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VWDRFTKITSRYAVLIVGLWIVGATVGNLLIPQAESTARSHGRGFLPADAPVSVAGARMGEQFRDGNAGN INYLVLESDHRLGPAERAFYDKLLAKLRSDPTSLVSAMDLWSDPYTAKAAVSTDGEAEYTMLRLAGDLGA AQANAALDAVRRTVADQPTPPGLRAYVTGPGATVADEFGEIDRQMLLLTGVTVVLIALLLLAVYRSVITA AIPLVAVGLGLAVGRSIVSLLGQHNLLEVSVFSVALLGAMVLGGATDYAIFLLGRYHEARRDGVEHEQAL LAANRNVMPVVLASALTLAAALSCLTFADVGLLRSAGLPCAVGVLIGMLASLTLLPALLDLAGRRGLAQP RTVNRPIHRRWRRIGTMVARWPGPVLVAAALVLLICTLPITGLTLGFNEPAAEPDSTLANRGYQATDRHF PPNQLLPETVSIETDHDLRNPTGVIAIERVTRQLMTIPGIRMVQSASRPAGSVPDEATLANQAGAIGDRL DQRIAQLDHRFSSINVIAPTLSRFSAAISRLQEQLSGSANGLGRVNSGIDAMDSGLVQLHDTAAQVSGYL NPLRDYTNSVANCPSDPVCALVLKVIDPADSIVVETNSLAKGTSQLGAGMSDTAKSLTTADQSLAIMGAD MAQLSATTAQLADAVHDAHTAISDIIDYLRGLRQGFQGSAEGTFYLPQQAWNDPRFQRAANLYFSPDGHV TRLLVFGDGAVFGGDGANRSPQIVAAVKAATKEGVLAGSTVNIAGFGTATAELRGYVHHDFVLLAAAALA LVFLIVLLMLRSPVAAAVVIGAVIVSYLSALGISTFIWHDLLGKDLHWAVQSMAFISLVAVGADYNLLLT VRVREEVLAHPDRGVGLRTATIRAFGGAGGVVTTAGIVFAITMFAMASSDVLSIEQVGTTIGAGLIVDTL VVRIFAVPAIMGLLGRWFWWSPPPFLRASLAGPRRWGPWLRKRIASARRWLSTSVLAASVRYLRRTASG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_4975 | - | - | 100% (979) | MmpL family transport protein |
| M. marinum M | MMAR_1722 | mmpL1_1 | e-170 | 36.66% (941) | transmembrane transport protein MmpL1_1 |
| M. marinum M | MMAR_0704 | mmpL1 | e-167 | 36.05% (932) | transmembrane transport protein MmpL1 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1787 | mmpL14 | 0.0 | 40.92% (931) | transmembrane transport protein MmpL14 |
| M. gilvum PYR-GCK | Mflv_3435 | - | 1e-164 | 35.52% (929) | transport protein |
| M. tuberculosis H37Rv | Rv0402c | mmpL1 | 1e-170 | 37.28% (920) | transmembrane transport protein MmpL1 |
| M. leprae Br4923 | MLBr_02378 | - | 1e-162 | 34.70% (928) | hypothetical protein MLBr_02378 |
| M. abscessus ATCC 19977 | MAB_1520c | - | 0.0 | 65.32% (963) | MmpL family membrane protein |
| M. avium 104 | MAV_5284 | - | 0.0 | 50.48% (935) | membrane protein, MmpL family protein |
| M. smegmatis MC2 155 | MSMEG_3584 | - | 1e-173 | 36.92% (975) | membrane protein, MmpL family protein |
| M. thermoresistible (build 8) | TH_3260 | - | 1e-164 | 35.65% (937) | PUTATIVE MmpL4 protein |
| M. ulcerans Agy99 | MUL_0757 | mmpL5 | 1e-162 | 35.44% (948) | transmembrane transport protein, MmpL5 |
| M. vanbaalenii PYR-1 | Mvan_3189 | - | 1e-165 | 35.43% (923) | transport protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3435|M.gilvum_PYR-GCK MSAPVSDARTDEFPAAHGPHRS------FIPRMIRLFAVPIILGWIALIV
Mvan_3189|M.vanbaalenii_PYR-1 MSAPVSDARTDEFPAARQPHRP------FIPRMIRLFAVPIILGWIALIV
MUL_0757|M.ulcerans_Agy99 MTATTTDTPTDVVPPAEHPPRP------FIPRMIRTFAVPLILGWVLLIA
TH_3260|M.thermoresistible__bu MTANPGHVRTDEAPTDRLDIKVSTHGPSFISTWIRRLSLPIIVGWIALIA
MLBr_02378|M.leprae_Br4923 MTVKCANDLDTHTKPP------------FVARMIHRFAVPIILVWLAIAV
Rv0402c|M.tuberculosis_H37Rv ---MRSQRLAGHLSAA--------------ARTIHALSLPIILFWVALTI
MSMEG_3584|M.smegmatis_MC2_155 ---MPGQVGMSAHRAGRP----------FFARAVRVLALPIVAFWILVTI
