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M. thermoresistible (build 8) TH_3434 (-)

annotation: short-chain dehydrogenase/reductase SDR
coordinates: 3689621 - 3690442
length: 274

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_3434--100% (274)short-chain dehydrogenase/reductase SDR
M. thermoresistible (build 8)TH_3018-1e-6444.00% (275) PUTATIVE carveol dehydrogenase
M. thermoresistible (build 8)TH_3789-4e-6142.50% (280) PUTATIVE putative short-chain dehydrogenase/reductase SDR

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0706fabG1e-11772.53% (273) 3-ketoacyl-(acyl-carrier-protein) reductase
M. gilvum PYR-GCKMflv_5072fabG1e-13082.05% (273) 3-ketoacyl-(acyl-carrier-protein) reductase
M. tuberculosis H37RvRv0687fabG1e-11772.53% (273) 3-ketoacyl-(acyl-carrier-protein) reductase
M. leprae Br4923MLBr_01740-4e-2935.81% (215) short chain dehydrogenase
M. abscessus ATCC 19977MAB_3844c-6e-9961.54% (273) putative short-chain dehydrogenase/reductase
M. marinum MMMAR_1016-1e-11874.73% (273) short-chain dehydrogenase/reductase
M. avium 104MAV_4486-1e-11571.43% (273) short chain dehydrogenase
M. smegmatis MC2 155MSMEG_1410fabG1e-13486.45% (273) 3-ketoacyl-(acyl-carrier-protein) reductase
M. ulcerans Agy99MUL_0768-1e-10872.76% (257) 3-ketoacyl-(acyl-carrier-protein) reductase
M. vanbaalenii PYR-1Mvan_1286fabG1e-13384.62% (273) 3-ketoacyl-(acyl-carrier-protein) reductase

CLUSTAL 2.0.9 multiple sequence alignment


TH_3434|M.thermoresistible__bu      ------------VAFITGAARGQGRAHAIRLAEEGADIIAIDVCGPVSDT
MSMEG_1410|M.smegmatis_MC2_155      -MATVGKTLEGRVAFVTGAARGQGRAHAVRLADEGADIIAIDVCAPVDDT
Mflv_5072|M.gilvum_PYR-GCK          MPMSSGTPLEGRVALITGAARGQGRAHAIRLAADGADIVALDVCKPVSES
Mvan_1286|M.vanbaalenii_PYR-1       MPMASAAPLEGRVALITGAARGQGRAHAVRLAAEGADIIAIDVCGPVSES
Mb0706|M.bovis_AF2122/97            -MSARGGSLHGRVAFVTGAARAQGRSHAVRLAREGADIVALDICAPVSGS
Rv0687|M.tuberculosis_H37Rv         -MSARGGSLHGRVAFVTGAARAQGRSHAVRLAREGADIVALDICAPVSGS
MAV_4486|M.avium_104                -MSGQAGSLQGRVAFITGAARGQGRSHAVRLAAEGADIIACDICAPVSAS
MMAR_1016|M.marinum_M               -MAAQTGSLDGRVAFVTGAARAQGRSHAVRLAREGADIIAMDICGPVSET
MUL_0768|M.ulcerans_Agy99           ----------------------------MRLAREGADIIAMDICGPVSES
MAB_3844c|M.abscessus_ATCC_199      ---MADQPLAGKVAFVTGAARGQGRQHAVRLAQAGADVVAIDACAPVSEY
MLBr_01740|M.leprae_Br4923          -MVKTAQYFVGKRCFVTGAASGIGRATALRLAAYGAELYLTDR-------
                                                                :***  **::   *        

TH_3434|M.thermoresistible__bu      ITYPPATEDDLAETVRAVEATGRKVLAR-TADIRDLAAQQQIVAEGMERF
MSMEG_1410|M.smegmatis_MC2_155      ITYPSATPEDLAETVAAVEATGRKVLAR-EVDIRDLAAQQQVVADGVEQF
Mflv_5072|M.gilvum_PYR-GCK          VTYPMPTSEDLAETVRLVEETGRKVLAR-EVDIRDLAAQQQLVADAVEQF
Mvan_1286|M.vanbaalenii_PYR-1       ITYSMPTSEDLAETVRLVEATGRKVLAR-EVDIRDLAAQQQVVADGVEQF
Mb0706|M.bovis_AF2122/97            VTYPPATSEDLGETVRAVEAEGRKVLAR-EVDIRDDAELRRLVADGVEQF
Rv0687|M.tuberculosis_H37Rv         VTYPPATSEDLGETVRAVEAEGRKVLAR-EVDIRDDAELRRLVADGVEQF
MAV_4486|M.avium_104                VTYAPASPEDLDETARLVEDQGRKALTR-VLDVRDDAALRELVADGMEQF
MMAR_1016|M.marinum_M               ITYAPATAADLSETIRAVESEGRKVLAR-QADVRDSAALQQLVADGVEEF
MUL_0768|M.ulcerans_Agy99           ITYAPATAADLSETIRAVESEGRKVLAR-QADVRDSAALQQLVADGVEEF
MAB_3844c|M.abscessus_ATCC_199      AGYEAATPEDLKETVRLVEAAGRKIIAE-QADVRNGAALQSVVEEAVAQF
MLBr_01740|M.leprae_Br4923          ------HCDGLAQTVSEARALGAQVPEYRALDISDYDEVAAFGADIHARH
                                             .* :*   ..  * :       *: :      .  :   ..

