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WDAIARFSSRYAVLIIGLWVLLAGAGNLLVPQVESTAHNHARGFLPQDAPVNAAGAVMGRQFQDGAGNNL NYLVLESDHKLGPVEHQYHDRLLTTLRADTTHLDSAMDLWADPLTAEGALSPDGKAVYTMLRVNGELGAA KANDALAAVRKIVADQPAPPGTQAWVTGPGATIADELTAIDTQMLMITGVTVVLIAVLLFVVYRSVITAA IPLMTVGLGLAVARSIVAFLGERDLIEVSIFSVSLLAALVLGAATDYGIFLLGRYHEQRRSGVDHEQALV IANRSVAPVIAASGLTIAAALSCLLFAQVGMLRSAGLPCAIGILTGMVASLTLLPALIGLAGRRGLAQPR PLRGQPGRRWRRVGAMVSRWPGPVLAGSLLVLVVCALPVAGLRLGFDELAAQPLSTHANRGYQAMDRHFP PNRLLPEIVSIESDHDLRTPAGVIAVERVTKGLMEIPGIRMVQSASRPAGTIPEQAALTEQAGIIADQLD DGTAQMSQRLGAVDKLSATLSQFSGAIAQLQKGLAGGVNGLGELNGGIGDMHSGMKALQDNVSQVSGYME PLRNFTNGNPNCANDGICSLVLKAVEPMDSVVAATASLTASTTKFGAGAQGMQKSFSGAVDSVKNMRATV AQLGAITDQLTHAVGETRTMFSGLTEYLRAMREDFRSSGEGGYYLPQRAWQDPRFQRAAGLYFGPDGHST RMLVFGDGKVFGADGAHRSPQIMLAVSEATKEGTLAGSSVNLTGFGTGTAELRGYVSEDFLLLAAVALAL VFLIVLVMLRSPVAAAVVIGTVIISYASALGVTTLIWQDLLGRDLHWAVPSIALIALVAVGADYNLLLTM RMREEVFLHGAGLRTGMIRTFGGTGGVVTTAGIVFGITMFAMLSSDVLSIEQTGTTIGVGLMIDTLIVRT FVVPAIAGALGKWFWWSPVPLLRGLLFRWSKARSPRTAGVLSYLLTRPSRLERTGA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_1520c | - | - | 100% (967) | MmpL family membrane protein |
| M. abscessus ATCC 19977 | MAB_3201 | - | 0.0 | 40.45% (937) | putative membrane protein MmpL |
| M. abscessus ATCC 19977 | MAB_2210c | - | 0.0 | 39.08% (939) | MmpL family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1787 | mmpL14 | 0.0 | 40.41% (933) | transmembrane transport protein MmpL14 |
| M. gilvum PYR-GCK | Mflv_2705 | - | 1e-173 | 37.67% (953) | transport protein |
| M. tuberculosis H37Rv | Rv0402c | mmpL1 | 1e-179 | 37.11% (954) | transmembrane transport protein MmpL1 |
| M. leprae Br4923 | MLBr_02378 | - | 1e-170 | 35.64% (940) | hypothetical protein MLBr_02378 |
| M. marinum M | MMAR_4975 | - | 0.0 | 65.32% (963) | MmpL family transport protein |
| M. avium 104 | MAV_5284 | - | 0.0 | 50.48% (947) | membrane protein, MmpL family protein |
| M. smegmatis MC2 155 | MSMEG_0225 | - | 1e-179 | 37.23% (959) | MmpL4 protein |
| M. thermoresistible (build 8) | TH_3260 | - | 1e-171 | 36.39% (959) | PUTATIVE MmpL4 protein |
| M. ulcerans Agy99 | MUL_0757 | mmpL5 | 1e-164 | 35.84% (946) | transmembrane transport protein, MmpL5 |
| M. vanbaalenii PYR-1 | Mvan_3833 | - | 1e-172 | 37.21% (946) | transport protein |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_0225|M.smegmatis_MC2_155 --MSTP-DAPTEAIPSAHG--KYTNHGG--IAKLIRTLAVPIILVWVALI
TH_3260|M.thermoresistible__bu -MTANPGHVRTDEAPTDRLDIKVSTHGPSFISTWIRRLSLPIIVGWIALI
MUL_0757|M.ulcerans_Agy99 -MTATTTDTPTDVVPPAEH------PPRPFIPRMIRTFAVPLILGWVLLI
Mflv_2705|M.gilvum_PYR-GCK --MSSSRDRAALREP-------------RSVARWIRRLAVPIILGWLLLA
Mvan_3833|M.vanbaalenii_PYR-1 --MRAHADR-DLRDP-------------TPVARWIRRLAIPIILGWVLLV
MLBr_02378|M.leprae_Br4923 MTVKCANDLDTHTKP-------------PFVARMIHRFAVPIILVWLAIA
