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aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_4641 | - | - | 100% (503) | oxygenase |
| M. thermoresistible (build 8) | TH_1880 | - | 4e-50 | 34.00% (497) | flavin-type hydroxylase |
| M. thermoresistible (build 8) | TH_0968 | - | 4e-29 | 29.51% (410) | 3-(3-hydroxy-phenyl)propionate hydroxylase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1780 | - | 8e-12 | 25.51% (392) | hypothetical protein Mb1780 |
| M. gilvum PYR-GCK | Mflv_5009 | - | 1e-160 | 58.74% (509) | monooxygenase, FAD-binding |
| M. tuberculosis H37Rv | Rv1751 | - | 4e-11 | 25.26% (392) | hypothetical protein Rv1751 |
| M. leprae Br4923 | MLBr_02276 | - | 6e-09 | 25.07% (335) | putative FAD-linked oxidoreductase |
| M. abscessus ATCC 19977 | MAB_0857 | - | 3e-56 | 36.47% (510) | hypothetical protein MAB_0857 |
| M. marinum M | MMAR_4271 | - | 5e-50 | 33.87% (499) | hypothetical protein MMAR_4271 |
| M. avium 104 | MAV_2736 | - | 3e-51 | 34.49% (490) | hypothetical protein MAV_2736 |
| M. smegmatis MC2 155 | MSMEG_1499 | - | 1e-163 | 59.22% (510) | oxygenase |
| M. ulcerans Agy99 | MUL_3663 | - | 2e-10 | 28.65% (342) | hypothetical protein MUL_3663 |
| M. vanbaalenii PYR-1 | Mvan_0779 | - | 1e-162 | 59.02% (510) | monooxygenase, FAD-binding |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_5009|M.gilvum_PYR-GCK ----------------------------------------------MPGA
MSMEG_1499|M.smegmatis_MC2_155 -----------------------------------------------MAA
Mvan_0779|M.vanbaalenii_PYR-1 -------------------------------------------------M
TH_4641|M.thermoresistible__bu ----------------------------------------------MARE
MMAR_4271|M.marinum_M -------------------------------------------------M
MAV_2736|M.avium_104 ---------------------------------------MRGVRFSERSV
MAB_0857|M.abscessus_ATCC_1997 -------------------------------------------------M
Mb1780|M.bovis_AF2122/97 MIATMPSMARRSRHDNKITTPAVDCLTIERLDSPASGAPQVTPYARALMG
Rv1751|M.tuberculosis_H37Rv MIATMPSMARRSRHDNKITTPAVDCLTIERLDSPASGAPQVTPYARALMG
MUL_3663|M.ulcerans_Agy99 -------------------------------------MPQPS--------
MLBr_02276|M.leprae_Br4923 ----------------------------------------------MRVE
Mflv_5009|M.gilvum_PYR-GCK HRSDVVVVGAGPTGLTLACCLRLHGVSVRVLDAAAGPATT-SRANFLHAR
MSMEG_1499|M.smegmatis_MC2_155 TDCDVIVVGAGPTGLTLACSLRLHGLSVRVLDRAAGPATT-SRANFLHAR
Mvan_0779|M.vanbaalenii_PYR-1 TDTDVVVVGAGPTGLTLACALRLHGLTVQVVDRAAGPATT-SRANFLHAR
TH_4641|M.thermoresistible__bu TTTDVVVVGAGPVGLAVACGLLAHGLDVRVIDKAPAPATT-SRANFLHAR
MMAR_4271|M.marinum_M ADHAVVVVGAGPTGLMLAGELALAGVDVAVVERRVSQDLVGSRAGGLHSR
MAV_2736|M.avium_104 RGHAVLVAGAGPTGLMLAGELGLAGVDVALVERRADQQLIGSRAGGLHAR
MAB_0857|M.abscessus_ATCC_1997 AEHAVVVAGAGPTGLMLAGELALAGIDVALLERRGSHEEVGSRAAGLHSR
Mb1780|M.bovis_AF2122/97 ETTTCAIIGGGPAGMVLGLLLARAGVQVTLLEKHGDFLRD-FRGDTVHPT
Rv1751|M.tuberculosis_H37Rv ETTTCAIIGGGPAGMVLGLLLARAGVQVTLLEKHGDFLRD-FRGDTVHPT
MUL_3663|M.ulcerans_Agy99 ETTSVLVAGGGPAGMVLGLLLARAGVDVTVMEKHADFLRD-SRGDTVHAS
MLBr_02276|M.leprae_Br4923 TSADVVVVGAGPAGSAAATWAARAGNDVIVIDSVCFPRDK-ACGDGLTPR
: *.**.* . * * ::: . : .
