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VTTGSAIRSRKTPTGREEVAAAVLEAAADLFAERGPAATSIRDIAARSKVNHGLVFRHFGAKEQLVGAVL DYLGTHLTELLRAGTPADDLERALDRQMRVWARTLLDGYPAEQLQTRFPNVAELLGQVRVHHGDDTTARL AVANAIALCLGWRLFEPMLRSATGLDELADADLRQAVTDEVARIIEPSGRG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_0905 | - | - | 100% (191) | transcriptional regulator |
| M. ulcerans Agy99 | MUL_3981 | - | 1e-07 | 31.21% (141) | putative regulatory protein |
| M. ulcerans Agy99 | MUL_1500 | - | 3e-07 | 40.00% (65) | transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3439c | - | 1e-69 | 72.19% (187) | transcriptional regulatory protein |
| M. gilvum PYR-GCK | Mflv_1483 | - | 4e-09 | 41.38% (87) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv3405c | - | 1e-69 | 72.19% (187) | transcriptional regulatory protein |
| M. leprae Br4923 | MLBr_00316 | - | 3e-05 | 34.09% (88) | putative TetR/AcrR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_0085c | - | 2e-49 | 54.29% (175) | putative transcriptional regulator |
| M. marinum M | MMAR_1142 | - | 1e-91 | 99.41% (169) | transcriptional regulator |
| M. avium 104 | MAV_4351 | - | 8e-62 | 71.26% (167) | putative HTH-type transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_0180 | - | 2e-39 | 56.38% (149) | putative HTH-type transcriptional regulator |
| M. thermoresistible (build 8) | TH_2070 | - | 3e-08 | 46.55% (58) | PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY |
| M. vanbaalenii PYR-1 | Mvan_4778 | - | 5e-08 | 45.45% (66) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MUL_0905|M.ulcerans_Agy99 -------MTTGSAIRSRKTPTGREEVAAAVLEAAADLFAERGPAATSIRD
MMAR_1142|M.marinum_M -----------------------------MLEAAADLFAERGPAATSIRD
Mb3439c|M.bovis_AF2122/97 -------MTTRPATDRRKMPTGREEVAAAILQAATDLFAERGPAATSIRD
Rv3405c|M.tuberculosis_H37Rv -------MTTRPATDRRKMPTGREEVAAAILQAATDLFAERGPAATSIRD
MAV_4351|M.avium_104 -------------------------MAAAILEAATDLFAERGPAATSIRD
MAB_0085c|M.abscessus_ATCC_199 -------MTTPEATDAK--PVGKEEVVEAVLTAASALFAEKGPAATSIRE
MSMEG_0180|M.smegmatis_MC2_155 -------MTTASGGQRD----AGARIRPVVLTHAADLFAERGPAATSLRD
Mflv_1483|M.gilvum_PYR-GCK --------MDRALPSRR----------DELLQLAATMFADRGLRATTVRD
TH_2070|M.thermoresistible__bu -------MTNSGPPTRR----------DELLELAAQMFAERGLKATTVRD
Mvan_4778|M.vanbaalenii_PYR-1 MAVSDKRGGPDTHVRAPRARMTGTERRQQLVEIAKSLFAERGFDGTSIEE
MLBr_00316|M.leprae_Br4923 MSVPRSGLSVQMAQPARPLRADAARNRARILGVAYEAFATEG-LSVPIDE
:: * ** .* ...: :
MUL_0905|M.ulcerans_Agy99 IAARSKVNHGLVFRHFGAKEQLVGAVLDYLGTHLTE-----LLRAGTPAD
MMAR_1142|M.marinum_M IAARSKVNHGLVFRHFGAKEQLVGAVLDYLGTHLTE-----LLRAGTPAD
Mb3439c|M.bovis_AF2122/97 IAARSKVNHGLVFRHFGTKDQLVGAVLDHLGTKLTR-----LLHSEAPAD
Rv3405c|M.tuberculosis_H37Rv IAARSKVNHGLVFRHFGTKDQLVGAVLDHLGTKLTR-----LLHSEAPAD
MAV_4351|M.avium_104 IAARCGVNHGLVFRHFGTKEQLVGAVLDHLGANLSA-----LLATDTPAE
