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LPDRPGILGRLTGRYALLVVGLWVLAAAVANVAVPQLERVVDSHARSFMPPSAPSAVAAARAAQLFDQTP SNNFVYVVLERNQRLGAGDRQFYDALAAALGSDHRHVYAVTDLWSQPATAAGAQSTDGQAVSVMVRLAGM LGTAQARDSVNAVRATAQKLGPPAGLQVHVTGPGATIVDEFSAIDRQMLGITAATIGLILLLLLVVYRSP VAAAIPLISVGLALALARAVVAALGQANVVEVSLFSVALMAAMTLGAGTDYAIFLVGRYHEARRGGVAPA QALTVAYRSIAPVVIGSALTVSVALACLVFAHVGSFRSAGLPCAIGILATMVAALTLTPALMSLAVRRRY LEPRPSRTARRWRRVGTTVARWPGPILVAALGLTLLVALPLAGMRIGFNEPAATPSSTDSNRGYASAGRH FPENALLPDVIAIRADHDLRNPAGLIAIERITRHIMAVPGVRAVQSASRPDGKVPEQATLSYQAGVLGRQ FGDTVDSLTQRLARVSELDGALAQTQQAVDGLGNGLHGGSAGLADMSGAADDMRAGMDGLQRNVTTVSGY LDPLRDLVGRTPDCAANPICSMVDRVLAPVDSLVQTSAQLGSGAAKLTTGSNTAATAMAGLPQNVDAMKS ALVQARSATRDLLGLSDTLGPQMRQLTDYLNEISTQFQGSAAADFYLPQRALTDPRYTAVLNHLISQTGR AAYLLVYGDGAEWGADSAERAEQVRAAIKEATKEGTLTPVEVDLAGVGPVTADLQRFVADDTRLLVGAAL VLIFLIVTAMLRSPVAGLVVVGTVVTSYASAIGASVLIWQHLLHQELHWAVAPIAFIALIAVGADYNLLL ALRIKQEAAAGLRTGIIRAFGGTGGVVTVAGIIFGLTMLALLTSSVLSIAQIGTTIAVGLLLDTLVVRAF IVPSIVALLGRWFWWPSPLPRRGVARVVKTVEPQPVSVATAV
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_5284 | - | - | 100% (952) | membrane protein, MmpL family protein |
| M. avium 104 | MAV_3863 | - | e-169 | 37.18% (952) | MmpL4 protein |
| M. avium 104 | MAV_2510 | - | e-167 | 37.10% (938) | MmpL4 protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1787 | mmpL14 | 0.0 | 47.78% (946) | transmembrane transport protein MmpL14 |
| M. gilvum PYR-GCK | Mflv_3435 | - | 1e-169 | 36.42% (939) | transport protein |
| M. tuberculosis H37Rv | Rv0450c | mmpL4 | 1e-174 | 35.24% (945) | transmembrane transport protein MmpL4 |
| M. leprae Br4923 | MLBr_02378 | - | 1e-166 | 34.78% (946) | hypothetical protein MLBr_02378 |
| M. abscessus ATCC 19977 | MAB_1520c | - | 0.0 | 50.48% (947) | MmpL family membrane protein |
| M. marinum M | MMAR_4975 | - | 0.0 | 50.48% (935) | MmpL family transport protein |
| M. smegmatis MC2 155 | MSMEG_3584 | - | 1e-180 | 37.21% (938) | membrane protein, MmpL family protein |
| M. thermoresistible (build 8) | TH_3056 | - | 1e-167 | 35.36% (956) | PUTATIVE Mmp14a protein |
| M. ulcerans Agy99 | MUL_0757 | mmpL5 | 1e-165 | 35.80% (961) | transmembrane transport protein, MmpL5 |
| M. vanbaalenii PYR-1 | Mvan_3189 | - | 1e-169 | 36.21% (939) | transport protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3435|M.gilvum_PYR-GCK MSAPVSDARTDEFPAAHGPHRSFIPRMIRLFAVPIILGWIALIVVVNVTV
Mvan_3189|M.vanbaalenii_PYR-1 MSAPVSDARTDEFPAARQPHRPFIPRMIRLFAVPIILGWIALIVILNVTV
MUL_0757|M.ulcerans_Agy99 MTATTTDTPTDVVPPAEHPPRPFIPRMIRTFAVPLILGWVLLIAVLNSVV
Rv0450c|M.tuberculosis_H37Rv MSTKFAND----SNTNARPEKPFIARMIHAFAVPIILGWLAVCVVVTVFV
MLBr_02378|M.leprae_Br4923 MTVKCAND----LDTHTKP--PFVARMIHRFAVPIILVWLAIAVTVSVFI
TH_3056|M.thermoresistible__bu MSVLDRVG--------VEPRRPRVASFIRRYSVLIILGWVALTVLATVAV
MSMEG_3584|M.smegmatis_MC2_155 MPGQVGMS-------AHRAGRPFFARAVRVLALPIVAFWILVTIGTNIFV
MAV_5284|M.avium_104 ----------------MPDRPGILGRLTGRYALLVVGLWVLAAAVANVAV
Mb1787|M.bovis_AF2122/97 --------------------MTAIGRLIHRYAIWIVGVWALAAIIGNNFA
MAB_1520c|M.abscessus_ATCC_199 -------------------MWDAIARFSSRYAVLIIGLWVLLAGAGNLLV
MMAR_4975|M.marinum_M -------------------MWDRFTKITSRYAVLIVGLWIVGATVGNLLI
. :: :: * .
