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aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_3917 | - | - | 100% (381) | putative RNA polymerase, sigma-24 subunit, ECF subfamily |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1221 | sigI | 2e-11 | 32.11% (190) | RNA polymerase sigma factor SigI |
| M. gilvum PYR-GCK | Mflv_1191 | - | 4e-06 | 31.01% (129) | ECF subfamily RNA polymerase sigma-24 factor |
| M. tuberculosis H37Rv | Rv1189 | sigI | 2e-11 | 32.11% (190) | RNA polymerase sigma factor SigI |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4459c | - | 5e-70 | 46.17% (392) | ECF subfamily RNA polymerase sigma factor |
| M. marinum M | MMAR_0975 | - | 4e-56 | 42.20% (391) | RNA polymerase sigma factor |
| M. avium 104 | MAV_4519 | - | 2e-57 | 42.25% (400) | RNA polymerase ECF-subfamily protein sigma factor |
| M. smegmatis MC2 155 | MSMEG_0405 | - | 1e-161 | 76.32% (380) | extra cytoplasmic sigma factor |
| M. ulcerans Agy99 | MUL_3630 | - | 3e-05 | 30.43% (184) | alternative RNA polymerase sigma factor SigJ- like |
| M. vanbaalenii PYR-1 | Mvan_2612 | - | 1e-164 | 77.84% (379) | RNA polymerase ECF-subfamily sigma factor |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_0405|M.smegmatis_MC2_155 -----MDPAALRDLIPGVLAALVRRGVDFATAEDAVQEALIKALETWSTG
Mvan_2612|M.vanbaalenii_PYR-1 -MSTAVDETALRDLIPGVLAALVHRGADFATAEDAVQEALIRAVQTWPR-
TH_3917|M.thermoresistible__bu ----VIDGRRLRELIPGVLGTLVRRGADFASAEDAVQEALVRALTTWAG-
MMAR_0975|M.marinum_M -MAN--LDGVFRREWGSAVAALARWSGDLTIAEDAVQEACAEALRAWPRD
MAV_4519|M.avium_104 -MAD--LDGVFRREWGPAVAALARWSGDLTVAEDAVQEACAEALRAWPRD
MAB_4459c|M.abscessus_ATCC_199 -MAHDEISRIFRAEYGRTVATLIRYFGSIDLAEDAVQEAFEVAIARWPED
Mb1221|M.bovis_AF2122/97 MSQHDPVSAAWRAHRAYLVDLAFRMVGDIGVAEDMVQEAFSRLLRAPVG-
Rv1189|M.tuberculosis_H37Rv MSQHDPVSAAWRAHRAYLVDLAFRMVGDIGVAEDMVQEAFSRLLRAPVG-
Mflv_1191|M.gilvum_PYR-GCK -MITP---SVFEATRPQLTAMAFRMLGSIHDAEDAVQSAWIKASITAT--
MUL_3630|M.ulcerans_Agy99 -MTDPALLARFQAARPRLGALAYRMLGSLADAEDVVQEAWLRLNATTDRP
. : .: *** **.*
MSMEG_0405|M.smegmatis_MC2_155 ---RAPDDPKAWLITTAWRRFIDVARAEAARRSRELR---------TAVE
Mvan_2612|M.vanbaalenii_PYR-1 ---RHPDDPRGWLITTAWRRFVDLVRADAARRDRELK---------SFDE
TH_3917|M.thermoresistible__bu ---KPPRDPKGWLITTAWRCFVDATRSDAARRRREEL---------IATR
MMAR_0975|M.marinum_M ---GVPDSPGGWLVTVARNRARDRLRRESARPAKELAYVVNDIGAIRART
MAV_4519|M.avium_104 ---GMPANPGGWLVTVARNRARDRLRRESARPGKELAAVLDDI---RART
MAB_4459c|M.abscessus_ATCC_199 ---GIPPNPGAWITTTARNRGIDKLRRDRRR--DELSREAGAFA--EPQQ
Mb1221|M.bovis_AF2122/97 ----DIDDERGWLIVVTSRLCLDHIKSASTRRERPQDIAAWHDGDASVSS
Rv1189|M.tuberculosis_H37Rv ----DIDDERGWLIVVTSRLCLDHIKSASTRRERPQDIAAWHDGDASVSS
Mflv_1191|M.gilvum_PYR-GCK ---DDLRNPAAYLTTVLTRECVDQLRMRQRRREEPLAADMIP--ADTVAA
