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MRKALTREELQAQTRDLVLSAAERVFLQRGFHATTVAQIAAEAGRTQGSIYSNFESKDALCQQLLRNHYE GWLSQVALAVMAAENTPAKLDIVESKWRVMSAETDWIGLTAEYLLAVRHDPQQAQLIRENVAALQAGAKA VFAGQLEAEGFAVQDHPMLDDAVAAIVATGMGLVVNHTLGLVEPDQSTSVFMQTLETWRDRLIA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_0138 | - | - | 100% (204) | TetR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_0145c | - | 7e-24 | 33.33% (198) | TetR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_3437c | - | 8e-15 | 30.69% (189) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1561 | - | 3e-11 | 44.74% (76) | transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_2460 | - | 2e-12 | 28.80% (184) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv1534 | - | 3e-11 | 44.74% (76) | transcriptional regulator |
| M. leprae Br4923 | MLBr_02677 | - | 1e-07 | 29.67% (91) | putative TetR-family transcriptional regulator |
| M. marinum M | MMAR_4631 | - | 8e-10 | 26.79% (168) | transcriptional regulatory protein |
| M. avium 104 | MAV_1611 | - | 3e-16 | 30.00% (200) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_6807 | - | 3e-14 | 28.18% (181) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_2070 | - | 1e-07 | 36.99% (73) | PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY |
| M. ulcerans Agy99 | MUL_4890 | - | 4e-08 | 27.44% (164) | transcriptional regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_4194 | - | 2e-12 | 32.37% (139) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1561|M.bovis_AF2122/97 MSRASARRRRAVSDEDKSQRRDEILAAAKIVFAHKGFHATTVADIAKQAG
Rv1534|M.tuberculosis_H37Rv MSRASARRRRAVSDEDKSQRRDEILAAAKIVFAHKGFHATTVADIAKQAG
Mflv_2460|M.gilvum_PYR-GCK ------MVERWTRERRLEHTRSVLLDAAEEVFAEKGFTPATLDDIARAAG
Mvan_4194|M.vanbaalenii_PYR-1 ------MAERWTRERRLEHTRSVLLDAAEEVFAEKGFTPATLDDIARTAG
MSMEG_6807|M.smegmatis_MC2_155 ------MVERWTRERRLEHTRSLLLDAAENVFSEKGFTAATLDDIAFAAG
MLBr_02677|M.leprae_Br4923 -----MESQRRTQEERSTATRDALTLARHRLWRLRGYAEVGTPEIAKEAD
MUL_4890|M.ulcerans_Agy99 -----MESKRRTQEERSAATREALITAARKLWGSRGYAEVGTPEIAAEAG
MAB_0138|M.abscessus_ATCC_1997 ------MRKALTREELQAQTRDLVLSAAERVFLQRGFHATTVAQIAAEAG
MAV_1611|M.avium_104 MLLGMSPVKPLRSRPTRGEVRDRILDAAAKVFAAEGFAGATIDAIGQAAG
TH_2070|M.thermoresistible__bu -----------MTNSGPPTRRDELLELAAQMFAERGLKATTVRDIADSAG
MMAR_4631|M.marinum_M MTPPANTATPARVTKRRAETRARLVDAAFRVFADKGFGHVRIEDVCAAAG
* : :: .* . : *.
Mb1561|M.bovis_AF2122/97 LAYGLIYWYFDSKDDLFHALMAGEEEALRAHVAAELARVGGSTEAPLRAL
Rv1534|M.tuberculosis_H37Rv LAYGLIYWYFDSKDDLFHALMAGEEEALRAHVAAELARVGGSTEAPLRAL
Mflv_2460|M.gilvum_PYR-GCK YTKGAIYKHFDTKEELFLAVSDRYWRRYFDNFAEVMSS-ASRVGADELDE
Mvan_4194|M.vanbaalenii_PYR-1 YTKGAIYKHFATKEDLFLAVSDRYWRRYFDNFAEVMAS-ASRVGAHELDE
MSMEG_6807|M.smegmatis_MC2_155 YTKGAIYKHFATKEDLFLAVSDRYWRRYFDNFAEVMAS-AASVGARELDE
MLBr_02677|M.leprae_Br4923 TTRGAVYHQFTDKAALFRDVVETVEQDAMAQIASVVASSGAKTPVDAIRA
MUL_4890|M.ulcerans_Agy99 VTRGAMYHQFADKAALFGEVVEAVEQDVMTRMATSVTTSGAATPADAIRA