Mflv_3435|M.gilvum_PYR-GCK PQLETVGEAQAVSMSPNDAPSMISMKKVGELFEEGDSDSSVMIVFEGDQP
Mvan_3189|M.vanbaalenii_PYR-1 PQLEAVGEARAVSMSPNEAPSLISMKKVGELFREGDSDSSVMIVFEGDQP
MUL_0757|M.ulcerans_Agy99 PQLEVVGQMQAVSMSPDAAPSMISMKHIGKVFREGDSDSAAMIVLEGQEP
Rv0450c|M.tuberculosis_H37Rv PSLEAVGQERSVSLSPKDAPSFEAMGRIGMVFKEGDSDSFAMVIIEGNQP
MLBr_02378|M.leprae_Br4923 PSLEDVGQERSVSLSPKDAPSYIAMQKMGQVFNEGNSDSVIMIVLEGDKP
TH_3056|M.thermoresistible__bu PPLEAVEREKSLSLIPYDAPAFAAMHRMGELFDEPDSESIAIIVLEGQEP
MSMEG_3584|M.smegmatis_MC2_155 PQAEKVADELAGPMIPTYAPSQVALLQMGEKFGESDSTNLTMLVLEADRP
MAV_5284|M.avium_104 PQLERVVDSHARSFMPPSAPSAVAAARAAQLFDQTPSNNFVYVVLERNQR
Mb1787|M.bovis_AF2122/97 PPLEQVITAEDQPFSPAGTATSRAVERSAAAFSQAPGDNIGYLVLERNGV
MAB_1520c|M.abscessus_ATCC_199 PQVESTAHNHARGFLPQDAPVNAAGAVMGRQFQDGAGNNLNYLVLESDHK
MMAR_4975|M.marinum_M PQAESTARSHGRGFLPADAPVSVAGARMGEQFRDGNAGNINYLVLESDHR
* * . : * :. : . * : . . :::* :
Mflv_3435|M.gilvum_PYR-GCK LGDEAHAWYDELVDRLEADTAHVQSVQDFWSDPLTASGSQSNDGKAAYVQ
Mvan_3189|M.vanbaalenii_PYR-1 LGDEAHAWYDELVERLRADTKHVQSVQDFWSDPLTASGSQSNDGKAAYVQ
MUL_0757|M.ulcerans_Agy99 LGAAAHKFYDKMITKLRADTKHVQSVQDFWGDPLTATGAQSGDGKAAYVQ
Rv0450c|M.tuberculosis_H37Rv LGDAAHKYYDGLVAQLRADKKHVQSVQDLWGDPLTAAGVQSNDGKAAYVQ
MLBr_02378|M.leprae_Br4923 LGDDAHRFYDGLIRKLRADK-HVQSVQDFWGDPLTAPGAQSNDGKAAYVQ
TH_3056|M.thermoresistible__bu LGLEAHEYYDQLISQLREHPQYVQHIRDFWGDPLTAGAAQSDDGKAAFVQ
MSMEG_3584|M.smegmatis_MC2_155 LDDADHRFYDDLVRRLQSDPAHVQYVMDLWGEPITAAAVQSVDGKAAFVM
MAV_5284|M.avium_104 LGAGDRQFYDALAAALGSDHRHVYAVTDLWSQPATAAGAQSTDGQAVSVM
Mb1787|M.bovis_AF2122/97 LNDQDRAYYDALVVALRRDSRHVIEVVDWWGTPAIAEVARSDDHHAVTAA
MAB_1520c|M.abscessus_ATCC_199 LGPVEHQYHDRLLTTLRADTTHLDSAMDLWADPLTAEGALSPDGKAVYTM
MMAR_4975|M.marinum_M LGPAERAFYDKLLAKLRSDPTSLVSAMDLWSDPYTAKAAVSTDGEAEYTM
*. : ::* : * . : * *. * * * * .* .
