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aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_3559 | - | - | 100% (343) | AMP-dependent synthetase and ligase |
| M. thermoresistible (build 8) | TH_3166 | - | 1e-87 | 51.19% (336) | PUTATIVE putative AMP-dependent synthetase and ligase |
| M. thermoresistible (build 8) | TH_4313 | - | 1e-52 | 39.49% (352) | PUTATIVE putative AMP-dependent synthetase and ligase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0566c | fadD8 | 3e-32 | 31.52% (349) | acyl-CoA synthetase |
| M. gilvum PYR-GCK | Mflv_4362 | - | 1e-141 | 73.21% (336) | AMP-dependent synthetase and ligase |
| M. tuberculosis H37Rv | Rv0551c | fadD8 | 3e-32 | 31.52% (349) | acyl-CoA synthetase |
| M. leprae Br4923 | MLBr_02661 | - | 5e-32 | 32.41% (361) | acyl-CoA synthetase |
| M. abscessus ATCC 19977 | MAB_3435 | - | 3e-32 | 31.02% (361) | acyl-CoA synthetase |
| M. marinum M | MMAR_4025 | - | 1e-137 | 71.68% (339) | long-chain fatty-acid CoA ligase |
| M. avium 104 | MAV_1580 | - | 1e-149 | 80.12% (332) | AMP-dependent synthetase and ligase |
| M. smegmatis MC2 155 | MSMEG_2217 | - | 1e-146 | 75.81% (339) | AMP-dependent synthetase and ligase |
| M. ulcerans Agy99 | MUL_3890 | - | 1e-135 | 71.09% (339) | long-chain fatty-acid CoA ligase |
| M. vanbaalenii PYR-1 | Mvan_1982 | - | 1e-140 | 72.92% (336) | AMP-dependent synthetase and ligase |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_4025|M.marinum_M --------------------------------------------MSNHPL
MUL_3890|M.ulcerans_Agy99 --------------------------------------------MSNHPL
MAV_1580|M.avium_104 --------------------------------------------MPRHPL
TH_3559|M.thermoresistible__bu --------------------------------------------------
Mflv_4362|M.gilvum_PYR-GCK ----------------------------------------------MHPL
Mvan_1982|M.vanbaalenii_PYR-1 --------------------------------------------MMVHRL
MSMEG_2217|M.smegmatis_MC2_155 ---------------------------------------------MAHPL
MLBr_02661|M.leprae_Br4923 ---------------------MKSESITSSRAPVEQIDARLTGQFESPSI
Mb0566c|M.bovis_AF2122/97 MSTAGDDAVGVPPACGGRSDAVGVPQLARESGAMRDQDCSGELLRSPTHN
Rv0551c|M.tuberculosis_H37Rv MSTAGDDAVGVPPACGGRSDAVGVPQLARESGAMRDQDCSGELLRSPTHN
MAB_3435|M.abscessus_ATCC_1997 --------------------------------------------------
MMAR_4025|M.marinum_M SQRIADTLDLQPDARAVEYDR-----AWLSWGQLGAATRRVAALAARQPS
MUL_3890|M.ulcerans_Agy99 SQRIAVTLDLQPDARAVEYDR-----AWLSLGQLGAATRRVAALAAKQPS
MAV_1580|M.avium_104 VQRIADVLDLEPHGRAIEYGG-----QWFSWAQLGATARQVAARTTG---
