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MSRVDMASAPAATIGSVVELDSLLRQLATGTLSETNVATSRLLDAAREEFVAHGIARTAVGDIARRAGVS RPTLYRKCGDKEDIVAAVLVRETTEFFVRAQAVLAPLSNAEDRMVEAFVMGMREARHHPLVAALKEFDSE SFSRNVFDVNTAGYQGLLAVIAELLSDDSYPVPAVKRALDLALRLTSTFLVNPSDLLPTDTDTNTREFAI RYLLPLMRAAR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_2152 | - | - | 100% (221) | TetR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_3273c | - | 7e-49 | 48.06% (206) | TetR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_1024 | - | 2e-20 | 32.80% (186) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2274c | - | 3e-07 | 48.98% (49) | transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_0059 | - | 7e-16 | 30.10% (196) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv1255c | - | 2e-09 | 27.60% (192) | transcriptional regulatory protein |
| M. leprae Br4923 | MLBr_02568 | - | 2e-07 | 32.18% (87) | putative TetR-family transcriptional regulator |
| M. marinum M | MMAR_0287 | - | 1e-17 | 30.56% (180) | transcriptional regulatory protein |
| M. avium 104 | MAV_5227 | - | 2e-16 | 28.89% (180) | TetR-family protein transcriptional regulator, putative |
| M. smegmatis MC2 155 | MSMEG_0962 | - | 1e-16 | 30.60% (183) | TetR-family protein transcriptional regulator |
| M. thermoresistible (build 8) | TH_2255 | - | 1e-16 | 32.09% (187) | TetR-family protein transcriptional regulator |
| M. ulcerans Agy99 | MUL_4837 | - | 1e-17 | 30.56% (180) | transcriptional regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_0855 | - | 3e-17 | 31.18% (186) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_0287|M.marinum_M ------------------MQSRMGTETSTDGVESITDLDRTILDTARAVF
MUL_4837|M.ulcerans_Agy99 ----------------------MGTETSTDGVESITDLDRTILDTAHAVF
MAV_5227|M.avium_104 ----------------------MQSHRADAAAGERTDLDRLILDTARGVF
Mflv_0059|M.gilvum_PYR-GCK ------------------------------MS-GPDPASEQILDAAVVEF
Mvan_0855|M.vanbaalenii_PYR-1 ------------------------------MR-GTD-ATEHILDAAVVEF
MSMEG_0962|M.smegmatis_MC2_155 ------------------------------MP-GPDAASRAILDAALVEF
TH_2255|M.thermoresistible__bu ------------------------------MPERPDPARQAILDAAVVEF
MAB_2152|M.abscessus_ATCC_1997 MSRVDMASAPAATIGSVVELDSLLRQLATGTLSETNVATSRLLDAAREEF
Rv1255c|M.tuberculosis_H37Rv -----------------------MAGTDWLSARRTELAADRILDAAERLF
Mb2274c|M.bovis_AF2122/97 ---------------------------MLSMSNDRADTGGRILRAAASCV
MLBr_02568|M.leprae_Br4923 -------------------------MAGGAKRIPRAVREQQMLDAAVQMF
:* :* .
MMAR_0287|M.marinum_M ETYGVRRANIEDVATRAGVSRSTIYRRFPTKDELFERVVRREAELFFAAL
MUL_4837|M.ulcerans_Agy99 ETYGVRRANIEDVATRAGVSRSTIYRRFPTKDELFERVVRREAELFFAAL
MAV_5227|M.avium_104 ETYGVRRANIDDVAARAGVSRSTIYRRFPTKKNLFGQVVRREAELFFSTL
Mflv_0059|M.gilvum_PYR-GCK ERHGFRRVALEDVARRAGVSRTTIYRRFANKDQLVGAVIERENVALFSDI
Mvan_0855|M.vanbaalenii_PYR-1 ERHGFRRVALDDVARRAGVSRTTIYRRFANKDELVGAVIERENIQLFADI
MSMEG_0962|M.smegmatis_MC2_155 ERYGFRRVALDDVARRAGVSRTTIYRRFANRDDLVGAVIERENVSLFADI
TH_2255|M.thermoresistible__bu EQHGFRKVALEDVARRAGVSRTTIYRRFTNRDELVAAVVDRENAALFADI
MAB_2152|M.abscessus_ATCC_1997 VAHGIARTAVGDIARRAGVSRPTLYRKCGDKEDIVAAVLVRETTEFFVRA
Rv1255c|M.tuberculosis_H37Rv TQRDPASIGMNEIAKAAGCSRATLYRYFDSREALRTAYVHRETRRLGREI
Mb2274c|M.bovis_AF2122/97 VDYGVDRVTLAEIARRAGVSRPTVYRRWPDTRSIMASMLTSHIAAVLREV
MLBr_02568|M.leprae_Br4923 SVNGYHKTSMDAIAAEAQISKPMLYLYYGSKEDLFGACLNREMSRFIAMV
. : :* * *:. :* : : . .