MAB_0138|M.abscessus_ATCC_1997 RTQGSIYSNFESKDALCQQLLRNHYEGWLSQVALAVMAAENTPAKLDIVE
MAV_1611|M.avium_104 FTKGAVYSNFESKDELFLALLDREFELRGQQIAIALDRSAGDTTAAAREV
TH_2070|M.thermoresistible__bu ILSGSLYHHFASKEEMVDEVLRGFLDWLFDRYRSIVETEPNPLERFKGLF
MMAR_4631|M.marinum_M YTRGAFYSQFDSLEELFFTLYDQRATLISEQVGTAMASVDDPTDVPGTVD
* .* * : : . :
Mb1561|M.bovis_AF2122/97 LQAAVQATFEFFETDKATVKLLFRDAYALGGRFEEHLGGIYERFIDDIEA
Rv1534|M.tuberculosis_H37Rv LQAAVQATFEFFETDKATVKLLFRDAYALGGRFEEHLGGIYERFIDDIEA
Mflv_2460|M.gilvum_PYR-GCK IAERWRQLSIDRGAEHAALGLEFTLYLLRNPEARERVEAKRAEVVDQLAE
Mvan_4194|M.vanbaalenii_PYR-1 IAERWRQLSIDRGADHAALGLEFTLYLLRNPDARERVAAKRAEVVDQLAK
MSMEG_6807|M.smegmatis_MC2_155 IAKRWRQLSVDRGAEQAALGLEFTLYLKRNPEARDRVAAKRSEVVAQLTA
MLBr_02677|M.leprae_Br4923 KVDAWLEGLAD--PQVRQLILLYAPSVLGWAAFRDVAQHYSLGMTEQQLL
MUL_4890|M.ulcerans_Agy99 AVDAWLEVSGD--PEVRQLILLDAPAVLGWAGFCDVAQRYSLGMTEQ-LI
MAB_0138|M.abscessus_ATCC_1997 SKWRVMSAETDWIGLTAEYLLAVRHDPQQAQLIRENVAALQAGAKAVFAG
MAV_1611|M.avium_104 SRSVLDSVRDH--SDYYVLLVEYWLRAQRDPQLRERLIERRRAAADQALH
TH_2070|M.thermoresistible__bu MASFEAIEHRHAQVVIYQDEAKRLSSQPRFAYVEQRNREQRKMWVDVLTQ
MMAR_4631|M.marinum_M RIASTLLLDRDWLLIKTDFLMHAARHPDLAQRLAAHRAQLRAAVEDRLAG
Mb1561|M.bovis_AF2122/97 VVVAAQRRGE----VVEAPSRMAAYTLAALVGQLAHRRLNTDDNVT----
Rv1534|M.tuberculosis_H37Rv VVVAAQRRGE----VVEAPSRMAAYTLAALVGQLAHRRLNTDDNVT----
Mflv_2460|M.gilvum_PYR-GCK FIVEGMSQLG-------ATLLIEPSTFARALVATSDSVVLGSQLDA----
Mvan_4194|M.vanbaalenii_PYR-1 FINEGMTRLG-------ASLLISPLTFAQALVATSDSVVLASQLDD----
MSMEG_6807|M.smegmatis_MC2_155 FIVASIEKLG-------ATLLISPETFAHALVATSDSVVLSSELDN----
MLBr_02677|M.leprae_Br4923 SEASRARQLA----QPLDHVLIGKLYESAMAIRRHHRLPEASPARNQTGA
MUL_4890|M.ulcerans_Agy99 TEAIRAGQLDRHPVRPLAHVLIGALDEAAMFIATAD-----DPKR-----
MAB_0138|M.abscessus_ATCC_1997 QLEAEGFAVQD---HPMLDDAVAAIVATGMGLVVNHTLGLVEPDQS----
MAV_1611|M.avium_104 IVESTDTVPGD-----RRLTDIAQLVVTLNLGVAMEEVLRPGTINP----
TH_2070|M.thermoresistible__bu GIEEGYFRSD-------IDVDLVYRFIRDTTWVSVRWYRPGGPLTA----
MMAR_4631|M.marinum_M SDVELPAAIG-------SVADAARAVVAAYDGVSIQLLLDGDQDAA----
Mb1561|M.bovis_AF2122/97 ----AAQVADFVVSLVLDGLRPRALAVGARGGRAART----------
Rv1534|M.tuberculosis_H37Rv ----AAQVADFVVSLVLDGLRPRALAVGARGGRAART----------
Mflv_2460|M.gilvum_PYR-GCK -----VDLYRPMVEMYVSVIKLPD-----------------------
Mvan_4194|M.vanbaalenii_PYR-1 -----IDLYRPVVEMYTSVIKLPD-----------------------
MSMEG_6807|M.smegmatis_MC2_155 -----VDLYRPMVEMYASMIKLPT-----------------------
MLBr_02677|M.leprae_Br4923 APTHREHVARPSCEALTRHIRHRSTRTRSHRGKRGELLPRAATSSLL
MUL_4890|M.ulcerans_Agy99 -------ARRESRQVLRRLIDG--------------MLND-------
MAB_0138|M.abscessus_ATCC_1997 -----TSVFMQTLETWRDRLIA-------------------------
MAV_1611|M.avium_104 ------DLLAQLITALLESIPV-------------------------
TH_2070|M.thermoresistible__bu -----EEVGRQYLSIVLGGITAGAN----------------------
MMAR_4631|M.marinum_M ---------RAWLSQLLGVVLIR------------------------
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