TH_3559|M.thermoresistible__bu --------------------------------------------------
Mflv_4362|M.gilvum_PYR-GCK SRRIAEVMALDASAPAIQFER-----RWVTWGQIAESARHVSTVVGS---
Mvan_1982|M.vanbaalenii_PYR-1 SQRIDDVLALAPAGRAIQFDG-----DWVTWEQIGTLAQRISDVVGT---
MSMEG_2217|M.smegmatis_MC2_155 SQRIADVLDLDPDAGAIQFDG-----QWSCWGQIAALAGHIEKITGP---
MLBr_02661|M.leprae_Br4923 ASLVEAAAIRNPSAPALVVTDNRIVVSYRDLLRLVDDLTVQLALGGLLPG
Mb0566c|M.bovis_AF2122/97 GHLLVGALKRHQNKPVLFLGDTR--LTGGQLADRISQYIQAFEALGAGTG
Rv0551c|M.tuberculosis_H37Rv GHLLVGALKRHQNKPVLFLGDTR--LTGGQLADRISQYIQAFEALGAGTG
MAB_3435|M.abscessus_ATCC_1997 -MYPGAHAAQFPDKPAVVMAGSGATLTYGELDRQSRRLARHWYDSGLRKG
MMAR_4025|M.marinum_M PEIGILLRSRPAQMAAFLGVLLSGATVVTINPSR--GDERTRADIAALEL
MUL_3890|M.ulcerans_Agy99 PEIGILLRNRPAQMAAFLGVLLAGATVVTINPSR--GDERTRADIAALEL
MAV_1580|M.avium_104 TEVGMLLRNRPWQVAAFLGVLLGGGTVVVVNPSR--GDERTRADLARLRL
TH_3559|M.thermoresistible__bu --------------------------------------------------
Mflv_4362|M.gilvum_PYR-GCK GTAGIMLRNTPSHVAALLGVLSGGGTVVVINPSR--GDERTRADIEALQL
Mvan_1982|M.vanbaalenii_PYR-1 ARAGIMLRNRPVHVAALLGVLRGGGTVVVINPSR--GDDRTRSDVEALNL
MSMEG_2217|M.smegmatis_MC2_155 ARVGIMLRNHPVHVAALLGVLAAGGTVVVINPAR--GDDRTRADLEALAL
MLBr_02661|M.leprae_Br4923 DRVALCAASNIEFVVGLLAASRAGLIVVPLDPALPVNEQCIRSQAAGVRV
Mb0566c|M.bovis_AF2122/97 VAVGLLSLNRPEVLMIIGAGQARGYRRTALHPLGSLADHAYVLNDAGISS
Rv0551c|M.tuberculosis_H37Rv VAVGLLSLNRPEVLMIIGAGQARGYRRTALHPLGSLADHAYVLNDAGISS
MAB_3435|M.abscessus_ATCC_1997 DHVALLSDNVPEVFVVYWAALRSGLYITSVNHHLAPAEVSYIVNDSGSSA
MMAR_4025|M.marinum_M PLIAGSDED---------------LGLLVTNTTDSATVSLSDLFDHPGEP
MUL_3890|M.ulcerans_Agy99 PLIAGSDED---------------LGLLVTNTTDSATVSLSDLFDHPGEP
MAV_1580|M.avium_104 PLIIGEPDD---------------LAALVT--DDTPTMPISRLADPPGP-
TH_3559|M.thermoresistible__bu --------------------------------------------------
Mflv_4362|M.gilvum_PYR-GCK PTLIGLAED---------------LESLAPGTT--ATTMALGDIDTTPEI
Mvan_1982|M.vanbaalenii_PYR-1 PIIIGSSED---------------LAALAPDTA--ATTVAVDGFDEPPTL
MSMEG_2217|M.smegmatis_MC2_155 PVVVGLAED---------------LAHLMPAHSPRTTRVAIAGLDTEPVV
MLBr_02661|M.leprae_Br4923 TLVDSLALEGV-SDQRAATMRYWPIAVSYGSVTGASEGSLLVHLDDTAAL
Mb0566c|M.bovis_AF2122/97 LIIDPNPMFVERALALLEQVDSLQQILTIGPVPDALKHVAVDLSAEAAKY
Rv0551c|M.tuberculosis_H37Rv LIIDPNPMFVERALALLEQVDSLQQILTIGPVPDALKHVAVDLSAEAAKY
MAB_3435|M.abscessus_ATCC_1997 LVVAAGVREQA----------EAILDDTPAVTLRLAFGGDVRGYDSYEDA
MMAR_4025|M.marinum_M GDHTTRGAG---ADVAVRMLTSGTTGPPKRVDLSYDMLARSVMGPAPDRD
MUL_3890|M.ulcerans_Agy99 GGHTTRGAG---ADVAVRMLTSGTTGPPNRVDLSYDMLARSVMGPAPDRD
