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M. thermoresistible (build 8) TH_3048 (-)

annotation: putative phosphomannomutase/phosphoglucomutase
coordinates: 1531673 - 1532968
length: 432

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_3048--100% (432)putative phosphomannomutase/phosphoglucomutase
M. thermoresistible (build 8)TH_3377-1e-7940.14% (416) PUTATIVE putative MorD
M. thermoresistible (build 8)TH_2539-1e-5635.40% (404) PUTATIVE cytochrome P450

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2291ccyp1286e-6938.01% (392) cytochrome P450 128
M. gilvum PYR-GCKMflv_0425-5e-5435.05% (388) cytochrome P450
M. tuberculosis H37RvRv2268ccyp1286e-6938.01% (392) cytochrome P450 128
M. leprae Br4923MLBr_02088-3e-5334.28% (388) putative cytochrome p450
M. abscessus ATCC 19977MAB_1216c-7e-5334.00% (400) cytochrome P450
M. marinum MMMAR_4833cyp123B13e-6237.24% (392) cytochrome P450 123B1 Cyp123B1
M. avium 104MAV_0366-2e-5634.75% (400) cytochrome P450 superfamily protein
M. smegmatis MC2 155MSMEG_6312-1e-5535.24% (403) cytochrome P450 107B1
M. ulcerans Agy99MUL_0475cyp123A33e-5133.66% (407) cytochrome P450 123A3 Cyp123A3
M. vanbaalenii PYR-1Mvan_0317-4e-6137.24% (392) cytochrome P450

CLUSTAL 2.0.9 multiple sequence alignment


MAB_1216c|M.abscessus_ATCC_199      --------------------------------------------------
MUL_0475|M.ulcerans_Agy99           --------------------------------------------------
MAV_0366|M.avium_104                --------------------------------------------------
MMAR_4833|M.marinum_M               --------------------------------------------------
Mvan_0317|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_0425|M.gilvum_PYR-GCK          --------------------------------------------------
MLBr_02088|M.leprae_Br4923          -----------------------------------------------MRT
MSMEG_6312|M.smegmatis_MC2_155      --------------------------------------------------
Mb2291c|M.bovis_AF2122/97           MTATQSPPEPAPDRVRLAGCPLAGTPDVGLTAQDATTALGVPTRRRASSG
Rv2268c|M.tuberculosis_H37Rv        MTATQSPPEPAPDRVRLAGCPLAGTPDVGLTAQDATTALGVPTRRRASSG
TH_3048|M.thermoresistible__bu      ---------------------------------MATTQTGNFTANLVKVG
                                                                                      

MAB_1216c|M.abscessus_ATCC_199      -----------------------MTVAETSAVP----------------L
MUL_0475|M.ulcerans_Agy99           -----------------------MSVHVGGPE-----------------L
MAV_0366|M.avium_104                -----------------------MTVANDTAV------------------
MMAR_4833|M.marinum_M               ----------------------MWQETLMSTVQ----------------L
Mvan_0317|M.vanbaalenii_PYR-1       ----------------------------MVSVQ----------------I
Mflv_0425|M.gilvum_PYR-GCK          -----------------------MPADAITLGG----------------A
MLBr_02088|M.leprae_Br4923          CVPTRTCVYAFIEYLSHNRPMGTNPPSLVEAQM----------------L
MSMEG_6312|M.smegmatis_MC2_155      ---------------MHNGWMST-AATAQEAQG----------------L
Mb2291c|M.bovis_AF2122/97           GIPVATSMWRDAQTVRTYGPAVAKALALRVAGKARSRLTGRHCRKFMQLT
Rv2268c|M.tuberculosis_H37Rv        GIPVATSMWRDAQTVRTYGPAVAKALALRVAGKARSRLTGRHCRKFMQLT
TH_3048|M.thermoresistible__bu      --------------VDSLGGVVQDTVIARVKRRNGANDP---------VT
                                                                                      

