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MQPARGNGAGTVLICGAGIAGTVVAYRLARAGLRPTVVERSADLRQAGNAVDLRGPALQVMADMGVLAEL ETRATQLSEFFRIDSSGKRVFTMAPHVIGGEIELLRTELNAVLFNAAQTGVEYRFGDSIRSLHERGDDVA VTFDSGRHGHFDVVIGADGLHSRTRTLAFGPESDFVRHLGCYQAHFTTGNVLGLRNAGLLLNRPGRTLGC YTVHQSRELVIGLFFESAQRAYDRADPAAQRHWIHRVFEGMGWRTAELLEAMWTCDDFYFDSIAQVSLAN PCRGRVALIGDAAYGPSLFSGMGATLAVVGAAILADEISCHPGDHRQAFTRYQRRIREMARLSRELAQAS RGWFMPPADAHDIPPESQLAADRESDVLRDRTLAAMQAAFGNPSSPARN
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_1431 | - | - | 100% (399) | hypothetical protein MAB_1431 |
| M. abscessus ATCC 19977 | MAB_0649c | - | 5e-58 | 36.96% (349) | putative monooxygenase |
| M. abscessus ATCC 19977 | MAB_2678 | - | 1e-56 | 36.93% (352) | hypothetical protein MAB_2678 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0590c | - | 1e-45 | 34.09% (352) | hypothetical protein Mb0590c |
| M. gilvum PYR-GCK | Mflv_2621 | - | 1e-06 | 23.85% (327) | monooxygenase, FAD-binding |
| M. tuberculosis H37Rv | Rv1260 | - | 2e-58 | 40.24% (328) | hypothetical protein Rv1260 |
| M. leprae Br4923 | - | - | - | - | - |
| M. marinum M | MMAR_2185 | - | 1e-55 | 38.23% (361) | oxidoreductase |
| M. avium 104 | MAV_1408 | - | 3e-59 | 39.53% (344) | hypothetical protein MAV_1408 |
| M. smegmatis MC2 155 | MSMEG_3039 | - | 1e-55 | 37.53% (373) | monooxygenase |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | MUL_1770 | - | 5e-56 | 38.23% (361) | oxidoreductase |
| M. vanbaalenii PYR-1 | Mvan_5278 | - | 2e-10 | 23.39% (342) | monooxygenase, FAD-binding |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_2185|M.marinum_M ------MAKPIVLISGAGIAGPALAFWLTHSGYQVVVTELADDIRPGGQT
MUL_1770|M.ulcerans_Agy99 ------MAKPIVLISGAGIAGPALAFWLTHSGYQVVVTELADDIRPGGQT
MSMEG_3039|M.smegmatis_MC2_155 ------MGQPTVLISGAGVAGTSLAHWLTEYGYRAVVVETAPTLRLGGQT
Rv1260|M.tuberculosis_H37Rv --------MKTVVVSGASVAGTAAAYWLGRHGYSVTMVERHPGLRPGGQA
MAV_1408|M.avium_104 --------MSDVLVSGASVAGTAAAFWLGRHGHSVTVVERHRGPRPGGQA
MAB_1431|M.abscessus_ATCC_1997 MQPARGNGAGTVLICGAGIAGTVVAYRLARAGLRPTVVERSADLRQAGNA
Mb0590c|M.bovis_AF2122/97 ---------MKVAISGAGVAGAALAHWLQRTGHTPTVIERAPKFRTGGYM
Mflv_2621|M.gilvum_PYR-GCK -------MSARISVIGAGISGLAAAVALERAGHHVSVIEQRTDTG-AGSG
Mvan_5278|M.vanbaalenii_PYR-1 ---------MKVVIVGAGMGGMSAAIALRQIGIDTVVYERVTENKPVGAA
: : **.:.* * * . * : * *
MMAR_2185|M.marinum_M VDLRGAGRLVIERMGLLEQMRQRSLRQRGIAWIR-ADGR---RRAEMPVE
MUL_1770|M.ulcerans_Agy99 VDLRGAGRLVIERMGLLEQMRQRSLRQRGIAWIR-ADGR---RRAEMPVE
MSMEG_3039|M.smegmatis_MC2_155 VDLRGAGRDVVTRMGLLDEMRARSLDQRGIAWVR-GNGR---RRAEMPVD
Rv1260|M.tuberculosis_H37Rv IDVRGPALDVLERMGLLAAAQEHKTRIRGASFVD-RDGNELFRDTES---
MAV_1408|M.avium_104 IDVRGPALGVLERMGLLAAAAKRRTQIRGSSVVD-RDGNELSRDTEAAIS
MAB_1431|M.abscessus_ATCC_1997 VDLRGPALQVMADMGVLAELETRATQLSEFFRID-SSGK---RVFTMAPH
Mb0590c|M.bovis_AF2122/97 IDFWGVGYQVAKRMGITDQIAAAGYHMEHVRSVG-PTGKVKADLGVDVFR
Mflv_2621|M.gilvum_PYR-GCK ISLWPNALAALDQIGLGDSVRDAGGRVTAGAIRW-RDGTWVRRPSVRRIV