Mflv_3435|M.gilvum_PYR-GCK VKLSGNQGEALANESVKAVQQTVSSLEPPPGVRAFVTGPAALAADQHIAG
Mvan_3189|M.vanbaalenii_PYR-1 VKLAGNQGESLANESVQAAQEIVRSLEPPPGVRAFVTGPAALAADQHIAS
MUL_0757|M.ulcerans_Agy99 VKLAGNQGESLANESVEAVKTIVDSLQAPPGVKVYVTGSAALVADQQLAG
Rv0450c|M.tuberculosis_H37Rv LSLAGNQGTPLANESVEAVRSIVESTPAPPGIKAYVTGPSALAADMHHSG
MLBr_02378|M.leprae_Br4923 LSLAGNQGELLAQESIDAVRKIVVQTPAPPGITAWVTGASALIADMHHSG
TH_3056|M.thermoresistible__bu VNLVGRFGQAKVNEAVRAVQEIVERTPAPEGVETFVTGPAALGADAGDSG
MSMEG_3584|M.smegmatis_MC2_155 LRLAGNTGKLEANESVDAVRDIVAADAPPPGLKVYVSGPAPLASDTLTIA
MAV_5284|M.avium_104 VRLAGMLGTAQARDSVNAVRATAQKLGPPAGLQVHVTGPGATIVDEFSAI
Mb1787|M.bovis_AF2122/97 LRFGGMVGTSQAGESITAARSIVTQLHPPDGLHVFVTGPGATIVDEFAAI
MAB_1520c|M.abscessus_ATCC_199 LRVNGELGAAKANDALAAVRKIVADQPAPPGTQAWVTGPGATIADELTAI
MMAR_4975|M.marinum_M LRLAGDLGAAQANAALDAVRRTVADQPTPPGLRAYVTGPGATVADEFGEI
: . * * . :: *.: . .* * . *:*... *
Mflv_3435|M.gilvum_PYR-GCK DRSMRLIEAATFTVIIVMLLLVYRSIVTVLITLVMVVMSLATARGVVAFL
Mvan_3189|M.vanbaalenii_PYR-1 DRSVRVIELVTFAVIIVMLLLVYRSIVTVLLTLVMVVLSLATARGVVAFL
MUL_0757|M.ulcerans_Agy99 DRSLQLIEMVTFTVIIVMLLLVYRSIITAAIMLTMVVLGLLATRGGVAFL
Rv0450c|M.tuberculosis_H37Rv DRSMARITMVTVAVIFIMLLLVYRSIITVVLLLITVGVELTAARGVVAVL
MLBr_02378|M.leprae_Br4923 DKSMIRITATSVIVILVTLLLVYRSFITVILLLFTVGIESAVARGVVALL
TH_3056|M.thermoresistible__bu TATVILITLVTVAVIFLMLLFFFRSFLTVIVLLLTVAVELQVARGLVAYL
MSMEG_3584|M.smegmatis_MC2_155 TASLKNITILTIILIVAMLLLVYRSVPSLLVPLPAVLIELLAAKGVVAVL
MAV_5284|M.avium_104 DRQMLGITAATIGLILLLLLVVYRSPVAAAIPLISVGLALALARAVVAAL
Mb1787|M.bovis_AF2122/97 DRQTQLITATTIVVLLILLLIVYRSAITATVPLLSVVVSLAVAKPIVSVL
MAB_1520c|M.abscessus_ATCC_199 DTQMLMITGVTVVLIAVLLFVVYRSVITAAIPLMTVGLGLAVARSIVAFL
MMAR_4975|M.marinum_M DRQMLLLTGVTVVLIALLLLAVYRSVITAAIPLVAVGLGLAVGRSIVSLL
: :. :: *: .:** : : * * : : *: *
Mflv_3435|M.gilvum_PYR-GCK GHHEIIGLSTFATNLLVTLAIAAATDYAIFLIGRYQEARTAGEDKETAYY
Mvan_3189|M.vanbaalenii_PYR-1 GWHEIIGLSLFATNLLVTLAIAAATDYAIFLIGRYQEARTNGEDKESAYY
MUL_0757|M.ulcerans_Agy99 GYHRIIGLSTFATNLLVVLAIAAATDYAIFLIGRYQEARGLGQDRESAYY
Rv0450c|M.tuberculosis_H37Rv GHSGAIGLTTFAVSLLTSLAIAAGTDYGIFIIGRYQEARQAGEDKEAAYY
MLBr_02378|M.leprae_Br4923 GHTGLIGLSTFAVNLLTSLAIAAGTDYGIFITGRYQEARQANENKEAAFY
TH_3056|M.thermoresistible__bu GLQGWVGLTTYVVNLLVSVGIAAGTDYGIFFFGRYQEAREAGEDRDSAYF
MSMEG_3584|M.smegmatis_MC2_155 GHLGVIPLSSFAVNLLVALTLGAGTDYGIFMLGRYQEARRAGESREEAYF
MAV_5284|M.avium_104 GQANVVEVSLFSVALMAAMTLGAGTDYAIFLVGRYHEARRGGVAPAQALT
Mb1787|M.bovis_AF2122/97 VDRDFIGISLFSLGLSVAVVVGAGTGFAMFLIGRYHERRRQHIAPAAALA
MAB_1520c|M.abscessus_ATCC_199 GERDLIEVSIFSVSLLAALVLGAATDYGIFLLGRYHEQRRSGVDHEQALV
MMAR_4975|M.marinum_M GQHNLLEVSVFSVALLGAMVLGGATDYAIFLLGRYHEARRDGVEHEQALL
: :: : * : :...*.:.:*: ***:* * *
Mflv_3435|M.gilvum_PYR-GCK TMFHGTAHVVLGSGLTIAGAT---FCLSFTRLPYFQTMGVPLAIGMFVVV
Mvan_3189|M.vanbaalenii_PYR-1 TMFHGTAHVVLGSGLTIAGAT---YCLSFTRLPYFQTLGVPLAIGMFVVV
MUL_0757|M.ulcerans_Agy99 TMFGGTAHVVLGSGLTIAGAT---FCLSFTRLPYFQTLGVPLAIGMVIVV
Rv0450c|M.tuberculosis_H37Rv TMYRGTAHVILGSGLTIAGAT---FCLSFARMPYFQTLGIPCAVGMLVAV
MLBr_02378|M.leprae_Br4923 TMYRGTFHVILGSGLTISGAT---FCLSFARMPYFQTLGVPCAVGMLIAV
TH_3056|M.thermoresistible__bu TTYRSVAKVVLASGLTIAGAI---ACLSFTRLPHFQPLGIPGAVGLLVAV
MSMEG_3584|M.smegmatis_MC2_155 TAYRSVAPIIIGSGLTIAGAC---FCLSLARLDYFHTMGPAVAVSMLCTI
MAV_5284|M.avium_104 VAYRSIAPVVIGSALTVSVAL---ACLVFAHVGSFRSAGLPCAIGILATM
Mb1787|M.bovis_AF2122/97 DAYRGVAPAIAGATFIVVTSLGAVGWLSLARIGMFATTGILCSIGVLAVG
MAB_1520c|M.abscessus_ATCC_199 IANRSVAPVIAASGLTIAAAL---SCLLFAQVGMLRSAGLPCAIGILTGM
MMAR_4975|M.marinum_M AANRNVMPVVLASALTLAAAL---SCLTFADVGLLRSAGLPCAVGVLIGM
. : .: : : : * :: : : . * ::.:.
