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AAAILEAATDLFAERGPAATSIRDIAARCGVNHGLVFRHFGTKEQLVGAVLDHLGANLSALLATDTPAEV VEQSLDRQMRVMARTVLDGYPAGQLQKRFPNIATLLDGVRPLHDDELHARLAVANALALQFGWRLFAPIL RAATGIEELTDAELRRAAGAEVERILRSPDPH*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_4351 | - | - | 100% (173) | putative HTH-type transcriptional regulator |
| M. avium 104 | MAV_0603 | - | 1e-07 | 47.92% (48) | transcriptional regulator, TetR family protein |
| M. avium 104 | MAV_1159 | - | 4e-07 | 41.03% (78) | transcriptional regulator, TetR family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3439c | - | 7e-66 | 71.68% (173) | transcriptional regulatory protein |
| M. gilvum PYR-GCK | Mflv_5008 | - | 7e-10 | 41.77% (79) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv3405c | - | 7e-66 | 71.68% (173) | transcriptional regulatory protein |
| M. leprae Br4923 | MLBr_00316 | - | 1e-05 | 40.54% (74) | putative TetR/AcrR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_0085c | - | 6e-45 | 51.50% (167) | putative transcriptional regulator |
| M. marinum M | MMAR_1142 | - | 2e-60 | 70.55% (163) | transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_0180 | - | 5e-42 | 54.36% (149) | putative HTH-type transcriptional regulator |
| M. thermoresistible (build 8) | TH_4110 | - | 9e-10 | 38.46% (91) | PUTATIVE putative transcriptional regulator, TetR family |
| M. ulcerans Agy99 | MUL_0905 | - | 6e-62 | 71.26% (167) | transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_1492 | - | 1e-09 | 54.24% (59) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3439c|M.bovis_AF2122/97 -------MTTRPATDRRKMPTGREEVAAAILQAATDLFAERGPAATSIRD
Rv3405c|M.tuberculosis_H37Rv -------MTTRPATDRRKMPTGREEVAAAILQAATDLFAERGPAATSIRD
MMAR_1142|M.marinum_M -----------------------------MLEAAADLFAERGPAATSIRD
MUL_0905|M.ulcerans_Agy99 -------MTTGSAIRSRKTPTGREEVAAAVLEAAADLFAERGPAATSIRD
MAV_4351|M.avium_104 -------------------------MAAAILEAATDLFAERGPAATSIRD
MAB_0085c|M.abscessus_ATCC_199 -------MTTPEATDAK--PVGKEEVVEAVLTAASALFAEKGPAATSIRE
MSMEG_0180|M.smegmatis_MC2_155 -------MTTASGGQRD----AGARIRPVVLTHAADLFAERGPAATSLRD
Mflv_5008|M.gilvum_PYR-GCK -----------MTAPVRGRPRDPDADRA-ILQAALDLFIERGVEGSSIEQ
TH_4110|M.thermoresistible__bu --VTATDAAATGRAAARGRPRDPALDSA-ILDAALEIFVEQGISALSIEQ
MLBr_00316|M.leprae_Br4923 MSVPRSGLSVQMAQPARPLRADAARNRARILGVAYEAFATEGLS-VPIDE
Mvan_1492|M.vanbaalenii_PYR-1 -----------MTPPDRPVRADAARNRALLLAAAEEEFAERGPS-ASVAD
:* * * .* .: :
Mb3439c|M.bovis_AF2122/97 IAARSKVNHGLVFRHFGTKDQLVGAVLDHLGTKLT-----RLLHSEAPAD
Rv3405c|M.tuberculosis_H37Rv IAARSKVNHGLVFRHFGTKDQLVGAVLDHLGTKLT-----RLLHSEAPAD
MMAR_1142|M.marinum_M IAARSKVNHGLVFRHFGAKEQLVGAVLDYLGTHLT-----ELLRAGTPAD
MUL_0905|M.ulcerans_Agy99 IAARSKVNHGLVFRHFGAKEQLVGAVLDYLGTHLT-----ELLRAGTPAD
MAV_4351|M.avium_104 IAARCGVNHGLVFRHFGTKEQLVGAVLDHLGANLS-----ALLATDTPAE
