------------------------------------
Mvan_4819|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_3940c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_01750|M.leprae_Br4923 DLVLHYLPEVDMSTGKVLGTEALVRWQHPTRGLLFPDSFIPVAESINLAG
Mflv_4894|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_2774|M.smegmatis_MC2_155 --------------------------------------------------
TH_3406|M.thermoresistible__bu --------------------------------------------------
MAV_1995|M.avium_104 --------------------------------------------------
Mvan_4819|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_3940c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_01750|M.leprae_Br4923 KLGRMVMHSACAEFSRWRSAGVGLDALLRINVSPVQLVAEGFVDNVAGTL
Mflv_4894|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_2774|M.smegmatis_MC2_155 --------------------------------------------------
TH_3406|M.thermoresistible__bu --------------------------------------------------
MAV_1995|M.avium_104 --------------------------------------------------
Mvan_4819|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_3940c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_01750|M.leprae_Br4923 DEFGLDGSMVCLEITENVVVQNIDATRKTLAGLKEVGVHLAIDDFGTGYS
Mflv_4894|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_2774|M.smegmatis_MC2_155 --------------------------------------------------
TH_3406|M.thermoresistible__bu --------------------------------------------------
MAV_1995|M.avium_104 --------------------------------------------------
Mvan_4819|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_3940c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_01750|M.leprae_Br4923 VLTHLKSLPVDTIKIDKSFVAELGSNASDLAIVRAIMALAKEFELEVVAE
Mflv_4894|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_2774|M.smegmatis_MC2_155 --------------------------------------------------
TH_3406|M.thermoresistible__bu --------------------------------------------------
MAV_1995|M.avium_104 --------------------------------------------------
Mvan_4819|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_3940c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_01750|M.leprae_Br4923 GVETAVAAQVLLELGCNRAQGFLLSRPVDGAAMESLLAKGVIPMALGTCQ
Mflv_4894|M.gilvum_PYR-GCK ------------
MSMEG_2774|M.smegmatis_MC2_155 ------------
TH_3406|M.thermoresistible__bu ------------
MAV_1995|M.avium_104 ------------
Mvan_4819|M.vanbaalenii_PYR-1 ------------
MAB_3940c|M.abscessus_ATCC_199 ------------
MLBr_01750|M.leprae_Br4923 SPEPSEHQIHRS