TH_3434|M.thermoresistible__bu      GRLDIVVANAGVLSWGRLWEMSEEQWDTVIDVNLNGTWRTIRAVVPAMIE
MSMEG_1410|M.smegmatis_MC2_155      GRLDIVVANAGVLSWGRIFEMSPEQWDTVVDVNLNGTWRTIRAAVPAMIE
Mflv_5072|M.gilvum_PYR-GCK          GRLDIVVANAGVLSWGRIWEMSEDQWDTVVDVNLNGTWRTIRAAVPAMIE
Mvan_1286|M.vanbaalenii_PYR-1       GRLDIVVANAGVLSWGRIWEMSEEQWDTVVDVNLNGTWRTVRAAVPAMIE
Mb0706|M.bovis_AF2122/97            GRLDIVVANAGVLGWGRLWELTDEQWETVIGVNLTGTWRTLRATVPAMID
Rv0687|M.tuberculosis_H37Rv         GRLDIVVANAGVLGWGRLWELTDEQWETVIGVNLTGTWRTLRATVPAMID
MAV_4486|M.avium_104                GRLDVVVANAGVLSWGRVWELTDEQWDTVIGVNLTGTWRTLRATVPAMIE
MMAR_1016|M.marinum_M               GRLDVVVANAGVLGWGRLWELTDEQWDTVIGVNLSGTWRTLRAAVPAMIE
MUL_0768|M.ulcerans_Agy99           GRLDVMVANAGVFGWGRLWELTDEQWDTVIGVNLSGTWRTLRAAVPAMIE
MAB_3844c|M.abscessus_ATCC_199      GHIDILIANAGVLSWGRLWEMSDQQWEDIIDTNLTGTWKTVKAVVPTMIE
MLBr_01740|M.leprae_Br4923          PSMDIVMNIAGVSVWGTVDRLTHDQWSNVVAINLMGPIHIIETFVPAILA
                                      :*:::  ***  ** : .:: :**. ::  ** *. : :.: **::: 

TH_3434|M.thermoresistible__bu      AGNGGSIIIVSSSAGLKATPGNGHYAASKHGLVALTNALAIEVGEYGIRV
MSMEG_1410|M.smegmatis_MC2_155      AGNGGSIIIVSSSAGLKATPGNGHYAASKHGLVALTNSLALEVGEYGIRV
Mflv_5072|M.gilvum_PYR-GCK          AGNGGSIIIVSSSAGLKATPGNAHYAASKHGLVALTNALALEAGEFGIRV
Mvan_1286|M.vanbaalenii_PYR-1       AGNGGSIVIVSSSAGLKATPGNAHYAASKHGLVALTNALAIEAGEFGIRV
Mb0706|M.bovis_AF2122/97            AGNGGSIVVVSSSAGLKATPGNGHYAASKHALVALTNTLAIELGEFGIRV
Rv0687|M.tuberculosis_H37Rv         AGNGGSIVVVSSSAGLKATPGNGHYAASKHALVALTNTLAIELGEFGIRV
MAV_4486|M.avium_104                AGNGGSIVVVSSSAGLKATPGNGHYSASKHGLTALTNTLAIELGEYGIRV
MMAR_1016|M.marinum_M               AGNGGSIIVVSSSAGLKATPGNGHYAASKHGLVALTNTLAIELGEYDIRV
MUL_0768|M.ulcerans_Agy99           AGNGGSIIVVSSSAGLKATPGNGHYAASKHGLVALTNTLAIELGEYDIGV
MAB_3844c|M.abscessus_ATCC_199      AGNGGSIVIVSSVSGLKGTPGNGAYVASKFGLTGLTKSLTIELAEYGIRV
MLBr_01740|M.leprae_Br4923          AGRGGHLVNVSSAAGLVALPWHAAYSASKYGLRGLSEVLRFDLARYRIGV
                                    **.** :: *** :** . * :. * ***..* .*:: * :: ..: * *

