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TTASGGQRDAGARIRPVVLTHAADLFAERGPAATSLRDVAERSGVNAGLIFRHIGNKEALVAAVLDFLAD ELVTARGTDAPEEVIEAHVERSWKVIARALLDGYDVGALQHRFPVVEELVEAARQRHQDDHAARAATADA IALQLGWRLFGPFLRAATGLDDNHPPAD*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_0180 | - | - | 100% (169) | putative HTH-type transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_3807 | - | 2e-10 | 37.59% (141) | TetR-type regulator |
| M. smegmatis MC2 155 | MSMEG_1500 | - | 4e-08 | 36.17% (94) | TetR family protein transcriptional regulatory protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3439c | - | 3e-43 | 56.38% (149) | transcriptional regulatory protein |
| M. gilvum PYR-GCK | Mflv_2369 | - | 3e-08 | 30.77% (117) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv3405c | - | 3e-43 | 56.38% (149) | transcriptional regulatory protein |
| M. leprae Br4923 | MLBr_00316 | - | 6e-06 | 31.37% (102) | putative TetR/AcrR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_0085c | - | 1e-35 | 53.10% (145) | putative transcriptional regulator |
| M. marinum M | MMAR_1142 | - | 9e-40 | 57.93% (145) | transcriptional regulator |
| M. avium 104 | MAV_4351 | - | 3e-42 | 54.36% (149) | putative HTH-type transcriptional regulator |
| M. thermoresistible (build 8) | TH_2719 | - | 2e-08 | 38.46% (78) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_0905 | - | 1e-39 | 56.38% (149) | transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_1492 | - | 6e-09 | 35.11% (131) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3439c|M.bovis_AF2122/97 -------MTTRPATDRRKMPTGREEVAAAILQAATDLFAERGPAATSIRD
Rv3405c|M.tuberculosis_H37Rv -------MTTRPATDRRKMPTGREEVAAAILQAATDLFAERGPAATSIRD
MMAR_1142|M.marinum_M -----------------------------MLEAAADLFAERGPAATSIRD
MUL_0905|M.ulcerans_Agy99 -------MTTGSAIRSRKTPTGREEVAAAVLEAAADLFAERGPAATSIRD
MAV_4351|M.avium_104 -------------------------MAAAILEAATDLFAERGPAATSIRD
MAB_0085c|M.abscessus_ATCC_199 -------MTTPEATDAK--PVGKEEVVEAVLTAASALFAEKGPAATSIRE
MSMEG_0180|M.smegmatis_MC2_155 -------MTTASGGQRD----AGARIRPVVLTHAADLFAERGPAATSLRD
MLBr_00316|M.leprae_Br4923 MSVPRSGLSVQMAQPARPLRADAARNRARILGVAYEAFATEGLSVP-IDE
Mvan_1492|M.vanbaalenii_PYR-1 -----------MTPPDRPVRADAARNRALLLAAAEEEFAERGPSAS-VAD
TH_2719|M.thermoresistible__bu --------------MASRRAQISEESRRLLIAAATELFAEQGFRRTTFAD
Mflv_2369|M.gilvum_PYR-GCK --------------MSGRIGSEGPRNIERIRAAALHSFGEHGAAATTLRG
: * *. .* . .
Mb3439c|M.bovis_AF2122/97 IAARSKVNHGLVFRHFGTKDQLVGAVL----DHLGTKLTRLLHSEAPADI
Rv3405c|M.tuberculosis_H37Rv IAARSKVNHGLVFRHFGTKDQLVGAVL----DHLGTKLTRLLHSEAPADI
MMAR_1142|M.marinum_M IAARSKVNHGLVFRHFGAKEQLVGAVL----DYLGTHLTELLRAGTPADD
MUL_0905|M.ulcerans_Agy99 IAARSKVNHGLVFRHFGAKEQLVGAVL----DYLGTHLTELLRAGTPADD
MAV_4351|M.avium_104 IAARCGVNHGLVFRHFGTKEQLVGAVL----DHLGANLSALLATDTPAEV
MAB_0085c|M.abscessus_ATCC_199 VATRAGVNHGLVHRHFGSKRQLLAATL----QHLADTAAAVREAGAPIEE
MSMEG_0180|M.smegmatis_MC2_155 VAERSGVNAGLIFRHIGNKEALVAAVL----DFLADELVTARGTDAPEEV
MLBr_00316|M.leprae_Br4923 IARRAGVGAGTVYRHFPTKEALCAAVIGDRMPHLVDDGYVLLKSAGPGEA
Mvan_1492|M.vanbaalenii_PYR-1 IARRAGVAKGTVFRHFPTKEDLIAAIVSEHIAVLAAAARRLADSPDPGAA
TH_2719|M.thermoresistible__bu IAERSGISRGSIPWHFGNKDGLLRAVI----EDFIAGVIELDASEQTLSE
Mflv_2369|M.gilvum_PYR-GCK VAAAAGVSLGLVQHHFATKAGLIEAVDDYVMKLVVTTMSRPLP-EPPVDS
:* . : * : *: * * * . .
