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M. thermoresistible (build 8) TH_4410 (-)

annotation: putative cytochrome P450 107B1
coordinates: 657634 - 658842
length: 403

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_4410--100% (403)putative cytochrome P450 107B1
M. thermoresistible (build 8)TH_3048-4e-5333.67% (395) PUTATIVE putative phosphomannomutase/phosphoglucomutase
M. thermoresistible (build 8)TH_2506-5e-5332.43% (404) PUTATIVE cytochrome P450

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2289cyp1246e-5434.45% (389) cytochrome P450 124 CYP124
M. gilvum PYR-GCKMflv_3307-2e-5436.51% (378) cytochrome P450
M. tuberculosis H37RvRv2266cyp1246e-5434.45% (389) cytochrome P450 124 CYP124
M. leprae Br4923MLBr_02088-1e-5533.00% (403) putative cytochrome p450
M. abscessus ATCC 19977MAB_0917c-1e-6335.77% (369) cytochrome P450
M. marinum MMMAR_4833cyp123B12e-5534.41% (404) cytochrome P450 123B1 Cyp123B1
M. avium 104MAV_0358-2e-5433.74% (406) cytochrome P450
M. smegmatis MC2 155MSMEG_3134-4e-6136.62% (396) cytochrome P450 107B1
M. ulcerans Agy99MUL_1282cyp124A12e-5333.93% (389) cytochrome P450 124A1, Cyp124A1
M. vanbaalenii PYR-1Mvan_0317-3e-5634.08% (402) cytochrome P450

CLUSTAL 2.0.9 multiple sequence alignment


TH_4410|M.thermoresistible__bu      ---------------------------------VTVLFDPLDEEQ-LADP
MAB_0917c|M.abscessus_ATCC_199      ---------------------------------MTLSSTELDDLVGAVDR
MLBr_02088|M.leprae_Br4923          MRTCVPTRTCVYAFIEYLSHNRPMGTNPPSLVEAQMLLLRLIDPGTRADP
MAV_0358|M.avium_104                -----------------------MTTAPTESAESQGLLLQLLDPANRADP
MSMEG_3134|M.smegmatis_MC2_155      --------------------------------------MLRLGNSFVQNP
MMAR_4833|M.marinum_M               -------------------------MWQETLMSTVQLRYDPFDPEIQDDP
Mvan_0317|M.vanbaalenii_PYR-1       -------------------------------MVSVQIRYDPFDASILNDP
Mb2289|M.bovis_AF2122/97            -------------MGLNTAIATRVNGTPPPEVPIADIELGSLDFWALDDD
Rv2266|M.tuberculosis_H37Rv         -------------MGLNTAIATRVNGTPPPEVPIADIELGSLDFWALDDD
MUL_1282|M.ulcerans_Agy99           ---------MDLSTNLNTGLLPRVNGTPPPEVPLADIELGSLEFWGRDDD
Mflv_3307|M.gilvum_PYR-GCK          ---------MDG-MSLD-AHPVRRNGIAPPEVPLADIDLGSWEFWGLDDD
                                                                                    : 

TH_4410|M.thermoresistible__bu      IP--TYRALREQDPVQRIPVGG--------GTWVVSRYEDVRRLLRTTAG
MAB_0917c|M.abscessus_ATCC_199      YP--VYKDLRDNQPVLPVEVNGH-------EAYLLTRYADVSRVLKTASA
MLBr_02088|M.leprae_Br4923          FP--VYRALIDYGPMQLPGMP----------LTVFSSFSDCDEALRHPLS
MAV_0358|M.avium_104                YR--LYAQFRERGALQLPEAN----------LAVFLSYRDCDEVLRHPSS
MSMEG_3134|M.smegmatis_MC2_155      HE--VYDRLRRSGPVQRVEMWGGV------PVWLVTRYQEARNLLTDPRI
MMAR_4833|M.marinum_M               YP--VYRQLRDDAPVYHATDTN---------TWVLSRHADVISALLDHHS
Mvan_0317|M.vanbaalenii_PYR-1       YP--TYRLLRDVAPVYRAEESH---------TWVLSRHADVQAAALDHST
Mb2289|M.bovis_AF2122/97            VRDGAFATLRREAPISFWPTIELPGFVAGNGHWALTKYDDVFYASRHPDI
Rv2266|M.tuberculosis_H37Rv         VRDGAFATLRREAPISFWPTIELPGFVAGNGHWALTKYDDVFYASRHPDI
MUL_1282|M.ulcerans_Agy99           FRDGAFATLRREAPISFWPPIELAGLTAGKGHWALTKHDDIHFASRHPEI
Mflv_3307|M.gilvum_PYR-GCK          FRDGAFATLRREAPVSFHRAYITDEDAEVAGHWALTRHDDVFFASRHPEI
                                         :  :    .:                   .  . :          