MAB_0085c|M.abscessus_ATCC_199 VATRAGVNHGLVHRHFGSKRQLLAATLQHLADTAAA-----VREAGAPIE
MSMEG_0180|M.smegmatis_MC2_155 VAERSGVNAGLIFRHIGNKEALVAAVLDFLADELVT-----ARGTDAPEE
Mflv_1483|M.gilvum_PYR-GCK IADSAGILSGSLYHHFKSKEQMVEEVLKDFLDWLFTRYDEIVAATTDPLE
TH_2070|M.thermoresistible__bu IADSAGILSGSLYHHFASKEEMVDEVLRGFLDWLFDRYRSIVETEPNPLE
Mvan_4778|M.vanbaalenii_PYR-1 IALRANVSKPVVYEHFGGKEGLYAVVVDREMSALLDGITSSLADNRSRVR
MLBr_00316|M.leprae_Br4923 IARRAGVGAGTVYRHFPTKEALCAAVIGDRMPHLVDDG-YVLLKSAGPGE
:* . : :..*: * : .:
MUL_0905|M.ulcerans_Agy99 DLERALDRQMRVWAR----TLLDGYPAEQLQT--RFPNVAELLGQVRVHH
MMAR_1142|M.marinum_M DLERALDRQMRVWAR----TLLDGYPAEQLQT--RFPNVAELLGQVRVHH
Mb3439c|M.bovis_AF2122/97 IIERALDRHGRVLAR----ALLDGYPVGQLQQ--RFPNVAELLDAVRPRY
Rv3405c|M.tuberculosis_H37Rv IIERALDRHGRVLAR----ALLDGYPVGQLQQ--RFPNVAELLDAVRPRY
MAV_4351|M.avium_104 VVEQSLDRQMRVMAR----TVLDGYPAGQLQK--RFPNIATLLDGVRPLH
MAB_0085c|M.abscessus_ATCC_199 ELEAAHDLQLRVMVR----STLDGFPIEELQE--RKPGMAWLLEQVRPGH
MSMEG_0180|M.smegmatis_MC2_155 VIEAHVERSWKVIAR----ALLDGYDVGALQH--RFPVVEELVEAARQRH
Mflv_1483|M.gilvum_PYR-GCK RVSGLFMVSFEAIEHRHAQVVIYQDEAKRLNSLPQFGFLDDRNRQQRRMW
TH_2070|M.thermoresistible__bu RFKGLFMASFEAIEHRHAQVVIYQDEAKRLSSQPRFAYVEQRNREQRKMW
Mvan_4778|M.vanbaalenii_PYR-1 VERVALALLTYVEEHTDGFRILIRDSPASITS----GTYSTLLNDAVSQV
MLBr_00316|M.leprae_Br4923 ALFTYLRSLVLHWGA------TDRGLVDALAGAGGIDILG-VAPDAEDAF
:
MUL_0905|M.ulcerans_Agy99 GDDTTARLAV---ANAIALCLGWRLFEPMLRSATGLDELADADLRQAVTD
MMAR_1142|M.marinum_M GDDTTARLAV---ANAIALRLGWRLFEPMLRSATGLDELADADLRQAVTD
Mb3439c|M.bovis_AF2122/97 DSDLGARLAV---AHALALQFGWRLFAPMLRSATGIDELTGDELRLSVND
Rv3405c|M.tuberculosis_H37Rv DSDLGARLAV---AHALALQFGWRLFAPMLRSATGIDELTGDELRLSVND
MAV_4351|M.avium_104 DDELHARLAV---ANALALQFGWRLFAPILRAATGIEELTDAELRRAAGA
MAB_0085c|M.abscessus_ATCC_199 ADERDARLAA---AHAIALQLGWRLMGPSLRAGFGLDDMSDADMRAEIAQ
MSMEG_0180|M.smegmatis_MC2_155 QDDHAARAAT---ADAIALQLGWRLFGPFLRAATGLDDNHPPAD------
Mflv_1483|M.gilvum_PYR-GCK VEVLKQGIAEGSFRPDIDVDLVYRFIRDTTWVSVRWYQPGGPLTAEQVGR
TH_2070|M.thermoresistible__bu VDVLTQGIEEGYFRSDIDVDLVYRFIRDTTWVSVRWYRPGGPLTAEEVGR
Mvan_4778|M.vanbaalenii_PYR-1 ASILAGDFSRRGLDPDLAPLYAQALVGSVSMAAQWWLDVREPKK-EVVAA
MLBr_00316|M.leprae_Br4923 LTILSDLLYAAQYAGTARTDVGVREVKSILVGCQAMEAYN-----SALAE
.
MUL_0905|M.ulcerans_Agy99 EVARII---EPSGRG-------
MMAR_1142|M.marinum_M EVARII---EPSGRG-------
Mb3439c|M.bovis_AF2122/97 AVARIL---EPH----------
Rv3405c|M.tuberculosis_H37Rv AVARIL---EPH----------
MAV_4351|M.avium_104 EVERILRSPDPH----------
MAB_0085c|M.abscessus_ATCC_199 QIAKIV---TPH----------
MSMEG_0180|M.smegmatis_MC2_155 ----------------------
Mflv_1483|M.gilvum_PYR-GCK QYLAIVLGGITEGSK-------
TH_2070|M.thermoresistible__bu QYLSIVLGGITAGAN-------
Mvan_4778|M.vanbaalenii_PYR-1 HLVNLCWNGLTHLESDPVLHEE
MLBr_00316|M.leprae_Br4923 RVTDVVVDGLRAAR--------