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MEDPAEPPIRMADRQRARRSELVKEEVVEAALAEFSERGYHQTSIAHIAERLGTGHSMFYRYFTNKRDIL EHVVQHATQRTIETLSHTLPGRITSLNEFHDFSVNLGLAYIDLVVADPRLSRLLLQQGAAVDAEMTAQFC GVFDAGAAVLGGLLRDGIESGYVREDIDVEAVADSVVGIPLGILARYGHEPNQDILAARVRATADLVCRG IAP
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_4946 | - | - | 100% (213) | putative transcriptional regulator, TetR |
| M. abscessus ATCC 19977 | MAB_1379c | - | 3e-28 | 34.36% (195) | TetR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_1525c | - | 4e-28 | 36.93% (176) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0237 | - | 2e-08 | 28.14% (167) | TetR/ACRR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_1535 | - | 3e-07 | 26.01% (173) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0232 | - | 2e-08 | 28.14% (167) | TetR/ACRR family transcriptional regulator |
| M. leprae Br4923 | MLBr_01733 | - | 6e-06 | 26.77% (127) | putative TetR-family transcriptional regulator |
| M. marinum M | MMAR_0489 | - | 8e-10 | 28.74% (167) | TetR family transcriptional regulator |
| M. avium 104 | MAV_5138 | - | 5e-09 | 27.61% (163) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_2193 | - | 9e-07 | 26.63% (199) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_0258 | - | 2e-07 | 37.80% (82) | transcriptional repressor, TetR family protein, putative |
| M. ulcerans Agy99 | MUL_1152 | - | 7e-10 | 28.74% (167) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_3467 | - | 1e-08 | 28.66% (164) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0237|M.bovis_AF2122/97 --------------------------------------------MPTVTW
Rv0232|M.tuberculosis_H37Rv --------------------------------------------MPTVTW
MMAR_0489|M.marinum_M --------------------------------------------MPTVTW
MUL_1152|M.ulcerans_Agy99 --------------------------------------------MPTVTW
Mvan_3467|M.vanbaalenii_PYR-1 --------------------------------------------MPTVTW
MAB_4946|M.abscessus_ATCC_1997 ---------------------------------------MEDPAEPPIRM
Mflv_1535|M.gilvum_PYR-GCK --------------------------------------------MASRRG
MSMEG_2193|M.smegmatis_MC2_155 ----------------------------------------------MARQ
TH_0258|M.thermoresistible__bu -----------------------------------VSRADGGQRRASYQR
MLBr_01733|M.leprae_Br4923 MTRRSIHTRKPLKWSGCAGQHVRSGKVFDVGRISLSYPSMKPGVKIDARS
MAV_5138|M.avium_104 --------------------------------------------MPADSS
Mb0237|M.bovis_AF2122/97 ARVDPARR-----AAVVEAAEAEFGAHGFSRGSLNVIARRAGVAKGSLFQ
Rv0232|M.tuberculosis_H37Rv ARVDPARR-----AAVVEAAEAEFGAHGFSRGSLNVIARRAGVAKGSLFQ
MMAR_0489|M.marinum_M ARVDPARR-----AAIVEAAEAEFGAHGFSQGSLNVIARRARVAKGSLFQ
MUL_1152|M.ulcerans_Agy99 ARVDPARR-----AAIVEAAEAEFGAHGFSQGSLNVIARRARVAKGSLFQ
Mvan_3467|M.vanbaalenii_PYR-1 SRLNEDRR-----AAVVAAAEAEFAAHGFSQGSLNVIARRAGVAKGSLFQ
MAB_4946|M.abscessus_ATCC_1997 ADRQRARRSELVKEEVVEAALAEFSERGYHQTSIAHIAERLGTGHSMFYR
Mflv_1535|M.gilvum_PYR-GCK RPRSEAVR-----SAVLTAAAELALAGGPAAASVEAIARRAEVSRTTIYK
MSMEG_2193|M.smegmatis_MC2_155 ARAGVTRR------KIITAAVDLFAEIGYPATGLGEIIERADMTKGALYY
TH_0258|M.thermoresistible__bu ARSRETKR------ALVQAAMALWRTNGYANTTVADICRAAGVSRALFYF
MLBr_01733|M.leprae_Br4923 ERWREHRKKVR--GEIVDAAFRALDRLGP-EVSVREIAEEAGTAKPKIYR
MAV_5138|M.avium_104 TPNGQTRR-----EELLAVATKLFAARGYHGTRMDDVADVIGLNKATVYH