MAV_1580|M.avium_104 -AAPPAAAP---RSVAVRMLTSGTTGPPKRIDLGYDMLARSVLGVEPGTA
TH_3559|M.thermoresistible__bu ----------------VRMLTSGTTGPPKRVDLTYDMLAHSVIGPDFREA
Mflv_4362|M.gilvum_PYR-GCK TGGS-PSEGQHRPGVAVRMPTSGTTGPPKRVDLTYDMLARSVMGRDPDTA
Mvan_1982|M.vanbaalenii_PYR-1 HRGN-ASDDAGRPGVAVWMLTSGTTGPPKRVDLTYDMLARSVMGPDSDHD
MSMEG_2217|M.smegmatis_MC2_155 TAAESPATDAGGPGVAVWMLTSGTTGPPKRVDLTYDMLARSVMGREPEKC
MLBr_02661|M.leprae_Br4923 HPVTSTPDG-LRHDDAMIMFTGGTTGLPKMVPWTDGNIAGSVHAIITAYQ
Mb0566c|M.bovis_AF2122/97 QPQPLVAADLPPDQVIGLTYTGGTTGKPKGVIGTAQSIATMTSIQLAEWE
Rv0551c|M.tuberculosis_H37Rv QPQPLVAADLPPDQVIGLTYTGGTTGKPKGVIGTAQSIATMTSIQLAEWE
MAB_3435|M.abscessus_ATCC_1997 LDGASDEPLPAQPAGSDMLYSSGTTGRPKGIKVPLTDRQVDEPNPFAMLF
:.**** *: :
MMAR_4025|M.marinum_M PAPTEPRRGVAIVN-SPLVHIGGVYRVLQCIAQARPFVLLDR---FELNA
MUL_3890|M.ulcerans_Agy99 PAPTEPRRGVAIVN-SPLVHIGGVYRVLQCIAQARPFVLLDR---FELNA
MAV_1580|M.avium_104 PAPTEPRRGVAIVN-SPLVHIGGVFRVLQCIADARPFVLLER---FELNA
TH_3559|M.thermoresistible__bu GPPAELRRGVAIVN-APLVHIGGVYRVLQCIAAGRRFVLLER---FELQR
Mflv_4362|M.gilvum_PYR-GCK PSPTELRQGVAIVN-SPLVHVGGVFRILLCLAEARPFVLLPK---FELHS
Mvan_1982|M.vanbaalenii_PYR-1 SAPTDLRRGVAIVN-SPLVHVGGVFRVLLCVAEARPFVLLPK---FELKQ
MSMEG_2217|M.smegmatis_MC2_155 PAPTELRRGVAIVN-SPLVHVGGVFRVLLCIAEARPFVLLPK---FELQR
MLBr_02661|M.leprae_Br4923 LGPQD----ATVVV-MPLYHGHGLIAALLSTLASGGVVLLPARARFSART
Mb0566c|M.bovis_AF2122/97 WPANP----RFLMC-TPLSHAGAAFFTPTVIKGGE-MIVLAK---FDPAE
Rv0551c|M.tuberculosis_H37Rv WPANP----RFLMC-TPLSHAGAAFFTPTVIKGGE-MIVLAK---FDPAE
MAB_3435|M.abscessus_ATCC_1997 AHLYGFNAETVYLSPAPIYHAAPLRFCGFVQSMGGTAVVMER---FEAEE
: *: * . ::: *.
MMAR_4025|M.marinum_M WAAAVRKHRPRTVSLVPAALRTVLHSDLTR---ADLASVRTVTCGTAPLA
MUL_3890|M.ulcerans_Agy99 RAAAVRKHRPRTVSLVPAALRTVLHSDPTR---ADLASVRTVTCGTAPLA
MAV_1580|M.avium_104 WAAAVRRHRPRAVSLVPAALRTVLHSDLPR---ADLESIQVVTCGTAPLS
TH_3559|M.thermoresistible__bu WAEAVRTHRPRAVSLVPAALRMVLHSDLTR---EDLASIQAVTSGTAPLS
Mflv_4362|M.gilvum_PYR-GCK WAEAVREHRPAAVSLVPAALRMVLHSDLTR---DDLAGVRVVTSGTAPLS
Mvan_1982|M.vanbaalenii_PYR-1 WADAVREHRPRAVSLVPAALRMVLHSDLTR---EDLDGIRVVTSGTAPLS
MSMEG_2217|M.smegmatis_MC2_155 WAAAVREHRPRAVSLVPAALRTVLHSDLTR---EDLAGVRVVTSGTAPLS
MLBr_02661|M.leprae_Br4923 FWDDIDAVAATWYTAAPAIHRILLELASTQSFRSKRAKLRFIRSCSAPLT
Mb0566c|M.bovis_AF2122/97 VLRIIEEQRITATMLVPSMLYALLDHPDSHT--RDLSSLETVYYGASAIN
Rv0551c|M.tuberculosis_H37Rv VLRIIEEQRITATMLVPSMLYALLDHPDSHT--RDLSSLETVYYGASAIN
MAB_3435|M.abscessus_ATCC_1997 ALAAIEKYRITHSQWVPTMFVRMLKLPKEIRDRYDVSSLKVAVHAAAPCP
: .*: :*. . :. ::.
