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M. thermoresistible (build 8) TH_4382 (-)

annotation: amino acid permease-associated region
coordinates: 2415444 - 2416883
length: 480

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_4382--100% (480)amino acid permease-associated region
M. thermoresistible (build 8)TH_0471-3e-2823.73% (472) POSSIBLE CATIONIC AMINO ACID TRANSPORT INTEGRAL MEMBRANE
M. thermoresistible (build 8)TH_3126-1e-1228.57% (259) PUTATIVE putative amino acid permease-associated region

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2022c-2e-3027.65% (452) integral membrane protein
M. gilvum PYR-GCKMflv_1611-0.074.32% (479) amino acid permease-associated region
M. tuberculosis H37RvRv1999c-2e-3027.65% (452) integral membrane protein
M. leprae Br4923MLBr_01974-1e-1924.20% (467) putative permease
M. abscessus ATCC 19977MAB_2598-2e-3128.28% (442) hypothetical protein MAB_2598
M. marinum MMMAR_2407rocE_12e-3225.28% (447) cationic amino acid transport integral membrane protein,
M. avium 104MAV_2087-7e-2826.92% (442) amino acid transporter
M. smegmatis MC2 155MSMEG_5848-0.077.20% (478) amino acid permease-associated region
M. ulcerans Agy99MUL_1244rocE7e-2925.93% (455) cationic amino acid transport integral membrane protein RocE
M. vanbaalenii PYR-1Mvan_5147-0.075.32% (474) amino acid permease-associated region

CLUSTAL 2.0.9 multiple sequence alignment


Mb2022c|M.bovis_AF2122/97           --------------------------------------------------
Rv1999c|M.tuberculosis_H37Rv        --------------------------------------------------
MAB_2598|M.abscessus_ATCC_1997      --------------------------------------------------
MAV_2087|M.avium_104                --------------------------------------------------
MUL_1244|M.ulcerans_Agy99           --------------------------------------------------
MMAR_2407|M.marinum_M               --------------------------------------------------
Mflv_1611|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5147|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_5848|M.smegmatis_MC2_155      --------------------------------------------------
TH_4382|M.thermoresistible__bu      --------------------------------------------------
MLBr_01974|M.leprae_Br4923          MFLSADVSCIEIVDINCSELRNDRRIPPQLALFCTNAANKAESAVTSHGQ
                                                                                      

Mb2022c|M.bovis_AF2122/97           --------------------------------------------MRRPLD
Rv1999c|M.tuberculosis_H37Rv        --------------------------------------------MRRPLD
MAB_2598|M.abscessus_ATCC_1997      --------------------------------------------MSSQQ-
MAV_2087|M.avium_104                -------------------------------------------------M
MUL_1244|M.ulcerans_Agy99           ---------------------------MPATSIRLREQMLRRRPAGGAPV
MMAR_2407|M.marinum_M               ---------------------------MAAPTIGLIQQMLRRRPVIGAPV
Mflv_1611|M.gilvum_PYR-GCK          -----------------------------------------MSEHTTGTG
Mvan_5147|M.vanbaalenii_PYR-1       -----------------------------------------MSESVAGPR
MSMEG_5848|M.smegmatis_MC2_155      ---------------------------------------------MTNPE
TH_4382|M.thermoresistible__bu      ---------------------------------------------MSGTR
MLBr_01974|M.leprae_Br4923          LPIMANRRWAPHTRRQSGRATSTCSSLMRFSASESRAHSRFECYTLVRWS
                                                                                      

Mb2022c|M.bovis_AF2122/97           PRDIPDELRRRLGLLDAVVIGLGSMIGAGIFAALAPAAYAAGSGLLLGLA
Rv1999c|M.tuberculosis_H37Rv        PRDIPDELRRRLGLLDAVVIGLGSMIGAGIFAALAPAAYAAGSGLLLGLA
MAB_2598|M.abscessus_ATCC_1997      ----PGALRRELGTFDAVMIGLGSMIGAGIFAALAPAARSAGSALLIGLC
MAV_2087|M.avium_104                APGTADHLRRGIGTFQLTMFGVGSTIGTGIFFVMSQAVPEAGPAVIVSFL
MUL_1244|M.ulcerans_Agy99           AEGAAGSLKRSFGTFELTMFGVGSTVGTGIFFVLAEAVPEAGPAVIVSFI
MMAR_2407|M.marinum_M               AHGASDQLKRSIGTFQLTLFGVGATVGTGIFFVLSEAVPEAGPGVVASFV
Mflv_1611|M.gilvum_PYR-GCK          TTEKQPELRRVMGPGLLLLFVVGDILGTGVYALVGDVAGEVGGAAWLPFL
Mvan_5147|M.vanbaalenii_PYR-1       SPEKQPELKRVMGPGLLLLFVVGDILGTGVYALVGDVAGEVGGAAWLPFL
MSMEG_5848|M.smegmatis_MC2_155      MVEEQPQLRRVMGPGLLLLFVVGDILGTGVYALTGQVAKEVGGAAWLPFL
TH_4382|M.thermoresistible__bu      TEQAQPELRRVLGPGLLLLFIVGDILGTGIYALVGDVAGEVGGAAWLPFL
MLBr_01974|M.leprae_Br4923          IRGQGGRAISKLGFWSVVMLGINSIIGAGIFMTPGEVIKIAGPFAPIAYT
                                               :*     :: :.  :*:*::   . .   .*        

