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MAAPTIGLIQQMLRRRPVIGAPVAHGASDQLKRSIGTFQLTLFGVGATVGTGIFFVLSEAVPEAGPGVVA SFVIAGIAAGLAAVCYAELASAVPVSGSTYSYAYTTLGELVAMGVAACLLLEYGVSTAAVAVGWSQYVNK LLDNFFGHHLPQALSAAPWGDASPGIINLPAVVLVGLCAVLLIRGASESAKVNTIMVLIKLSVLVMFAVI ALTAFDADRFAEFAPFGVAGIGAAAGTIFFSYIGLDAVSTAGDEVKNPQKTMPLAIMAALVTVTTVYVVV TVAALGAQPWRDFEGQQAGLATVLDRVVSGHYWGSVLAAGAVISIFSVTLVVLYGQTRILFAMGRDGLLP PVFAKVRPPNMTPVYNTIIVAVVICILAGFVPLSYLADVVSIGTLVAFIVVSVGVVILRVREPDLPRGFK VPLYPVTPVLSVLACGYILFSLPWYTWLAFSIWVSVVLVFYFVWGRHHSALNDGGDGVIGAMPADAGDSD VLAQRDH
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_2407 | rocE_1 | - | 100% (497) | cationic amino acid transport integral membrane protein, RocE_1 |
| M. marinum M | MMAR_3621 | rocE | 0.0 | 71.01% (476) | cationic amino acid transport integral membrane protein RocE |
| M. marinum M | MMAR_1290 | - | 3e-76 | 34.11% (472) | cationic amino acid transport integral membrane protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2347c | rocE | 0.0 | 74.68% (470) | cationic amino acid transport integral membrane protein RocE |
| M. gilvum PYR-GCK | Mflv_4722 | - | 1e-84 | 36.60% (470) | amino acid permease-associated region |
| M. tuberculosis H37Rv | Rv2320c | rocE | 0.0 | 74.68% (470) | cationic amino acid transport integral membrane protein RocE |
| M. leprae Br4923 | MLBr_01974 | - | 3e-22 | 23.28% (408) | putative permease |
| M. abscessus ATCC 19977 | MAB_3842 | - | 0.0 | 71.70% (477) | cationic amino acid transport integral membrane protein |
| M. avium 104 | MAV_2087 | - | 0.0 | 75.00% (452) | amino acid transporter |
| M. smegmatis MC2 155 | MSMEG_1412 | - | 0.0 | 68.95% (496) | amino acid permease |
| M. thermoresistible (build 8) | TH_0471 | - | 6e-84 | 36.55% (476) | POSSIBLE CATIONIC AMINO ACID TRANSPORT INTEGRAL MEMBRANE |
| M. ulcerans Agy99 | MUL_1244 | rocE | 0.0 | 70.38% (476) | cationic amino acid transport integral membrane protein RocE |
| M. vanbaalenii PYR-1 | Mvan_1740 | - | 3e-85 | 36.86% (472) | amino acid permease-associated region |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4722|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1740|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_0471|M.thermoresistible__bu --------------------------------------------------
Mb2347c|M.bovis_AF2122/97 --------------------------------------------------
Rv2320c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_1244|M.ulcerans_Agy99 --------------------------------------------------
