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M. thermoresistible (build 8) TH_3789 (-)

annotation: putative short-chain dehydrogenase/reductase SDR
coordinates: 2964765 - 2965634
length: 290

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_3789--100% (290)putative short-chain dehydrogenase/reductase SDR
M. thermoresistible (build 8)TH_3237-2e-6848.77% (285) PUTATIVE short-chain dehydrogenase/reductase SDR
M. thermoresistible (build 8)TH_3434-5e-6142.50% (280) PUTATIVE short-chain dehydrogenase/reductase SDR

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0706fabG3e-5640.78% (282) 3-ketoacyl-(acyl-carrier-protein) reductase
M. gilvum PYR-GCKMflv_2430-7e-7050.00% (286) short-chain dehydrogenase/reductase SDR
M. tuberculosis H37RvRv0687fabG3e-5640.78% (282) 3-ketoacyl-(acyl-carrier-protein) reductase
M. leprae Br4923MLBr_01807fabG12e-2130.29% (274) 3-oxoacyl-
M. abscessus ATCC 19977MAB_3844c-1e-6445.30% (287) putative short-chain dehydrogenase/reductase
M. marinum MMMAR_4754-5e-6949.83% (291) short-chain type dehydrogenase/reductase
M. avium 104MAV_2983-4e-6849.13% (287) carveol dehydrogenase
M. smegmatis MC2 155MSMEG_6031-3e-6648.08% (287) carveol dehydrogenase
M. ulcerans Agy99MUL_3392fabG1e-5141.02% (295) 3-ketoacyl-(acyl-carrier-protein) reductase
M. vanbaalenii PYR-1Mvan_4222-4e-6950.00% (286) short-chain dehydrogenase/reductase SDR

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_2430|M.gilvum_PYR-GCK          --------MAGRVEGKVAFITGAARGQGRAHAVRLAEEGADIIAVDICKQ
Mvan_4222|M.vanbaalenii_PYR-1       --------MAGRVEGKVAFITGAARGQGRAHAVRLAQEGADIIAVDICKQ
MSMEG_6031|M.smegmatis_MC2_155      --------MAGRVEGKVAFITGAARGQGRSHAVRLAEEGADIIAVDVCRR
MMAR_4754|M.marinum_M               ----MTEQLGGRVAGKVAFITGAARGQGRSHAVRLAQEGADIIAVDVCKP
MAV_2983|M.avium_104                MYAGAGAVMTGRVAGKVAFISGAARGQGRSHAVRLAQEGADIIAIDICGP
TH_3789|M.thermoresistible__bu      --------MAGRVAGKVAMITGGGRGQGRSHAVRLAEEGADIVLVDACTT
Mb0706|M.bovis_AF2122/97            -----MSARGGSLHGRVAFVTGAARAQGRSHAVRLAREGADIVALDICAP
Rv0687|M.tuberculosis_H37Rv         -----MSARGGSLHGRVAFVTGAARAQGRSHAVRLAREGADIVALDICAP
MAB_3844c|M.abscessus_ATCC_199      -----MADQP--LAGKVAFVTGAARGQGRQHAVRLAQAGADVVAIDACAP
MUL_3392|M.ulcerans_Agy99           ----MSRPLDGPLSGRVAFITGAARGQGRAHALRLARDGADVIAVDLCDQ
MLBr_01807|M.leprae_Br4923          -------------MTDAAAKVSAAPGRGK-----PAFVSRSILVTGGNRG
                                                    .*   ... .:*:      *  . .::  .    

Mflv_2430|M.gilvum_PYR-GCK          IDS-VLIPLSTPEDLAETADLVKNAGGRIHTAEVDVRDYDALKAAVDAGV
Mvan_4222|M.vanbaalenii_PYR-1       IDS-VLIPLSSPEDLAETADLVKNAGGRIHTAEVDVRDFDALKAAVDAGV
MSMEG_6031|M.smegmatis_MC2_155      ISSNEDIPASTPEDLAETVELVKGLNRRIVAEEVDVRDYDALKAVVDSGV
MMAR_4754|M.marinum_M               IVENTTIPASTPEDLAETADLVKGHNRRIFTAEADVRDYDALKAAVDAGV
MAV_2983|M.avium_104                IEN-LAYPHSTPEDLAETADLVKDLDRRIVTAQVDVRDFEALKSAVDSGV
TH_3789|M.thermoresistible__bu      INDAVTYPMATREDLERTAELVRKTGRRVQTHVADVRDFPALKAAADAAV
Mb0706|M.bovis_AF2122/97            VSGSVTYPPATSEDLGETVRAVEAEGRKVLAREVDIRDDAELRRLVADGV
Rv0687|M.tuberculosis_H37Rv         VSGSVTYPPATSEDLGETVRAVEAEGRKVLAREVDIRDDAELRRLVADGV
MAB_3844c|M.abscessus_ATCC_199      VSEYAGYEAATPEDLKETVRLVEAAGRKIIAEQADVRNGAALQSVVEEAV
MUL_3392|M.ulcerans_Agy99           IAS-VPYPLGTAEELATTVKLVEDTGARIVASQADVRDREALAAALQAGI
MLBr_01807|M.leprae_Br4923          IGLAVARRLVADGHRVAVTHRASVVPDWFFGVECDVTDNDAIGAAFKAVE
                                    :         :  .   ..  .      .     *: :   :        