Mflv_5009|M.gilvum_PYR-GCK GSEVLDRMGALGTLPQESLRAL-RITNYLGDRPLATLEFGDPGMRTAAPP
MSMEG_1499|M.smegmatis_MC2_155 GSEVLNRIGALGTLPDESLRAM-RITNYLGDRPVMTLTFGDPGMRTAAPP
Mvan_0779|M.vanbaalenii_PYR-1 GSEVLGRIGALGTLPDESLRAM-RITNYLGDRPLVTLEFGDPRMRTAAPP
TH_4641|M.thermoresistible__bu GSEVLDRLGALGGLPERSVRAM-QITTHLGGEPVMRMQFGDPGMRTAAPP
MMAR_4271|M.marinum_M TIEVLDQRGIADRFLAQGT------ATQVARFAAIPLDISDFPTRHNYG-
MAV_2736|M.avium_104 TLEILDQRGIVDRFLAEGQ------VAQVAGFAQIRLDISDFPTRHPYG-
MAB_0857|M.abscessus_ATCC_1997 TIEVFDQRGIAERFLAQGR------TGQVTHFSGIFMSIEDFPTRHPYA-
Mb1780|M.bovis_AF2122/97 TMRLLDELGLWERFAALPYSEVRTATLHSNGRAVTYIDFERLHQPYPYVA
Rv1751|M.tuberculosis_H37Rv TMRLLDELGLWERFAALPYSEVRTATLHSNGRAVTYIDFERLHQPYPYVA
MUL_3663|M.ulcerans_Agy99 TLRLLDELGLGSQFAQIPHRLIDTISMKVQGQPVD-LDLKHLPGAHQHIA
MLBr_02276|M.leprae_Br4923 AVAELKRLGLDDWLNTRIRHRGLRMSGFGG-----EVEVDWPGPSFPSTS
: . * : : .
Mflv_5009|M.gilvum_PYR-GCK MVVSQAKVEAALRARLADLDVEPEWGRKVIDVRE-------DADGVVADL
MSMEG_1499|M.smegmatis_MC2_155 MVVSQARVEAALRARLAQLGVEPEWGRKVAGVRQ-------AGDRVVADL
Mvan_0779|M.vanbaalenii_PYR-1 MVISQAKVEASLRSRLADLGAEPQWGNGLAALHR-------NDDTVVAEL
TH_4641|M.thermoresistible__bu MVISQAEVEAALRNRLAELGGRVELDCPLTGLRQ-------DASTVTAGI
MMAR_4271|M.marinum_M LALWQNRIERILAEWVAELRVRIYRGCEVTDITQ-------DDNGVDLTL
MAV_2736|M.avium_104 LALWQNHIERILADWVGELGVPIYRGHRIATCTQ-------DDTGVDVVA
MAB_0857|M.abscessus_ATCC_1997 LGLLQHYTEKTLAAWIDELGVPIYYNAEAVGLGQ-------DDVGVDVAL
Mb1780|M.bovis_AF2122/97 MVPQWDLLNLLAEAAQAEPSFTLRMKTEVTGLLR----EGGKVTGVRYQG
Rv1751|M.tuberculosis_H37Rv MVPQWDLLNLLAEAAQAEPSFTLRMKTEVTGLLR----EGGKVTGVRYQG
MUL_3663|M.ulcerans_Agy99 LVPQWDFLELLAAAAEAEPTFRLLRSTEVTGVLWGDGPDPGRVVSATYRA
MLBr_02276|M.leprae_Br4923 SAVPRLELDDRIRKVAENSGARMLLGTKAVSVYHD-----SSRRAASVTL
: : .