Rv0402c|M.tuberculosis_H37Rv --MRSQRLAGHLSAA----------------ARTIHALSLPIILFWVALT
MAB_1520c|M.abscessus_ATCC_199 --------------------------MWDAIARFSSRYAVLIIGLWVLLA
MMAR_4975|M.marinum_M --------------------------MWDRFTKITSRYAVLIVGLWIVGA
Mb1787|M.bovis_AF2122/97 ---------------------------MTAIGRLIHRYAIWIVGVWALAA
MAV_5284|M.avium_104 -----------------------MPDRPGILGRLTGRYALLVVGLWVLAA
:: :: *
MSMEG_0225|M.smegmatis_MC2_155 AVLNTIVPQLEEVGEMRSVSMSPDDAPSMIAMKRVGEVFEEFKSNSSVMI
TH_3260|M.thermoresistible__bu ALLNITVPQLEVVGEMRAVSMSPDEAPSMVAMKRVGELFDEGSSDSQVMI
MUL_0757|M.ulcerans_Agy99 AVLNSVVPQLEVVGQMQAVSMSPDAAPSMISMKHIGKVFREGDSDSAAMI
Mflv_2705|M.gilvum_PYR-GCK VALNALVPQLEVVAAKNAVSMSPSNAPSMQAMADMGRLFEESDSDSIALI
Mvan_3833|M.vanbaalenii_PYR-1 AALNLLVPQLEVVAAQNAVSMSPSDAPAMQAMSDMGRLFGESDSDSIAMV
MLBr_02378|M.leprae_Br4923 VTVSVFIPSLEDVGQERSVSLSPKDAPSYIAMQKMGQVFNEGNSDSVIMI
Rv0402c|M.tuberculosis_H37Rv IVVNVVAPQLQSVARTHSVALGPHDAPSLIAMKRIGKDFQQFDSDTTAMV
MAB_1520c|M.abscessus_ATCC_199 GAGNLLVPQVESTAHNHARGFLPQDAPVNAAGAVMGRQFQDGAGNNLNYL
MMAR_4975|M.marinum_M TVGNLLIPQAESTARSHGRGFLPADAPVSVAGARMGEQFRDGNAGNINYL
Mb1787|M.bovis_AF2122/97 IIGNNFAPPLEQVITAEDQPFSPAGTATSRAVERSAAAFSQAPGDNIGYL
MAV_5284|M.avium_104 AVANVAVPQLERVVDSHARSFMPPSAPSAVAAARAAQLFDQTPSNNFVYV
. * : . . : * :. : . * : ... :
MSMEG_0225|M.smegmatis_MC2_155 VLEGE--QPLGDEAHKYYDEIVDKLEADKTHIEHVQDFWGDPLTASGAQS
TH_3260|M.thermoresistible__bu VLEGE--EPLGADARAFYDELVKRLEADDAHVENVQDLWSDPLTATGVQS
MUL_0757|M.ulcerans_Agy99 VLEGQ--EPLGAAAHKFYDKMITKLRADTKHVQSVQDFWGDPLTATGAQS
Mflv_2705|M.gilvum_PYR-GCK VLESETDQPLGDDAHEYYDGLIAALLADTENVRNIQDTWGDPLTEAAAQS
Mvan_3833|M.vanbaalenii_PYR-1 VLEGE--QPLGDDAHAYYDQLIEKLEAAPDHVRNIQDMWGDPLTEAAAQS
MLBr_02378|M.leprae_Br4923 VLEGD--KPLGDDAHRFYDGLIRKLRAD-KHVQSVQDFWGDPLTAPGAQS
Rv0402c|M.tuberculosis_H37Rv LLEGQ--EKLGDEAHRFYDVLVTKLSQDTTHVQHIENFWGDPLTAAGSQS
MAB_1520c|M.abscessus_ATCC_199 VLESD--HKLGPVEHQYHDRLLTTLRADTTHLDSAMDLWADPLTAEGALS
MMAR_4975|M.marinum_M VLESD--HRLGPAERAFYDKLLAKLRSDPTSLVSAMDLWSDPYTAKAAVS
Mb1787|M.bovis_AF2122/97 VLERN--GVLNDQDRAYYDALVVALRRDSRHVIEVVDWWGTPAIAEVARS
MAV_5284|M.avium_104 VLERN--QRLGAGDRQFYDALAAALGSDHRHVYAVTDLWSQPATAAGAQS
:** : *. : ::* : * : : *. * *
MSMEG_0225|M.smegmatis_MC2_155 SDGLASYVQVYTAGNQGEALANESVKAVQDIVDSV---QAPPGVTAYVTG
TH_3260|M.thermoresistible__bu PDGKSAYVQVKLAGNQGEALANESVETVREMIATVSEEMAPEGVQAFVTG
MUL_0757|M.ulcerans_Agy99 GDGKAAYVQVKLAGNQGESLANESVEAVKTIVDSL---QAPPGVKVYVTG
Mflv_2705|M.gilvum_PYR-GCK SDGRAAYATLNLAGNMGETESNEAVAAVRDIVANS---PPPPGVTVHVTG
Mvan_3833|M.vanbaalenii_PYR-1 TDGHAAYVALNLAGNMGETKSNESVAAVRDIVADS---PPPPGVQVHVTG
MLBr_02378|M.leprae_Br4923 NDGKAAYVQLSLAGNQGELLAQESIDAVRKIVVQT---PAPPGITAWVTG
Rv0402c|M.tuberculosis_H37Rv ADGKAAYVQLNLTGDQGGSQANESVAAVQRIVDSV---PPPPGIKAYVTG
MAB_1520c|M.abscessus_ATCC_199 PDGKAVYTMLRVNGELGAAKANDALAAVRKIVADQP---APPGTQAWVTG