MAB_1216c|M.abscessus_ATCC_199      VFDPYDYDFHEDPYPYYRRLRDEAPLYRN---DDLKFWALSRHHDVLQGF
MUL_0475|M.ulcerans_Agy99           VLDPYDYDFHEDPYPYYRRLRNEAPLYHN---QELGFWALSRRRDVHQGF
MAV_0366|M.avium_104                YYDPYDIGIITDPYPTYARLREEAPIYYN---ERYDFWALSRHSDVERAL
MMAR_4833|M.marinum_M               RYDPFDPEIQDDPYPVYRQLRDDAPVYHA---TDTNTWVLSRHADVISAL
Mvan_0317|M.vanbaalenii_PYR-1       RYDPFDASILNDPYPTYRLLRDVAPVYRA---EESHTWVLSRHADVQAAA
Mflv_0425|M.gilvum_PYR-GCK          DLADPDTYLAGMPYDAFRTLRREAPVAWHPQVDKPGFWALTGYDEIYAVS
MLBr_02088|M.leprae_Br4923          LLRLIDPGTRADPFPVYRALIDYGPMQLP----GMPLTVFSSFSDCDEAL
MSMEG_6312|M.smegmatis_MC2_155      LLQLLDPATRADPYPIYDRIRRGGPLALP----EANLAVFSSFSDCDDVL
Mb2291c|M.bovis_AF2122/97           DFDPFDPAIAADPYPHYRELLAGERVQYN---PKRDVYILSRYADVREAA
Rv2268c|M.tuberculosis_H37Rv        DFDPFDPAIAADPYPHYRELLAGERVQYN---PKRDVYILSRYADVREAA
TH_3048|M.thermoresistible__bu      RFNPFADAVISNPYPAYRELLAGPPVRYN---PRLGIWIVPRFTDVRAGL
                                                *:  :  :     :             ..   :     

MAB_1216c|M.abscessus_ATCC_199      RNSEALS-NANGVSMDK---ASFGPHAKLVMSFLAMDDPEHLRLRALVSK
MUL_0475|M.ulcerans_Agy99           RNSTTLS-NRDGVSLDP---VSRGPHATKTMSFLAIDDPAHLRLRTLVSK
MAV_0366|M.avium_104                ANWQVFS-NRRSDILEL---IQS-KFDMPGGVMMFQDPPEHTVLRGLMSR
MMAR_4833|M.marinum_M               LDHHSYS-SVDGVFPTP---PGSTFRESLLPMMILMDPPRHDQLRALVSK
Mvan_0317|M.vanbaalenii_PYR-1       LDHSTYS-SVDGIFPTP---PGSDFIGSFLPMMIVMDPPRHDQLRALVSR
Mflv_0425|M.gilvum_PYR-GCK          RDSETWSSQATGVFLDV---PAPEDSYQLALMMLTMDPPRHTALRALVSR
MLBr_02088|M.leprae_Br4923          RHPLSASDRLKATLAQQAIAAGAEPRPFYASSFMFLDPPDHTRLRKLVSK
MSMEG_6312|M.smegmatis_MC2_155      RHPSSCSDRTKSTIFQRQLAAETQPRPQGPASFLFLDPPDHTRLRGLVSK
Mb2291c|M.bovis_AF2122/97           RNHDTLSSARGVTFSRG-----------WLPFLPTSDPPAHTRMRKQLAP
Rv2268c|M.tuberculosis_H37Rv        RNHDTLSSARGVTFSRG-----------WLPFLPTSDPPAHTRMRKQLAP
TH_3048|M.thermoresistible__bu      RDHTKLSSAQSQSRFRV-----------ELPMMITKDPPDHTRLRGLVSR
                                     .    *                         :   * * *  :*  :: 

