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aa seq not available
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. thermoresistible (build 8) | TH_1880 | - | - | 100% (477) | flavin-type hydroxylase |
M. thermoresistible (build 8) | TH_4641 | - | 4e-50 | 34.00% (497) | PUTATIVE oxygenase |
M. thermoresistible (build 8) | TH_0968 | - | 8e-40 | 32.29% (511) | 3-(3-hydroxy-phenyl)propionate hydroxylase |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb1780 | - | 4e-13 | 26.28% (312) | hypothetical protein Mb1780 |
M. gilvum PYR-GCK | Mflv_5009 | - | 3e-50 | 34.99% (503) | monooxygenase, FAD-binding |
M. tuberculosis H37Rv | Rv1751 | - | 2e-12 | 25.96% (312) | hypothetical protein Rv1751 |
M. leprae Br4923 | MLBr_02276 | - | 2e-05 | 24.68% (312) | putative FAD-linked oxidoreductase |
M. abscessus ATCC 19977 | MAB_0857 | - | 1e-109 | 46.14% (492) | hypothetical protein MAB_0857 |
M. marinum M | MMAR_4271 | - | 1e-103 | 45.33% (492) | hypothetical protein MMAR_4271 |
M. avium 104 | MAV_2736 | - | 1e-106 | 46.86% (493) | hypothetical protein MAV_2736 |
M. smegmatis MC2 155 | MSMEG_2252 | - | 0.0 | 70.50% (478) | flavin-type hydroxylase |
M. ulcerans Agy99 | MUL_0979 | - | 1e-12 | 29.38% (354) | oxidoreductase |
M. vanbaalenii PYR-1 | Mvan_2422 | - | 1e-100 | 44.49% (490) | hypothetical protein Mvan_2422 |
CLUSTAL 2.0.9 multiple sequence alignment Mb1780|M.bovis_AF2122/97 --------------------------------------MIATMPSMARRS Rv1751|M.tuberculosis_H37Rv --------------------------------------MIATMPSMARRS TH_1880|M.thermoresistible__bu ------------------------------------VYDVIVVGGGPTGM MSMEG_2252|M.smegmatis_MC2_155 MADAESLAAHGSRVAG----------------KGISVKDVVIVGGGPTGA MAV_2736|M.avium_104 MRGVRFSE--RSVRG----------------------HAVLVAGAGPTGL Mvan_2422|M.vanbaalenii_PYR-1 MTTTRHKDTHKDTREDTREDTRDDSRDDGGDPNGDTDHAVVVGGGGPTGM MMAR_4271|M.marinum_M MAD----------------------------------HAVVVVGAGPTGL MAB_0857|M.abscessus_ATCC_1997 MAE----------------------------------HAVVVAGAGPTGL Mflv_5009|M.gilvum_PYR-GCK MPGAHR-------------------------------SDVVVVGAGPTGL MUL_0979|M.ulcerans_Agy99 --------------------------------MTTYDTDVLVVGGGPGGL MLBr_02276|M.leprae_Br4923 -------------------------------MRVETSADVVVVGAGPAGS : . . Mb1780|M.bovis_AF2122/97 