MAV_2087|M.avium_104 --------------------------------------------------
MAB_3842|M.abscessus_ATCC_1997 --------------------------------------------------
MMAR_2407|M.marinum_M --------------------------------------------------
MSMEG_1412|M.smegmatis_MC2_155 --------------------------------------------------
MLBr_01974|M.leprae_Br4923 MFLSADVSCIEIVDINCSELRNDRRIPPQLALFCTNAANKAESAVTSHGQ
Mflv_4722|M.gilvum_PYR-GCK --------------------------MTQEPVTQAPGRLRLKSVEQSIAD
Mvan_1740|M.vanbaalenii_PYR-1 --------------------------MVQEPGAQTVGRRRTKSVEQSIAD
TH_0471|M.thermoresistible__bu ----------------------------------MTDRLRVKSVEQSIAD
Mb2347c|M.bovis_AF2122/97 --------------------------MPTTSMSLRELMLRRRPVSGAPVA
Rv2320c|M.tuberculosis_H37Rv --------------------------MPTTSMSLRELMLRRRPVSGAPVA
MUL_1244|M.ulcerans_Agy99 --------------------------MPATSIRLREQMLRRRPAGGAPVA
MAV_2087|M.avium_104 ------------------------------------------------MA
MAB_3842|M.abscessus_ATCC_1997 --------------------------MAPSSPSLAQQLLRRRPTSGAPTA
MMAR_2407|M.marinum_M --------------------------MAAPTIGLIQQMLRRRPVIGAPVA
MSMEG_1412|M.smegmatis_MC2_155 --------------------------MSAPPTSMAGQMMRRRPVIGAPVA
MLBr_01974|M.leprae_Br4923 LPIMANRRWAPHTRRQSGRATSTCSSLMRFSASESRAHSRFECYTLVRWS
Mflv_4722|M.gilvum_PYR-GCK TDEPGTKLRKDLNWWDLTVFGVSVVIGAGIFTITASTAANITGPAISLSF
Mvan_1740|M.vanbaalenii_PYR-1 TDEPSTRLRKELNWWDLTVFGVSVVIGAGIFTITASTAANITGPAISLSF
TH_0471|M.thermoresistible__bu TDEPDSRLRKDLSWWDLTVFGVSVVIGAGIFTVTASTAGNITGPAISVSF
Mb2347c|M.bovis_AF2122/97 SG-ASGNLKRSFGTFQLTMFGVGATIGTGIFFVLAQAVP-EAGPGVIVSF
Rv2320c|M.tuberculosis_H37Rv SG-ASGNLKRSFGTFQLTMFGVGATIGTGIFFVLAQAVP-EAGPGVIVSF
MUL_1244|M.ulcerans_Agy99 EG-AAGSLKRSFGTFELTMFGVGSTVGTGIFFVLAEAVP-EAGPAVIVSF
MAV_2087|M.avium_104 PG-TADHLRRGIGTFQLTMFGVGSTIGTGIFFVMSQAVP-EAGPAVIVSF
MAB_3842|M.abscessus_ATCC_1997 HG-AGGHLKQSMGTFQLTMIGVGATVGTGIFFILAESVP-KAGPAVMASF
MMAR_2407|M.marinum_M HG-ASDQLKRSIGTFQLTLFGVGATVGTGIFFVLSEAVP-EAGPGVVASF
MSMEG_1412|M.smegmatis_MC2_155 HG-ASDHLKRSIGTFQLTLFGVGATVGTGIFLVLQEAVP-EAGPAVLVSF
MLBr_01974|M.leprae_Br4923 IRGQGGRAISKLGFWSVVMLGINSIIGAGIFMTPGEVIK-IAGPFAPIAY
:. :.:.::*:. :*:*** . :** ::
Mflv_4722|M.gilvum_PYR-GCK IFAAIACGLAALCYAEFASTVPVAGSAYTFSYATFGEFVAWIIGWDLILE
Mvan_1740|M.vanbaalenii_PYR-1 IIAAIACGLAALCYAEFASTVPVAGSAYTFSYATFGEFVAWIIGWDLILE
TH_0471|M.thermoresistible__bu IIAAIACGLAALCYAEFASTVPVAGSAYTFSYATFGEFVAWIIGWDLILE