Mflv_2430|M.gilvum_PYR-GCK          EEFGRLDIIVANAGIGNGGQTLDKTDEPDWDDMIGVNLSGVWKTVKAGVP
Mvan_4222|M.vanbaalenii_PYR-1       EEFGRLDIIVANAGIGNGGQLLHDTGEPDWDDMIGVNLSGVWKTVKAGVP
MSMEG_6031|M.smegmatis_MC2_155      EQLGGLDIVVANAGIGNGGATLDKTSEADWDDMIGVNLSGVWKTVKAAVP
MMAR_4754|M.marinum_M               DELGRLDIIVANAGIGNGGATLDKTSEHDWQEMIDVNLSGVWKSVKAAVP
MAV_2983|M.avium_104                EQLGRLDIIVANAGVGTDGRKLHKIRDNVWQDMIDINLTGVWHTVKAGVP
TH_3789|M.thermoresistible__bu      DEFGAIDILCANAGIISWHWSWEIP-ESAWDDVIDVNLKGVWNSVRAVVP
Mb0706|M.bovis_AF2122/97            EQFGRLDIVVANAGVLGWGRLWELT-DEQWETVIGVNLTGTWRTLRATVP
Rv0687|M.tuberculosis_H37Rv         EQFGRLDIVVANAGVLGWGRLWELT-DEQWETVIGVNLTGTWRTLRATVP
MAB_3844c|M.abscessus_ATCC_199      AQFGHIDILIANAGVLSWGRLWEMS-DQQWEDIIDTNLTGTWKTVKAVVP
MUL_3392|M.ulcerans_Agy99           DELGQVDIVVANAGIAP-----MQSGDDGWRDVIDVNLSGAYYTVEVAIP
MLBr_01807|M.leprae_Br4923          EHQGPVEVLVANAGITSDMLIMRMS-EEQFQKVIDVNLTGVFRVAKLASR
                                     . * :::: ****:           :  :  :*. **.*.:   .    

Mflv_2430|M.gilvum_PYR-GCK          HILAGGNGGSIILTSSVGGLKAYPHTGH----YVAAKHGVVGLMRTFAVE
Mvan_4222|M.vanbaalenii_PYR-1       HILAGGNGGSIILTSSVGGLKAYPHTGH----YVAAKHGVVGLMRTFAVE
MSMEG_6031|M.smegmatis_MC2_155      HLISGGNGGSIILTSSVGGLKAYPHTGH----YIAAKHGVVGLMRTFAVE
MMAR_4754|M.marinum_M               HLIAGGNGGSIVLTSSVGGMKAYPHCGN----YVAAKHGVVGLMRSFAVE
MAV_2983|M.avium_104                HVLSGGRGGSIVLTSSVGGRKAYPNTGH----YIAAKHGVIGLMRAFAVE
TH_3789|M.thermoresistible__bu      HMMKDRRGGSIVATSSAGGIRGLPYTAH----YVASKFGVVGLVKSFANE
Mb0706|M.bovis_AF2122/97            AMIDAGNGGSIVVVSSSAGLKATPGNGH----YAASKHALVALTNTLAIE
Rv0687|M.tuberculosis_H37Rv         AMIDAGNGGSIVVVSSSAGLKATPGNGH----YAASKHALVALTNTLAIE
MAB_3844c|M.abscessus_ATCC_199      TMIEAGNGGSIVIVSSVSGLKGTPGNGA----YVASKFGLTGLTKSLTIE
MUL_3392|M.ulcerans_Agy99           TMIEQGRGGSIVLISSAAGLVGISSADAGAIGYVASKHALVGLMRVYANL
MLBr_01807|M.leprae_Br4923          NMIKQRFG-RYIFMGSVVGLSGVPGQAN----YAASKSGLIGMARSLARE
                                     ::    *   :  .*  *  . .        * *:* .: .: .  :  