Mvan_5278|M.vanbaalenii_PYR-1 ISVWSNGVKCLNYLGLQEETAELGGKVETMSYVDGHTGDTMCRFSMHPLI
:.. . :*: *
MMAR_2185|M.marinum_M AFHGNGPVS-ELEILRGDLAAVLYRAT-AAGTDYRFGTRITDLAPSGDAV
MUL_1770|M.ulcerans_Agy99 AFHGNGPVS-ELEILRGDLAAVLYRAT-AAGTDYRFGTRITDLAPSGDAV
MSMEG_3039|M.smegmatis_MC2_155 AFDGNGMVS-ALEILRGDLVEVLYNAT-SARAEYRFGTRITEIDSSG---
Rv1260|M.tuberculosis_H37Rv TPTGGPVNSPDIELLRDDLVELLYGAT-QPSVEYLFDDSISTLQDDGDSV
MAV_1408|M.avium_104 GPTGGPIEGPDIELLRDDLVELLYGAS-QWTAEYLFDDTITALDDRGAAV
MAB_1431|M.abscessus_ATCC_1997 VIGG------EIELLRTELNAVLFNAA-QTGVEYRFGDSIRSLHERGDDV
Mb0590c|M.bovis_AF2122/97 RMVGDDFTS----LPRGDLAAAIYTTI-EDQVETIFDDSIATIDEHRDGV
Mflv_2621|M.gilvum_PYR-GCK DALGEP-----LVVVRRSRLTDILREA-LPAGTVRTGLAATRVSVGASSV
Mvan_5278|M.vanbaalenii_PYR-1 EQVGQRPYP----IARAELQLMLMKAYGIDDINFGMKMVGVENDTAGSAA
* : * . :
MMAR_2185|M.marinum_M QARLSDGTTVRADLVVGADGPHSGVRRLAFG-PEEQFARPLGGYNAWFSA
MUL_1770|M.ulcerans_Agy99 QARLSDGTTVRADLVVGADGPHSGVRRLAFG-PEEQFARPLGGYNAWFSA
MSMEG_3039|M.smegmatis_MC2_155 -ATLSDGTRVDADLIVGADGPHSSVRRMVFG-PEEQYVTLLGGYNAWFTA
Rv1260|M.tuberculosis_H37Rv RVTFERAAAREFDLVIGADGLHSNVRRLVFG-PEEQFVKRLGTHAAIFTV
MAV_1408|M.avium_104 RVSFERAAPRDFDLVIGADGLHSNVRRLVFG-PEDEFIERLGTHAAIFTV
MAB_1431|M.abscessus_ATCC_1997 AVTFDSGRHGHFDVVIGADGLHSRTRTLAFG-PESDFVRHLGCYQAHFTT
Mb0590c|M.bovis_AF2122/97 RLTFERTAPRDFDLVIGADGLHSNVRRLVFG-PERDFEHYLGCKVAACVV
Mflv_2621|M.gilvum_PYR-GCK RITLSDGEVRESDAVVGADGVNSVLARTLNG-PLRTRYVGYTAWRGIAAH
Mvan_5278|M.vanbaalenii_PYR-1 KATFADGTTVSADVIIGADGAGSITREYVLGGPVSRRYAGYVNYNGLVST
: * ::**** * * * .
MMAR_2185|M.marinum_M PDTVGLNGWYLMYQAPGGLNASMRPSHDPATAKAGLAFRSAPIRYDRGDL
MUL_1770|M.ulcerans_Agy99 PDTVGLNGWYLMYQAPGGLNASMRPSHDPATAKAGLAFRSAPIRYDRGDL
MSMEG_3039|M.smegmatis_MC2_155 PDTAGLDGWYLMYQVPG-LNASMRPSHDPALCKAGLAFRSGPVDYDRRDP
Rv1260|M.tuberculosis_H37Rv PNFLELD-YWQTWHYGDSTMAGVYSARNNTEARAALAFMDTELRIDYRDT
MAV_1408|M.avium_104 PNFLGLD-YWQMWHYGDSTMAGVYSARDNAEARAMLGFMDAELRLDYRDT
MAB_1431|M.abscessus_ATCC_1997 GNVLGLRNAGLLLNRPG-RTLGCYTVHQSRELVIGLFFESAQRAYDRADP
Mb0590c|M.bovis_AF2122/97 DGYRPRDERSYVLYNTVDRQLARFALRGDR-----TMFLFVFRAEHDNPG
Mflv_2621|M.gilvum_PYR-GCK PLDPELG--------GETLGPGTQVGHVPLGPDHTYWFATERTAEGGSAP
Mvan_5278|M.vanbaalenii_PYR-1 DDAIGPATEWTTYVGDGKRVSVMPVS----DDRFYFFFDVVEPQGSPYEE
*
MMAR_2185|M.marinum_M DAQRDLLAARFAGAGWQSDALIAAAREADDFYLDAIVQIHLDAWSRGRVT
MUL_1770|M.ulcerans_Agy99 DAQRDLLAACFAGAGWQSDALIAAAREADDFYLDAIVQIHLDAWSRGRVT
MSMEG_3039|M.smegmatis_MC2_155 ATQLALLNTHFAGAGWHCADLLAAAAVADDFYFDAFLQVHMPTLSRGPVT
Rv1260|M.tuberculosis_H37Rv EAQFAELQRRMAEDGWVRAQLLHYMRSAPDFYFDEMSQILMDRWSRGRVA
MAV_1408|M.avium_104 EAQFAELERRMAGEGWVRPQLLEYMRTAPDFYFDEMSQIKMDRWSRGRVA
MAB_1431|M.abscessus_ATCC_1997 AAQRHWIHRVFEGMGWRTAELLEAMWTCDDFYFDSIAQVSLANPCRGRVA
Mb0590c|M.bovis_AF2122/97 VAPKDELRDQFGDVGWESRDILAALDDVEDLYFDVVSQIRMDRWSRGRVL
Mflv_2621|M.gilvum_PYR-GCK GGEHAYLTAKVADWADPIPRLVATTDPGDLLRNDLYDRARAARWSDGRAV
Mvan_5278|M.vanbaalenii_PYR-1 GRVREVLRAHFAGWTPGVQTLIDTLDPLATNRVEILDLDPFHTWVKGRVA
: . :: : * .
