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aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_4313 | - | - | 100% (486) | putative AMP-dependent synthetase and ligase |
| M. thermoresistible (build 8) | TH_3166 | - | 4e-61 | 37.14% (447) | PUTATIVE putative AMP-dependent synthetase and ligase |
| M. thermoresistible (build 8) | TH_3559 | - | 2e-52 | 39.49% (352) | PUTATIVE AMP-dependent synthetase and ligase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3591 | fadD3 | 9e-42 | 32.49% (477) | acyl-CoA synthetase |
| M. gilvum PYR-GCK | Mflv_4362 | - | 5e-62 | 37.72% (448) | AMP-dependent synthetase and ligase |
| M. tuberculosis H37Rv | Rv3561 | fadD3 | 2e-41 | 32.49% (477) | acyl-CoA synthetase |
| M. leprae Br4923 | MLBr_02546 | fadD2 | 2e-40 | 29.73% (481) | acyl-CoA synthetase |
| M. abscessus ATCC 19977 | MAB_4055c | - | 9e-46 | 29.67% (509) | putative acyl-CoA synthetase |
| M. marinum M | MMAR_4025 | - | 4e-55 | 34.59% (477) | long-chain fatty-acid CoA ligase |
| M. avium 104 | MAV_1880 | - | 1e-63 | 35.84% (466) | AMP-dependent synthetase and ligase |
| M. smegmatis MC2 155 | MSMEG_2217 | - | 7e-59 | 36.97% (449) | AMP-dependent synthetase and ligase |
| M. ulcerans Agy99 | MUL_3890 | - | 1e-55 | 35.18% (469) | long-chain fatty-acid CoA ligase |
| M. vanbaalenii PYR-1 | Mvan_1982 | - | 4e-61 | 37.62% (428) | AMP-dependent synthetase and ligase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3591|M.bovis_AF2122/97 -----------------------------------MINDLRTVPAALDRL
Rv3561|M.tuberculosis_H37Rv -----------------------------------MINDLRTVPAALDRL
Mflv_4362|M.gilvum_PYR-GCK ---------------------------------------MHPLSRRIAEV
Mvan_1982|M.vanbaalenii_PYR-1 -------------------------------------MMVHRLSQRIDDV
MSMEG_2217|M.smegmatis_MC2_155 --------------------------------------MAHPLSQRIADV
MMAR_4025|M.marinum_M -------------------------------------MSNHPLSQRIADT
MUL_3890|M.ulcerans_Agy99 -------------------------------------MSNHPLSQRIAVT
MAV_1880|M.avium_104 -------------------------------------MTMTSIQEALGRL
TH_4313|M.thermoresistible__bu --------------------------------------------VTLADL
MAB_4055c|M.abscessus_ATCC_199 ------------------------------MTFRSPLPDVSIPDCSVYEY
MLBr_02546|M.leprae_Br4923 MTKLRHYLERGAAEVHYLRSIFESGALGFEPPLTYAAMAVAMRKWGDLAM
Mb3591|M.bovis_AF2122/97 VRQLPDHT------ALIAEDRRFTSTELRDAVYGAAAALIALGVEPADRV
Rv3561|M.tuberculosis_H37Rv VRQLPDHT------ALIAEDRRFTSTELRDAVYGAAAALIALGVEPADRV
Mflv_4362|M.gilvum_PYR-GCK MALDASAP------AIQFERRWVTWGQIAESARHVS---TVVG---SGTA
Mvan_1982|M.vanbaalenii_PYR-1 LALAPAGR------AIQFDGDWVTWEQIGTLAQRIS---DVVG---TARA
MSMEG_2217|M.smegmatis_MC2_155 LDLDPDAG------AIQFDGQWSCWGQIAALAGHIE---KITG---PARV
MMAR_4025|M.marinum_M LDLQPDAR------AVEYDRAWLSWGQLGAATRRVA---ALAARQPSPEI
MUL_3890|M.ulcerans_Agy99 LDLQPDAR------AVEYDRAWLSLGQLGAATRRVA---ALAAKQPSPEI
MAV_1880|M.avium_104 WHADKDAR------MLQCDGQWVTWGQVRTLTERIASELAAAGCGPGGRV
TH_4313|M.thermoresistible__bu LDGVPEIA------VHTLR-ADVSRDALAAGADRLAGVLRDLGMSTGEVV
MAB_4055c|M.abscessus_ATCC_199 VFGDTGAEDSRIALIDGLTGAQTTLGELRSQIDATAAGLAERGFGIGDVA
MLBr_02546|M.leprae_Br4923 LPAMPARR-SPHRAALIDEEGTLTYKELDRAAHALANGLIAKGVRGGDGI
: .