MMAR_4975|M.marinum_M -------------------------MWDRFTKITSRYAVLIVGLWIVGAT
MAB_1520c|M.abscessus_ATCC_199 -------------------------MWDAIARFSSRYAVLIIGLWVLLAG
Mb1787|M.bovis_AF2122/97 --------------------------MTAIGRLIHRYAIWIVGVWALAAI
MAV_5284|M.avium_104 ----------------------MPDRPGILGRLTGRYALLVVGLWVLAAA
:: :: *
Mflv_3435|M.gilvum_PYR-GCK VVNVTVPQLETVGEAQAVSMSPNDAPSMISMKKVGELFEEGDSDSSVMIV
Mvan_3189|M.vanbaalenii_PYR-1 ILNVTVPQLEAVGEARAVSMSPNEAPSLISMKKVGELFREGDSDSSVMIV
MUL_0757|M.ulcerans_Agy99 VLNSVVPQLEVVGQMQAVSMSPDAAPSMISMKHIGKVFREGDSDSAAMIV
TH_3260|M.thermoresistible__bu LLNITVPQLEVVGEMRAVSMSPDEAPSMVAMKRVGELFDEGSSDSQVMIV
MLBr_02378|M.leprae_Br4923 TVSVFIPSLEDVGQERSVSLSPKDAPSYIAMQKMGQVFNEGNSDSVIMIV
Rv0402c|M.tuberculosis_H37Rv VVNVVAPQLQSVARTHSVALGPHDAPSLIAMKRIGKDFQQFDSDTTAMVL
MSMEG_3584|M.smegmatis_MC2_155 GTNIFVPQAEKVADELAGPMIPTYAPSQVALLQMGEKFGESDSTNLTMLV
MMAR_4975|M.marinum_M VGNLLIPQAESTARSHGRGFLPADAPVSVAGARMGEQFRDGNAGNINYLV
MAB_1520c|M.abscessus_ATCC_199 AGNLLVPQVESTAHNHARGFLPQDAPVNAAGAVMGRQFQDGAGNNLNYLV
Mb1787|M.bovis_AF2122/97 IGNNFAPPLEQVITAEDQPFSPAGTATSRAVERSAAAFSQAPGDNIGYLV
MAV_5284|M.avium_104 VANVAVPQLERVVDSHARSFMPPSAPSAVAAARAAQLFDQTPSNNFVYVV
. * : . : * :. : . * : . . ::
Mflv_3435|M.gilvum_PYR-GCK FEGDQPLGDEAHAWYDELVDRLEADTAHVQSVQDFWSDPLTASGSQSNDG
Mvan_3189|M.vanbaalenii_PYR-1 FEGDQPLGDEAHAWYDELVERLRADTKHVQSVQDFWSDPLTASGSQSNDG
MUL_0757|M.ulcerans_Agy99 LEGQEPLGAAAHKFYDKMITKLRADTKHVQSVQDFWGDPLTATGAQSGDG
TH_3260|M.thermoresistible__bu LEGEEPLGADARAFYDELVKRLEADDAHVENVQDLWSDPLTATGVQSPDG
MLBr_02378|M.leprae_Br4923 LEGDKPLGDDAHRFYDGLIRKLRAD-KHVQSVQDFWGDPLTAPGAQSNDG
Rv0402c|M.tuberculosis_H37Rv LEGQEKLGDEAHRFYDVLVTKLSQDTTHVQHIENFWGDPLTAAGSQSADG
MSMEG_3584|M.smegmatis_MC2_155 LEADRPLDDADHRFYDDLVRRLQSDPAHVQYVMDLWGEPITAAAVQSVDG
MMAR_4975|M.marinum_M LESDHRLGPAERAFYDKLLAKLRSDPTSLVSAMDLWSDPYTAKAAVSTDG
MAB_1520c|M.abscessus_ATCC_199 LESDHKLGPVEHQYHDRLLTTLRADTTHLDSAMDLWADPLTAEGALSPDG
Mb1787|M.bovis_AF2122/97 LERNGVLNDQDRAYYDALVVALRRDSRHVIEVVDWWGTPAIAEVARSDDH
MAV_5284|M.avium_104 LERNQRLGAGDRQFYDALAAALGSDHRHVYAVTDLWSQPATAAGAQSTDG
:* : *. : ::* : * * : : *. * * * *
Mflv_3435|M.gilvum_PYR-GCK KAAYVQVKLSGNQGEALANESVKAVQQTVSSLE---PPPGVRAFVTGPAA
Mvan_3189|M.vanbaalenii_PYR-1 KAAYVQVKLAGNQGESLANESVQAAQEIVRSLE---PPPGVRAFVTGPAA
MUL_0757|M.ulcerans_Agy99 KAAYVQVKLAGNQGESLANESVEAVKTIVDSLQ---APPGVKVYVTGSAA
TH_3260|M.thermoresistible__bu KSAYVQVKLAGNQGEALANESVETVREMIATVSEEMAPEGVQAFVTGGAA
MLBr_02378|M.leprae_Br4923 KAAYVQLSLAGNQGELLAQESIDAVRKIVVQTP---APPGITAWVTGASA
Rv0402c|M.tuberculosis_H37Rv KAAYVQLNLTGDQGGSQANESVAAVQRIVDSVP---PPPGIKAYVTGPGP
MSMEG_3584|M.smegmatis_MC2_155 KAAFVMLRLAGNTGKLEANESVDAVRDIVAADA---PPPGLKVYVSGPAP
MMAR_4975|M.marinum_M EAEYTMLRLAGDLGAAQANAALDAVRRTVADQP---TPPGLRAYVTGPGA
MAB_1520c|M.abscessus_ATCC_199 KAVYTMLRVNGELGAAKANDALAAVRKIVADQP---APPGTQAWVTGPGA
Mb1787|M.bovis_AF2122/97 HAVTAALRFGGMVGTSQAGESITAARSIVTQLH---PPDGLHVFVTGPGA
MAV_5284|M.avium_104 QAVSVMVRLAGMLGTAQARDSVNAVRATAQKLG---PPAGLQVHVTGPGA
.: . : . * * * :: :.: .* * . *:* ..