Mflv_3435|M.gilvum_PYR-GCK MAGVVLMVACISVATRFGKLLEPKRAMRI-RGWRKIGAAIVRWPGPILVA
Mvan_3189|M.vanbaalenii_PYR-1 MAGVILMVAMISVATRFGKLLEPKRAMRI-RGWRKIGAAVVRWPGPILVA
MUL_0757|M.ulcerans_Agy99 ATALTLGPALIAVMSRFGKLLEPKRMARV-RGWRKIGAAIVRWPGPILIG
Rv0450c|M.tuberculosis_H37Rv AVALTLGPAVLHVGSRFG-LFDPKRLLKV-RGWRRVGTVVVRWPLPVLVA
MLBr_02378|M.leprae_Br4923 AVALTLGPAVLTVGSRFG-LFEPKRLIKV-RGWRRIGTVVVRWPLPILIT
TH_3056|M.thermoresistible__bu AVALTLVPATIALGSRFG-LFEPKRRVMT-HRWRRIGTAVVRWPVPILTA
MSMEG_3584|M.smegmatis_MC2_155 AAALTLAPALLTLGSRRG-LFDPRRLNSG-RLYRHIATSVVRWPKPVFVA
MAV_5284|M.avium_104 VAALTLTPALMSLAVRRRYLEP--RPSRTARRWRRVGTTVARWPGPILVA
Mb1787|M.bovis_AF2122/97 LAALTLTPALVALASRANLLKPP-QHKRIQRQFRRLGTHVARWPAPILVA
MAB_1520c|M.abscessus_ATCC_199 VASLTLLPALIGLAGRRGLAQPRPLRGQPGRRWRRVGAMVSRWPGPVLAG
MMAR_4975|M.marinum_M LASLTLLPALLDLAGRRGLAQPRTVNRPIHRRWRRIGTMVARWPGPVLVA
..: * * : : * : :*::.: : *** *::
Mflv_3435|M.gilvum_PYR-GCK TMAITLVGLLALPGYKTNYNDRDYLPADLPANQGYAVADEHFDQARMN-P
Mvan_3189|M.vanbaalenii_PYR-1 TLAITLVGLLALPGYKTNYNDRTYLPADLPANEGYAVADRHFDQARMN-P
MUL_0757|M.ulcerans_Agy99 AVALALVGLLTLPGYKTNYNDRNYLPADLPANEGYSAAERHFSQARMN-P
Rv0450c|M.tuberculosis_H37Rv TCAIALVGLLALPGYKTSYNDRDYLPDFIPANQGYAAADRHFSQARMK-P
MLBr_02378|M.leprae_Br4923 TCAIAMVGLLALPGYRTNYKDRAYLPASIPANQGFAAADRHFPQARMK-P
TH_3056|M.thermoresistible__bu AVALSLVGLLTLPGYNPSYSDQEFIPDDIPASEGYKAAARHFPASAMSVP
MSMEG_3584|M.smegmatis_MC2_155 SAVVVLVGAVFVPTYQVGYDDRAYQPADAPAKLGFEAADRHFPQSKLM-S
MAV_5284|M.avium_104 ALGLTLLVALPLAGMRIGFNEPAATPSSTDSNRGYASAGRHFPENALL-P
Mb1787|M.bovis_AF2122/97 SGVFVLIMMIALPRVPIGWDEAAATPSAAESNRGYRAADRHFAPNQLL-P
MAB_1520c|M.abscessus_ATCC_199 SLLVLVVCALPVAGLRLGFDELAAQPLSTHANRGYQAMDRHFPPNRLL-P
MMAR_4975|M.marinum_M AALVLLICTLPITGLTLGFNEPAAEPDSTLANRGYQATDRHFPPNQLL-P
: . :: : :. .:.: * :. *: .** : .