Mb3591|M.bovis_AF2122/97 AIWSPNTWHWVVACLAIHHAGAAVVPLNTRYTATEATDILDRAGAPVLFA
Rv3561|M.tuberculosis_H37Rv AIWSPNTWHWVVACLAIHHAGAAVVPLNTRYTATEATDILDRAGAPVLFA
Mflv_4362|M.gilvum_PYR-GCK GIMLRNTPSHVAALLGVLSGGGTVVVINPSRGDERTRADIEALQLPTLIG
Mvan_1982|M.vanbaalenii_PYR-1 GIMLRNRPVHVAALLGVLRGGGTVVVINPSRGDDRTRSDVEALNLPIIIG
MSMEG_2217|M.smegmatis_MC2_155 GIMLRNHPVHVAALLGVLAAGGTVVVINPARGDDRTRADLEALALPVVVG
MMAR_4025|M.marinum_M GILLRSRPAQMAAFLGVLLSGATVVTINPSRGDERTRADIAALELPLIAG
MUL_3890|M.ulcerans_Agy99 GILLRNRPAQMAAFLGVLLAGATVVTINPSRGDERTRADIAALELPLIAG
MAV_1880|M.avium_104 AVVLGNRMESVATLIAIFRTERTLVTISPLQPAERLAADLVASGADYVLA
TH_4313|M.thermoresistible__bu AVMLPNEARTVAALFGVWRAGGVHTPLNPRAADAELRSQLEVLTPSVIVT
MAB_4055c|M.abscessus_ATCC_199 AVFLPNCSAFAVVLHGILRAGGTASTVNVLYTAEELAKQLIDSKAQLIFT
MLBr_02546|M.leprae_Br4923 AILARNHRWFVIANYGCARVGARIILLNSEFSGPQIKEVSEREGAKVIIY
.: . . . :. . :
Mb3591|M.bovis_AF2122/97 AGLFLG----ADRAAGLDRAALPALRHVVRVPVEADDGTWDEFIATGAGA
Rv3561|M.tuberculosis_H37Rv AGLFLG----ADRAAGLDRAALPALRHVVRVPVEADDGTWDEFIATGAGA
Mflv_4362|M.gilvum_PYR-GCK LAEDLE----SLAPGTT--ATTMALGDIDTTPEITGGS------------
Mvan_1982|M.vanbaalenii_PYR-1 SSEDLA----ALAPDTA--ATTVAVDGFDEPPTLHRGN------------
MSMEG_2217|M.smegmatis_MC2_155 LAEDLA----HLMPAHSPRTTRVAIAGLDTEPVVTAAES-----------
MMAR_4025|M.marinum_M SDEDLG----LLVTNTT-DSATVSLSDLFDHPGEPGDH------------
MUL_3890|M.ulcerans_Agy99 SDEDLG----LLVTNTT-DSATVSLSDLFDHPGEPGGH------------
MAV_1880|M.avium_104 PQSLWA----ERVFADAVAELGGSAFSVDGSEVVARSAAT----------
TH_4313|M.thermoresistible__bu DDQLAG----RFADFGP---PVVTGGGLDWSVARPGSAP-----------
MAB_4055c|M.abscessus_ATCC_199 VSPLLSRALEAAEIAGIDAAGVITVDPVEGRLSLADIARP----------
MLBr_02546|M.leprae_Br4923 DDEYTKVVSKAEPALGKLRALGVNPDEEEPPGSTDETLAELIAR------
Mb3591|M.bovis_AF2122/97 LDAVAARAAAVAPQDVSDILFTSGTTGRSKGVLCAHR----QSLSASASW
Rv3561|M.tuberculosis_H37Rv LDAVAARAAAVAPQDVSDILFTSGTTGRSKGVLCAHR----QSLSASASW
Mflv_4362|M.gilvum_PYR-GCK ------PSEGQHRPGVAVRMPTSGTTGPPKRVDLTYD---MLARSVMGRD
Mvan_1982|M.vanbaalenii_PYR-1 ------ASDDAGRPGVAVWMLTSGTTGPPKRVDLTYD---MLARSVMGPD
MSMEG_2217|M.smegmatis_MC2_155 ------PATDAGGPGVAVWMLTSGTTGPPKRVDLTYD---MLARSVMGRE
MMAR_4025|M.marinum_M -------TTRGAGADVAVRMLTSGTTGPPKRVDLSYD---MLARSVMGPA
MUL_3890|M.ulcerans_Agy99 -------TTRGAGADVAVRMLTSGTTGPPNRVDLSYD---MLARSVMGPA
MAV_1880|M.avium_104 ------RDARDGDAAIAIEMLTSGTTGPAKRVPLGRK---QLEVSLSAAL
TH_4313|M.thermoresistible__bu -------AERRFDADVALLQFTSGTTGPPKPVPLLHSNVLDLIDRLLAKL
MAB_4055c|M.abscessus_ATCC_199 -DLAPPQVTFDPATHLAVLPYSSGTTGKAKGVMLTHHN---LVANIAQAK
MLBr_02546|M.leprae_Br4923 ---SSSAPAPKVRKRASIIILTSGTTGTPKGANRNTP------ASLAPLG
: :***** .: .