MMAR_4975|M.marinum_M TDGEAEYTMLRLAGDLGAAQANAALDAVRRTVADQP---TPPGLRAYVTG
Mb1787|M.bovis_AF2122/97 DDHHAVTAALRFGGMVGTSQAGESITAARSIVTQLH---PPDGLHVFVTG
MAV_5284|M.avium_104 TDGQAVSVMVRLAGMLGTAQARDSVNAVRATAQKLG---PPAGLQVHVTG
* : . : * * : :: :.: .* * . ***
MSMEG_0225|M.smegmatis_MC2_155 PAAMSADQQIAGDRSMRMIEALTFTVIIIMLLMVYRSIITVILSLVMVVF
TH_3260|M.thermoresistible__bu GAAMSADQQEAGDSSLRVIEALTFLVITTMLLFVYRSVITVLIALFMVLI
MUL_0757|M.ulcerans_Agy99 SAALVADQQLAGDRSLQLIEMVTFTVIIVMLLLVYRSIITAAIMLTMVVL
Mflv_2705|M.gilvum_PYR-GCK PAALIADVNIAGERSMALVLLVTFVVIIVLLLFFYRSISTVLLLLVVVGI
Mvan_3833|M.vanbaalenii_PYR-1 PAALTADVNIAGESSMALILLVTFVVIIVLLLFFYRSITTVVLLLIMVGV
MLBr_02378|M.leprae_Br4923 ASALIADMHHSGDKSMIRITATSVIVILVTLLLVYRSFITVILLLFTVGI
Rv0402c|M.tuberculosis_H37Rv PGPLGADRVVYGDRSLHTITGISIAVIAIMLFIAYRSLSAALIMLLTVGL
MAB_1520c|M.abscessus_ATCC_199 PGATIADELTAIDTQMLMITGVTVVLIAVLLFVVYRSVITAAIPLMTVGL
MMAR_4975|M.marinum_M PGATVADEFGEIDRQMLLLTGVTVVLIALLLLAVYRSVITAAIPLVAVGL
Mb1787|M.bovis_AF2122/97 PGATIVDEFAAIDRQTQLITATTIVVLLILLLIVYRSAITATVPLLSVVV
MAV_5284|M.avium_104 PGATIVDEFSAIDRQMLGITAATIGLILLLLLVVYRSPVAAAIPLISVGL
.. .* : . : :. :: *: *** :. : * * .
MSMEG_0225|M.smegmatis_MC2_155 SLAAARGVIAFLGYYEIIGLSTFATNLLVTLAIAAATDYAIFLIGRYQEA
TH_3260|M.thermoresistible__bu GLLTTRGVVAFLGYHNIIGLSTFATSLLVTLAIAIAVDYAIFLIGRYQEA
MUL_0757|M.ulcerans_Agy99 GLLATRGGVAFLGYHRIIGLSTFATNLLVVLAIAAATDYAIFLIGRYQEA
Mflv_2705|M.gilvum_PYR-GCK QLLVARGVVAALAHVGVIGLSTYATNLLISLAVAAGTDYAIFLVGRYQEA
Mvan_3833|M.vanbaalenii_PYR-1 QMSVARGVVAALGHFQVIGLSTFAVNLLISLAVAAGTDYAIFLVGRYQEA
MLBr_02378|M.leprae_Br4923 ESAVARGVVALLGHTGLIGLSTFAVNLLTSLAIAAGTDYGIFITGRYQEA
Rv0402c|M.tuberculosis_H37Rv ELLAVRGIISTFAVNDLMGLSTFTVNVLVALTIAASTDYIIFLVGRYQEA
MAB_1520c|M.abscessus_ATCC_199 GLAVARSIVAFLGERDLIEVSIFSVSLLAALVLGAATDYGIFLLGRYHEQ
MMAR_4975|M.marinum_M GLAVGRSIVSLLGQHNLLEVSVFSVALLGAMVLGGATDYAIFLLGRYHEA
Mb1787|M.bovis_AF2122/97 SLAVAKPIVSVLVDRDFIGISLFSLGLSVAVVVGAGTGFAMFLIGRYHER
MAV_5284|M.avium_104 ALALARAVVAALGQANVVEVSLFSVALMAAMTLGAGTDYAIFLVGRYHEA
: :: : .: :* :: : :.:. ...: :*: ***:*
MSMEG_0225|M.smegmatis_MC2_155 RSVGESREQAYYTMFHSTAHVVLGSGMTIAGATL---CLHFTRMPYFQSL
TH_3260|M.thermoresistible__bu RSVGADRATAYHTMFGGTAHVILASGLTIAGATF---CLSFTRLPYFQSL
MUL_0757|M.ulcerans_Agy99 RGLGQDRESAYYTMFGGTAHVVLGSGLTIAGATF---CLSFTRLPYFQTL
Mflv_2705|M.gilvum_PYR-GCK RASGADHEEAYYEMFHGTAHVVLGSGLTIAGAML---CLSFTRMPYFQSM
Mvan_3833|M.vanbaalenii_PYR-1 RASGADPEAAYYEMFGGTAHVVLGSGLTIAGAMY---CLSFARMPYFQSM
MLBr_02378|M.leprae_Br4923 RQANENKEAAFYTMYRGTFHVILGSGLTISGATF---CLSFARMPYFQTL
Rv0402c|M.tuberculosis_H37Rv RATGQNREAAYYTMFGGTAHVVLASGLTVAGAMY---CLGFTRLPYFNTL
MAB_1520c|M.abscessus_ATCC_199 RRSGVDHEQALVIANRSVAPVIAASGLTIAAALS---CLLFAQVGMLRSA
MMAR_4975|M.marinum_M RRDGVEHEQALLAANRNVMPVVLASALTLAAALS---CLTFADVGLLRSA
Mb1787|M.bovis_AF2122/97 RRQHIAPAAALADAYRGVAPAIAGATFIVVTSLGAVGWLSLARIGMFATT
