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aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_4447 | - | - | 100% (436) | PPE protein |
| M. thermoresistible (build 8) | TH_4387 | - | 3e-43 | 39.53% (301) | PUTATIVE putative PPE family protein |
| M. thermoresistible (build 8) | TH_3569 | - | 2e-38 | 43.69% (206) | PUTATIVE PPE protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3903 | PPE68 | 2e-93 | 45.31% (437) | PPE family protein |
| M. gilvum PYR-GCK | Mflv_0768 | - | 1e-134 | 57.95% (440) | PPE protein |
| M. tuberculosis H37Rv | Rv3873 | PPE68 | 2e-93 | 45.31% (437) | PPE family protein |
| M. leprae Br4923 | MLBr_01828 | PPE | 2e-28 | 42.21% (154) | PPE-family protein |
| M. abscessus ATCC 19977 | MAB_2230c | - | 3e-36 | 29.17% (456) | PPE family protein |
| M. marinum M | MMAR_5448 | - | 1e-90 | 45.79% (439) | PPE family protein |
| M. avium 104 | MAV_2429 | - | 6e-38 | 30.34% (468) | PPE family protein |
| M. smegmatis MC2 155 | MSMEG_0064 | - | 1e-146 | 61.87% (438) | PPE family protein |
| M. ulcerans Agy99 | MUL_1202 | - | 2e-38 | 30.43% (447) | PPE family protein |
| M. vanbaalenii PYR-1 | Mvan_0077 | - | 1e-137 | 58.86% (440) | PPE protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3903|M.bovis_AF2122/97 ---------MLWHAMPPELNTARLMAGAGPAPMLAAAAGWQTLSAALDAQ
Rv3873|M.tuberculosis_H37Rv ---------MLWHAMPPELNTARLMAGAGPAPMLAAAAGWQTLSAALDAQ
MMAR_5448|M.marinum_M ---------MLWHAMPPELNTARLMAGAGPAPMLAAAAGWEALAAALDAQ
Mflv_0768|M.gilvum_PYR-GCK MANIGIPVPPSWVAFPPEINTSRLQAGAGAVPMLQAAAGWEAFAISLETQ
Mvan_0077|M.vanbaalenii_PYR-1 MATIGIPIPPIWGAFPPEINTSRLQAGAGAVPMLQAAAGWEAFAISLETQ
TH_4447|M.thermoresistible__bu ---------MFWHAMPPEVNTSRLMAGAGTAPMLQAAAGWEAFAISLETQ
MSMEG_0064|M.smegmatis_MC2_155 ----------MWIALPPEINTARLMVGAGPAPMLQAAAGWEGLAVLLETQ
MAV_2429|M.avium_104 ------MTAPVWIAFPPEVHSTLLSSGPGPAPLLAAATAWSSMSTEYAAA
MUL_1202|M.ulcerans_Agy99 ----------MWFTSPPEVHSALLSSGPGPASLLSGAAAWAGLSTEYASV
MAB_2230c|M.abscessus_ATCC_199 ------MSAPIWMASPPEVHSALLSAGPGPGALLAAAAQWQALSVQYTTA
MLBr_01828|M.leprae_Br4923 ------MSAPIWMASPPEVHSALLSRGPGSGPLLVAAEAWRSLSSVYAEM
* : ***:::: * *.*. .:* .* * ::
Mb3903|M.bovis_AF2122/97 AVELTARLNSLG-EAWTGGGSDKALAAATPMVVWLQTASTQAKTRAMQAT
Rv3873|M.tuberculosis_H37Rv AVELTARLNSLG-EAWTGGGSDKALAAATPMVVWLQTASTQAKTRAMQAT
MMAR_5448|M.marinum_M AVELTARLNSLG-EAWTGGGSEKALAAALPMVTWLQTASTQAKTRGLQAG
Mflv_0768|M.gilvum_PYR-GCK ADELASSLASLS-QNWQGMASERAVTAAMPMVLWLRMLSLQAHKRALQAS
Mvan_0077|M.vanbaalenii_PYR-1 ADELAASLATLS-QMWQGTASERAVMATMPMVMWLRMLSLQAQKRAAQAS
TH_4447|M.thermoresistible__bu ADELAGSLAALA-GAWTGGASERAIAAITPMIVWLRTVSAQAHKRSAQAL
MSMEG_0064|M.smegmatis_MC2_155 AAELAAALTNLT-SVWTGAASERAVAATMPMITWLQTTAAQAQKRALQAS
MAV_2429|M.avium_104 AAELDGLLAAAHAGAWEGPSAEQYVAAHAPYQAWLLESAAKSSTAASLHE
MUL_1202|M.ulcerans_Agy99 ADELMGVLAAVQGGAWEGLSAELYVAAHVPYLMWLMRASATSAQAAAQHE
MAB_2230c|M.abscessus_ATCC_199 ATELTQLLAATGSGSWQGPSAAQYVASHAPYLAWLTQQSAMSATNAVLHE
MLBr_01828|M.leprae_Br4923 ADELVALLVVVPVSSWDGSAAEAYVIAYLPYLGWLRQASVDSAVMAAHYE
* ** * * * .: : : * ** : : .