TH_3434|M.thermoresistible__bu      NSIHPYSIDTPMIERDAMMAVFAKHPNYLHSFAPMPLHPVNREGDGGRQE
MSMEG_1410|M.smegmatis_MC2_155      NSIHPYSIDTPMIEPEAMAQVFAKYPNYLHSFAPMPYQPVG-EGAEGLST
Mflv_5072|M.gilvum_PYR-GCK          NSIHPYSIDTPMIEKDAMMEIFSKYPTFLHSFAPMPFKPVARDGKPGLQE
Mvan_1286|M.vanbaalenii_PYR-1       NSIHPYSIDTPMIEKDAMMEIFSKYPTYLHSFAPMPFKPVAREGKPGLQE
Mb0706|M.bovis_AF2122/97            NSIHPYSVDTPMIEPEAMIQTFAKHPGYVHSFPPMPLQPKG---------
Rv0687|M.tuberculosis_H37Rv         NSIHPYSVDTPMIEPEAMIQTFAKHPGYVHSFPPMPLQPKG---------
MAV_4486|M.avium_104                NSIHPYSVETPMIEPEAMMEIFARHPSFVHSFPPMPVQPNG---------
MMAR_1016|M.marinum_M               NSIHPYSVETPMIEPDVMMQVFGEHPRFLHSFPPMPLQYKG---------
MUL_0768|M.ulcerans_Agy99           NSIHPYSVETPMIEPDVMMQVFGEHPRFLHSFPPMPLQYKG---------
MAB_3844c|M.abscessus_ATCC_199      NSIHPYGVTTPMITGDAMMKILAEHPNYLPSIAPMPLSPTK---------
MLBr_01740|M.leprae_Br4923          SVVVPGAVRTPLVDTIEIAGVDRQDPRFSRWVDRFRGHAVSAERAAEKIL
                                    . : * .: **::    :     . * :   .  :               

TH_3434|M.thermoresistible__bu      FMTPE-----------------------------EVADVVAWLAGDGSAT
MSMEG_1410|M.smegmatis_MC2_155      FMTPE-----------------------------EVSDVVAWLAGDGSAT
Mflv_5072|M.gilvum_PYR-GCK          FMTVE-----------------------------EVSDVVAWLAGDSSAT
Mvan_1286|M.vanbaalenii_PYR-1       FMTVE-----------------------------EVADVVAWLAGDASST
Mb0706|M.bovis_AF2122/97            FMTPD-----------------------------EISDVVVWLAGDGSGA
Rv0687|M.tuberculosis_H37Rv         FMTPD-----------------------------EISDVVVWLAGDGSGA
MAV_4486|M.avium_104                FMTAD-----------------------------EVADVVAWLAGDGSGT
MMAR_1016|M.marinum_M               LMTSE-----------------------------EVSDVVVWLAGDGSGT
MUL_0768|M.ulcerans_Agy99           LMTSE-----------------------------EVSDVVVWLAGDGSGT
MAB_3844c|M.abscessus_ATCC_199      MLEPD-----------------------------EISDVVLWLASDASGT
MLBr_01740|M.leprae_Br4923          AGVAKNRYLIYTSHDIRVLYGFKRLAWWPYGVVMKQVNVVFTRALRPSPA
                                        .                             :  :**   *   * :

TH_3434|M.thermoresistible__bu      LSGSQIAVDRGVMKY-----------
MSMEG_1410|M.smegmatis_MC2_155      LSGSQIAVDRGVMKY-----------
Mflv_5072|M.gilvum_PYR-GCK          ISGSQIAVDRGTMKY-----------
Mvan_1286|M.vanbaalenii_PYR-1       ISGSQIAVDRGTMKY-----------
Mb0706|M.bovis_AF2122/97            LSGNQIPVDKGALKY-----------
Rv0687|M.tuberculosis_H37Rv         LSGNQIPVDKGALKY-----------
MAV_4486|M.avium_104                LTGTQIPVDKGALKY-----------
MMAR_1016|M.marinum_M               LSGAQIPVDKGALKY-----------
MUL_0768|M.ulcerans_Agy99           LSGAQIPVDKGALKY-----------
MAB_3844c|M.abscessus_ATCC_199      LAGAQVPVDKGHLTY-----------
MLBr_01740|M.leprae_Br4923          TMRCVEPIKVGVYSQPRSGEGGKSGN
                                          .:. *  .