Mb2347c|M.bovis_AF2122/97 IIAGIAAGLAAICYAELASAVPISGSAYSYAYTTLGEAVAMVVAACLLLE
Rv2320c|M.tuberculosis_H37Rv IIAGIAAGLAAICYAELASAVPISGSAYSYAYTTLGEAVAMVVAACLLLE
MUL_1244|M.ulcerans_Agy99 IIAGVAAGLAAICCAELASAVPVSGSSYSYAYATLGEAVAMGVASCLLLE
MAV_2087|M.avium_104 LLAGVAAGLAAVCYAELASAVPVSGSSYSYAYTTLGEVVAMGVAACLLLE
MAB_3842|M.abscessus_ATCC_1997 LVAGLAAGLAALCYAELASAVPVSGSSFSYAYTTLGELAAMVVAACLLLE
MMAR_2407|M.marinum_M VIAGIAAGLAAVCYAELASAVPVSGSTYSYAYTTLGELVAMGVAACLLLE
MSMEG_1412|M.smegmatis_MC2_155 VLAGVAAGLSALCYAEMASAVPVSGSTYSYAYTTMGEFVAMGVAACLLLE
MLBr_01974|M.leprae_Br4923 TLAGIFAAVLAIVFATAAKYVKTNGSSYAYTTAAFGHRIGIYVGVTHAIT
.*.: ..: *: * *. * **::::: :::*. . :. :
Mflv_4722|M.gilvum_PYR-GCK FAVAAAVVAKGWSSYLGTVFG-FAGGTAEVAGFDLDWG------------
Mvan_1740|M.vanbaalenii_PYR-1 FAVAAAVVAKGWSSYLGTVFG-FAGGTTEVAGFQLDWG------------
TH_0471|M.thermoresistible__bu FSVAAAVVAKGWSSYLGEVFE-FAGATTRLGPITLDWG------------
Mb2347c|M.bovis_AF2122/97 YGVATAAVAVGWSGYVNKLLSNLFGFQMPHVLSAAPWD-THPG----WVN
Rv2320c|M.tuberculosis_H37Rv YGVATAAVAVGWSGYVNKLLSNLFGFQMPHVLSAAPWD-THPG----WVN
MUL_1244|M.ulcerans_Agy99 YGVATAAVAVGLSGYVNKLLHNVFGFQLPQALSEAPWD-ERPGEAAGYLN
MAV_2087|M.avium_104 YGVATAAVSVNWSGYLNKLLSNVVGFQLPHALSAAPWD-AQPG----YVN
MAB_3842|M.abscessus_ATCC_1997 YGVSAAAVAVGWSQYLDKLLVNLFGWHLPHAISAAPWDSADPAAPHPWLN
MMAR_2407|M.marinum_M YGVSTAAVAVGWSQYVNKLLDNFFGHHLPQALSAAPWGDASPG----IIN
MSMEG_1412|M.smegmatis_MC2_155 YGVSMSATSIGWGGYLNQLLDDVFGFRIPQALTSAPWG-ENPG----IMN
MLBr_01974|M.leprae_Br4923 ASIAWGVLASSFVSTLLRVAFPEKIWADNDELISVKTLT-----------
.:: .. : . : :
Mflv_4722|M.gilvum_PYR-GCK --ALVIIAIVTAILAMGTKLSASVSLAITALKVSVVLLVVIVGAFYIKME
Mvan_1740|M.vanbaalenii_PYR-1 --ALVIIALVTLILVMGTKLSAGVSLAITAVKVSVVLLVVIVGAFYIKAE
TH_0471|M.thermoresistible__bu --ALLIIGFVTVLLATGTKLSANVSLAITVIKVGVVLLVVIVGAFFIKAA
Mb2347c|M.bovis_AF2122/97 LPAVILIGLCALLLIRGASESARVNAIMVLIKLGVLGMFMIIAFSAYSAD
Rv2320c|M.tuberculosis_H37Rv LPAVILIGLCALLLIRGASESARVNAIMVLIKLGVLGMFMIIAFSAYSAD
MUL_1244|M.ulcerans_Agy99 LPAIILIGLCALLLIRGVSESAKVNAIMVLIKLGVLGMFVILALTAYDTN
MAV_2087|M.avium_104 LPAVMLIGMCALLLIRGASESAKVNAIMVMVKLGVLVVFGILAFTAFDMH
MAB_3842|M.abscessus_ATCC_1997 LPAVLLIIMCAILLIRGTSESALVNTVMVLLKLAVLSVFAIIAFTAFHAG
MMAR_2407|M.marinum_M LPAVVLVGLCAVLLIRGASESAKVNTIMVLIKLSVLVMFAVIALTAFDAD
MSMEG_1412|M.smegmatis_MC2_155 LTATLLIVMCGLLLIRGASESALVNTIMVIIKLAVLALFVAVAFTAFTTD
MLBr_01974|M.leprae_Br4923 --FLVFIAVLLAINIFGNLVIRWANGISALGKIFALSVFIAGGLWTIITQ
::: . : * .. . *: .: :. .