MMAR_4025|M.marinum_M PDDADAFTEKYGIPVLTSYAATEFGGGVAGWTLADHSR--YWHTKRGSVG
MUL_3890|M.ulcerans_Agy99 PDDADAFTEKYGIPVLTSYAATEFGGGVAGWTLADHSR--YWHTKRGSVG
MAV_1580|M.avium_104 ADDADAFTEKYGIPVLTSYAATEFGGGVAGWTLADHRR--YWRVKRGSVG
TH_3559|M.thermoresistible__bu ADDADAFTEKFGIPVLTSYAATEFGGGVAGWTLADHRR--YWRTKRGSSG
Mflv_4362|M.gilvum_PYR-GCK ADDAEAFTAKFGIPVLTSYAATEFGGGVAGWTLADHRK--YWQDKRGSVG
Mvan_1982|M.vanbaalenii_PYR-1 ADDADAFTEKFGIPVLTSYAATEFGGGVAGWTLKDHQR--FWQHKRGSVG
MSMEG_2217|M.smegmatis_MC2_155 ADDADAFTEKFGIPVLTSYAATEFGGGVAGWTLPDHGK--YWKDKRGSVG
MLBr_02661|M.leprae_Br4923 QETAQALREEFLAPVICAFGMTEATHQVTTTNIKWFGQGENPTVTNGLVG
Mb0566c|M.bovis_AF2122/97 PVRLAEAIRRFGPIFAQYYGQSEAPMVITYLAKGDHDE-----KRLTSCG
Rv0551c|M.tuberculosis_H37Rv PVRLAEAIRRFGPIFAQYYGQSEAPMVITYLAKGDHDE-----KRLTSCG
MAB_3435|M.abscessus_ATCC_1997 VEVKQSMIDWWGPILYEYYSSTEG-NGVTFIDCATWLK------RPGSVG
: . :. :* :: . *
MMAR_4025|M.marinum_M RANPGTQLRIVDTEGAPVERASLGLLEVKPAQLGV---------------
MUL_3890|M.ulcerans_Agy99 RANPGTQLRIVDTEGAPVERASLGLLEVKPAQLGV---------------
MAV_1580|M.avium_104 RANPGAALRVVAEDGTPLGPDEIGLMEVKPGQLGP---------------
TH_3559|M.thermoresistible__bu RATGGAQLRVVDEQGNPLGPDQPGVLEVKPGQLGP---------------
Mflv_4362|M.gilvum_PYR-GCK RANPGARLRVVDDNRDPVPPGEPGLLEVIPAQLAD---------------
Mvan_1982|M.vanbaalenii_PYR-1 RANPGAQLRVVDDNGEPVPPGQQGLLEVIPAQLAG---------------
MSMEG_2217|M.smegmatis_MC2_155 RANPGAQLRVVDENGAPLGPDEPGLLEVIPAQMGP---------------
MLBr_02661|M.leprae_Br4923 QS-TGVQIRIVGSDGQPLPPDTVGEVWLRGSTVVRGYLGDPAIT---AAN
Mb0566c|M.bovis_AF2122/97 RPTLFARVALLDEHGKPVKQGEVGEICVSGPLLAGGYWNLPDET---SRT
Rv0551c|M.tuberculosis_H37Rv RPTLFARVALLDEHGKPVKQGEVGEICVSGPLLAGGYWNLPDET---SRT
MAB_3435|M.abscessus_ATCC_1997 SAALGVLH-ICDETGAELPAGEAGLVYFEREELPFSYHNDDEKTRSACHP
. . : : * : . :
MMAR_4025|M.marinum_M -SAPWVRTTDVARIDADGFVWIVGRADQAIIRGGFKVLPDDVGAALESHP
MUL_3890|M.ulcerans_Agy99 -SAPWVRTTDVARIDADGFVWIVGRADQAIIRGGFKVLPDDVRAALESHP
MAV_1580|M.avium_104 -DADWLRTTDMARIDADGFVWIVGRADQAIIRGGFKVMPDDVRAALESHP
TH_3559|M.thermoresistible__bu -DADWLRTTDLARIDADGFLWILGRADQAIIRGGFKIMPDDVRAALERHP
Mflv_4362|M.gilvum_PYR-GCK -TGEWMQTTDVARIDEDGFLWILGRADQAIIRGGFKVMPDDVRSALESHA
Mvan_1982|M.vanbaalenii_PYR-1 -RSGWMQTTDLARIDEDGFVWILGRADQAIIRGGFKVMPDDVKNALESHP
