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AGKVEGKVAFITGAARGQGRSHAITLAREGADIIAIDVCKQLDGVKLPMSTPDDLAETVRQVEALGRRII ASQVDVRDFDAMQAAVDDGVTQLGRLDIVLANAALASEGTRLNRMDPKTWRDMIDVNLNGAWITARVAIP HIMAGKRGGSIVFTSSIGGLRGAENIGNYIASKHGLHGLMRTMALELGPRNIRVNIVCPSSVATPMLLNE PTYRMFRPDLENPTVEDFKVASRQMHVLPIPYVEPADISNAILFLVSDDARYITGVSLPVDGGALLK*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_1393 | - | - | 100% (278) | carveol dehydrogenase |
| M. avium 104 | MAV_2983 | - | 5e-99 | 59.35% (278) | carveol dehydrogenase |
| M. avium 104 | MAV_0846 | - | 9e-95 | 58.42% (279) | carveol dehydrogenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2771 | - | 4e-62 | 48.20% (278) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. gilvum PYR-GCK | Mflv_2430 | - | 1e-100 | 61.15% (278) | short-chain dehydrogenase/reductase SDR |
| M. tuberculosis H37Rv | Rv2750 | - | 4e-62 | 48.20% (278) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. leprae Br4923 | MLBr_01807 | fabG1 | 4e-24 | 33.66% (202) | 3-oxoacyl- |
| M. abscessus ATCC 19977 | MAB_0072c | - | 1e-74 | 51.27% (275) | putative short chain dehydrogenase/reductase |
| M. marinum M | MMAR_4754 | - | 1e-92 | 58.06% (279) | short-chain type dehydrogenase/reductase |
| M. smegmatis MC2 155 | MSMEG_6031 | - | 1e-95 | 59.14% (279) | carveol dehydrogenase |
| M. thermoresistible (build 8) | TH_3237 | - | 1e-103 | 61.87% (278) | PUTATIVE short-chain dehydrogenase/reductase SDR |
| M. ulcerans Agy99 | MUL_3392 | fabG | 2e-63 | 48.57% (280) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. vanbaalenii PYR-1 | Mvan_4222 | - | 6e-99 | 60.79% (278) | short-chain dehydrogenase/reductase SDR |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2771|M.bovis_AF2122/97 ---MIDRPLEGKVAFITGAARGLGRAHAVRLAADGANIIAVDICEQIAS-
Rv2750|M.tuberculosis_H37Rv ---MIDRPLEGKVAFITGAARGLGRAHAVRLAADGANIIAVDICEQIAS-
MUL_3392|M.ulcerans_Agy99 MSRPLDGPLSGRVAFITGAARGQGRAHALRLARDGADVIAVDLCDQIAS-
Mflv_2430|M.gilvum_PYR-GCK ----MAGRVEGKVAFITGAARGQGRAHAVRLAEEGADIIAVDICKQIDS-
Mvan_4222|M.vanbaalenii_PYR-1 ----MAGRVEGKVAFITGAARGQGRAHAVRLAQEGADIIAVDICKQIDS-
TH_3237|M.thermoresistible__bu ----MAGRLEGKVAFITGAARGQGRAHAVRMAQEGADIIAVDICRQIDS-
MSMEG_6031|M.smegmatis_MC2_155 ----MAGRVEGKVAFITGAARGQGRSHAVRLAEEGADIIAVDVCRRISSN
MMAR_4754|M.marinum_M MTEQLGGRVAGKVAFITGAARGQGRSHAVRLAQEGADIIAVDVCKPIVEN