Mflv_3435|M.gilvum_PYR-GCK LAADQHIAGDRSMRLIEAATFTVIIVMLLLVYRSIVTVLITLVMVVMSLA
Mvan_3189|M.vanbaalenii_PYR-1 LAADQHIASDRSVRVIELVTFAVIIVMLLLVYRSIVTVLLTLVMVVLSLA
MUL_0757|M.ulcerans_Agy99 LVADQQLAGDRSLQLIEMVTFTVIIVMLLLVYRSIITAAIMLTMVVLGLL
TH_3260|M.thermoresistible__bu MSADQQEAGDSSLRVIEALTFLVITTMLLFVYRSVITVLIALFMVLIGLL
MLBr_02378|M.leprae_Br4923 LIADMHHSGDKSMIRITATSVIVILVTLLLVYRSFITVILLLFTVGIESA
Rv0402c|M.tuberculosis_H37Rv LGADRVVYGDRSLHTITGISIAVIAIMLFIAYRSLSAALIMLLTVGLELL
MSMEG_3584|M.smegmatis_MC2_155 LASDTLTIATASLKNITILTIILIVAMLLLVYRSVPSLLVPLPAVLIELL
MMAR_4975|M.marinum_M TVADEFGEIDRQMLLLTGVTVVLIALLLLAVYRSVITAAIPLVAVGLGLA
MAB_1520c|M.abscessus_ATCC_199 TIADELTAIDTQMLMITGVTVVLIAVLLFVVYRSVITAAIPLMTVGLGLA
Mb1787|M.bovis_AF2122/97 TIVDEFAAIDRQTQLITATTIVVLLILLLIVYRSAITATVPLLSVVVSLA
MAV_5284|M.avium_104 TIVDEFSAIDRQMLGITAATIGLILLLLLVVYRSPVAAAIPLISVGLALA
* . : :. :: *: .*** : : * * :
Mflv_3435|M.gilvum_PYR-GCK TARGVVAFLGHHEIIGLSTFATNLLVTLAIAAATDYAIFLIGRYQEARTA
Mvan_3189|M.vanbaalenii_PYR-1 TARGVVAFLGWHEIIGLSLFATNLLVTLAIAAATDYAIFLIGRYQEARTN
MUL_0757|M.ulcerans_Agy99 ATRGGVAFLGYHRIIGLSTFATNLLVVLAIAAATDYAIFLIGRYQEARGL
TH_3260|M.thermoresistible__bu TTRGVVAFLGYHNIIGLSTFATSLLVTLAIAIAVDYAIFLIGRYQEARSV
MLBr_02378|M.leprae_Br4923 VARGVVALLGHTGLIGLSTFAVNLLTSLAIAAGTDYGIFITGRYQEARQA
Rv0402c|M.tuberculosis_H37Rv AVRGIISTFAVNDLMGLSTFTVNVLVALTIAASTDYIIFLVGRYQEARAT
MSMEG_3584|M.smegmatis_MC2_155 AAKGVVAVLGHLGVIPLSSFAVNLLVALTLGAGTDYGIFMLGRYQEARRA
MMAR_4975|M.marinum_M VGRSIVSLLGQHNLLEVSVFSVALLGAMVLGGATDYAIFLLGRYHEARRD
MAB_1520c|M.abscessus_ATCC_199 VARSIVAFLGERDLIEVSIFSVSLLAALVLGAATDYGIFLLGRYHEQRRS
Mb1787|M.bovis_AF2122/97 VAKPIVSVLVDRDFIGISLFSLGLSVAVVVGAGTGFAMFLIGRYHERRRQ
MAV_5284|M.avium_104 LARAVVAALGQANVVEVSLFSVALMAAMTLGAGTDYAIFLVGRYHEARRG
: :: : .: :* *: : :.:. ...: :*: ***:* *
Mflv_3435|M.gilvum_PYR-GCK GEDKETAYYTMFHGTAHVVLGSGLTIAGATF---CLSFTRLPYFQTMGVP
Mvan_3189|M.vanbaalenii_PYR-1 GEDKESAYYTMFHGTAHVVLGSGLTIAGATY---CLSFTRLPYFQTLGVP
MUL_0757|M.ulcerans_Agy99 GQDRESAYYTMFGGTAHVVLGSGLTIAGATF---CLSFTRLPYFQTLGVP
TH_3260|M.thermoresistible__bu GADRATAYHTMFGGTAHVILASGLTIAGATF---CLSFTRLPYFQSLGPP
MLBr_02378|M.leprae_Br4923 NENKEAAFYTMYRGTFHVILGSGLTISGATF---CLSFARMPYFQTLGVP
Rv0402c|M.tuberculosis_H37Rv GQNREAAYYTMFGGTAHVVLASGLTVAGAMY---CLGFTRLPYFNTLASP
MSMEG_3584|M.smegmatis_MC2_155 GESREEAYFTAYRSVAPIIIGSGLTIAGACF---CLSLARLDYFHTMGPA
MMAR_4975|M.marinum_M GVEHEQALLAANRNVMPVVLASALTLAAALS---CLTFADVGLLRSAGLP
MAB_1520c|M.abscessus_ATCC_199 GVDHEQALVIANRSVAPVIAASGLTIAAALS---CLLFAQVGMLRSAGLP
Mb1787|M.bovis_AF2122/97 HIAPAAALADAYRGVAPAIAGATFIVVTSLGAVGWLSLARIGMFATTGIL
MAV_5284|M.avium_104 GVAPAQALTVAYRSIAPVVIGSALTVSVAL---ACLVFAHVGSFRSAGLP
* . : .: : : : * :: : : : .