MAV_5284|M.avium_104 RRGGVAPAQALTVAYRSIAPVVIGSALTVSVAL---ACLVFAHVGSFRSA
* * . .: .: : : : * :: : : :
MSMEG_0225|M.smegmatis_MC2_155 GIPLAIGMTVVVLTALAVGPAIITVASRFGKTLEPK--RAMRTRGWRKVG
TH_3260|M.thermoresistible__bu GPPLAIGMIVLIVTSLTMGPAIITVATRFG-LLEPK--RAARVRFWRKVG
MUL_0757|M.ulcerans_Agy99 GVPLAIGMVIVVATALTLGPALIAVMSRFGKLLEPK--RMARVRGWRKIG
Mflv_2705|M.gilvum_PYR-GCK GIPCAVGIAAGVAVALTLGPAIVTVGSRFN-LLEPK--RAMRIRAWRRIG
Mvan_3833|M.vanbaalenii_PYR-1 GVPCAVGILAGVAVALTLGPAIVTVGSRFG-LLEPK--RAMRIRAWRRVG
MLBr_02378|M.leprae_Br4923 GVPCAVGMLIAVAVALTLGPAVLTVGSRFG-LFEPK--RLIKVRGWRRIG
Rv0402c|M.tuberculosis_H37Rv ASPCAIGLVTVMLASLTLAPAIIAVASRFG-LFDPK--RATTKRRWRRIG
MAB_1520c|M.abscessus_ATCC_199 GLPCAIGILTGMVASLTLLPALIGLAGRRG-LAQPRPLRGQPGRRWRRVG
MMAR_4975|M.marinum_M GLPCAVGVLIGMLASLTLLPALLDLAGRRG-LAQPRTVNRPIHRRWRRIG
Mb1787|M.bovis_AF2122/97 GILCSIGVLAVGLAALTLTPALVALASRAN-LLKPP-QHKRIQRQFRRLG
MAV_5284|M.avium_104 GLPCAIGILATMVAALTLTPALMSLAVRRR-YLEP--RPSRTARRWRRVG
. ::*: .:*:: **:: : * .* * :*::*
MSMEG_0225|M.smegmatis_MC2_155 AAVVRWPGPILVAAVGLSMIGLLALPGYRTNYNDRDYQPADLPANSGYAA
TH_3260|M.thermoresistible__bu ASVVRWPGPIMVTTVAVTLVGLLALPGYRTNYNDRNYLPASFPSNAGYEA
MUL_0757|M.ulcerans_Agy99 AAIVRWPGPILIGAVALALVGLLTLPGYKTNYNDRNYLPADLPANEGYSA
Mflv_2705|M.gilvum_PYR-GCK TMVVRWPGPILVASLALALVGLAALPGYQTSYDDTRYVPESIPANAGLQA
Mvan_3833|M.vanbaalenii_PYR-1 ATVVRWPGPILVASLALALIGLAALPGYKTSYDDTRYIPESIPANAGLQA
MLBr_02378|M.leprae_Br4923 TVVVRWPLPILITTCAIAMVGLLALPGYRTNYKDRAYLPASIPANQGFAA
Rv0402c|M.tuberculosis_H37Rv TVVVRWPGPVLAATLLIALIGLLALPKYQTNYNERYYIPSAAPSNIGYLA
MAB_1520c|M.abscessus_ATCC_199 AMVSRWPGPVLAGSLLVLVVCALPVAGLRLGFDELAAQPLSTHANRGYQA
MMAR_4975|M.marinum_M TMVARWPGPVLVAAALVLLICTLPITGLTLGFNEPAAEPDSTLANRGYQA
Mb1787|M.bovis_AF2122/97 THVARWPAPILVASGVFVLIMMIALPRVPIGWDEAAATPSAAESNRGYRA
MAV_5284|M.avium_104 TTVARWPGPILVAALGLTLLVALPLAGMRIGFNEPAATPSSTDSNRGYAS
: : *** *:: : . :: .:. .:.: * :* * :
MSMEG_0225|M.smegmatis_MC2_155 ADRHFSQARMNPELLMIESDHDLRNSADFLVIERIAKRVVGVPGVSRVQA
TH_3260|M.thermoresistible__bu AERHFDPARLNPELLLIESDHDLRNPADFLVIEKIAKAVFQVEGISRVQG
MUL_0757|M.ulcerans_Agy99 AERHFSQARMNPEVLMVESDHDMRNSSDFLVINKIAKAIFGVEGISRVQA
Mflv_2705|M.gilvum_PYR-GCK ATQHFTLSRMSPEILIVEADRDLRNPADFLVLDRLAKRVFAVEGVARVQA
Mvan_3833|M.vanbaalenii_PYR-1 ATKYFSLSRMSPEVLIVEADRDLRNSSDFLILDRLAKRVFNVEGVARVQA
MLBr_02378|M.leprae_Br4923 ADRHFPQARMKPEILMIESDHDMRNPADFLILDKLARGIFRVPGISRVQA
Rv0402c|M.tuberculosis_H37Rv SDRHFPQARMEPEVLMVEADHDLRNPTDMLILDRIAKTVFHTPGIARVQS
MAB_1520c|M.abscessus_ATCC_199 MDRHFPPNRLLPEIVSIESDHDLRTPAGVIAVERVTKGLMEIPGIRMVQS
MMAR_4975|M.marinum_M TDRHFPPNQLLPETVSIETDHDLRNPTGVIAIERVTRQLMTIPGIRMVQS
Mb1787|M.bovis_AF2122/97 ADRHFAPNQLLPTQVMIETDHDIRNPAGLTAIERITAAIMAIGGVRMVQS
MAV_5284|M.avium_104 AGRHFPENALLPDVIAIRADHDLRNPAGLIAIERITRHIMAVPGVRAVQS
::* : * : :.:*:*:*..:.. ::::: :. *: **.