RHDNKITTPAVDCLTIERLDSPASGAPQVTPYARALMGETTTCAIIG--- Rv1751|M.tuberculosis_H37Rv RHDNKITTPAVDCLTIERLDSPASGAPQVTPYARALMGETTTCAIIG--- TH_1880|M.thermoresistible__bu MLAGELRLHGVRVLVVEKNSEPPAH-VRSLGLHVRSIEMLDQRGLLDRF- MSMEG_2252|M.smegmatis_MC2_155 MLAGELRLYEVDVMVLDKDIEPTKV-VRSLGLHARSIEIMDQRGLLDRF- MAV_2736|M.avium_104 MLAGELGLAGVDVALVERRADQQLIGSRAGGLHARTLEILDQRGIVDRF- Mvan_2422|M.vanbaalenii_PYR-1 MTAAELALAGVDVAVVERRTTPEITGSRAGGLLSRTLEILDQRGVVDRF- MMAR_4271|M.marinum_M MLAGELALAGVDVAVVERRVSQDLVGSRAGGLHSRTIEVLDQRGIADRF- MAB_0857|M.abscessus_ATCC_1997 MLAGELALAGIDVALLERRGSHEEVGSRAAGLHSRTIEVFDQRGIAERF- Mflv_5009|M.gilvum_PYR-GCK TLACCLRLHGVSVRVLDAAAG-PATTSRANFLHARGSEVLDRMGALGTL- MUL_0979|M.ulcerans_Agy99 ATALNARKRGLSVIVADPRESPIDKACGEGLMPGGLAELKS--------- MLBr_02276|M.leprae_Br4923 AAATWAARAGNDVIVIDSVCFPRDKACGDG-LTPRAVAELKRLGLDDWLN : Mb1780|M.bovis_AF2122/97 --GGPAGMVLGLLLARAGVQVTLLEKHGDFLRDFRGDTVHPTTMRLLDEL Rv1751|M.tuberculosis_H37Rv --GGPAGMVLGLLLARAGVQVTLLEKHGDFLRDFRGDTVHPTTMRLLDEL TH_1880|M.thermoresistible__bu LAHGQRHPVGGFFAAIAK-PPAELD----TAHGYVLGIRQPVTDRLLAEW MSMEG_2252|M.smegmatis_MC2_155 LEVGRRHPVGGYFAGITKAPPRTLD----TAHPYVLGIPQPVTDRILVEH MAV_2736|M.avium_104 LAEGQVAQVAG-FAQIRL-DISDFP----TRHPYGLALWQNHIERILADW Mvan_2422|M.vanbaalenii_PYR-1 LSAGETMQVHG-FAQVRL-DVSDLP----TRHPYGLALWQKHIERILAEW MMAR_4271|M.marinum_M LAQGTATQVAR-FAAIPL-DISDFP----TRHNYGLALWQNRIERILAEW MAB_0857|M.abscessus_ATCC_1997 LAQGRTGQVTH-FSGIFM-SIEDFP----TRHPYALGLLQHYTEKTLAAW Mflv_5009|M.gilvum_PYR-GCK PQESLRALRITNYLGDRPLATLEFGDPGMRTAAPPMVVSQAKVEAALRAR MUL_0979|M.ulcerans_Agy99 LDVDPAGVPFQGIAYVSQQRRAEAR----FRTGPGRGVRRTTVHATLAAR MLBr_02276|M.leprae_Br4923 TRIRHRGLRMSGFGGEVEVDWPGPS-----FPSTSSAVPRLELDDRIRKV : : Mb1780|M.bovis_AF2122/97 GLWERFAALPYSEVRTATLHSN--GRAVTYIDFERLHQPYPYVAMVPQWD Rv1751|M.tuberculosis_H37Rv GLWERFAALPYSEVRTATLHSN--GRAVTYIDFERLHQPYPYVAMVPQWD TH_1880|M.thermoresistible__bu AAERGAVIRRGCAVVGLDQDAA--GITVELADGSVQRARYLVGCDGGRST MSMEG_2252|M.smegmatis_MC2_155 AVASGAVLRRGCEAVGLAQDDD--GVSVTLADGTQVRARYVVGCDGGRST MAV_2736|M.avium_104 VGELGVPIYRGHRIATCTQDDT--GVDVVASDGRTLRGQYLVGCDGGRSV Mvan_2422|M.vanbaalenii_PYR-1 VDELAVPVYRGREVVGVRQDGA--GVDIELSDGRVLRAGYLVGCDGGRSL MMAR_4271|M.marinum_M VAELRVRIYRGCEVTDITQDDN--GVDLTLSDGPPLRADYVVGCDGGRSL