Mflv_3435|M.gilvum_PYR-GCK LAIGMFVVVMAGVVLMVACISVATRFGKLLEPKRAMRI-RGWRKIGAAIV
Mvan_3189|M.vanbaalenii_PYR-1 LAIGMFVVVMAGVILMVAMISVATRFGKLLEPKRAMRI-RGWRKIGAAVV
MUL_0757|M.ulcerans_Agy99 LAIGMVIVVATALTLGPALIAVMSRFGKLLEPKRMARV-RGWRKIGAAIV
TH_3260|M.thermoresistible__bu LAIGMIVLIVTSLTMGPAIITVATRFG-LLEPKRAARV-RFWRKVGASVV
MLBr_02378|M.leprae_Br4923 CAVGMLIAVAVALTLGPAVLTVGSRFG-LFEPKRLIKV-RGWRRIGTVVV
Rv0402c|M.tuberculosis_H37Rv CAIGLVTVMLASLTLAPAIIAVASRFG-LFDPKRATTK-RRWRRIGTVVV
MSMEG_3584|M.smegmatis_MC2_155 VAVSMLCTIAAALTLAPALLTLGSRRG-LFDPRRLNSG-RLYRHIATSVV
MMAR_4975|M.marinum_M CAVGVLIGMLASLTLLPALLDLAGRRGLAQPRTVNRPIHRRWRRIGTMVA
MAB_1520c|M.abscessus_ATCC_199 CAIGILTGMVASLTLLPALIGLAGRRGLAQPRPLRGQPGRRWRRVGAMVS
Mb1787|M.bovis_AF2122/97 CSIGVLAVGLAALTLTPALVALASRANLLKPP-QHKRIQRQFRRLGTHVA
MAV_5284|M.avium_104 CAIGILATMVAALTLTPALMSLAVRRRYLEP--RPSRTARRWRRVGTTVA
::.:. ..: : * : : * * :*::.: :
Mflv_3435|M.gilvum_PYR-GCK RWPGPILVATMAITLVGLLALPGYKTNYNDRDYLPADLPANQGYAVADEH
Mvan_3189|M.vanbaalenii_PYR-1 RWPGPILVATLAITLVGLLALPGYKTNYNDRTYLPADLPANEGYAVADRH
MUL_0757|M.ulcerans_Agy99 RWPGPILIGAVALALVGLLTLPGYKTNYNDRNYLPADLPANEGYSAAERH
TH_3260|M.thermoresistible__bu RWPGPIMVTTVAVTLVGLLALPGYRTNYNDRNYLPASFPSNAGYEAAERH
MLBr_02378|M.leprae_Br4923 RWPLPILITTCAIAMVGLLALPGYRTNYKDRAYLPASIPANQGFAAADRH
Rv0402c|M.tuberculosis_H37Rv RWPGPVLAATLLIALIGLLALPKYQTNYNERYYIPSAAPSNIGYLASDRH
MSMEG_3584|M.smegmatis_MC2_155 RWPKPVFVASAVVVLVGAVFVPTYQVGYDDRAYQPADAPAKLGFEAADRH
MMAR_4975|M.marinum_M RWPGPVLVAAALVLLICTLPITGLTLGFNEPAAEPDSTLANRGYQATDRH
MAB_1520c|M.abscessus_ATCC_199 RWPGPVLAGSLLVLVVCALPVAGLRLGFDELAAQPLSTHANRGYQAMDRH
Mb1787|M.bovis_AF2122/97 RWPAPILVASGVFVLIMMIALPRVPIGWDEAAATPSAAESNRGYRAADRH
MAV_5284|M.avium_104 RWPGPILVAALGLTLLVALPLAGMRIGFNEPAATPSSTDSNRGYASAGRH
*** *:: : . :: : :. .:.: * :: *: .*
Mflv_3435|M.gilvum_PYR-GCK FDQARMNPELLMIESDHDLRNSADFLVIDKIAKALFRVEGIARVQAITRP
Mvan_3189|M.vanbaalenii_PYR-1 FDQARMNPELLMIESDHDLRNSADFLVIDKIAKAIFKVEGIARVQAITRP
MUL_0757|M.ulcerans_Agy99 FSQARMNPEVLMVESDHDMRNSSDFLVINKIAKAIFGVEGISRVQAITRP
TH_3260|M.thermoresistible__bu FDPARLNPELLLIESDHDLRNPADFLVIEKIAKAVFQVEGISRVQGITRP
MLBr_02378|M.leprae_Br4923 FPQARMKPEILMIESDHDMRNPADFLILDKLARGIFRVPGISRVQAITRP
Rv0402c|M.tuberculosis_H37Rv FPQARMEPEVLMVEADHDLRNPTDMLILDRIAKTVFHTPGIARVQSITRP
MSMEG_3584|M.smegmatis_MC2_155 FPQSKLMSELLMVESDHDMRNSADFISLDRAAKSLIRLPGVAMVQSITRP
MMAR_4975|M.marinum_M FPPNQLLPETVSIETDHDLRNPTGVIAIERVTRQLMTIPGIRMVQSASRP