Mflv_2430|M.gilvum_PYR-GCK          LGAQNIRVNSVHPTNVN------TPLFMNEPTMKLFR---PDLE-NPGPD
Mvan_4222|M.vanbaalenii_PYR-1       LGAQNVRVNSVHPTNVN------TPLFMNEPTMKLFR---PDLE-NPGPE
MSMEG_6031|M.smegmatis_MC2_155      LGQHSIRVNSVHPTNVN------TPLFMNEGTMKLFR---PDLE-NPGPD
MMAR_4754|M.marinum_M               LGQHMIRVNSVHPTHVR------TPMLHNEGTFKMFR---PDLE-NPGPD
MAV_2983|M.avium_104                LGPHMIRVNAVLPTQVS------TTMVMNDQTFRLFR---PDLE-NPGPD
TH_3789|M.thermoresistible__bu      LGQYNIRVNAIHPGTVLGDGEFASAMGTLDPVPRKFFGDYPEYAPNPGHL
Mb0706|M.bovis_AF2122/97            LGEFGIRVNSIHPYSVD------TPMIEPEAMIQTFA----------KHP
Rv0687|M.tuberculosis_H37Rv         LGEFGIRVNSIHPYSVD------TPMIEPEAMIQTFA----------KHP
MAB_3844c|M.abscessus_ATCC_199      LAEYGIRVNSIHPYGVT------TPMITGDAMMKILA----------EHP
MUL_3392|M.ulcerans_Agy99           LAPHSIRVNSLHPSGVD------PPMINNEFIRHWLA---------DLVA
MLBr_01807|M.leprae_Br4923          LGSRSITANVVAPGFID------TEMTR--------------------AM
                                    *.   : .* : *  :       . :                        

Mflv_2430|M.gilvum_PYR-GCK          DMKVVGQLMHTLPI-GWVEPEDIANAVLFLASDEARFITGVTLPVDGGSC
Mvan_4222|M.vanbaalenii_PYR-1       DMKVVGQLMHTLPI-GWVEPEDIANAVLFLASDEARFITGVTLPVDGGSC
MSMEG_6031|M.smegmatis_MC2_155      DMAVVAQMMHVLPV-GWVEPRDISNAVLFLASDEARYVTGLPMTVDAGSM
MMAR_4754|M.marinum_M               DMAPICQLFHTLPI-PWVEAEDISNAVLFLASDESRYITGVTLPVDAGGC
MAV_2983|M.avium_104                DFAPISQMMHTLPV-PWVDASDISNAVLFLASDESRYVTGVSLPVDAGSL
TH_3789|M.thermoresistible__bu      RDPNADDSVRHAPR-PGTDTRDISEAVLWLASDASHFVTGISLPVDDGQV
Mb0706|M.bovis_AF2122/97            GYVHSFPPMPLQPK-GFMTPDEISDVVVWLAGDGSGALSGNQIPVDKGAL
Rv0687|M.tuberculosis_H37Rv         GYVHSFPPMPLQPK-GFMTPDEISDVVVWLAGDGSGALSGNQIPVDKGAL
MAB_3844c|M.abscessus_ATCC_199      NYLPSIAPMPLSPT-KMLEPDEISDVVLWLASDASGTLAGAQVPVDKGHL
MUL_3392|M.ulcerans_Agy99           ETGSGPGAGNALPV-QILQADDIAGALAWLVSDEARYITGVALPVDAGCV
MLBr_01807|M.leprae_Br4923          DSKYQEAALQAIPLGRIGAVEEIAGAVSFLASEDAGYISGAVIPVDGGLG
                                                *        :*: .: :*..: :  ::*  :.** *  

Mflv_2430|M.gilvum_PYR-GCK          LK-
Mvan_4222|M.vanbaalenii_PYR-1       LK-
MSMEG_6031|M.smegmatis_MC2_155      LK-
MMAR_4754|M.marinum_M               LK-
MAV_2983|M.avium_104                LK-
TH_3789|M.thermoresistible__bu      NRQ
Mb0706|M.bovis_AF2122/97            KY-
Rv0687|M.tuberculosis_H37Rv         KY-
MAB_3844c|M.abscessus_ATCC_199      TY-
MUL_3392|M.ulcerans_Agy99           NKR
MLBr_01807|M.leprae_Br4923          MGH