MAB_0857|M.abscessus_ATCC_1997 IDELGVPIYYNAEAVGLGQDDV--GVDVALADGSTLRGQYLVGCDGGRST Mflv_5009|M.gilvum_PYR-GCK LADLDVEPEWGRKVIDVREDAD--GVVADLADGARVRGQWLVGCDGTTSV MUL_0979|M.ulcerans_Agy99 AKEQDAEWIR-TRVTDVVQDAH--GVTAAG-----VRAKWLVAADGLHSA MLBr_02276|M.leprae_Br4923 AENSGARMLLGTKAVSVYHDSSRRAASVTLADGTEVGCRQLIIADGARSP . . . Mb1780|M.bovis_AF2122/97 LLNLLAEAAQAEPSFTLRMKTEVTGLLREGGKVTGVRYQGAEGPGELRAE Rv1751|M.tuberculosis_H37Rv LLNLLAEAAQAEPSFTLRMKTEVTGLLREGGKVTGVRYQGAEGPGELRAE TH_1880|M.thermoresistible__bu VRKLAGIGFPGEPARSETLLGEMSLSADPATVAAVVAEVRKTQLRFGAMP MSMEG_2252|M.smegmatis_MC2_155 VRKLMGVGFPGEPSRVDTLIGEMQVGVTPEQVTAVVAEVRKMQLRFGAGP MAV_2736|M.avium_104 IRKAAGIDFPGWEATTSYLLAEAEMDWRTGQPPQWG-IHHDSLGVHALSE Mvan_2422|M.vanbaalenii_PYR-1 IRKSAGIEFPGWEPTTSYLLAEVEIAPEDGREPEWG-IRRDALGVHALSR MMAR_4271|M.marinum_M VRRAVGIDFPGWDPTTSSLIAEVEVAVGSESGPNLGEVRHDALGVHGFTR MAB_0857|M.abscessus_ATCC_1997 IRKAAGIGFPGHDPSCSAMLVDAEIT---EQPLEFGLLRKPGQAFLGILP Mflv_5009|M.gilvum_PYR-GCK VRRQTGIEFPGVRLSERFLLADIHLDWAVDRAGTTGWIHPDGVVGAMPMP MUL_0979|M.ulcerans_Agy99 VRRAVGITATAGTPRRYGVRRHYRVP----AWSEFVEVHWSPWGEAYVTP MLBr_02276|M.leprae_Br4923 LGRKLGRSWHQKTVYGVAARGYLTTPRSDDLWLTSHLELRSPDGAVLPGY : . . Mb1780|M.bovis_AF2122/97 LTVACDGRWSIARHEAGLKARE--FPVNFDVWWFKLPREGDAEF------ Rv1751|M.tuberculosis_H37Rv LTVACDGRWSIARHEAGLKARE--FPVNFDVWWFKLPREGDAEF------ TH_1880|M.thermoresistible__bu LG---DGVYRVIVPAEGVAGDR--AEPTLDEFRRRLKAFAGTDFGA--HT MSMEG_2252|M.smegmatis_MC2_155 LG---DGLYRVMVPAAEVVEDRS-ATPTLDEFRQQLRATAGTDLGV--HS MAV_2736|M.avium_104 TEP--AGGVRVLVTERQLRSAA---EPNLDDLRQALIAVYRTDYGI--HS Mvan_2422|M.vanbaalenii_PYR-1 SD---DGPVRIMVTEQDLRRSG---VPDLAELREALVTVYGTDFGI--HS MMAR_4271|M.marinum_M LPD--GGPLRVVVTERQLDAGG---EPSLGDLSAALTAVYGTDYGI--HS MAB_0857|M.abscessus_ATCC_1997 FE---EGWCRLAFSTGLDRLGV---EPTLEEAKEALIAIAGTDFGI--HN Mflv_5009|M.gilvum_PYR-GCK STDGRDDLWRLFVYDPSLDRKPT-DSEILDRISELVPYRTGRRVKI--GD MUL_0979|M.ulcerans_Agy99 VEP---DLVGVAILSRQR--------PEIDWFPWLAQQLRGASPG----- MLBr_02276|M.leprae_Br4923 GWIFPLGNGEVNIGVGALSTSKRPADLALRSLISYYTDLRRHEWGFSGQP . : : Mb1780|M.bovis_AF2122/97 -SFLPRFSPGKGLGVIPREGYFQIA------YLGPKGTDAQLRERGIEEF Rv1751|M.tuberculosis_H37Rv -SFLPRFSPGKGLGVIPREGYFQIA------YLGPKGTDAQLRERGIEEF TH_1880|M.thermoresistible__bu PRWLSRFGDATRLAERYRAGRVFLAGDAAHVHPPAGGQGLNLGIQDAFNL