MAB_1520c|M.abscessus_ATCC_199 FPPNRLLPEIVSIESDHDLRTPAGVIAVERVTKGLMEIPGIRMVQSASRP
Mb1787|M.bovis_AF2122/97 FAPNQLLPTQVMIETDHDIRNPAGLTAIERITAAIMAIGGVRMVQSASHP
MAV_5284|M.avium_104 FPENALLPDVIAIRADHDLRNPAGLIAIERITRHIMAVPGVRAVQSASRP
* : . : :.:***:*..:.. ::: : :: *: **. ::*
Mflv_3435|M.gilvum_PYR-GCK DGKPIKHTSIPFQMSMQGTTQRLNEKYMQDRMADMLVQADEMANTIKTME
Mvan_3189|M.vanbaalenii_PYR-1 DGKPIKHTSIPFQMSMQGTTQRLNEKYMQDRMADMLVQADEMANTIATME
MUL_0757|M.ulcerans_Agy99 DGKPIEHTSIPFLISMQGTSQKLTEKYNQDLTTSMLQQVNDIQTNIDQME
TH_3260|M.thermoresistible__bu EGTPIEHSSIPFMISQQGTLQILNQQYMQDRMADMLVQADEMQLMIDTMD
MLBr_02378|M.leprae_Br4923 DGTAMDHTSIPFQISMQNAGQVQTMKYQKDRMNDLLRQAENMAETIASMR
Rv0402c|M.tuberculosis_H37Rv LGAPIDHSSIPFQLGMQSTMTIENLQNLKDRVADLSTLTDQLQRMIDITQ
MSMEG_3584|M.smegmatis_MC2_155 LGRPLEHATIPYLFTMQGSTSGQQLPFDQQLNENTDRQADIQAHSLQVIQ
MMAR_4975|M.marinum_M AGSVPDEATLANQAGAIGDRLDQRIAQLDHRFSSINVIAPTLSRFSAAIS
MAB_1520c|M.abscessus_ATCC_199 AGTIPEQAALTEQAGIIADQLDDGTAQMSQRLGAVDKLSATLSQFSGAIA
Mb1787|M.bovis_AF2122/97 NGMVSKQAALTASAGNLGDQLDEFSDQLTSRQATFTNLEAAVRDVVSALD
MAV_5284|M.avium_104 DGKVPEQATLSYQAGVLGRQFGDTVDSLTQRLARVSELDGALAQTQQAVD
* ..:::.
Mflv_3435|M.gilvum_PYR-GCK KMSGLTAQMADITHSMVTKMEGMVVDIEDLRDSIANFDDFFRPIRNYFYW
Mvan_3189|M.vanbaalenii_PYR-1 KMSNLTAQMADITHSMVSKMENMLTDIEDLRDSIANFDDFFRPIRNYFYW
MUL_0757|M.ulcerans_Agy99 RMHDLTQQMADVTHQMVIQMKGMVVDVEELRNHIADFDDFFRPIRSYFYW
TH_3260|M.thermoresistible__bu KMIALMEEMVETTDNMVRDMDEMAAHVAEMRDSISEFDDFFRPIRNYFYW
MLBr_02378|M.leprae_Br4923 RMHQLMALLTENTHHILNDTVEMQKTTSKLRDEIANFDDFWRPIRSYFYW
Rv0402c|M.tuberculosis_H37Rv RTQELTRQLTDATHDMNAHTRQMRDNANELRDRIADFDDFWRPLRSFTYW
MSMEG_3584|M.smegmatis_MC2_155 QVISITTQMSDELHATTVTFENLKEVTDEVNEGISDLDDFLRPLKNYFYW
MMAR_4975|M.marinum_M RLQEQLSGSANGLGRVNSGIDAMDSGLVQLHDTAAQVSGYLNPLRDYTNS
MAB_1520c|M.abscessus_ATCC_199 QLQKGLAGGVNGLGELNGGIGDMHSGMKALQDNVSQVSGYMEPLRNFTNG
Mb1787|M.bovis_AF2122/97 LVQAGIRQDGYGLGQVSLAVRLMQQAITKLQGSAGDVFDIFDPLRRFVAA
MAV_5284|M.avium_104 GLGNGLHGGSAGLADMSGAADDMRAGMDGLQRNVTTVSGYLDPLRDLVGR
: :. . . *::
Mflv_3435|M.gilvum_PYR-GCK EPHCYNIPVCWALRSVFDTLDGINIMTDDFKAIIPDMKRLDTLMPQMVAL
Mvan_3189|M.vanbaalenii_PYR-1 EPHCYNIPVCWALRSVFDTLDGINVMTDDFREILPDMKRLDSLMPQMVAL
MUL_0757|M.ulcerans_Agy99 EKHCFDIPVCWSLRSVFDTLDGVDLMTEDINNLLPLMERLDTLMPQMTAM
TH_3260|M.thermoresistible__bu EPHCYNIPVCWAMRSVFDTLDGINTMTDDIQNMLPHMHRLNDLMPQMLTL
MLBr_02378|M.leprae_Br4923 ERHCFNIPICWSFRSIFDALDGVDQIDERLNSIVGDIKNMDLLMPQMLEQ