MMAR_0287|M.marinum_M NQATNGHNPR-EAVIEAFTLGVRLIQDSPLYSRIAESEP-ELFGMFSRSH
MUL_4837|M.ulcerans_Agy99 NQATNGHNPR-EAVIEAFTLGVRLIRDSPLYSRIAESEP-ELFGMFSRSH
MAV_5227|M.avium_104 DQATAGCDPQ-QAVIEAFALGVRLVKNSALYSRIAESEP-ELFGLFSRSQ
Mflv_0059|M.gilvum_PYR-GCK ATELKQAGPQSNYYVEAFTLSILKFRGHRVLHRMITEEPGLVLELASLYY
Mvan_0855|M.vanbaalenii_PYR-1 AAELKTAGPQSNYYVEAFTLSILKFRRHRVLHQMIIDEPGLVLELAGRYH
MSMEG_0962|M.smegmatis_MC2_155 AAELKDAKPQSNIYVEAFTLSILRFRRHRVLNQMMKDEPALVLELAHRHY
TH_2255|M.thermoresistible__bu AAELKHSGPQGDYYVEAFTLAILKFRRHRVLHRMITDEPGFILHLAQQHW
MAB_2152|M.abscessus_ATCC_1997 QAVLAPLSNAEDRMVEAFVMGMREARHHPLVAALKEFDS---ESFSRNVF
Rv1255c|M.tuberculosis_H37Rv MVKIADVVEPAERLLVSITTTLRMVRDNPALAAWFTTTR----PPIGGEM
Mb2274c|M.bovis_AF2122/97 PLDGDD----REALVKQIVAVADRLRGDDLIMSVMHSEL--ARVYITERL
MLBr_02568|M.leprae_Br4923 RADIDFTQSPKDLLRNTIVSFLRYIDANRASWIVMYIQA-MSLPAFAQTV
: :.
MMAR_0287|M.marinum_M VFPIGQFADGIAHTLRRCGADAP-DADLANIADILLRVAVGIIMFPTER-
MUL_4837|M.ulcerans_Agy99 VFPIGQFADGIAHTLRRCGADAP-DADLANIADILLRVAVGIIMFPTER-
MAV_5227|M.avium_104 VFPIRQFADGIAHTLRRCGAEQA-EPDLDNIADILLRVALGIIVFPTDR-
Mflv_0059|M.gilvum_PYR-GCK RAAIERMAEALRVIFPPGFAERIGADAVDELADTILRYATMVLLLPSAQP
Mvan_0855|M.vanbaalenii_PYR-1 RAAIDRMAAALRVIFPPGFAERIGPAAVDELADCILRYAAMVLLLPSAQP
MSMEG_0962|M.smegmatis_MC2_155 GAAIERMAAALRVIFPEGFADRIGEAAVNDLADTILRYALMALLIPSVEP
TH_2255|M.thermoresistible__bu GAAVERMAEALRVIFPAGFAERIGEAAVIEFADTILRYAAMALLLPSVQP
MAB_2152|M.abscessus_ATCC_1997 DVNTAGYQGLLAVIAELLSDDSYPVPAVKRALDLALRLTSTFLVNPSDLL
Rv1255c|M.tuberculosis_H37Rv AGRSEVIAALAAAFLNSLGPDDP--TTVERRARWVVRMLTSLLMFPGRD-
Mb2274c|M.bovis_AF2122/97 GTSQQVLIEGLAARLTVAQRSGSVRSGDARRLATMVLLIAQSTIQSADIV
MLBr_02568|M.leprae_Br4923 REARDQITELVAGLMRVGTRSSRPDHEYEIMAGALVGAGEAMATRLTTGD
. :
MMAR_0287|M.marinum_M LDTSDDAAVREYAARYLIPIITL-----------
MUL_4837|M.ulcerans_Agy99 LDTSDDAAVREYAARYLIPIITL-----------
MAV_5227|M.avium_104 LDTADPAAVRDYAARYLVPIIGR-----------
Mflv_0059|M.gilvum_PYR-GCK LETAD--DIRAFARHHFLPSLPEALRSVPA----
Mvan_0855|M.vanbaalenii_PYR-1 LETAD--DVRAFARQHFLPSLPAALRTVPA----
MSMEG_0962|M.smegmatis_MC2_155 LETAD--DIRSFATRHFLPSLPVSLRVVPA----
TH_2255|M.thermoresistible__bu LDTAD--DIRAFATRHFLPSLPAALHTGSA----
MAB_2152|M.abscessus_ATCC_1997 PTDTDT-NTREFAIRYLLPLMRAAR---------
Rv1255c|M.tuberculosis_H37Rv -EADERAMIAEFVVPIVTPASAAARKAGHPGPE-
Mb2274c|M.bovis_AF2122/97 DSILDSAALATELTHALNGYLC------------
MLBr_02568|M.leprae_Br4923 IAVDEAAELMINLFWHGLKGAPADRDFGPSIVAG
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