MAB_1216c|M.abscessus_ATCC_199      GFTPRRIRELEGQVVALARTHLDRALANAS-DRSFDFIAEYAGKLPMDVI
MUL_0475|M.ulcerans_Agy99           GFTPRRIRELEPRVTELAVAHLDTMLDMAGGSQTVDYVAEFAGKLPMDVI
MAV_0366|M.avium_104                VFTPRRMAALEDQIRQYCIRCLDPLVGSSS----FDIIAELASMMPMRVI
MMAR_4833|M.marinum_M               AFTPRRIAALTSAIEDLADHLTGGLIQEAG---SADFVADFAAVLPAMVI
Mvan_0317|M.vanbaalenii_PYR-1       AFTPRRVAGLQGTITQMAAELFERLDEGSG---SADFVTDFAAILPAAVI
Mflv_0425|M.gilvum_PYR-GCK          GFTPRHVARLGARTADMARAIVDDALAHGQ----CEFVDEVAGALPSYVI
MLBr_02088|M.leprae_Br4923          AFAPKVVQALEGDIAALVDSLLDKG-AAAG---QFDVIADLAFPLAVAVI
MSMEG_6312|M.smegmatis_MC2_155      AFAPRVIKRLEPEITALVDQLLDAV-DGP----EFNLIDNLAYPLPVAVI
Mb2291c|M.bovis_AF2122/97           GMARGALETWRPMVDQLARELVGGLLTQTP----ADVVSTVAAPMPMRAI
Rv2268c|M.tuberculosis_H37Rv        GMARGALETWRPMVDQLARELVGGLLTQTP----ADVVSTVAAPMPMRAI
TH_3048|M.thermoresistible__bu      AFTPRALAMWEAVIEQHTDLLLDRMIAMEA----PDGVHDLAQLLPTRLI
                                     ::   :                            : :   *  :.   *

MAB_1216c|M.abscessus_ATCC_199      SELMGVPESDRARIRELADGVMHRED-------GLADVPPEAIQASFDLM
MUL_0475|M.ulcerans_Agy99           SELMGVPVADRDQIRAMADGVMHRED-------GVTDVPASAIEASINLI
MAV_0366|M.avium_104                GMLLGIPESEQVSVRDANDANLRTKP-------GAP--LRVADADSIADG
MMAR_4833|M.marinum_M               ADLLGVPREDRTQFRQWSNALVQSNP-------THG-ETGEALAAAAAIY
Mvan_0317|M.vanbaalenii_PYR-1       ADLLGVPATDRDQFRLWSSQLVQVDV-------NHG-QTTDALAAAAAIY
Mflv_0425|M.gilvum_PYR-GCK          AELLGIPLEDGRRLYTLTDIMNTRPL-------HDP----ELVAAQMQMF
MLBr_02088|M.leprae_Br4923          CRLLGVPYEDAPEFGRVSALLVQSVDPFITITGEPPEATEERLRAGVWLR
MSMEG_6312|M.smegmatis_MC2_155      CRLLGVPIEDEPKFSRASALLAAALDPFLALTGETSDLFDEQMKAGMWLR
Mb2291c|M.bovis_AF2122/97           TSVLGVDGPDEAAFCRLSNQAVR--ITDVA--LSASGLIS--LVQGFAGF
Rv2268c|M.tuberculosis_H37Rv        TSVLGVDGPDEAAFCRLSNQAVR--ITDVA--LSASGLIS--LVQGFAGF
TH_3048|M.thermoresistible__bu      ASMFDIPEADHAKFRSWSEALIDGSFVEVG--RRTFGVVQRMVRATFAMR
                                      ::.:   :   .                                    