Mflv_4722|M.gilvum_PYR-GCK NFSPFIPAPEPGEAGGTGAEQSLFSLMTGAEGSHYGWYGLLAGASIVFFA
Mvan_1740|M.vanbaalenii_PYR-1 NFSPFVPAPEEGGSGGTGTEQSLFSLLTGAEGSHYGWYGVLAGASIVFFA
TH_0471|M.thermoresistible__bu NYTPFIPPAEAGGEAGRSLDQSLFSLITGAEGSSYGWYGLLAGASIVFFA
Mb2347c|M.bovis_AF2122/97 HLKDFVP---------------------------FGVAGIGSAAGTIFFS
Rv2320c|M.tuberculosis_H37Rv HLKDFVP---------------------------FGVAGIGSAAGTIFFS
MUL_1244|M.ulcerans_Agy99 HLKDFAP---------------------------FGVAGVGAAAGTIFFS
MAV_2087|M.avium_104 HLDDFAP---------------------------FGVAGVGTAAGTIFFS
MAB_3842|M.abscessus_ATCC_1997 NFSDFAP---------------------------FGVSGIGAAAGTIFFT
MMAR_2407|M.marinum_M RFAEFAP---------------------------FGVAGIGAAAGTIFFS
MSMEG_1412|M.smegmatis_MC2_155 HFAGFWD---------------------------KGFAGITAAAGSIFFT
MLBr_01974|M.leprae_Br4923 HVNNYVTSR-------SAYQPTTYSLLGVTEIGKSTAASMTLATIVALYA
. : .: .: :::
Mflv_4722|M.gilvum_PYR-GCK FIGFDIVATTAEETKVPQRDVPRGILASLGIVTVLYVAVAIVLSGMVSYK
Mvan_1740|M.vanbaalenii_PYR-1 FIGFDIVATTAEETRNPQRDVPRGILASLAIVTVLYVAVAVVLTGMVSYT
TH_0471|M.thermoresistible__bu FIGFDIIATTAEETKNPQRDVARGIMATLGIVTVLYVAVSLVLTGMVHYT
Mb2347c|M.bovis_AF2122/97 YIGLDAVSTAGDEVKDPQKTMPRALIAALVVVTGVYVLVALAALGTQPWQ
Rv2320c|M.tuberculosis_H37Rv YIGLDAVSTAGDEVKDPQKTMPRALIAALVVVTGVYVLVALAALGTQPWQ
MUL_1244|M.ulcerans_Agy99 FIGLDAVSTAGEEVRNPQQSVPRALIAALFVVTGVYVLVAFAALGTQPWQ
MAV_2087|M.avium_104 YIGLDAVSTAGDEVTNPQKTMPRALIAALLTVTGVYVFVALAALGTQPWQ
MAB_3842|M.abscessus_ATCC_1997 YVGLDTVSTAGEEVKDPQRTMPRALIAALLIVTAFYLVVALAALGAQPWK
MMAR_2407|M.marinum_M YIGLDAVSTAGDEVKNPQKTMPLAIMAALVTVTTVYVVVTVAALGAQPWR
MSMEG_1412|M.smegmatis_MC2_155 FIGLDAVSTAGDEVKNPQKTMPRAILGALVVVASVYILVAFAGLGTQSAD
MLBr_01974|M.leprae_Br4923 FTGFESIANAAEEMNTPDRTLPKAIPLTILTVGVIYILALVVAMLLGSDK
: *:: ::.:.:* *:: :. .: :: * .*: . ..