Mflv_5009|M.gilvum_PYR-GCK ADG--ARVRGQWLVGCDGTTSVVRRQTGIEFPGVRLSERFLLADIHLDWA
MSMEG_1499|M.smegmatis_MC2_155 ADG--AQVSGQWLVGCDGTSSATREQVGIPFPGVKLSERFLLADIHLDWA
Mvan_0779|M.vanbaalenii_PYR-1 DDG--TSVEARWLVGCDGTASTTRKLAGIGFPGVKLTERWLLADLHLDWD
TH_4641|M.thermoresistible__bu GGG--GELRGRWLVGCDGTGSSTRKSVGIGYPGARLSERFLLADVYLDWR
MMAR_4271|M.marinum_M SDG--PPLRADYVVGCDGGRSLVRRAVGIDFPGWDPTTSSLIAEVEVAVG
MAV_2736|M.avium_104 SDG--RTLRGQYLVGCDGGRSVIRKAAGIDFPGWEATTSYLLAEAEMDWR
MAB_0857|M.abscessus_ATCC_1997 ADG--STLRGQYLVGCDGGRSTIRKAAGIGFPGHDPSCSAMLVDAEI---
Mb1780|M.bovis_AF2122/97 AEG-PGELRAELTVACDGRWSIARHEAGLKAR--EFPVNFDVWWFKLPRE
Rv1751|M.tuberculosis_H37Rv AEG-PGELRAELTVACDGRWSIARHEAGLKAR--EFPVNFDVWWFKLPRE
MUL_3663|M.ulcerans_Agy99 QSGETKHMHADLTVACDGRGSTVRSALGMATR--SFGAPMDVWWFRLPRR
MLBr_02276|M.leprae_Br4923 ADG--TEVGCRQLIIADGARSPLGRKLGRSWHQKTVYGVAARGYLTTPRS
* : : .** * *
Mflv_5009|M.gilvum_PYR-GCK VDRAG--TTGWIHPDGVVGAMPMPSTDGRDDLWRLFVYDPSLDRKPTDSE
MSMEG_1499|M.smegmatis_MC2_155 VDRGG--TTGWIHPDGVVGAMPMPSGDGRNDLWRLFVYDPALNRKPSDSE
Mvan_0779|M.vanbaalenii_PYR-1 LDRGG--TTGWIHPGGLLGAMPMPDSSGAHDLWRVFAYDPGHTEKPAESE
TH_4641|M.thermoresistible__bu LDRSG--TTGWIHPDGMVGAMPMPDG-----LWRIIAYDPGPGDLDQG--
MMAR_4271|M.marinum_M SESGP--NLGEVRHDALGVHGFTRLPDGGPLRVVVTERQLDAGGEPSLGD
MAV_2736|M.avium_104 TGQPP--QWG-IHHDSLGVHALSETEPAGGVRVLVTERQLRSAAEPNLDD
MAB_0857|M.abscessus_ATCC_1997 TEQPL--EFGLLRKPGQAFLGILPFEEG-WCRLAFSTGLDRLGVEPTLEE
Mb1780|M.bovis_AF2122/97 GDAEF--SFLPRFSPG-KGLGVIPREGYFQIAYLGPKGTDAQLRERGIEE
Rv1751|M.tuberculosis_H37Rv GDAEF--SFLPRFSPG-KGLGVIPREGYFQIAYLGPKGTDAQLRERGIEE
MUL_3663|M.ulcerans_Agy99 PDDPT--GLAGIFNSG-HGGIAIDRGDYYQIAYIIPKGSDAQLRAQGIEA
MLBr_02276|M.leprae_Br4923 DDLWLTSHLELRSPDGAVLPGYGWIFPLGNGEVNIGVGALSTSKRPADLA
.