MUL_3630|M.ulcerans_Agy99 EGAQELVNLDAWLTTVVARLCLNLLRDRRGRGREELVGQLPDPIVDGVAA
. .:: .. . : : *
MSMEG_0405|M.smegmatis_MC2_155 DPQGPTVPVDDTLQLYFLCAHPSLSPASAVALTLRAVGGLTTRQIARAYL
Mvan_2612|M.vanbaalenii_PYR-1 PPPGPAEHADDTLYLYFLCAHPSLTPSSAVALTLRAVGGLTTRQIAQAYL
TH_3917|M.thermoresistible__bu PPPGPVPAVDDTLALYFLCAHPRLSPASAVALTLRAVGGLTTRQIAQAYL
MMAR_0975|M.marinum_M EHSDPHPVRDDELRMMFTCAHPALDRQSQLALTLRLVSGLTVTEIARALL
MAV_4519|M.avium_104 DAADPHPVRDDELRMMFTCAHPALDRPSQLALTLRLVSGLTVAEIARALL
MAB_4459c|M.abscessus_ATCC_199 EPEDVGPVRDDRLRLIFTCCHPALSQEAQVALTLRLLGGLTTPEIAGAYL
Mb1221|M.bovis_AF2122/97 VDPADRVTLDDEVRLALLIMLERLGPAERVVFVLHEIFGLPYQQIATTIG
Rv1189|M.tuberculosis_H37Rv VDPADRVTLDDEVRLALLIMLERLGPAERVVFVLHEIFGLPYQQIATTIG
Mflv_1191|M.gilvum_PYR-GCK ---DEHYLRRESISRALMVVLDRLTPSQRVAYVLHDVFAVPFQEIAETLG
MUL_3630|M.ulcerans_Agy99 FDPEHHAMLADAVGLALFVVLDTLAPAERLAFVLHDVFAVPFDQIAPILE
: : : * :. .*: : .:. :**
MSMEG_0405|M.smegmatis_MC2_155 VPESTMAQRISRAKRTVSEVRLNR--------LGNLGTVLRVLYLVFNEG
Mvan_2612|M.vanbaalenii_PYR-1 VPESTMAQRISRAKRTVSDVRLDR--------PGDVRTVLRVLYLVFNEG
TH_3917|M.thermoresistible__bu VPESTMAQRISRAKHTIADVQPGR--------PGDLRTVLRVLYLVFNEG
MMAR_0975|M.marinum_M QTDAAIGQRITRAKNKIRHANIPLRVPPAELLPERTPHVLGCIYSVFTEG
MAV_4519|M.avium_104 QSEAAISQRITRAKNKVRHANIPLRVPPAELLGERTPHVLGCVYSVFTEG
MAB_4459c|M.abscessus_ATCC_199 VSESTMAARITRAKKKIAAAGIPYRIPAAHDLPDRLSSVLSVLYLIYNEG
Mb1221|M.bovis_AF2122/97 SQASTCRQLAHRARRKINES------------------------------
Rv1189|M.tuberculosis_H37Rv SQASTCRQLAHRARRKINES------------------------------
Mflv_1191|M.gilvum_PYR-GCK TSPASAKKHASRARERIHRT------------------------------
MUL_3630|M.ulcerans_Agy99 RTPEATRKLASRARRRIERA------------------------------
: **:. :
MSMEG_0405|M.smegmatis_MC2_155 YTG-------DVDLSAEAIRLARQLAAATD-APEVAGLLALFLLHDARRP
Mvan_2612|M.vanbaalenii_PYR-1 YSG-------DVDLAAEAIRLARQLAAVVD-DPEVSGLLALFLLHHARRP
TH_3917|M.thermoresistible__bu YTG-------EVDLAEEAIRLARRLVAVTD-DPEVAGLLALFLLHHARRP
MMAR_0975|M.marinum_M YWATGGPSAIRDELCDEGVRLAQELCALMPQEPETHALAALVLLHDSRRA
MAV_4519|M.avium_104 YWSTAGPSAIRDDLCDEGIRLGAELCALLPHEREAHALSALMLLHDSRRA
MAB_4459c|M.abscessus_ATCC_199 YAASSGARLTRTDLSAEAIRLSRLLADLMPDEPEALGLLALVLLTEARRP
Mb1221|M.bovis_AF2122/97 -----------RIAASVEPAQHRVVTRAFIEACSNGDLDTLLEVLDPGVA
Rv1189|M.tuberculosis_H37Rv -----------RIAASVEPAQHRVVTRAFIEACSNGDLDTLLEVLDPGVA
Mflv_1191|M.gilvum_PYR-GCK -----------VQIP-AAATIDSAVVEAFLAAAAGGDTATMVALMADDCV
MUL_3630|M.ulcerans_Agy99 -----------EPFPDRDLCAQREVVDAFFAAGRSGNFERLVSVLHPDVV
: :. :
MSMEG_0405|M.smegmatis_MC2_155 ARTRADGTLVPLAEQDRTLWRHDLITEGVAVLQAALAADRLGEYQAQAAI
Mvan_2612|M.vanbaalenii_PYR-1 ARMRGDGSLVPLAEQNRGLWRTDLIAEGVTVLQAALARDRLGEYQAQAAI
TH_3917|M.thermoresistible__bu ARTRADGSLVPLAEQDRSVWRRDLIAEGVGILQAALARDRLGEYQAQAAI