Mflv_3435|M.gilvum_PYR-GCK ELLMIESDHDLRNSADFLVIDKIAKALFRVEGIARVQAITRPDGKPIKHT
Mvan_3189|M.vanbaalenii_PYR-1 ELLMIESDHDLRNSADFLVIDKIAKAIFKVEGIARVQAITRPDGKPIKHT
MUL_0757|M.ulcerans_Agy99 EVLMVESDHDMRNSSDFLVINKIAKAIFGVEGISRVQAITRPDGKPIEHT
Rv0450c|M.tuberculosis_H37Rv EILMIESDHDMRNPADFLVLDKLAKGIFRVPGISRVQAITRPEGTTMDHT
MLBr_02378|M.leprae_Br4923 EILMIESDHDMRNPADFLILDKLARGIFRVPGISRVQAITRPDGTAMDHT
TH_3056|M.thermoresistible__bu DVVLIEADRDMRNPADLLVLNKVAKKIFEVPGVANVQSVTRPEGRQIEHT
MSMEG_3584|M.smegmatis_MC2_155 ELLMVESDHDMRNSADFISLDRAAKSLIRLPGVAMVQSITRPLGRPLEHA
MAV_5284|M.avium_104 DVIAIRADHDLRNPAGLIAIERITRHIMAVPGVRAVQSASRPDGKVPEQA
Mb1787|M.bovis_AF2122/97 TQVMIETDHDIRNPAGLTAIERITAAIMAIGGVRMVQSASHPNGMVSKQA
MAB_1520c|M.abscessus_ATCC_199 EIVSIESDHDLRTPAGVIAVERVTKGLMEIPGIRMVQSASRPAGTIPEQA
MMAR_4975|M.marinum_M ETVSIETDHDLRNPTGVIAIERVTRQLMTIPGIRMVQSASRPAGSVPDEA
: :.:*:*:*..:.. ::: : :: : *: **: ::* * ..:
Mflv_3435|M.gilvum_PYR-GCK SIPFQMSMQGTTQRLNEKYMQDRMADMLVQADEMANTIKTMEKMSGLTAQ
Mvan_3189|M.vanbaalenii_PYR-1 SIPFQMSMQGTTQRLNEKYMQDRMADMLVQADEMANTIATMEKMSNLTAQ
MUL_0757|M.ulcerans_Agy99 SIPFLISMQGTSQKLTEKYNQDLTTSMLQQVNDIQTNIDQMERMHDLTQQ
Rv0450c|M.tuberculosis_H37Rv SIPFQISMQNAGQLQTIKYQRDRANDMLKQADEMATTIAVLTRMHSLMAE
MLBr_02378|M.leprae_Br4923 SIPFQISMQNAGQVQTMKYQKDRMNDLLRQAENMAETIASMRRMHQLMAL
TH_3056|M.thermoresistible__bu TIPFMLSMSQASQRLALPFQRARMDDMLKQADELTETIALMRRMQSLMEK
MSMEG_3584|M.smegmatis_MC2_155 TIPYLFTMQGSTSGQQLPFDQQLNENTDRQADIQAHSLQVIQQVISITTQ
MAV_5284|M.avium_104 TLSYQAGVLGRQFGDTVDSLTQRLARVSELDGALAQTQQAVDGLGNGLHG
Mb1787|M.bovis_AF2122/97 ALTASAGNLGDQLDEFSDQLTSRQATFTNLEAAVRDVVSALDLVQAGIRQ
MAB_1520c|M.abscessus_ATCC_199 ALTEQAGIIADQLDDGTAQMSQRLGAVDKLSATLSQFSGAIAQLQKGLAG
MMAR_4975|M.marinum_M TLANQAGAIGDRLDQRIAQLDHRFSSINVIAPTLSRFSAAISRLQEQLSG
::. : :
Mflv_3435|M.gilvum_PYR-GCK MADITHSMVTKMEGMVVDIEDLRDSIANFDDFFRPIRNYFYWEPHCYNIP
Mvan_3189|M.vanbaalenii_PYR-1 MADITHSMVSKMENMLTDIEDLRDSIANFDDFFRPIRNYFYWEPHCYNIP
MUL_0757|M.ulcerans_Agy99 MADVTHQMVIQMKGMVVDVEELRNHIADFDDFFRPIRSYFYWEKHCFDIP
Rv0450c|M.tuberculosis_H37Rv MASTTHRMVGDTEEMKEITEELRDHVADFDDFWRPIRSYFYWEKHCYGIP
MLBr_02378|M.leprae_Br4923 LTENTHHILNDTVEMQKTTSKLRDEIANFDDFWRPIRSYFYWERHCFNIP
TH_3056|M.thermoresistible__bu MVATTHSMVGTTHELLDTTRDLRDHIADFDDFFRPIRNYFHWEPHCYNIP
MSMEG_3584|M.smegmatis_MC2_155 MSDELHATTVTFENLKEVTDEVNEGISDLDDFLRPLKNYFYWEPHCFDIP
MAV_5284|M.avium_104 GSAGLADMSGAADDMRAGMDGLQRNVTTVSGYLDPLRDLVGRTPDCAANP
Mb1787|M.bovis_AF2122/97 DGYGLGQVSLAVRLMQQAITKLQGSAGDVFDIFDPLRRFVAAIPECRANP
MAB_1520c|M.abscessus_ATCC_199 GVNGLGELNGGIGDMHSGMKALQDNVSQVSGYMEPLRNFTNGNPNCANDG
MMAR_4975|M.marinum_M SANGLGRVNSGIDAMDSGLVQLHDTAAQVSGYLNPLRDYTNSVANCPSDP
