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YAGAGAVMTGRVAGKVAFISGAARGQGRSHAVRLAQEGADIIAIDICGPIENLAYPHSTPEDLAETADLV KDLDRRIVTAQVDVRDFEALKSAVDSGVEQLGRLDIIVANAGVGTDGRKLHKIRDNVWQDMIDINLTGVW HTVKAGVPHVLSGGRGGSIVLTSSVGGRKAYPNTGHYIAAKHGVIGLMRAFAVELGPHMIRVNAVLPTQV STTMVMNDQTFRLFRPDLENPGPDDFAPISQMMHTLPVPWVDASDISNAVLFLASDESRYVTGVSLPVDA GSLLK*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_2983 | - | - | 100% (286) | carveol dehydrogenase |
| M. avium 104 | MAV_0896 | - | e-122 | 75.18% (282) | carveol dehydrogenase ((+)-trans-carveol dehydrogenase) |
| M. avium 104 | MAV_0846 | - | e-117 | 73.84% (279) | carveol dehydrogenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2771 | - | 8e-66 | 50.00% (276) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. gilvum PYR-GCK | Mflv_2430 | - | 1e-113 | 70.14% (278) | short-chain dehydrogenase/reductase SDR |
| M. tuberculosis H37Rv | Rv2750 | - | 8e-66 | 50.00% (276) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. leprae Br4923 | MLBr_01807 | fabG1 | 6e-21 | 28.62% (276) | 3-oxoacyl- |
| M. abscessus ATCC 19977 | MAB_0072c | - | 4e-80 | 52.36% (275) | putative short chain dehydrogenase/reductase |
| M. marinum M | MMAR_4754 | - | 1e-119 | 74.01% (277) | short-chain type dehydrogenase/reductase |
| M. smegmatis MC2 155 | MSMEG_4849 | - | 1e-118 | 73.67% (281) | carveol dehydrogenase |
| M. thermoresistible (build 8) | TH_3237 | - | 1e-118 | 72.30% (278) | PUTATIVE short-chain dehydrogenase/reductase SDR |
| M. ulcerans Agy99 | MUL_3392 | fabG | 5e-64 | 45.64% (287) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. vanbaalenii PYR-1 | Mvan_4222 | - | 1e-113 | 69.78% (278) | short-chain dehydrogenase/reductase SDR |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2771|M.bovis_AF2122/97 -------MIDRPLEGKVAFITGAARGLGRAHAVRLAADGANIIAVDICEQ
Rv2750|M.tuberculosis_H37Rv -------MIDRPLEGKVAFITGAARGLGRAHAVRLAADGANIIAVDICEQ
MUL_3392|M.ulcerans_Agy99 ----MSRPLDGPLSGRVAFITGAARGQGRAHALRLARDGADVIAVDLCDQ
MMAR_4754|M.marinum_M ----MTEQLGGRVAGKVAFITGAARGQGRSHAVRLAQEGADIIAVDVCKP
MSMEG_4849|M.smegmatis_MC2_155 --------MSGRVEGKVAFVTGAARGQGRSHALRLAQEGADIIAIDICGP
Mflv_2430|M.gilvum_PYR-GCK --------MAGRVEGKVAFITGAARGQGRAHAVRLAEEGADIIAVDICKQ