MAB_0085c|M.abscessus_ATCC_199 VATRAGVNHGLVHRHFGSKRQLLAATLQHLADTAA-----AVREAGAPIE
MSMEG_0180|M.smegmatis_MC2_155 VAERSGVNAGLIFRHIGNKEALVAAVLDFLADELV-----TARGTDAPEE
Mflv_5008|M.gilvum_PYR-GCK IAKRAGVGKPTVYRRWGTKEELIAAAMETLVAEEVGWTSPEAIETRSPHV
TH_4110|M.thermoresistible__bu VARRAGVGKPTIYRRWSDKEQLVADAIEHRVSAELAWPTPAEASVSDPYE
MLBr_00316|M.leprae_Br4923 IARRAGVGAGTVYRHFPTKEALCAAVIGDRMPHLVDDGY-VLLKSAGPGE
Mvan_1492|M.vanbaalenii_PYR-1 IARRAGVAKGTVFRHFPTKEDLIAAIVSEHIAVLAAAAR-RLADSPDPGA
:* *. * :.*: * * . : *
Mb3439c|M.bovis_AF2122/97 IIERALDRHGRVLARALLDGYPVGQLQQ------RFPNVAELLDAVRPRY
Rv3405c|M.tuberculosis_H37Rv IIERALDRHGRVLARALLDGYPVGQLQQ------RFPNVAELLDAVRPRY
MMAR_1142|M.marinum_M DLERALDRQMRVWARTLLDGYPAEQLQT------RFPNVAELLGQVRVHH
MUL_0905|M.ulcerans_Agy99 DLERALDRQMRVWARTLLDGYPAEQLQT------RFPNVAELLGQVRVHH
MAV_4351|M.avium_104 VVEQSLDRQMRVMARTVLDGYPAGQLQK------RFPNIATLLDGVRPLH
MAB_0085c|M.abscessus_ATCC_199 ELEAAHDLQLRVMVRSTLDGFPIEELQE------RKPGMAWLLEQVRPGH
MSMEG_0180|M.smegmatis_MC2_155 VIEAHVERSWKVIARALLDGYDVGALQH------RFPVVEELVEAARQRH
Mflv_5008|M.gilvum_PYR-GCK LVEAAIDSAAAATAAPYYRALVARVYGSAVSHPELMTVYWDRYILPRRVQ
TH_4110|M.thermoresistible__bu LVRRNISAAARTAADPAFRGLIAAIYGSAVTHPALLRTYWEHYILPRRTA
MLBr_00316|M.leprae_Br4923 ALFTYLRSLVLHWGATDRGLVDALAGAGGIDILGVAPDAEDAFLT----I
Mvan_1492|M.vanbaalenii_PYR-1 ALLEFLTIAADQRQRHDLTFLQSASDGD-----PRVTEVRDALHA----N
:
Mb3439c|M.bovis_AF2122/97 DSDLGARLAVAHALALQFGWRLFAPMLRSATGIDELTGDELRLSVNDAVA
Rv3405c|M.tuberculosis_H37Rv DSDLGARLAVAHALALQFGWRLFAPMLRSATGIDELTGDELRLSVNDAVA
MMAR_1142|M.marinum_M GDDTTARLAVANAIALRLGWRLFEPMLRSATGLDELADADLRQAVTDEVA
MUL_0905|M.ulcerans_Agy99 GDDTTARLAVANAIALCLGWRLFEPMLRSATGLDELADADLRQAVTDEVA
MAV_4351|M.avium_104 DDELHARLAVANALALQFGWRLFAPILRAATGIEELTDAELRRAAGAEVE
MAB_0085c|M.abscessus_ATCC_199 ADERDARLAAAHAIALQLGWRLMGPSLRAGFGLDDMSDADMRAEIAQQIA
MSMEG_0180|M.smegmatis_MC2_155 QDDHAARAATADAIALQLGWRLFGPFLRAATGLDDNHPPAD---------
Mflv_5008|M.gilvum_PYR-GCK ATRLLERARELGTVAADTDLDVAIDMMVG--AITYRVLRPNPPDVDEMRR
TH_4110|M.thermoresistible__bu AIALLRRARDLGTVAADADLDVLVDMLAG--AVTYRVLQPEPPSARQLRC
MLBr_00316|M.leprae_Br4923 LSDLLYAAQYAGTARTDVGVREVKSILVG----CQAMEAYNSALAERVTD
Mvan_1492|M.vanbaalenii_PYR-1 LETLVDRARTSGAIRADITEADVFLMMCAPIHIVENLPAPAPLLWQRYLA
: : .
Mb3439c|M.bovis_AF2122/97 RILEPH----------------
Rv3405c|M.tuberculosis_H37Rv RILEPH----------------
MMAR_1142|M.marinum_M RIIEPSGRG-------------
MUL_0905|M.ulcerans_Agy99 RIIEPSGRG-------------
MAV_4351|M.avium_104 RILRSPDPH-------------
MAB_0085c|M.abscessus_ATCC_199 KIVTPH----------------
MSMEG_0180|M.smegmatis_MC2_155 ----------------------
Mflv_5008|M.gilvum_PYR-GCK YLREVYRQAGLLPPG-------
TH_4110|M.thermoresistible__bu YLEVAYRQVGLLP---------
MLBr_00316|M.leprae_Br4923 VVVDGLRAAR------------
Mvan_1492|M.vanbaalenii_PYR-1 IIFDGLRPDGAHPLPQPAPAAP