Mb3903|M.bovis_AF2122/97 AQAAAYTQAMATTPSLPEIAANHITQAVLTATNFFGINTIPIALTEMDYF
Rv3873|M.tuberculosis_H37Rv AQAAAYTQAMATTPSLPEIAANHITQAVLTATNFFGINTIPIALTEMDYF
MMAR_5448|M.marinum_M AQAAAYMQAMATTPSLPEIFANHITNVILNATNFFGINTVPIAFNEMDYF
Mflv_0768|M.gilvum_PYR-GCK AQASSWTVAATGTPQLPEIELNHVTNATLHATNFLGVNGIPIALNEADY-
Mvan_0077|M.vanbaalenii_PYR-1 AQATAWASAATSTPQLPEIETNHITNAVLNATNFLGVNTVPIAVNEADY-
TH_4447|M.thermoresistible__bu AQAAAYSTAMATTPPLAEIEQNHITRAVLHATNFLGINTVPIGINEMDYF
MSMEG_0064|M.smegmatis_MC2_155 AQASSYSLALATTPPLPEIEQNHITHGVLEATNFLGINTVPIALNEMDYF
MAV_2429|M.avium_104 TAAGAYTAALAAMPTLGELATNHAVHGALVATNFFGINTIPIAVNEADY-
MUL_1202|M.ulcerans_Agy99 AAAAAYTTALAAMPTMPELAANHVIHGVLMATNFFGINTIPIAANEADY-
MAB_2230c|M.abscessus_ATCC_199 TSAAAYTTALAAMPTLAELAANHMIHGVLLATNFFGINTIPIALNEADY-
MLBr_01828|M.leprae_Br4923 TMATAYITTLAMMPTLAELAANRTAHTVLVTTNFFGINTIPIARNEIDY-
: * :: : : * : *: *: . * :***:*:* :**. .* **
Mb3903|M.bovis_AF2122/97 IRMWNQAALAMEVYQAETAVNTLFEKLEPMASILDPGASQST--------
Rv3873|M.tuberculosis_H37Rv IRMWNQAALAMEVYQAETAVNTLFEKLEPMASILDPGASQST--------
MMAR_5448|M.marinum_M VRMWNQAALAMDVYQAETTANTLFEQLEPMTSILDPATAQSMPT------
Mflv_0768|M.gilvum_PYR-GCK IRMWNQAAAVMTAYETETVLNTTFEPVAPPKPIAVPPGSEAAFAGAMSGA
Mvan_0077|M.vanbaalenii_PYR-1 IRMWNQAAAVMTGYETETILNSTFEPVAPPKPITVFGSTQAAMATAIGSA
TH_4447|M.thermoresistible__bu VRMWNQAAGAMDVYQAETAMNILFEPIMPMKPIVIPGVGEAAVAGALGKA