Rv0402c|M.tuberculosis_H37Rv ERHCFDIPICWSMRSLLNSMDNVDKLTEDLANLTDDTERMDTTQRQLLAQ
MSMEG_3584|M.smegmatis_MC2_155 EPHCFDIPVCFAIRSLFDSLDGIDRLDEQIGNAVESFEAIDRLLPQMITQ
MMAR_4975|M.marinum_M VANCPSDPVCALVLKVIDPADSIVVETNSLAKGTSQLGAGMSD---TAKS
MAB_1520c|M.abscessus_ATCC_199 NPNCANDGICSLVLKAVEPMDSVVAATASLTASTTKFGAGAQG---MQKS
Mb1787|M.bovis_AF2122/97 IPECRANPVCSVAQEVVQWANTVTESCAKLADAAGQLARGIADVASATSG
MAV_5284|M.avium_104 TPDCAANPICSMVDRVLAPVDSLVQTSAQLGSGAAKLTTGSN---TAATA
.* :* . : : :
Mflv_3435|M.gilvum_PYR-GCK MPEMIETMKTMRTMMLTMYQSQKGQQDQMAAMS--------EDADAMGEA
Mvan_3189|M.vanbaalenii_PYR-1 MPEMIETMKTMRTMMLTMYQSQKGQQDQMAAMS--------EDADAMGEA
MUL_0757|M.ulcerans_Agy99 MPEMIQTMKSMKAQMLSMHSTQQGLQDQMAAMQ--------EDSSAMGEA
TH_3260|M.thermoresistible__bu LPTTVATMKTMRSMLLTMQATNAGLQDQMAEMQ--------ENANAMGEA
MLBr_02378|M.leprae_Br4923 FPPMIESMESMRTIMLTMHSTMSGIFDQMNELS--------DNANTMGKA
Rv0402c|M.tuberculosis_H37Rv LDPTIATMQTVKDLAQTLTSAFSGLVTQMEDMT--------RNATVMGRT
MSMEG_3584|M.smegmatis_MC2_155 LEQMKIAGKATLSLLQNNYGSAHLQSTQTDQTY--------DDLINVGND
MMAR_4975|M.marinum_M LTTADQSLAIMGADMAQLSATTAQLADAVHDAH-TAISDIIDYLRGLRQG
MAB_1520c|M.abscessus_ATCC_199 FSGAVDSVKNMRATVAQLGAITDQLTHAVGETR-TMFSGLTEYLRAMRED
Mb1787|M.bovis_AF2122/97 VSGLPNALDGIGGQLAQVRESAAGVQELLNNVGAAPLRELPDYLRELAAV
MAV_5284|M.avium_104 MAGLPQNVDAMKSALVQARSATRDLLGLSDTLG-PQMRQLTDYLNEISTQ
. :
Mflv_3435|M.gilvum_PYR-GCK FDDSMNDDSFYLPPEIFENADFQRGLEQFLSPDGHAVRFIISHEGDPLSP
Mvan_3189|M.vanbaalenii_PYR-1 FDDSMNDDSFYLPPEIFENKDFQRGLEQFLSPDGHAVRFIISHEGDPLSP
MUL_0757|M.ulcerans_Agy99 FDSSRNDDSFYLPPEVFNNPDFKRGLEQFLSPDGHAVRFIISHEGDPMSQ
TH_3260|M.thermoresistible__bu FDQARNDDSFYLPPEAFDNPDFQRGLEQFLSPDGHAVRFIISHQGDPMTP
MLBr_02378|M.leprae_Br4923 FDTAKNDDSFYLPPEVFKNTDFKRAMKSFLSSDGHAARFIILHRGDPASV
Rv0402c|M.tuberculosis_H37Rv FDAANNDDSFYLPPEAFQNPDFQRGLKLFLSPDGTCARFVITHRGDPASA
MSMEG_3584|M.smegmatis_MC2_155 FDAARSDDFFYIPHEAFDNDDVKTGMKLLMSPDGKAARFIITHEGNAMAQ
MMAR_4975|M.marinum_M FQGSAEGT-FYLPQQAWNDPRFQRAANLYFSPDGHVTRLLVFGDGAVFGG
MAB_1520c|M.abscessus_ATCC_199 FRSSGEGG-YYLPQRAWQDPRFQRAAGLYFGPDGHSTRMLVFGDGKVFGA
Mb1787|M.bovis_AF2122/97 SQSAPGVD-LYAARRILTDPNMRAVLDYFVSPNGHATRLLVYGDGSEWGD
MAV_5284|M.avium_104 FQGSAAAD-FYLPQRALTDPRYTAVLNHLISQTGRAAYLLVYGDGAEWGA
: * . . : .. * . ::: *
Mflv_3435|M.gilvum_PYR-GCK EGVAKIDKIKTAAKEAVKGTPLEGSKIYLGGTAAVFKDMQDGNNYDLLIA
Mvan_3189|M.vanbaalenii_PYR-1 EGVAKIDKIKTAAKEAIKGTPLEGSKIYLGGTAATFKDMQDGNNYDLLIA