MSMEG_2252|M.smegmatis_MC2_155 PRWLSRFGDGTRLADRYRTGRVLLAGDAAHVHPPVGGQGLNLGVQDAFNL MAV_2736|M.avium_104 PRWISRFTDAARQAARYRDRRVLLAGDAAHIHHPVGGQGLNTGVQDAVNL Mvan_2422|M.vanbaalenii_PYR-1 PTSISRFTDTARQAVAYRSGRILLVGDAAHVHHPVGGQGLNTGMQDAVNL MMAR_4271|M.marinum_M PTWISRFTDLTRQAATYRQGRVLIAGDAAHVHDPVGGQGLNTGVQDAVNL MAB_0857|M.abscessus_ATCC_1997 PRWISRFSDMTRQADRYRDGRVFLAGDSAHIHFPFGGQGLNTGIQDAVNL Mflv_5009|M.gilvum_PYR-GCK AEWLSMFTVHRRLADTYRRGRVLIAGDAAHVHAPFGGQGMLTGIGDAENV MUL_0979|M.ulcerans_Agy99 --AARGCGPLRQVVSRRVAGRVLLVGDAAGYEDALTGEGITLAVKQAAAA MLBr_02276|M.leprae_Br4923 RAVSSALLPMGGAVSGVAGPNWMLIGDAAACVNPLNGEGIDYGLETGRLA : * . Mb1780|M.bovis_AF2122/97 RRDVSELLPEATASVAALASTDEVKHLNVKVNRLRRWHIDGLLCIGDAAH Rv1751|M.tuberculosis_H37Rv RRDVSELLPEATASVAALASMDEVKHLNVKVNRLRRWHIDGLLCIGDAAH TH_1880|M.thermoresistible__bu GWKLAAAVGGWAPDGLLDTYHAERHPVAADVLNNTRAQMELMSP-EPGPR MSMEG_2252|M.smegmatis_MC2_155 GWKLAASINGWAPDGLLDSYEAERRPVAAAVLDNTRAQMELLSP-EPGPQ MAV_2736|M.avium_104 GWKLALVVGGASPPALLDTYHAERHPVGERVLRNAIAQMALLRP-DERTR Mvan_2422|M.vanbaalenii_PYR-1 GWKLAQVVQGWSPDTLLDTYHDERQPVGARVLRNAVAQMALLRP-DDRTT MMAR_4271|M.marinum_M GWKLAQVVNRRSPESLLDTYHAERHPVAARVLRTTMAQVALRRL-DYRKK MAB_0857|M.abscessus_ATCC_1997 GWKLAAVIKGHAPDALLDTYHLERHPVAERVLHNTMAQTPLSEA-GPRID Mflv_5009|M.gilvum_PYR-GCK GFKLALVVRGLAADDLLDTYEAERRPLATQVLRGTSAITRVNVAGNPIVR MUL_0979|M.ulcerans_Agy99 VRAIADNDP--------ASYEAAWHRVTRSYRWLTRGLVLASAP-RPARR MLBr_02276|M.leprae_Br4923 AELLDLRDLSYVWPSLLQQHYGRGFSVAR--------RLALLLTFKRCLP : : Mb1780|M.bovis_AF2122/97 AMSPVAG-VGINLAVQDAVAAATILAEPLREHR----VSSRHLAAVRRRR Rv1751|M.tuberculosis_H37Rv AMSPVAG-VGINLAVQDAVAAATILAEPLREHR----VSSRHLAAVRRRR TH_1880|M.thermoresistible__bu AVRWLLA-ELMDFEEVNRYLTEKITAIGVRYHT----MGDGHGLLGRRMR MSMEG_2252|M.smegmatis_MC2_155 AVRRLLA-QLMAFEEVNRYLTEMITATGIRYD-----FGAEDDLVGRRLR MAV_2736|M.avium_104 ALRDLVT-ELLGMDEPRKRFAAMISGLDVRYD-----LGPGHPLLGRRMP Mvan_2422|M.vanbaalenii_PYR-1 VLHGVVS-DMLDMDEPRRRFAAMMSGLDIHYD-----LGDGHPLLGLRMP MMAR_4271|M.marinum_M ALSDTIS-ELLMMDEPRKRFAAMMSGLDIRYH-----LGGGHPLLGRRMP MAB_0857|M.abscessus_ATCC_1997 ALRDIVA-DLLAMDEPRKRIAGMMSGLDIHYM-----LGDGHQLLGRRMP Mflv_5009|M.gilvum_PYR-GCK FLRDRVAPRVFGLPAVQRWTTYTASQLWVSYRNGPLGGRGSKPRPGDRID MUL_0979|M.ulcerans_Agy99 