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PRVTDDHLAARRRQILDGARRCFAKYGYESATVRRLEETIGLSRGAIFHHFKDKDTLFFELAREDAERMA EVAAREGLIQVMRDLLAAPEQYDWLATRLEIARKLRNDPDFHRGWAERSAELTAATTERLRRQKQAGRLR DDVPSAVLHIYLDVVLDGLVARLASGEDSKNLSAVLDLVEASVRQQPKPAPAVSTDHSFSDES*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_3142 | - | - | 100% (204) | HTH-type transcriptional repressor AcnR |
| M. smegmatis MC2 155 | MSMEG_1565 | - | 4e-11 | 25.88% (170) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_0148 | - | 1e-08 | 43.94% (66) | transcriptional regulator, TetR family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1510c | - | 1e-84 | 81.18% (186) | transcriptional regulatory protein |
| M. gilvum PYR-GCK | Mflv_3666 | - | 4e-90 | 87.63% (186) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv1474c | - | 1e-84 | 81.18% (186) | transcriptional regulatory protein |
| M. leprae Br4923 | MLBr_00717 | - | 2e-05 | 28.81% (59) | putative TetR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_2731 | - | 6e-81 | 77.96% (186) | TetR family transcriptional regulator |
| M. marinum M | MMAR_2281 | - | 5e-84 | 80.11% (186) | transcriptional regulatory protein |
| M. avium 104 | MAV_3305 | - | 6e-82 | 79.03% (186) | HTH-type transcriptional repressor AcnR |
| M. thermoresistible (build 8) | TH_0251 | - | 9e-89 | 86.96% (184) | PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN |
| M. ulcerans Agy99 | MUL_1483 | - | 1e-84 | 80.65% (186) | transcriptional regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_2744 | - | 2e-89 | 86.10% (187) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1510c|M.bovis_AF2122/97 -MPKVSEDHLAARRRQILDGARRCFAEYGYDKATVRRLEQAIGMSRGAIF
Rv1474c|M.tuberculosis_H37Rv -MPKVSEDHLAARRRQILDGARRCFAEYGYDKATVRRLEQAIGMSRGAIF
MMAR_2281|M.marinum_M -MPKVSEDHLAARRRQILDGARRCFAEYGYDKATVRRLEQAIGMSRGAIF
MUL_1483|M.ulcerans_Agy99 -MPKVSEDHLAARRRQILDGARRCFAEYGYDKATVRRLEQAIGMSRGAIF
MAV_3305|M.avium_104 -MPKVSEDHLAARRRQILDGARRCFAEFGYDKATVRRLEQAIGMSRGAIF
MSMEG_3142|M.smegmatis_MC2_155 -MPRVTDDHLAARRRQILDGARRCFAKYGYESATVRRLEETIGLSRGAIF
TH_0251|M.thermoresistible__bu ----VTDDHLAARRRQILDGARRCFAEYGYEQATVRRLEQATGLSRGAIF
Mflv_3666|M.gilvum_PYR-GCK -MPRVTDDHLAARRRQILDGARRCFAEYGYESATVRRLEQTIGLSRGAIF
Mvan_2744|M.vanbaalenii_PYR-1 -MPRVTDDHLAARRRQILDGARRCFAEYGYDRATVRRLEQTIGLSRGAIF
MAB_2731|M.abscessus_ATCC_1997 -MPRVSEDHLAARRRQILDGARRCFAEYGYDGATVRRLEHTIGMSRGAIF
MLBr_00717|M.leprae_Br4923 MTTARRRLSPEDRRAELLALGAEVFGKRPYDEVRIDEIAERAGVSRALMY
** ::* . . *.: *: . : .: . *:**. ::
Mb1510c|M.bovis_AF2122/97 HHFRDKDALFFALAREDTERMAAVASR---EGLIGVMRDMLAAPDQFDWL
Rv1474c|M.tuberculosis_H37Rv HHFRDKDALFFALAREDTERMAAVASR---EGLIGVMRDMLAAPDQFDWL
MMAR_2281|M.marinum_M HHFRDKDALFFALAHEDAERMADVASR---EGLIQVMRDMLAAPDQFDWL
MUL_1483|M.ulcerans_Agy99 HHFRDKDALFFALAHEDAERMADVASR---EGLIQVMRDMLAAPEQFDWL
MAV_3305|M.avium_104 HHFRDKDALFFALAHEDAERMAEVASR---AGLIQVMRDMLAAPDQFDWL
