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VRIPRPHPSAKPGVKVDARSERWREHRKKVRNEIVDAAFRAIDRLGPELSVRQIAEEAGTAKPKIYRHFT DKSDLLEAIGMRLRDMLWAAIFPSLDLATDSAREVIRRSVEEYVNLVDQHPNVLRVFIQGRSAKQSEATV RTLNEGREITLAMAEMFNNELREMELNRAALELAAFAAFGSAASATEWWLGPEPDSPRRMPREQFVAHLT TIMMGVIVGTAEALGIAVDPDQPIHDAVPNNPAVR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv3050c | - | - | 100% (246) | PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY ASNC-FAMILY) |
| M. tuberculosis H37Rv | Rv0472c | - | 1e-21 | 30.23% (215) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0302 | - | 1e-08 | 27.42% (186) | TetR/ACRR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3076c | - | 1e-139 | 100.00% (246) | AsnC family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_4290 | - | 2e-96 | 68.16% (245) | TetR family transcriptional regulator |
| M. leprae Br4923 | MLBr_01733 | - | 1e-118 | 86.25% (240) | putative TetR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_2968 | - | 6e-47 | 41.71% (211) | TetR family transcriptional regulator |
| M. marinum M | MMAR_1643 | - | 1e-121 | 88.21% (246) | AsnC family transcriptional regulator |
| M. avium 104 | MAV_3917 | - | 1e-113 | 81.45% (248) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_2309 | - | 1e-102 | 76.57% (239) | transcriptional regulatory protein |
| M. thermoresistible (build 8) | TH_1826 | - | 2e-96 | 76.23% (223) | PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY |
| M. ulcerans Agy99 | MUL_1879 | - | 1e-118 | 86.99% (246) | AsnC family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_2056 | - | 2e-98 | 69.80% (245) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4290|M.gilvum_PYR-GCK -----------------------------MRRGSRARAAEETGVKVDARS
Mvan_2056|M.vanbaalenii_PYR-1 ----------------------MAGYSDRVRRGSRARAAEEPGVKVDARS
MSMEG_2309|M.smegmatis_MC2_155 -----------------------------MRRGSRSHSGG-PGVKVDARS
TH_1826|M.thermoresistible__bu ---------------------------------------------VDARS
Rv3050c|M.tuberculosis_H37Rv -----------------------------MVRIPRPHPSAKPGVKVDARS
Mb3076c|M.bovis_AF2122/97 -----------------------------MVRIPRPHPSAKPGVKVDARS
MMAR_1643|M.marinum_M -----------------------------MRRISRPHPNADAGVKVDARS
MUL_1879|M.ulcerans_Agy99 -----------------------------MRRISRAHLNADAGVKVDARS
