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MADLDGVFRREWGPAVAALARWSGDLTVAEDAVQEACAEALRAWPRDGMPANPGGWLVTVARNRARDRLR RESARPGKELAAVLDDIRARTDAADPHPVRDDELRMMFTCAHPALDRPSQLALTLRLVSGLTVAEIARAL LQSEAAISQRITRAKNKVRHANIPLRVPPAELLGERTPHVLGCVYSVFTEGYWSTAGPSAIRDDLCDEGI RLGAELCALLPHEREAHALSALMLLHDSRRATRVDAHGVPVPLEEQDRTRWDRRRITAGLDRLRYAEGSS GAYLPQAVIAALHATAPSWEETDWVTICAAYDRLWQLTRSPVVAANRALAIGLRDGPDAGLAALEEVDEP KLERSNLIATLRADLLRRAGRPAEALPWYRIASQSNGSEPGREFLRRRIAECTSAAESATGDAFPENGRR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_4519 | - | - | 100% (420) | RNA polymerase ECF-subfamily protein sigma factor |
| M. avium 104 | MAV_4998 | - | 8e-06 | 27.98% (168) | RNA polymerase factor sigma-70 |
| M. avium 104 | MAV_2018 | - | 1e-05 | 29.94% (167) | RNA polymerase ECF-subfamily protein sigma factor |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1221 | sigI | 7e-09 | 29.22% (154) | RNA polymerase sigma factor SigI |
| M. gilvum PYR-GCK | Mflv_1191 | - | 3e-08 | 32.68% (153) | ECF subfamily RNA polymerase sigma-24 factor |
| M. tuberculosis H37Rv | Rv1189 | sigI | 7e-09 | 29.22% (154) | RNA polymerase sigma factor SigI |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3888 | - | 0.0 | 78.91% (403) | putative RNA polymerase sigma-70 factor |
| M. marinum M | MMAR_0975 | - | 0.0 | 81.28% (406) | RNA polymerase sigma factor |
| M. smegmatis MC2 155 | MSMEG_1348 | - | 1e-172 | 73.96% (407) | RNA polymerase ECF-subfamily protein sigma factor |
| M. thermoresistible (build 8) | TH_3917 | - | 2e-57 | 42.25% (400) | PUTATIVE putative RNA polymerase, sigma-24 subunit, ECF |
| M. ulcerans Agy99 | MUL_1400 | sigK | 3e-08 | 28.67% (143) | RNA polymerase sigma factor SigK |
| M. vanbaalenii PYR-1 | Mvan_3355 | - | 1e-180 | 77.97% (404) | RNA polymerase ECF-subfamily sigma factor |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1221|M.bovis_AF2122/97 -------------------MSQHDPVSAAWRAHRAYLVDLAFRMVGDIGV
Rv1189|M.tuberculosis_H37Rv -------------------MSQHDPVSAAWRAHRAYLVDLAFRMVGDIGV
MAV_4519|M.avium_104 -------------------MADLD--GVFRREWGP-AVAALARWSGDLTV
MMAR_0975|M.marinum_M -------------------MANLD--GVFRREWGS-AVAALARWSGDLTI
MAB_3888|M.abscessus_ATCC_1997 -------------------MIELE--GVFRREWGP-TVAAIARWSGDLTV
Mvan_3355|M.vanbaalenii_PYR-1 -------------------MQSLD--GVFRREWGR-TVAAIARWCGDLTV
MSMEG_1348|M.smegmatis_MC2_155 -------------------MAELD--SVFRREWGP-TVATIARWSGDLAL
TH_3917|M.thermoresistible__bu ---------------------VID--GRRLRELIPGVLGTLVRRGADFAS
Mflv_1191|M.gilvum_PYR-GCK -------------------MITPS----VFEATRPQLTAMAFRMLGSIHD
MUL_1400|M.ulcerans_Agy99 MTGPPGRSDDLNALLRQIARGERDAFAMFYDHTCTRVYGLVARVLRDAGY
. * .
