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TTPEATDAKPVGKEEVVEAVLTAASALFAEKGPAATSIREVATRAGVNHGLVHRHFGSKRQLLAATLQHL ADTAAAVREAGAPIEELEAAHDLQLRVMVRSTLDGFPIEELQERKPGMAWLLEQVRPGHADERDARLAAA HAIALQLGWRLMGPSLRAGFGLDDMSDADMRAEIAQQIAKIVTPH*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_0085c | - | - | 100% (186) | putative transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_4946 | - | 3e-08 | 30.20% (149) | putative transcriptional regulator, TetR |
| M. abscessus ATCC 19977 | MAB_0835c | - | 3e-08 | 30.83% (120) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3439c | - | 1e-47 | 48.94% (188) | transcriptional regulatory protein |
| M. gilvum PYR-GCK | Mflv_5008 | - | 3e-07 | 37.97% (79) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv3405c | - | 1e-47 | 48.94% (188) | transcriptional regulatory protein |
| M. leprae Br4923 | MLBr_00815 | - | 6e-06 | 35.48% (62) | putative TetR-family transcriptional regulator |
| M. marinum M | MMAR_1142 | - | 3e-46 | 53.94% (165) | transcriptional regulator |
| M. avium 104 | MAV_4351 | - | 7e-45 | 51.50% (167) | putative HTH-type transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_0180 | - | 2e-35 | 53.10% (145) | putative HTH-type transcriptional regulator |
| M. thermoresistible (build 8) | TH_0452 | - | 3e-07 | 37.68% (69) | PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY |
| M. ulcerans Agy99 | MUL_0905 | - | 1e-49 | 54.29% (175) | transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_1492 | - | 7e-09 | 40.40% (99) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3439c|M.bovis_AF2122/97 ---------------------MTTRPATDRRKMPTGREEVAAAILQAATD
Rv3405c|M.tuberculosis_H37Rv ---------------------MTTRPATDRRKMPTGREEVAAAILQAATD
MMAR_1142|M.marinum_M -------------------------------------------MLEAAAD
MUL_0905|M.ulcerans_Agy99 ---------------------MTTGSAIRSRKTPTGREEVAAAVLEAAAD
MAV_4351|M.avium_104 ---------------------------------------MAAAILEAATD
MAB_0085c|M.abscessus_ATCC_199 ---------------------MTTPEATDAK--PVGKEEVVEAVLTAASA
MSMEG_0180|M.smegmatis_MC2_155 ---------------------MTTASGGQRD----AGARIRPVVLTHAAD
MLBr_00815|M.leprae_Br4923 MNNLAKAAQRRTVRPIDRGRLSDDIATPNQRSNRLSRDKRRGQLLIVASD
TH_0452|M.thermoresistible__bu MSEVADTTARQEITPTNGGTTSGAAAGANRRGNRLPRDERRNQLLIAASE
Mflv_5008|M.gilvum_PYR-GCK ---------------------MTAPVRGRPR-----DPDADRAILQAALD
Mvan_1492|M.vanbaalenii_PYR-1 -------------------------MTPPDRPVRADAARNRALLLAAAEE
:* *
Mb3439c|M.bovis_AF2122/97 LFAERGPAATSIRDIAARSKVNHGLVFRHFGTKDQLVGAVLDHLGTKLT-
Rv3405c|M.tuberculosis_H37Rv LFAERGPAATSIRDIAARSKVNHGLVFRHFGTKDQLVGAVLDHLGTKLT-
MMAR_1142|M.marinum_M LFAERGPAATSIRDIAARSKVNHGLVFRHFGAKEQLVGAVLDYLGTHLT-
MUL_0905|M.ulcerans_Agy99 LFAERGPAATSIRDIAARSKVNHGLVFRHFGAKEQLVGAVLDYLGTHLT-
MAV_4351|M.avium_104 LFAERGPAATSIRDIAARCGVNHGLVFRHFGTKEQLVGAVLDHLGANLS-
MAB_0085c|M.abscessus_ATCC_199 LFAEKGPAATSIREVATRAGVNHGLVHRHFGSKRQLLAATLQHLADTAA-
MSMEG_0180|M.smegmatis_MC2_155 LFAERGPAATSLRDVAERSGVNAGLIFRHIGNKEALVAAVLDFLADELV-
MLBr_00815|M.leprae_Br4923 VFVDHGYHAAGMDEIADRAGVSKPVLYQHFSSKLELYLAVLERHMNNLVS
TH_0452|M.thermoresistible__bu VFVDRGYHAAGMDEIAERAGVSKPVLYQHFSSKLELYLAVLQRHVDNLVS
Mflv_5008|M.gilvum_PYR-GCK LFIERGVEGSSIEQIAKRAGVGKPTVYRRWGTKEELIAAAMETLVAEEVG
Mvan_1492|M.vanbaalenii_PYR-1 EFAERGP-SASVADIARRAGVAKGTVFRHFPTKEDLIAAIVSEHIAVLA-
* ::* .:.: ::* *. * :.:: * * * :.