Mb3439c|M.bovis_AF2122/97 IERALDRHGR---VLARALLDGYPVGQLQQRFPNVAELLDAVRPRYDSDL
Rv3405c|M.tuberculosis_H37Rv IERALDRHGR---VLARALLDGYPVGQLQQRFPNVAELLDAVRPRYDSDL
MMAR_1142|M.marinum_M LERALDRQMR---VWARTLLDGYPAEQLQTRFPNVAELLGQVRVHHGDDT
MUL_0905|M.ulcerans_Agy99 LERALDRQMR---VWARTLLDGYPAEQLQTRFPNVAELLGQVRVHHGDDT
MAV_4351|M.avium_104 VEQSLDRQMR---VMARTVLDGYPAGQLQKRFPNIATLLDGVRPLHDDEL
MAB_0085c|M.abscessus_ATCC_199 LEAAHDLQLR---VMVRSTLDGFPIEELQERKPGMAWLLEQVRPGHADER
MSMEG_0180|M.smegmatis_MC2_155 IEAHVERSWK---VIARALLDGYDVGALQHRFPVVEELVEAARQRHQDDH
MLBr_00316|M.leprae_Br4923 LFTYLRSLVLHWGATDRGLVDALAGAGGIDILGVAPDAEDAFLTILSD-L
Mvan_1492|M.vanbaalenii_PYR-1 LLEFLTIAADQRQRHDLTFLQSASDGD-----PRVTEVRDALHANLET-L
TH_2719|M.thermoresistible__bu GLDRIRDYVRRPTTRLLITLVAEAVEPDSPVHAFYAQLHDTLRKWLSDWI
Mflv_2369|M.gilvum_PYR-GCK VAEIGNRITR--MFAEEPDVVAYLGRALADGSPIGTRIFDTLLASGIARW
: .
Mb3439c|M.bovis_AF2122/97 GARLAVAHAL-ALQFGWRLFAPMLRSATGIDELTGDELRLSVNDAVARIL
Rv3405c|M.tuberculosis_H37Rv GARLAVAHAL-ALQFGWRLFAPMLRSATGIDELTGDELRLSVNDAVARIL
MMAR_1142|M.marinum_M TARLAVANAI-ALRLGWRLFEPMLRSATGLDELADADLRQAVTDEVARII
MUL_0905|M.ulcerans_Agy99 TARLAVANAI-ALCLGWRLFEPMLRSATGLDELADADLRQAVTDEVARII
MAV_4351|M.avium_104 HARLAVANAL-ALQFGWRLFAPILRAATGIEELTDAELRRAAGAEVERIL
MAB_0085c|M.abscessus_ATCC_199 DARLAAAHAI-ALQLGWRLMGPSLRAGFGLDDMSDADMRAEIAQQIAKIV
MSMEG_0180|M.smegmatis_MC2_155 AARAATADAI-ALQLGWRLFGPFLRAATGLDDNHPPAD------------
MLBr_00316|M.leprae_Br4923 LYAAQYAGTA-RTDVGVREVKSILVG----CQAMEAYNSALAERVTDVVV
Mvan_1492|M.vanbaalenii_PYR-1 VDRARTSGAI-RADITEADVFLMMCAPIHIVENLPAPAPLLWQRYLAIIF
TH_2719|M.thermoresistible__bu DDKDIPPGVS-RENFVTVLIGAVIGVHQQWRVAPHHVDLDACFAALKQLA
Mflv_2369|M.gilvum_PYR-GCK QQRIDRGEVRPDIDITWAAINGLVLALGAISLRHHLDRHLSEPFTTPRQL
. . . :
Mb3439c|M.bovis_AF2122/97 EPH----------------
Rv3405c|M.tuberculosis_H37Rv EPH----------------
MMAR_1142|M.marinum_M EPSGRG-------------
MUL_0905|M.ulcerans_Agy99 EPSGRG-------------
MAV_4351|M.avium_104 RSPDPH-------------
MAB_0085c|M.abscessus_ATCC_199 TPH----------------
MSMEG_0180|M.smegmatis_MC2_155 -------------------
MLBr_00316|M.leprae_Br4923 DGLRAAR------------
Mvan_1492|M.vanbaalenii_PYR-1 DGLRPDGAHPLPQPAPAAP
TH_2719|M.thermoresistible__bu SGD----------------
Mflv_2369|M.gilvum_PYR-GCK DRWQRAVDTLLREGLFRRE