For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
MTTRPATDRRKMPTGREEVAAAILQAATDLFAERGPAATSIRDIAARSKVNHGLVFRHFGTKDQLVGAVL DHLGTKLTRLLHSEAPADIIERALDRHGRVLARALLDGYPVGQLQQRFPNVAELLDAVRPRYDSDLGARL AVAHALALQFGWRLFAPMLRSATGIDELTGDELRLSVNDAVARILEPH
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3439c | - | - | 100% (188) | transcriptional regulatory protein |
| M. bovis AF2122 / 97 | Mb1711c | - | 9e-08 | 41.18% (68) | hypothetical protein Mb1711c |
| M. bovis AF2122 / 97 | Mb1047 | - | 4e-06 | 44.90% (49) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_5008 | - | 2e-09 | 35.71% (98) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv3405c | - | 1e-104 | 100.00% (188) | transcriptional regulatory protein |
| M. leprae Br4923 | MLBr_00316 | - | 6e-05 | 36.17% (94) | putative TetR/AcrR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_0085c | - | 1e-47 | 48.94% (188) | putative transcriptional regulator |
| M. marinum M | MMAR_1142 | - | 3e-62 | 72.73% (165) | transcriptional regulator |
| M. avium 104 | MAV_4351 | - | 9e-66 | 71.68% (173) | putative HTH-type transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_0180 | - | 5e-43 | 56.38% (149) | putative HTH-type transcriptional regulator |
| M. thermoresistible (build 8) | TH_2719 | - | 3e-08 | 36.25% (80) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_0905 | - | 1e-69 | 72.19% (187) | transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_1492 | - | 9e-09 | 37.62% (101) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3439c|M.bovis_AF2122/97 -------MTTRPATDRRKMPTGREEVAAAILQAATDLFAERGPAATSIRD
Rv3405c|M.tuberculosis_H37Rv -------MTTRPATDRRKMPTGREEVAAAILQAATDLFAERGPAATSIRD
MMAR_1142|M.marinum_M -----------------------------MLEAAADLFAERGPAATSIRD
MUL_0905|M.ulcerans_Agy99 -------MTTGSAIRSRKTPTGREEVAAAVLEAAADLFAERGPAATSIRD
MAV_4351|M.avium_104 -------------------------MAAAILEAATDLFAERGPAATSIRD
MAB_0085c|M.abscessus_ATCC_199 -------MTTPEATDAK--PVGKEEVVEAVLTAASALFAEKGPAATSIRE
MSMEG_0180|M.smegmatis_MC2_155 -------MTTASGGQRD----AGARIRPVVLTHAADLFAERGPAATSLRD
MLBr_00316|M.leprae_Br4923 MSVPRSGLSVQMAQPARPLRADAARNRARILGVAYEAFATEGLSVP-IDE
Mvan_1492|M.vanbaalenii_PYR-1 -----------MTPPDRPVRADAARNRALLLAAAEEEFAERGPSAS-VAD
Mflv_5008|M.gilvum_PYR-GCK -----------MTAPVRGRPRDPDADR-AILQAALDLFIERGVEGSSIEQ
TH_2719|M.thermoresistible__bu --------------MASRRAQISEESRRLLIAAATELFAEQGFRRTTFAD
:: * * .* . . :
Mb3439c|M.bovis_AF2122/97 IAARSKVNHGLVFRHFGTKDQLVGAVL-----DHLGTKLTRLLHSEAPAD
Rv3405c|M.tuberculosis_H37Rv IAARSKVNHGLVFRHFGTKDQLVGAVL-----DHLGTKLTRLLHSEAPAD
MMAR_1142|M.marinum_M IAARSKVNHGLVFRHFGAKEQLVGAVL-----DYLGTHLTELLRAGTPAD
MUL_0905|M.ulcerans_Agy99 IAARSKVNHGLVFRHFGAKEQLVGAVL-----DYLGTHLTELLRAGTPAD
MAV_4351|M.avium_104 IAARCGVNHGLVFRHFGTKEQLVGAVL-----DHLGANLSALLATDTPAE
MAB_0085c|M.abscessus_ATCC_199 VATRAGVNHGLVHRHFGSKRQLLAATL-----QHLADTAAAVREAGAPIE
MSMEG_0180|M.smegmatis_MC2_155 VAERSGVNAGLIFRHIGNKEALVAAVL-----DFLADELVTARGTDAPEE
MLBr_00316|M.leprae_Br4923 IARRAGVGAGTVYRHFPTKEALCAAVIG-DRMPHLVDDGYVLLKSAGPGE
Mvan_1492|M.vanbaalenii_PYR-1 IARRAGVAKGTVFRHFPTKEDLIAAIVS-EHIAVLAAAARRLADSPDPGA
Mflv_5008|M.gilvum_PYR-GCK IAKRAGVGKPTVYRRWGTKEELIAAAMETLVAEEVGWTSPEAIETRSPHV
TH_2719|M.thermoresistible__bu IAERSGISRGSIPWHFGNKDGLLRAVI--------EDFIAGVIELDASEQ
:* *. : : : * * * : .