: :. . . *:: .*
Mflv_3435|M.gilvum_PYR-GCK VCWALRSVFDTLDGINIMTDDFKAIIPDMKRLDTLMPQMVALMPEMIETM
Mvan_3189|M.vanbaalenii_PYR-1 VCWALRSVFDTLDGINVMTDDFREILPDMKRLDSLMPQMVALMPEMIETM
MUL_0757|M.ulcerans_Agy99 VCWSLRSVFDTLDGVDLMTEDINNLLPLMERLDTLMPQMTAMMPEMIQTM
Rv0450c|M.tuberculosis_H37Rv ICWSFRSIFDALDGIDKLSEQIGVLLGDLREMDRLMPQMVAQIPPQIEAM
MLBr_02378|M.leprae_Br4923 ICWSFRSIFDALDGVDQIDERLNSIVGDIKNMDLLMPQMLEQFPPMIESM
TH_3056|M.thermoresistible__bu ICWSIRSIFDALDGINEMTEKMEELVEDMDRLDALMPQMLVQFPQMIETM
MSMEG_3584|M.smegmatis_MC2_155 VCFAIRSLFDSLDGIDRLDEQIGNAVESFEAIDRLLPQMITQLEQMKIAG
MAV_5284|M.avium_104 ICSMVDRVLAPVDSLVQTSAQLGSGAAKLTTGSN---TAATAMAGLPQNV
Mb1787|M.bovis_AF2122/97 VCSVAQEVVQWANTVTESCAKLADAAGQLARGIADVASATSGVSGLPNAL
MAB_1520c|M.abscessus_ATCC_199 ICSLVLKAVEPMDSVVAATASLTASTTKFGAGAQ---GMQKSFSGAVDSV
MMAR_4975|M.marinum_M VCALVLKVIDPADSIVVETNSLAKGTSQLGAGMS---DTAKSLTTADQSL
:* . : : : : .
Mflv_3435|M.gilvum_PYR-GCK KTMRTMMLTMYQSQKGQQDQMAAMS--------EDADAMGEAFDDSMNDD
Mvan_3189|M.vanbaalenii_PYR-1 KTMRTMMLTMYQSQKGQQDQMAAMS--------EDADAMGEAFDDSMNDD
MUL_0757|M.ulcerans_Agy99 KSMKAQMLSMHSTQQGLQDQMAAMQ--------EDSSAMGEAFDSSRNDD
Rv0450c|M.tuberculosis_H37Rv ENMRTMILTMHSTMTGIFDQMLEMS--------DNATAMGKAFDAAKNDD
MLBr_02378|M.leprae_Br4923 ESMRTIMLTMHSTMSGIFDQMNELS--------DNANTMGKAFDTAKNDD
TH_3056|M.thermoresistible__bu ESSRTMILTMHATMSGIFDQMESSS--------ENATAMGKAFDASHNDD
MSMEG_3584|M.smegmatis_MC2_155 KATLSLLQNNYGSAHLQSTQTDQTY--------DDLINVGNDFDAARSDD
MAV_5284|M.avium_104 DAMKSALVQARSATRDLLGLSDTLG-PQMRQLTDYLNEISTQFQGSAAAD
Mb1787|M.bovis_AF2122/97 DGIGGQLAQVRESAAGVQELLNNVGAAPLRELPDYLRELAAVSQSAPGVD
MAB_1520c|M.abscessus_ATCC_199 KNMRATVAQLGAITDQLTHAVGETR-TMFSGLTEYLRAMREDFRSSGEGG
MMAR_4975|M.marinum_M AIMGADMAQLSATTAQLADAVHDAH-TAISDIIDYLRGLRQGFQGSAEGT
: : : :
Mflv_3435|M.gilvum_PYR-GCK SFYLPPEIFENADFQRGLEQFLSPDGHAVRFIISHEGDPLSPEGVAKIDK
Mvan_3189|M.vanbaalenii_PYR-1 SFYLPPEIFENKDFQRGLEQFLSPDGHAVRFIISHEGDPLSPEGVAKIDK
MUL_0757|M.ulcerans_Agy99 SFYLPPEVFNNPDFKRGLEQFLSPDGHAVRFIISHEGDPMSQAGINHIDK
Rv0450c|M.tuberculosis_H37Rv SFYLPPEVFKNKDFQRAMKSFLSSDGHAARFIILHRGDPQSPEGIKSIDA
MLBr_02378|M.leprae_Br4923 SFYLPPEVFKNTDFKRAMKSFLSSDGHAARFIILHRGDPASVAGIASINA
TH_3056|M.thermoresistible__bu SFYLPPEALENKDFQRVMEIFLSPDGKAARMLVTQRGDPATPEGMALVEP
MSMEG_3584|M.smegmatis_MC2_155 FFYIPHEAFDNDDVKTGMKLLMSPDGKAARFIITHEGNAMAQEGIEHVEQ
MAV_5284|M.avium_104 -FYLPQRALTDPRYTAVLNHLISQTGRAAYLLVYGDGAEWGADSAERAEQ
Mb1787|M.bovis_AF2122/97 -LYAARRILTDPNMRAVLDYFVSPNGHATRLLVYGDGSEWGDDGAQRARA
MAB_1520c|M.abscessus_ATCC_199 -YYLPQRAWQDPRFQRAAGLYFGPDGHSTRMLVFGDGKVFGADGAHRSPQ
MMAR_4975|M.marinum_M -FYLPQQAWNDPRFQRAANLYFSPDGHVTRLLVFGDGAVFGGDGANRSPQ
* . . : .. *: . ::: * .