Mflv_5009|M.gilvum_PYR-GCK ILDRISELVPYRTGRRVKIGDAEWLSMFTVHRRLADTYRRG-RVLIAGDA
MSMEG_1499|M.smegmatis_MC2_155 ILQRIEQIVPYRTGRAITIGQPEWLSMFTVHRRLAQSYRRG-RVLIAGDA
Mvan_0779|M.vanbaalenii_PYR-1 ILERMRQVIPQRSGRRVHVGDPEWLSVFTVHRRLADRYRQG-RILIAGDA
TH_4641|M.thermoresistible__bu ---ALERLLYERTGHRVKVTGTVWQSEFRVHRRLADTYRRG-RVFIAGDA
MMAR_4271|M.marinum_M LSAALTAVYGTDYG----IHSPTWISRFTDLTRQAATYRQG-RVLIAGDA
MAV_2736|M.avium_104 LRQALIAVYRTDYG----IHSPRWISRFTDAARQAARYRDR-RVLLAGDA
MAB_0857|M.abscessus_ATCC_1997 AKEALIAIAGTDFG----IHNPRWISRFSDMTRQADRYRDG-RVFLAGDS
Mb1780|M.bovis_AF2122/97 FRRDVSELLPEATASVAALASTDEVKHLNVKVNRLRRWHID-GLLCIGDA
Rv1751|M.tuberculosis_H37Rv FRRDVSELLPEATASVAALASMDEVKHLNVKVNRLRRWHID-GLLCIGDA
MUL_3663|M.ulcerans_Agy99 LHRALADLMPWLADRVDALKSFDDVKLLDVQLNRLRRWYCD-GALCIGDA
MLBr_02276|M.leprae_Br4923 LRSLISYYTDLRRHEWGFSGQPRAVSSALLPMGGAVSGVAGPNWMLIGDA
: . : **:
Mflv_5009|M.gilvum_PYR-GCK AHVHAPFGGQGMLTGIGDAENVGFKLALVVRGLAADDLLDTYEAERRPLA
MSMEG_1499|M.smegmatis_MC2_155 AHAHAPFGGQGMLTGIGDAENLAFKLALVIRGLAADALIDTYEAERRFLA
Mvan_0779|M.vanbaalenii_PYR-1 AHAHAPFGGQGMLTGIGDAENLAFKLALVTRGLAADPFVDTYEAERRPLA
TH_4641|M.thermoresistible__bu AHAHAPFGGQGMLTGLGDAENLAFKLALVIRGYAGPALLDTYEAERRPLA
MMAR_4271|M.marinum_M AHVHDPVGGQGLNTGVQDAVNLGWKLAQVVNRRSPESLLDTYHAERHPVA
MAV_2736|M.avium_104 AHIHHPVGGQGLNTGVQDAVNLGWKLALVVGGASPPALLDTYHAERHPVG
MAB_0857|M.abscessus_ATCC_1997 AHIHFPFGGQGLNTGIQDAVNLGWKLAAVIKGHAPDALLDTYHLERHPVA
Mb1780|M.bovis_AF2122/97 AHAMSPVAGVGINLAVQDAVAAATILAEPLREHRVSSRHLAAVRRRRAFP
Rv1751|M.tuberculosis_H37Rv AHAMSPVAGVGINLAVQDAVAAATILAEPLREHRVSSRHLAAVRRRRAFP
MUL_3663|M.ulcerans_Agy99 AHAMSPVGGVGINLALADAVATARMLAPSLRVGRVSTGQLARVQARRWAP
MLBr_02276|M.leprae_Br4923 AACVNPLNGEGIDYGLETGRLAAELLDLRDLSYVWPSLLQQHYGRGFSVA
* *. * *: .: . . *
Mflv_5009|M.gilvum_PYR-GCK TQVLRGTSAITRVNVAGNPIVRFLRDRVAPRVFGLPAVQRWTTYTASQLW
MSMEG_1499|M.smegmatis_MC2_155 TEVLRGTSAITRVNVASNPVGRFLRDRVATRIFGLPVVQRWTTYTASQLW
Mvan_0779|M.vanbaalenii_PYR-1 TEVLRGTSAVTRVNIAGNPVGRFLRDRVAPKVFGLAPVQRWTTYTASQLW
TH_4641|M.thermoresistible__bu TEVLRNTSAATKLNIADRGVGRFLRDRVVLPLLALPSVQRRLTYQTSQLW
MMAR_4271|M.marinum_M ARVLRTTMAQVALRRLDYRKKALS--DTISELLMMDEPRKRFAAMMSGLD
MAV_2736|M.avium_104 ERVLRNAIAQMALLRPDERTRALR--DLVTELLGMDEPRKRFAAMISGLD
MAB_0857|M.abscessus_ATCC_1997 ERVLHNTMAQTPLSEAGPRIDALR--DIVADLLAMDEPRKRIAGMMSGLD
Mb1780|M.bovis_AF2122/97 TAVTQAVQRVLHRRLLGPLLQGRD-PTPPAALLGLVERLPWLSAVPAYFV
Rv1751|M.tuberculosis_H37Rv TAVTQAVQRVLHRRLLGPLLQGRD-PTPPAALLGLVERLPWLSAVPAYFV
MUL_3663|M.ulcerans_Agy99 TAFLQGIQRAIHAAIVAVAVTGGP-PQPPPVVR-LVSRSVPVRRIMGYLV