MMAR_2185|M.marinum_M LVGDAGYCASPLSGMGTSLALVGAYVLAGELGPAHGDGIDEAALAAALAR
MUL_1770|M.ulcerans_Agy99 LVGDAGYCASPLSGMGTSLALVGAYVLAGELGPAHGDGIDEAALAAALAR
MSMEG_3039|M.smegmatis_MC2_155 LVGDAGYCASPLSGMGTSLALVGAYVLAGELGPA--DMFAHAKLGLALSR
Rv1260|M.tuberculosis_H37Rv LVGDAGYCCSPLSGQGTSVALLGAYILAGELKAAG------DDYQLGFAN
MAV_1408|M.avium_104 LVGDAGYCCSPLSGQGTSVALLGAYILAGELKAAG------EDHEAGFAN
MAB_1431|M.abscessus_ATCC_1997 LIGDAAYGPSLFSGMGATLAVVGAAILADEISCHP------GDHRQAFTR
Mb0590c|M.bovis_AF2122/97 LIGDAAGCISLLGGEGTGLAITEAYVLAGELARAG------GDHRRAFDA
Mflv_2621|M.gilvum_PYR-GCK LIGDAAHPMRPHLGQGGCQGIEDAAILARFLELAD-------DVPTAFER
Mvan_5278|M.vanbaalenii_PYR-1 VLGDAAHNTTPDIGQGGCSAMEDAIALQWAFKDHP------DDVHAALAA
::***. * * .: * * : .:
MMAR_2185|M.marinum_M YETVLRPYVANCQDLPNS-IDRFLPMSESEIRSNAAAMKYMQRWPFRFFA
MUL_1770|M.ulcerans_Agy99 YETVLRPYVANCQDLPNS-IDRFLPMSESEIRSNAAAMKYMQRWPFRFFA
MSMEG_3039|M.smegmatis_MC2_155 YESTMRPYIERCQDLPTG-IDGYLPKSALDITIYTQVMKWMQRWPIRSYA
Rv1260|M.tuberculosis_H37Rv YHAEFHGFVERNQWLVSDNIPGGAPIPQ----------EEFER-------
MAV_1408|M.avium_104 YHREFADYVQRNQWLVVDNIPGGAPIPQ----------EVFER-------
MAB_1431|M.abscessus_ATCC_1997 YQRRIREMARLSRELAQASRGWFMPPADAHDIPPES--QLAADRESDVLR
Mb0590c|M.bovis_AF2122/97 YEKRLRPFIEGKQASAAKFIWFFRHPNPIRPVVSQRCDAHDELRP-----
Mflv_2621|M.gilvum_PYR-GCK FEAFRKPRVGMLVREAQTLGRIVNVRPAVLSGLAGRATALIPERMVT--A
Mvan_5278|M.vanbaalenii_PYR-1 YQSARTERAADLVLRARKRCDVTHAKDP--QVTSRWYDELRNEDGTNIIR
:.
MMAR_2185|M.marinum_M ERKWFTIAESIELPRYPRLP---
MUL_1770|M.ulcerans_Agy99 ERKWFTIAESIELPRYPRLP---
MSMEG_3039|M.smegmatis_MC2_155 ARKWFTTADAIQLPSYPAAQNKR
Rv1260|M.tuberculosis_H37Rv ------IVHSITIKDY-------
MAV_1408|M.avium_104 ------IVASITLKDY-------
MAB_1431|M.abscessus_ATCC_1997 DRTLAAMQAAFGNPSSPARN---
Mb0590c|M.bovis_AF2122/97 ------AGDAVRRQRA-------
Mflv_2621|M.gilvum_PYR-GCK HLAWIAAGSAFVLPTAADLAR--
Mvan_5278|M.vanbaalenii_PYR-1 GIVGNIVGGPLTPVTAATEG---
..