Mflv_3435|M.gilvum_PYR-GCK IKTAAKEAVKGTPLEGSKIYLGGTAAVFKDMQDGNNYDLLIAGIAALGLI
Mvan_3189|M.vanbaalenii_PYR-1 IKTAAKEAIKGTPLEGSKIYLGGTAATFKDMQDGNNYDLLIAGISALGLI
MUL_0757|M.ulcerans_Agy99 IKTAAKEAIKGTPLEGSTIYLGGTVAMFKDLSDGNTFDLMIAGISALCLI
Rv0450c|M.tuberculosis_H37Rv IRTAAEESLKGTPLEDAKIYLAGTAAVFHDISEGAQWDLLIAAISSLCLI
MLBr_02378|M.leprae_Br4923 IRTAAEEALKGTPLEDTKIYLAGTAAVFKDIDEGANWDLVIAGISSLCLI
TH_3056|M.thermoresistible__bu IYIAAEEALKGTPLESSRIYLAGSAAGVKDLVEGAKYDLMIAAISAVCLI
MSMEG_3584|M.smegmatis_MC2_155 IPDAIKMALKETSLAGAKVYLGGAASSTKDIQDYAASDLLIVAIAAFVLI
MAV_5284|M.avium_104 VRAAIKEATKEGTLTPVEVDLAGVGPVTADLQRFVADDTRLLVGAALVLI
Mb1787|M.bovis_AF2122/97 IVTAVAEETDEGTLRPTAVELTGVGPATRDLQDLVGSDLTLLAVITLAVI
MAB_1520c|M.abscessus_ATCC_199 IMLAVSEATKEGTLAGSSVNLTGFGTGTAELRGYVSEDFLLLAAVALALV
MMAR_4975|M.marinum_M IVAAVKAATKEGVLAGSTVNIAGFGTATAELRGYVHHDFVLLAAAALALV
: * . * : : * . :: * : :. ::
Mflv_3435|M.gilvum_PYR-GCK FIIMLILTRAVVAAAVIVGTVVLSLAASFGLSVLFWQHILGQPLHWMVLA
Mvan_3189|M.vanbaalenii_PYR-1 FIIMLILTRAIVAAAVIVGTVVLSLAASFGLSVLFWQHILGTELHWMVLA
MUL_0757|M.ulcerans_Agy99 FIIMLIITRSVVAAAVIVGTVVLSLGASFGLSVLIWQHVLGIELHWLVLA
Rv0450c|M.tuberculosis_H37Rv FIIMLIITRAFIAAAVIVGTVALSLGASFGLSVLLWQHILAIHLHWLVLA
MLBr_02378|M.leprae_Br4923 FIIMLIITRAFVAAAVIVGTVALSLGASFGLSVLLWQHILGIELHYLVLA
TH_3056|M.thermoresistible__bu FMIMVFMTRSVIAALVIVGTVVLSLGASFGMSVLLWQHLLGIQLHWVVLA
MSMEG_3584|M.smegmatis_MC2_155 FLIMLYLTRSLVAAMVIPGTVAFSFAGAFGLSVLVWQHLIGLPLHWLVLP
MAV_5284|M.avium_104 FLIVTAMLRSPVAGLVVVGTVVTSYASAIGASVLIWQHLLHQELHWAVAP
Mb1787|M.bovis_AF2122/97 FAIAALLLRSPLAGLVVVGTIATSYICALGASVVIWKHILGDNLHWSVLP
MAB_1520c|M.abscessus_ATCC_199 FLIVLVMLRSPVAAAVVIGTVIISYASALGVTTLIWQDLLGRDLHWAVPS
MMAR_4975|M.marinum_M FLIVLLMLRSPVAAAVVIGAVIVSYLSALGISTFIWHDLLGKDLHWAVQS
* * : *: :*. *: *:: * ::* :...*:.:: **: * .