Mb2022c|M.bovis_AF2122/97           VAAVVAYCNAISSARLAARYPASGGTYVYGRMRLG------DFWGYLAGW
Rv1999c|M.tuberculosis_H37Rv        VAAVVAYCNAISSARLAARYPASGGTYVYGRMRLG------DFWGYLAGW
MAB_2598|M.abscessus_ATCC_1997      VAAVIAYCNATSSARLAAVYPASGGTYVYGRERLG------DFWGYLAGW
MAV_2087|M.avium_104                LAGVAAGLAAVCYAELASAVPVSGSSYSYAYTTLG------EVVAMGVAA
MUL_1244|M.ulcerans_Agy99           IAGVAAGLAAICCAELASAVPVSGSSYSYAYATLG------EAVAMGVAS
MMAR_2407|M.marinum_M               IAGIAAGLAAVCYAELASAVPVSGSTYSYAYTTLG------ELVAMGVAA
Mflv_1611|M.gilvum_PYR-GCK          VAFAIATITAFSYLELVTKYPQAAGAALYAHKAFGI-----HFITFLVAF
Mvan_5147|M.vanbaalenii_PYR-1       VAFAIATVTAFSYLELVTKYPQAAGAALYAHKAFGI-----HFITFLVAF
MSMEG_5848|M.smegmatis_MC2_155      VAFLVATVTAFSYLELVTKYPQAAGAALYAHKAFGI-----HFVTFLVAF
TH_4382|M.thermoresistible__bu      IAFLIATVTAFSYLELVTKYPQAAGAALYVHKAFGI-----QFVTFLVAF
MLBr_01974|M.leprae_Br4923          LAGIFAAVLAIVFATAAKYVKTNGSSYAYTTAAFGHRIGIYVGVTHAITA
                                    :*   *   *      .      ..:  *    :*               

Mb2022c|M.bovis_AF2122/97           GFVVGKTASCAAMALTVGFYVWPAQAHAVAVAVVVALTAVNY--------
Rv1999c|M.tuberculosis_H37Rv        GFVVGKTASCAAMALTVGFYVWPAQAHAVAVAVVVALTAVNY--------
MAB_2598|M.abscessus_ATCC_1997      GFVVGKTASCAAMALTIGFYAWPGHAHAVAVASVVALTAINY--------
MAV_2087|M.avium_104                CLLLEYGVATAAVSVNWSGYLNKLLSNVVGFQLPHALSAAPW-DAQPG--
MUL_1244|M.ulcerans_Agy99           CLLLEYGVATAAVAVGLSGYVNKLLHNVFGFQLPQALSEAPW-DERPGEA
MMAR_2407|M.marinum_M               CLLLEYGVSTAAVAVGWSQYVNKLLDNFFGHHLPQALSAAPWGDASPG--
Mflv_1611|M.gilvum_PYR-GCK          VVMCSGITSASTASRAFAANFFTGVGVEDAPKAGVLILALVFMAALAAIN
Mvan_5147|M.vanbaalenii_PYR-1       VVMCSGITSAATASRAFAANFFEGAGID-ASKLGVVVLALLFMAALAAVN
MSMEG_5848|M.smegmatis_MC2_155      IVMCSGITSASTASRFFAANFFTGLHLD-WGKAGVVVLALLFMALIAAVN
TH_4382|M.thermoresistible__bu      IVMCSGITSASTASRFFAANLEVGLGQE-WGRLGVAGVALLFMALLAMVN
MLBr_01974|M.leprae_Br4923          SIAWGVLASSFVSTLLRVAFPEKIWADNDELISVKTLTFLVFIAVLLAIN
                                     .     .:  . :                           :        