MAV_1393|M.avium_104 ----MAGKVEGKVAFITGAARGQGRSHAITLAREGADIIAIDVCKQLDG-
MAB_0072c|M.abscessus_ATCC_199 ----MTGRLTGKVALVTGAARGIGRAQAVRFAQEGADIIALDICAPVHT-
MLBr_01807|M.leprae_Br4923 ---------MTDAAAKVSAAPGRGK-----PAFVSRSILVTGGNRGIGLA
.* ..** * *: * . .::. . :
Mb2771|M.bovis_AF2122/97 VPYPLSTADDLAATVELVEDAGGGIVARQGDVRDRASLSVALQAGLDEFG
Rv2750|M.tuberculosis_H37Rv VPYPLSTADDLAATVELVEDAGGGIVARQGDVRDRASLSVALQAGLDEFG
MUL_3392|M.ulcerans_Agy99 VPYPLGTAEELATTVKLVEDTGARIVASQADVRDREALAAALQAGIDELG
Mflv_2430|M.gilvum_PYR-GCK VLIPLSTPEDLAETADLVKNAGGRIHTAEVDVRDYDALKAAVDAGVEEFG
Mvan_4222|M.vanbaalenii_PYR-1 VLIPLSSPEDLAETADLVKNAGGRIHTAEVDVRDFDALKAAVDAGVEEFG
TH_3237|M.thermoresistible__bu VQIPLASPEDLAETADLVKGLNRRIYTAEVDVRDFDALKAAVDTGVEQLG
MSMEG_6031|M.smegmatis_MC2_155 EDIPASTPEDLAETVELVKGLNRRIVAEEVDVRDYDALKAVVDSGVEQLG
MMAR_4754|M.marinum_M TTIPASTPEDLAETADLVKGHNRRIFTAEADVRDYDALKAAVDAGVDELG
MAV_1393|M.avium_104 VKLPMSTPDDLAETVRQVEALGRRIIASQVDVRDFDAMQAAVDDGVTQLG
MAB_0072c|M.abscessus_ATCC_199 TITPPATRADLDKTSELVESAGRRVIPGVVDVRNLRDVQTFTQDAVTEFG
MLBr_01807|M.leprae_Br4923 VARRLVADGHRVAVTHRASVVPDWFFGVECDVTDNDAIGAAFKAVEEHQG
: . . .. . ** : : . . . *
Mb2771|M.bovis_AF2122/97 RLDIVVANAGIAMMQ-----AGDDGWRDVIDVNLTGVFHTVQVAIPTLIE
Rv2750|M.tuberculosis_H37Rv RLDIVVANAGIAMMQ-----AGDDGWRDVIDVNLTGVFHTVQVAIPTLIE
MUL_3392|M.ulcerans_Agy99 QVDIVVANAGIAPMQ-----SGDDGWRDVIDVNLSGAYYTVEVAIPTMIE
Mflv_2430|M.gilvum_PYR-GCK RLDIIVANAGIGNGGQTLDKTDEPDWDDMIGVNLSGVWKTVKAGVPHILA
Mvan_4222|M.vanbaalenii_PYR-1 RLDIIVANAGIGNGGQLLHDTGEPDWDDMIGVNLSGVWKTVKAGVPHILA
TH_3237|M.thermoresistible__bu RLDIIVANAGIGNGGETLDKTSEGDWTDMIDVNLAGVWKTVKAGVPHILA
MSMEG_6031|M.smegmatis_MC2_155 GLDIVVANAGIGNGGATLDKTSEADWDDMIGVNLSGVWKTVKAAVPHLIS
MMAR_4754|M.marinum_M RLDIIVANAGIGNGGATLDKTSEHDWQEMIDVNLSGVWKSVKAAVPHLIA
MAV_1393|M.avium_104 RLDIVLANAALASEGTRLNRMDPKTWRDMIDVNLNGAWITARVAIPHIMA
MAB_0072c|M.abscessus_ATCC_199 GLDIVCATAGITSRRMLLDMP-ESDWQTMLDVNLTGVWHTTRAATPHLIA
MLBr_01807|M.leprae_Br4923 PVEVLVANAGITSDMLIMR-MSEEQFQKVIDVNLTGVFRVAKLASRNMIK
:::: *.*.: : ::.*** *.: .. . ::
Mb2771|M.bovis_AF2122/97 QGTGGSIVLISSAAGLVGIGSSDPGSLGYAAAKHGVVGLMRAYANHLAPQ
Rv2750|M.tuberculosis_H37Rv QGTGGSIVLISSAAGLVGIGSSDPGSLGYAAAKHGVVGLMRAYANHLAPQ
MUL_3392|M.ulcerans_Agy99 QGRGGSIVLISSAAGLVGISSADAGAIGYVASKHALVGLMRVYANLLAPH