TH_4410|M.thermoresistible__bu      LMQPPGATVPVELAGG--PAERIYRGLMVLNDPPVHTRLRKLTEKAMTRG
MAB_0917c|M.abscessus_ATCC_199      RVQPRAGEFPAHIGTG--PASEFYRFSLPSMDAPSHTRLRKLAAAAFSPR
MLBr_02088|M.leprae_Br4923          ASDRLKATLAQQAIAAGAEPRPFYASSFMFLDPPDHTRLRKLVSKAFAPK
MAV_0358|M.avium_104                SSDNVNSTVAKRQAAAGTAPVRQGPPGFLFLDPPDHTRLRRLVSKAFAPR
MSMEG_3134|M.smegmatis_MC2_155      GKDGAAASALFPPGTDGSIGTVLG-DNMLFRDPPDHTRLRRFVTSAFTAH
MMAR_4833|M.marinum_M               YS-SVDGVFPTPPGST---FRESLLPMMILMDPPRHDQLRALVSKAFTPR
Mvan_0317|M.vanbaalenii_PYR-1       YS-SVDGIFPTPPGSD---FIGSFLPMMIVMDPPRHDQLRALVSRAFTPR
Mb2289|M.bovis_AF2122/97            FSSYPNITINDQTPEL-----AEYFGSMIVLDDPRHQRLRSIVSRAFTPK
Rv2266|M.tuberculosis_H37Rv         FSSYPNITINDQTPEL-----AEYFGSMIVLDDPRHQRLRSIVSRAFTPK
MUL_1282|M.ulcerans_Agy99           FHSSPNIVIHDQTPEL-----AEYFGSMIVLDDPRHQRLRSIVSRAFTPK
Mflv_3307|M.gilvum_PYR-GCK          FSSALGITVGDQTPEL-----AEYFGSMIAMDDPRHTRLRNIVRSAFTPR
                                                               :   * * * :** :.  *::  

TH_4410|M.thermoresistible__bu      AVEKLRADVERVASEALDAMLEQ---GEADAMTELAFTVPLRVICGMLGI
MAB_0917c|M.abscessus_ATCC_199      AVAAMRSWVEEIIGAGIDRLMDFD--GEFDFVGEFASRVPAEIACRLLHA
MLBr_02088|M.leprae_Br4923          VVQALEGDIAALVDSLLDKGAA---AGQFDVIADLAFPLAVAVICRLLGV
MAV_0358|M.avium_104                VVAALEPDIRSLVDGLLDRAAD---RGELEIVEDFAYPLPVAVICRLLGV
MSMEG_3134|M.smegmatis_MC2_155      AVRRLRPTIAGFADALLDDIAAS-VPGQVDLLQAFAQPLPVQVIGELLGV
MMAR_4833|M.marinum_M               RIAALTSAIEDLADHLTGGLIQE--AGSADFVADFAAVLPAMVIADLLGV
Mvan_0317|M.vanbaalenii_PYR-1       RVAGLQGTITQMAAELFERLDEG--SGSADFVTDFAAILPAAVIADLLGV
Mb2289|M.bovis_AF2122/97            VVARIEAAVRDRAHRLVSSMIANNPDRQADLVSELAGPLPLQIICDMMGI
Rv2266|M.tuberculosis_H37Rv         VVARIEAAVRDRAHRLVSSMIANNPDRQADLVSELAGPLPLQIICDMMGI
MUL_1282|M.ulcerans_Agy99           VVARIEASVRERAHRLVAAMIENHPDGQADLVSELAGPLPLQIICDMMGI
Mflv_3307|M.gilvum_PYR-GCK          VLALIEDSVRQRARRLVEDMVAAHPDGRGELVSELAGPLPLQIICDMMGI
                                     :  :   :                    : :  :*  :.  :   ::  

TH_4410|M.thermoresistible__bu      PEADRAQMLDWTPDFFRIFLP----QANDADGIAACHRACQNFIDYLSEQ
MAB_0917c|M.abscessus_ATCC_199      PMSDAHSVLERMPDLNPILSH----GGITAEQLAAADAAAQFYIDYIGDL
MLBr_02088|M.leprae_Br4923          PYEDAPEFGRVSALLVQSVDPFITITGEPPEATEERLRAGVWLRDYLEQL
MAV_0358|M.avium_104                PLDDEPQFSRASALLAQALDPFSTITGVPAEVASERQQAGTWLRDYFHQL
MSMEG_3134|M.smegmatis_MC2_155      PERDRELFAALVVPIFTSTD------------TTVLRRAQKELTQLLTDM
MMAR_4833|M.marinum_M               PREDRTQFRQWSNALVQSNPT--------HGETGEALAAAAAIYGYFTDF
Mvan_0317|M.vanbaalenii_PYR-1       PATDRDQFRLWSSQLVQVDVN--------HGQTTDALAAAAAIYAYFTDF
Mb2289|M.bovis_AF2122/97            PKADHQRIFHWTNVILGFGDP------DLATDFDEFMQVSADIGAYATAL
Rv2266|M.tuberculosis_H37Rv         PKADHQRIFHWTNVILGFGDP------DLATDFDEFMQVSADIGAYATAL
MUL_1282|M.ulcerans_Agy99           PEEDHEQIFHWTNVILGFGDP------DLTTDFDDFLQVSMAIGGYATAL
Mflv_3307|M.gilvum_PYR-GCK          PPRDHQKIFHWTNVILGFGDP------DIATDFDEFVSVAMGIGAYASEL
                                    *  *   .      :                       .           