Mb2022c|M.bovis_AF2122/97           --------------------AGIQKSAWLTRSIVAVVLVVLTAVVVAAYG
Rv1999c|M.tuberculosis_H37Rv        --------------------AGIQKSAWLTRSIVAVVLVVLTAVVVAAYG
MAB_2598|M.abscessus_ATCC_1997      --------------------VGVQKSAWLTRVIVAIVLSVLAAIVATAAG
MAV_2087|M.avium_104                --YVNLPAVMLIGMCALLLIRGASESAKVNAIMVMVKLGVLVVFGILAFT
MUL_1244|M.ulcerans_Agy99           AGYLNLPAIILIGLCALLLIRGVSESAKVNAIMVLIKLGVLGMFVILALT
MMAR_2407|M.marinum_M               --IINLPAVVLVGLCAVLLIRGASESAKVNTIMVLIKLSVLVMFAVIALT
Mflv_1611|M.gilvum_PYR-GCK          -------------------FRGVGESVKLNVILTIVEITGLVLVILVGLW
Mvan_5147|M.vanbaalenii_PYR-1       -------------------YRGVGESVRLNVVLTIVEITGLVVVVLVGLW
MSMEG_5848|M.smegmatis_MC2_155      -------------------FRGVSESVKLNVFLTFIEITGLALVILVGLW
TH_4382|M.thermoresistible__bu      -------------------LRGVGESVRLNVLLTIVEISGLLLVIFVGLW
MLBr_01974|M.leprae_Br4923          ----------IFGNLVIRWANGISALGKIFALSVFIAGGLWTIITQHVNN
                                                         *      :    . :       .      

Mb2022c|M.bovis_AF2122/97           SGAADPARLDIGVDAHVWG---------MLQAAGLLFFAFAGYARIATLG
Rv1999c|M.tuberculosis_H37Rv        SGAADPARLDIGVDAHVWG---------MLQAAGLLFFAFAGYARIATLG
MAB_2598|M.abscessus_ATCC_1997      SGSVDIAALDL-TGTSWRG---------VLQAAGLLFFAFAGYARIATLG
MAV_2087|M.avium_104                --AFDMHHLDDFAPFGVAG---------VGTAAGTIFFSYIGLDAVSTAG
MUL_1244|M.ulcerans_Agy99           --AYDTNHLKDFAPFGVAG---------VGAAAGTIFFSFIGLDAVSTAG
MMAR_2407|M.marinum_M               --AFDADRFAEFAPFGVAG---------IGAAAGTIFFSYIGLDAVSTAG
Mflv_1611|M.gilvum_PYR-GCK          AFTGG-GEVDFSRVVAFETAEDKNTFLAITAATSLAFFAMVGFEDSVNMA
Mvan_5147|M.vanbaalenii_PYR-1       AFTGG-ADVDFSRITAFETGEDKNTFLAVTAATSLAFFAMVGFEDSVNMA
MSMEG_5848|M.smegmatis_MC2_155      AFTGGSADIDFSRVVAFDTPSDKGVFLAVSTATSLAFFAMVGFEDSVNMA
TH_4382|M.thermoresistible__bu      AFTGGGADVDFTRVVAFETTTDKSVFLAVSAATSLAFFAMVGFEDSVNMA
MLBr_01974|M.leprae_Br4923          YVTSRSAYQPTTYSLLGVTEIGKSTAASMTLATIVALYAFTGFESIANAA
                                      :                         :  *:   :::  *     . .

Mb2022c|M.bovis_AF2122/97           EEVRDPARTIPRAIPLALGITLAVYALVAVAVIAVLGPQRLARAAAPLSE
Rv1999c|M.tuberculosis_H37Rv        EEVRDPARTIPRAIPLALGITLAVYALVAVAVIAVLGPQRLARAAAPLSE
MAB_2598|M.abscessus_ATCC_1997      EEVRDPARTIPRAIPIALGIALVVYVVVALAVLITLGPSRLASSAAPLLD
MAV_2087|M.avium_104                DEVTNPQKTMPRALIAALLTVTGVYVFVALAALGTQPWQDFGGQQEAGLA
MUL_1244|M.ulcerans_Agy99           EEVRNPQQSVPRALIAALFVVTGVYVLVAFAALGTQPWQMFAGQEEAGLA
MMAR_2407|M.marinum_M               DEVKNPQKTMPLAIMAALVTVTTVYVVVTVAALGAQPWRDFEGQQ-AGLA
Mflv_1611|M.gilvum_PYR-GCK          EETKDPVRTFPKILLSGLSIAGVVYILVSIVAVALVPVGKLEESDTPLVE
Mvan_5147|M.vanbaalenii_PYR-1       EETKDPVNTFPKILLSGLSIAGVVYVLISIVAVALVPVGRLEESDTPLVE
MSMEG_5848|M.smegmatis_MC2_155      EETKDPVRIFPKMLLTGLGIAGLVYVVVSIVAVALVPVGVLAGSETPLVE
TH_4382|M.thermoresistible__bu      EETRDPVVIFPRALLTGLGIAGAVYVVVAIVAVALVPVGTLQASDVPLVE
MLBr_01974|M.leprae_Br4923          EEMNTPDRTLPKAIPLTILTVGVIYILALVVAMLLGSDKIVATNHTVKLA
                                    :*   *   .*  :   :  .  :* .  ...:       .         