Mb3439c|M.bovis_AF2122/97 ----RLLHSEAPADIIERALDRHGRVLAR------------ALLDGYPVG
Rv3405c|M.tuberculosis_H37Rv ----RLLHSEAPADIIERALDRHGRVLAR------------ALLDGYPVG
MMAR_1142|M.marinum_M ----ELLRAGTPADDLERALDRQMRVWAR------------TLLDGYPAE
MUL_0905|M.ulcerans_Agy99 ----ELLRAGTPADDLERALDRQMRVWAR------------TLLDGYPAE
MAV_4351|M.avium_104 ----ALLATDTPAEVVEQSLDRQMRVMAR------------TVLDGYPAG
MAB_0085c|M.abscessus_ATCC_199 ----AVREAGAPIEELEAAHDLQLRVMVR------------STLDGFPIE
MSMEG_0180|M.smegmatis_MC2_155 ----TARGTDAPEEVIEAHVERSWKVIAR------------ALLDGYDVG
MLBr_00815|M.leprae_Br4923 SVQQALRTTTNNRQRLHAAVQAFFDFIEHDGQGYRLIFENDNITEPRVAA
TH_0452|M.thermoresistible__bu GVRQALRTTTDNRQRLRAAVQAFFDFIEHDGQGYRLIFENDYVTEPQVAA
Mflv_5008|M.gilvum_PYR-GCK WTSPEAIETRSPHVLVEAAIDSAAAATAAPYYRALVARVYGSAVSHPELM
Mvan_1492|M.vanbaalenii_PYR-1 ----AAARRLADSPDPGAALLEFLTIAAD-------------QRQRHDLT
.
Mb3439c|M.bovis_AF2122/97 QLQQRFPNVAELLDAVRPRYD--SDLGARLAVAHALALQFGWRLFAPMLR
Rv3405c|M.tuberculosis_H37Rv QLQQRFPNVAELLDAVRPRYD--SDLGARLAVAHALALQFGWRLFAPMLR
MMAR_1142|M.marinum_M QLQTRFPNVAELLGQVRVHHG--DDTTARLAVANAIALRLGWRLFEPMLR
MUL_0905|M.ulcerans_Agy99 QLQTRFPNVAELLGQVRVHHG--DDTTARLAVANAIALCLGWRLFEPMLR
MAV_4351|M.avium_104 QLQKRFPNIATLLDGVRPLHD--DELHARLAVANALALQFGWRLFAPILR
MAB_0085c|M.abscessus_ATCC_199 ELQERKPGMAWLLEQVRPGHA--DERDARLAAAHAIALQLGWRLMGPSLR
MSMEG_0180|M.smegmatis_MC2_155 ALQHRFPVVEELVEAARQRHQ--DDHAARAATADAIALQLGWRLFGPFLR
MLBr_00815|M.leprae_Br4923 QVRVATESCIDAVFALISADSRLDPHRARMVAVGLVGISVDCARYWLDTN
TH_0452|M.thermoresistible__bu QVKVATEACTDAVFDLISQDSGLEAHRARMIAVGLVAISVDCARYWLHAD
Mflv_5008|M.gilvum_PYR-GCK TVYWDRYILPRRVQATRLLER--ARELGTVAADTDLDVAIDMMVGAITYR
Mvan_1492|M.vanbaalenii_PYR-1 FLQSASDGDPRVTEVRDALHANLETLVDRARTSGAIRADITEADVFLMMC
: . : .
Mb3439c|M.bovis_AF2122/97 SATGIDELTGDELRLSVNDAVARILEPH----------------
Rv3405c|M.tuberculosis_H37Rv SATGIDELTGDELRLSVNDAVARILEPH----------------
MMAR_1142|M.marinum_M SATGLDELADADLRQAVTDEVARIIEPSGRG-------------
MUL_0905|M.ulcerans_Agy99 SATGLDELADADLRQAVTDEVARIIEPSGRG-------------
MAV_4351|M.avium_104 AATGIEELTDAELRRAAGAEVERILRSPDPH-------------
MAB_0085c|M.abscessus_ATCC_199 AGFGLDDMSDADMRAEIAQQIAKIVTPH----------------
MSMEG_0180|M.smegmatis_MC2_155 AATGLDDNHPPAD-------------------------------
MLBr_00815|M.leprae_Br4923 RPISKSDAVEGTVQFAWGGLSHVPLTRL----------------
TH_0452|M.thermoresistible__bu RPISKEDAVEGTVQFAWGGLSHVPLTRS----------------
Mflv_5008|M.gilvum_PYR-GCK VLRPNPPDVDEMRRYLREVYRQAGLLPPG---------------
Mvan_1492|M.vanbaalenii_PYR-1 APIHIVENLPAPAPLLWQRYLAIIFDGLRPDGAHPLPQPAPAAP