Mb1221|M.bovis_AF2122/97 AEDMVQEAFSRLLRAPVG-DIDDE--RGWLIVVTSRLCLDHIKSASTRRE
Rv1189|M.tuberculosis_H37Rv AEDMVQEAFSRLLRAPVG-DIDDE--RGWLIVVTSRLCLDHIKSASTRRE
MAV_4519|M.avium_104 AEDAVQEACAEALRAWPR-DGMPANPGGWLVTVARNRARDRLRRESARPG
MMAR_0975|M.marinum_M AEDAVQEACAEALRAWPR-DGVPDSPGGWLVTVARNRARDRLRRESARPA
MAB_3888|M.abscessus_ATCC_1997 AEDAVQEACADALRTWPR-DGIPDTPGGWLLTAARNRARDRLRRETLRPG
Mvan_3355|M.vanbaalenii_PYR-1 AEDAVQEACADALRSWPR-DGVPEVPGAWLVTTARNRARDRLRRESARPG
MSMEG_1348|M.smegmatis_MC2_155 AEDAVQEACAHAVQAWA--DGLPDNPGAWLTTVARNRALDRLRRESQRTG
TH_3917|M.thermoresistible__bu AEDAVQEALVRALTTWA--GKPPRDPKGWLITTAWRCFVDATRSDAARRR
Mflv_1191|M.gilvum_PYR-GCK AEDAVQSAWIKASITATD-DLRNP--AAYLTTVLTRECVDQLRMRQRRRE
MUL_1400|M.ulcerans_Agy99 SEETTQEIYLEVWRTASDYDATKGSPLAWLLTMAHRRAVDRVRAEQAGSQ
:*: .*. : . .:* . . * :
Mb1221|M.bovis_AF2122/97 RPQDIAAWHDG-DASVSSVDPADRVTLDDEVRLALLIMLERLGPAERVVF
Rv1189|M.tuberculosis_H37Rv RPQDIAAWHDG-DASVSSVDPADRVTLDDEVRLALLIMLERLGPAERVVF
MAV_4519|M.avium_104 KELAAVLDDI---RARTD-AADPHPVRDDELRMMFTCAHPALDRPSQLAL
MMAR_0975|M.marinum_M KELAYVVNDIGAIRARTE-HSDPHPVRDDELRMMFTCAHPALDRQSQLAL
MAB_3888|M.abscessus_ATCC_1997 KELAAVVDDI---TARTD-VADPHPVRDDELRMMFTCAHPALERTSQLAL
Mvan_3355|M.vanbaalenii_PYR-1 KELAAVLDDI---IARTDGPEVPHRVRDDELRMMFTCAHPALERPSQLAL
MSMEG_1348|M.smegmatis_MC2_155 REYAAVYEDM---TARAD--TELHPVRDDQLRMMFTCAHPALDRASQLAL
TH_3917|M.thermoresistible__bu REELIATRPP----------PGPVPAVDDTLALYFLCAHPRLSPASAVAL
Mflv_1191|M.gilvum_PYR-GCK EPLAADMIPAD------TVAADEHYLRRESISRALMVVLDRLTPSQRVAY
MUL_1400|M.ulcerans_Agy99 RESRYGAANVD-----LASDVVADSAIAGDERRRVVECLDGLTDTQRQCI
. . * .