MMAR_0975|M.marinum_M TRVDEAGALVPLDEQDRSRWDHGRIARGLDRLRRASGS--RGPYLPQAVI
MAV_4519|M.avium_104 TRVDAHGVPVPLEEQDRTRWDRRRITAGLDRLRYAEGS--SGAYLPQAVI
MAB_4459c|M.abscessus_ATCC_199 ARTGDDGALVLLADQDRTRWNRQMITEGHQLVRRCLRRNVPGPYQIQAAI
Mb1221|M.bovis_AF2122/97 GEID----------------------------------------------
Rv1189|M.tuberculosis_H37Rv GEID----------------------------------------------
Mflv_1191|M.gilvum_PYR-GCK RVADP-------------------------------------------TL
MUL_3630|M.ulcerans_Agy99 LRGD---------------------------------------------F
MSMEG_0405|M.smegmatis_MC2_155 AALHADARTADETDWVQIVEWYDELVALTDSPVARLNRAVAVGEADGPRA
Mvan_2612|M.vanbaalenii_PYR-1 AALHADAQTAEETDWVQIVEWYDELVRLTDSPVVRLNRAVAVGEADGPRA
TH_3917|M.thermoresistible__bu AALHADAQRVEDTDWVQIVEWYDELVALTGSPVVRLNRAVAVGAAAGPRA
MMAR_0975|M.marinum_M AALHASAPSWEHTDWTTICAAYDRLLQLTDSPVVLANRALAVGFRDGPDA
MAV_4519|M.avium_104 AALHATAPSWEETDWVTICAAYDRLWQLTRSPVVAANRALAIGLRDGPDA
MAB_4459c|M.abscessus_ATCC_199 NAVHDDAPSAAGTDWRQIVTLYDQLMRFTPTTVVALNRAVAVAERDGAQA
Mb1221|M.bovis_AF2122/97 -ARKGVVVVGADRVGPTILRHWSHPATVLVAQPVCGQPAVLAFVNRALAG
Rv1189|M.tuberculosis_H37Rv -ARKGVVVVGADRVGPTILRHWSHPATVLVAQPVCGQPAVLAFVNRALAG
Mflv_1191|M.gilvum_PYR-GCK LPAHTPAVVIGDSAVADETSLFIDRIRVSAPMLVDGRTVHVIAPGGHELA
MUL_3630|M.ulcerans_Agy99 GPNTPRFRAQGAATVAKLARSYAGPERTVLNTLVNGAAGAVISISEQASA
. : . .
MSMEG_0405|M.smegmatis_MC2_155 GLAALAELD--PALPRH---TASAAYLHERAGDIARAAQLYVEAADQAHT
Mvan_2612|M.vanbaalenii_PYR-1 GLTALANLD--PTLPRY---TASKAYLCEKAGDTEAAAALYAEAAAQAYN
TH_3917|M.thermoresistible__bu GLAALAELD--PELPRH---TAAAAYLHEQAGDIATAADLYAEAAAKADN
MMAR_0975|M.marinum_M GLAALEEVAHDPRLSHSNLVASARADLLRRAGRGADALRWYRVALDSNGS
MAV_4519|M.avium_104 GLAALEEVD-EPKLERSNLIATLRADLLRRAGRPAEALPWYRIASQSNGS
MAB_4459c|M.abscessus_ATCC_199 GLDAMEPLR--ADLDRYYPLHAARADLLTRLHRDSEAADAYRKALELTEN
Mb1221|M.bovis_AF2122/97 VLALSIEAG-----------KITKIHVLVQPSTLDPLRAELGGG------
Rv1189|M.tuberculosis_H37Rv VLALSIEAG-----------KITKIHVLVQPSTLDPLRAELGGG------
Mflv_1191|M.gilvum_PYR-GCK VIDITVTDG-----------RIARIEITRTHP-------SGRR-------
MUL_3630|M.ulcerans_Agy99 VMRFLVRNG-----------RIAAIDVLADPQRIATLDISGLSGPGG---
: :
MSMEG_0405|M.smegmatis_MC2_155 VPERNHLLLKAATLHQRLGSPGDAKRLPG---
Mvan_2612|M.vanbaalenii_PYR-1 VAERNHLTLRAATLRQALPHDSD---------
TH_3917|M.thermoresistible__bu LAERNHLTLRAATLRRRI--------------
MMAR_0975|M.marinum_M EPSRGFLQRRIAECQG----------------
MAV_4519|M.avium_104 EPGREFLRRRIAECTSAAESATGDAFPENGRR
MAB_4459c|M.abscessus_ATCC_199 EVFRRYLGDRLARLEPGA--------------
Mb1221|M.bovis_AF2122/97 --------------------------------
Rv1189|M.tuberculosis_H37Rv --------------------------------
Mflv_1191|M.gilvum_PYR-GCK --------------------------------
MUL_3630|M.ulcerans_Agy99 --------------------------------