MLBr_01733|M.leprae_Br4923 MTRRSIHTRKPLKWSGCAGQHVRSGKVFDVGRISLSYPSMKPGVKIDARS
MAV_3917|M.avium_104 --------------------------MVRMPRPARPHSATKPGAKVDARS
MAB_2968|M.abscessus_ATCC_1997 -------------------------------------MSTAIASKAAPVA
. :
Mflv_4290|M.gilvum_PYR-GCK ERWREHRKKVRSEIVDAAFRAIDRLGPEVSLREIAEEAGTAKPKIYRHFT
Mvan_2056|M.vanbaalenii_PYR-1 ERWREHRKKVRSEIVDAAFRAIDRLGPEVSLREIAEEAGTAKPKIYRHFT
MSMEG_2309|M.smegmatis_MC2_155 ERWREHRKKVRSEIVDAAFRAIDRLGPELSLREIAEEAGTAKPKIYRHFT
TH_1826|M.thermoresistible__bu ERWREHRKKVRAEIVDAAYRAIDRLGPELSLREIAAEAGTAKPKIYRHFT
Rv3050c|M.tuberculosis_H37Rv ERWREHRKKVRNEIVDAAFRAIDRLGPELSVRQIAEEAGTAKPKIYRHFT
Mb3076c|M.bovis_AF2122/97 ERWREHRKKVRNEIVDAAFRAIDRLGPELSVRQIAEEAGTAKPKIYRHFT
MMAR_1643|M.marinum_M ERWREHRKKVRNEIVEAAFRAIDRLGPELSVREIAEEAGTAKPKIYRHFT
MUL_1879|M.ulcerans_Agy99 ERWREHRKKVRNEIVEAAFRAIDRLGPELSVREIAEEAGTAKPKIYRHFT
MLBr_01733|M.leprae_Br4923 ERWREHRKKVRGEIVDAAFRALDRLGPEVSVREIAEEAGTAKPKIYRHFT
MAV_3917|M.avium_104 ERWREHRKKVRNEIVDAAFRAIDRLGPELSVREIAEEAGTAKPKIYRHFH
MAB_2968|M.abscessus_ATCC_1997 ARRGDRRKVAREELLDAAFRAIDGLGATVSMDDIAREAGVAKPKLYRYFE
* ::** .* *:::**:**:* **. :*: :** ***.****:**:*
Mflv_4290|M.gilvum_PYR-GCK DKADLFQAIGQRMRDMLWAAIFPSIDISTDPARTVVFRAVEQYVRLVDEH
Mvan_2056|M.vanbaalenii_PYR-1 DKSDLFQAIGQRMRDMLWAAIFPSINISTDAARTVVFRAVEQYVRLVDEH
MSMEG_2309|M.smegmatis_MC2_155 DKSDLFQAIGERLRDMLWSAIFPSINLASDPAREVIRRSVEQYVRLVDEH
TH_1826|M.thermoresistible__bu DKADLHQAIGQRLRDMLWAAIFPSIDLSADSGREIIRRSVEQYVRLVDQH
Rv3050c|M.tuberculosis_H37Rv DKSDLLEAIGMRLRDMLWAAIFPSLDLATDSAREVIRRSVEEYVNLVDQH
Mb3076c|M.bovis_AF2122/97 DKSDLLEAIGMRLRDMLWAAIFPSLDLATDSAREVIRRSVEEYVNLVDQH
MMAR_1643|M.marinum_M DKSDLFVAIGERLRDMLWTSIFPSINLATDSAREVIRRSVEEYVSLVDKH
MUL_1879|M.ulcerans_Agy99 DKSDLFVAIRERLRDMLWTSIFPSINLATDSAREVIRRSVEEYVSLVDKH
MLBr_01733|M.leprae_Br4923 DKSDLFEAIGIRLRDMLWAAIFPAIDLATDSAREIIRRSVDEYVSLVDKH
MAV_3917|M.avium_104 DKSDLFQAIGERLRDMLWTAIFPSIDLKTDSAREVIRRSVEEYVTLVDKH
MAB_2968|M.abscessus_ATCC_1997 DKADLHSAVLERVQDMLWSASMDRINLMTDSARDLVEHGANEYAQMISDH
**:** *: *::****:: : ::: :*..* :: :..::*. ::..*
Mflv_4290|M.gilvum_PYR-GCK PNVVRFLMQGRFAEQTESAMRALNEGRDITLAMADMFNNELKDMQLDYAA
Mvan_2056|M.vanbaalenii_PYR-1 PNVVRFLMQGRFAEQSESAMRALNEGRDITLGIAEMFNNELSDMELDNAA