MSMEG_0225|M.smegmatis_MC2_155 ITRPQGTPIEHTSIPFTISMQGTTQTMNQKYMQDRMADMLVQADQMQVTV
TH_3260|M.thermoresistible__bu ITRPEGTPIEHSSIPFMISQQGTLQILNQQYMQDRMADMLVQADEMQLMI
MUL_0757|M.ulcerans_Agy99 ITRPDGKPIEHTSIPFLISMQGTSQKLTEKYNQDLTTSMLQQVNDIQTNI
Mflv_2705|M.gilvum_PYR-GCK PSRPDGSPIAKTSIPFLISMQGVGQQQNMKLMQDRMDDMRTQADNLGKTL
Mvan_3833|M.vanbaalenii_PYR-1 PSRPDGAPIAHTSIPFLISMQGVGQQQNMKLMKDRIADMRVQADDIGETI
MLBr_02378|M.leprae_Br4923 ITRPDGTAMDHTSIPFQISMQNAGQVQTMKYQKDRMNDLLRQAENMAETI
Rv0402c|M.tuberculosis_H37Rv ITRPLGAPIDHSSIPFQLGMQSTMTIENLQNLKDRVADLSTLTDQLQRMI
MAB_1520c|M.abscessus_ATCC_199 ASRPAGTIPEQAALTEQAGIIADQLDDGTAQMSQRLGAVDKLSATLSQFS
MMAR_4975|M.marinum_M ASRPAGSVPDEATLANQAGAIGDRLDQRIAQLDHRFSSINVIAPTLSRFS
Mb1787|M.bovis_AF2122/97 ASHPNGMVSKQAALTASAGNLGDQLDEFSDQLTSRQATFTNLEAAVRDVV
MAV_5284|M.avium_104 ASRPDGKVPEQATLSYQAGVLGRQFGDTVDSLTQRLARVSELDGALAQTQ
::* * .:::. . . :
MSMEG_0225|M.smegmatis_MC2_155 DTMTKMIALMEQMRDTMNSMVGKMHGMVDDIKELRDNISDFDDFFRPIRN
TH_3260|M.thermoresistible__bu DTMDKMIALMEEMVETTDNMVRDMDEMAAHVAEMRDSISEFDDFFRPIRN
MUL_0757|M.ulcerans_Agy99 DQMERMHDLTQQMADVTHQMVIQMKGMVVDVEELRNHIADFDDFFRPIRS
Mflv_2705|M.gilvum_PYR-GCK GTMRTMYGLMTRLSEVTTVMIDDFTEMQQTVHQIRDMVANFDDQFRPVRN
Mvan_3833|M.vanbaalenii_PYR-1 ATMKTMYGLMTKFSNITTVMIDDMTEMRDTVHQIRDMVATFDDQFRPIRN
MLBr_02378|M.leprae_Br4923 ASMRRMHQLMALLTENTHHILNDTVEMQKTTSKLRDEIANFDDFWRPIRS
Rv0402c|M.tuberculosis_H37Rv DITQRTQELTRQLTDATHDMNAHTRQMRDNANELRDRIADFDDFWRPLRS
MAB_1520c|M.abscessus_ATCC_199 GAIAQLQKGLAGGVNGLGELNGGIGDMHSGMKALQDNVSQVSGYMEPLRN
MMAR_4975|M.marinum_M AAISRLQEQLSGSANGLGRVNSGIDAMDSGLVQLHDTAAQVSGYLNPLRD
Mb1787|M.bovis_AF2122/97 SALDLVQAGIRQDGYGLGQVSLAVRLMQQAITKLQGSAGDVFDIFDPLRR
MAV_5284|M.avium_104 QAVDGLGNGLHGGSAGLADMSGAADDMRAGMDGLQRNVTTVSGYLDPLRD
: * :: . . *:*
MSMEG_0225|M.smegmatis_MC2_155 YLYWEPHCYNIPMCYSLRSIFDTMDGIDTMTADFEQIVPDMDRMNALIPV
TH_3260|M.thermoresistible__bu YFYWEPHCYNIPVCWAMRSVFDTLDGINTMTDDIQNMLPHMHRLNDLMPQ
MUL_0757|M.ulcerans_Agy99 YFYWEKHCFDIPVCWSLRSVFDTLDGVDLMTEDINNLLPLMERLDTLMPQ
Mflv_2705|M.gilvum_PYR-GCK YFYWEPHCYNIPLCWSFRSLFDSMDGISTMTESFDKALVNMETMRSLLPQ
Mvan_3833|M.vanbaalenii_PYR-1 YFYWEPHCYNIPLCWSFRSLFDSMDGISVMTDTFDKAVANMDEMKALLPQ
MLBr_02378|M.leprae_Br4923 YFYWERHCFNIPICWSFRSIFDALDGVDQIDERLNSIVGDIKNMDLLMPQ
Rv0402c|M.tuberculosis_H37Rv FTYWERHCFDIPICWSMRSLLNSMDNVDKLTEDLANLTDDTERMDTTQRQ
MAB_1520c|M.abscessus_ATCC_199 FTNGNPNCANDGICSLVLKAVEPMDSVVAATASLTASTTKFGAGAQG---