MSMEG_0064|M.smegmatis_MC2_155 VRMWNQAAGAMDVYHAETTVNLLFEPIMPMKPIVLPGVGETTAAAALAQT
MAV_2429|M.avium_104 ARMWVQAATTMSTYQAVSQSALAAVPPTTPAPTIVAPGTEAGTATAAAVQ
MUL_1202|M.ulcerans_Agy99 VRMWIQAATTMSTYQAVSAAAVASTPPSTPAPRILAAPAAAHDHDHDHGG
MAB_2230c|M.abscessus_ATCC_199 IRMWIQAATTMGVYQGVSTAAVTSVAPTPPAPTIMAPGGEMSRMSADMSG
MLBr_01828|M.leprae_Br4923 VRMWVEAAIAMGTYQEVSTVVVDSAPEAIAAPQIMASDALEASSDQPSPT
*** :** .* *. : .
Mb3903|M.bovis_AF2122/97 ---------------------------TNPIFGMPSPGSSTPVG------
Rv3873|M.tuberculosis_H37Rv ---------------------------TNPIFGMPSPGSSTPVG------
MMAR_5448|M.marinum_M --------S------------------STPLLDMASQVTGIPSS------
Mflv_0768|M.gilvum_PYR-GCK VPGAGEAVM------------------RNAIISKVSSTAKLDTANQIAG-
Mvan_0077|M.vanbaalenii_PYR-1 APGIASAAA------------------RNATFTKVSVVGKLDEVNQKAG-
TH_4447|M.thermoresistible__bu AAMAPAAAA------------------RDLVFAKVSAQATVESAALQAGR
MSMEG_0064|M.smegmatis_MC2_155 APRVAEGVM------------------RNAVIEGVSAIATIESVGLAAG-
MAV_2429|M.avium_104 SAAAAPATD------------------SGSNLNHADTSSTQQQASTAAQS
MUL_1202|M.ulcerans_Agy99 DPTPIDYFV------------------AEVLRIISGGRIIWDPAEGTVNG
MAB_2230c|M.abscessus_ATCC_199 MAAQAQAAE------------------SGMALDDSES-------------
MLBr_01828|M.leprae_Br4923 APSQSPQVQNWLQWLQKIGYTDFYNTLVQPLITSLTNHPFFQGMFSGFDP
Mb3903|M.bovis_AF2122/97 --------------------------------------------------
Rv3873|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_5448|M.marinum_M --------------------------------------------------
Mflv_0768|M.gilvum_PYR-GCK ----------RAEGTLRGVVDRAGSHAEKSQG--------------LEQA
Mvan_0077|M.vanbaalenii_PYR-1 ----------HAEGLLQQAADSGRSQAEQGQL--------------LQQA
TH_4447|M.thermoresistible__bu AVAQGNMAAQRAEGTVQKTENLAHQSATRSE----------------PQQ
MSMEG_0064|M.smegmatis_MC2_155 ----------HAAAQANFAEQRGQGAAQKGEN--------------AGQE
MAV_2429|M.avium_104 YPSWQDQLTAWLKQYTQNFAWPVSKDLNPGG----------WPFPPVPFV
MUL_1202|M.ulcerans_Agy99 IP-YDDYVNAAQPIWWLVRALEFGQDFQT--------------FIKELFT
MAB_2230c|M.abscessus_ATCC_199 ---FFDKLMRQIQEFFSDPLGTLQKILQD--------------FMRNPLE
MLBr_01828|M.leprae_Br4923 WLPSLGNPLSFLSPFNIAFALGTPMDIGSYVGYLSQTFAFIGADLAAAFA
Mb3903|M.bovis_AF2122/97 -----------------QLPPAATQTLGQLGEMSG-PMQQLTQPLQQVTS
Rv3873|M.tuberculosis_H37Rv -----------------QLPPAATQTLGQLGEMSG-PMQQLTQPLQQVTS
MMAR_5448|M.marinum_M -----------------ELQQTATQ----VAEASG-PMQQLAQPAQQMTS
Mflv_0768|M.gilvum_PYR-GCK PQ----QGMQMGMQMASQLGSTLGQMPQQMMQGVTQPFQQLTQPLQQMSS
Mvan_0077|M.vanbaalenii_PYR-1 PQ----QGMQMGMQMASQLGSTLGQLPQQMMQGVTQPFQQLTQPLQQMSS
TH_4447|M.thermoresistible__bu LQ----QGVQMGMQMGSQLGSTLAQLPQQAGQMISQPMQQLTAPLQQVSS
MSMEG_0064|M.smegmatis_MC2_155 AGRESGKNMQQGMQMVMQMGSQAAQAPAQLASMFQSGVQTMTQPLQQATQ
MAV_2429|M.avium_104 NGLASFFGQLGFSPALSTALGWAIFHTLMIFWPFMQAAIQMAVVLAPVVV
MUL_1202|M.ulcerans_Agy99 N----PIGAIEFMVEL-VLFDWPT-HIAQIIQALAQSPQLLAVALGGVVA
MAB_2230c|M.abscessus_ATCC_199 A--LVAWGPLLFFIAY---EAFFIPFGFTFWGVMLSAPLWLPLLLVGLAQ
MLBr_01828|M.leprae_Br4923 SGNPVTIGFTLLFTTIEAIGTIITDTIALVKTMIEQSFVLLPMILPLLTA
:.