MSMEG_2217|M.smegmatis_MC2_155 -GSPWMRTTDLARIDADGFLWVLGRADQAIIRGGFKVMPDDVRAALESHP
MLBr_02661|M.leprae_Br4923 FTHGWLRTGDLGSLSVTGDLRIRGRIKELINRSGEKISPERVEGVLASHH
Mb0566c|M.bovis_AF2122/97 FKDGWLHTGDLAREDSDGFYYIVDRVKDMIVTGGFNVFPREVEDVVAEHP
Rv0551c|M.tuberculosis_H37Rv FKDGWLHTGDLAREDSDGFYYIVDRVKDMIVTGGFNVFPREVEDVVAEHP
MAB_3435|M.abscessus_ATCC_1997 AHDTWTTTGDIGYVDEDGFLYLTDRKAFMIISGGVNIYPQEIENALALHP
* * *:. . * : .* * .* :: * : .: *
MMAR_4025|M.marinum_M AVAAAAVVGRSDQRLGQTPVAMVELRGSADIG-------GAELVEYLRTR
MUL_3890|M.ulcerans_Agy99 AVAAAAVVGRSDQRLGQTPVAMVELRGSADIG-------GAELVEYLRTR
MAV_1580|M.avium_104 AVAGAAVVARPDPRLGETPVAMVELRAPSTT---------DALVEHLRER
TH_3559|M.thermoresistible__bu AVRGAAVVGIPDARLGETPAALVELHDGAAAG-------TDELTAFLRER
Mflv_4362|M.gilvum_PYR-GCK AVAGAAVVGRPDPRLGETPVALVELRPGATAS-------PEELSAYLQTR
Mvan_1982|M.vanbaalenii_PYR-1 AVAGASVVGRPDPRLGETPVALVQLRPGMSAE-------PDELLNYLQKR
MSMEG_2217|M.smegmatis_MC2_155 AVLGASVIGVADERLGETPVAMVELRG--PAT-------PDELAGYLQGR
MLBr_02661|M.leprae_Br4923 NVMEVAVFGDPDKVYGETVTAVIVPREVIAPT-------PSELAVFCRDR
Mb0566c|M.bovis_AF2122/97 AVAQVCVVGAPDEKWGEAVTAVVVLRSNAARDEPAIEAMTAEIQAAVKQR
Rv0551c|M.tuberculosis_H37Rv AVAQVCVVGAPDEKWGEAVTAVVVLRSNAARDEPAIEAMTAEIQAAVKQR
MAB_3435|M.abscessus_ATCC_1997 AVLDVAVIGVPDAEMGESVKAVVQPADSSAAPR----ELAAELTDFLRER
* ..*.. .* *:: *:: : : *
MMAR_4025|M.marinum_M LSGYEIPTQISIVAEIPRTASGKPDLGAIRHYFGAAGSRT-DHGG
MUL_3890|M.ulcerans_Agy99 LSGYEIPTQISIVAEIPRTASGKPDLGAIRHYFGAAGSRT-DHGG
MAV_1580|M.avium_104 LARYEIPTEIAIVDALPRTPSGKADLAAVRGYFAERPTVLRDHAR
TH_3559|M.thermoresistible__bu LAPYEVPTEIAVVDALPRTPSGKADLGAVRRTLAPAGHDG-----
Mflv_4362|M.gilvum_PYR-GCK LARYEIPTALILTDAIPRTPSGKPDLTAVRARLAQP---------
Mvan_1982|M.vanbaalenii_PYR-1 LARYEIPGELVITDAIPRTASGKPDLTAVRSHFAQS---------
MSMEG_2217|M.smegmatis_MC2_155 LARYEIPTRITIVDAIPRTPSGKADLRAVRDHLESGG--------
MLBr_02661|M.leprae_Br4923 LAAFEVPTRFQEASALPHTAKGSLDRRAVAEQFAHRG--------
Mb0566c|M.bovis_AF2122/97 KGSVQAPKRVVVVDSLPLTGLGKPDKKAVRARFWEGAGRAVG---
Rv0551c|M.tuberculosis_H37Rv KGSVQAPKRVVVVDSLPLTGLGKPDKKAVRARFWEGAGRAVG---
MAB_3435|M.abscessus_ATCC_1997 IARYKVPRSFDFTDTLPRTPTGKLAKGLLRQKYWEGAQ-------
. : * . . :* * *. :