Mb1221|M.bovis_AF2122/97 VLHEIFGLPYQQIATTIGSQASTCRQLAHRARRKINESRIAASVEPAQHR
Rv1189|M.tuberculosis_H37Rv VLHEIFGLPYQQIATTIGSQASTCRQLAHRARRKINESRIAASVEPAQHR
MAV_4519|M.avium_104 TLRLVSGLTVAEIARALLQSEAAISQRITRAKNKVRHANIPLRVPPAELL
MMAR_0975|M.marinum_M TLRLVSGLTVTEIARALLQTDAAIGQRITRAKNKIRHANIPLRVPPAELL
MAB_3888|M.abscessus_ATCC_1997 TLRLVSGLTVAEIARALLHSEAAIGQRITRAKAKIRTANIPLRVPPAELL
Mvan_3355|M.vanbaalenii_PYR-1 TLRLVSGLTVAEIARALLQSEAAVGQRITRAKAKIRHANIPLRVPPGELL
MSMEG_1348|M.smegmatis_MC2_155 TLRLISGLTAAEIARALLQSETAVRQRITRAKNKIRKANIPLRVPPAELL
TH_3917|M.thermoresistible__bu TLRAVGGLTTRQIAQAYLVPESTMAQRISRAKHTIADVQPGR---PGDLR
Mflv_1191|M.gilvum_PYR-GCK VLHDVFAVPFQEIAETLGTSPASAKKHASRARERIHRTVQIPAAATIDS-
MUL_1400|M.ulcerans_Agy99 ELAYYGGLTYAEVSQRLATNLSTIKSRMRDALRGLRNCLDAS--------
* .:. ::: :: . * :
Mb1221|M.bovis_AF2122/97 ---------VVTRAFIEACSN-----------------------------
Rv1189|M.tuberculosis_H37Rv ---------VVTRAFIEACSN-----------------------------
MAV_4519|M.avium_104 GERTPHVLGCVYSVFTEGYWSTAGPSAIRDDLCDEGIRLGAELCALLPHE
MMAR_0975|M.marinum_M PERTPHVLGCIYSVFTEGYWATGGPSAIRDELCDEGVRLAQELCALMPQE
MAB_3888|M.abscessus_ATCC_1997 PERTPHVLSCIYSVFTEGYWSTGGPSAIRDELCDEGVRLAGELCRLMPQE
Mvan_3355|M.vanbaalenii_PYR-1 AQRTPHVLACIYSVFTEGYWSTAGPSAIRDELCDEAVRLTGELCVAMPEE
MSMEG_1348|M.smegmatis_MC2_155 PERTPHVLACIYSVFTEGYWSTAGPSAIRDELCDEGVRLAAELCALLPDD
TH_3917|M.thermoresistible__bu -----TVLRVLYLVFNEGYTG-------EVDLAEEAIRLARRLVAVT-DD
Mflv_1191|M.gilvum_PYR-GCK ---------AVVEAFLAAAAG-----------------------------
MUL_1400|M.ulcerans_Agy99 --------------------------------------------------
Mb1221|M.bovis_AF2122/97 ---GDLDTLLEVLDPGVAGEIDAR---------------KGVVVVGADRV
Rv1189|M.tuberculosis_H37Rv ---GDLDTLLEVLDPGVAGEIDAR---------------KGVVVVGADRV
MAV_4519|M.avium_104 REAHALSALMLLHDSRRATRVDAHGVPVPLEEQDRTRWDRRRITAGLDRL
MMAR_0975|M.marinum_M PETHALAALVLLHDSRRATRVDEAGALVPLDEQDRSRWDHGRIARGLDRL
MAB_3888|M.abscessus_ATCC_1997 REANALAALVLLHDSRRLERMDSAGALVPLEEQDRTRWDHGRISRGLSQL
Mvan_3355|M.vanbaalenii_PYR-1 PEGHALAALVLLHDSRRATRTDGRGTLVPLEEQDRRRWDRGKIARGLEQL
MSMEG_1348|M.smegmatis_MC2_155 RDAHALSALVLLHDSRRSTRTDHTGALIPLDEQDRTRWDRGRIARGLDQL
TH_3917|M.thermoresistible__bu PEVAGLLALFLLHHARRPARTRADGSLVPLAEQDRSVWRRDLIAEGVGIL
Mflv_1191|M.gilvum_PYR-GCK ---GDTATMVALMADDCVRVADPT---------------LLPAHTPAVVI
MUL_1400|M.ulcerans_Agy99 --------------------------------------------------
Mb1221|M.bovis_AF2122/97 GPTILRH----WSHPATVLVAQPVCGQPAVLAFVNRALAGVLALSIEAGK
Rv1189|M.tuberculosis_H37Rv GPTILRH----WSHPATVLVAQPVCGQPAVLAFVNRALAGVLALSIEAGK