Mb3439c|M.bovis_AF2122/97 IIERALDRHGR---VLARALLDGYPVGQLQQRFPNVAELLD---AVRPRY
Rv3405c|M.tuberculosis_H37Rv IIERALDRHGR---VLARALLDGYPVGQLQQRFPNVAELLD---AVRPRY
MMAR_1142|M.marinum_M DLERALDRQMR---VWARTLLDGYPAEQLQTRFPNVAELLG---QVRVHH
MUL_0905|M.ulcerans_Agy99 DLERALDRQMR---VWARTLLDGYPAEQLQTRFPNVAELLG---QVRVHH
MAV_4351|M.avium_104 VVEQSLDRQMR---VMARTVLDGYPAGQLQKRFPNIATLLD---GVRPLH
MAB_0085c|M.abscessus_ATCC_199 ELEAAHDLQLR---VMVRSTLDGFPIEELQERKPGMAWLLE---QVRPGH
MSMEG_0180|M.smegmatis_MC2_155 VIEAHVERSWK---VIARALLDGYDVGALQHRFPVVEELVE---AARQRH
MLBr_00316|M.leprae_Br4923 ALFTYLRSLVLHWGATDRGLVDALAGAGGIDILGVAPDAED---AFLTIL
Mvan_1492|M.vanbaalenii_PYR-1 ALLEFLTIAADQRQRHDLTFLQSASDGD-----PRVTEVRD---ALHANL
Mflv_5008|M.gilvum_PYR-GCK LVEAAIDSAAAATAAPYYRALVARVYGSAVSHPELMTVYWDRYILPRRVQ
TH_2719|M.thermoresistible__bu TLSEGLDRIRDYVRRPTTRLLITLVAEAVEPDSPVHAFYAQLHDTLRKWL
: :
Mb3439c|M.bovis_AF2122/97 DSDLGARLAVAHALALQFGWRLFAPMLRSATGIDELTGDELRLSVNDAVA
Rv3405c|M.tuberculosis_H37Rv DSDLGARLAVAHALALQFGWRLFAPMLRSATGIDELTGDELRLSVNDAVA
MMAR_1142|M.marinum_M GDDTTARLAVANAIALRLGWRLFEPMLRSATGLDELADADLRQAVTDEVA
MUL_0905|M.ulcerans_Agy99 GDDTTARLAVANAIALCLGWRLFEPMLRSATGLDELADADLRQAVTDEVA
MAV_4351|M.avium_104 DDELHARLAVANALALQFGWRLFAPILRAATGIEELTDAELRRAAGAEVE
MAB_0085c|M.abscessus_ATCC_199 ADERDARLAAAHAIALQLGWRLMGPSLRAGFGLDDMSDADMRAEIAQQIA
MSMEG_0180|M.smegmatis_MC2_155 QDDHAARAATADAIALQLGWRLFGPFLRAATGLDDNHPPAD---------
MLBr_00316|M.leprae_Br4923 SD-LLYAAQYAGTARTDVGVREVKSILVG----CQAMEAYNSALAERVTD
Mvan_1492|M.vanbaalenii_PYR-1 ET-LVDRARTSGAIRADITEADVFLMMCAPIHIVENLPAPAPLLWQRYLA
Mflv_5008|M.gilvum_PYR-GCK ATRLLERARELGTVAADTDLDVAIDMMVGAITYRVLRPNPPDVDEMRRYL
TH_2719|M.thermoresistible__bu SDWIDDKDIPPGVSRENFVTVLIGAVIGVHQQWRVAPHHVDLDACFAALK
. :
Mb3439c|M.bovis_AF2122/97 RILEPH----------------
Rv3405c|M.tuberculosis_H37Rv RILEPH----------------
MMAR_1142|M.marinum_M RIIEPSGRG-------------
MUL_0905|M.ulcerans_Agy99 RIIEPSGRG-------------
MAV_4351|M.avium_104 RILRSPDPH-------------
MAB_0085c|M.abscessus_ATCC_199 KIVTPH----------------
MSMEG_0180|M.smegmatis_MC2_155 ----------------------
MLBr_00316|M.leprae_Br4923 VVVDGLRAAR------------
Mvan_1492|M.vanbaalenii_PYR-1 IIFDGLRPDGAHPLPQPAPAAP
Mflv_5008|M.gilvum_PYR-GCK REVYRQAGLLPPG---------
TH_2719|M.thermoresistible__bu QLASGD----------------