Mb3591|M.bovis_AF2122/97 AANGKITSD------DRYLCINPFFHNFGYKAGILACLQTGATLIPHVTF
Rv3561|M.tuberculosis_H37Rv AANGKITSD------DRYLCINPFFHNFGYKAGILACLQTGATLIPHVTF
Mflv_4362|M.gilvum_PYR-GCK PDTAPSPTE----LRQGVAIVNSPLVHVGGVFRILLCLAEARPFVLLPKF
Mvan_1982|M.vanbaalenii_PYR-1 SDHDSAPTD----LRRGVAIVNSPLVHVGGVFRVLLCVAEARPFVLLPKF
MSMEG_2217|M.smegmatis_MC2_155 PEKCPAPTE----LRRGVAIVNSPLVHVGGVFRVLLCIAEARPFVLLPKF
MMAR_4025|M.marinum_M PDRDPAPTE----PRRGVAIVNSPLVHIGGVYRVLQCIAQARPFVLLDRF
MUL_3890|M.ulcerans_Agy99 PDRDPAPTE----PRRGVAIVNSPLVHIGGVYRVLQCIAQARPFVLLDRF
MAV_1880|M.avium_104 RHNDRPDVRDKPPLTGAVGMVTLPIVHIGGLWALLQALVAARPIVMLERF
TH_4313|M.thermoresistible__bu RGGSRGSRG----RAPMPNLVPLSLSLWAGIYQVLFAFRAGSGVVLMDKF
MAB_4055c|M.abscessus_ATCC_199 HLYGVQRGD-------RVLAVLPFFHIYGLVVLLNVQLKLGAELVILPRF
MLBr_02546|M.leprae_Br4923 GILSKVPFR-----AHEVTLLPAPMFHALGYLHATLAMFLGSTLVLRRRF
: : . . .: *
Mb3591|M.bovis_AF2122/97 DPLHALRAIERHRITVLPGPPTIYQSLLD--HPARKDFDLSSLRFAVTGA
Rv3561|M.tuberculosis_H37Rv DPLHALRAIERHRITVLPGPPTIYQSLLD--HPARKDFDLSSLRFAVTGA
Mflv_4362|M.gilvum_PYR-GCK ELHSWAEAVREHRPAAVSLVPAALRMVL---HSDLTRDDLAGVRVVTSGT
Mvan_1982|M.vanbaalenii_PYR-1 ELKQWADAVREHRPRAVSLVPAALRMVL---HSDLTREDLDGIRVVTSGT
MSMEG_2217|M.smegmatis_MC2_155 ELQRWAAAVREHRPRAVSLVPAALRTVL---HSDLTREDLAGVRVVTSGT
MMAR_4025|M.marinum_M ELNAWAAAVRKHRPRTVSLVPAALRTVL---HSDLTRADLASVRTVTCGT
MUL_3890|M.ulcerans_Agy99 ELNARAAAVRKHRPRTVSLVPAALRTVL---HSDPTRADLASVRTVTCGT
MAV_1880|M.avium_104 SLDGWHNAIKDHKPILIGLPPPAIREVL---NSDIPREDLASVRAVNSGT
TH_4313|M.thermoresistible__bu SPGEFAALVKRHQLRSTVLPPAALTMVL---HDES-VTDLSPLRIVRSIT
MAB_4055c|M.abscessus_ATCC_199 ELDTFLGSIANYRVDHVFVAPPVAVVLAK--HPDVDKYDVSCLRSVFSGA
MLBr_02546|M.leprae_Br4923 KPATVLEDIEKHQATAMVVVPVMLSRILDTLENLETKSDLSSLRVVFVSG
. : :: * : . *: :* .