Mb3903|M.bovis_AF2122/97 ---LFSQVGGTGGGNPADEEAAQMGLLGTSPLSNHPLAGGSGPSAGAGLL
Rv3873|M.tuberculosis_H37Rv ---LFSQVGGTGGGNPADEEAAQMGLLGTSPLSNHPLAGGSGPSAGAGLL
MMAR_5448|M.marinum_M ---AFSNTGSSGNG--ADEEGFRMGLLGAGALSNHPLAGGSGPTTGAGLL
Mflv_0768|M.gilvum_PYR-GCK ---LFGGM--MNGD----K-GAQIGMVGATPFSNHPAIGGTGPATGSGLV
Mvan_0077|M.vanbaalenii_PYR-1 ---LFGQMGGLGGD----R-GAQIGMLGATPFSNHPAIGGSGAATGAGLV
TH_4447|M.thermoresistible__bu ---VFGQMGGMGSG----D-SAQIGLIGASPFSNHPLAGGSGPATGAGLV
MSMEG_0064|M.smegmatis_MC2_155 ---MVSQFASMGGS----ERAMQVGLMGASPFSNHPMLGGSGPSTGAGLV
MAV_2429|M.avium_104 ---AAIGAAAAGGAAAAVTAISVAAPLSMAAPVP--VAAAPAPVATVPAP
MUL_1202|M.ulcerans_Agy99 NLGAISGLAGLSGLAGLHSAALPAAIAPIAPPMPPGVALAPTVAASVAAP
MAB_2230c|M.abscessus_ATCC_199 ----LVNPVPVEADAPADEPAPQQARVERSSPQQQPFAMGGMPGGGGAPA
MLBr_01828|M.leprae_Br4923 P-LAVATAGAAGSFAGLSELAGLVGVAPPGLPSAPPVAAVAPVVPPSMPT
.
Mb3903|M.bovis_AF2122/97 RAESLPGAGGSLTRTPLMSQLIE---------------------------
Rv3873|M.tuberculosis_H37Rv RAESLPGAGGSLTRTPLMSQLIE---------------------------
MMAR_5448|M.marinum_M RGESLPGAGGTLTRTPLISELVE---------------------------
Mflv_0768|M.gilvum_PYR-GCK RAASLPGAGGSAPQTPLMSNLVGSGL------------------------
Mvan_0077|M.vanbaalenii_PYR-1 RAASLPGAGGTAARTPLMSNLVGSGL------------------------
TH_4447|M.thermoresistible__bu RAASLPGLGGTSPTTSLISNLLG-HQ------------------------
MSMEG_0064|M.smegmatis_MC2_155 RAMSLPGAGGTAPRTPLLSNLLG---------------------------
MAV_2429|M.avium_104 TIAGAPAGVSHVPTTASAPAPTMAGSAGGGP---VGGGPGVGFGPTATDG
MUL_1202|M.ulcerans_Agy99 TPPSAPPSAASTVANAAPPPPPAPAAAGFGFPFVVGGGPGIGYG------
MAB_2230c|M.abscessus_ATCC_199 TPANAPATPANAPASPAAAAATPAYMVYAVQ----EDPPAARFGPTLN--
MLBr_01828|M.leprae_Br4923 LASIPTPTPMPAPAASTAPVVTPPGPPPVTAPPSVTGAGVESFGYLVG--
. . .