TH_4410|M.thermoresistible__bu      IEYRR-RTPADDIFSALVSAEDEGDRLSRDELVATVLSLLTGGFDTTMGM
MAB_0917c|M.abscessus_ATCC_199      VDTLQGKLDSDDAVGALLEAEADGSKMTRTELIITLVGLFIASYHTTMVA
MLBr_02088|M.leprae_Br4923          VKCRR-GTPGEDLISRLIELDESGDQLTEEEIIATCGLLLVAGHETTVNL
MAV_0358|M.avium_104                IEARR-SRPGDDLLSGLIAVEESGDQLTEEEIVSTCNLLLIAGHETTVNL
MSMEG_3134|M.smegmatis_MC2_155      LAEKR-QSPADDVLSSLVHRRDGTDQLSEAELLGTAFLLIVAGYETTVNL
MMAR_4833|M.marinum_M               LADRR-RQPRDDLMSALVCAEIDGKHLSDDELLGFCLLLLIAGHETTSNL
Mvan_0317|M.vanbaalenii_PYR-1       LADRR-KNPREDLMSALANATVDGIGLTDEEVLGFCALLLVAGYETTTNL
Mb2289|M.bovis_AF2122/97            AEDRR-VNHHDDLTSSLVEAEVDGERLSSREIASFFILLVVAGNETTRNA
Rv2266|M.tuberculosis_H37Rv         AEDRR-VNHHDDLTSSLVEAEVDGERLSSREIASFFILLVVAGNETTRNA
MUL_1282|M.ulcerans_Agy99           ADDRR-VNHHGDLTTSLVEAEVDGERLSSSEIAMFFILLVVAGNETTRNT
Mflv_3307|M.gilvum_PYR-GCK          ADDRR-AHPGDDLTTALIEAELDGERLTSAEVASFFILLVVAGNETTRNA
                                        :      *    *         ::  *:      *. .. .**   

TH_4410|M.thermoresistible__bu      IGAGVFGLARQPEQLAALREDPAGLARTAVEEFIRWESPVAVTY-RHFVE
MAB_0917c|M.abscessus_ATCC_199      LTNAVYGFSSHPAQMRTLADNPD-LAPKAWEESLRYRSPVHVVH-RYAGE
MLBr_02088|M.leprae_Br4923          IANAVLAMLRNPSQWKALSSNPQ-RAPLVVEETLRYDPAIHLIG-RVAAK
MAV_0358|M.avium_104                IGNAVLAMLRDPGQWAALGADPG-RAPAIVEETLRYDPPVQLAG-QIALD
MSMEG_3134|M.smegmatis_MC2_155      LANGILALLRNPEQLRAVRADRS-LLPRAVEEALRFESPLNTATVRYTSA
MMAR_4833|M.marinum_M               LANAAVVLADYRDTRRQLAGDES-LLGAAVEELLRYDSPAQGLS-RTLTR
Mvan_0317|M.vanbaalenii_PYR-1       LGNSAVVLAQHRQTRRRLAADRT-LLGPAVEELLRYDSPAQGLS-RTLTR
Mb2289|M.bovis_AF2122/97            ITHGVLALSRYPEQRDRWWSDFDGLAPTAVEEIVRWASPVVYMR-RTLTQ
Rv2266|M.tuberculosis_H37Rv         ITHGVLALSRYPEQRDRWWSDFDGLAPTAVEEIVRWASPVVYMR-RTLTQ
MUL_1282|M.ulcerans_Agy99           ISHGMLALSRYPDERAKWWSDFDGLAATAVEEIVRWASPVVYMR-RTLNQ
Mflv_3307|M.gilvum_PYR-GCK          ISHGVLALSRYPEERDRWWSDYAGLAPTAVEEIVRWASPVAYMR-RTATR
                                    :  .   :            :         ** :*: ..      :    