Mb3591|M.bovis_AF2122/97 ATVPVVLVERMQSELDIDIVLTAYGLTEANGMG--TMCRPEDDAVTVATT
Rv3561|M.tuberculosis_H37Rv ATVPVVLVERMQSELDIDIVLTAYGLTEANGMG--TMCRPEDDAVTVATT
Mflv_4362|M.gilvum_PYR-GCK APLSADDAEAFTAKFGIPVLTSYAATEFGGGVAGWTLADHRKYWQDKRGS
Mvan_1982|M.vanbaalenii_PYR-1 APLSADDADAFTEKFGIPVLTSYAATEFGGGVAGWTLKDHQRFWQHKRGS
MSMEG_2217|M.smegmatis_MC2_155 APLSADDADAFTEKFGIPVLTSYAATEFGGGVAGWTLPDHGKYWKDKRGS
MMAR_4025|M.marinum_M APLAPDDADAFTEKYGIPVLTSYAATEFGGGVAGWTLADHSRYWHTKRGS
MUL_3890|M.ulcerans_Agy99 APLAPDDADAFTEKYGIPVLTSYAATEFGGGVAGWTLADHSRYWHTKRGS
MAV_1880|M.avium_104 APVDPVLVDGFLERYGIPILITYGATEFAGAVAGWTLKDFHASWTEKKGS
TH_4313|M.thermoresistible__bu APLSPVHARQFMDRFGVLVLNSYGQTELGGEVVGWTAADAREWGEAKLGS
MAB_4055c|M.abscessus_ATCC_199 APLDEQLGNAVAARLNCRVSQGYGMTELS-PVSHLIPPDRPD---IPLNS
MLBr_02546|M.leprae_Br4923 SQLGAELATRALEELGPVIYNMYGSTEIA-----FATIAGPKDLQINSAT
: : . . : . :
Mb3591|M.bovis_AF2122/97 CGRPFADFELRIADDGE----------------VLLRGPNVMVGYLDDTE
Rv3561|M.tuberculosis_H37Rv CGRPFADFELRIADDGE----------------VLLRGPNVMVGYLDDTE
Mflv_4362|M.gilvum_PYR-GCK VGRANPGARLRVVDDNR----------------DPVPPGEPGL---LEVI
Mvan_1982|M.vanbaalenii_PYR-1 VGRANPGAQLRVVDDNG----------------EPVPPGQQGL---LEVI
MSMEG_2217|M.smegmatis_MC2_155 VGRANPGAQLRVVDENG----------------APLGPDEPGL---LEVI
MMAR_4025|M.marinum_M VGRANPGTQLRIVDTEG----------------APVERASLGL---LEVK
MUL_3890|M.ulcerans_Agy99 VGRANPGTQLRIVDTEG----------------APVERASLGL---LEVK
MAV_1880|M.avium_104 VGRPFPGVRMQVIDEGG----------------TVLPPGQSGR---LQVA
TH_4313|M.thermoresistible__bu VGRPLPGIDVTIVDDEV----------------LVRTPTTLAR---RIDP
MAB_4055c|M.abscessus_ATCC_199 VGIPVPNSENKIIDTETGDEIEIPAEGESAPGELLVRGPNVMAGYLGNEE
MLBr_02546|M.leprae_Br4923 VGPVVKGVKVKILDDSG----------------KEVPRGQVGRIFVGNAF
* . : *
Mb3591|M.bovis_AF2122/97 ATAAAIDADG------WLHTGDIGAVDQAGNLRINDRLKDMYICGGFNVY
Rv3561|M.tuberculosis_H37Rv ATAAAIDADG------WLHTGDIGAVDQAGNLRITDRLKDMYICGGFNVY
Mflv_4362|M.gilvum_PYR-GCK PAQLADTGE-------WMQTTDVARIDEDGFLWILGRADQAIIRGGFKVM
Mvan_1982|M.vanbaalenii_PYR-1 PAQLAGRSG-------WMQTTDLARIDEDGFVWILGRADQAIIRGGFKVM
MSMEG_2217|M.smegmatis_MC2_155 PAQMGPGSP-------WMRTTDLARIDADGFLWVLGRADQAIIRGGFKVM
MMAR_4025|M.marinum_M PAQLGVSAP-------WVRTTDVARIDADGFVWIVGRADQAIIRGGFKVL