Mflv_3435|M.gilvum_PYR-GCK MAVIILLAVGADYNLLLVSRLKEEI------HAGIGTGIIRAMGGSGSVV
Mvan_3189|M.vanbaalenii_PYR-1 MAVIVLLAVGADYNLLLVSRLKEEI------HAGIGTGIIRAMGGSGSVV
MUL_0757|M.ulcerans_Agy99 MAVIILLAVGADYNLLLVARLKEEI------HAGINTGIIRAMGGSGSVV
Rv0450c|M.tuberculosis_H37Rv MSVIVLLAVGSDYNLLLVSRFKQEI------GAGLKTGIIRSMGGTGKVV
MLBr_02378|M.leprae_Br4923 MSVIVLLAVGSDYNLLLVSRFKQEI------QAGLKTGIIRSMGGTGKVV
TH_3056|M.thermoresistible__bu MSVIVLLAVGSDYNLMLVSRMKEEI------GAGLNTGIIRAMGGTGRVV
MSMEG_3584|M.smegmatis_MC2_155 LAFIILVAVGSDYNLLLISRVKEES------GAGLNTALIRALGSTGAVV
MAV_5284|M.avium_104 IAFIALIAVGADYNLLLALRIKQE------AAAGLRTGIIRAFGGTGGVV
Mb1787|M.bovis_AF2122/97 IAFVLLISVGSAYNLLFALRIREE------SPAGPRTSVIRAFAATGMVV
MAB_1520c|M.abscessus_ATCC_199 IALIALVAVGADYNLLLTMRMREEVFLH---GAGLRTGMIRTFGGTGGVV
MMAR_4975|M.marinum_M MAFISLVAVGADYNLLLTVRVREEVLAHPDRGVGLRTATIRAFGGAGGVV
::.: *::**: ***:: *.::* .* *. **::..:* **
Mflv_3435|M.gilvum_PYR-GCK TAAGLVFALTMMSMSVSELTVIGQVGTTIGLGLLFDTLVIRAFMTPSIAA
Mvan_3189|M.vanbaalenii_PYR-1 TAAGLVFALTMMSMAVSELTVIGQVGTTIGLGLLFDTLVIRAFMTPSIAA
MUL_0757|M.ulcerans_Agy99 TAAGLVFAFTMMSFAVSELTVMAQVGTTIGMGLLFDTLIVRSFMTPSIAA
Rv0450c|M.tuberculosis_H37Rv TNAGLVFAVTMASMAVSDLRVIGQVGTTIGLGLLFDTLIVRSFMTPSIAA
MLBr_02378|M.leprae_Br4923 TNAGLVFAFTMASMVVSDLRVIGQVGTTIGLGLLFDTLIVRSFMMPSIAA
TH_3056|M.thermoresistible__bu TMAGLVFAATMASMIVSDLLMIGQVGTTIALGLLFDTMVVRAFMTPSVAA
MSMEG_3584|M.smegmatis_MC2_155 TSAGLVFAFTMLSMLASNLAAVGQLGSTVCIGLLLDTMIVRSLVVPCLLR
MAV_5284|M.avium_104 TVAGIIFGLTMLALLTSSVLSIAQIGTTIAVGLLLDTLVVRAFIVPSIVA
Mb1787|M.bovis_AF2122/97 TAAGIVFGTTMFALAASTSLSVAQIGVTVGMGLLLDALVIRGFVLPALMV
MAB_1520c|M.abscessus_ATCC_199 TTAGIVFGITMFAMLSSDVLSIEQTGTTIGVGLMIDTLIVRTFVVPAIAG
MMAR_4975|M.marinum_M TTAGIVFAITMFAMASSDVLSIEQVGTTIGAGLIVDTLVVRIFAVPAIMG
* **::*. ** :: * : * * *: **:.*::::* : *.:
Mflv_3435|M.gilvum_PYR-GCK LLGPWFWWPQRVRTRPVPAPWPRSGGLQSDPSEGVRA-------------
Mvan_3189|M.vanbaalenii_PYR-1 LLGPWFWWPQRVRTRPVPAPWPRPGGLQSDPSEGVKV-------------
MUL_0757|M.ulcerans_Agy99 LLGKWFWWPQVVRQRPAPQPWPTPAPTPPPATTSV---------------
Rv0450c|M.tuberculosis_H37Rv LLGRWFWWPLRVRSRPARTPTVPSETQPAGRPLAMSSDRLG---------
MLBr_02378|M.leprae_Br4923 LLGRWFWWPQQGRTRPLLTVAAPVGLPPD-RSLVYSD-------------
TH_3056|M.thermoresistible__bu ILGRWFWWPQRVRTRPASAMLRPVGPRPLVRSLLLRD-------------
MSMEG_3584|M.smegmatis_MC2_155 LLGPWFWWPTFIRQRPLRTPDRFARPGPSRRIMTDR--------------
MAV_5284|M.avium_104 LLGRWFWWPSPLPRRGVAR----VVKTVEPQPVSVATAV-----------
Mb1787|M.bovis_AF2122/97 LLGRWLWWP----RRSVS-----NRQVPEPSPA-----------------
MAB_1520c|M.abscessus_ATCC_199 ALGKWFWWSPVPLLRGLLF---RWSKARSPRTAGVLSYLLT-----RPSR
MMAR_4975|M.marinum_M LLGRWFWWSPPPFLRASLAGPRRWGPWLRKRIASARRWLSTSVLAASVRY
** *:**. *
Mflv_3435|M.gilvum_PYR-GCK -------
Mvan_3189|M.vanbaalenii_PYR-1 -------
MUL_0757|M.ulcerans_Agy99 -------
Rv0450c|M.tuberculosis_H37Rv -------
MLBr_02378|M.leprae_Br4923 -------
TH_3056|M.thermoresistible__bu -------
MSMEG_3584|M.smegmatis_MC2_155 -------
MAV_5284|M.avium_104 -------
Mb1787|M.bovis_AF2122/97 -------
MAB_1520c|M.abscessus_ATCC_199 LERTGA-
MMAR_4975|M.marinum_M LRRTASG