MAB_1216c|M.abscessus_ATCC_199      TYYIEMVRERRRR---PTEDLTSALLQAEIDGD-----RLTDEEVLAFLF
MUL_0475|M.ulcerans_Agy99           VYYQQMIAERRKK---PSDDLTSALLAADVDGD-----RLTDEEVLGFMF
MAV_0366|M.avium_104                RIYADYVEWRSKN---PSDDLMTTLLNVEFDDEDGVRRKLTRKEVLHYTQ
MMAR_4833|M.marinum_M               GYFTDFLADRRRQ---PRDDLMSALVCAEIDGK-----HLSDDELLGFCL
Mvan_0317|M.vanbaalenii_PYR-1       AYFTDFLADRRKN---PREDLMSALANATVDGI-----GLTDEEVLGFCA
Mflv_0425|M.gilvum_PYR-GCK          EYAAELAARKRSE---PGDDIATALLHAEVDGR-----RLTDLEFNLFFL
MLBr_02088|M.leprae_Br4923          DYLEQLVKCRRGT---PGEDLISRLIELDESGD-----QLTEEEIIATCG
MSMEG_6312|M.smegmatis_MC2_155      DYLRALIDERRRT---PGEDLMSGLVAVEESGD-----QLTEDEIIATCN
Mb2291c|M.bovis_AF2122/97           RRLRALFTHRRDNGLLRECTVLGKLATHAEQGR------LSDDELFFFAV
Rv2268c|M.tuberculosis_H37Rv        RRLRALFTHRRDNGLLRECTVLGKLATHAEQGR------LSDDELFFFAV
TH_3048|M.thermoresistible__bu      RYLQPLFEERRHH---PGTDLISLMLLSEDGDR------LTDDEIFWGVV
                                             :          :   :      .       *:  *.     

MAB_1216c|M.abscessus_ATCC_199      LMVIAGNETTTKLLANAVYWGHRNPDQLATVHADHDRIPLWVEESLRYDT
MUL_0475|M.ulcerans_Agy99           LMVIAGNETTTKLLANAAFWGHKNTDQLTPIYADLSRVPLWVEETLRYDT
MAV_0366|M.avium_104                VVAGAGNETTGRLIGWLAKVLAEHPDQRREVYRDRSLLTRTVDETLRFEP
MMAR_4833|M.marinum_M               LLLIAGHETTSNLLANAAVVLADYRDTRRQLAGDESLLGAAVEELLRYDS
Mvan_0317|M.vanbaalenii_PYR-1       LLLVAGYETTTNLLGNSAVVLAQHRQTRRRLAADRTLLGPAVEELLRYDS
Mflv_0425|M.gilvum_PYR-GCK          LLINAGGDTTRNLVAAGTLALIEHPDQWRRLAADPSLMPTAVEEMLRWTS
MLBr_02088|M.leprae_Br4923          LLLVAGHETTVNLIANAVLAMLRNPSQWKALSSNPQRAPLVVEETLRYDP
MSMEG_6312|M.smegmatis_MC2_155      LLLIAGHETTVNLIANAALAMLRTPGQWAALAADGSRASAVIEETMRYDP
Mb2291c|M.bovis_AF2122/97           LLLVAGYESTAHMISTLFLTLADYPDQLTLLAQQPDLIPSAIEEHLRFIS
Rv2268c|M.tuberculosis_H37Rv        LLLVAGYESTAHMISTLFLTLADYPDQLTLLAQQPDLIPSAIEEHLRFIS
TH_3048|M.thermoresistible__bu      MLIVAGNETTTNLLGWLLHTFALRPDVYDTVRARPELIPSLIEEQLRFES
                                    ::  ** ::* .::.               :          ::* :*: .

MAB_1216c|M.abscessus_ATCC_199      SSQILARTVAEDITVYDTKIPAGDILLLLPGSANRDDRVFDDADQYRIGR
MUL_0475|M.ulcerans_Agy99           SSQILARTVVGELTLYDTTIPEGDVVLLLPGSAHRDERAFRDPDEYLIGR
MAV_0366|M.avium_104                TGPHVARWMAADFECYGTTVPAGSAMLLLFGAANRDPRRYTDPDTFNIHR
MMAR_4833|M.marinum_M               PAQGLSRTLTRDVTVHGVRMSAGESVLLLFGSANRDERVFADPDVFDIGR
Mvan_0317|M.vanbaalenii_PYR-1       PAQGLSRTLTRDVTLHDTTMRQGEKVLLLFGSANRDERAFPDPDVFDIER
Mflv_0425|M.gilvum_PYR-GCK          PVTVFSRTATRDTDVGGIRLREGERVAMFYPSANRDEKHFADPDRFDIGR
MLBr_02088|M.leprae_Br4923          AIHLIGRVAAKDMTIGQTTLTEGDTMVLLLAAANRDPAVYSRPDEFDPDR
MSMEG_6312|M.smegmatis_MC2_155      PVQLVSRYAGDDLTIGTHTVPKGDTMLLLLAAAHRDPTIVGAPDRFDPDR
Mb2291c|M.bovis_AF2122/97           PIQNICRTTRVDYSVGQAVIPAGSLVLLAWGAANRDPRQYEDPDVFRADR
Rv2268c|M.tuberculosis_H37Rv        PIQNICRTTRVDYSVGQAVIPAGSLVLLAWGAANRDPRQYEDPDVFRADR
TH_3048|M.thermoresistible__bu      PVQGFYRTATSDYPIGDHVIPRQSRVLLLFAAANRDPRHFDDPNTFRPDR
                                    .   . *    :       :   . : :   :*:**      .: :   *