MMAR_4975|M.marinum_M YTNSVANCPSDPVCALVLKVIDPADSIVVETNSLAKGTSQLGAGMSD---
Mb1787|M.bovis_AF2122/97 FVAAIPECRANPVCSVAQEVVQWANTVTESCAKLADAAGQLARGIADVAS
MAV_5284|M.avium_104 LVGRTPDCAANPICSMVDRVLAPVDSLVQTSAQLGSGAAKLTTGSN---T
.* :* . : : :
MSMEG_0225|M.smegmatis_MC2_155 MIANMEPMITTMKTMKTMMLTMQATNAGLQDQMAAMQ--------ENSTA
TH_3260|M.thermoresistible__bu MLTLLPTTVATMKTMRSMLLTMQATNAGLQDQMAEMQ--------ENANA
MUL_0757|M.ulcerans_Agy99 MTAMMPEMIQTMKSMKAQMLSMHSTQQGLQDQMAAMQ--------EDSSA
Mflv_2705|M.gilvum_PYR-GCK MLATFPPMIETMESMRQMMLTTYATMGGFYDQMDELT--------QDSTE
Mvan_3833|M.vanbaalenii_PYR-1 MLATFPPMIETMESMRQMMLTTYATMGGFYDQMDELT--------RDSTE
MLBr_02378|M.leprae_Br4923 MLEQFPPMIESMESMRTIMLTMHSTMSGIFDQMNELS--------DNANT
Rv0402c|M.tuberculosis_H37Rv LLAQLDPTIATMQTVKDLAQTLTSAFSGLVTQMEDMT--------RNATV
MAB_1520c|M.abscessus_ATCC_199 MQKSFSGAVDSVKNMRATVAQLGAITDQLTHAVGETR-TMFSGLTEYLRA
MMAR_4975|M.marinum_M TAKSLTTADQSLAIMGADMAQLSATTAQLADAVHDAH-TAISDIIDYLRG
Mb1787|M.bovis_AF2122/97 ATSGVSGLPNALDGIGGQLAQVRESAAGVQELLNNVGAAPLRELPDYLRE
MAV_5284|M.avium_104 AATAMAGLPQNVDAMKSALVQARSATRDLLGLSDTLG-PQMRQLTDYLNE
. : : .
MSMEG_0225|M.smegmatis_MC2_155 MGEAFDKAKNDDSFYLPPETFDNPDFKRGMKMFLSPDGHAVRFIISHEGD
TH_3260|M.thermoresistible__bu MGEAFDQARNDDSFYLPPEAFDNPDFQRGLEQFLSPDGHAVRFIISHQGD
MUL_0757|M.ulcerans_Agy99 MGEAFDSSRNDDSFYLPPEVFNNPDFKRGLEQFLSPDGHAVRFIISHEGD
Mflv_2705|M.gilvum_PYR-GCK MGKAFDEAKNDDSFYLPPEVFENEDFKRAMESFFSPDGKTVRMLVSHRGD
Mvan_3833|M.vanbaalenii_PYR-1 MGKAFDAAKNDDSFYLPPEVFENEDFKRAMESFFSPDGKTVRMLIAHRGN
MLBr_02378|M.leprae_Br4923 MGKAFDTAKNDDSFYLPPEVFKNTDFKRAMKSFLSSDGHAARFIILHRGD
Rv0402c|M.tuberculosis_H37Rv MGRTFDAANNDDSFYLPPEAFQNPDFQRGLKLFLSPDGTCARFVITHRGD
MAB_1520c|M.abscessus_ATCC_199 MREDFRSSGEGG-YYLPQRAWQDPRFQRAAGLYFGPDGHSTRMLVFGDGK
MMAR_4975|M.marinum_M LRQGFQGSAEGT-FYLPQQAWNDPRFQRAANLYFSPDGHVTRLLVFGDGA
Mb1787|M.bovis_AF2122/97 LAAVSQSAPGVD-LYAARRILTDPNMRAVLDYFVSPNGHATRLLVYGDGS
MAV_5284|M.avium_104 ISTQFQGSAAAD-FYLPQRALTDPRYTAVLNHLISQTGRAAYLLVYGDGA
: : * . . : .. * . ::: *
MSMEG_0225|M.smegmatis_MC2_155 PMSPEGIQKIDDIKLAAKEAIKGTPLEGSKIYLGGTAATFKDMQEGANYD
TH_3260|M.thermoresistible__bu PMTPEGLAKIEPIKKAAVEAIKGTPLEGSRVYLGGTAAVFKDMSDGTKYD
MUL_0757|M.ulcerans_Agy99 PMSQAGINHIDKIKTAAKEAIKGTPLEGSTIYLGGTVAMFKDLSDGNTFD
Mflv_2705|M.gilvum_PYR-GCK PTTPEALARVEPIKIAAIEALKGTPLENAQIQLGGTAATFKDMSDGSRYD