MUL_0757|M.ulcerans_Agy99 AGINHIDKIKTAAKEAIKGTPLEGSTIYLGGTVAMFKDLSDGNTFDLMIA
TH_3260|M.thermoresistible__bu EGLAKIEPIKKAAVEAIKGTPLEGSRVYLGGTAAVFKDMSDGTKYDLIIA
MLBr_02378|M.leprae_Br4923 AGIASINAIRTAAEEALKGTPLEDTKIYLAGTAAVFKDIDEGANWDLVIA
Rv0402c|M.tuberculosis_H37Rv EGISHIDPIMQAADEAVKGTPLQAASIYLAGTSSTYKDIHEGTLYDVMIA
MSMEG_3584|M.smegmatis_MC2_155 EGIEHVEQIPDAIKMALKETSLAGAKVYLGGAASSTKDIQDYAASDLLIV
MMAR_4975|M.marinum_M DGANRSPQIVAAVKAATKEGVLAGSTVNIAGFGTATAELRGYVHHDFVLL
MAB_1520c|M.abscessus_ATCC_199 DGAHRSPQIMLAVSEATKEGTLAGSSVNLTGFGTGTAELRGYVSEDFLLL
Mb1787|M.bovis_AF2122/97 DGAQRARAIVTAVAEETDEGTLRPTAVELTGVGPATRDLQDLVGSDLTLL
MAV_5284|M.avium_104 DSAERAEQVRAAIKEATKEGTLTPVEVDLAGVGPVTADLQRFVADDTRLL
. : * . * : : * . :: * :
Mflv_3435|M.gilvum_PYR-GCK GIAALGLIFIIMLILTRAVVAAAVIVGTVVLSLAASFGLSVLFWQHILGQ
Mvan_3189|M.vanbaalenii_PYR-1 GISALGLIFIIMLILTRAIVAAAVIVGTVVLSLAASFGLSVLFWQHILGT
MUL_0757|M.ulcerans_Agy99 GISALCLIFIIMLIITRSVVAAAVIVGTVVLSLGASFGLSVLIWQHVLGI
TH_3260|M.thermoresistible__bu AIAAVCLIFIIMLILTRAVVAAAVIVGTVTLSLAASFGVSVLIWQYIVGL
MLBr_02378|M.leprae_Br4923 GISSLCLIFIIMLIITRAFVAAAVIVGTVALSLGASFGLSVLLWQHILGI
Rv0402c|M.tuberculosis_H37Rv VVASLCLIFIIMLGITRSVVASAVIVGTVALSLGSAFGLSVLIWQHILHM
MSMEG_3584|M.smegmatis_MC2_155 AIAAFVLIFLIMLYLTRSLVAAMVIPGTVAFSFAGAFGLSVLVWQHLIGL
MMAR_4975|M.marinum_M AAAALALVFLIVLLMLRSPVAAAVVIGAVIVSYLSALGISTFIWHDLLGK
MAB_1520c|M.abscessus_ATCC_199 AAVALALVFLIVLVMLRSPVAAAVVIGTVIISYASALGVTTLIWQDLLGR
Mb1787|M.bovis_AF2122/97 AVITLAVIFAIAALLLRSPLAGLVVVGTIATSYICALGASVVIWKHILGD
MAV_5284|M.avium_104 VGAALVLIFLIVTAMLRSPVAGLVVVGTVVTSYASAIGASVLIWQHLLHQ
:. ::* * : *: :*. *: *:: * ::* :...*: ::
Mflv_3435|M.gilvum_PYR-GCK PLHWMVLAMAVIILLAVGADYNLLLVSRLKEEI------HAGIGTGIIRA
Mvan_3189|M.vanbaalenii_PYR-1 ELHWMVLAMAVIVLLAVGADYNLLLVSRLKEEI------HAGIGTGIIRA
MUL_0757|M.ulcerans_Agy99 ELHWLVLAMAVIILLAVGADYNLLLVARLKEEI------HAGINTGIIRA
TH_3260|M.thermoresistible__bu EMHWMVFPMALIILLAVGADYNLLVVARLREEI------PAGLNTGMIRA
MLBr_02378|M.leprae_Br4923 ELHYLVLAMSVIVLLAVGSDYNLLLVSRFKQEI------QAGLKTGIIRS
Rv0402c|M.tuberculosis_H37Rv PLHWLVLPMAIIVMLAVGSDYNLLLIARFQEEI------GAGLKTGMIRA
MSMEG_3584|M.smegmatis_MC2_155 PLHWLVLPLAFIILVAVGSDYNLLLISRVKEES------GAGLNTALIRA
MMAR_4975|M.marinum_M DLHWAVQSMAFISLVAVGADYNLLLTVRVREEVLAHPDRGVGLRTATIRA
MAB_1520c|M.abscessus_ATCC_199 DLHWAVPSIALIALVAVGADYNLLLTMRMREEVFLH---GAGLRTGMIRT
Mb1787|M.bovis_AF2122/97 NLHWSVLPIAFVLLISVGSAYNLLFALRIREE------SPAGPRTSVIRA