AIVPACALLPPVFPVWGKYPGKLTAQSGGHQAD--AAHPGHRLIPAPPKP MLBr_02276|M.leprae_Br4923 AIGPSAMRSTSLITIAVRVMANLVTDDDADWVARVWRSGGWASWLVDRRP : : Mb1780|M.bovis_AF2122/97 AFPTAVTQAVQRVLHRRLLG-PLLQGRDPTPPAALLGLVERLPWLSAVP- Rv1751|M.tuberculosis_H37Rv AFPTAVTQAVQRVLHRRLLG-PLLQGRDPTPPAALLGLVERLPWLSAVP- TH_1880|M.thermoresistible__bu DIPLTGG----RLYARMHAGRGVLLDRTG--TLSVSGWADRVDHIVD--- MSMEG_2252|M.smegmatis_MC2_155 DIRLRRG----RLYELTRTGRGLLLDQTG--QLSAAGWSDRVDHVVD--- MAV_2736|M.avium_104 DLDLVTADGASRVFALLRNARPVLLNFAGAGRRSVAGWADRVRVVDAKCV Mvan_2422|M.vanbaalenii_PYR-1 DLDLETAHGPTRVSALLRQARPVLLDLGAPDAVDLTGWEARVRMVRANAA MMAR_4271|M.marinum_M DLDLTTADGPRRVFTHLHAARPVLLNLAEPGRFDIAGWRHRVLLIDAKYV MAB_0857|M.abscessus_ATCC_1997 DLDVVTADGAVRVYEHLHTARPVLFNFGARQILNVEGWEDRVHVVDAKYS Mflv_5009|M.gilvum_PYR-GCK DAPCSRPDGTATRLHGELGGRWALLLPRGVPAVGAAAVRGPAGYLADH-- MUL_0979|M.ulcerans_Agy99 SLPARIQIGPIPSAAHCQPSAPGVPLLPSAPAAPLPNWPYPP-------- MLBr_02276|M.leprae_Br4923 PFS----------------------------------------------- Mb1780|M.bovis_AF2122/97 -----------AYFVGVGVRPEHAPAFARRGPGNRKGP------------ Rv1751|M.tuberculosis_H37Rv -----------AYFVGVGVRPEHAPAFARRGPGNRKGP------------ TH_1880|M.thermoresistible__bu -------PGAALDVPAVLLRPDGHVAWVGADHPGQQDLTARLSRWFGAPA MSMEG_2252|M.smegmatis_MC2_155 -------VSDELDVPAVLLRPDGHIAWVGDE---QGDLEGCLVRWFGVPA MAV_2736|M.avium_104 ADWELPVLGRVSAPPAVLIRPDGHVAWAGDP--NDPGLHDALTTWCGPPA Mvan_2422|M.vanbaalenii_PYR-1 TVWELPVIGEVPAPAAVLIRPDGHVAWVAGD--SAAAPAEAAARWFGAPT MMAR_4271|M.marinum_M GVWELPVLGAIAAPAAALIRPDGYVAWVGDDL-TDRGLFDALTAWFGRPA MAB_0857|M.abscessus_ATCC_1997 GIWELPVLGEVSAPDAVLVRPDGYVAWVGEG--SADGLRGALTRWVGSPS Mflv_5009|M.gilvum_PYR-GCK -----VVTLHHDRDDVMLVRPDAHLAWRGAHD-DPTGLDRWLATALHPGG MUL_0979|M.ulcerans_Agy99 ----------APPEAAPPPAPPGPPG------------------------ MLBr_02276|M.leprae_Br4923 -------------------------------------------------- Mb1780|M.bovis_AF2122/97 ----------- Rv1751|M.tuberculosis_H37Rv ----------- TH_1880|M.thermoresistible__bu ----------- MSMEG_2252|M.smegmatis_MC2_155 ----------- MAV_2736|M.avium_104 AGG-------- Mvan_2422|M.vanbaalenii_PYR-1 GRR-------- MMAR_4271|M.marinum_M VPSPRLRASAP MAB_0857|M.abscessus_ATCC_1997 RA--------- Mflv_5009|M.gilvum_PYR-GCK TQ--------- MUL_0979|M.ulcerans_Agy99 ----------- MLBr_02276|M.leprae_Br4923 -----------