MAV_4519|M.avium_104 RYAEGSS--GAYLPQAVIAALHATAPSWEETDWVTICAAYDRLWQLTRSP
MMAR_0975|M.marinum_M RRASGSR--GPYLPQAVIAALHASAPSWEHTDWTTICAAYDRLLQLTDSP
MAB_3888|M.abscessus_ATCC_1997 RLAAGST--GPYLPQAVIAALHATAASWEETDWHAICLAYDRLLTMTDSP
Mvan_3355|M.vanbaalenii_PYR-1 RRAGGSP--GPYLPQAVIAAVHATAPCWEQTDWVTICAAYDRLLGIADSP
MSMEG_1348|M.smegmatis_MC2_155 RLAEGAT--GPYLPQAVIAAVHATAPGWQATDWSTICLAYDRLLQQADSP
TH_3917|M.thermoresistible__bu QAALARDRLGEYQAQAAIAALHADAQRVEDTDWVQIVEWYDELVALTGSP
Mflv_1191|M.gilvum_PYR-GCK GDSAVAD-----ETSLFIDRIRVSAPMLVDGRTVHVIAPGGHELAVIDIT
MUL_1400|M.ulcerans_Agy99 --------------------------------------------------
Mb1221|M.bovis_AF2122/97 ITKIHVLVQPSTLDPLRAELGGG---------------------------
Rv1189|M.tuberculosis_H37Rv ITKIHVLVQPSTLDPLRAELGGG---------------------------
MAV_4519|M.avium_104 VVAANRALAIGLRDGPDAGLAALEEVD-EPKLERSNLIATLRADLLRRAG
MMAR_0975|M.marinum_M VVLANRALAVGFRDGPDAGLAALEEVAHDPRLSHSNLVASARADLLRRAG
MAB_3888|M.abscessus_ATCC_1997 VVLVNRALAIGLRDAPEAGLAALEKVAHDPRLARSNLAATVRADLLRRAG
Mvan_3355|M.vanbaalenii_PYR-1 VVRANRAMAVGFRDGPDAGLAALETVADDPRLARSPLVATVRADLLRRAG
MSMEG_1348|M.smegmatis_MC2_155 VVRANRALAIGFRDGHAAGLAALDEVADDPLLARSNTVAVIRADLLRRAG
TH_3917|M.thermoresistible__bu VVRLNRAVAVGAAAGPRAGLAALAELD--PELPRHTAAAAY---LHEQAG
Mflv_1191|M.gilvum_PYR-GCK VTDGRIARIEITRTHPSGRR------------------------------
MUL_1400|M.ulcerans_Agy99 --------------------------------------------------
Mb1221|M.bovis_AF2122/97 --------------------------------------------------
Rv1189|M.tuberculosis_H37Rv --------------------------------------------------
MAV_4519|M.avium_104 RPAEALPWYRIASQSNGS-EPGREFLRRRIAECTSAAESATGDAFPENGR
MMAR_0975|M.marinum_M RGADALRWYRVALDSNGS-EPSRGFLQRRIAECQG---------------
MAB_3888|M.abscessus_ATCC_1997 RYDEAIDWYRTALSANGS-DPGRDFLRRRIAECLNNSG------------
Mvan_3355|M.vanbaalenii_PYR-1 RDDEAVVSYRHALAANGS-IPGREFLARRIAECGG---------------
MSMEG_1348|M.smegmatis_MC2_155 RTGEAIHWYGVALEHHAINEPAAAFLRRRLAECESATAAN----------
TH_3917|M.thermoresistible__bu DIATAADLYAEAAAKADN-LAERNHLTLRAATLRRRI-------------
Mflv_1191|M.gilvum_PYR-GCK --------------------------------------------------
MUL_1400|M.ulcerans_Agy99 --------------------------------------------------
Mb1221|M.bovis_AF2122/97 -
Rv1189|M.tuberculosis_H37Rv -
MAV_4519|M.avium_104 R
MMAR_0975|M.marinum_M -
MAB_3888|M.abscessus_ATCC_1997 -
Mvan_3355|M.vanbaalenii_PYR-1 -
MSMEG_1348|M.smegmatis_MC2_155 -
TH_3917|M.thermoresistible__bu -
Mflv_1191|M.gilvum_PYR-GCK -
MUL_1400|M.ulcerans_Agy99 -