Mvan_4222|M.vanbaalenii_PYR-1 --------MAGRVEGKVAFITGAARGQGRAHAVRLAQEGADIIAVDICKQ
TH_3237|M.thermoresistible__bu --------MAGRLEGKVAFITGAARGQGRAHAVRMAQEGADIIAVDICRQ
MAV_2983|M.avium_104 MYAGAGAVMTGRVAGKVAFISGAARGQGRSHAVRLAQEGADIIAIDICGP
MAB_0072c|M.abscessus_ATCC_199 --------MTGRLTGKVALVTGAARGIGRAQAVRFAQEGADIIALDICAP
MLBr_01807|M.leprae_Br4923 ---------MTDAAAKVSAAPGRGKPAFVSRSILVTGGNRGIGLAVARRL
.:*: .* .: :::: .: . .:
Mb2771|M.bovis_AF2122/97 IASV---PYPLSTADDLAATVELVEDAGGGIVARQGDVRDRASLSVALQA
Rv2750|M.tuberculosis_H37Rv IASV---PYPLSTADDLAATVELVEDAGGGIVARQGDVRDRASLSVALQA
MUL_3392|M.ulcerans_Agy99 IASV---PYPLGTAEELATTVKLVEDTGARIVASQADVRDREALAAALQA
MMAR_4754|M.marinum_M IVEN--TTIPASTPEDLAETADLVKGHNRRIFTAEADVRDYDALKAAVDA
MSMEG_4849|M.smegmatis_MC2_155 IRPGAETAIPASTSDDLAETANLVKGLDRRVVTAEVDVRDAAAIKAAVDS
Mflv_2430|M.gilvum_PYR-GCK IDSV---LIPLSTPEDLAETADLVKNAGGRIHTAEVDVRDYDALKAAVDA
Mvan_4222|M.vanbaalenii_PYR-1 IDSV---LIPLSSPEDLAETADLVKNAGGRIHTAEVDVRDFDALKAAVDA
TH_3237|M.thermoresistible__bu IDSV---QIPLASPEDLAETADLVKGLNRRIYTAEVDVRDFDALKAAVDT
MAV_2983|M.avium_104 IENL---AYPHSTPEDLAETADLVKDLDRRIVTAQVDVRDFEALKSAVDS
MAB_0072c|M.abscessus_ATCC_199 VHTT---ITPPATRADLDKTSELVESAGRRVIPGVVDVRNLRDVQTFTQD
MLBr_01807|M.leprae_Br4923 VADG-----------HRVAVTHRASVVPDWFFGVECDVTDNDAIGAAFKA
: . . . .. . ** : : .
Mb2771|M.bovis_AF2122/97 GLDEFGRLDIVVANAGIAMM-----QAGDDGWRDVIDVNLTGVFHTVQVA
Rv2750|M.tuberculosis_H37Rv GLDEFGRLDIVVANAGIAMM-----QAGDDGWRDVIDVNLTGVFHTVQVA
MUL_3392|M.ulcerans_Agy99 GIDELGQVDIVVANAGIAPM-----QSGDDGWRDVIDVNLSGAYYTVEVA
MMAR_4754|M.marinum_M GVDELGRLDIIVANAGIGNGGATLDKTSEHDWQEMIDVNLSGVWKSVKAA
MSMEG_4849|M.smegmatis_MC2_155 GVEQLGRLDIIVANAGIGNGGDTLDQTSEEDWDEMIDINLSGVWKSVKAG
Mflv_2430|M.gilvum_PYR-GCK GVEEFGRLDIIVANAGIGNGGQTLDKTDEPDWDDMIGVNLSGVWKTVKAG
Mvan_4222|M.vanbaalenii_PYR-1 GVEEFGRLDIIVANAGIGNGGQLLHDTGEPDWDDMIGVNLSGVWKTVKAG
TH_3237|M.thermoresistible__bu GVEQLGRLDIIVANAGIGNGGETLDKTSEGDWTDMIDVNLAGVWKTVKAG
MAV_2983|M.avium_104 GVEQLGRLDIIVANAGVGTDGRKLHKIRDNVWQDMIDINLTGVWHTVKAG
MAB_0072c|M.abscessus_ATCC_199 AVTEFGGLDIVCATAGITSR-RMLLDMPESDWQTMLDVNLTGVWHTTRAA
MLBr_01807|M.leprae_Br4923 VEEHQGPVEVLVANAGITSD-MLIMRMSEEQFQKVIDVNLTGVFRVAKLA
. * :::: *.**: : : ::.:**:*.: .. .