Mflv_2430|M.gilvum_PYR-GCK GGNGGSIILTSSVGGLKAYPHTG----HYVAAKHGVVGLMRTFAVELGAQ
Mvan_4222|M.vanbaalenii_PYR-1 GGNGGSIILTSSVGGLKAYPHTG----HYVAAKHGVVGLMRTFAVELGAQ
TH_3237|M.thermoresistible__bu GGRGGSIILTSSVGGLKAYPHTG----HYVAAKHGVVGLMRTFAVELGQH
MSMEG_6031|M.smegmatis_MC2_155 GGNGGSIILTSSVGGLKAYPHTG----HYIAAKHGVVGLMRTFAVELGQH
MMAR_4754|M.marinum_M GGNGGSIVLTSSVGGMKAYPHCG----NYVAAKHGVVGLMRSFAVELGQH
MAV_1393|M.avium_104 GKRGGSIVFTSSIGGLRGAENIG----NYIASKHGLHGLMRTMALELGPR
MAB_0072c|M.abscessus_ATCC_199 RG-GGAMVLVSSIAGLRGLVGVS----HYVAAKHGVVGLMRSLAIELAPH
MLBr_01807|M.leprae_Br4923 QRFGRYIFMG-SVVGLSGVPGQA----NYAASKSGLIGMARSLARELGSR
* :.: * *: . * *:* .: *: * * *. :
Mb2771|M.bovis_AF2122/97 NIRVNSVHPCGVDTPMINNEFFQQWLT-------TADMDAPHNLGNALPV
Rv2750|M.tuberculosis_H37Rv NIRVNSVHPCGVDTPMINNEFFQQWLT-------TADMDAPHNLGNALPV
MUL_3392|M.ulcerans_Agy99 SIRVNSLHPSGVDPPMINNEFIRHWLAD-----LVAETGSGPGAGNALPV
Mflv_2430|M.gilvum_PYR-GCK NIRVNSVHPTNVNTPLFMNEPTMKLFRPDLENPGPDDMKVVGQLMHTLPI
Mvan_4222|M.vanbaalenii_PYR-1 NVRVNSVHPTNVNTPLFMNEPTMKLFRPDLENPGPEDMKVVGQLMHTLPI
TH_3237|M.thermoresistible__bu NIRVNSVHPTNVNTPLFMNEPTMKLFRPDLENPGPEDLKVVAQMMHTLPI
MSMEG_6031|M.smegmatis_MC2_155 SIRVNSVHPTNVNTPLFMNEGTMKLFRPDLENPGPDDMAVVAQMMHVLPV
MMAR_4754|M.marinum_M MIRVNSVHPTHVRTPMLHNEGTFKMFRPDLENPGPDDMAPICQLFHTLPI
MAV_1393|M.avium_104 NIRVNIVCPSSVATPMLLNEPTYRMFRPDLENPTVEDFKVASRQMHVLPI
MAB_0072c|M.abscessus_ATCC_199 KIRVNTVHPTNVDTPMIQNEFVRTLFRPDLEQPTREDFAAAAKTMNLLDL
MLBr_01807|M.leprae_Br4923 SITANVVAPGFIDTEMTR----------------AMDSKYQEAALQAIPL
: .* : * : . : : : : :
Mb2771|M.bovis_AF2122/97 ELV-QPTDIANAVAWLASEEARYVTGVTLPVDAGFVNKR
Rv2750|M.tuberculosis_H37Rv ELV-QPTDIANAVAWLASEEARYVTGVTLPVDAGFVNKR
MUL_3392|M.ulcerans_Agy99 QIL-QADDIAGALAWLVSDEARYITGVALPVDAGCVNKR
Mflv_2430|M.gilvum_PYR-GCK GWV-EPEDIANAVLFLASDEARFITGVTLPVDGGSCLK-
Mvan_4222|M.vanbaalenii_PYR-1 GWV-EPEDIANAVLFLASDEARFITGVTLPVDGGSCLK-
TH_3237|M.thermoresistible__bu GWV-EPEDIANAVLFLASDEARYITGVTLPVDGGSCLK-
MSMEG_6031|M.smegmatis_MC2_155 GWV-EPRDISNAVLFLASDEARYVTGLPMTVDAGSMLK-
MMAR_4754|M.marinum_M PWV-EAEDISNAVLFLASDESRYITGVTLPVDAGGCLK-
MAV_1393|M.avium_104 PYV-EPADISNAILFLVSDDARYITGVSLPVDGGALLK-
MAB_0072c|M.abscessus_ATCC_199 PWV-EPLDIANASLFLASDEARYITSVSLPVDAGSTQR-
MLBr_01807|M.leprae_Br4923 GRIGAVEEIAGAVSFLASEDAGYISGAVIPVDGGLGMGH
: :*:.* :*.*::: :::. :.**.*