MUL_3890|M.ulcerans_Agy99 PAQLGVSAP-------WVRTTDVARIDADGFVWIVGRADQAIIRGGFKVL
MAV_1880|M.avium_104 SAQVADSAER------WVTTSDLAHIDEDGYLYIDGRADDVIVRGGFKIA
TH_4313|M.thermoresistible__bu AFADRLTDDG------WFHTGDLGWLDEDGFLWLDGRVSDMINRGGLKVF
MAB_4055c|M.abscessus_ATCC_199 ATAATIEPDG------FLHTGDIAVVRADGVVTIVDRLKELIKYKGYQVP
MLBr_02546|M.leprae_Br4923 PFEGYTGGGGKQIIDGLLSSGDVGYFDEHDLLYISGRDDEMIVSGGENVF
. . : *:. . . : : .* .: * ::
Mb3591|M.bovis_AF2122/97 PAEVEQVLARMDGVADAAVIGVPDQRLGEVGRAFVVARPGTGLDEASVIA
Rv3561|M.tuberculosis_H37Rv PAEVEQVLARMDGVADAAVIGVPDQRLGEVGRAFVVARPGTGLDEASVIA
Mflv_4362|M.gilvum_PYR-GCK PDDVRSALESHAAVAGAAVVGRPDPRLGETPVALVELRPGATASPEELSA
Mvan_1982|M.vanbaalenii_PYR-1 PDDVKNALESHPAVAGASVVGRPDPRLGETPVALVQLRPGMSAEPDELLN
MSMEG_2217|M.smegmatis_MC2_155 PDDVRAALESHPAVLGASVIGVADERLGETPVAMVELRG--PATPDELAG
MMAR_4025|M.marinum_M PDDVGAALESHPAVAAAAVVGRSDQRLGQTPVAMVELRGSADIGGAELVE
MUL_3890|M.ulcerans_Agy99 PDDVRAALESHPAVAAAAVVGRSDQRLGQTPVAMVELRGSADIGGAELVE
MAV_1880|M.avium_104 PETVVRALRSHGAVADAAVAGLPDDRLGQIPVAAVELKSAMTATGDELRA
TH_4313|M.thermoresistible__bu PGTVEDVLVAADGVREAAVVGVPDDRLGEVPWAFVVRAG-ERVTEEDLRA
MAB_4055c|M.abscessus_ATCC_199 PAELEALLLTHPGIGDAAVIGVPDPSSGEIPKAFVVRTD-DDLTDEAVMA
MLBr_02546|M.leprae_Br4923 PAEVEDLISGHPEVVEATAIGVDDKEWGARLRAFVVKKQDATIDEDAIKA
* : : : *:. * * * * * :
Mb3591|M.bovis_AF2122/97 YTREHLANFKTPRSVRFVDVLPRNAAGKVSKPQLRELG-----------
Rv3561|M.tuberculosis_H37Rv YTREHLANFKTPRSVRFVDVLPRNAAGKVSKPQLRELG-----------
Mflv_4362|M.gilvum_PYR-GCK YLQTRLARYEIPTALILTDAIPRTPSGKPDLTAVRARLAQP--------
Mvan_1982|M.vanbaalenii_PYR-1 YLQKRLARYEIPGELVITDAIPRTASGKPDLTAVRSHFAQS--------
MSMEG_2217|M.smegmatis_MC2_155 YLQGRLARYEIPTRITIVDAIPRTPSGKADLRAVRDHLESGG-------
MMAR_4025|M.marinum_M YLRTRLSGYEIPTQISIVAEIPRTASGKPDLGAIRHYFGAAGSRTDHGG
MUL_3890|M.ulcerans_Agy99 YLRTRLSGYEIPTQISIVAEIPRTASGKPDLGAIRHYFGAAGSRTDHGG
MAV_1880|M.avium_104 HCRASLTPYEVPAQVFVVDELPRGAALKVDRRRLVATLEKLTAVTQSG-
TH_4313|M.thermoresistible__bu WCRERLTPYRIPARFVFVDELPRNEVGKVVKRDLAARAADLVQRT----
MAB_4055c|M.abscessus_ATCC_199 FVEQKVAPHKRIRQVEFIDAIPKSAAGKILRKDLRARI-----------
MLBr_02546|M.leprae_Br4923 YVRDHLARYKVPREVIFLEELPRNPTGKVLKRELRDFEVH---------
. :: .. . . :*: * :