MSMEG_2309|M.smegmatis_MC2_155 PNVLRFLIQGRFAEQSESTMRALNEGRGITLAMADMFSHELREMELDGAA
TH_1826|M.thermoresistible__bu PNVLRFLLQGRFADQSASAARALNEGRDITLAMADMFDNELREIELDPTA
Rv3050c|M.tuberculosis_H37Rv PNVLRVFIQGRSAKQSEATVRTLNEGREITLAMAEMFNNELREMELNRAA
Mb3076c|M.bovis_AF2122/97 PNVLRVFIQGRSAKQSEATVRTLNEGREITLAMAEMFNNELREMELNRAA
MMAR_1643|M.marinum_M PNVLRVFIQGRFATQSEATVRTLNEGREITLTFAEMFNNELREMELNRAA
MUL_1879|M.ulcerans_Agy99 PNVLRVFIQGRFATQSEATVRTLNEGREITLTFAEMFNNELREMELNRAA
MLBr_01733|M.leprae_Br4923 PNVLRVFIQGRFSAQSEATVRTLDEGREITLTMAEMFNNELREMELNRAA
MAV_3917|M.avium_104 PNVLRVFIQGRSTGTPQSTVTILNEGREITLAMADLFDNELREMELDHAA
MAB_2968|M.abscessus_ATCC_1997 PNVLRFIVHGHFINSSDGTERLVETAQQMTHDIAEILSSAIDDETVDIDD
***:*.:::*: . .: :: .: :* :*:::. : : ::
Mflv_4290|M.gilvum_PYR-GCK FELAGFATFGAAASATDWWLGAERDSPRRLPSEKFVDYLTKIMVGSINGT
Mvan_2056|M.vanbaalenii_PYR-1 FELAGFATFGAAASATDWWLGAEQDSPRRLPSEKFVDYLTTIMVGSINGT
MSMEG_2309|M.smegmatis_MC2_155 IELAAFATFGAAASATDWWLGSKEDSPRRMPADEFVNHLTTIMVGSINGT
TH_1826|M.thermoresistible__bu LELAAHAAFGSIASATDWWLGAETDSPRRMPSDQFIAHLTTITVGAINGT
Rv3050c|M.tuberculosis_H37Rv LELAAFAAFGSAASATEWWLGPEPDSPRRMPREQFVAHLTTIMMGVIVGT
Mb3076c|M.bovis_AF2122/97 LELAAFAAFGSAASATEWWLGPEPDSPRRMPREQFVAHLTTIMMGVIVGT
MMAR_1643|M.marinum_M FELAAFAAFGSAASATEWWLGPEPDSPRRMPHDQFVAHLTTIMMGVIVGT
MUL_1879|M.ulcerans_Agy99 FELAAFAAFGSAASATEWWLGPEPDSPRRMPHDQFVAHLTTIMMGVIVGT
MLBr_01733|M.leprae_Br4923 SELAAFAAFGSVASATEWWLGPEPDSPRRMPREQFVAHLTIIMMAVIVGT
MAV_3917|M.avium_104 VELAAHAAFGSAASATEWWLGPEPDSPRLMSRAQFVAHLSTIMMAVIIGT
MAB_2968|M.abscessus_ATCC_1997 ADLAVSSAAGAIGTATEWFLGPNQLRADPMPIERFVEYLTTVLSGLAASI
:** :: *: .:**:*:**.: . :. .*: :*: : . .
Mflv_4290|M.gilvum_PYR-GCK CEVLGVKIDPDVPLHEGVTRREQVA-
Mvan_2056|M.vanbaalenii_PYR-1 CEVLGIKIDPDVPLHEGVKRREQVA-
MSMEG_2309|M.smegmatis_MC2_155 CELLGIRIDPDLPLHEGVQRRERAS-
TH_1826|M.thermoresistible__bu CEMLGIKIDPDLPLHAGVRRREDVA-
Rv3050c|M.tuberculosis_H37Rv AEALGIAVDPDQPIHDAVPNNPAVR-
Mb3076c|M.bovis_AF2122/97 AEALGIAVDPDQPIHDAVPNNPAVR-
MMAR_1643|M.marinum_M AEALGIAMDPDKPIHDAVPAPTADRR
MUL_1879|M.ulcerans_Agy99 AEALGIAMDPDKPIHDAVPAPTADRR
MLBr_01733|M.leprae_Br4923 AETLGISMNPDRPIHDAVPLDRSAS-
MAV_3917|M.avium_104 AETLGITMNPDQPIHDAVVRKPAVS-
MAB_2968|M.abscessus_ATCC_1997 AEFNGLTLDPDQPLHLAFTRIQGGAS
.* *: ::** *:* ..