MLBr_02276|M.leprae_Br4923 RRLALLLTFKRCLPAIG------------PSAMRSTSLITIAVRVMANLV
. . :
Mflv_5009|M.gilvum_PYR-GCK VSYRNGPLGGRGS---KPRPGDRIDDAPCSRPDGTATRLHGELGGRWALL
MSMEG_1499|M.smegmatis_MC2_155 VSYRKGPLGGHGR---RPRLGDRIGDRPCTRADGAATRLHSELAGRWALL
Mvan_0779|M.vanbaalenii_PYR-1 VSYRKGPLGGRGP---KPRAGDRIPDVACVRPDGTPSLLHRELSGRWALL
TH_4641|M.thermoresistible__bu VTYRGGPLAPRTVSMTTPRPGDRVPDQRCVRDDGHISRLYEQLGGRWAVL
MMAR_4271|M.marinum_M IRYHLGGG--------HPLLGRRMPDLDLTTADGPRRVFTHLHAARPVLL
MAV_2736|M.avium_104 VRYDLGPG--------HPLLGRRMPDLDLVTADGASRVFALLRNARPVLL
MAB_0857|M.abscessus_ATCC_1997 IHYMLGDG--------HQLLGRRMPDLDVVTADGAVRVYEHLHTARPVLF
Mb1780|M.bovis_AF2122/97 G------------------VGVRPEHAPAFARRGPGNRKGP---------
Rv1751|M.tuberculosis_H37Rv G------------------VGVRPEHAPAFARRGPGNRKGP---------
MUL_3663|M.ulcerans_Agy99 A------------------IGPLPEHAPKYPRRAR---------------
MLBr_02276|M.leprae_Br4923 T----------------------DDDADWVARVWRSGGWASWLVDRRPPF
.
Mflv_5009|M.gilvum_PYR-GCK LPRG-----VPAVGAAAVRGPAGYLADHVVTLH---HDRDDVMLVRPDAH
MSMEG_1499|M.smegmatis_MC2_155 WPRD-----APAPGASLLAR----LGDFGVTLR---HDGAEAMLIRPDAH
Mvan_0779|M.vanbaalenii_PYR-1 APPD-----APAGCADVARR---HLGDFVEPLT---FDGDEAMLIRPDGH
TH_4641|M.thermoresistible__bu EPGSGR---HHREGPGLLGTAHTFLGEYVVGLRGAEMRGCDAFLVRPDGH
MMAR_4271|M.marinum_M NLAEPGRFDIAGWRHRVLLIDAKYVGVWELPVLG-AIAAPAAALIRPDGY
MAV_2736|M.avium_104 NFAGAGRRSVAGWADRVRVVDAKCVADWELPVLG-RVSAPPAVLIRPDGH
MAB_0857|M.abscessus_ATCC_1997 NFGARQILNVEGWEDRVHVVDAKYSGIWELPVLG-EVSAPDAVLVRPDGY
Mb1780|M.bovis_AF2122/97 --------------------------------------------------
Rv1751|M.tuberculosis_H37Rv --------------------------------------------------
MUL_3663|M.ulcerans_Agy99 --------------------------------------------------
MLBr_02276|M.leprae_Br4923 S-------------------------------------------------
Mflv_5009|M.gilvum_PYR-GCK LAWRGAHDDPTGLDRWLATALHPGGTQ---------
MSMEG_1499|M.smegmatis_MC2_155 LAWRGAPDDTAGLDHWLAKALGSGAVR---------
Mvan_0779|M.vanbaalenii_PYR-1 LAWRGDAGDADGVNLWLTRALTTGNAR---------
TH_4641|M.thermoresistible__bu LAWRGR--DATDLADWLKSALTVGRVR---------
MMAR_4271|M.marinum_M VAWVGDDLTDRGLFDALTAWFGRPAVPSPRLRASAP
MAV_2736|M.avium_104 VAWAGD-PNDPGLHDALTTWCGPPAAGG--------
MAB_0857|M.abscessus_ATCC_1997 VAWVGE-GSADGLRGALTRWVGSPSRA---------
Mb1780|M.bovis_AF2122/97 ------------------------------------
Rv1751|M.tuberculosis_H37Rv ------------------------------------
MUL_3663|M.ulcerans_Agy99 ------------------------------------
MLBr_02276|M.leprae_Br4923 ------------------------------------