MAB_1216c|M.abscessus_ATCC_199      EIGAKLVSFGSGAHFCLGAHLARMEAKVALTELFTRISGYEIDERNSVRV
MUL_0475|M.ulcerans_Agy99           EIGSKLLSFGSGAHFCLGAHLARMEARVALTELFKRIRGYQVDEGNAVRV
MAV_0366|M.avium_104                DN-ISHITFGKGVHYCLGANLARLEGRVALDELLNRWPEWDIDYDTAQLA
MMAR_4833|M.marinum_M               KP-EHQVAFGRGIHFCLGASLARMEARIALRALLARVPNWEVDLERAQRL
Mvan_0317|M.vanbaalenii_PYR-1       TS-EHQVAFGRGIHFCLGAALARMEARIALNALLDKVPDWEVDLESARRL
Mflv_0425|M.gilvum_PYR-GCK          MPNPHLAFGGGGTHFCLGASLARVEAAAIFRELITRTREIGLVG-PVERV
MLBr_02088|M.leprae_Br4923          PS-SRHLAFAVGSHFCLGAALARLEATVTLSAISARFPQVQLAGELVYKP
MSMEG_6312|M.smegmatis_MC2_155      AQ-IRHLGFGKGAHFCLGAPLARLEATVALPALAARFPEARLSGEPEYKR
Mb2291c|M.bovis_AF2122/97           NP-VGHLAFGSGIHLCPGTQLARMEGQAILREIVANIDRIEVVEPPTWTT
Rv2268c|M.tuberculosis_H37Rv        NP-VGHLAFGSGIHLCPGTQLARMEGQAILREIVANIDRIEVVEPPTWTT
TH_3048|M.thermoresistible__bu      DP-NDHLAFGGGVHFCLGAGLSRLEARHVVAHLTQRVAAVHLAGTPRRLH
                                             . * * * *: *:*:*.   .  :  .     :        

MAB_1216c|M.abscessus_ATCC_199      HSSNVRGFAHLPMTVQLREGR-
MUL_0475|M.ulcerans_Agy99           HSSNVRGFAHLPITVEVA----
MAV_0366|M.avium_104                STSTVRGWERLRIVVP------
MMAR_4833|M.marinum_M               RSGPIRGYLSLPISWSAN----
Mvan_0317|M.vanbaalenii_PYR-1       RSGPIRGYTSLPITWTTPV---
Mflv_0425|M.gilvum_PYR-GCK          RSVLMNGIRSMPAQFTPAVVPA
MLBr_02088|M.leprae_Br4923          N-VAMRGMSALPVQV-------
MSMEG_6312|M.smegmatis_MC2_155      N-LTLRGMSTLSIAV-------
Mb2291c|M.bovis_AF2122/97           N-ANLRGLTRLRVAVTPRVAP-
Rv2268c|M.tuberculosis_H37Rv        N-ANLRGLTRLRVAVTPRVAP-
TH_3048|M.thermoresistible__bu      N-ATMHGWTSLPLRLKPA----
                                        :.*   :