Mb3903|M.bovis_AF2122/97 ----------------------------------------KPVAPSVMPA
Rv3873|M.tuberculosis_H37Rv ----------------------------------------KPVAPSVMPA
MMAR_5448|M.marinum_M ----------------------------------------KPMGPSVQPA
Mflv_0768|M.gilvum_PYR-GCK ----------------------------------------QPT-SPVAVG
Mvan_0077|M.vanbaalenii_PYR-1 ----------------------------------------QPTVSAVAVG
TH_4447|M.thermoresistible__bu ----------------------------------------NPTAAPAPTG
MSMEG_0064|M.smegmatis_MC2_155 -----------------------------------------ISGEMKAAP
MAV_2429|M.avium_104 IGAGMSDALYAVGLSGLSARGSASSRARRKSEEPAPDDLDAPAAAAAAAA
MUL_1202|M.ulcerans_Agy99 --------------EGMSASAAAS--ARRKAPE--------PDSAALAAA
MAB_2230c|M.abscessus_ATCC_199 --------------EGSGAKAPAAG-----------------ISAAAAAA
MLBr_01828|M.leprae_Br4923 -------------RLPSTARGVVGTSVRQQSSAP-------DRIEAPDAA
Mb3903|M.bovis_AF2122/97 AAAGSSATGG---------------------------------AAPVGAG
Rv3873|M.tuberculosis_H37Rv AAAGSSATGG---------------------------------AAPVGAG
MMAR_5448|M.marinum_M AAAGSSASSG---------------------------------AAPVGAG
Mflv_0768|M.gilvum_PYR-GCK AGAGPGAGVG---------------------------------LAPVGTG
Mvan_0077|M.vanbaalenii_PYR-1 AGAGAGAGAG---------------------------------LAPVGAG
TH_4447|M.thermoresistible__bu AVAG-GAGTG---------------------------------PAPIG-G
MSMEG_0064|M.smegmatis_MC2_155 AGAGSAAAGG---------------------------------LAPVGAG
MAV_2429|M.avium_104 GSKKARARRRRRGTATDRAYRYEYMDLDTDSGPEDGGP----DDGPVASE
MUL_1202|M.ulcerans_Agy99 AAVREEARRRRRKRKTERGYGEEFMDVEVD--PDWGGPL---DDEPVAST
MAB_2230c|M.abscessus_ATCC_199 ASARSRARRKRGARIKDPAP--QFMDMNSPVDPDFSEPATRHTAGVGASG
MLBr_01828|M.leprae_Br4923 ATPQEQARSRWRRRAKVTPFD------------SSGSPNP--KAAPTASD
. * .
Mb3903|M.bovis_AF2122/97 A-------MGQGAQS--GGSTR---PGLVAPAPLAQEREEDDEDDWDEED
Rv3873|M.tuberculosis_H37Rv A-------MGQGAQS--GGSTR---PGLVAPAPLAQEREEDDEDDWDEED
MMAR_5448|M.marinum_M G-------MGAGAGAGAGGSSR---PGMAAPATLTQERDEADEDDWDDED
Mflv_0768|M.gilvum_PYR-GCK GGMGAGGPMGMFGQRGKSGGNK---PGLNAPAPLDHDLGEDEDEEW----
Mvan_0077|M.vanbaalenii_PYR-1 SGMGGGGPMGMLGQRGKSGGNK---PGLNAPAPLEHDLSEDDDDDW----
TH_4447|M.thermoresistible__bu GGMG--APMAAMGQNQKSGGSK---SGLKAPAPLVQDLSEDEGDDW----
MSMEG_0064|M.smegmatis_MC2_155 AGGGAGAPVAHAGQNSKSGGKK---DGLVAPTPLTYDLSEDEDDEW----
MAV_2429|M.avium_104 ASAGQLGFAGAATKSDAARPAG--LATLTRDGSSEGPGVPMMPSTWDRD-
MUL_1202|M.ulcerans_Agy99 QGAGRLGFAGTVHSESAATAAG--LTTLVADEFGGGPKMPMLPGTWDTDS
MAB_2230c|M.abscessus_ATCC_199 RGAGQLGFAGTLPRTTSTTSAAGLIEREAASEMDGTRTVPMLPTSWGTDP
MLBr_01828|M.leprae_Br4923 QGAGTLGLAGTARQASSGPATG--LVTLSNGTFSDSPRAPMLPRTWGADP
. *
Mb3903|M.bovis_AF2122/97 DW------------------------
Rv3873|M.tuberculosis_H37Rv DW------------------------
MMAR_5448|M.marinum_M DW------------------------
Mflv_0768|M.gilvum_PYR-GCK --------------------------
Mvan_0077|M.vanbaalenii_PYR-1 --------------------------
TH_4447|M.thermoresistible__bu --------------------------
MSMEG_0064|M.smegmatis_MC2_155 --------------------------
MAV_2429|M.avium_104 --------------------------
MUL_1202|M.ulcerans_Agy99 DAPSD---------------------
MAB_2230c|M.abscessus_ATCC_199 EPDPDRAPSVPAPDEDWPPGERGAST
MLBr_01828|M.leprae_Br4923 TFCYNAADIGPAGGWDDE--------