Mb2771|M.bovis_AF2122/97 IPTLIEQGTGGSIVLISSAAGLVGIGSSDPGSLGYAAAKHGVVGLMRAYA
Rv2750|M.tuberculosis_H37Rv IPTLIEQGTGGSIVLISSAAGLVGIGSSDPGSLGYAAAKHGVVGLMRAYA
MUL_3392|M.ulcerans_Agy99 IPTMIEQGRGGSIVLISSAAGLVGISSADAGAIGYVASKHALVGLMRVYA
MMAR_4754|M.marinum_M VPHLIAGGNGGSIVLTSSVGGMKAYPHCG----NYVAAKHGVVGLMRSFA
MSMEG_4849|M.smegmatis_MC2_155 VPHIVAGGRGGSIVLTSSVGGLKAYPHCG----NYVAAKHGVVGLMRGFA
Mflv_2430|M.gilvum_PYR-GCK VPHILAGGNGGSIILTSSVGGLKAYPHTG----HYVAAKHGVVGLMRTFA
Mvan_4222|M.vanbaalenii_PYR-1 VPHILAGGNGGSIILTSSVGGLKAYPHTG----HYVAAKHGVVGLMRTFA
TH_3237|M.thermoresistible__bu VPHILAGGRGGSIILTSSVGGLKAYPHTG----HYVAAKHGVVGLMRTFA
MAV_2983|M.avium_104 VPHVLSGGRGGSIVLTSSVGGRKAYPNTG----HYIAAKHGVIGLMRAFA
MAB_0072c|M.abscessus_ATCC_199 TPHLIARG-GGAMVLVSSIAGLRGLVGVS----HYVAAKHGVVGLMRSLA
MLBr_01807|M.leprae_Br4923 SRNMIKQRFGRYIFMG-SVVGLSGVPGQA----NYAASKSGLIGMARSLA
:: * :.: * * . * *:* .::*: * *
Mb2771|M.bovis_AF2122/97 NHLAPQNIRVNSVHPCGVDTPMINNEFFQQWLT-------TADMDAPHNL
Rv2750|M.tuberculosis_H37Rv NHLAPQNIRVNSVHPCGVDTPMINNEFFQQWLT-------TADMDAPHNL
MUL_3392|M.ulcerans_Agy99 NLLAPHSIRVNSLHPSGVDPPMINNEFIRHWLAD-----LVAETGSGPGA
MMAR_4754|M.marinum_M VELGQHMIRVNSVHPTHVRTPMLHNEGTFKMFRPDLENPGPDDMAPICQL
MSMEG_4849|M.smegmatis_MC2_155 VELGQHNIRVNTVHPTHVATPMLHNEGTFKMFRPDLENPGPDDMAPICQM
Mflv_2430|M.gilvum_PYR-GCK VELGAQNIRVNSVHPTNVNTPLFMNEPTMKLFRPDLENPGPDDMKVVGQL
Mvan_4222|M.vanbaalenii_PYR-1 VELGAQNVRVNSVHPTNVNTPLFMNEPTMKLFRPDLENPGPEDMKVVGQL
TH_3237|M.thermoresistible__bu VELGQHNIRVNSVHPTNVNTPLFMNEPTMKLFRPDLENPGPEDLKVVAQM
MAV_2983|M.avium_104 VELGPHMIRVNAVLPTQVSTTMVMNDQTFRLFRPDLENPGPDDFAPISQM
MAB_0072c|M.abscessus_ATCC_199 IELAPHKIRVNTVHPTNVDTPMIQNEFVRTLFRPDLEQPTREDFAAAAKT
MLBr_01807|M.leprae_Br4923 RELGSRSITANVVAPGFIDTEMTR----------------AMDSKYQEAA
*. : : .* : * : . : :
Mb2771|M.bovis_AF2122/97 GNALPVELVQP-TDIANAVAWLASEEARYVTGVTLPVDAGFVNKR
Rv2750|M.tuberculosis_H37Rv GNALPVELVQP-TDIANAVAWLASEEARYVTGVTLPVDAGFVNKR
MUL_3392|M.ulcerans_Agy99 GNALPVQILQA-DDIAGALAWLVSDEARYITGVALPVDAGCVNKR
MMAR_4754|M.marinum_M FHTLPIPWVEA-EDISNAVLFLASDESRYITGVTLPVDAGGCLK-
MSMEG_4849|M.smegmatis_MC2_155 FHTLPIPWVEP-IDISNAVLFLASDEARYITGVTLPVDAGSCLK-
Mflv_2430|M.gilvum_PYR-GCK MHTLPIGWVEP-EDIANAVLFLASDEARFITGVTLPVDGGSCLK-
Mvan_4222|M.vanbaalenii_PYR-1 MHTLPIGWVEP-EDIANAVLFLASDEARFITGVTLPVDGGSCLK-
TH_3237|M.thermoresistible__bu MHTLPIGWVEP-EDIANAVLFLASDEARYITGVTLPVDGGSCLK-
MAV_2983|M.avium_104 MHTLPVPWVDA-SDISNAVLFLASDESRYVTGVSLPVDAGSLLK-
MAB_0072c|M.abscessus_ATCC_199 MNLLDLPWVEP-LDIANASLFLASDEARYITSVSLPVDAGSTQR-
MLBr_01807|M.leprae_Br4923 LQAIPLGRIGAVEEIAGAVSFLASEDAGYISGAVIPVDGGLGMGH
: : : : . :*:.* :*.*::: :::.. :***.*