Mvan_3833|M.vanbaalenii_PYR-1 PTTDEALQRVEPIKIAAIEALKGTPLENAQIQLGGTAATFKDMSDGSRYD
MLBr_02378|M.leprae_Br4923 PASVAGIASINAIRTAAEEALKGTPLEDTKIYLAGTAAVFKDIDEGANWD
Rv0402c|M.tuberculosis_H37Rv PASAEGISHIDPIMQAADEAVKGTPLQAASIYLAGTSSTYKDIHEGTLYD
MAB_1520c|M.abscessus_ATCC_199 VFGADGAHRSPQIMLAVSEATKEGTLAGSSVNLTGFGTGTAELRGYVSED
MMAR_4975|M.marinum_M VFGGDGANRSPQIVAAVKAATKEGVLAGSTVNIAGFGTATAELRGYVHHD
Mb1787|M.bovis_AF2122/97 EWGDDGAQRARAIVTAVAEETDEGTLRPTAVELTGVGPATRDLQDLVGSD
MAV_5284|M.avium_104 EWGADSAERAEQVRAAIKEATKEGTLTPVEVDLAGVGPVTADLQRFVADD
. : * . * : : * . :: *
MSMEG_0225|M.smegmatis_MC2_155 LIIAGIAALCLIFIIMLIITRAVVASAVIVGTVVISLGSAFGLSVLIWQH
TH_3260|M.thermoresistible__bu LIIAAIAAVCLIFIIMLILTRAVVAAAVIVGTVTLSLAASFGVSVLIWQY
MUL_0757|M.ulcerans_Agy99 LMIAGISALCLIFIIMLIITRSVVAAAVIVGTVVLSLGASFGLSVLIWQH
Mflv_2705|M.gilvum_PYR-GCK MMIAILSALCLVLVIMLVLTRSLVAAVVIVGTVALSLGASFGVSVLIWQH
Mvan_3833|M.vanbaalenii_PYR-1 LLIAVISALCLVLMIMLVLTRSLVAALVIVGTVTLSLGASFGISILIWQH
MLBr_02378|M.leprae_Br4923 LVIAGISSLCLIFIIMLIITRAFVAAAVIVGTVALSLGASFGLSVLLWQH
Rv0402c|M.tuberculosis_H37Rv VMIAVVASLCLIFIIMLGITRSVVASAVIVGTVALSLGSAFGLSVLIWQH
MAB_1520c|M.abscessus_ATCC_199 FLLLAAVALALVFLIVLVMLRSPVAAAVVIGTVIISYASALGVTTLIWQD
MMAR_4975|M.marinum_M FVLLAAAALALVFLIVLLMLRSPVAAAVVIGAVIVSYLSALGISTFIWHD
Mb1787|M.bovis_AF2122/97 LTLLAVITLAVIFAIAALLLRSPLAGLVVVGTIATSYICALGASVVIWKH
MAV_5284|M.avium_104 TRLLVGAALVLIFLIVTAMLRSPVAGLVVVGTVVTSYASAIGASVLIWQH
: :: ::: * : *: :*. *::*:: * .::* : .:*:
MSMEG_0225|M.smegmatis_MC2_155 LVGLELHWMVLAMAVIVLLAVGADYNLLLVSRIKEEIH------AGLDTG
TH_3260|M.thermoresistible__bu IVGLEMHWMVFPMALIILLAVGADYNLLVVARLREEIP------AGLNTG
MUL_0757|M.ulcerans_Agy99 VLGIELHWLVLAMAVIILLAVGADYNLLLVARLKEEIH------AGINTG
Mflv_2705|M.gilvum_PYR-GCK LLGVELHWMVLVMSIIALIAVGSDYNLLLVSRFKEEIG------AGIKTG
Mvan_3833|M.vanbaalenii_PYR-1 IVGIELHWMVLALSIIALIAVGSDYNLLLVSRFKEEIP------AGIKTG
MLBr_02378|M.leprae_Br4923 ILGIELHYLVLAMSVIVLLAVGSDYNLLLVSRFKQEIQ------AGLKTG
Rv0402c|M.tuberculosis_H37Rv ILHMPLHWLVLPMAIIVMLAVGSDYNLLLIARFQEEIG------AGLKTG
MAB_1520c|M.abscessus_ATCC_199 LLGRDLHWAVPSIALIALVAVGADYNLLLTMRMREEVFLH---GAGLRTG
MMAR_4975|M.marinum_M LLGKDLHWAVQSMAFISLVAVGADYNLLLTVRVREEVLAHPDRGVGLRTA
Mb1787|M.bovis_AF2122/97 ILGDNLHWSVLPIAFVLLISVGSAYNLLFALRIREE------SPAGPRTS
MAV_5284|M.avium_104 LLHQELHWAVAPIAFIALIAVGADYNLLLALRIKQE------AAAGLRTG
:: :*: * ::.: :::**: ****. *.::* .* *.