TH_4410|M.thermoresistible__bu      DVTIADTTIPAGEPIWLLLLSANRDDTRFHDPDGFDVRRKPNQHVAFGGG
MAB_0917c|M.abscessus_ATCC_199      DMVLHDQSIPEGAQLLLGLASANRDERFFDSPDTLDITRGTNRHLAFTGG
MLBr_02088|M.leprae_Br4923          DMTIGQTTLTEGDTMVLLLAAANRDPAVYSRPDEFDPDRPSSRHLAFAVG
MAV_0358|M.avium_104                DMVIGGVEVPAGDVMMLLLAAANRDPAEFDRPDTFDPDRKSLRHLGFGRG
MSMEG_3134|M.smegmatis_MC2_155      PVTVGDVEIPSGELVVIGLLAANHDDEQFPDAHRFDVSRTHNRHLAFGYG
MMAR_4833|M.marinum_M               DVTVHGVRMSAGESVLLLFGSANRDERVFADPDVFDIGRKPEHQVAFGRG
Mvan_0317|M.vanbaalenii_PYR-1       DVTLHDTTMRQGEKVLLLFGSANRDERAFPDPDVFDIERTSEHQVAFGRG
Mb2289|M.bovis_AF2122/97            DIELRGTKMAAGDKVSLWYCSANRDESKFADPWTFDLARNPNPHLGFGGG
Rv2266|M.tuberculosis_H37Rv         DIELRGTKMAAGDKVSLWYCSANRDESKFADPWTFDLARNPNPHLGFGGG
MUL_1282|M.ulcerans_Agy99           DVDLRGTKMAAGDKVTLWYCSANRDEEKFADPWTFDVTRNPNPQVGFGGG
Mflv_3307|M.gilvum_PYR-GCK          DVEVGGQTIAAGDKVTLWYGSANRDETKFDNPWLFDVGRHPNPHVGFGGG
                                     : :    :  *  : :   :**:*   :  .  :*  *    ::.*  *

TH_4410|M.thermoresistible__bu      -RHHCIGSHLARLEGEVVFAEIARRIETIEIT--GDSPRRPNFQFRSFTT
MAB_0917c|M.abscessus_ATCC_199      -GHYCLGAPLSRLEGDYFMRVLPQRLPNIRVT--SDRPDWGTDLSFAFMR
MLBr_02088|M.leprae_Br4923          -SHFCLGAALARLEATVTLSAISARFPQVQLA--GELVYKPNVAMRGMSA
MAV_0358|M.avium_104                -VHYCLGAPLARLEAGVALSAVTARFPRARLD--GEPQYKTNVTLRGLSR
MSMEG_3134|M.smegmatis_MC2_155      -VHHCVGAPLARMEAEIGFDRLLSRFEVMELVDSGPPRYRPSTLMRGVER
MMAR_4833|M.marinum_M               -IHFCLGASLARMEARIALRALLARVPNWEVD-LERAQRLRSGPIRGYLS
Mvan_0317|M.vanbaalenii_PYR-1       -IHFCLGAALARMEARIALNALLDKVPDWEVD-LESARRLRSGPIRGYTS
Mb2289|M.bovis_AF2122/97            GAHFCLGANLARREIRVAFDELRRQMPDVVAT--EEPARLLSQFIHGIKT
Rv2266|M.tuberculosis_H37Rv         GAHFCLGANLARREIRVAFDELRRQMPDVVAT--EEPARLLSQFIHGIKT
MUL_1282|M.ulcerans_Agy99           GAHFCLGANLARREIRVVFDELRRQMPDVVAT--EEPARLLSQFIHGIKR
Mflv_3307|M.gilvum_PYR-GCK          GAHFCLGANLARREITVAFEELHRLVPDIHAT--EEPGRLHSAFIHGIKT
                                      *.*:*: *:* *    :  :   .               .    .   

TH_4410|M.thermoresistible__bu      LPVKMTGRSR------------------------
MAB_0917c|M.abscessus_ATCC_199      SMMVSSGR--------------------------
MLBr_02088|M.leprae_Br4923          LPVQV-----------------------------
MAV_0358|M.avium_104                LVVAV-----------------------------
MSMEG_3134|M.smegmatis_MC2_155      LPVILGYPHDIASTMREWSGSLPSSGEADSSFAH
MMAR_4833|M.marinum_M               LPISWSAN--------------------------
Mvan_0317|M.vanbaalenii_PYR-1       LPITWTTPV-------------------------
Mb2289|M.bovis_AF2122/97            LPVTWS----------------------------
Rv2266|M.tuberculosis_H37Rv         LPVTWS----------------------------
MUL_1282|M.ulcerans_Agy99           LPVAWSR---------------------------
Mflv_3307|M.gilvum_PYR-GCK          LPVAWTPPTR------------------------
                                      :