Mb2022c|M.bovis_AF2122/97           AMRVAGVN--WLIPVVQIGAAVAALGSLLALILGVSRTTLAMARDRHLPR
Rv1999c|M.tuberculosis_H37Rv        AMRVAGVN--WLIPVVQIGAAVAALGSLLALILGVSRTTLAMARDRHLPR
MAB_2598|M.abscessus_ATCC_1997      AVTAAGAG--WMEPVVRIGAVVAATGSLLALILGVSRTTFAMARDRHLPH
MAV_2087|M.avium_104                TILDHVTHGSWASTILAAGAVISIFSVTLVTMYGITRILFAMGRDGLLPP
MUL_1244|M.ulcerans_Agy99           TILDNVTHSAWASTVLAMGAVISIFTVTLVTMYGQTRILFAMGRDGLLPA
MMAR_2407|M.marinum_M               TVLDRVVSGHYWGSVLAAGAVISIFSVTLVVLYGQTRILFAMGRDGLLPP
Mflv_1611|M.gilvum_PYR-GCK          VVRAGAPG-LPIDTILPFMTMFAVSNTALINMLMASRLIYGMARQHVLPP
Mvan_5147|M.vanbaalenii_PYR-1       VVRAGAPG-LPIDAILPFMTMFAVSNTALINMLMASRLIYGMARQHVLPP
MSMEG_5848|M.smegmatis_MC2_155      VVKAGAPG-LPIETILPFISMFAVSNTALINMLMASRLIYGMARQRVLPP
TH_4382|M.thermoresistible__bu      VVKAGAPG-LPIEELLPWISMFAVSNTALINMLMASRLIYGMARQRVLPP
MLBr_01974|M.leprae_Br4923          AAVGNNTF----RTIIVVGALVSMFGINVAASFGAPRLWTALSDGRILPT
                                    .             ::   : .:     :      .*   .:.    ** 

Mb2022c|M.bovis_AF2122/97           WLAAVHPRFKVPFRAELVVGAVVA-------ALAATADIRGAIGFSSFGV
Rv1999c|M.tuberculosis_H37Rv        WLAAVHPRFKVPFRAELVVGAVVA-------ALAATADIRGAIGFSSFGV
MAB_2598|M.abscessus_ATCC_1997      TLATVHPKYGVPYRAEILVGLVVS-------VLAATADLRGAIGFSSFAV
MAV_2087|M.avium_104                RFARVNPRTMTPVNNTVIVAVAAA-------TLAAFIPLQNLADMVSIGT
MUL_1244|M.ulcerans_Agy99           RFAAVHPRFQTPVSNTVVVAIAAA-------VLAALVPLNRLADMVSIGT
MMAR_2407|M.marinum_M               VFAKVRPPNMTPVYNTIIVAVVIC-------ILAGFVPLSYLADVVSIGT
Mflv_1611|M.gilvum_PYR-GCK          ALGLVHPTRRSPWVAIIFTTVIAFGLIAYVSAFASSNAISILGGTTSLLL
Mvan_5147|M.vanbaalenii_PYR-1       VLGTVHPTRRSPWVAILFTTLIAFGLIIYVSTFASSNAIAVLGGTTSLLL
MSMEG_5848|M.smegmatis_MC2_155      VLGSVHPRRLTPWVAILFTTLIAFGLIFYVSAFANSSAIAVLGGTTSLLL
TH_4382|M.thermoresistible__bu      VLGSVHPRRRTPWVAIIFTTLIAFGLIFYVTAFADSTAIAVLGGTTSLLL
MLBr_01974|M.leprae_Br4923          RLSSKN-RFGVPIVAFGITAFLTLAFP-----LSLRFDSLNLTGLAVIAR
                                     :.  .     *     ..             ::         .   :  