Mflv_4722|M.gilvum_PYR-GCK DL-RDA-ESPNLATAFS--LNGVDWAAKVISIGALAGLTTVVIVLVLGQT
Mvan_1740|M.vanbaalenii_PYR-1 EL-RDA-ETQNLATAFS--LNGVDWAAKVISIGALAGLTTVVIVLVLGQT
TH_0471|M.thermoresistible__bu EL-RAAGENANLATAFA--ANGIDWAAKVISIGALAGLTTVVIVLVLGQT
Mb2347c|M.bovis_AF2122/97 DF--AEQETAGLAIILDNVTHG-EWASTILAAGAVVSIFTVTLVTMYGQT
Rv2320c|M.tuberculosis_H37Rv DF--AEQETAGLAIILDNVTHG-EWASTILAAGAVVSIFTVTLVTMYGQT
MUL_1244|M.ulcerans_Agy99 MF--AGQEEAGLATILDNVTHS-AWASTVLAMGAVISIFTVTLVTMYGQT
MAV_2087|M.avium_104 DF--GGQQEAGLATILDHVTHG-SWASTILAAGAVISIFSVTLVTMYGIT
MAB_3842|M.abscessus_ATCC_1997 EF--EGQ-SAGLALILDKVTGS-TSASTFLAAGAVISIFSITLVSMYGQT
MMAR_2407|M.marinum_M DF--EGQ-QAGLATVLDRVVSG-HYWGSVLAAGAVISIFSVTLVVLYGQT
MSMEG_1412|M.smegmatis_MC2_155 EFGSEEQSEAGLAVILTNILHGQTWASTILSFGAVISIFSVTLVVMYGQT
MLBr_01974|M.leprae_Br4923 IV--ATNHTVKLAAAVGNNTFR-----TIIVVGALVSMFGINVAASFGAP
. ** . ..: **: .: : :. * .
Mflv_4722|M.gilvum_PYR-GCK RVLFAMSRDGLLPRQLAKTGEH-GTPVRITLLVGAVVAVTATV-FPIDKL
Mvan_1740|M.vanbaalenii_PYR-1 RVLFAMSRDGLLPRQLAKTGEH-GTPVRITLIVGAVVAVTATV-FPIGKL
TH_0471|M.thermoresistible__bu RVLFAMSRDGLLPRPLSKTGPR-GTPVRITVLVGALVAIAASV-FPVGNL
Mb2347c|M.bovis_AF2122/97 RILFAMGRDGLLPARFAKVNPRTMTPVHNTVIVAIFASTLAAF-IPLDSL
Rv2320c|M.tuberculosis_H37Rv RILFAMGRDGLLPARFAKVNPRTMTPVHNTVIVAIFASTLAAF-IPLDSL
MUL_1244|M.ulcerans_Agy99 RILFAMGRDGLLPARFAAVHPRFQTPVSNTVVVAIAAAVLAAL-VPLNRL
MAV_2087|M.avium_104 RILFAMGRDGLLPPRFARVNPRTMTPVNNTVIVAVAAATLAAF-IPLQNL
MAB_3842|M.abscessus_ATCC_1997 RILFAIGRDGLLPSVFAQVNPRTLTPVNNTIIVAVVVGFMAAF-VPLDSL
MMAR_2407|M.marinum_M RILFAMGRDGLLPPVFAKVRPPNMTPVYNTIIVAVVICILAGF-VPLSYL
MSMEG_1412|M.smegmatis_MC2_155 RILFAMGRDGLLPSMFARVNSHTMTPINNTIVVALVTGTLAGF-VPLDYL
MLBr_01974|M.leprae_Br4923 RLWTALSDGRILPTRLSSKNRFGVPIVAFGITAFLTLAFPLSLRFDSLNL
*: *:. . :** :: . : : . . . *
Mflv_4722|M.gilvum_PYR-GCK EEMVNIGTLFAFVLVSAGVIVLRRTRPDLKRGFRTPWVP--VLPILSIIA
Mvan_1740|M.vanbaalenii_PYR-1 EEMVNIGTLFAFVLVSAGVLVLRRTRPDLKRGFRTPWVP--LLPILAIAA
TH_0471|M.thermoresistible__bu EEMVNIGTLFAFALVSAGVIVLRRTRPDLKRGFRVPFVP--WLPLAAIAA