MSMEG_3142|M.smegmatis_MC2_155 HHFKDKDTLFFELAREDAERMAEVAAR---EGLIQVMRDLLAAPEQYDWL
TH_0251|M.thermoresistible__bu HHFKDKDTLFFELAREDAERMAEVASR---EGLIQVMRDLIAAPEQYDWL
Mflv_3666|M.gilvum_PYR-GCK HHFRDKDTLFFELAREDAERMADVAAR---EGLIQVMRDMLAAPDQFDWL
Mvan_2744|M.vanbaalenii_PYR-1 HHFRDKDTLFFELAREDAERMADVAAR---EGLIQVMRDMLAAPDQFNWL
MAB_2731|M.abscessus_ATCC_1997 HHFRDKDTLFFALAREDAERMANVASR---EGLVQVMRDMLADPSQFDWL
MLBr_00717|M.leprae_Br4923 HYFPDKRAFFAAVVKDEADRLYAATNIPPPAGLTMFEEVRVGVLAYMAYH
*:* ** ::* :.:::::*: .: ** . . :. :
Mb1510c|M.bovis_AF2122/97 ATRLEIARKL-----RNDPDFS---RGWAERSAELAAATTDRLRRQKQAN
Rv1474c|M.tuberculosis_H37Rv ATRLEIARKL-----RNDPDFS---RGWAERSAELAAATTDRLRRQKQAN
MMAR_2281|M.marinum_M ATRLEIARKL-----RNDPEFS---RGWAERSAELAAATTDRLRRQKQAN
MUL_1483|M.ulcerans_Agy99 ATRLEIARKL-----RNDPEFS---RGWAERSAELAAATTDRLRRQKQAN
MAV_3305|M.avium_104 ATRLEIARKL-----RNDPAFS---RGWAERSAELAAATTDRLRRQTEAH
MSMEG_3142|M.smegmatis_MC2_155 ATRLEIARKL-----RNDPDFH---RGWAERSAELTAATTERLRRQKQAG
TH_0251|M.thermoresistible__bu TTRLEIARKL-----RNDPEFH---RGWSELSAELAAATTARLRRQKQAG
Mflv_3666|M.gilvum_PYR-GCK ATRLEIARKL-----RNDPAFS---QGWAERSAELSAATTERLRRQKQAG
Mvan_2744|M.vanbaalenii_PYR-1 ATRLEIARKL-----RNDPAFS---RGWAERSAELSAATTERLRRQKRAG
MAB_2731|M.abscessus_ATCC_1997 ATRLEIARKL-----RNDPEFR---RGWNQRSEELNTATLARLQRQKKAG
MLBr_00717|M.leprae_Br4923 KQNPEAAWAAYVGLGRSDPVLLGIDDEAKNRQMEHIMSRIGDVVSVVPES
. * * *.** : : . * : :
Mb1510c|M.bovis_AF2122/97 RVRDDVP---SDVLRCYLDLVLDGLLARLAS-GEDPQRLA-----AVLDL
Rv1474c|M.tuberculosis_H37Rv RVRDDVP---SDVLRCYLDLVLDGLLARLAS-GEDPQRLA-----AVLDL
MMAR_2281|M.marinum_M RVRDDVP---NEVLQCYLDLVLDGLVARLAS-GEDPQRLT-----DVLDL
MUL_1483|M.ulcerans_Agy99 RVRDDVP---NEVLQCYLDLVLDGLVARLAS-GEDPQRLT-----DVLDL
MAV_3305|M.avium_104 RVRDDVP---GDVLQCYLELVLDGLVARLAS-GEDPQRLS-----AVLDL
MSMEG_3142|M.smegmatis_MC2_155 RLRDDVP---SAVLHIYLDVVLDGLVARLAS-GEDSKNLS-----AVLDL
TH_0251|M.thermoresistible__bu RLRDDVP---GEVLRTYLELVLDGLVARLAS-GDDPEKLS-----AVLDL
Mflv_3666|M.gilvum_PYR-GCK RLRDDVD---GEVLRTYLELVLDGLVARLAS-GDDPEKLS-----AVLDL
Mvan_2744|M.vanbaalenii_PYR-1 RLRDDVP---GDVLRTYLELVLDGLVARLAS-GDDPEKLG-----AVLDL
MAB_2731|M.abscessus_ATCC_1997 RLREDVP---SEVILGYLDLVLDGLVARLAA-GESTESLS-----RVLDL
MLBr_00717|M.leprae_Br4923 KLHPDIERDLRVIVHGWLAFTFEVCRQRIMDPSTDADRLADSCAHALLDA
::: *: :: :* ..:: *: . ... * :**
Mb1510c|M.bovis_AF2122/97 VENSVRRS-----------------
Rv1474c|M.tuberculosis_H37Rv VENSVRRS-----------------
MMAR_2281|M.marinum_M VENSLRRS-----------------
MUL_1483|M.ulcerans_Agy99 VENSLRRS-----------------
MAV_3305|M.avium_104 VENSVRRNDSRPG------------
MSMEG_3142|M.smegmatis_MC2_155 VEASVRQQPKPAPAVSTDHSFSDES
TH_0251|M.thermoresistible__bu VEASVRHQGSE--------------
Mflv_3666|M.gilvum_PYR-GCK VEASVRQP-----------------
Mvan_2744|M.vanbaalenii_PYR-1 VEASVRQQ-----------------
MAB_2731|M.abscessus_ATCC_1997 VEDSVRRADHA--------------
MLBr_00717|M.leprae_Br4923 IARVPEISKELADAMAIARQPPQ--
: .