Mb2022c|M.bovis_AF2122/97           LVYYAIANASALTLGLDEGR--PRR--------LIPLVGLIGCVVLAFAL
Rv1999c|M.tuberculosis_H37Rv        LVYYAIANASALTLGLDEGR--PRR--------LIPLVGLIGCVVLAFAL
MAB_2598|M.abscessus_ATCC_1997      LVYYAVANASAWTLTPSQGR--PAR--------IIPAVGLVGCVIVSLAL
MAV_2087|M.avium_104                LTAFVVVSVGVIVLRVREPD--LPRGFRVPGYPVTPVLSIMACGYILASL
MUL_1244|M.ulcerans_Agy99           LTAFIVVSVGVIILRVREPA--LPRGFWVPGYPVTPILSILACGYLLYSL
MMAR_2407|M.marinum_M               LVAFIVVSVGVVILRVREPD--LPRGFKVPLYPVTPVLSVLACGYILFSL
Mflv_1611|M.gilvum_PYR-GCK          LSVFAVVNVAVLVLRRDVVR----AGGHFTTPTALPVIGFLASLYLVLPF
Mvan_5147|M.vanbaalenii_PYR-1       LAVFAVVNVAVLALRRDVRE----AGGHFKTPTALPVIGFLASLFLVTPL
MSMEG_5848|M.smegmatis_MC2_155      LAVFAVVNIAVLVLRRDLRE----KGTHFKTPTVLPVIGFIASTYLVLPF
TH_4382|M.thermoresistible__bu      LAVFAMVNVAVLVLRRDESRDPVVARRHFRTPTFLPVVGFVASLYLVTPL
MLBr_01974|M.leprae_Br4923          FIQFIIVPIALFALARSRTTNSVYVKRNVFTDKVLPITAVVVSAGLMVSF
                                    :  : :.  .   *                     *  ..: .  :  .:

Mb2022c|M.bovis_AF2122/97           P---LSSVAAGAAVLGVGVAAYGVRRIITRRARQTDSGDTQRSGHPSAT-
Rv1999c|M.tuberculosis_H37Rv        P---LSSVAAGAAVLGVGVAAYGVRRIITRRARQTDSGDTQRSGHPSAT-
MAB_2598|M.abscessus_ATCC_1997      P---LSSVAAGTGVLAVGVIVYALRRVSGPGRRE----------------
MAV_2087|M.avium_104                H---WYTWIAFSGWVLLALIFYFVWGRHHSALN---DAAVD--PSGQER-
MUL_1244|M.ulcerans_Agy99           H---WYTWIAFGGWVGIALIFYLFWGRHHSRLN---APALHDNPTGEER-
MMAR_2407|M.marinum_M               P---WYTWLAFSIWVSVVLVFYFVWGRHHSALNDGGDGVIGAMPADAGDS
Mflv_1611|M.gilvum_PYR-GCK          SGRPVQQYIVAGGLVVIGVVLFFITQLINKQLGIKSGRITDPTHLGSSPD
Mvan_5147|M.vanbaalenii_PYR-1       SGRPAQQYIVAATLVAIGVVLFFVTQLINRQLGIRDGHITDPTRLGSGTD
MSMEG_5848|M.smegmatis_MC2_155      SGRPAQQYILAGILIAIGIVLFGITTIINRRLGISSKAQIDPTHLTDAP-
TH_4382|M.thermoresistible__bu      SGRPAQQYLLSVVLIVIGVLLFGVTMAINRQLGIPTRAVGDPAKMVLPPD
MLBr_01974|M.leprae_Br4923          DYRSIFLTRGGPNYFSISLIAITFIGIPAVAYLHYYRTSGIK--------
                                                  . : :    .                          

Mb2022c|M.bovis_AF2122/97           --------
Rv1999c|M.tuberculosis_H37Rv        --------
MAB_2598|M.abscessus_ATCC_1997      --------
MAV_2087|M.avium_104                --------
MUL_1244|M.ulcerans_Agy99           --------
MMAR_2407|M.marinum_M               DVLAQRDH
Mflv_1611|M.gilvum_PYR-GCK          --------
Mvan_5147|M.vanbaalenii_PYR-1       --------
MSMEG_5848|M.smegmatis_MC2_155      --------
TH_4382|M.thermoresistible__bu      --------
MLBr_01974|M.leprae_Br4923          --------