Mb2347c|M.bovis_AF2122/97 ADMVSIGTLTAFSVVAVGVIVLRVREPDLPRGFKVPGYP--VTPVLSVLA
Rv2320c|M.tuberculosis_H37Rv ADMVSIGTLTAFSVVAVGVIVLRVREPDLPRGFKVPGYP--VTPVLSVLA
MUL_1244|M.ulcerans_Agy99 ADMVSIGTLTAFIVVSVGVIILRVREPALPRGFWVPGYP--VTPILSILA
MAV_2087|M.avium_104 ADMVSIGTLTAFVVVSVGVIVLRVREPDLPRGFRVPGYP--VTPVLSIMA
MAB_3842|M.abscessus_ATCC_1997 ANMVSIGTLTAFIVVSIGVIILRVREPELPRAFRVPGYP--VTPVLSVIA
MMAR_2407|M.marinum_M ADVVSIGTLVAFIVVSVGVVILRVREPDLPRGFKVPLYP--VTPVLSVLA
MSMEG_1412|M.smegmatis_MC2_155 WDLVSIGTLVAFIVVSAGVVLLRVREPDLPRSFKVPGYP--VTPVLSIIA
MLBr_01974|M.leprae_Br4923 TGLAVIARFIQFIIVPIALFALARSRTTNSVYVKRNVFTDKVLPITAVVV
:. *. : * :*. .:. * .. . . *: :: .
Mflv_4722|M.gilvum_PYR-GCK CVWLMLNLTGLTWIRFSV---WMAIGVVLYFVYGRRHSLVA---------
Mvan_1740|M.vanbaalenii_PYR-1 CVWLMLNLTGLTWIRFLI---WMAIGVVVYFLYGRRHSLVG---------
TH_0471|M.thermoresistible__bu CLWLMLNLTGLTWVRFLG---WMALGLVLYFFYGRHHSMLG---------
Mb2347c|M.bovis_AF2122/97 CGYILASLHWYTWLAFSG---WVAVAVIFYLMWGRHHSALN---------
Rv2320c|M.tuberculosis_H37Rv CGYILASLHWYTWLAFSG---WVAVAVIFYLMWGRHHSALN---------
MUL_1244|M.ulcerans_Agy99 CGYLLYSLHWYTWIAFGG---WVGIALIFYLFWGRHHSRLN---------
MAV_2087|M.avium_104 CGYILASLHWYTWIAFSG---WVLLALIFYFVWGRHHSALN---------
MAB_3842|M.abscessus_ATCC_1997 CGYILFSLPWITWIAFGA---WVAIVLVFYLVWGRHHSALN---------
MMAR_2407|M.marinum_M CGYILFSLPWYTWLAFSI---WVSVVLVFYFVWGRHHSALNDGGDGVIGA
MSMEG_1412|M.smegmatis_MC2_155 CLFVLYGLPAVTWLWFSV---WVGAVLLFYLLWGRRHSALNDGGDGYIPG
MLBr_01974|M.leprae_Br4923 SAGLMVSFDYRSIFLTRGGPNYFSISLIAITFIGIPAVAYL---------
. :: .: : . :. :: . *
Mflv_4722|M.gilvum_PYR-GCK --RRQRERAGLHTDTP---
Mvan_1740|M.vanbaalenii_PYR-1 --RRMG-------------
TH_0471|M.thermoresistible__bu --RGMTDISARRTG-----
Mb2347c|M.bovis_AF2122/97 --EEVP-------------
Rv2320c|M.tuberculosis_H37Rv --EEVP-------------
MUL_1244|M.ulcerans_Agy99 --APALHDNPTGEER----
MAV_2087|M.avium_104 --DAAVD--PSGQER----
MAB_3842|M.abscessus_ATCC_1997 --DLPSDPAELSEKEPV--
MMAR_2407|M.marinum_M MPADAGDSDVLAQRDH---
MSMEG_1412|M.smegmatis_MC2_155 --AAAGEDDVMTGHPEDRA
MLBr_01974|M.leprae_Br4923 ---HYYRTSGIK-------