: :: .* * : : : .:
Mb0237|M.bovis_AF2122/97 YFADKRDLYAFIADIASQR-VRSYMEDLIRELDPNRPFFEFLTDLLDGWV
Rv0232|M.tuberculosis_H37Rv YFADKRDLYAFIADIASQR-VRSYMEDLIRELDPNRPFFEFLTDLLDGWV
MMAR_0489|M.marinum_M YFADKRDLYAYIADIASQR-VRTHIEGLIRELDSSRPFFEFLTDLLDGWV
MUL_1152|M.ulcerans_Agy99 YFADKRDLYAYIADIANQR-VRTHIEGLIRELDSSRPFFEFLTDLLDGWV
Mvan_3467|M.vanbaalenii_PYR-1 YFADKRDLYAHITDVGSQR-VRCYMEDQIRVLDPTRPFFAFLTDLLDVWV
MAB_4946|M.abscessus_ATCC_1997 YFTNKRDILEHVVQHATQRTIETLSHTLPGRITSLNEFHDFSVNLGLAYI
Mflv_1535|M.gilvum_PYR-GCK WWPSAPAIVLEGLLDSVRD-----SITRPPGSTSVEAVVHHVCALNAILV
MSMEG_2193|M.smegmatis_MC2_155 HFDSKEALAEAIIAESGASMLAAFQNITETSSPALENLIHGLFVVCDFTR
TH_0258|M.thermoresistible__bu YFPAKEDILFEVGLLSTQA-----ARRRIRSLLRGDYDVDSVIAAALRSL
MLBr_01733|M.leprae_Br4923 HFTDKSDLFEAIGIRLRDMLWAAIFPAIDLATDSAREIIRRSVDEYVSLV
MAV_5138|M.avium_104 YYASKSLILYDIYQQAAER---TLAAVHDDPSMTAREALYQYTVRLLDQI
: :
Mb0237|M.bovis_AF2122/97 AYFAEHPRERALHAAATLEVDTDARISVRSVLHRHYLDVLRPLVRDAHAR
Rv0232|M.tuberculosis_H37Rv AYFAEHPRERALHAAATLEVDTDARISVRSVLHRHYLDVLRPLVRDAHAR
MMAR_0489|M.marinum_M AYFAEHPRERALHAAATLEVDTDARISVRSVIHRHYLEVLRPLVRDALAR
MUL_1152|M.ulcerans_Agy99 AYFAEHPRERALHAAATLEVDTDARISVRSVIHRHYLEVLRPLVRDALAR
Mvan_3467|M.vanbaalenii_PYR-1 AYFAEHPRERSLHAAASFEVDTDTRVSVRAVIHRHYLEVLRPLVRDARGR
MAB_4946|M.abscessus_ATCC_1997 DLVVADPRLSRLLLQQGAAVDAEMTAQFCGVFDAG-AAVLGGLLRDGIES
Mflv_1535|M.gilvum_PYR-GCK DPTVG-PLLRNVIAAS--ASDPAIQQALCDQWIAPRRAAVAATVRDAVEG
MSMEG_2193|M.smegmatis_MC2_155 TDRVADIGLHLLQTFAGINDTTAR-------VYASWLDAISAQLHRAAAE
TH_0258|M.thermoresistible__bu ERSMARNPRELIVQTILEGYRHEHRILAGEEDPATGADMFGELFTRAQQD
MLBr_01733|M.leprae_Br4923 DKHPNVLRVFIQGRFSAQSEATVRTLDEGREITLTMAEMFNNELREMELN
MAV_5138|M.avium_104 AANPEGAAVYFQEQPYITEWFTKEQVAAVREKETQVYEHVHGLIDRGIAS
. .
Mb0237|M.bovis_AF2122/97 GDLRADSDTGALMSLLLLIFPHLALAPYMRGLDPILGLDEPTPEQPALAV
Rv0232|M.tuberculosis_H37Rv GDLRADSDTGALMSLLLLIFPHLALAPYMRGLDPILGLDEPTPEQPALAV
MMAR_0489|M.marinum_M GDLRADSDTDALLSLLLMIFPHLALAPYMRGLDPILGLDEPTPEQPALAV
MUL_1152|M.ulcerans_Agy99 GDLRADSDTDALLSLLLMIFPHLALAPYMRGLDPILGLDEPTPEQPALAV
Mvan_3467|M.vanbaalenii_PYR-1 GDLRPDADTDALLSLLLMILPHLALAPYVRGMDPVLGLDELSPDQPALVV
MAB_4946|M.abscessus_ATCC_1997 GYVREDIDVEAVADSVVG-IPLGILARYG---------HEPNQDILAARV
Mflv_1535|M.gilvum_PYR-GCK GELRDDVDVEVVVDAVVS----PPYYR----------LVLGMPPLDDRAI
MSMEG_2193|M.smegmatis_MC2_155 GDLREGLDPGAVADVVLSALLGAEALTRAGTSG--TDLRERLVRTWDLLL
TH_0258|M.thermoresistible__bu GKLAAGIDVDHLSRVAQMLVSEGVRHWAAGGFG-----DRSFTEVVAGDI
MLBr_01733|M.leprae_Br4923 RAASELAAFAAFGSVASATEWWLGPEPDSPRRMPREQFVAHLTIIMMAVI
MAV_5138|M.avium_104 GEFYECDSHVLALGYIGMTLGAYRWLRPSGRRSAKEIAAEFSTALLRGLI
:
Mb0237|M.bovis_AF2122/97 RRLVAVLAAAFDAQHPATNSAQTRSEEIT--
Rv0232|M.tuberculosis_H37Rv RRLVAVLAAAFDAQHPATNSAQTRSEEIT--
MMAR_0489|M.marinum_M RRLVAVLTAAYSP----SLTVEVR--KVT--
MUL_1152|M.ulcerans_Agy99 RRLVAVLTAAYSP----SLTVEVR--KVT--
Mvan_3467|M.vanbaalenii_PYR-1 RRYVAVLAAAFAP---QPLTTATPGGAQSHG
MAB_4946|M.abscessus_ATCC_1997 RATADLVCRGIAP------------------
Mflv_1535|M.gilvum_PYR-GCK DGLVRAVWRGYRH------------------
MSMEG_2193|M.smegmatis_MC2_155 PALVEPASLDYFREFLARESMRRSPGTD---
TH_0258|M.thermoresistible__bu AALIDGYNLRLRR------------------
MLBr_01733|M.leprae_Br4923 VGTAETLGISMNPDRPIHDAVPLDRSAS---
MAV_5138|M.avium_104 RDEEIRTTSPLGP------------------