MSMEG_0225|M.smegmatis_MC2_155 MIRAMGGSGSVVTAAGLVFAFTMMSMAVSELAIIGQVGTTIGLGLLFDTL
TH_3260|M.thermoresistible__bu MIRAMGGSGSVVTAAGLVFGLTMMVMVVSDLTVMGQVGTTIGLGLLFDTF
MUL_0757|M.ulcerans_Agy99 IIRAMGGSGSVVTAAGLVFAFTMMSFAVSELTVMAQVGTTIGMGLLFDTL
Mflv_2705|M.gilvum_PYR-GCK IIRAIGGTGSVVSVAGVVFALTMASMVVSDLKVIAQVGTTIGLGLLFDTF
Mvan_3833|M.vanbaalenii_PYR-1 IIRAIGGTGSVVTVAGVVFALTMASMVVSDLRVMAQVGTTIGLGLLFDTF
MLBr_02378|M.leprae_Br4923 IIRSMGGTGKVVTNAGLVFAFTMASMVVSDLRVIGQVGTTIGLGLLFDTL
Rv0402c|M.tuberculosis_H37Rv MIRAMAGTGRVVTIAGLVFAFTMGSMVASDLRVVGQIGTTIMIGLLFDTL
MAB_1520c|M.abscessus_ATCC_199 MIRTFGGTGGVVTTAGIVFGITMFAMLSSDVLSIEQTGTTIGVGLMIDTL
MMAR_4975|M.marinum_M TIRAFGGAGGVVTTAGIVFAITMFAMASSDVLSIEQVGTTIGAGLIVDTL
Mb1787|M.bovis_AF2122/97 VIRAFAATGMVVTAAGIVFGTTMFALAASTSLSVAQIGVTVGMGLLLDAL
MAV_5284|M.avium_104 IIRAFGGTGGVVTVAGIIFGLTMLALLTSSVLSIAQIGTTIAVGLLLDTL
**::..:* **: **::*. ** : * : * *.*: **:.*::
MSMEG_0225|M.smegmatis_MC2_155 VIRSFMTPSIAALLGKWFWWPQMVRRRPKPSPWPKPIQREPADAVN----
TH_3260|M.thermoresistible__bu VVRSFMMPSIATLLGRWFWWPQFVRKRPVPQPWPSVPPRGPATTDRVSV-
MUL_0757|M.ulcerans_Agy99 IVRSFMTPSIAALLGKWFWWPQVVRQRPAPQPWPTPAPTPPPATTSV---
Mflv_2705|M.gilvum_PYR-GCK IVRAFMMPSIATLLGRWFWWPLVVRSRPLR-PRPQQQALGVGGQQG----
Mvan_3833|M.vanbaalenii_PYR-1 IVRAFMMPAIATLLGRWFWWPLVVRSRPLR-LPPRT--------------
MLBr_02378|M.leprae_Br4923 IVRSFMMPSIAALLGRWFWWPQQGRTRPLL-TVAAPVGLPPDRSLVYSD-
Rv0402c|M.tuberculosis_H37Rv VVRSYMTPALATLLGRWFWWPRRVDRLARQPQVLGPRRTTALSAERAALL
MAB_1520c|M.abscessus_ATCC_199 IVRTFVVPAIAGALGKWFWWSPVPLLRGLLF---RWSKARSPRTAGVLSY
MMAR_4975|M.marinum_M VVRIFAVPAIMGLLGRWFWWSPPPFLRASLAGPRRWGPWLRKRIASARRW
Mb1787|M.bovis_AF2122/97 VIRGFVLPALMVLLGRWLWWP----RRSVS-----NRQVPEPSPA-----
MAV_5284|M.avium_104 VVRAFIVPSIVALLGRWFWWPSPLPRRGVAR----VVKTVEPQPVSVATA
::* : *:: **:*:**.
MSMEG_0225|M.smegmatis_MC2_155 -------------------
TH_3260|M.thermoresistible__bu -------------------
MUL_0757|M.ulcerans_Agy99 -------------------
Mflv_2705|M.gilvum_PYR-GCK -------------------
Mvan_3833|M.vanbaalenii_PYR-1 -------------------
MLBr_02378|M.leprae_Br4923 -------------------
Rv0402c|M.tuberculosis_H37Rv Q------------------
MAB_1520c|M.abscessus_ATCC_199 LLT-----RPSRLERTGA-
MMAR_4975|M.marinum_M LSTSVLAASVRYLRRTASG
Mb1787|M.bovis_AF2122/97 -------------------
MAV_5284|M.avium_104 V------------------