MAV_5284|M.avium_104 ELHWAVAPIAFIALIAVGADYNLLLALRIKQE------AAAGLRTGIIRA
:*: * .::.: :::**: ****. *.::* .* *. **:
Mflv_3435|M.gilvum_PYR-GCK MGGSGSVVTAAGLVFALTMMSMSVSELTVIGQVGTTIGLGLLFDTLVIRA
Mvan_3189|M.vanbaalenii_PYR-1 MGGSGSVVTAAGLVFALTMMSMAVSELTVIGQVGTTIGLGLLFDTLVIRA
MUL_0757|M.ulcerans_Agy99 MGGSGSVVTAAGLVFAFTMMSFAVSELTVMAQVGTTIGMGLLFDTLIVRS
TH_3260|M.thermoresistible__bu MGGSGSVVTAAGLVFGLTMMVMVVSDLTVMGQVGTTIGLGLLFDTFVVRS
MLBr_02378|M.leprae_Br4923 MGGTGKVVTNAGLVFAFTMASMVVSDLRVIGQVGTTIGLGLLFDTLIVRS
Rv0402c|M.tuberculosis_H37Rv MAGTGRVVTIAGLVFAFTMGSMVASDLRVVGQIGTTIMIGLLFDTLVVRS
MSMEG_3584|M.smegmatis_MC2_155 LGSTGAVVTSAGLVFAFTMLSMLASNLAAVGQLGSTVCIGLLLDTMIVRS
MMAR_4975|M.marinum_M FGGAGGVVTTAGIVFAITMFAMASSDVLSIEQVGTTIGAGLIVDTLVVRI
MAB_1520c|M.abscessus_ATCC_199 FGGTGGVVTTAGIVFGITMFAMLSSDVLSIEQTGTTIGVGLMIDTLIVRT
Mb1787|M.bovis_AF2122/97 FAATGMVVTAAGIVFGTTMFALAASTSLSVAQIGVTVGMGLLLDALVIRG
MAV_5284|M.avium_104 FGGTGGVVTVAGIIFGLTMLALLTSSVLSIAQIGTTIAVGLLLDTLVVRA
:..:* *** **::*. ** : * : * * *: **:.*::::*
Mflv_3435|M.gilvum_PYR-GCK FMTPSIAALLGPWFWWPQRVRTRPVPAPWPRSGGLQSDPSEGVRA-----
Mvan_3189|M.vanbaalenii_PYR-1 FMTPSIAALLGPWFWWPQRVRTRPVPAPWPRPGGLQSDPSEGVKV-----
MUL_0757|M.ulcerans_Agy99 FMTPSIAALLGKWFWWPQVVRQRPAPQPWPTPAPTPPPATTSV-------
TH_3260|M.thermoresistible__bu FMMPSIATLLGRWFWWPQFVRKRPVPQPWPSVPPRGPATTDRVSV-----
MLBr_02378|M.leprae_Br4923 FMMPSIAALLGRWFWWPQQGRTRPLLTVAAPVG-LPPDRSLVYSD-----
Rv0402c|M.tuberculosis_H37Rv YMTPALATLLGRWFWWPRRVDRLARQPQVLGPRRTTALSAERAALLQ---
MSMEG_3584|M.smegmatis_MC2_155 LVVPCLLRLLGPWFWWPTFIRQRPLRTPDRFARPGPSRRIMTDR------
MMAR_4975|M.marinum_M FAVPAIMGLLGRWFWWSPPPFLRASLAGPRRWGPWLRKRIASARRWLSTS
MAB_1520c|M.abscessus_ATCC_199 FVVPAIAGALGKWFWWSPVPLLRGLLF---RWSKARSPRTAGVLSYLLT-
Mb1787|M.bovis_AF2122/97 FVLPALMVLLGRWLWWP----RRSVS-----NRQVPEPSPA---------
MAV_5284|M.avium_104 FIVPSIVALLGRWFWWPSPLPRRGVAR----VVKTVEPQPVSVATAV---
*.: ** *:**.
Mflv_3435|M.gilvum_PYR-GCK ---------------
Mvan_3189|M.vanbaalenii_PYR-1 ---------------
MUL_0757|M.ulcerans_Agy99 ---------------
TH_3260|M.thermoresistible__bu ---------------
MLBr_02378|M.leprae_Br4923 ---------------
Rv0402c|M.tuberculosis_H37Rv ---------------
MSMEG_3584|M.smegmatis_MC2_155 ---------------
MMAR_4975|M.marinum_M VLAASVRYLRRTASG
MAB_1520c|M.abscessus_ATCC_199 ----RPSRLERTGA-
Mb1787|M.bovis_AF2122/97 ---------------
MAV_5284|M.avium_104 ---------------